Gene: BMP2

650
BDA2|BMP2A|SSFSC
bone morphogenetic protein 2
protein-coding
20p12.3
Ensembl:ENSG00000125845 MIM:112261 Vega:OTTHUMG00000031833 UniprotKB:P12643
NG_023233.1
PubMed
ND|AD
6   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.368e-2 (AD)  9.101e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg23534245chr20:6751435BMP27.310e-10Alcohol consumption der day27843151

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GDNF0.756
RDH100.71
HAS20.708
SFN0.699
BTG30.695
C9orf1350.693
PIRT0.69
TNFAIP60.69
IL1RAP0.687
SPOCD10.685

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DBH-0.401
CABLES1-0.342
SCRT1-0.341
KCNQ4-0.331
TMEM191C-0.318
CRYBA2-0.311
TMEM221-0.31
EIF4E1B-0.306
CASC10-0.305
CYS1-0.304

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of ALPL protein]21910061
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of BGLAP protein]21910061
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein]21910061
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of ALPL mRNA]21910061
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of BGLAP mRNA]21910061
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of COL1A1 mRNA]21910061
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of SP7 mRNA]21910061
C0326681-nitropyrene1-nitropyrene results in increased expression of BMP2 mRNA21540303
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of BMP2 mRNA19933214
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [5-methoxypsoralen results in increased expression of BMP2 mRNA]17980360
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [imperatorin results in increased expression of BMP2 mRNA]17980360
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenic trioxide results in decreased expression of BMP2]24531206
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of BMP2 mRNA]26053266|2613693
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin promotes the reaction [FOS protein binds to BMP2 promoter]]18495116
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin promotes the reaction [JUN protein binds to BMP2 promoter]]18495116
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of BMP2 protein]18495116
C4086042-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of ALPL mRNA]]25789987
C4086042-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP2 mRNA]]25789987|2578998
C4086042-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP6 mRNA]]25789987
C4086042-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP7 mRNA]]25789987
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in increased expression of BMP2 mRNA"20406850
C0020104-(2-aminoethyl)benzenesulfonylfluoride4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA]20660070
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of BMP2 mRNA"18648102
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of ALPL mRNA]]25789987
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP2 mRNA]]25789987|2578998
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP6 mRNA]]25789987
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP7 mRNA]]25789987
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased expression of BMP2 mRNA]26053266
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of ALPL mRNA]]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP2 mRNA]]25789987|2578998
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP6 mRNA]]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP7 mRNA]]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of ALPL mRNA]]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP2 mRNA]]25789987|2578998
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP6 mRNA]]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP7 mRNA]]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of ALPL mRNA]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of and results in increased activity of ALPL protein]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP2 mRNA]25789987|2578998
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP6 mRNA]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP7 mRNA]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanoneNOG protein inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of and results in increased activity of ALPL protein]]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanoneSB 203580 inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of ALPL mRNA]]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanoneSB 203580 inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP2 mRNA]]25789987|2578998
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanoneSB 203580 inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP6 mRNA]]25789987
C000603489(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanoneSB 203580 inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP7 mRNA]]25789987
C0229095-methoxypsoralen2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [5-methoxypsoralen results in increased expression of BMP2 mRNA]17980360
C0229095-methoxypsoralen5-methoxypsoralen results in increased expression of BMP2 mRNA17980360
C0229095-methoxypsoralenSB 203580 inhibits the reaction [5-methoxypsoralen results in increased expression of BMP2 mRNA]17980360
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Bezafibrate results in increased expression of BMP2 mRNA]"21499286
D000079AcetaldehydeAcetaldehyde results in decreased expression of BMP2 protein28017615
D000079Acetaldehyde"N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Acetaldehyde results in decreased expression of BMP2 protein]"28017615
D000082AcetaminophenAcetaminophen results in decreased expression of BMP2 mRNA26690555
D000082AcetaminophenAcetaminophen results in increased expression of BMP2 protein28286204
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of BMP2 mRNA27153756
C412373AG 1879AG 1879 inhibits the reaction [resveratrol promotes the reaction [ESR1 protein binds to BMP2 promoter]]17513867
C412373AG 1879AG 1879 inhibits the reaction [resveratrol results in increased expression of BMP2 protein]17513867
D000393Air PollutantsBMP2 gene SNP results in increased susceptibility to Air Pollutants27082954
C010845aluminum chloridealuminum chloride results in decreased expression of BMP2 mRNA27470910
C010845aluminum chlorideginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of BMP2 mRNA]27470910
D000537Aluminum OxideAluminum Oxide results in increased expression of BMP2 mRNA19464052
