Gene: SMARCA2

6595
BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
protein-coding
9p24.3
Ensembl:ENSG00000080503 MIM:600014 Vega:OTTHUMG00000019445 UniprotKB:P51531
NG_032162.2
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.094e-1 (AD)  5.713e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DCAF110.945
PFKM0.936
PBX10.934
ARNT20.933
SPTAN10.931
SNN0.928
ACSL30.927
CKAP50.926
ABI20.926
APLP20.924

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.71
OR4F29-0.679
TFPI2-0.369
GNG8-0.361
BEST3-0.356
SPINK8-0.345
PPBP-0.341
SGMS2-0.339
SLAMF6-0.339
CST7-0.337

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of SMARCA2 mRNA"26377693
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of SMARCA2 mRNA"19114083
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of SMARCA2 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in increased expression of SMARCA2 mRNA"20406850
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of SMARCA2 mRNA]"19467301
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C0352074-amino-2,6-dinitrotoluene"4-amino-2,6-dinitrotoluene affects the expression of SMARCA2 mRNA"21346803
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of SMARCA2 mRNA21420995
D000082AcetaminophenAcetaminophen results in increased expression of SMARCA2 mRNA22230336
D000082AcetaminophenAcetaminophen affects the expression of SMARCA2 mRNA17562736
D020106AcrylamideAcrylamide results in decreased expression of SMARCA2 mRNA28959563
D013196DihydrotestosteroneDihydrotestosterone promotes the reaction [AR protein binds to SMARCA2 protein]18487222
D013196DihydrotestosteroneDihydrotestosterone promotes the reaction [SMARCA2 protein binds to KLK3 promoter]18487222
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of SMARCA2 mRNA21298039
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of SMARCA2 mRNA24449571
C006632arsenic trioxidearsenic trioxide results in increased expression of SMARCA2 mRNA20458559
D001280AtrazineAtrazine results in decreased expression of SMARCA2 mRNA25929836
C487081belinostatbelinostat results in increased expression of SMARCA2 mRNA26272509
C487081belinostat"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of SMARCA2 mRNA20106945|2163298
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SMARCA2 mRNA20504355
C543008bis(4-hydroxyphenyl)sulfone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SMARCA2 mRNA28628672
C006780bisphenol Abisphenol A results in decreased expression of SMARCA2 mRNA26364221
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SMARCA2 mRNA28628672
C006780bisphenol Abisphenol A affects the expression of SMARCA2 mRNA25181051
C006780bisphenol A[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of SMARCA2 promoter23359474
C006780bisphenol Abisphenol A results in increased methylation of SMARCA2 gene28505145
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SMARCA2 mRNA28628672
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of SMARCA2 mRNA15336504
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of SMARCA2 mRNA18560533
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in increased expression of SMARCA2 mRNA26272509
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SMARCA2 mRNA20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of SMARCA220938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SMARCA2 gene20938992
D002994ClofibrateClofibrate results in decreased expression of SMARCA2 mRNA16081524
D003042CocaineCocaine results in increased expression of SMARCA2 mRNA17898221
D003300Copper[Thiosemicarbazones binds to Copper] which results in increased expression of SMARCA2 protein20931265
D019327Copper SulfateCopper Sulfate results in increased expression of SMARCA2 mRNA19549813
D016572CyclosporineCyclosporine results in decreased expression of SMARCA2 mRNA25562108
D016572CyclosporineCyclosporine results in decreased expression of SMARCA2 mRNA19770486
D016572CyclosporineCyclosporine results in decreased expression of SMARCA2 mRNA21865292
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of SMARCA2 mRNA23640034
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of SMARCA2 mRNA]27941970
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SMARCA2 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SMARCA2 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SMARCA2 mRNA28628672
D003993Dibutyl Phthalate[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of SMARCA2 promoter23359474
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of SMARCA2 mRNA]"19467301
D004041Dietary FatsDietary Fats results in increased expression of SMARCA2 mRNA19030233|1946730
D004041Dietary Fatsrimonabant inhibits the reaction [Dietary Fats results in increased expression of SMARCA2 mRNA]19030233
D004051Diethylhexyl Phthalate[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of SMARCA2 promoter23359474
D011397PromegestoneSMARCA2 protein affects the reaction [Promegestone results in increased expression of FOS mRNA]19609353
D011397PromegestoneSMARCA2 protein affects the reaction [Promegestone results in increased expression of MYC mRNA]19609353
C118739entinostatentinostat results in increased expression of SMARCA2 mRNA26272509|2718838
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SMARCA2 mRNA22079256
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of SMARCA2 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SMARCA2 mRNA17942748
D005485FlutamideFlutamide results in decreased expression of SMARCA2 mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SMARCA2 mRNA20938992
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of SMARCA220938992
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SMARCA2 gene20938992
C001277geldanamycingeldanamycin results in increased expression of SMARCA2 mRNA26705709
D019833GenisteinGenistein affects the expression of SMARCA2 mRNA18214933
D005897GlafenineGlafenine results in decreased expression of SMARCA2 mRNA24136188
C029424hydrazinehydrazine results in increased expression of SMARCA2 mRNA15282401
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SMARCA2 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SMARCA2 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SMARCA2 mRNA28628672
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SMARCA2 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SMARCA2 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SMARCA2 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SMARCA2 mRNA28628672
D007854LeadLead affects the expression of SMARCA2 mRNA28903495
C042720mercuric bromidemercuric bromide results in increased expression of SMARCA2 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SMARCA2 mRNA20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of and results in decreased expression of SMARCA220938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SMARCA2 gene20938992
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of SMARCA2 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of SMARCA2 mRNA26011545
C523799MRK 003MRK 003 results in decreased expression of SMARCA2 mRNA21169257
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of SMARCA2 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of SMARCA2 mRNA"25554681|2562005
D009532NickelNickel results in decreased expression of SMARCA2 mRNA25583101
D009532NickelNickel results in decreased expression of SMARCA2 mRNA24084258
C029938nickel sulfatenickel sulfate results in decreased expression of SMARCA2 mRNA22714537
D010100OxygenOxygen deficiency results in increased expression of SMARCA2 mRNA24205000
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of SMARCA2 mRNA26272509
D010416PentachlorophenolPentachlorophenol results in increased expression of SMARCA2 mRNA24642059
D010634PhenobarbitalPhenobarbital affects the expression of SMARCA2 mRNA23091169
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of SMARCA2 mRNA26272509
C006253pirinixic acidpirinixic acid results in decreased expression of SMARCA2 mRNA18445702|2381119
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SMARCA2 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of SMARCA2 mRNA22079256
C089032rimonabantrimonabant inhibits the reaction [Dietary Fats results in increased expression of SMARCA2 mRNA]19030233
C513635S-2-pentyl-4-pentynoic hydroxamic acidS-2-pentyl-4-pentynoic hydroxamic acid results in increased expression of SMARCA2 mRNA21427059
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of SMARCA2 mRNA25895662
C017947sodium arsenitesodium arsenite affects the expression of SMARCA2 mRNA29319823
C016104sodium bichromatesodium bichromate results in decreased expression of SMARCA2 mRNA25993096
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SMARCA2 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SMARCA2 mRNA15328365|1977048
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SMARCA2 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SMARCA2 mRNA21215274
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SMARCA2 mRNA25613284
D013882Thiosemicarbazones[Thiosemicarbazones binds to Copper] which results in increased expression of SMARCA2 protein20931265
C009495titanium dioxidetitanium dioxide results in decreased expression of SMARCA2 mRNA27760801
C009495titanium dioxidetitanium dioxide results in increased expression of SMARCA2 mRNA23557971
D014212TretinoinTretinoin results in increased expression of SMARCA2 mRNA17218384|2193413
D014212TretinoinTretinoin results in increased expression of SMARCA2 mRNA16604517
D014241TrichloroethyleneTrichloroethylene results in increased methylation of SMARCA2 gene27618143
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of SMARCA2 mRNA24935251|2627250
D014520UrethaneUrethane results in increased expression of SMARCA2 mRNA28818685
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of SMARCA2 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of SMARCA2 mRNA19101580|2317975
D014635Valproic AcidValproic Acid results in increased expression of SMARCA2 mRNA21427059
D001335Vehicle EmissionsVehicle Emissions affects the methylation of SMARCA2 gene25560391
C025643vinclozolinvinclozolin affects the expression of SMARCA2 mRNA19015723
C025643vinclozolinvinclozolin results in increased expression of SMARCA2 mRNA18042343
C111237vorinostatvorinostat results in increased expression of SMARCA2 mRNA27188386

