Gene: STAT3

6774
ADMIO|ADMIO1|APRF|HIES
signal transducer and activator of transcription 3
protein-coding
17q21.2
Ensembl:ENSG00000168610 MIM:102582 Vega:OTTHUMG00000150645 UniprotKB:P40763
NG_007370.1
PubMed
ND|AD
42   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.793e-1 (AD)  4.129e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC39A10.917
SHC10.906
MCMBP0.891
LIMK20.882
CHSY10.88
ECE10.875
MOB1A0.875
WDR10.873
MSN0.872
RELA0.869

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.496
OR4F29-0.477
CRH-0.345
ABCC12-0.34
LYPD8-0.328
EDN3-0.319
SMIM18-0.315
NMU-0.314
SLC7A4-0.314
NEUROD6-0.311

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB05959ENMD-1198Small Molecule864668-87-1InvestigationalTarget
ID Drug Name Action PubMed
C0252051,10-phenanthroline"1,10-phenanthroline inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]"10364193
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of STAT3 mRNA"19162173
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of STAT3 mRNA"28903501
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of STAT3 protein"21705713
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of STAT3 protein modified form"21705713
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"CTNNB1 gene mutant form affects the susceptibility to [1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the expression of STAT3 protein]"21705713
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]"16413037
C09724015-deoxy-delta(12,14)-prostaglandin J2"Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]]"16413037
C09724015-deoxy-delta(12,14)-prostaglandin J2"Dithiothreitol inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]]"16413037
C09724015-deoxy-delta(12,14)-prostaglandin J2"Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]]"16413037
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]"12847270
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]"19922793
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]"19922793
C09724015-deoxy-delta(12,14)-prostaglandin J2"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]"19922793
C09724015-deoxy-delta(12,14)-prostaglandin J2"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]"19922793
C09724015-deoxy-delta(12,14)-prostaglandin J2"T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]"19922793
C09724015-deoxy-delta(12,14)-prostaglandin J2"T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]"19922793
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]"12584205
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein]"12584205
C5544281-nitrosocyclohexyl acetate1-nitrosocyclohexyl acetate inhibits the reaction [LIF protein results in increased activity of STAT3 protein]22905257
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [PIK3CA protein mutant form results in increased phosphorylation of STAT3 protein]"21788516
C5740372-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)pyran-4-one"2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)pyran-4-one results in decreased phosphorylation of STAT3 protein"24300195
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of STAT3 mRNA"25614096
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-(3,5-dimethoxystyryl)phenyl acetate affects the phosphorylation of STAT3 protein]"26138072
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]19429262
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Endosulfan affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [IFNG protein results in decreased phosphorylation of STAT3 protein]16427044
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Methoxychlor affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]20008137
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]"19922793
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]"19922793
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]"19922793
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]"19922793
C1202272-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide"2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]"23782265
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of STAT3 mRNA"19114083
C0368372,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone"2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]]"25432964
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased phosphorylation of STAT3 protein"24978599
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased phosphorylation of STAT3 protein"24978599
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased phosphorylation of STAT3 protein"24978599
C5622542'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione"2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased phosphorylation of STAT3 protein"21741372
C5622542'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione"Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased phosphorylation of STAT3 protein]"21741372
C5859122,4-dihydroxy-N-(4-hydroxyphenyl)benzamide"2,4-dihydroxy-N-(4-hydroxyphenyl)benzamide results in decreased phosphorylation of STAT3 protein"24144632
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of STAT3 mRNA"21346803
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IFNG protein results in decreased phosphorylation of STAT3 protein]16427044
C5066982,5-dimethylcelecoxib"2,5-dimethylcelecoxib inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]"16123214
C00799725-hydroxycholesterol25-hydroxycholesterol inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]27052460