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid affects the expression of BMP2 mRNA24098073
D000643Ammonium ChlorideAmmonium Chloride affects the expression of BMP2 mRNA16483693
D001151ArsenicArsenic affects the expression of BMP2 protein24675094
D001151ArsenicArsenic results in increased expression of BMP2 protein28903487
C006632arsenic trioxide2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenic trioxide results in decreased expression of BMP2]24531206
C006632arsenic trioxidearsenic trioxide results in decreased expression of BMP224531206
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of BMP2 mRNA"25757056
D001205Ascorbic Acid[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA15994055
D001205Ascorbic Acid[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein27387537
D001205Ascorbic AcidDexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]27387537
D001205Ascorbic Acidginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]27387537
D001205Ascorbic AcidNOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]]27387537
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased expression of BMP2 mRNA17252541
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased secretion of BMP2 protein16470222
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BMP2 mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BMP2 mRNA21839799
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of BMP2 mRNA"20382639
D004958Estradiol4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA]20660070
D004958EstradiolBMP2 protein results in increased abundance of Estradiol23313114
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA20660070
D004958EstradiolN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA]20660070
D004958Estradiol[letrozole results in decreased abundance of Estradiol] which results in decreased expression of BMP2 mRNA19620711
D004958EstradiolBMP2 protein inhibits the reaction [IGF1 protein promotes the reaction [FSHB protein results in increased abundance of Estradiol]]22067323
D004958Estradiol[BMP2 protein results in increased expression of CYP19A1 mRNA] promotes the reaction [FSHB protein results in increased abundance of Estradiol]22067323
D004958EstradiolCARTPT protein inhibits the reaction [BMP2 protein results in increased abundance of Estradiol]23313114
C031463beta-glycerophosphoric acid[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA15994055
C031463beta-glycerophosphoric acid[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein27387537
C031463beta-glycerophosphoric acidDexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]27387537
C031463beta-glycerophosphoric acidginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]27387537
C031463beta-glycerophosphoric acidNOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]]27387537
C095105bexarotene[bexarotene co-treated with Tamoxifen] results in decreased expression of BMP2 mRNA17630414
D001629Bezafibrate"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Bezafibrate results in increased expression of BMP2 mRNA]"21499286
D001629BezafibrateBezafibrate results in increased expression of BMP2 mRNA21499286
D001629BezafibrateGSK0660 inhibits the reaction [Bezafibrate results in increased expression of BMP2 mRNA]21499286
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in increased expression of BMP2 mRNA27685785
C006780bisphenol Abisphenol A affects the expression of BMP2 mRNA25181051
C025703bleomycetinbleomycetin results in increased expression of BMP2 mRNA21040473
C018475butyraldehydebutyraldehyde results in increased expression of BMP2 mRNA26079696
D002104CadmiumCadmium results in decreased expression of BMP2 mRNA20570719
D002104CadmiumCadmium results in increased expression of BMP2 mRNA20570719|2112074
D019256Cadmium Chloride[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of BMP2 mRNA12634122
D019256Cadmium ChlorideCadmium Chloride affects the expression of BMP2 mRNA18974090
D000001Calcimycinfulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA]21331654
D000001Calcimycin[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA21331654
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of BMP2 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of BMP2 mRNA17158861
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of BMP2 protein17158861
D002251Carbon Tetrachloridegadolinium chloride promotes the reaction [Carbon Tetrachloride results in increased expression of BMP2 mRNA]17158861
C086276cerivastatincerivastatin results in increased secretion of BMP2 protein16470222
C084597chlorcyclizinechlorcyclizine results in increased expression of BMP2 mRNA21058326
C023600chromic oxide[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of BMP2 mRNA12634122
C017133chromous chloride[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of BMP2 mRNA12634122
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BMP2 mRNA17602206
C007095cobaltiprotoporphyrin[cobaltiprotoporphyrin co-treated with IL1B protein] results in increased expression of BMP2 mRNA22155307
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased expression of BMP2 mRNA]19924377
C018021cobaltous chloridecobaltous chloride affects the reaction [BMP2 protein results in increased expression of ALPL mRNA]26054564
C018021cobaltous chloridecobaltous chloride affects the reaction [BMP2 protein results in increased expression of BGLAP mRNA]26054564
C018021cobaltous chloridecobaltous chloride affects the reaction [BMP2 protein results in increased expression of IBSP mRNA]26054564
C018021cobaltous chloridecobaltous chloride affects the reaction [BMP2 protein results in increased expression of SPP1 mRNA]26054564
C018021cobaltous chloride[cobaltous chloride co-treated with BMP2 protein] results in increased expression of BGLAP protein26054564
C018021cobaltous chloridecobaltous chloride results in increased expression of BMP2 mRNA19376846
D003345CorticosteroneCorticosterone results in increased expression of BMP2 mRNA15755911
D003474CurcuminCurcumin results in decreased expression of BMP2 mRNA27237783
D016572CyclosporineCyclosporine inhibits the reaction [Ionomycin results in increased expression of BMP2 mRNA]17279577
D016572CyclosporineCyclosporine results in decreased expression of BMP2 mRNA27989131
C014347decitabine[decitabine affects the methylation of BMP2 promoter] which affects the expression of BMP2 protein16314833|1631483
D003703DemecolcineDemecolcine results in increased expression of BMP2 mRNA23649840
