Gene: SRC

6714
ASV|SRC1|THC6|c-SRC|p60-Src
SRC proto-oncogene, non-receptor tyrosine kinase
protein-coding
20q11.23
Ensembl:ENSG00000197122 MIM:190090 Vega:OTTHUMG00000032417 UniprotKB:P12931
NG_023033.1
PubMed
CD|OD|ND|AD
50   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.452e-1 (AD)  8.278e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FBXO310.922
PI4K2A0.921
ZNF7460.921
UBE2O0.917
MBOAT70.916
MARK20.916
PITPNM20.916
SLC25A420.915
PGAM50.915
ZNF3240.915

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.554
CTNNA3-0.502
OR4F29-0.501
LRRCC1-0.441
SH2D1A-0.439
SEPT10-0.437
MBNL3-0.436
C5orf64-0.429
NEK7-0.415
SLCO1A2-0.415

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01254DasatinibSmall Molecule302962-49-8Approved|InvestigationalTarget
DB01678RU84687Small MoleculeExperimentalTarget
DB01866RU79256Small Molecule-ExperimentalTarget
DB01893N6-Benzyl Adenosine-5'-DiphosphateSmall MoleculeExperimentalTarget
DB01908RU85493Small MoleculeExperimentalTarget
DB01947RU78262Small MoleculeExperimentalTarget
DB01962PhosphonotyrosineSmall Molecule21820-51-9ExperimentalTarget
DB02175Malonic acidSmall Molecule141-82-2ExperimentalTarget
DB02336RU83876Small MoleculeExperimentalTarget
DB02432RU90395Small MoleculeExperimentalTarget
DB02762RU79072Small MoleculeExperimentalTarget
DB02908RU78783Small MoleculeExperimentalTarget
DB030231-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-YlamineSmall MoleculeExperimentalTarget
DB03078PASBNSmall Molecule-ExperimentalTarget
DB03104RU82129Small MoleculeExperimentalTarget
DB03114PAS219Small MoleculeExperimentalTarget
DB03217DPI59Small MoleculeExperimentalTarget
DB03268RU82197Small MoleculeExperimentalTarget
DB03298PhenylphosphateSmall MoleculeExperimentalTarget
DB03306RU78300Small MoleculeExperimentalTarget
DB03525RU79073Small MoleculeExperimentalTarget
DB03591RU82209Small MoleculeExperimentalTarget
DB03628ISO24Small MoleculeExperimentalTarget
DB03712RU85053Small MoleculeExperimentalTarget
DB03828RU78299Small MoleculeExperimentalTarget
DB03902Oxalic AcidSmall Molecule144-62-7ExperimentalTarget
DB04080RU78191Small MoleculeExperimentalTarget
DB04272Citric AcidSmall Molecule77-92-9Approved|NutraceuticalTarget
DB04495RU81843Small MoleculeExperimentalTarget
DB047394-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDESmall MoleculeExperimentalTarget
DB04751Purvalanol ASmall Molecule212844-53-6ExperimentalTarget
DB05184XL228Small Molecule-InvestigationalTarget
DB06137KX-01Small Molecule897016-82-9InvestigationalTarget
DB06616BosutinibSmall Molecule380843-75-4ApprovedTarget
DB068821-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylureaSmall MoleculeExperimentalTarget
DB068831-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylureaSmall MoleculeExperimentalTarget
DB073353-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOLSmall MoleculeExperimentalTarget
DB07662N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDESmall MoleculeExperimentalTarget
DB07966[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrileSmall MoleculeExperimentalTarget
DB080521-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amineSmall MoleculeExperimentalTarget
DB080531-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amineSmall MoleculeExperimentalTarget
DB080541-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amineSmall MoleculeExperimentalTarget
DB081922-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINESmall MoleculeExperimentalTarget
DB08462N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDESmall MoleculeExperimentalTarget
DB08564(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamideSmall MoleculeExperimentalTarget
DB08901PonatinibSmall Molecule943319-70-8Approved|InvestigationalTarget
DB09079NintedanibSmall Molecule656247-17-5ApprovedTarget
ID Drug Name Action PubMed
C4350441-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol inhibits the reaction [IL1B protein results in increased phosphorylation of SRC protein]22936809
C0468391,2,3,4,6,7,8-heptachlorodibenzodioxin"1,2,3,4,6,7,8-heptachlorodibenzodioxin results in increased localization of SRC protein"10401681
C0514521,2,3,7,8-pentachlorodibenzo-p-dioxin"1,2,3,7,8-pentachlorodibenzo-p-dioxin results in increased activity of SRC protein"8937476
C0389831,3-dimethylthiourea"1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of SRC protein]"21575692
C0602291-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [IL1B protein results in increased phosphorylation of SRC protein]"19281832
C4001841-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased phosphorylation of SRC protein24079413
C4001841-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholineresveratrol inhibits the reaction [1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased phosphorylation of SRC protein]24079413
C4172072,2',4,6,6'-pentachlorobiphenyl"2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of SRC protein"16611624
C4172072,2',4,6,6'-pentachlorobiphenyl"SRC protein promotes the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased expression of CXCL8 mRNA]"16611624
C4172072,2',4,6,6'-pentachlorobiphenyl"SRC protein promotes the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of AKT1 protein]"16611624
C4172072,2',4,6,6'-pentachlorobiphenyl"SRC protein promotes the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of MAPK1 protein]"16611624
C4172072,2',4,6,6'-pentachlorobiphenyl"SRC protein promotes the reaction [2,2',4,6,6'-pentachlorobiphenyl results in increased phosphorylation of MAPK3 protein]"16611624
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]19782052
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Thyroxine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of SRC protein"19632255
C0140242,4,5,2',4',5'-hexachlorobiphenyl"Filipin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of SRC protein]"19632255
C0140242,4,5,2',4',5'-hexachlorobiphenyl"methyl-beta-cyclodextrin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of SRC protein]"19632255
C07699627-hydroxycholesterol27-hydroxycholesterol results in decreased activity of SRC protein18503570
C0127292-amino-4-phosphonobutyric acid2-amino-4-phosphonobutyric acid affects the activity of SRC protein16624952
C5724913-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol results in increased expression of SRC protein26194647
C4824923,4,5,4'-tetramethoxystilbene"3,4,5,4'-tetramethoxystilbene results in decreased phosphorylation of SRC protein"23770989
C5240423,5-bis(2-fluorobenzylidene)piperidin-4-one"3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased phosphorylation of SRC protein"25725129
C5240423,5-bis(2-fluorobenzylidene)piperidin-4-one"MIR33B mRNA affects the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased phosphorylation of SRC protein]"25725129
C0414773-hydroxyflavone3-hydroxyflavone results in decreased phosphorylation of SRC protein27600294
C0917683'-methoxy-4'-nitroflavone3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]21145940
C0917683'-methoxy-4'-nitroflavone3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]19782052
C0020104-(2-aminoethyl)benzenesulfonylfluoride4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of SRC protein]23376140
C0006020014-(3,5-dimethoxystyryl)phenyl acetate"4-(3,5-dimethoxystyryl)phenyl acetate results in increased phosphorylation of SRC protein"26138072
C0888604-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead acetate results in increased phosphorylation of SRC protein]"19133285
C575425(4-(4'-chloro-2'-fluoro)phenylamino)-6,7-dimethylquinazoline"(4-(4'-chloro-2'-fluoro)phenylamino)-6,7-dimethylquinazoline results in decreased activity of SRC protein"22573732
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SRC mRNA"27188386
C5688624-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline"4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Dehydroepiandrosterone results in increased phosphorylation of SRC protein]"25969534
C5550214-acetylantroquinonol B4-acetylantroquinonol B results in decreased phosphorylation of SRC protein26235807
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [EGF protein results in increased phosphorylation of SRC protein]"25856345
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [IL1B protein results in increased phosphorylation of SRC protein]"19281832
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to NCF1 protein]]"19608869
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine results in decreased phosphorylation of SRC protein"25856345
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Cisplatin promotes the reaction [SRC protein binds to PRKCD protein]]"21633170
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [TNF protein results in increased phosphorylation of SRC protein]"19608869
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Oxygen deficiency results in increased phosphorylation of SRC protein]"15913578
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of SRC protein]"17116659
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of SRC protein]"19233221
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine results in decreased activity of SRC protein"15592923
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [IL1B protein results in increased phosphorylation of SRC protein]"22936809
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine results in decreased activity of SRC protein"22936809
C0138134-anisidine4-anisidine results in increased expression of SRC mRNA12929121
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of SRC mRNA19191707
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SRC mRNA"27188386
C4750936-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime"6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [SRC protein binds to NR1I3 protein]"24224465
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein]"16510265
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [ARRB1 protein modified form binds to SRC protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to IL1R1 protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to TNFRSF1A protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [EGFR protein modified form binds to SRC protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [PTGER2 protein binds to SRC protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [PTGER4 protein binds to SRC protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of SRC protein19407222
D000082AcetaminophenAcetaminophen affects the expression of SRC mRNA16701773
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased phosphorylation of SRC protein]21777978
D000111AcetylcysteineAcetylcysteine inhibits the reaction [VEGFA protein results in increased activity of SRC protein]14573751
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of SRC mRNA22100608
C412373AG 1879[AG 1879 co-treated with SRC] results in increased susceptibility to gemcitabine15073106
C412373AG 1879AG 1879 inhibits the reaction [bisphenol A results in increased phosphorylation of SRC protein]18544561
C412373AG 1879AG 1879 inhibits the reaction [CDKN1B protein binds to SRC protein]28215542
C412373AG 1879AG 1879 inhibits the reaction [[cobaltous chloride results in increased activity of SRC protein] which results in increased expression of HIF1A protein]15735682
C412373AG 1879AG 1879 inhibits the reaction [[cobaltous chloride results in increased activity of SRC protein] which results in increased phosphorylation of STAT3 protein]15735682
C412373AG 1879AG 1879 inhibits the reaction [cobaltous chloride results in increased phosphorylation of and results in increased activity of SRC protein]15735682
C412373AG 1879AG 1879 inhibits the reaction [EGF protein results in increased phosphorylation of SRC protein]21145940
C412373AG 1879AG 1879 inhibits the reaction [Estradiol results in increased phosphorylation of SRC protein]18544561
C412373AG 1879AG 1879 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of SRC protein]25980585
C412373AG 1879AG 1879 inhibits the reaction [Oxygen deficiency results in increased phosphorylation of and results in increased activity of SRC protein]17671207
C412373AG 1879AG 1879 inhibits the reaction [resveratrol results in increased phosphorylation of SRC protein]17513867
C412373AG 1879AG 1879 inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]21145940
C412373AG 1879AG 1879 results in decreased activity of SRC protein17186241|2707194
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [amurensin G results in increased phosphorylation of NOS3 protein]22982565
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein]23673518
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein]23673518
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased activity of and results in increased phosphorylation of NOS3 protein]21300668
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK1 protein]21300668
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK3 protein]21300668
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein]21205633
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of STAT5B protein]21205633
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [monomethylarsonous acid results in increased expression of PTGS2 protein]17093206
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]15213856
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] which affects the localization of ESR1 protein19815064
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] which results in decreased susceptibility to Hexachlorobenzene21205633
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] which results in decreased susceptibility to TNF protein18606683
C412373AG 1879AG 1879 results in decreased phosphorylation of and results in decreased activity of SRC protein19151764
C412373AG 1879AG 1879 results in decreased phosphorylation of SRC protein17186241