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of STAT3 mRNA"21346803
C07699627-hydroxycholesterol27-hydroxycholesterol results in increased phosphorylation of STAT3 protein27856279
C07699627-hydroxycholesterolAcetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]27856279
C07699627-hydroxycholesterolSTAT3 protein promotes the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]27856279
C07699627-hydroxycholesterolSTAT3 protein promotes the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein]27856279
C07699627-hydroxycholesterol27-hydroxycholesterol results in increased phosphorylation of STAT3 protein28739487
C07699627-hydroxycholesterolAcetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]28739487
C07699627-hydroxycholesterolIL6 protein affects the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]28739487
C07699627-hydroxycholesterolstattic inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]28739487
C5706622-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido(2,3-d)pyrimidin-7(8H)-one"2-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido(2,3-d)pyrimidin-7(8H)-one results in decreased phosphorylation of STAT3 protein"23639247
C5188602-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide results in decreased phosphorylation of STAT3 protein"17363558
C5308032-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid methyl amide"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid methyl amide results in decreased phosphorylation of STAT3 protein"17363558
C0130312'-hydroxychalcone2'-hydroxychalcone inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]17320913
C0303702-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone"2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone results in increased expression of STAT3 mRNA"20206263
C5240632-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one"2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one inhibits the reaction [OSM protein results in increased phosphorylation of STAT3 protein]"21548952
C0415253,3',4,5'-tetrahydroxystilbene"3,3',4,5'-tetrahydroxystilbene binds to STAT3 protein"18995957
C0415253,3',4,5'-tetrahydroxystilbene"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Dextran Sulfate results in increased phosphorylation of and results in increased activity of STAT3 protein]"20155626
C0415253,3',4,5'-tetrahydroxystilbene"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA]"18995957
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein"28284859
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form"28284859
C0230353,4,5,3',4'-pentachlorobiphenyl"Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]"28284859
C0230353,4,5,3',4'-pentachlorobiphenyl"Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]"28284859
C0230353,4,5,3',4'-pentachlorobiphenyl"AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]"28284859
C0230353,4,5,3',4'-pentachlorobiphenyl"AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]"28284859
C0230353,4,5,3',4'-pentachlorobiphenyl"fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]"28284859
C0230353,4,5,3',4'-pentachlorobiphenyl"fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]"28284859
C0230353,4,5,3',4'-pentachlorobiphenyl"PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]"28284859
C0230353,4,5,3',4'-pentachlorobiphenyl"PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]"28284859
C0230353,4,5,3',4'-pentachlorobiphenyl"WP1066 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]"28284859
C0350553,4-dihydroxyphenyllactic acid"3,4-dihydroxyphenyllactic acid inhibits the reaction [tert-Butylhydroperoxide results in decreased phosphorylation of STAT3 protein]"29128606
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]17666914
C5240423,5-bis(2-fluorobenzylidene)piperidin-4-one"3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased phosphorylation of STAT3 protein"25725129
C5240423,5-bis(2-fluorobenzylidene)piperidin-4-one"HMGA2 protein inhibits the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased phosphorylation of STAT3 protein]"25725129
C5240423,5-bis(2-fluorobenzylidene)piperidin-4-one"MIR33B mRNA affects the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased phosphorylation of STAT3 protein]"25725129
C0345343,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid"3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid results in decreased phosphorylation of STAT3 protein"21071580
C0179063-dinitrobenzene3-dinitrobenzene results in increased expression of STAT3 mRNA21983209|2284181
C4411283-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate"[3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate co-treated with INS protein] results in increased phosphorylation of STAT3 protein"20075852
C4411283-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate"3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate results in increased phosphorylation of STAT3 protein"20075852
C0020104-(2-aminoethyl)benzenesulfonylfluoride4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]23376140
C0006020014-(3,5-dimethoxystyryl)phenyl acetate"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-(3,5-dimethoxystyryl)phenyl acetate affects the phosphorylation of STAT3 protein]"26138072
C0006020014-(3,5-dimethoxystyryl)phenyl acetate"4-(3,5-dimethoxystyryl)phenyl acetate inhibits the reaction [EGF protein results in increased expression of STAT3 protein]"26138072