D003907DexamethasoneDexamethasone inhibits the reaction [BMP2 protein results in increased expression of ACAN mRNA]17502159
D003907DexamethasoneDexamethasone inhibits the reaction [BMP2 protein results in increased expression of COL2A1 mRNA]17502159
D003907DexamethasoneDexamethasone inhibits the reaction [BMP2 protein results in increased expression of GREM1 mRNA]15268896
D003907DexamethasoneDexamethasone inhibits the reaction [BMP2 protein results in increased expression of SOST mRNA]15268896
D003907DexamethasoneDexamethasone promotes the reaction [BMP2 protein results in increased expression of SOX9 mRNA]17502159
D003907DexamethasoneDexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]27387537
D003907DexamethasoneDexamethasone results in decreased expression of BMP2 mRNA27387537
D003907DexamethasoneDexamethasone results in decreased expression of BMP2 protein27387537
D003907Dexamethasoneginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]27387537
D003907Dexamethasoneginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of BMP2 mRNA]27387537
D003907Dexamethasoneginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of BMP2 protein]27387537
D003907DexamethasoneNOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]]27387537
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of BMP2 mRNA21266533
D002945Cisplatin[Cisplatin co-treated with Paclitaxel] results in decreased expression of BMP2 mRNA20705681
C027118didecyldimethylammoniumdidecyldimethylammonium results in increased expression of BMP2 mRNA23537712
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of BMP2 mRNA19850644
D004051Diethylhexyl PhthalatePPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of BMP2 mRNA]19850644
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of BMP2 mRNA24535843
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BMP2 mRNA17602206
D002117CalcitriolCalcitriol promotes the reaction [BMP2 protein results in increased expression of SOST mRNA]15268896
D002117CalcitriolCalcitriol results in increased expression of BMP2 mRNA16002434
D002117CalcitriolCalcitriol results in increased expression of BMP2 protein19092814
C118739entinostatentinostat results in increased expression of BMP2 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of BMP2 mRNA15834898|1755790
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of BMP2 mRNA23649840
C004808farnesyl pyrophosphatefarnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]18310456
C082360fipronilfipronil results in increased expression of BMP2 mRNA23962444
D005419FlavonoidsFlavonoids results in decreased expression of BMP2 mRNA18035473
D005459FluoridesFluorides inhibits the reaction [potassium phosphate results in increased expression of BMP2 mRNA]24561004
D005557FormaldehydeFormaldehyde results in increased expression of BMP2 mRNA23649840
C069837fullerene C60fullerene C60 results in decreased expression of BMP2 mRNA19167457
C070081fulvestrantfulvestrant inhibits the reaction [resveratrol promotes the reaction [ESR1 protein binds to BMP2 promoter]]17513867
C070081fulvestrantfulvestrant inhibits the reaction [resveratrol results in increased expression of BMP2 mRNA]17513867
C070081fulvestrantfulvestrant inhibits the reaction [naringin results in increased secretion of BMP2 protein]23596885
C005023fulvic acidfulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA]21331654
C039281furanfuran results in decreased expression of BMP2 mRNA26194646
C038958gadolinium chloridegadolinium chloride promotes the reaction [Carbon Tetrachloride results in increased expression of BMP2 mRNA]17158861
D019833GenisteinGenistein results in increased expression of BMP2 mRNA22228119
D019833Genistein[Genistein co-treated with Methoxychlor] results in decreased expression of BMP2 mRNA21782745
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]18310456
C442759ginsenoside Rb1ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of BMP2 mRNA]27470910
C442759ginsenoside Rb1ginsenoside Rb1 results in increased expression of BMP2 mRNA27470910
C097367ginsenoside Rg3ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]27387537
C097367ginsenoside Rg3ginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of BMP2 mRNA]27387537
C097367ginsenoside Rg3ginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of BMP2 protein]27387537
C097367ginsenoside Rg3NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]]27387537
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA]17109745
D005947Glucosecobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased expression of BMP2 mRNA]19924377
D005947GlucoseGlucose results in decreased expression of BMP2 mRNA19924377
D005947Glucosetin mesoporphyrin promotes the reaction [Glucose results in decreased expression of BMP2 mRNA]19924377
C529769GSK0660GSK0660 inhibits the reaction [Bezafibrate results in increased expression of BMP2 mRNA]21499286
C577920GSK126BMP2 protein inhibits the reaction [GSK126 results in increased expression of ALPL mRNA]26424790
D006569HesperidinHesperidin results in increased expression of BMP2 mRNA21820093
D017313FenretinideFenretinide results in increased expression of BMP2 mRNA15958647
D017313FenretinideFenretinide results in increased secretion of BMP2 protein15958647
C056599icariinicariin results in increased expression of BMP2 mRNA15724410|1735582
C056599icariinicariin results in increased expression of BMP2 mRNA19747809
C056599icariinNOG protein inhibits the reaction [icariin results in increased expression of BMP2 mRNA]19747809
C056599icariinicariin results in increased expression of BMP2 mRNA16543677|2001977
C031534imperatorin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [imperatorin results in increased expression of BMP2 mRNA]17980360
C031534imperatorinimperatorin results in increased expression of BMP2 mRNA17980360
C031534imperatorinSB 203580 inhibits the reaction [imperatorin results in increased expression of BMP2 mRNA]17980360
D015759IonomycinCyclosporine inhibits the reaction [Ionomycin results in increased expression of BMP2 mRNA]17279577
D015759IonomycinIonomycin results in increased expression of BMP2 mRNA17279577
C544151jinfukangjinfukang results in increased expression of BMP2 mRNA27392435
C006552kaempferolkaempferol results in increased expression of BMP2 mRNA23989061
C006552kaempferolkaempferol results in increased expression of BMP2 protein23989061
C008261lead acetate[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of BMP2 mRNA12634122