C412373AG 1879AG 1879 inhibits the reaction [Cisplatin promotes the reaction [SRC protein binds to PRKCD protein]]21633170
C412373AG 1879AG 1879 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of SRC protein]23735482
C412373AG 1879AG 1879 inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]19782052
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Indican results in increased phosphorylation of SRC protein]23639249
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Indican results in increased phosphorylation of STAT3 protein]23639249
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]23639249
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of STAT3 protein]23639249
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] which results in decreased susceptibility to Tetrachlorodibenzodioxin23639249
C412373AG 1879AG 1879 inhibits the reaction [Capsaicin results in increased activity of SRC protein]21340460
C412373AG 1879AG 1879 inhibits the reaction [SRC protein promotes the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein]]18295415
C412373AG 1879AG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of SRC protein]12211081
C412373AG 1879AG 1879 results in decreased activity of SRC protein15574683|1829541
C412373AG 1879AG 1879 inhibits the reaction [Thyroxine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
C412373AG 1879AG 1879 inhibits the reaction [Triiodothyronine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
C412373AG 1879AG 1879 results in decreased activity of SRC protein14569062|1521385
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [ARRB1 protein modified form binds to SRC protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to IL1R1 protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to TNFRSF1A protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [EGFR protein modified form binds to SRC protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [PTGER2 protein binds to SRC protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [PTGER4 protein binds to SRC protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of SRC protein19407222
C004471allyl isothiocyanateallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]25069801
C004471allyl isothiocyanateallyl isothiocyanate inhibits the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]25069801
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased phosphorylation of SRC protein"20197088
D013196DihydrotestosteroneDihydrotestosterone promotes the reaction [AR protein binds to SRC protein binds to PELP1 protein]15466214
D013196DihydrotestosteroneDihydrotestosterone results in increased activity of SRC protein15466214
D013196DihydrotestosteroneSRC protein promotes the reaction [[Dihydrotestosterone co-treated with Tetrachlorodibenzodioxin] results in increased activity of AR protein]19815066
D013196DihydrotestosteroneSRC protein promotes the reaction [Dihydrotestosterone results in increased activity of AR protein]19815066
D013196DihydrotestosteroneDihydrotestosterone inhibits the reaction [Dehydroepiandrosterone results in increased phosphorylation of SRC protein]16407456
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of SRC protein]8937476
D000641AmmoniaSRC protein affects the reaction [Ammonia results in increased expression of ATP1A2 mRNA]20447429
D000641AmmoniaSRC protein affects the reaction [Ammonia results in increased expression of ATP1A2 protein]20447429
D000643Ammonium ChlorideAmmonium Chloride affects the expression of SRC mRNA16483693
C553921amurensin G[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [amurensin G results in increased phosphorylation of NOS3 protein]22982565
C553921amurensin Gamurensin G results in increased phosphorylation of and results in increased activity of SRC protein22982565
D000880AnthraquinonesAnthraquinones analog results in decreased activity of SRC protein27473261
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of SRC mRNA24449571
D047310ApigeninApigenin results in decreased activity of SRC protein19814731
D001151ArsenicArsenic affects the methylation of SRC gene25304211
D001151ArsenicArsenic results in increased phosphorylation of and results in increased activity of SRC protein23100159
D001151ArsenicIron promotes the reaction [Arsenic results in increased phosphorylation of and results in increased activity of SRC protein]23100159
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased phosphorylation of SRC protein]21777978
C006632arsenic trioxide[arsenic trioxide co-treated with PD 173074] results in decreased expression of SRC protein27794399
C006632arsenic trioxidearsenic trioxide results in decreased expression of SRC mRNA20458559
C006632arsenic trioxidearsenic trioxide results in decreased expression of SRC protein27794399
C006632arsenic trioxidearsenic trioxide results in decreased expression of SRC protein modified form27794399
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of SRC protein18588940|2177797
C006632arsenic trioxide[arsenic trioxide results in increased susceptibility to PD 173074] which results in decreased expression of SRC protein27794399
C006632arsenic trioxidebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[arsenic trioxide co-treated with PD 173074] results in decreased expression of SRC protein]27794399
C006632arsenic trioxidePD 173074 promotes the reaction [arsenic trioxide results in decreased expression of SRC protein]27794399
C006632arsenic trioxidePD 173074 promotes the reaction [arsenic trioxide results in decreased expression of SRC protein modified form]27794399
C006632arsenic trioxide[PD 173074 results in increased susceptibility to arsenic trioxide] which results in decreased expression of SRC protein27794399
D017639Asbestos, Amosite"Asbestos, Amosite results in increased activity of SRC protein"29112861
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of SRC mRNA"23634900
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased phosphorylation of SRC protein"14737115
D017638Asbestos, Crocidolite"SRC protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]"14737115
D017638Asbestos, Crocidolite"SRC protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]"14737115
D001205Ascorbic AcidSRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]]14505802
D001205Ascorbic AcidSRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA]]14505802
D001397Azoxymethane[[Azoxymethane co-treated with Sulindac] results in increased expression of CSK protein] which results in increased phosphorylation of and results in decreased activity of SRC protein18644992
C004456beauvericinbeauvericin results in decreased activity of SRC protein25178661
C037689benzamidebenzamide analog results in decreased activity of SRC protein15186837
C032157benzamidinebenzamidine analog results in decreased activity of SRC protein15186837
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SRC mRNA18164116
D001564Benzo(a)pyreneBenzo(a)pyrene affects the splicing of SRC exon26001963
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SRC mRNA"28529061
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SRC protein"28529061
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[arsenic trioxide co-treated with PD 173074] results in decreased expression of SRC protein]27794399
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SRC protein binds to NR1I3 protein]24224465
D004958EstradiolEstradiol promotes the reaction [SRC protein binds to CAV1 protein]18296501
D004958EstradiolEstradiol promotes the reaction [SRC protein modified form binds to CAV1 protein]18296501
D004958EstradiolEstradiol promotes the reaction [SRC protein modified form binds to SRC protein]18296501
D004958Estradiolmethyl-beta-cyclodextrin inhibits the reaction [Estradiol promotes the reaction [SRC protein modified form binds to CAV1 protein]]18296501
D004958EstradiolAG 1879 inhibits the reaction [Estradiol results in increased phosphorylation of SRC protein]18544561
D004958EstradiolEstradiol results in increased activity of SRC protein15615701
D004958EstradiolEstradiol results in increased phosphorylation of and results in increased activity of SRC protein20206645
D004958EstradiolEstradiol results in increased phosphorylation of SRC protein18296501|1854456
D004958EstradiolEstradiol results in increased expression of SRC mRNA17010207
C031463beta-glycerophosphoric acidSRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]]14505802
C031463beta-glycerophosphoric acidSRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA]]14505802
C023888beta-hexachlorocyclohexanebeta-hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of SRC protein20206645
C044887beta-methylcholinebeta-methylcholine results in increased phosphorylation of SRC protein21179406
C044887beta-methylcholineHydrogen Peroxide inhibits the reaction [beta-methylcholine results in increased phosphorylation of SRC protein]21179406
C006780bisphenol Abisphenol A affects the expression of SRC mRNA21786754
C006780bisphenol AAG 1879 inhibits the reaction [bisphenol A results in increased phosphorylation of SRC protein]18544561
C006780bisphenol Abisphenol A results in decreased expression of SRC mRNA26363213
C006780bisphenol Abisphenol A results in increased phosphorylation of SRC protein18544561
C006780bisphenol ASRC inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]22227104
C006780bisphenol ASRC inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]22227104
C006780bisphenol ASRC inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]22227104
C006780bisphenol ASRC inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]22227104
C006780bisphenol Abisphenol A inhibits the reaction [Genistein results in decreased expression of SRC protein]24884420
C006780bisphenol Abisphenol A results in decreased expression of SRC protein19497385|2873953
C006780bisphenol Abisphenol A results in increased expression of SRC mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of SRC protein24884420
C006780bisphenol AGenistein inhibits the reaction [bisphenol A results in increased expression of SRC protein]24884420
C006780bisphenol Abisphenol A inhibits the reaction [Thyroxine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
C006780bisphenol Abisphenol A inhibits the reaction [Triiodothyronine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
C471992bosutinibbosutinib inhibits the reaction [SRC protein results in increased phosphorylation of CTNNB1 protein]16489032
C471992bosutinibbosutinib results in decreased phosphorylation of SRC protein16489032
C471992bosutinibbosutinib results in decreased activity of SRC protein17114238
C027561butylbenzyl phthalatebutylbenzyl phthalate results in increased phosphorylation of SRC protein22552774
C027561butylbenzyl phthalatefulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of SRC protein]22552774
D020122tert-Butylhydroperoxide"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of SRC protein]"17116659
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased phosphorylation of SRC protein17116659
D002101Cacodylic Acid[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of SRC mRNA23192986
D019256Cadmium Chloride[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein]23673518
D019256Cadmium Chloride[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein]23673518
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of SRC protein28527916
D019256Cadmium Chloride4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of SRC protein]23376140
D019256Cadmium Chloride[Cadmium Chloride co-treated with TNFSF11] results in increased expression of SRC mRNA21723911
D019256Cadmium ChlorideCadmium Chloride promotes the reaction [EGFR protein binds to SRC protein]23376140
D019256Cadmium ChlorideCadmium Chloride promotes the reaction [STAT3 protein binds to SRC protein]23376140
D019256Cadmium Chloride[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein23376140
D019256Cadmium Chloride[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein23376140
D019256Cadmium Chloride[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein23376140
D019256Cadmium Chloride[[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein] promotes the reaction [STAT3 protein binds to STAT3 protein]23376140
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of and results in increased activity of SRC protein23376140
D019256Cadmium Chloride[SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased expression of MT2 protein]23376140
D019256Cadmium Chloride[SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of EGFR protein]23376140
D019256Cadmium Chloride[SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]23376140
D019256Cadmium Chloride[SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]23376140
D019256Cadmium Chloride[[tyrphostin AG 1478 results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]23376140
D019256Cadmium Chloride"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of SRC protein]"19233221
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of SRC protein19233221
D019256Cadmium ChlorideKN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of SRC protein]19233221
D019256Cadmium ChlorideCAT protein inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of SRC protein]23376140
D000001CalcimycinCalcimycin results in increased phosphorylation of SRC protein19782052
D002118CalciumCalcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]19782052
D002118CalciumSRC protein affects the susceptibility to Calcium17551092
D002118CalciumSRC protein affects the transport of Calcium17551092
D002211CapsaicinCapsaicin results in decreased phosphorylation of and results in decreased activity of SRC protein17505005
D002211CapsaicinSRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]20660715
D002211CapsaicinAG 1879 inhibits the reaction [Capsaicin results in increased activity of SRC protein]21340460