C0006020014-(3,5-dimethoxystyryl)phenyl acetate"4-(3,5-dimethoxystyryl)phenyl acetate inhibits the reaction [EGF protein results in increased expression of STAT3 protein modified form]"26138072
C0006020014-(3,5-dimethoxystyryl)phenyl acetate"4-(3,5-dimethoxystyryl)phenyl acetate results in increased phosphorylation of STAT3 protein"26138072
C0006020014-(3,5-dimethoxystyryl)phenyl acetate"4-(3,5-dimethoxystyryl)phenyl acetate results in decreased phosphorylation of STAT3 protein"26138072
C0888604-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]"17028263
C0888604-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Vehicle Emissions results in increased phosphorylation of STAT3 protein]"17028263
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein]16046413
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [arsenic trioxide results in increased phosphorylation of and affects the localization of STAT3 protein]27174766
C5550214-acetylantroquinonol B4-acetylantroquinonol B results in decreased phosphorylation of STAT3 protein26235807
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of STAT3 mRNA19191707
C5843684'-methoxy licoflavanone4'-methoxy licoflavanone results in decreased phosphorylation of and results in decreased activity of STAT3 protein23850732
C1073645,6,7-trimethoxyflavone"5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of STAT3 protein]"24161485
C1073645,6,7-trimethoxyflavone"5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein]"24161485
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of STAT3 protein modified form]]"24064760
C0006253616-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside inhibits the reaction [interferon alfa-2a results in increased phosphorylation of STAT3 protein]29031523
C0006253616-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside inhibits the reaction [Interferon beta-1b results in increased phosphorylation of STAT3 protein]29031523
C0006253616-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside results in increased phosphorylation of STAT3 protein29031523
D000082AcetaminophenAcetaminophen results in increased expression of STAT3 mRNA22230336
D000082AcetaminophenAcetaminophen affects the expression of STAT3 mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of STAT3 mRNA11752693
D000082AcetaminophenAcetaminophen results in increased phosphorylation of STAT3 protein25265579
D000082AcetaminophenMAP3K5 protein affects the reaction [Acetaminophen results in increased expression of STAT3 mRNA]18700144
D000082Acetaminophensaikosaponin inhibits the reaction [Acetaminophen results in increased phosphorylation of STAT3 protein]25265579
D000082AcetaminophenAcetaminophen results in increased expression of STAT3 mRNA17522070
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]]"16413037
D000111AcetylcysteineAcetylcysteine promotes the reaction [cyanidin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]]17320913
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased phosphorylation of STAT3 protein]"21741372
D000111AcetylcysteineAcetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]27856279
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]"28284859
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]"28284859
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of STAT3 protein]24582688
D000111AcetylcysteineAcetylcysteine inhibits the reaction [DDT results in increased phosphorylation of and results in increased expression of STAT3 protein]24820114
D000111AcetylcysteineAcetylcysteine inhibits the reaction [manumycin results in decreased phosphorylation of STAT3 protein]19409983
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]16896058
D000111AcetylcysteineAcetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]17666914
D000111AcetylcysteineAcetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]28739487
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of STAT3 mRNA]23948867
D000111AcetylcysteineAcetylcysteine inhibits the reaction [NSC 680410 results in decreased phosphorylation of STAT3 protein]16481037
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]21912612
D000111AcetylcysteineAllopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]]21912612
D000143AcidsAcids results in increased phosphorylation of STAT3 protein18512153
D000143Acidssorafenib inhibits the reaction [Acids results in increased phosphorylation of STAT3 protein]18512153
D017255AcitretinAcitretin results in decreased expression of STAT3 mRNA16610086
D017255AcitretinAcitretin results in decreased expression of STAT3 protein16610086
D017255AcitretinAcitretin results in decreased expression of STAT3 protein modified form16610086
D000171AcroleinAcrolein inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]16413037|1732091
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of STAT3 mRNA21641981|2894338
C027955aflatoxin G1aflatoxin G1 results in increased phosphorylation of STAT3 protein25445582
C412373AG 1879AG 1879 inhibits the reaction [[cobaltous chloride results in increased activity of SRC protein] which results in increased phosphorylation of STAT3 protein]15735682
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Indican results in increased phosphorylation of STAT3 protein]23639249
C412373AG 1879[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of STAT3 protein]23639249
D000493AllopurinolAllopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]]21912612