C008261lead acetateBMP2 promotes the reaction [lead acetate results in increased expression of ACAN mRNA]17805416
C008261lead acetateBMP2 promotes the reaction [lead acetate results in increased expression of COL2A1 mRNA]17805416
C008261lead acetateBMP2 promotes the reaction [lead acetate results in increased expression of SOX9 mRNA]17805416
C008261lead acetatelead acetate inhibits the reaction [BMP2 protein results in increased phosphorylation of SMAD1 protein]17805416
C008261lead acetatelead acetate inhibits the reaction [BMP2 protein results in increased phosphorylation of SMAD5 protein]17805416
C008261lead acetatelead acetate inhibits the reaction [BMP2 protein results in increased phosphorylation of SMAD9 protein]17805416
C008261lead acetatelead acetate promotes the reaction [BMP2 results in increased expression of ACAN mRNA]17805416
C008261lead acetatelead acetate promotes the reaction [BMP2 results in increased expression of SOX9 mRNA]17805416
C008261lead acetatelead acetate results in increased activity of BMP2 protein17805416
C008261lead acetatelead acetate results in increased expression of BMP2 mRNA21829687
C008261lead acetatelead acetate results in decreased expression of BMP2 mRNA22641619
C067431letrozole[letrozole results in decreased abundance of Estradiol] which results in decreased expression of BMP2 mRNA19620711
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 inhibits the reaction [BMP2 protein results in increased expression of BGLAP protein]"26961602
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 inhibits the reaction [BMP2 protein results in increased expression of RUNX2 protein]"26961602
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 inhibits the reaction [BMP2 protein results in increased expression of SPP1 protein]"26961602
C482199lipopolysaccharide, E coli O55-B5"MIR23B mRNA inhibits the reaction [lipopolysaccharide, E coli O55-B5 inhibits the reaction [BMP2 protein results in increased expression of BGLAP protein]]"26961602
C482199lipopolysaccharide, E coli O55-B5"MIR23B mRNA inhibits the reaction [lipopolysaccharide, E coli O55-B5 inhibits the reaction [BMP2 protein results in increased expression of RUNX2 protein]]"26961602
C482199lipopolysaccharide, E coli O55-B5"MIR23B mRNA inhibits the reaction [lipopolysaccharide, E coli O55-B5 inhibits the reaction [BMP2 protein results in increased expression of SPP1 protein]]"26961602
D008070LipopolysaccharidesTriclosan promotes the reaction [Lipopolysaccharides results in increased expression of BMP2 mRNA]20507366
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of BMP2 mRNA16415329
D008070LipopolysaccharidesRanitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of BMP2 mRNA]16415329
D019808LosartanLosartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 mRNA]27412937
D019808LosartanLosartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 protein]27412937
D008344Maneb[SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP2 mRNA23017109
D008727MethotrexateMethotrexate results in increased expression of BMP2 mRNA20008919|2167806
D008731Methoxychlor[Genistein co-treated with Methoxychlor] results in decreased expression of BMP2 mRNA21782745
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of BMP2 mRNA23179753|2800136
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of BMP2 mRNA26272509
C020771methylmercury hydroxidemethylmercury hydroxide results in increased expression of BMP2 mRNA20493249
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of BMP2 mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BMP2 mRNA"26251327
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of BMP2 mRNA24810058
D0156551-Methyl-4-phenylpyridiniumBMP2 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein]20007850
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in increased expression of BMP2 mRNA]10814523
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in increased expression of BMP2 mRNA]18628692
C012258mevastatinmevastatin results in increased expression of BMP2 mRNA10814523
C012258mevastatinmevastatin results in increased expression of BMP2 protein10814523
D016685MitomycinMitomycin results in decreased expression of BMP2 mRNA25270620
C091888monoisoamyl-2,3-dimercaptosuccinate"monoisoamyl-2,3-dimercaptosuccinate results in decreased expression of BMP2 mRNA"19615344
C500085muraglitazarmuraglitazar results in decreased expression of BMP2 mRNA21515302
C531525N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide"ALDH2 protein affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide results in increased expression of BMP2 protein]"28017615
C531525N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide"N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Acetaldehyde results in decreased expression of BMP2 protein]"28017615
C531525N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide"N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide results in increased expression of and results in increased secretion of BMP2 protein"28017615
C531525N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide"N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide results in increased expression of BMP2 mRNA"28017615
C531525N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide"N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide results in increased expression of BMP2 protein"28017615
C078131N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamideN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA]20660070
C028473N-acetyl-4-benzoquinoneimineN-acetyl-4-benzoquinoneimine results in increased expression of BMP2 mRNA28286204
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of BMP2 mRNA"15585362
C005274naringin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin promotes the reaction [FOS protein binds to BMP2 promoter]]18495116
C005274naringin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin promotes the reaction [JUN protein binds to BMP2 promoter]]18495116
C005274naringinFOS protein affects the reaction [naringin results in increased expression of BMP2 mRNA]18495116
C005274naringinFOS protein affects the reaction [naringin results in increased expression of BMP2 protein]18495116
C005274naringinJUN protein affects the reaction [naringin results in increased expression of BMP2 mRNA]18495116
C005274naringinJUN protein affects the reaction [naringin results in increased expression of BMP2 protein]18495116