D002211CapsaicinCapsaicin results in increased activity of SRC protein21340460
D002217CarbacholCarbachol results in increased phosphorylation of and results in increased activity of SRC protein16877402
D002217CarbacholSRC protein affects the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK1 protein]16877402
D002217CarbacholSRC protein affects the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK3 protein]16877402
D002217CarbacholSRC protein affects the reaction [Carbachol results in increased phosphorylation of and results in increased activity of PTK2B protein]16877402
D002220CarbamazepineCarbamazepine affects the expression of SRC mRNA24752500
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of SRC mRNA15056808
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of SRC mRNA12734012
C119957CGP 77675[CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]15213856
C119957CGP 77675CGP 77675 results in decreased activity of SRC protein15213856
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SRC mRNA20938992
D017608Chromium CompoundsChromium Compounds results in increased activity of SRC protein19406221
C074702chromium hexavalent ionchromium hexavalent ion inhibits the reaction [Nickel results in increased phosphorylation of SRC protein]19403854
D007464Clioquinol[[Clioquinol binds to Copper] which results in increased activity of SRC protein] which results in increased phosphorylation of and results in increased activity of EGFR protein18346929
D007464Clioquinol[Clioquinol binds to Copper] which results in increased phosphorylation of and results in increased activity of SRC protein18346929
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to NCF1 protein]]19608869
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to TNFRSF1A protein]]19608869
C007095cobaltiprotoporphyrinzinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to NCF1 protein]]]19608869
C007095cobaltiprotoporphyrinzinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to TNFRSF1A protein]]]19608869
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased phosphorylation of SRC protein]19608869
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [Dietary Fats results in increased expression of SRC protein modified form]22193921
C007095cobaltiprotoporphyrinstannous mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Dietary Fats results in increased expression of SRC protein modified form]]22193921
C018021cobaltous chlorideAG 1879 inhibits the reaction [[cobaltous chloride results in increased activity of SRC protein] which results in increased expression of HIF1A protein]15735682
C018021cobaltous chlorideAG 1879 inhibits the reaction [[cobaltous chloride results in increased activity of SRC protein] which results in increased phosphorylation of STAT3 protein]15735682
C018021cobaltous chlorideAG 1879 inhibits the reaction [cobaltous chloride results in increased phosphorylation of and results in increased activity of SRC protein]15735682
C018021cobaltous chloride[cobaltous chloride results in increased activity of SRC protein] promotes the reaction [[HIF1A protein binds to STAT3 protein modified form] which binds to VEGFA promoter]15735682
C018021cobaltous chloride[cobaltous chloride results in increased activity of SRC protein] promotes the reaction [[[HIF1A protein binds to STAT3 protein modified form] which binds to VEGFA promoter] binds to [APEX1 protein binds to CREBBP promoter]]15735682
C018021cobaltous chloride[cobaltous chloride results in increased activity of SRC protein] which results in increased expression of HIF1A protein15735682
C018021cobaltous chloride[cobaltous chloride results in increased activity of SRC protein] which results in increased phosphorylation of STAT3 protein15735682
C018021cobaltous chloridecobaltous chloride results in increased phosphorylation of and results in increased activity of SRC protein15735682
D003042CocaineCocaine results in decreased activity of SRC protein27506785
D003042CocaineCocaine results in increased phosphorylation of SRC protein20354174
D003042CocaineCocaine affects the expression of SRC mRNA20187946
D003300Copper[[Clioquinol binds to Copper] which results in increased activity of SRC protein] which results in increased phosphorylation of and results in increased activity of EGFR protein18346929
D003300Copper[Clioquinol binds to Copper] which results in increased phosphorylation of and results in increased activity of SRC protein18346929
D003300Copper[Copper binds to N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide] which results in decreased expression of SRC protein16600465
D019327Copper SulfateCopper Sulfate results in increased expression of SRC mRNA19549813
C113861corosolic acidcorosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]26513295
C113861corosolic acidcorosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]26513295
D003474CurcuminCurcumin results in decreased expression of SRC protein16959222
D003474CurcuminCurcumin results in decreased expression of SRC18462866
D003513CycloheximideCycloheximide results in increased localization of SRC protein10401681
D000069439DasatinibDasatinib binds to SRC protein18180381
D000069439DasatinibDasatinib results in decreased activity of SRC protein21106725
D000069439DasatinibDasatinib results in decreased phosphorylation of and results in decreased activity of SRC protein17020995
D000069439DasatinibDasatinib results in decreased phosphorylation of SRC protein19398150|2062907
D000069439Dasatinib[Dasatinib results in decreased phosphorylation of SRC protein] which results in decreased phosphorylation of MET protein21106725
D000069439DasatinibDasatinib results in decreased activity of SRC protein21633166
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of SRC protein23038006
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of SRC mRNA23640034
C017180decamethrindecamethrin results in decreased expression of SRC protein22634059
C014347decitabine[[decitabine affects the methylation of GJB1 promoter] which affects the expression of GJB1 mRNA] which affects the activity of SRC protein18264126
C107676deguelindeguelin metabolite results in increased activity of SRC protein19139008
C107676deguelindeguelin results in increased activity of SRC protein19139008
D003687Dehydroepiandrosterone"4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Dehydroepiandrosterone results in increased phosphorylation of SRC protein]"25969534
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased phosphorylation of SRC protein25969534
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased phosphorylation of SRC protein16407456
D003687DehydroepiandrosteroneDihydrotestosterone inhibits the reaction [Dehydroepiandrosterone results in increased phosphorylation of SRC protein]16407456
D003687DehydroepiandrosteronePertussis Toxin inhibits the reaction [Dehydroepiandrosterone results in increased phosphorylation of SRC protein]16407456
C509625dehydroepiandrosterone-bovine serum albumindehydroepiandrosterone-bovine serum albumin results in increased phosphorylation of SRC protein16407456
C509625dehydroepiandrosterone-bovine serum albuminDexamethasone inhibits the reaction [dehydroepiandrosterone-bovine serum albumin results in increased phosphorylation of SRC protein]16407456
C509625dehydroepiandrosterone-bovine serum albuminPertussis Toxin inhibits the reaction [dehydroepiandrosterone-bovine serum albumin results in increased phosphorylation of SRC protein]16407456
D019314Dehydroepiandrosterone SulfateDehydroepiandrosterone Sulfate results in increased phosphorylation of SRC protein16407456
D003907DexamethasoneDexamethasone inhibits the reaction [dehydroepiandrosterone-bovine serum albumin results in increased phosphorylation of SRC protein]16407456
D003907DexamethasoneDexamethasone results in increased phosphorylation of SRC protein15187100
D003993Dibutyl PhthalateDibutyl Phthalate results in increased phosphorylation of SRC protein22552774
D003993Dibutyl Phthalatefulvestrant inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of SRC protein]22552774
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of SRC mRNA27392435
D002945CisplatinSRC protein results in decreased susceptibility to Cisplatin21291860
D002945Cisplatin"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Cisplatin promotes the reaction [SRC protein binds to PRKCD protein]]"21633170
D002945CisplatinAG 1879 inhibits the reaction [Cisplatin promotes the reaction [SRC protein binds to PRKCD protein]]21633170
D002945CisplatinCisplatin promotes the reaction [SRC protein binds to PRKCD protein]21633170
D002945Cisplatin[Cisplatin promotes the reaction [SRC protein binds to PRKCD protein]] which results in increased activity of PRKCD protein21633170
D004008DiclofenacDiclofenac affects the expression of SRC mRNA24752500
D004026DieldrinDieldrin results in increased expression of SRC mRNA28385952
D004026DieldrinDieldrin affects the expression of SRC mRNA22546817
D004041Dietary Fatscobaltiprotoporphyrin inhibits the reaction [Dietary Fats results in increased expression of SRC protein modified form]22193921
D004041Dietary FatsDietary Fats results in increased expression of SRC protein modified form22193921
D004041Dietary Fatsstannous mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Dietary Fats results in increased expression of SRC protein modified form]]22193921
D004051Diethylhexyl Phthalate[INS1 protein co-treated with Diethylhexyl Phthalate] results in decreased expression of SRC protein28526321
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SRC mRNA18164116
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of SRC mRNA17010207
C058064dinitrophenyl-human serum albumin conjugatedinitrophenyl-human serum albumin conjugate results in increased activity of SRC protein26621445
C058064dinitrophenyl-human serum albumin conjugateresveratrol inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased activity of SRC protein]26621445
C019357dioscindioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of SRC protein]25111127
D016291Dizocilpine MaleateDizocilpine Maleate promotes the reaction [GRIN1 protein binds to SRC protein]11249956
D016291Dizocilpine MaleateDizocilpine Maleate results in increased activity of SRC protein11249956
D016291Dizocilpine MaleateDizocilpine Maleate results in increased expression of SRC mRNA11249956
D016291Dizocilpine MaleateDizocilpine Maleate results in increased expression of SRC protein11249956
D016291Dizocilpine MaleateDizocilpine Maleate results in increased phosphorylation of and results in increased activity of SRC protein11249956
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [EGF protein results in increased phosphorylation of SRC protein]"25856345
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased phosphorylation of SRC protein"25856345
D004365Drugs, Chinese Herbal"[Drugs, Chinese Herbal co-treated with niuhuang] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of SRC protein]"23256447
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of SRC mRNA"23262642
D004642EmodinEmodin results in decreased phosphorylation of SRC protein23848338
D060754Equol[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased activity of and results in increased phosphorylation of NOS3 protein]21300668
D060754Equol[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK1 protein]21300668
D060754Equol[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Equol results in increased phosphorylation of MAPK3 protein]21300668
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride results in decreased phosphorylation of SRC protein23894143
C025483estradiol-17 beta-glucuronideestradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein25813982
C025483estradiol-17 beta-glucuronideProtein Kinase Inhibitors inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein]25813982
C025483estradiol-17 beta-glucuronidetyrphostin AG 1478 inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein]25813982
C007633estragoleestragole results in increased phosphorylation of SRC protein29054680
D000431EthanolEthanol results in increased expression of SRC mRNA20655511|2327357
C422415farglitazarfarglitazar binds to and results in increased activity of SRC protein22070604
D005372Filipin"Filipin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of SRC protein]"19632255
D005419FlavonoidsFlavonoids results in increased expression of SRC mRNA18035473
D005459FluoridesFluorides results in decreased expression of SRC mRNA22610969
D005472FluorouracilFluorouracil results in increased phosphorylation of SRC protein18794807
D005472FluorouracilSRC protein affects the susceptibility to Fluorouracil18794807
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SRC mRNA20938992
D009240N-Formylmethionine Leucyl-PhenylalanineAG 1879 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of SRC protein]25980585
D009240N-Formylmethionine Leucyl-Phenylalaninehonokiol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of SRC protein]25980585
D009240N-Formylmethionine Leucyl-PhenylalanineN-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of SRC protein25980585
C069837fullerene C60fullerene C60 results in decreased expression of SRC mRNA19167457
C070081fulvestrantfulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of SRC protein]22552774
C070081fulvestrantfulvestrant inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of SRC protein]22552774
D005707Gallic AcidGallic Acid inhibits the reaction [EGF protein results in increased activity of SRC protein]27087131
D005707Gallic AcidSRC protein modified form affects the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]]27087131
D005707Gallic AcidSRC protein modified form inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]27087131
D005707Gallic AcidSRC protein modified form inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]]27087131
