Gene: SSX2

6757
CT5.2|CT5.2A|HD21|HOM-MEL-40|SSX
SSX family member 2
protein-coding
Xp11.22
Ensembl:ENSG00000241476 MIM:300192 Vega:OTTHUMG00000022697 UniprotKB:Q16385
NC_000023.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TEX360.427
DPEP30.416
NODAL0.408
SCGB3A20.394
TCL1A0.39
CCL220.39
CTAG1B0.385
HOXC110.383
KRTAP10-50.371
TTLL100.361

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
UROC1-0.232
LRRIQ3-0.216
CHAF1A-0.206
GDF10-0.204
TMSB4Y-0.201
NLGN4Y-0.2
EMILIN3-0.2
KDM5D-0.198
ALS2CR12-0.198
LGI3-0.196

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D002104CadmiumCadmium results in decreased expression of SSX2 mRNA24376830
C014347decitabinedecitabine affects the expression of SSX2 mRNA17145863|1824014
C014347decitabinedecitabine results in increased expression of SSX2 mRNA19401350|2038186
D002117CalcitriolCalcitriol results in decreased expression of SSX2 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in decreased expression of SSX2 mRNA21592394
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of SSX2 mRNA24796395
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of SSX2 mRNA26272509
C017947sodium arsenitesodium arsenite results in decreased expression of SSX2 protein21925251
D013739Testosterone[Testosterone co-treated with Calcitriol] results in decreased expression of SSX2 mRNA21592394
D013739TestosteroneTestosterone results in decreased expression of SSX2 mRNA21592394

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003676nucleic acid binding-IEA-  
GO:0005515protein binding-IPI12007189  25416956  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006355regulation of transcription, DNA-templated-NAS7539744  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
16299236Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer. (2005 Nov 15)Gure AOClin Cancer Res