C005274naringinnaringin promotes the reaction [FOS protein binds to BMP2 promoter]18495116
C005274naringinnaringin promotes the reaction [JUN protein binds to BMP2 promoter]18495116
C005274naringinnaringin results in increased expression of BMP2 mRNA18495116
C005274naringinnaringin results in increased expression of BMP2 protein18495116
C005274naringinfulvestrant inhibits the reaction [naringin results in increased secretion of BMP2 protein]23596885
C005274naringinnaringin results in decreased expression of BMP2 mRNA21820093
C005274naringinnaringin results in increased secretion of BMP2 protein23596885
C005274naringin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of BMP2 protein]18495116
C005274naringinnaringin results in increased expression of BMP2 protein18495116
C028007nickel monoxidenickel monoxide results in decreased expression of BMP2 mRNA19167457
D015282OctreotideOctreotide promotes the reaction [BMP2 protein results in increased expression of ID1 mRNA]23137853
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of BMP2 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of BMP2 mRNA25729387
D010100OxygenOxygen deficiency results in increased expression of BMP2 mRNA26476374
D010100OxygenQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of BMP2 mRNA]26476374
D017239Paclitaxel[Cisplatin co-treated with Paclitaxel] results in decreased expression of BMP2 mRNA20705681
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of BMP2 mRNA26272509
D010269Paraquat[SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP2 mRNA23017109
D052638Particulate MatterParticulate Matter results in increased expression of BMP2 mRNA24769257
C517782pasireotidepasireotide promotes the reaction [BMP2 protein results in increased expression of ID1 mRNA]23137853
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in increased expression of BMP2 mRNA23602845
C023036perfluorooctanoic acidperfluorooctanoic acid affects the expression of BMP2 mRNA23941634
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of BMP2 mRNA24535843
D010634PhenobarbitalPhenobarbital affects the expression of BMP2 mRNA23091169
D010634PhenobarbitalPhenobarbital results in increased expression of BMP2 mRNA12832660
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of BMP2 mRNA26272509
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of BMP2 mRNA19710929
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in decreased expression of BMP2 mRNA27989595
C013216potassium phosphateFluorides inhibits the reaction [potassium phosphate results in increased expression of BMP2 mRNA]24561004
C013216potassium phosphatepotassium phosphate results in increased expression of BMP2 mRNA24561004
D011374Progesterone4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA]20660070
D011374ProgesteroneBMP2 protein results in decreased abundance of Progesterone20639315|2331311
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA20660070
D011374ProgesteroneN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of BMP2 mRNA]20660070
D011374ProgesteroneNOG protein inhibits the reaction [BMP2 protein results in decreased abundance of Progesterone]20639315
D011374ProgesteroneProgesterone results in decreased expression of BMP2 mRNA20660070
D011374ProgesteroneNCOA2 protein affects the reaction [Progesterone results in decreased expression of BMP2 mRNA]17556502
D011374ProgesteronePGR protein affects the reaction [Progesterone results in decreased expression of BMP2 mRNA]17556502
D011374ProgesteroneProgesterone results in decreased expression of BMP2 mRNA17556502
D011374Progesterone[BMP2 protein results in decreased expression of STAR mRNA] inhibits the reaction [FSHB protein results in increased abundance of Progesterone]22067323
D011374ProgesteroneIGF1 protein inhibits the reaction [BMP2 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]]22067323
D011441PropylthiouracilPropylthiouracil affects the expression of BMP2 mRNA24780913
D011794QuercetinQuercetin results in increased expression of BMP2 mRNA16996034
D011794Quercetin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of BMP2 mRNA]26053266|2613693
D011794Quercetin4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased expression of BMP2 mRNA]26053266
D011794QuercetinQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of BMP2 mRNA]26476374
D011794QuercetinQuercetin results in increased expression of BMP2 mRNA26053266|2613693
D011794QuercetinSB 203580 inhibits the reaction [Quercetin results in increased expression of BMP2 mRNA]26136938
C502851quinocetonequinocetone results in increased expression of BMP2 mRNA27046791
D011899RanitidineRanitidine inhibits the reaction [Lipopolysaccharides results in decreased expression of BMP2 mRNA]16415329
C052785rebamipiderebamipide results in increased expression of BMP2 mRNA15104358
C059514resveratrolAG 1879 inhibits the reaction [resveratrol promotes the reaction [ESR1 protein binds to BMP2 promoter]]17513867
C059514resveratrolAG 1879 inhibits the reaction [resveratrol results in increased expression of BMP2 protein]17513867
C059514resveratrolFOXA1 protein promotes the reaction [resveratrol results in increased expression of BMP2 protein]17513867
C059514resveratrolfulvestrant inhibits the reaction [resveratrol promotes the reaction [ESR1 protein binds to BMP2 promoter]]17513867
C059514resveratrolfulvestrant inhibits the reaction [resveratrol results in increased expression of BMP2 mRNA]17513867
C059514resveratrolresveratrol inhibits the reaction [TNF protein results in increased expression of BMP2 mRNA]16973825
C059514resveratrolresveratrol promotes the reaction [ESR1 protein binds to BMP2 promoter]17513867
C059514resveratrolresveratrol results in increased expression of BMP2 mRNA17513867
C059514resveratrolresveratrol results in increased expression of BMP2 protein17513867
C059514resveratrolTamoxifen inhibits the reaction [resveratrol promotes the reaction [ESR1 protein binds to BMP2 promoter]]17513867
C059514resveratrolresveratrol results in decreased expression of BMP2 mRNA25338179
C059514resveratrolresveratrol results in increased expression of BMP2 mRNA17513867
C009172rhodiolosiderhodioloside results in increased expression of BMP2 mRNA24055767
C089730rosiglitazonerosiglitazone results in decreased expression of BMP2 mRNA21515302
C541923sandostatinLARsandostatinLAR results in increased expression of BMP2 mRNA17210224
C093642SB 203580SB 203580 results in decreased expression of BMP2 mRNA20660070