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"[alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide co-treated with U 0126] inhibits the reaction [Nicotine promotes the reaction [RELA protein binds to STAT3 protein modified form]]"18448488
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Bile Acids and Salts results in increased expression of and results in increased activity of and results in increased phosphorylation of STAT3 protein]"21127259
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [CSF3 protein results in increased phosphorylation of STAT3 protein]"12393423
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [glycine-extended gastrin 17 affects the localization of STAT3 protein]"16442704
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of STAT3 protein]"19153190
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [IFNA1 protein results in increased phosphorylation of STAT3 protein]"15845643
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 mRNA]"15845643
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Nicotine promotes the reaction [RELA protein binds to STAT3 protein modified form]]"18448488
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]]"17336289
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased phosphorylation of STAT3 protein]]"17336289
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]"17666914
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of STAT3 protein"21503893|2209658
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased expression of STAT3 protein modified form"25896424
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased phosphorylation of and results in decreased activity of STAT3 protein"25061499
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased phosphorylation of and results in decreased expression of STAT3 protein"24587049
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased phosphorylation of STAT3 protein"18592012|2019708
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"[alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased phosphorylation of STAT3 protein] which results in decreased expression of BIRC5 protein"18592012
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"[alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased phosphorylation of STAT3 protein] which results in decreased expression of CCND1 protein"18592012
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"[alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased phosphorylation of STAT3 protein] which results in decreased expression of MYC protein"18592012
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"[alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased phosphorylation of STAT3 protein] which results in decreased expression of PTGS2 protein"18592012
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cyclosporine results in increased phosphorylation of STAT3 protein]"22155090
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of STAT3 mRNA]"22454431
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT3 protein]"22454431
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]"20224768
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]"20008137
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]"22454431
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]"22454431
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of STAT3 protein"21940958
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"[alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of STAT3 protein] which results in decreased expression of SOD2 protein"21940958
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased phosphorylation of STAT3 protein"20224768
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [arsenic trioxide results in increased phosphorylation of STAT3 protein]"27174766
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [CTF1 results in increased expression of STAT3 protein]"16534557
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [CTF1 results in increased expression of STAT3 protein modified form]"19100119
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [CTF1 results in increased phosphorylation of STAT3 protein]"18400235
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of STAT3 protein"16048438
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [LEP protein results in increased phosphorylation of STAT3 protein]"17993459
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of STAT3 protein"14985304
D024502alpha-Tocopherolalpha-Tocopherol results in increased expression of STAT3 mRNA16908007
C000154alpinumisoflavonealpinumisoflavone results in decreased phosphorylation of and results in decreased activity of STAT3 protein23850732
C077990alvocidib[alvocidib co-treated with Bortezomib] results in decreased phosphorylation of and results in decreased activity of STAT3 protein15039284
C077990alvocidibalvocidib results in decreased expression of STAT3 mRNA21239698
C103505AM 251AM 251 results in decreased expression of STAT3 mRNA16500647
D000643Ammonium ChlorideAmmonium Chloride affects the expression of STAT3 mRNA16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of STAT3 mRNA"22863853
C530884anacetrapibanacetrapib results in increased phosphorylation of STAT3 protein25617244
C030419andrographolideandrographolide results in decreased activity of STAT3 protein23845849
C053442annonacinannonacin results in decreased phosphorylation of STAT3 protein21840388
D000941Antigens[ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of STAT3 mRNA28935500