D005707Gallic AcidSRC protein modified form inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]]27087131
D005707Gallic AcidSRC protein modified form inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]]27087131
D005707Gallic AcidSRC protein modified form inhibits the reaction [Gallic Acid inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]]27087131
C054597garcinolgarcinol results in decreased phosphorylation of and results in decreased activity of SRC protein16052481
C419708gefitinibgefitinib results in decreased activity of SRC protein22573732
C001277geldanamycingeldanamycin inhibits the reaction [HSP90AA1 protein binds to SRC protein binds to CDC37 protein]17223712
C001277geldanamycingeldanamycin inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of SRC protein]17223712
C001277geldanamycingeldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of SRC protein]10401681
C056507gemcitabine[AG 1879 co-treated with SRC] results in increased susceptibility to gemcitabine15073106
C056507gemcitabineSRC protein affects the susceptibility to gemcitabine15073106
C056507gemcitabineSRC protein modified form results in decreased susceptibility to gemcitabine15073106
C056507gemcitabineSRC protein results in decreased susceptibility to gemcitabine15194078
D019833Genisteinbisphenol A inhibits the reaction [Genistein results in decreased expression of SRC protein]24884420
D019833GenisteinGenistein inhibits the reaction [bisphenol A results in increased expression of SRC protein]24884420
D019833GenisteinGenistein results in decreased activity of SRC protein15592923
D019833GenisteinGenistein results in decreased expression of SRC protein24884420
D005947Glucose[resveratrol co-treated with Glucose] results in decreased expression of SRC mRNA24659233
D005947Glucose[resveratrol co-treated with Glucose] results in decreased expression of SRC protein24659233
D005947Glucose[resveratrol co-treated with Glucose] results in decreased expression of SRC protein modified form24659233
D005947GlucoseSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]11990355
D006003GlycogenSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased abundance of Glycogen]11882352
C081021Go 6976Go 6976 inhibits the reaction [IL1B protein results in increased phosphorylation of SRC protein]19281832
C544831GSK 1363089GSK 1363089 results in decreased phosphorylation of SRC protein22241084
D006581Hexachlorobenzene[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein]21205633
D006581Hexachlorobenzene[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of STAT5B protein]21205633
D006581Hexachlorobenzene[AG 1879 results in decreased activity of SRC protein] which results in decreased susceptibility to Hexachlorobenzene21205633
D006581HexachlorobenzeneHexachlorobenzene affects the localization of SRC protein28215542
D006581HexachlorobenzeneHexachlorobenzene affects the phosphorylation of and affects the activity of SRC protein19879930
D006581HexachlorobenzeneHexachlorobenzene affects the reaction [CDKN1B protein binds to SRC protein]28215542
D006581HexachlorobenzeneHexachlorobenzene results in increased phosphorylation of SRC protein21205633|2346230
D006581HexachlorobenzeneAG 1879 inhibits the reaction [SRC protein promotes the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein]]18295415
D006581HexachlorobenzeneHexachlorobenzene promotes the reaction [EGFR protein binds to SRC protein]18295415|2224512
D006581HexachlorobenzeneHexachlorobenzene promotes the reaction [ESR1 protein binds to SRC protein]22245120
D006581HexachlorobenzeneHexachlorobenzene promotes the reaction [Methylnitrosourea promotes the reaction [EGFR protein binds to SRC protein]]22245120
D006581HexachlorobenzeneHexachlorobenzene promotes the reaction [Methylnitrosourea results in increased phosphorylation of SRC protein]22245120
D006581HexachlorobenzeneHexachlorobenzene results in increased expression of and results in increased phosphorylation of and results in increased activity of SRC protein18295415
D006581HexachlorobenzeneHexachlorobenzene results in increased phosphorylation of and results in increased expression of SRC protein22245120
D006581HexachlorobenzeneMethylnitrosourea inhibits the reaction [Hexachlorobenzene promotes the reaction [ESR1 protein binds to SRC protein]]22245120
D006581HexachlorobenzeneMethylnitrosourea promotes the reaction [Hexachlorobenzene promotes the reaction [EGFR protein binds to SRC protein]]22245120
D006581HexachlorobenzeneMethylnitrosourea promotes the reaction [Hexachlorobenzene results in increased phosphorylation of SRC protein]22245120
D006581HexachlorobenzeneSRC protein promotes the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein]18295415
C005499honokiolhonokiol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of SRC protein]25980585
C062018HU 211HU 211 results in increased phosphorylation of SRC protein16046413
C062018HU 211Pertussis Toxin inhibits the reaction [HU 211 results in increased phosphorylation of SRC protein]16046413
C062018HU 211RALA affects the reaction [HU 211 results in increased phosphorylation of SRC protein]16046413
C062018HU 211rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of SRC protein]16046413
D006820Hyaluronic AcidHyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of SRC protein]23178681
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [beta-methylcholine results in increased phosphorylation of SRC protein]21179406
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of SRC protein12902192
D006861Hydrogen PeroxideHSPB1 protein inhibits the reaction [[Hydrogen Peroxide affects the activity of SRC protein] which results in increased activity of MAPK1 protein]14975446
D006861Hydrogen PeroxideHSPB1 protein inhibits the reaction [[Hydrogen Peroxide affects the activity of SRC protein] which results in increased activity of MAPK3 protein]14975446
D006861Hydrogen Peroxide[Hydrogen Peroxide affects the activity of SRC protein] which results in increased activity of MAPK1 protein14975446
D006861Hydrogen Peroxide[Hydrogen Peroxide affects the activity of SRC protein] which results in increased activity of MAPK3 protein14975446
D006861Hydrogen PeroxideHyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of SRC protein]23178681
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [PTK2B protein binds to SRC protein]15705590
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased phosphorylation of SRC protein23178681
D006861Hydrogen PeroxidePLD2 protein affects the reaction [Hydrogen Peroxide promotes the reaction [PTK2B protein binds to SRC protein]]15705590
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [BDNF protein results in increased phosphorylation of SRC protein]21179406
C014290hydroxyflutamidehydroxyflutamide inhibits the reaction [Testosterone results in increased phosphorylation of SRC protein]26437446
C014290hydroxyflutamidehydroxyflutamide results in decreased phosphorylation of SRC protein26437446
D007200Indican[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Indican results in increased phosphorylation of SRC protein]23639249
D007200Indican[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Indican results in increased phosphorylation of STAT3 protein]23639249
D007200IndicanIndican results in increased phosphorylation of SRC protein23639249
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SRC mRNA25613284
D007501IronIron promotes the reaction [Arsenic results in increased phosphorylation of and results in increased activity of SRC protein]23100159
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of SRC mRNA27392435
C544151jinfukangjinfukang results in increased expression of SRC mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of SRC mRNA26752646
C072105KN 93KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of SRC protein]19233221
C490728lapatinib[lapatinib results in decreased susceptibility to lapatinib] which results in increased phosphorylation of SRC protein26643609
C490728lapatinibNiclosamide inhibits the reaction [[lapatinib results in decreased susceptibility to lapatinib] which results in increased phosphorylation of SRC protein]26643609
D007854LeadHSPA5 protein affects the reaction [Lead results in increased phosphorylation of SRC protein]24431214
D007854LeadLead results in increased phosphorylation of and results in increased expression of SRC protein24431214
C008261lead acetate"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [lead acetate results in increased phosphorylation of SRC protein]"19133285
C008261lead acetateEGFR mutant form inhibits the reaction [lead acetate results in increased phosphorylation of SRC protein]19133285
C008261lead acetatelead acetate results in increased phosphorylation of SRC protein19133285
C008261lead acetatelead acetate results in increased phosphorylation of SRC protein26926986
C440499lipopolysaccharide, Escherichia coli O111 B4"[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of SRC protein"20060843
C440499lipopolysaccharide, Escherichia coli O111 B4"Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of SRC protein]"20060843
D008070LipopolysaccharidesAG 1879 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of SRC protein]23735482
D008070Lipopolysaccharides"[Drugs, Chinese Herbal co-treated with niuhuang] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of SRC protein]"23256447
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of SRC protein23362215
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of SRC mRNA12057914
D008070LipopolysaccharidesLipopolysaccharides results in increased activity of and results in increased phosphorylation of SRC protein23735482
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of SRC mRNA25890327
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of SRC protein23256447
D008070LipopolysaccharidesQuercetin inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased phosphorylation of SRC protein]23735482
D008070Lipopolysaccharideswogonin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of SRC protein]23362215
D008094Lithium[Lithium co-treated with Pilocarpine] results in increased activity of SRC protein16600505
D017998Leukotriene D4Leukotriene D4 promotes the reaction [SRC protein binds to PDGFRB protein]12223454
D017998Leukotriene D4Leukotriene D4 results in increased phosphorylation of and results in increased activity of SRC protein12223454
D017998Leukotriene D4pobilukast inhibits the reaction [Leukotriene D4 results in increased activity of SRC protein]12223454
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in increased expression of SRC mRNA21641980
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of SRC mRNA26378955
D008345Manganese[Manganese binds to N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide] which results in decreased expression of SRC protein16600465
C025340manganese chloride[AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]15213856
C025340manganese chloride[CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]15213856
D008353MannitolMannitol inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein]16510265
C412811maslinic acidmaslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]26513295
C412811maslinic acidmaslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]26513295
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SRC mRNA20938992
D008727MethotrexateMethotrexate results in decreased expression of SRC mRNA17400583
D008727MethotrexateMethotrexate results in increased expression of SRC mRNA21678067
D008727MethotrexateMethotrexate affects the expression of SRC mRNA18502557
C013598methoxyacetic acidmethoxyacetic acid affects the expression of SRC protein11794376
C108732methyl-beta-cyclodextrinmethyl-beta-cyclodextrin inhibits the reaction [Estradiol promotes the reaction [SRC protein modified form binds to CAV1 protein]]18296501
C108732methyl-beta-cyclodextrinmethyl-beta-cyclodextrin inhibits the reaction [resveratrol promotes the reaction [SRC protein modified form binds to CAV1 protein]]18296501
C108732methyl-beta-cyclodextrin"methyl-beta-cyclodextrin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of SRC protein]"19632255
C005219methyl cellosolvemethyl cellosolve metabolite affects the expression of SRC protein11794376
D008748MethylcholanthreneMethylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [SRC protein binds to AHR protein]]8937476
D008748MethylcholanthreneMethylcholanthrene affects the expression of SRC mRNA23273579
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of SRC mRNA26011545
D008770MethylnitrosoureaHexachlorobenzene promotes the reaction [Methylnitrosourea promotes the reaction [EGFR protein binds to SRC protein]]22245120
D008770MethylnitrosoureaHexachlorobenzene promotes the reaction [Methylnitrosourea results in increased phosphorylation of SRC protein]22245120
D008770MethylnitrosoureaMethylnitrosourea inhibits the reaction [Hexachlorobenzene promotes the reaction [ESR1 protein binds to SRC protein]]22245120
D008770MethylnitrosoureaMethylnitrosourea promotes the reaction [EGFR protein binds to SRC protein]22245120
D008770MethylnitrosoureaMethylnitrosourea promotes the reaction [Hexachlorobenzene promotes the reaction [EGFR protein binds to SRC protein]]22245120
D008770MethylnitrosoureaMethylnitrosourea promotes the reaction [Hexachlorobenzene results in increased phosphorylation of SRC protein]22245120
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of SRC protein22245120
D008770MethylnitrosoureaMethylnitrosourea results in increased phosphorylation of and results in increased expression of SRC protein22245120
D015741MetriboloneMetribolone results in increased phosphorylation of and results in increased activity of SRC protein17272394
C066851mithramycin Amithramycin A results in decreased expression of SRC protein19799886