C093642SB 203580SB 203580 inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of ALPL mRNA]]25789987
C093642SB 203580SB 203580 inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP2 mRNA]]25789987|2578998
C093642SB 203580SB 203580 inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP6 mRNA]]25789987
C093642SB 203580SB 203580 inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of BMP7 mRNA]]25789987
C093642SB 203580SB 203580 inhibits the reaction [5-methoxypsoralen results in increased expression of BMP2 mRNA]17980360
C093642SB 203580SB 203580 inhibits the reaction [imperatorin results in increased expression of BMP2 mRNA]17980360
C093642SB 203580SB 203580 inhibits the reaction [Quercetin results in increased expression of BMP2 mRNA]26136938
C078903seocalcitolseocalcitol results in increased expression of BMP2 mRNA12040012
D012822Silicon DioxideSilicon Dioxide results in increased expression of BMP2 mRNA21540303
D012834SilverSilver results in increased expression of BMP2 mRNA27131904
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in increased expression of BMP2 mRNA]10814523
D019821SimvastatinSimvastatin results in increased expression of BMP220381859
D019821SimvastatinSimvastatin results in increased expression of BMP2 mRNA10814523|1725254
D019821SimvastatinSimvastatin results in increased secretion of BMP2 protein16470222
D019821Simvastatinfarnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]18310456
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]18310456
D019821SimvastatinSimvastatin inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]18310456
D019821SimvastatinSimvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD1 protein]]18310456
D019821SimvastatinSimvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD5 protein]]18310456
D019821SimvastatinSimvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD9 protein]]18310456
D019821SimvastatinSimvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]18310456
D019821SimvastatinSimvastatin results in increased expression of BMP212914771
D019821SimvastatinSimvastatin results in increased expression of BMP2 mRNA11162604|2041788
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in increased expression of BMP2 mRNA]18628692
D019821SimvastatinSimvastatin results in increased expression of BMP2 mRNA18628692|1991265
D019821SimvastatinSimvastatin results in increased expression of BMP2 protein19292885
D019821SimvastatinSimvastatin results in increased expression of BMP217721043
C017947sodium arsenitesodium arsenite affects the expression of BMP2 mRNA19615344
C017947sodium arsenite[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of BMP2 mRNA12634122
C017947sodium arsenitesodium arsenite results in increased expression of BMP2 mRNA10910055
D012999SomanSoman results in increased expression of BMP2 mRNA19281266
D053260SootSoot results in decreased expression of BMP2 mRNA26551751
D014284Triiodothyronine[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of BMP2 mRNA14761676
D013629TamoxifenTamoxifen inhibits the reaction [resveratrol promotes the reaction [ESR1 protein binds to BMP2 promoter]]17513867
D013629Tamoxifen[bexarotene co-treated with Tamoxifen] results in decreased expression of BMP2 mRNA17630414
D013739TestosteroneTestosterone results in decreased expression of BMP2 mRNA22138414
D013749Tetrachlorodibenzodioxin[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of BMP2 mRNA14761676
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of BMP2 mRNA25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of BMP2 mRNA24035824
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BMP2 mRNA19933214
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BMP2 mRNA11752688
D013755Tetradecanoylphorbol Acetatefulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA]21331654
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA21331654
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of BMP2 mRNA10910055
C055421tin mesoporphyrintin mesoporphyrin promotes the reaction [Glucose results in decreased expression of BMP2 mRNA]19924377
C055421tin mesoporphyrintin mesoporphyrin results in decreased expression of BMP2 mRNA19924377
C009495titanium dioxide[Vitallium analog binds to titanium dioxide] which results in decreased expression of BMP2 mRNA23825117
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased methylation of BMP2 gene26756918
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of BMP2 mRNA27237783
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of BMP2 mRNA25729387
D019772TopotecanTopotecan results in increased expression of BMP2 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of BMP2 mRNA"19682533
D014212TretinoinTretinoin promotes the reaction [BMP2 protein results in increased expression of SOST mRNA]15268896
D014212TretinoinTretinoin results in increased expression of BMP2 mRNA17196394|2193413
D014212TretinoinTretinoin results in increased expression of BMP2 mRNA16604517
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of BMP2 mRNA26272509
C012589trichostatin Atrichostatin A results in increased expression of BMP2 mRNA23562654
C012589trichostatin Atrichostatin A results in increased expression of BMP2 protein23562654
D014260TriclosanTriclosan promotes the reaction [Lipopolysaccharides results in increased expression of BMP2 mRNA]20507366
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of BMP2 mRNA19042947
C057693troglitazonetroglitazone results in decreased expression of BMP2 mRNA21515302
C057693troglitazoneBMP2 protein promotes the reaction [troglitazone results in increased expression of LPL mRNA]19122273
C057693troglitazone[troglitazone co-treated with BMP2 protein] results in increased expression of CFD mRNA19122273
C057693troglitazonetroglitazone inhibits the reaction [BMP2 protein results in increased expression of ALPL mRNA]19122273
C057693troglitazonetroglitazone inhibits the reaction [BMP2 protein results in increased expression of COL1A2 mRNA]19122273
C057693troglitazonetroglitazone inhibits the reaction [BMP2 protein results in increased expression of RUNX2 mRNA]19122273
C057693troglitazonetroglitazone inhibits the reaction [BMP2 protein results in increased expression of VDR mRNA]19122273
C057693troglitazonetroglitazone promotes the reaction [BMP2 protein affects the expression of PPARG mRNA]19122273
C057693troglitazonetroglitazone promotes the reaction [BMP2 protein results in decreased expression of PTH1R mRNA]19122273