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of STAT3 mRNA24449571
D047310ApigeninApigenin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein]20153296
D047310ApigeninApigenin results in decreased phosphorylation of STAT3 protein27468969
C071942arctigeninarctigenin results in decreased phosphorylation of STAT3 protein25380086
C071942arctigeninQuercetin promotes the reaction [arctigenin results in decreased phosphorylation of STAT3 protein]25380086
C071942arctigenin"arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of and affects the localization of STAT3 protein]"21426947
D001151ArsenicAcetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of STAT3 protein]24582688
D001151ArsenicArsenic affects the methylation of STAT3 gene25304211
D001151ArsenicArsenic analog results in increased phosphorylation of STAT3 protein24582688
D001151ArsenicArsenic results in increased expression of STAT3 mRNA27838757
D001151ArsenicArsenic results in increased phosphorylation of STAT3 protein25559853
D001151ArsenicSTAT3 protein affects the reaction [Arsenic results in increased expression of VEGFA protein]25559853
D001151ArsenicSTAT3 results in decreased susceptibility to Arsenic15116095
D001151ArsenicArsenic affects the phosphorylation of STAT3 protein27289040
D001152ArsenicalsArsenicals affects the phosphorylation of STAT3 protein23255093
D001152ArsenicalsArsenicals results in increased expression of STAT3 mRNA23255093
D001152ArsenicalsMAPK8 mutant form affects the reaction [Arsenicals affects the phosphorylation of STAT3 protein]23255093
D001152Arsenicalsstattic affects the reaction [Arsenicals affects the phosphorylation of STAT3 protein]23255093
C050510arsenic trichloridearsenic trichloride affects the phosphorylation of STAT3 protein24434654
C050510arsenic trichloridearsenic trichloride results in increased phosphorylation of STAT3 protein22696236
C050510arsenic trichloridepyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein]22696236
C050510arsenic trichlorideSTAT3 mutant form inhibits the reaction [arsenic trichloride results in increased expression of RIOX2 protein]24434654
C050510arsenic trichlorideSTAT3 mutant form inhibits the reaction [arsenic trichloride results in increased expression of VEGFA protein]22696236
C050510arsenic trichlorideMAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein]22696236
C050510arsenic trichlorideMAPK9 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein]22696236
C006632arsenic trioxidearsenic trioxide affects the methylation of STAT3 promoter26046465
C006632arsenic trioxidearsenic trioxide inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]12492118
C006632arsenic trioxide[arsenic trioxide results in decreased activity of NOTCH1 protein] which results in decreased phosphorylation of and results in decreased activity of STAT3 protein23542114
C006632arsenic trioxidearsenic trioxide results in decreased expression of and results in decreased phosphorylation of STAT3 protein23382965
C006632arsenic trioxidearsenic trioxide results in decreased expression of STAT3 mRNA23382965
C006632arsenic trioxidearsenic trioxide results in decreased expression of STAT3 protein23382965
C006632arsenic trioxidearsenic trioxide results in decreased phosphorylation of and results in decreased activity of STAT3 protein17121903
C006632arsenic trioxidearsenic trioxide results in decreased phosphorylation of STAT3 protein25196641
C006632arsenic trioxidearsenic trioxide results in decreased phosphorylation of STAT3 protein28454374
C006632arsenic trioxide4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [arsenic trioxide results in increased phosphorylation of and affects the localization of STAT3 protein]27174766
C006632arsenic trioxide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [arsenic trioxide results in increased phosphorylation of STAT3 protein]"27174766
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of and affects the localization of STAT3 protein27174766
C006632arsenic trioxidepyrazolanthrone inhibits the reaction [arsenic trioxide results in increased phosphorylation of and affects the localization of STAT3 protein]27174766
C015001arsenitearsenite results in increased expression of STAT3 mRNA18191166
D017639Asbestos, Amosite"Asbestos, Amosite results in increased activity of STAT3 protein"29112861
D017639Asbestos, Amosite"Asbestos, Amosite results in increased expression of STAT3 mRNA"29112861
D017639Asbestos, Amosite"Asbestos, Amosite results in increased expression of STAT3 protein modified form"27083413
D017636Asbestos, Amphibole"Asbestos, Amphibole results in increased expression of STAT3 protein modified form"27083413
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]16896058
D001241AspirinAspirin results in decreased expression of STAT3 mRNA11906190
D001241AspirinAspirin results in decreased expression of STAT3 protein modified form19595669
D001241AspirinIL6 protein inhibits the reaction [Aspirin results in decreased expression of STAT3 protein modified form]19595669
D001241AspirinAspirin results in decreased phosphorylation of STAT3 protein20886344
D001310Auranofin[Auranofin co-treated with IL6 protein] results in decreased phosphorylation of STAT3 protein20542334
D001310AuranofinAuranofin results in decreased expression of STAT3 protein modified form20542334
D001374Azacitidine[Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein18443271
C099015azaspiraneazaspirane inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]15705788