C016599mono-(2-ethylhexyl)phthalate[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of SRC protein28526321
C020300monomethylarsonic acid[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of SRC mRNA23192986
C406082monomethylarsonous acid[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [monomethylarsonous acid results in increased expression of PTGS2 protein]17093206
C406082monomethylarsonous acidmonomethylarsonous acid results in increased phosphorylation of SRC protein18588940
C406082monomethylarsonous acidPotassium Iodide inhibits the reaction [monomethylarsonous acid results in increased phosphorylation of SRC protein]18588940
C406082monomethylarsonous acidSRC protein affects the reaction [monomethylarsonous acid results in increased expression of PTGS2 protein]17093206
C524250N'-(11H-indolo(3,2-c)quinolin-6-yl)-N,N-dimethylethane-1,2-diamine"N'-(11H-indolo(3,2-c)quinolin-6-yl)-N,N-dimethylethane-1,2-diamine results in decreased phosphorylation of and results in decreased activity of SRC protein"18638462
C516322N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide[Copper binds to N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide] which results in decreased expression of SRC protein16600465
C516322N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide[Manganese binds to N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide] which results in decreased expression of SRC protein16600465
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased activity of SRC protein"29112861
C073873naphtho(1,2-b)furan-4,5-dione"naphtho(1,2-b)furan-4,5-dione results in decreased phosphorylation of SRC protein"20197088
D009532Nickelchromium hexavalent ion inhibits the reaction [Nickel results in increased phosphorylation of SRC protein]19403854
D009532NickelNickel results in increased phosphorylation of SRC protein19403854
D009532NickelU 0126 inhibits the reaction [Nickel results in increased phosphorylation of SRC protein]19403854
D009532NickelNickel affects the phosphorylation of SRC protein11333182
C017557nickel subsulfidenickel subsulfide results in decreased expression of SRC mRNA24952340
D009534NiclosamideNiclosamide inhibits the reaction [[lapatinib results in decreased susceptibility to lapatinib] which results in increased phosphorylation of SRC protein]26643609
D009538NicotineARRB1 protein affects the reaction [Nicotine results in increased phosphorylation of and results in increased activity of SRC protein]16862215
D009538NicotineNicotine results in increased phosphorylation of and results in increased activity of SRC protein16862215
D009538NicotineNicotine results in increased phosphorylation of SRC protein14569062
D009538NicotineSRC protein affects the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]]16862215
D009538Nicotinetyrphostin AG 1478 inhibits the reaction [Nicotine results in increased phosphorylation of SRC protein]14569062
D009543NifedipineNifedipine inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased activity of SRC protein]19556728
D009543NifedipineNifedipine inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of SRC protein modified form]19556728
D009569Nitric Oxide[resveratrol promotes the reaction [ESR1 protein binds to CAV1 protein binds to SRC protein]] which results in increased abundance of Nitric Oxide18296501
C570000niuhuang"[Drugs, Chinese Herbal co-treated with niuhuang] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of SRC protein]"23256447
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased phosphorylation of SRC protein]"12972402
C025589ochratoxin Aochratoxin A results in increased phosphorylation of SRC protein25002221
C474055octylphenoloctylphenol results in increased expression of SRC mRNA17010207
C030110oxaliplatinoxaliplatin results in increased phosphorylation of and results in increased activity of SRC protein18790786
C029341oxophenylarsineoxophenylarsine inhibits the reaction [PRSS1 protein results in decreased phosphorylation of and results in increased activity of SRC protein]11035913
C029341oxophenylarsineoxophenylarsine affects the localization of SRC protein9546377
D010100OxygenAG 1879 inhibits the reaction [Oxygen deficiency results in increased phosphorylation of and results in increased activity of SRC protein]17671207
D010100OxygenOxygen deficiency results in increased phosphorylation of and results in increased activity of SRC protein17671207
D010100Oxygen"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Oxygen deficiency results in increased phosphorylation of SRC protein]"15913578
D010100OxygenOxygen deficiency results in increased phosphorylation of SRC protein15913578
D010100OxygenRotenone inhibits the reaction [Oxygen deficiency results in increased phosphorylation of SRC protein]15913578
D010100OxygenOxygen deficiency results in increased phosphorylation of SRC protein15913578
D010126OzoneOzone results in increased phosphorylation of SRC protein25303742
C115711PD 173074[arsenic trioxide co-treated with PD 173074] results in decreased expression of SRC protein27794399
C115711PD 173074[arsenic trioxide results in increased susceptibility to PD 173074] which results in decreased expression of SRC protein27794399
C115711PD 173074benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[arsenic trioxide co-treated with PD 173074] results in decreased expression of SRC protein]27794399
C115711PD 173074PD 173074 promotes the reaction [arsenic trioxide results in decreased expression of SRC protein]27794399
C115711PD 173074PD 173074 promotes the reaction [arsenic trioxide results in decreased expression of SRC protein modified form]27794399
C115711PD 173074PD 173074 results in decreased expression of SRC protein27794399
C115711PD 173074PD 173074 results in decreased expression of SRC protein modified form27794399
C115711PD 173074[PD 173074 results in increased susceptibility to arsenic trioxide] which results in decreased expression of SRC protein27794399
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of SRC protein26879310
C069276peroxovanadateperoxovanadate results in increased phosphorylation of SRC protein23298284
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [HU 211 results in increased phosphorylation of SRC protein]16046413
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [dehydroepiandrosterone-bovine serum albumin results in increased phosphorylation of SRC protein]16407456
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [Dehydroepiandrosterone results in increased phosphorylation of SRC protein]16407456
D010622PhencyclidinePhencyclidine results in increased expression of SRC mRNA11249956
D010634PhenobarbitalPhenobarbital results in decreased expression of SRC mRNA23273579
D010862Pilocarpine[Lithium co-treated with Pilocarpine] results in increased activity of SRC protein16600505
C049032pinosylvinpinosylvin results in decreased expression of SRC protein modified form23333577
C037850PK 11195PK 11195 inhibits the reaction [SRC protein binds to NR1I3 protein]24224465
D010936Plant ExtractsPlant Extracts results in decreased phosphorylation of SRC protein27322511
D010936Plant ExtractsPlant Extracts results in increased phosphorylation of SRC protein25051199
D010936Plant ExtractsPlant Extracts results in increased expression of SRC mRNA23262642
D028321Plant PreparationsPlant Preparations results in increased expression of SRC mRNA24973489
C052393pobilukastpobilukast inhibits the reaction [Leukotriene D4 results in increased activity of SRC protein]12223454
D020959PolyethylenePolyethylene results in increased expression of SRC mRNA15585240
C545373ponatinibponatinib analog results in decreased activity of SRC protein21561767
C545373ponatinibponatinib results in decreased activity of SRC protein19878872
C545373ponatinibponatinib inhibits the reaction [FGFR1 protein mutant form results in increased phosphorylation of SRC protein]22781593
D011189Potassium ChlorideCAMK2D protein affects the reaction [Potassium Chloride results in increased phosphorylation of SRC protein]18004999
D011189Potassium ChloridePotassium Chloride results in increased phosphorylation of SRC protein18004999
D011189Potassium ChlorideSRC protein affects the reaction [Potassium Chloride results in increased phosphorylation of and results in increased activity of CREB1 protein]18004999
D011189Potassium ChlorideSRC protein affects the reaction [Potassium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]18004999
D011189Potassium ChlorideSRC protein affects the reaction [Potassium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]18004999
D017419Potassium, Dietary"Potassium, Dietary results in decreased expression of SRC protein"10787405
D011193Potassium IodidePotassium Iodide inhibits the reaction [monomethylarsonous acid results in increased phosphorylation of SRC protein]18588940
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein]25813982
C527556Pt(O,O'-acac)(gamma-acac)(DMS)"[Pt(O,O'-acac)(gamma-acac)(DMS) results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of SRC protein"21420390
C527556Pt(O,O'-acac)(gamma-acac)(DMS)"Pt(O,O'-acac)(gamma-acac)(DMS) results in increased phosphorylation of SRC protein"21420390
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased expression of and results in increased phosphorylation of SRC protein14559718
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog results in decreased expression of and results in decreased phosphorylation of SRC protein"21152443
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog results in decreased expression of SRC protein"21152443
D011794QuercetinQuercetin results in decreased phosphorylation of SRC protein24275163|2561156
D011794Quercetin"Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of SRC protein]"20060843
D011794QuercetinQuercetin inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased phosphorylation of SRC protein]23735482
D011794QuercetinQuercetin results in decreased phosphorylation of SRC protein24275163
D011794QuercetinQuercetin results in decreased activity of SRC protein19814731
C110310quercetin 4'-O-glucopyranosidequercetin 4'-O-glucopyranoside analog inhibits the reaction [VEGFA protein results in increased phosphorylation of SRC protein]22348123
C012526quercitrinquercitrin affects the expression of SRC mRNA25193878
D017382Reactive Oxygen Species"[Pt(O,O'-acac)(gamma-acac)(DMS) results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of SRC protein"21420390
D017382Reactive Oxygen Species[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein23376140
D017382Reactive Oxygen Species[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein23376140
D017382Reactive Oxygen Species[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein23376140
D017382Reactive Oxygen Species[[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein] promotes the reaction [STAT3 protein binds to STAT3 protein]23376140
C059514resveratrolmethyl-beta-cyclodextrin inhibits the reaction [resveratrol promotes the reaction [SRC protein modified form binds to CAV1 protein]]18296501
C059514resveratrolresveratrol promotes the reaction [SRC protein binds to CAV1 protein]18296501
C059514resveratrolresveratrol promotes the reaction [SRC protein modified form binds to CAV1 protein]18296501
C059514resveratrolresveratrol promotes the reaction [SRC protein modified form binds to SRC protein]18296501
C059514resveratrolAG 1879 inhibits the reaction [resveratrol results in increased phosphorylation of SRC protein]17513867
C059514resveratrolESR1 protein promotes the reaction [resveratrol results in increased phosphorylation of SRC protein]18296501
C059514resveratrolresveratrol affects the phosphorylation of SRC protein22634503
C059514resveratrol[resveratrol affects the phosphorylation of SRC protein] affects the reaction [sodium arsenite results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]]22634503
C059514resveratrolresveratrol promotes the reaction [ESR1 protein binds to CAV1 protein binds to SRC protein]18296501
C059514resveratrol[resveratrol promotes the reaction [ESR1 protein binds to CAV1 protein binds to SRC protein]] which results in increased abundance of Nitric Oxide18296501
C059514resveratrolresveratrol results in decreased phosphorylation of and results in decreased activity of SRC protein16546976
C059514resveratrolresveratrol results in decreased phosphorylation of SRC protein26138072|2691133
C059514resveratrolresveratrol results in increased activity of SRC protein15615701
C059514resveratrolresveratrol results in increased phosphorylation of SRC protein17513867|1829650
C059514resveratrolresveratrol results in decreased activity of SRC protein18567737
C059514resveratrolresveratrol results in decreased expression of SRC protein modified form18567737
C059514resveratrol[resveratrol co-treated with Glucose] results in decreased expression of SRC mRNA24659233
C059514resveratrol[resveratrol co-treated with Glucose] results in decreased expression of SRC protein24659233
C059514resveratrol[resveratrol co-treated with Glucose] results in decreased expression of SRC protein modified form24659233
C059514resveratrolresveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]26100520
C059514resveratrolresveratrol promotes the reaction [ursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]]26100520
C059514resveratrolresveratrol results in decreased phosphorylation of SRC protein26138072
C059514resveratrolursolic acid promotes the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]]26100520
C059514resveratrolresveratrol inhibits the reaction [1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased phosphorylation of SRC protein]24079413
C059514resveratrolresveratrol inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased activity of SRC protein]26621445
C059514resveratrolresveratrol inhibits the reaction [IL1B protein results in increased phosphorylation of SRC protein]22936809