C057693troglitazonetroglitazone promotes the reaction [BMP2 protein results in decreased expression of SPP1 mRNA]19122273
C057693troglitazonetroglitazone results in decreased susceptibility to BMP2 protein19122273
D014415TunicamycinTunicamycin results in increased expression of BMP2 mRNA17127020
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of BMP2 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of BMP2 mRNA23179753|2915479
D014635Valproic AcidValproic Acid results in decreased methylation of BMP2 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of BMP2 mRNA26272509
D014635Valproic AcidValproic Acid results in increased expression of BMP2 mRNA27237783
D014635Valproic AcidValproic Acid results in increased expression of BMP2 mRNA23562654
D014635Valproic AcidValproic Acid results in increased expression of BMP2 protein23562654
C066075vanadium pentoxidevanadium pentoxide affects the expression of BMP2 mRNA17459161
D001335Vehicle EmissionsBMP2 gene SNP results in increased susceptibility to Vehicle Emissions27082954
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of BMP2 gene25560391
D014750VincristineVincristine results in increased expression of BMP2 mRNA23649840
D014800Vitallium[Vitallium analog binds to titanium dioxide] which results in decreased expression of BMP2 mRNA23825117
D002762CholecalciferolBMP2 protein promotes the reaction [Cholecalciferol results in increased expression of CTNNB1 mRNA]17170073
D002762CholecalciferolCholecalciferol results in increased expression of BMP2 mRNA17170073
D010837Vitamin K 1Losartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 mRNA]27412937
D010837Vitamin K 1Losartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 protein]27412937
D010837Vitamin K 1[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 mRNA27412937
D010837Vitamin K 1[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 protein27412937
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP2 mRNA"27188386
C111237vorinostatvorinostat results in increased expression of BMP2 mRNA26272509
D014859WarfarinWarfarin inhibits the reaction [BMP2 protein results in increased activity of ALPL protein]21910061
D014859WarfarinWarfarin inhibits the reaction [BMP2 protein results in increased activity of BGLAP protein]21910061
D014859WarfarinWarfarin inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein]21910061
D014859WarfarinWarfarin inhibits the reaction [BMP2 protein results in increased expression of ALPL mRNA]21910061
D014859WarfarinWarfarin inhibits the reaction [BMP2 protein results in increased expression of BGLAP mRNA]21910061
D014859WarfarinWarfarin inhibits the reaction [BMP2 protein results in increased expression of COL1A1 mRNA]21910061
D014859WarfarinWarfarin inhibits the reaction [BMP2 protein results in increased expression of SP7 mRNA]21910061
D014859WarfarinLosartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 mRNA]27412937
D014859WarfarinLosartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 protein]27412937
D014859Warfarin[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 mRNA27412937
D014859Warfarin[Warfarin co-treated with Vitamin K 1] affects the expression of BMP2 protein27412937
C108830Y 27632Y 27632 results in increased expression of BMP2 mRNA17279577
C088658zoledronic acidzoledronic acid results in increased expression of BMP2 mRNA14751568|2471476

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004745retinol dehydrogenase activity-ISS-  
GO:0005102signaling receptor binding-TAS2315314  
GO:0005125cytokine activity-IBA21873635  
GO:0005160transforming growth factor beta receptor binding-IBA21873635  
GO:0005160transforming growth factor beta receptor binding-TAS-  
GO:0005515protein binding-IPI8413626  8752214  10881198  15064755  16672363  17240342  
18184661  18335997  18339631  19229295  19804412  20505824  
20860622  21054789  25938661  
GO:0008083growth factor activity-IEA-  
GO:0019211phosphatase activator activity-IDA9213002  
GO:0039706co-receptor binding-IPI16604073  18335997  
GO:0046332SMAD binding-IDA18184661  
GO:0046982protein heterodimerization activity-IDA7811286  
GO:0070700BMP receptor binding-IBA21873635  
GO:0070700BMP receptor binding-IDA7811286  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IBA21873635  
GO:0000122negative regulation of transcription by RNA polymerase II-IDA9187146  19736317  
GO:0000187activation of MAPK activity-IDA17202865  22540193  
GO:0001501skeletal system development-TAS2315314  
GO:0001649osteoblast differentiation-IDA15150273  22705305  
GO:0001658branching involved in ureteric bud morphogenesis-ISS-  
GO:0001666response to hypoxia-ISS-  
GO:0001701in utero embryonic development-ISS-  
GO:0001837epithelial to mesenchymal transition-IDA15110716  18184661  
GO:0001934positive regulation of protein phosphorylation-IDA8653785  17472960  
GO:0001938positive regulation of endothelial cell proliferation-IDA17992660  
GO:0002062chondrocyte differentiation-IDA16194878  
GO:0003130BMP signaling pathway involved in heart induction-IDA19736317  
GO:0003181atrioventricular valve morphogenesis-ISS-  
GO:0003203endocardial cushion morphogenesis-ISS-  
GO:0003308negative regulation of Wnt signaling pathway involved in heart development-IDA18545679  
GO:0006029proteoglycan metabolic process-IEA-  
GO:0006355regulation of transcription, DNA-templated-IDA15671031  
GO:0006468protein phosphorylation-IDA22540193  
GO:0006954inflammatory response-ISS-  
GO:0007219Notch signaling pathway-ISS-  
GO:0007267cell-cell signaling-TAS2315314  
GO:0007507heart development-ISS-  
GO:0008285negative regulation of cell proliferation-IDA9187146  19584291  
GO:0009887animal organ morphogenesis-ISS-  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0010628positive regulation of gene expression-IDA16243309  28124060  
GO:0010628positive regulation of gene expression-IGI22450430  
GO:0010629negative regulation of gene expression-IDA28124060  
GO:0010718positive regulation of epithelial to mesenchymal transition-IDA20890042  
GO:0010862positive regulation of pathway-restricted SMAD protein phosphorylation-IBA21873635  
GO:0010862positive regulation of pathway-restricted SMAD protein phosphorylation-IDA16049014  17244894  
GO:0010862positive regulation of pathway-restricted SMAD protein phosphorylation-IMP17992660  19664780  
GO:0010894negative regulation of steroid biosynthetic process-IDA19584291  