D001379AzathioprineAzathioprine inhibits the reaction [RAC1 protein binds to STAT3 protein]12697733
C545606AZD 1480AZD 1480 results in decreased phosphorylation of STAT3 protein21138246
C545606AZD 1480AZD 1480 results in decreased phosphorylation of STAT3 protein21486047
C517975AZD 6244AZD 6244 promotes the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]23782265
C547126AZM551248AZM551248 results in increased expression of STAT3 mRNA22323515
D001397Azoxymethane[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein25026504
D001397Azoxymethaneisoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein]25026504
D001397Azoxymethane[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein19028472
D001397AzoxymethaneMelatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein]19028472
C018003benzo(a)pyrene-3,6-quinone"benzo(a)pyrene-3,6-quinone results in increased phosphorylation of STAT3 protein"19166869
D019817Benzoic AcidBenzoic Acid analog inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]26088127
D019817Benzoic AcidBenzoic Acid analog inhibits the reaction [STAT3 protein binds to BCL2 promoter]26088127
D019817Benzoic AcidBenzoic Acid analog inhibits the reaction [STAT3 protein binds to BIRC5 promoter]26088127
D019817Benzoic AcidBenzoic Acid analog inhibits the reaction [STAT3 protein binds to NOS2 promoter]26088127
D019817Benzoic AcidBenzoic Acid analog results in decreased phosphorylation of and results in decreased activity of STAT3 protein26088127
D019817Benzoic AcidBenzoic Acid analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]]26088127
D019817Benzoic AcidBenzoic Acid analog inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]26088127
D019817Benzoic AcidBenzoic Acid analog results in decreased phosphorylation of and results in decreased activity of STAT3 protein26088127
D001564Benzo(a)pyreneBenzo(a)pyrene affects the activity of STAT3 protein20624995
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of STAT3 mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of STAT3 mRNA22228805
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of STAT3 mRNA"20382639
C048081beraprost"beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein]"28887131
D004958Estradiol"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]]"17336289
D004958Estradiol"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased phosphorylation of STAT3 protein]]"17336289
D004958EstradiolEstradiol inhibits the reaction [LIF protein results in increased activity of STAT3 protein]14975756
D004958EstradiolEstradiol results in increased phosphorylation of STAT3 protein17336289
D004958Estradiol[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]17336289
D004958EstradiolRaloxifene Hydrochloride inhibits the reaction [Estradiol results in increased phosphorylation of STAT3 protein]17336289
D004958EstradiolESR1 protein promotes the reaction [Estradiol results in increased expression of STAT3 mRNA]25210133
D004958EstradiolEstradiol results in increased expression of STAT3 mRNA15289156|1662759
D001622BetaineBetaine promotes the reaction [Isoproterenol results in increased phosphorylation of STAT3 protein]25080425
C044887beta-methylcholinebeta-methylcholine affects the expression of STAT3 mRNA21179406
D001647Bile Acids and Salts"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Bile Acids and Salts results in increased expression of and results in increased activity of and results in increased phosphorylation of STAT3 protein]"21127259
D001647Bile Acids and SaltsBile Acids and Salts results in increased activity of and results in increased phosphorylation of STAT3 protein21127259
D001647Bile Acids and SaltsBile Acids and Salts results in increased expression of STAT3 protein21127259
D001647Bile Acids and SaltsBile Acids and Salts results in increased expression of STAT3 protein modified form21127259
D001647Bile Acids and SaltsBile Acids and Salts results in increased localization of STAT3 protein21127259
D001647Bile Acids and Salts[NR1H4 gene mutant form results in increased susceptibility to Bile Acids and Salts] which results in increased activity of STAT3 protein24091600
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]]24496235
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein]24496235
C006780bisphenol Abisphenol A affects the expression of STAT3 mRNA21786754
C006780bisphenol A2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
C006780bisphenol A[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]14975756
C006780bisphenol Abisphenol A promotes the reaction [LIF protein results in increased activity of STAT3 protein]14975756
C006780bisphenol Abisphenol A results in increased expression of STAT3 mRNA21909620|2927551
C006780bisphenol Abisphenol A results in increased phosphorylation of and affects the localization of STAT3 protein28466560
C006780bisphenol Abisphenol A results in increased phosphorylation of STAT3 protein22343039|2434919
C006780bisphenol AGPER1 protein affects the reaction [bisphenol A results in increased phosphorylation of STAT3 protein]28466560
C006780bisphenol AIL6 protein affects the reaction [bisphenol A results in increased phosphorylation of STAT3 protein]28466560
C006780bisphenol Apyrazolanthrone inhibits the reaction [bisphenol A results in increased phosphorylation of STAT3 protein]24349194
C006780bisphenol ASTAT3 results in increased susceptibility to bisphenol A21909620
C006780bisphenol ATamoxifen inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