C059514resveratrolresveratrol inhibits the reaction [VEGFA protein results in increased activity of SRC protein]14573751
C059514resveratrolresveratrol results in decreased activity of SRC protein11408617
C059514resveratrolSRC protein mutant form inhibits the reaction [resveratrol inhibits the reaction [VEGFA protein results in increased phosphorylation of CDH5 protein]]14573751
C013672riddelliineriddelliine results in increased expression of SRC mRNA18047727
D012293Rifampinallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]25069801
D012293Rifampinallyl isothiocyanate inhibits the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]25069801
D012293RifampinNR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]25069801
D012293Rifampin[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA25069801
C089032rimonabantrimonabant inhibits the reaction [HU 211 results in increased phosphorylation of SRC protein]16046413
D019438RitonavirRitonavir results in decreased phosphorylation of SRC protein21270666
C089730rosiglitazonerosiglitazone binds to and results in increased activity of SRC protein22070604
D012402RotenoneRotenone inhibits the reaction [Oxygen deficiency results in increased phosphorylation of SRC protein]15913578
C480767SB219994SB219994 binds to and results in increased activity of SRC protein22070604
D020123SirolimusSirolimus results in increased phosphorylation of and results in increased activity of SRC protein19151764
D020123Sirolimus[Sirolimus results in increased phosphorylation of and results in increased activity of SRC protein] which results in increased phosphorylation of EGFR protein19151764
D020123Sirolimus[Sirolimus results in increased phosphorylation of and results in increased activity of SRC protein] which results in increased phosphorylation of MAPK1 protein19151764
D020123Sirolimus[Sirolimus results in increased phosphorylation of and results in increased activity of SRC protein] which results in increased phosphorylation of MAPK3 protein19151764
C017947sodium arsenite[resveratrol affects the phosphorylation of SRC protein] affects the reaction [sodium arsenite results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]]22634503
C017947sodium arsenite[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of SRC mRNA23192986
C017947sodium arsenitesodium arsenite results in increased activity of SRC protein11723127|2263450
C017947sodium arsenitesodium arsenite promotes the reaction [SRC protein binds to EGFR protein]11723127
C471405sorafenibsorafenib inhibits the reaction [SRC protein results in increased phosphorylation of STAT3 protein]20881478
C471405sorafenibsorafenib results in decreased activity of SRC protein20881478
C518404stannous mesoporphyrinstannous mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Dietary Fats results in increased expression of SRC protein modified form]]22193921
C416927SU 6656SU 6656 results in decreased activity of SRC protein23527294
C416927SU 6656[SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased expression of MT2 protein]23376140
C416927SU 6656[SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of EGFR protein]23376140
C416927SU 6656[SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]23376140
C416927SU 6656[SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]23376140
C416927SU 6656[[tyrphostin AG 1478 results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]23376140
C416927SU 6656SU 6656 results in decreased activity of SRC protein23376140
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in increased expression of SRC mRNA21641980
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of SRC mRNA26378955
D013467SulindacSulindac results in increased phosphorylation of and results in decreased activity of SRC protein18644992
D013467Sulindac[[Azoxymethane co-treated with Sulindac] results in increased expression of CSK protein] which results in increased phosphorylation of and results in decreased activity of SRC protein18644992
D014284TriiodothyronineSRC inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]22227104
D014284TriiodothyronineSRC inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]22227104
D014284Triiodothyronine2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
D014284TriiodothyronineAG 1879 inhibits the reaction [Triiodothyronine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
D014284Triiodothyroninebisphenol A inhibits the reaction [Triiodothyronine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
D014284Triiodothyroninetetraiodothyroacetic acid inhibits the reaction [Triiodothyronine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
D014284TriiodothyronineTriiodothyronine promotes the reaction [SRC protein binds to ITGB3 protein]22227104
D013629TamoxifenSRC protein promotes the reaction [Tamoxifen results in increased phosphorylation of and results in increased activity of MAPK1 protein]20211987
D013629TamoxifenSRC protein promotes the reaction [Tamoxifen results in increased phosphorylation of and results in increased activity of MAPK3 protein]20211987
D013739Testosteronehydroxyflutamide inhibits the reaction [Testosterone results in increased phosphorylation of SRC protein]26437446
D013739TestosteroneTestosterone promotes the reaction [SRC protein binds to AR protein]17272394
D013739TestosteroneTestosterone results in increased phosphorylation of and results in increased activity of SRC protein17272394
D013739TestosteroneTestosterone results in increased phosphorylation of SRC protein21177760|2643744
D013739TestosteroneTestosterone results in increased activity of SRC protein20403869
C045037testosterone-3-carboxymethyloxime-bovine serum albumin conjugatetestosterone-3-carboxymethyloxime-bovine serum albumin conjugate affects the expression of SRC mRNA20189893
D013749Tetrachlorodibenzodioxinalpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of SRC protein]8937476
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased activity of [SRC protein binds to AHR protein]8937476
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of SRC protein8937476
D013749Tetrachlorodibenzodioxin3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]21145940
D013749TetrachlorodibenzodioxinAG 1879 inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]21145940
D013749Tetrachlorodibenzodioxingeldanamycin inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of SRC protein]17223712
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [[Dihydrotestosterone co-treated with Tetrachlorodibenzodioxin] results in increased activity of AR protein]19815066
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the localization of SRC protein17223712
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [CDC37 protein binds to SRC protein]17223712
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of SRC mRNA20106945|2163298
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased phosphorylation of SRC protein21145940
D013749Tetrachlorodibenzodioxin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]19782052
D013749Tetrachlorodibenzodioxin3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]19782052
D013749TetrachlorodibenzodioxinAG 1879 inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]19782052
D013749Tetrachlorodibenzodioxin[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]23639249
D013749Tetrachlorodibenzodioxin[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of STAT3 protein]23639249
D013749Tetrachlorodibenzodioxin[AG 1879 results in decreased activity of SRC protein] which results in decreased susceptibility to Tetrachlorodibenzodioxin23639249
D013749TetrachlorodibenzodioxinCalcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of SRC protein]19782052
D013749TetrachlorodibenzodioxinMethylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [SRC protein binds to AHR protein]]8937476
D013749TetrachlorodibenzodioxinPTGES protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of SRC mRNA]22430074
D013749TetrachlorodibenzodioxinSRC protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TGFB1 mRNA]14708085
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin affects the expression of TFAP2C mRNA]14708085
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin affects the expression of TRP53 mRNA]14708085
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]]14505802
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA]]14505802
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased abundance of Glycogen]11882352
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CEBPA mRNA]14708085
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CEBPB mRNA]14708085
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of NMT1 mRNA]14708085
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of PCK1 mRNA]11882352
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]11990355
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CEBPB protein]14505802
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CEBPD protein]14505802
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPB mRNA]14505802
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPD mRNA]14505802
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PDGFA mRNA]14708085
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PDGFRA mRNA]14708085
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of STAT3 mRNA]14708085
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of TGFA mRNA]14708085
D013749TetrachlorodibenzodioxinSRC protein results in increased susceptibility to Tetrachlorodibenzodioxin11882352
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SRC mRNA26377647
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased activity of SRC protein8937476|9380030
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased activity of [SRC protein binds to AHR protein]8937476
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of SRC mRNA14708085|1690651
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of SRC protein3380784
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased phosphorylation of SRC protein19782052|2363924
D013749TetrachlorodibenzodioxinTGFA gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SRC mRNA]16906519
D013749Tetrachlorodibenzodioxingeldanamycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of SRC protein]10401681
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]11133817
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased activity of SRC protein15592923
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased localization of SRC protein10401681
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein28527916
D013755Tetradecanoylphorbol Acetatecorosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]26513295
D013755Tetradecanoylphorbol Acetatecorosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]26513295
D013755Tetradecanoylphorbol Acetatemaslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]26513295
D013755Tetradecanoylphorbol Acetatemaslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]26513295
D013755Tetradecanoylphorbol Acetateresveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]26100520
D013755Tetradecanoylphorbol Acetateresveratrol promotes the reaction [ursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]]26100520
D013755Tetradecanoylphorbol AcetateSRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]20660715
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of SRC26100520
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein26513295
D013755Tetradecanoylphorbol Acetateursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]26100520
D013755Tetradecanoylphorbol Acetateursolic acid promotes the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]]26100520
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SRC mRNA25613284
C011126tetraiodothyroacetic acidtetraiodothyroacetic acid inhibits the reaction [Thyroxine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
C011126tetraiodothyroacetic acidtetraiodothyroacetic acid inhibits the reaction [Triiodothyronine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
D013974ThyroxineSRC inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]22227104
D013974ThyroxineSRC inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]22227104
D013974Thyroxine2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Thyroxine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
D013974ThyroxineAG 1879 inhibits the reaction [Thyroxine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
D013974Thyroxinebisphenol A inhibits the reaction [Thyroxine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
D013974Thyroxinetetraiodothyroacetic acid inhibits the reaction [Thyroxine promotes the reaction [SRC protein binds to ITGB3 protein]]22227104
D013974ThyroxineThyroxine promotes the reaction [SRC protein binds to ITGB3 protein]22227104
C009495titanium dioxidetitanium dioxide results in increased expression of SRC mRNA29128614
C011559tributyltintributyltin affects the methylation of SRC 5' UTR28011154
C011559tributyltintributyltin affects the methylation of SRC exon28011154
C011559tributyltintributyltin affects the methylation of SRC promoter28011154
C000608764triphenyl(phenylethynyl)phosphoniumtriphenyl(phenylethynyl)phosphonium results in decreased expression of SRC protein26984758
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [EGF protein results in increased phosphorylation of SRC protein]25856345
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [Nicotine results in increased phosphorylation of SRC protein]14569062
C101044tyrphostin AG 1478[[tyrphostin AG 1478 results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]23376140
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein]25813982
C113580U 0126U 0126 inhibits the reaction [Nickel results in increased phosphorylation of SRC protein]19403854