GO:0010922positive regulation of phosphatase activity-IDA9213002  
GO:0021537telencephalon development-IDA9187146  
GO:0021978telencephalon regionalization-ISS-  
GO:0030177positive regulation of Wnt signaling pathway-ISS-  
GO:0030282bone mineralization-ISS-  
GO:0030335positive regulation of cell migration-ISS-  
GO:0030501positive regulation of bone mineralization-IDA18436533  20576608  
GO:0030509BMP signaling pathway-IBA21873635  
GO:0030509BMP signaling pathway-IDA16049014  18436533  20843790  
GO:0030509BMP signaling pathway-IEP16194878  
GO:0030509BMP signaling pathway-IGI22450430  
GO:0030509BMP signaling pathway-IMP17472960  18326817  19664780  
GO:0030509BMP signaling pathway-TAS-  
GO:0031648protein destabilization-IEA-  
GO:0032092positive regulation of protein binding-IDA16604073  
GO:0032348negative regulation of aldosterone biosynthetic process-IDA19584291  
GO:0033690positive regulation of osteoblast proliferation-ISS-  
GO:0035051cardiocyte differentiation-IDA15110716  
GO:0035051cardiocyte differentiation-IMP19736317  
GO:0035054embryonic heart tube anterior/posterior pattern specification-ISS-  
GO:0035630bone mineralization involved in bone maturation-IDA16433617  
GO:0042475odontogenesis of dentin-containing tooth-ISS-  
GO:0042482positive regulation of odontogenesis-ISS-  
GO:0042487regulation of odontogenesis of dentin-containing tooth-IEA-  
GO:0042981regulation of apoptotic process-IBA21873635  
GO:0043065positive regulation of apoptotic process-IDA9187146  
GO:0043408regulation of MAPK cascade-IBA21873635  
GO:0043410positive regulation of MAPK cascade-IDA22540193  
GO:0043569negative regulation of insulin-like growth factor receptor signaling pathway-IDA19584291  
GO:0045165cell fate commitment-ISS-  
GO:0045600positive regulation of fat cell differentiation-ISS-  
GO:0045666positive regulation of neuron differentiation-ISS-  
GO:0045669positive regulation of osteoblast differentiation-IDA15254224  16433617  18436533  20576608  
GO:0045778positive regulation of ossification-IDA9213002  
GO:0045786negative regulation of cell cycle-IDA11502704  
GO:0045892negative regulation of transcription, DNA-templated-IDA15254224  
GO:0045893positive regulation of transcription, DNA-templated-IDA16049014  16243309  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA9187146  16433617  16604073  19736317  20890042  
GO:0045944positive regulation of transcription by RNA polymerase II-IGI18326817  
GO:0048468cell development-IBA21873635  
GO:0048711positive regulation of astrocyte differentiation-ISS-  
GO:0048762mesenchymal cell differentiation-IDA9693150  
GO:0048839inner ear development-ISS-  
GO:0051042negative regulation of calcium-independent cell-cell adhesion-IDA16194878  
GO:0055007cardiac muscle cell differentiation-IMP21311046  
GO:0055008cardiac muscle tissue morphogenesis-ISS-  
GO:0055114oxidation-reduction process-IEA-  
GO:0060039pericardium development-ISS-  
GO:0060128corticotropin hormone secreting cell differentiation-ISS-  
GO:0060129thyroid-stimulating hormone-secreting cell differentiation-ISS-  
GO:0060317cardiac epithelial to mesenchymal transition-IDA18184661  
GO:0060389pathway-restricted SMAD protein phosphorylation-IDA16049014  18184661  
GO:0060395SMAD protein signal transduction-IBA21873635  
GO:0060395SMAD protein signal transduction-IDA17244894  
GO:0060485mesenchyme development-IMP20890042  
GO:0060804positive regulation of Wnt signaling pathway by BMP signaling pathway-ISS-  
GO:0061036positive regulation of cartilage development-IDA3201241  
GO:0070374positive regulation of ERK1 and ERK2 cascade-IDA22540193  
GO:0070374positive regulation of ERK1 and ERK2 cascade-IMP19664780  
GO:0071407cellular response to organic cyclic compound-IEA-  
GO:0071773cellular response to BMP stimulus-IDA20843790  
GO:0071773cellular response to BMP stimulus-IMP18326817  
GO:0072138mesenchymal cell proliferation involved in ureteric bud development-ISS-  
GO:0090090negative regulation of canonical Wnt signaling pathway-IEP17202865  
GO:1900745positive regulation of p38MAPK cascade-IDA22540193  
GO:1901522positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-IDA20843790  
GO:1902895positive regulation of pri-miRNA transcription by RNA polymerase II-IEA-  
GO:2000065negative regulation of cortisol biosynthetic process-IDA19584291  
GO:2000726negative regulation of cardiac muscle cell differentiation-IDA18545679  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IBA21873635  
GO:0005615extracellular space-IDA16604073  
GO:0009986cell surface-IDA22227436  
GO:0043231intracellular membrane-bounded organelle-IDA-  
GO:0070724BMP receptor complex-IDA16604073  
KEGG ID KEGG Term
hsa04060Cytokine-cytokine receptor interaction
hsa04340Hedgehog signaling pathway
hsa04350TGF-beta signaling pathway
hsa05200Pathways in cancer
hsa05217Basal cell carcinoma
Reactome ID Reactome Term Evidence
R-HSA-1474244Extracellular matrix organizationTAS
R-HSA-1566948Elastic fibre formationTAS
R-HSA-162582Signal TransductionTAS
R-HSA-201451Signaling by BMPTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-212436Generic Transcription PathwayIEA
R-HSA-2129379Molecules associated with elastic fibresTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-73857RNA Polymerase II TranscriptionIEA
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-74160Gene expression (Transcription)IEA
R-HSA-8878166Transcriptional regulation by RUNX2TAS
R-HSA-8878166Transcriptional regulation by RUNX2IEA
R-HSA-8939902Regulation of RUNX2 expression and activityIEA
R-HSA-9006936Signaling by TGF-beta family membersTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
12958694Semiquantitative mRNA measurements of osteoinductive growth factors in human iliac-crest bone: expression of LMP splice variants in human bone. (2003 Nov)Bunger MHCalcif Tissue Int
24205156Heterodimeric BMP-2/7 antagonizes the inhibition of all-trans retinoic acid and promotes the osteoblastogenesis. (2013)Bi WPLoS One
19662102The Epithelial Cell in Lung Health and Emphysema Pathogenesis. (2006 May)Mercer BACurr Respir Med Rev
25591783Cigarette smoking hinders human periodontal ligament-derived stem cell proliferation, migration and differentiation potentials. (2015 Jan 16)Ng TKSci Rep
19345526[Origin of the mediacalcosis in kidney failure]. (2009 May)Torres PAJ Mal Vasc
22367214Characterization of gene-environment interactions for colorectal cancer susceptibility loci. (2012 Apr 15)Hutter CMCancer Res