C006780bisphenol A[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in decreased phosphorylation of STAT3 protein25128825
C006780bisphenol Atyrphostin AG 1478 inhibits the reaction [bisphenol A results in increased expression of STAT3 mRNA]21909620
C006780bisphenol Abisphenol A affects the methylation of STAT3 gene26542749
C006780bisphenol Abisphenol A affects the methylation of STAT3 promoter27334623
C006780bisphenol A[bisphenol A co-treated with Dietary Fats] results in increased expression of STAT3 mRNA23493373
C006780bisphenol Abisphenol A results in increased phosphorylation of and results in increased activity of STAT3 protein16860915|1721026
C006780bisphenol ATamoxifen inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased activity of STAT3 protein]16860915
C006780bisphenol Abisphenol A affects the phosphorylation of STAT3 protein15642633
C006780bisphenol Abisphenol A results in increased phosphorylation of STAT3 protein15242752
C006780bisphenol Abisphenol A affects the expression of STAT3 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of STAT3 mRNA25181051|2596372
C006780bisphenol Abisphenol A results in increased methylation of STAT3 gene28505145
C006780bisphenol ACurcumin inhibits the reaction [bisphenol A results in increased expression of STAT3 mRNA]25963729
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA28628672
D000069286Bortezomib[alvocidib co-treated with Bortezomib] results in decreased phosphorylation of and results in decreased activity of STAT3 protein15039284
D000069286BortezomibBortezomib promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]17505005
D000069286BortezomibBortezomib promotes the reaction [Curcumin results in decreased phosphorylation of STAT3 protein]19383353
D000069286BortezomibBortezomib results in increased expression of and results in increased phosphorylation of STAT3 protein24627483
D000069286Bortezomib[resveratrol co-treated with Bortezomib] results in decreased phosphorylation of STAT3 protein17164350
C000595192BP-1-102BP-1-102 analog inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]26088127
C000595192BP-1-102BP-1-102 analog inhibits the reaction [STAT3 protein binds to BCL2 promoter]26088127
C000595192BP-1-102BP-1-102 analog inhibits the reaction [STAT3 protein binds to BIRC5 promoter]26088127
C000595192BP-1-102BP-1-102 analog inhibits the reaction [STAT3 protein binds to NOS2 promoter]26088127
C000595192BP-1-102BP-1-102 analog results in decreased phosphorylation of and results in decreased activity of STAT3 protein26088127
C000595192BP-1-102BP-1-102 results in decreased phosphorylation of and results in decreased activity of STAT3 protein26088127
C000595192BP-1-102BP-1-102 analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]]26088127
C000595192BP-1-102BP-1-102 analog inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]26088127
C000595192BP-1-102BP-1-102 analog results in decreased phosphorylation of and results in decreased activity of STAT3 protein26088127
C000595192BP-1-102BP-1-102 results in decreased phosphorylation of and results in decreased activity of STAT3 protein26088127
C544847BP-PM6BP-PM6 results in decreased phosphorylation of STAT3 protein21486047
C048491butaprostbutaprost inhibits the reaction [[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein]21268125
C048491butaprostbutaprost results in increased phosphorylation of STAT3 protein21268125
D019328Buthionine SulfoximineButhionine Sulfoximine promotes the reaction [Chalcone inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]]17320913
D019328Buthionine SulfoximineButhionine Sulfoximine results in increased activity of STAT3 protein11841787
D019328Buthionine SulfoximineButhionine Sulfoximine results in increased expression of STAT3 mRNA11841787
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]17028263
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [Vanadates results in increased phosphorylation of STAT3 protein]17028263
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [Vehicle Emissions results in increased phosphorylation of STAT3 protein]17028263
D020122tert-Butylhydroperoxide"3,4-dihydroxyphenyllactic acid inhibits the reaction [tert-Butylhydroperoxide results in decreased phosphorylation of STAT3 protein]"29128606
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased phosphorylation of STAT3 protein29128606
C584509C646 compoundC646 compound results in decreased expression of STAT3 mRNA26191083
D002101Cacodylic Acid[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA23192986
D002104CadmiumCadmium inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]16843830
D002104CadmiumCadmium inhibits the reaction [CNTF protein affects the localization of STAT3 protein]16843830
D002104CadmiumCadmium inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]16843830
D002104CadmiumCadmium results in increased phosphorylation of STAT3 protein21783819
D002104CadmiumSB 203580 inhibits the reaction [Cadmium results in increased phosphorylation of STAT3 protein]21783819
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]16843830
D019256Cadmium Chloride2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]19429262
D019256Cadmium Chloride"2,6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]"19635391
D019256Cadmium ChlorideCadmium Chloride affects the localization of STAT3 protein modified form19429262
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [CNTF protein affects the localization of STAT3 protein]16843830