C005466ursolic acidresveratrol promotes the reaction [ursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]]26100520
C005466ursolic acidursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]26100520
C005466ursolic acidursolic acid promotes the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]]26100520
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SRC mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of SRC mRNA26272509|2800136
D014635Valproic AcidValproic Acid results in increased methylation of SRC gene29154799
D014638VanadatesSRC protein affects the susceptibility to Vanadates17551092
D014638VanadatesVanadates promotes the reaction [zinc chloride results in increased phosphorylation of SRC protein]21575692
D014638VanadatesVanadates results in increased phosphorylation of SRC protein21575692
C025643vinclozolinvinclozolin results in decreased expression of SRC mRNA23034163
D014801Vitamin A"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein]"16510265
D014801Vitamin AMannitol inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein]16510265
D014801Vitamin AVitamin A results in increased phosphorylation of SRC protein16510265
C111237vorinostatvorinostat results in increased expression of SRC mRNA26238599
C085514wogoninwogonin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of SRC protein]23362215
C009687wortmanninwortmannin inhibits the reaction [EGF protein results in increased phosphorylation of SRC protein]25856345
C009687wortmanninwortmannin inhibits the reaction [IL1B protein results in increased phosphorylation of SRC protein]22936809
C104536xanthohumolxanthohumol inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]23994090
D015032Zinc"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased phosphorylation of SRC protein]"12972402
D015032ZincZinc deficiency results in increased expression of SRC mRNA18356318
D015032ZincZinc results in decreased activity of SRC protein16410015
D015032ZincZinc results in increased phosphorylation of SRC protein12915106|1297240
D015032Zinc[SRC protein results in increased phosphorylation of EGFR protein] affects the reaction [[Zinc co-treated with EGFR protein] results in increased activity of RAS protein]11983694
D015032ZincZinc deficiency results in increased phosphorylation of SRC protein20101602
D015032ZincZinc promotes the reaction [EGFR protein binds to SRC protein]11983694
D015032ZincZinc results in increased phosphorylation of and results in increased activity of SRC protein11983694
C016837zinc chloride"1,3-dimethylthiourea inhibits the reaction [zinc chloride results in increased phosphorylation of SRC protein]"21575692
C016837zinc chlorideAG 1879 inhibits the reaction [zinc chloride results in increased phosphorylation of SRC protein]12211081
C016837zinc chlorideVanadates promotes the reaction [zinc chloride results in increased phosphorylation of SRC protein]21575692
C016837zinc chloridezinc chloride results in increased phosphorylation of SRC protein12211081|2157569
C017803zinc protoporphyrinzinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to NCF1 protein]]]19608869
C017803zinc protoporphyrinzinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to TNFRSF1A protein]]]19608869
D019287Zinc SulfateZinc Sulfate results in decreased activity of SRC protein16410015

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004672protein kinase activity-IDA18616680  
GO:0004672protein kinase activity-TAS-  
GO:0004713protein tyrosine kinase activity-EXP1381360  9799234  10861086  11448999  12923167  15735019  
16921024  18697750  20100835  
GO:0004713protein tyrosine kinase activity-IDA16441665  19059439  
GO:0004713protein tyrosine kinase activity-IMP20624904  25425738  
GO:0004713protein tyrosine kinase activity-NAS28386764  
GO:0004713protein tyrosine kinase activity-TAS-  
GO:0004715non-membrane spanning protein tyrosine kinase activity-IBA21873635  
GO:0004715non-membrane spanning protein tyrosine kinase activity-TAS19267251  
GO:0005070SH3/SH2 adaptor activity-TAS9020193  
GO:0005080protein kinase C binding-IEA-  
GO:0005102signaling receptor binding-IBA21873635  
GO:0005102signaling receptor binding-IPI19332538  
GO:0005158insulin receptor binding-IEA-  
GO:0005178integrin binding-TAS19267251  
GO:0005515protein binding-IPI7478590  7537265  8070403  8681387  8849729  9148935  
9162084  9600099  9763511  10521452  10542110  10698938  
10801826  11007774  11013230  11149930  11152665  11483589  
11741929  11923305  11940572  12509223  12857726  14963108  
15143158  15491611  15546919  15557335  15735685  15749833  
15834155  15851033  15866871  16115959  16169070  16273093  
16291744  16374509  16432186  16479011  16511561  16537444  
16636290  16741966  16899217  16964398  16966330  17038317  
17043237  17092689  17094785  17141222  17170700  17178840  
17284441  17318191  17412687  17474147  17491594  17525734  
17921256  17936276  17974954  18070987  18155796  18273061  
18328427  18377662  18464795  18662404  18832467  19122674  
19202075  19262695  19307596  19372587  19419966  19661922  
19665017  19732724  19903481  19910644  20100835  20158519  
20624308  20935677  21034468  21075308  21233420  21278788  
21685945  21725358  21798038  22056988  22402981  22439932  
22581261  23065768  23397142  23564345  23585225  23954233  
24034250  24498420  24658140  24728074  25117710  25241761  
25814554  28054552  
GO:0005524ATP binding-IEA-  
GO:0008022protein C-terminus binding-IPI25425738  
GO:0016301kinase activity-TAS-  
GO:0019899enzyme binding-IPI21724833  
GO:0019900kinase binding-IPI19059439  
GO:0020037heme binding-IDA21036157  
GO:0030331estrogen receptor binding-IEA-  
GO:0031625ubiquitin protein ligase binding-IEA-  
GO:0042169SH2 domain binding-IPI8070403  
GO:0044325ion channel binding-IPI8953041  12538589  
GO:0045296cadherin binding-HDA25468996  
GO:0046875ephrin receptor binding-IPI12925710  
GO:0046934phosphatidylinositol-4,5-bisphosphate 3-kinase activity-TAS-  
GO:0051219phosphoprotein binding-IPI16441665  
GO:0051427hormone receptor binding-IBA21873635  
GO:0070851growth factor receptor binding-IBA21873635  
GO:0070851growth factor receptor binding-IPI16479011  
GO:0071253connexin binding-IEA-  
GO:0097110scaffold protein binding-IPI25006397  
GO ID GO Term Qualifier Evidence PubMed
GO:0001545primary ovarian follicle growth-IEA-  
GO:0002223stimulatory C-type lectin receptor signaling pathway-TAS-  
GO:0007049cell cycle-IEA-  
GO:0007165signal transduction-TAS9020193  10734107  
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway-IBA21873635  
GO:0007172signal complex assembly-TAS9924018  
GO:0007173epidermal growth factor receptor signaling pathway-IBA21873635  
GO:0007173epidermal growth factor receptor signaling pathway-TAS-  
GO:0007179transforming growth factor beta receptor signaling pathway-IMP24036928  
GO:0007229integrin-mediated signaling pathway-IMP24036928  
GO:0007411axon guidance-TAS-  
GO:0008283cell proliferation-IEA-  
GO:0009612response to mechanical stimulus-IEA-  
GO:0009615response to virus-IEA-  
GO:0010447response to acidic pH-IEA-  
GO:0010632regulation of epithelial cell migration-IMP21724833  
GO:0010634positive regulation of epithelial cell migration-IMP18054784  
GO:0010641positive regulation of platelet-derived growth factor receptor signaling pathway-IEA-  
GO:0010907positive regulation of glucose metabolic process-IEA-  
GO:0010954positive regulation of protein processing-IEA-  
GO:0014911positive regulation of smooth muscle cell migration-IEA-  
GO:0016032viral process-IEA-  
GO:0016236macroautophagy-TAS-  
GO:0018105peptidyl-serine phosphorylation-IEA-  
GO:0018108peptidyl-tyrosine phosphorylation-IDA12051764  22732588  
GO:0018108peptidyl-tyrosine phosphorylation-IMP20624904  25425738  
GO:0022407regulation of cell-cell adhesion-IMP21724833  
GO:0030154cell differentiation-IBA21873635  
GO:0030168platelet activation-TAS-  
GO:0030900forebrain development-IEA-  
GO:0031295T cell costimulation-TAS-  
GO:0031648protein destabilization-IEA-  
GO:0031667response to nutrient levels-IEA-  
GO:0031954positive regulation of protein autophosphorylation-IEA-  
GO:0032148activation of protein kinase B activity-IEA-  
GO:0032211negative regulation of telomere maintenance via telomerase-IMP21531765  
GO:0032463negative regulation of protein homooligomerization-IMP19767770  
GO:0032869cellular response to insulin stimulus-IEA-  
GO:0033146regulation of intracellular estrogen receptor signaling pathway-IEA-  
GO:0033625positive regulation of integrin activation-TAS19267251  
GO:0034332adherens junction organization-IEA-  
GO:0034446substrate adhesion-dependent cell spreading-IEA-  
GO:0034614cellular response to reactive oxygen species-IEA-  
GO:0035556intracellular signal transduction-IDA15248232  
GO:0035635entry of bacterium into host cell-TAS-  
GO:0036035osteoclast development-IBA21873635  
GO:0036120cellular response to platelet-derived growth factor stimulus-IEA-  
GO:0038083peptidyl-tyrosine autophosphorylation-IBA21873635  
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis-TAS-  
GO:0042127regulation of cell proliferation-IBA21873635  
GO:0042542response to hydrogen peroxide-IEA-  
GO:0043065positive regulation of apoptotic process-IEA-  
GO:0043066negative regulation of apoptotic process-IMP19767770  
GO:0043114regulation of vascular permeability-TAS19267251  
GO:0043149stress fiber assembly-IMP24036928  
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-IMP19767770  
GO:0043393regulation of protein binding-IEA-  
GO:0043406positive regulation of MAP kinase activity-IEA-  
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity-IEA-  
GO:0045056transcytosis-IEA-  
GO:0045087innate immune response-IBA21873635  
GO:0045124regulation of bone resorption-TAS19267251  
GO:0045453bone resorption-IBA21873635  
GO:0045453bone resorption-ISS-  
GO:0045737positive regulation of cyclin-dependent protein serine/threonine kinase activity-IEA-  
GO:0045892negative regulation of transcription, DNA-templated-IEA-  
GO:0045893positive regulation of transcription, DNA-templated-IEA-  
GO:0046628positive regulation of insulin receptor signaling pathway-IEA-  
GO:0046777protein autophosphorylation-IDA16441665  
GO:0046854phosphatidylinositol phosphorylation-IEA-  
GO:0048010vascular endothelial growth factor receptor signaling pathway-TAS-  
GO:0048011neurotrophin TRK receptor signaling pathway-IEA-  
GO:0048013ephrin receptor signaling pathway-TAS-  
GO:0048477oogenesis-IEA-  
GO:0050715positive regulation of cytokine secretion-IEA-  
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation-IC18054784  
GO:0050847progesterone receptor signaling pathway-IBA21873635  
GO:0050847progesterone receptor signaling pathway-ISS-  
GO:0050900leukocyte migration-TAS-  
GO:0051057positive regulation of small GTPase mediated signal transduction-IMP18541665  
GO:0051385response to mineralocorticoid-IEA-  
GO:0051602response to electrical stimulus-IEA-  
GO:0051895negative regulation of focal adhesion assembly-ISS-  
GO:0051897positive regulation of protein kinase B signaling-IMP19767770  
GO:0051897positive regulation of protein kinase B signaling-TAS-  
GO:0051902negative regulation of mitochondrial depolarization-IMP19767770  
GO:0051974negative regulation of telomerase activity-IMP21531765  
GO:0060065uterus development-IEA-  
GO:0060444branching involved in mammary gland duct morphogenesis-IEA-  
GO:0060491regulation of cell projection assembly-IEA-  
GO:0070374positive regulation of ERK1 and ERK2 cascade-IEA-  
GO:0070555response to interleukin-1-IMP19281832  
GO:0071222cellular response to lipopolysaccharide-IEA-  
GO:0071375cellular response to peptide hormone stimulus-ISS-  
GO:0071393cellular response to progesterone stimulus-ISS-  
GO:0071398cellular response to fatty acid-IEA-  
GO:0071456cellular response to hypoxia-IEA-  
GO:0071498cellular response to fluid shear stress-IEA-  
GO:0071803positive regulation of podosome assembly-IEA-  
GO:0071902positive regulation of protein serine/threonine kinase activity-IDA19059439  
GO:0086098angiotensin-activated signaling pathway involved in heart process-ISS-  
GO:0090263positive regulation of canonical Wnt signaling pathway-IEA-  
GO:0098609cell-cell adhesion-IEA-  
GO:1900182positive regulation of protein localization to nucleus-IEA-  
GO:2000386positive regulation of ovarian follicle development-IEA-  
GO:2000394positive regulation of lamellipodium morphogenesis-IMP18054784  
GO:2000573positive regulation of DNA biosynthetic process-IEA-  
GO:2000641regulation of early endosome to late endosome transport-IMP21724833  
GO:2000811negative regulation of anoikis-IMP22402981  
GO:2001237negative regulation of extrinsic apoptotic signaling pathway-IBA21873635  
GO:2001237negative regulation of extrinsic apoptotic signaling pathway-IMP19767770  
GO:2001243negative regulation of intrinsic apoptotic signaling pathway-IBA21873635  
GO:2001243negative regulation of intrinsic apoptotic signaling pathway-IMP19767770  
GO:2001286regulation of caveolin-mediated endocytosis-IMP21724833  
GO ID GO Term Qualifier Evidence PubMed
GO:0002102podosome-IEA-  
GO:0005634nucleus-IEA-  
GO:0005737cytoplasm-IDA16441665  
GO:0005739mitochondrion-IDA19767770  
GO:0005743mitochondrial inner membrane-IDA12615910  
GO:0005764lysosome-IDA20605918  
GO:0005770late endosome-IDA20605918  
GO:0005829cytosol-IDA19767770  
GO:0005829cytosol-TAS-  
GO:0005884actin filament-IEA-  
GO:0005886plasma membrane-IDA20605918  
GO:0005886plasma membrane-TAS-  
GO:0005901caveola-IDA17848177  
GO:0014069postsynaptic density-IEA-  
GO:0031234extrinsic component of cytoplasmic side of plasma membrane-IBA21873635  
GO:0032587ruffle membrane-IEA-  
GO:0043005neuron projection-IEA-  
GO:0048471perinuclear region of cytoplasm-IEA-  
GO:0070062extracellular exosome-HDA19056867  20458337  
KEGG ID KEGG Term
hsa04012ErbB signaling pathway
hsa04144Endocytosis