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003682chromatin binding-IEA-  
GO:0003713transcription coactivator activity-IDA17984088  
GO:0004386helicase activity-IEA-  
GO:0005515protein binding-IPI12065415  12200431  15107404  15696166  16341228  16601680  
17984088  20111005  25910212  26787460  
GO:0005524ATP binding-IEA-  
GO:0008094DNA-dependent ATPase activity-TAS17938176  
GO:0042393histone binding-IEA-  
GO:0044212transcription regulatory region DNA binding-IDA17984088  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-TAS17938176  
GO:0006338chromatin remodelingNOTIMP22368283  
GO:0006338chromatin remodeling-TAS17938176  
GO:0006351transcription, DNA-templated-IEA-  
GO:0006355regulation of transcription, DNA-templated-TAS8670841  
GO:0006357regulation of transcription by RNA polymerase II-TAS8223438  
GO:0007286spermatid development-IEA-  
GO:0007399nervous system development-IEA-  
GO:0008285negative regulation of cell proliferation-IDA14660596  
GO:0030308negative regulation of cell growth-IMP12065415  
GO:0045892negative regulation of transcription, DNA-templated-IDA12065415  
GO:0045893positive regulation of transcription, DNA-templated-IDA17984088  
GO:0045893positive regulation of transcription, DNA-templated-IMP8208605  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA15774904  
GO:0045944positive regulation of transcription by RNA polymerase II-TAS17938176  
GO ID GO Term Qualifier Evidence PubMed
GO:0000790nuclear chromatin-IDA12065415  
GO:0005634nucleus-IDA17984088  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0016514SWI/SNF complex-IDA11078522  
GO:0043231intracellular membrane-bounded organelle-IDA-  
GO:0045111intermediate filament cytoskeleton-IDA-  
GO:0071564npBAF complex-ISS-  
GO:0071565nBAF complex-ISS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-3214858RMTs methylate histone argininesTAS
R-HSA-3247509Chromatin modifying enzymesTAS
R-HSA-4839726Chromatin organizationTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8878171Transcriptional regulation by RUNX1TAS
R-HSA-8939243RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not knownTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28256572Clinicopathological and molecular characterization of SMARCA4-deficient thoracic sarcomas with comparison to potentially related entities. (2017 Jun)Yoshida AMod Pathol