hsa04370VEGF signaling pathway
hsa04510Focal adhesion
hsa04520Adherens junction
hsa04530Tight junction
hsa04540Gap junction
hsa04912GnRH signaling pathway
hsa05100Bacterial invasion of epithelial cells
hsa05120Epithelial cell signaling in Helicobacter pylori infection
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-1227986Signaling by ERBB2TAS
R-HSA-1257604PIP3 activates AKT signalingTAS
R-HSA-1266738Developmental BiologyIEA
R-HSA-1266738Developmental BiologyTAS
R-HSA-1280218Adaptive Immune SystemTAS
R-HSA-1295596Spry regulation of FGF signalingTAS
R-HSA-1433557Signaling by SCF-KITTAS
R-HSA-1433557Signaling by SCF-KITIEA
R-HSA-1433559Regulation of KIT signalingTAS
R-HSA-1500931Cell-Cell communicationIEA
R-HSA-157858Gap junction trafficking and regulationTAS
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-1640170Cell CycleTAS
R-HSA-1643685DiseaseTAS
R-HSA-166520Signaling by NTRKsIEA
R-HSA-167044Signalling to RASIEA
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-171007p38MAPK eventsIEA
R-HSA-177929Signaling by EGFRTAS
R-HSA-180292GAB1 signalosomeTAS
R-HSA-186763Downstream signal transductionTAS
R-HSA-186797Signaling by PDGFTAS
R-HSA-187037Signaling by NTRK1 (TRKA)IEA
R-HSA-187687Signalling to ERKsIEA
R-HSA-190236Signaling by FGFRTAS
R-HSA-191647c-src mediated regulation of Cx43 function and closure of gap junctionsTAS
R-HSA-191650Regulation of gap junction activityTAS
R-HSA-194138Signaling by VEGFTAS
R-HSA-194138Signaling by VEGFIEA
R-HSA-194315Signaling by Rho GTPasesTAS
R-HSA-195258RHO GTPase EffectorsTAS
R-HSA-199418Negative regulation of the PI3K/AKT networkTAS
R-HSA-199991Membrane TraffickingTAS
R-HSA-202733Cell surface interactions at the vascular wallTAS
R-HSA-2029480Fcgamma receptor (FCGR) dependent phagocytosisTAS
R-HSA-2029481FCGR activationTAS
R-HSA-210990PECAM1 interactionsTAS
R-HSA-212436Generic Transcription PathwayIEA
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-2219528PI3K/AKT Signaling in CancerTAS
R-HSA-2219530Constitutive Signaling by Aberrant PI3K in CancerTAS
R-HSA-2682334EPH-Ephrin signalingTAS
R-HSA-2682334EPH-Ephrin signalingIEA
R-HSA-354192Integrin alphaIIb beta3 signalingTAS
R-HSA-354194GRB2:SOS provides linkage to MAPK signaling for Integrins TAS
R-HSA-372708p130Cas linkage to MAPK signaling for integrinsTAS
R-HSA-373752Netrin-1 signalingIEA
R-HSA-373752Netrin-1 signalingTAS
R-HSA-373760L1CAM interactionsTAS
R-HSA-375165NCAM signaling for neurite out-growthIEA
R-HSA-376176Signaling by ROBO receptorsIEA
R-HSA-388841Costimulation by the CD28 familyTAS
R-HSA-389356CD28 co-stimulationTAS
R-HSA-389513CTLA4 inhibitory signalingTAS
R-HSA-391160Signal regulatory protein family interactionsIEA
R-HSA-392518Signal amplificationTAS
R-HSA-3928662EPHB-mediated forward signalingTAS
R-HSA-3928662EPHB-mediated forward signalingIEA
R-HSA-3928663EPHA-mediated growth cone collapseTAS
R-HSA-3928663EPHA-mediated growth cone collapseIEA
R-HSA-3928664Ephrin signalingTAS
R-HSA-3928664Ephrin signalingIEA
R-HSA-3928665EPH-ephrin mediated repulsion of cellsTAS
R-HSA-418592ADP signalling through P2Y purinoceptor 1TAS
R-HSA-418885DCC mediated attractive signalingTAS
R-HSA-418885DCC mediated attractive signalingIEA
R-HSA-418886Netrin mediated repulsion signalsIEA
R-HSA-422475Axon guidanceIEA
R-HSA-422475Axon guidanceTAS
R-HSA-428542Regulation of commissural axon pathfinding by SLIT and ROBOIEA
R-HSA-430116GP1b-IX-V activation signallingTAS
R-HSA-437239Recycling pathway of L1TAS
R-HSA-4420097VEGFA-VEGFR2 PathwayTAS
R-HSA-4420097VEGFA-VEGFR2 PathwayIEA
R-HSA-453279Mitotic G1-G1/S phasesTAS
R-HSA-456926Thrombin signalling through proteinase activated receptors (PARs)TAS
R-HSA-5205647MitophagyTAS
R-HSA-5218921VEGFR2 mediated cell proliferationTAS
R-HSA-5607764CLEC7A (Dectin-1) signalingTAS
R-HSA-5621481C-type lectin receptors (CLRs)TAS
R-HSA-5653656Vesicle-mediated transportTAS
R-HSA-5654726Negative regulation of FGFR1 signalingTAS
R-HSA-5654727Negative regulation of FGFR2 signalingTAS
R-HSA-5654732Negative regulation of FGFR3 signalingTAS
R-HSA-5654733Negative regulation of FGFR4 signalingTAS
R-HSA-5654736Signaling by FGFR1TAS
R-HSA-5654738Signaling by FGFR2TAS
R-HSA-5654741Signaling by FGFR3TAS
R-HSA-5654743Signaling by FGFR4TAS
R-HSA-5663202Diseases of signal transductionTAS
R-HSA-5663205Infectious diseaseTAS
R-HSA-5663220RHO GTPases Activate ForminsTAS
R-HSA-5673000RAF activationTAS
R-HSA-5673001RAF/MAP kinase cascadeTAS
R-HSA-5674135MAP2K and MAPK activationTAS
R-HSA-5683057MAPK family signaling cascadesTAS
R-HSA-5684996MAPK1/MAPK3 signalingTAS
R-HSA-6802946Signaling by moderate kinase activity BRAF mutantsTAS
R-HSA-6802948Signaling by high-kinase activity BRAF mutantsTAS
R-HSA-6802949Signaling by RAS mutantsTAS
R-HSA-6802952Signaling by BRAF and RAF fusionsTAS
R-HSA-6802955Paradoxical activation of RAF signaling by kinase inactive BRAFTAS
R-HSA-6802957Oncogenic MAPK signalingTAS
R-HSA-6806834Signaling by METTAS
R-HSA-6811558PI5P, PP2A and IER3 Regulate PI3K/AKT SignalingTAS
R-HSA-69231Cyclin D associated events in G1TAS
R-HSA-69236G1 PhaseTAS
R-HSA-69278Cell Cycle, MitoticTAS
R-HSA-73857RNA Polymerase II TranscriptionIEA
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)IEA
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-76002Platelet activation, signaling and aggregationTAS
R-HSA-76009Platelet Aggregation (Plug Formation)TAS
R-HSA-8853659RET signalingTAS
R-HSA-8874081MET activates PTK2 signalingTAS
R-HSA-8875878MET promotes cell motilityTAS
R-HSA-8876384Listeria monocytogenes entry into host cellsTAS
R-HSA-8876493InlA-mediated entry of Listeria monocytogenes into host cellsTAS
R-HSA-8878159Transcriptional regulation by RUNX3TAS
R-HSA-8878166Transcriptional regulation by RUNX2IEA
R-HSA-8878171Transcriptional regulation by RUNX1IEA
R-HSA-8934593Regulation of RUNX1 Expression and ActivityIEA
R-HSA-8934903Receptor Mediated MitophagyTAS
R-HSA-8940973RUNX2 regulates osteoblast differentiationIEA
R-HSA-8941326RUNX2 regulates bone developmentIEA
R-HSA-8941858Regulation of RUNX3 expression and activityTAS
R-HSA-9006115Signaling by NTRK2 (TRKB)IEA
R-HSA-9006921Integrin signalingTAS
R-HSA-9006925Intracellular signaling by second messengersTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesIEA
R-HSA-9032500Activated NTRK2 signals through FYNIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
19934338EphA2 in the early pathogenesis and progression of non-small cell lung cancer. (2009 Dec)Brannan JMCancer Prev Res (Phila)
29286114Cigarette smoke-induced EGFR activation promotes epithelial mesenchymal migration of human retinal pigment epithelial cells through regulation of the FAK-mediated Syk/Src pathway. (2018 Mar)Park GBMol Med Rep
22240023Nicotine-mediated induction of E-selectin in aortic endothelial cells requires Src kinase and E2F1 transcriptional activity. (2012 Feb 3)Alamanda VBiochem Biophys Res Commun
27784625Nicotine-induced neuroplasticity counteracts the effect of schizophrenia-linked neuregulin 1 signaling on NMDAR function in the rat hippocampus. (2017 Feb)Yamazaki YNeuropharmacology
22923641The ly-6 protein, lynx1, is an endogenous inhibitor of nicotinic signaling in airway epithelium. (2012 Oct 15)Fu XWAm J Physiol Lung Cell Mol Physiol
25007143Pulmonary adenocarcinoma with signet ring cell features: a comprehensive study from 3 distinct patient cohorts. (2014 Dec)Boland JMAm J Surg Pathol
23308043Nicotine induces inhibitor of differentiation-1 in a Src-dependent pathway promoting metastasis and chemoresistance in pancreatic adenocarcinoma. (2012 Dec)Trevino JGNeoplasia
25260978Differential modulation of nicotine-induced gemcitabine resistance by GABA receptor agonists in pancreatic cancer cell xenografts and in vitro. (2014 Sep 27)Banerjee JBMC Cancer
22178655NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCiota/FAK loop. (2012 May 1)Shen JCancer Lett
9839441Fyn, a Src family tyrosine kinase. (1998 Nov)Resh MDInt J Biochem Cell Biol
22891281Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation. (2012 Sep 15)Li FFJ Immunol
25600647beta-arrestin-1 mediates nicotine-induced metastasis through E2F1 target genes that modulate epithelial-mesenchymal transition. (2015 Mar 15)Pillai SCancer Res
25347576Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epithelium. (2015 Jun)Chung SAm J Respir Cell Mol Biol
23053269Evaluation of the pharmacokinetics and safety of bosutinib in patients with chronic hepatic impairment and matched healthy subjects. (2013 Jan)Abbas RCancer Chemother Pharmacol
24684526Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor. (2014 Nov 20)Goldkorn TAntioxid Redox Signal
21618517Expression and pharmacological inhibition of thymidylate synthase and Src kinase in nonsmall cell lung cancer. (2012 Apr 15)Ceppi PInt J Cancer
22614008Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through alpha7nAChR-mediated MUC4 upregulation. (2013 Mar 14)Momi NOncogene
28790817Emerging pharmaceutical therapies for COPD. (2017)Lakshmi SPInt J Chron Obstruct Pulmon Dis
27228072Nicotine-Mediated Regulation of Nicotinic Acetylcholine Receptors in Non-Small Cell Lung Adenocarcinoma by E2F1 and STAT1 Transcription Factors. (2016)Schaal CPLoS One
27157991Severe Reduction in Number and Function of Peripheral T Cells Does Not Afford Protection toward Emphysema and Bronchial Remodeling Induced in Mice by Cigarette Smoke. (2016 Jul)De Cunto GAm J Pathol
22120634p120-catenin modulates airway epithelial cell migration induced by cigarette smoke. (2012 Jan 6)Zhang LBiochem Biophys Res Commun
22165966Gamma-amino butyric acid inhibits the nicotine-imposed stimulatory challenge in xenograft models of non-small cell lung carcinoma. (2012 Feb)Al-Wadei HACurr Cancer Drug Targets
27279347A systems biology and proteomics-based approach identifies SRC and VEGFA as biomarkers in risk factor mediated coronary heart disease. (2016 Jul 19)V AMol Biosyst
26244510A Snack Dietary Pattern Increases the Risk of Hypercholesterolemia in Northern Chinese Adults: A Prospective Cohort Study. (2015)Na LPLoS One
17179996Linkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine dependence. (2007 May)Li MDMol Psychiatry
22791813Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters. (2012 Sep)Al-Wadei MHCarcinogenesis
14569062Nicotine promoted colon cancer growth via epidermal growth factor receptor, c-Src, and 5-lipoxygenase-mediated signal pathway. (2004 Jan)Ye YNJ Pharmacol Exp Ther
11718039[The role of beta-catenin in the repair of the damaged airway epithelium in smoking mice]. (2001 Aug)Li WZhonghua Jie He He Hu Xi Za Zhi
21606196ID1 facilitates the growth and metastasis of non-small cell lung cancer in response to nicotinic acetylcholine receptor and epidermal growth factor receptor signaling. (2011 Jul)Pillai SMol Cell Biol
23146955Chronic nicotine inhibits the therapeutic effects of gemcitabine on pancreatic cancer in vitro and in mouse xenografts. (2013 Mar)Banerjee JEur J Cancer
20354174Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration. (2010 Jun 10)Yao HBlood
26898612Cigarette smoke extract exposure induces EGFR-TKI resistance in EGFR-mutated NSCLC via mediating Src activation and EMT. (2016 Mar)Li DLung Cancer
27506785Histone arginine methylation in cocaine action in the nucleus accumbens. (2016 Aug 23)Damez-Werno DMProc Natl Acad Sci U S A
27612966Acrolein and thiol-reactive electrophiles suppress allergen-induced innate airway epithelial responses by inhibition of DUOX1 and EGFR. (2016 Nov 1)Danyal KAm J Physiol Lung Cell Mol Physiol
19630721Do pharmacological approaches that prevent opioid tolerance target different elements in the same regulatory machinery? (2008 Jun)Garzon JCurr Drug Abuse Rev
24111605Cigarette smoke activates the proto-oncogene c-src to promote airway inflammation and lung tissue destruction. (2014 Mar)Geraghty PAm J Respir Cell Mol Biol
18445113Upregulation of beta-catenin levels in superior frontal cortex of chronic alcoholics. (2008 Jun)Al-Housseini AMAlcohol Clin Exp Res
19046792Differential ErbB receptor expression and intracellular signaling activity in lung adenocarcinomas and squamous cell carcinomas. (2009 Jul)Lopez-Malpartida AVLung Cancer
18844224Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines. (2009 Jan 1)Dasgupta PInt J Cancer
18234883Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia. (2008 Jan 30)Alessandri-Haber NJ Neurosci
26518718Identification of gene markers in the development of smoking-induced lung cancer. (2016 Jan 15)Yang ZGene
17068140Chronic nicotine exposure enhances insulin-induced mitogenic signaling via up-regulation of alpha7 nicotinic receptors in isolated rat aortic smooth muscle cells. (2007 Feb)Wada TEndocrinology
20130484Primary signet-ring carcinoma (SRC) of the lung: a population-based epidemiologic study of 262 cases with comparison to adenocarcinoma of the lung. (2010 Apr)Ou SHJ Thorac Oncol
22537161Nicotine, IFN-gamma and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades. (2012 Apr 26)Kunigal SMol Cancer
24904279The sodium leak channel, NALCN, in health and disease. (2014)Cochet-Bissuel MFront Cell Neurosci
23244430Opioid withdrawal syndrome: emerging concepts and novel therapeutic targets. (2013 Feb 1)Rehni AKCNS Neurol Disord Drug Targets
28818835Src-dependent phosphorylation of mu-opioid receptor at Tyr(336) modulates opiate withdrawal. (2017 Nov)Zhang LEMBO Mol Med
11798907[Effects of cigarette smoke extract on the expression of beta-catenin and tyrosine phosphorylation in airway epithelial cells]. (2001 Apr 10)Chen FZhonghua Yi Xue Za Zhi
22188668Pancreatic cancer cells and normal pancreatic duct epithelial cells express an autocrine catecholamine loop that is activated by nicotinic acetylcholine receptors alpha3, alpha5, and alpha7. (2012 Feb)Al-Wadei MHMol Cancer Res
16441285From blue states to up states: a regional view of NMDA-ethanol interactions. (2006 Feb)Woodward JJAlcohol Clin Exp Res