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]16843830
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]19635391
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein19429262
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of STAT3 protein27634459
D019256Cadmium Chloridecatalase-polyethylene glycol inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]19429262
D019256Cadmium Chloridediphenyleneiodonium inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]19429262
D019256Cadmium Chloridepyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]19429262
D019256Cadmium ChlorideThioctic Acid inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]19635391
D019256Cadmium Chloride4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]23376140
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of STAT3 mRNA]23948867
D019256Cadmium ChlorideCadmium Chloride promotes the reaction [EGFR protein binds to STAT3 protein]23376140
D019256Cadmium ChlorideCadmium Chloride promotes the reaction [STAT3 protein binds to SRC protein]23376140
D019256Cadmium Chloride[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]] which results in increased phosphorylation of STAT3 protein23376140
D019256Cadmium Chloride[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]] which results in increased phosphorylation of STAT3 protein] which results in increased expression of MT223376140
D019256Cadmium Chloride[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein23376140
D019256Cadmium Chloride[[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein] promotes the reaction [STAT3 protein binds to STAT3 protein]23376140
D019256Cadmium ChlorideCadmium Chloride results in increased expression of STAT3 mRNA23948867
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein23376140
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of STAT3 protein23948867
D019256Cadmium Chloridegefitinib inhibits the reaction [Cadmium Chloride results in increased expression of STAT3 mRNA]23948867
D019256Cadmium Chloridegefitinib inhibits the reaction [Cadmium Chloride results in increased phosphorylation of STAT3 protein]23948867
D019256Cadmium Chloride[MAPK1 protein co-treated with MAPK3 protein] affects the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]23376140
D019256Cadmium Chloride[[tyrphostin AG 1478 results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]23376140
D019256Cadmium ChlorideCadmium Chloride results in increased expression of STAT3 mRNA25993096
D019256Cadmium ChlorideCAT protein inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]23376140
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester inhibits the reaction [Cyclosporine results in increased phosphorylation of STAT3 protein]22155090
C059041calyculin A[calyculin A co-treated with LIF protein] results in increased phosphorylation of STAT3 protein22142222
D002185Cannabidiol"Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and results in increased activity of STAT3 protein]"19910459
D002211CapsaicinBortezomib promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]17505005
D002211CapsaicinCapsaicin affects the localization of STAT3 protein17505005
D002211CapsaicinCapsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]17505005
D002211CapsaicinCapsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein17505005
D002211Capsaicinpervanadate inhibits the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]17505005
D002211CapsaicinThalidomide promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]17505005
D002211CapsaicinCapsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]19285962
D002211CapsaicinCapsaicin results in increased phosphorylation of STAT3 protein16788306
D002211CapsaicinSR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of STAT3 protein]16788306
D002220CarbamazepineCarbamazepine affects the expression of STAT3 mRNA24752500
D002235CarbofuranCarbofuran results in increased expression of STAT3 mRNA22240977|2898298
D002251Carbon Tetrachloride"2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]]"25432964
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased activity of STAT3 protein12730884|1283000
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased phosphorylation of STAT3 protein14999682|1939372
D002251Carbon TetrachlorideDinoprostone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]]25432964
D002251Carbon TetrachlorideIL6 protein affects the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]14999682
D002251Carbon TetrachlorideIL6ST protein affects the reaction [Carbon Tetrachloride results in increased activity of STAT3 protein]12830005
D002251Carbon TetrachlorideLEP protein affects the reaction [Carbon Tetrachloride results in increased activity of STAT3 protein]12730884
D002251Carbon TetrachlorideOSM protein affects the reaction [IL6 protein affects the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]]14999682
D002251Carbon TetrachloridePTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]25432964
D002251Carbon TetrachlorideSC 560 inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]25432964
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of STAT3 mRNA16239168
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased activity of STAT3 protein17009398
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of STAT3 mRNA17522070|2606254
D002251Carbon TetrachlorideRutin inhibits the reaction [Carbon Tetrachloride results in increased expression of STAT3 mRNA]26062544
D002259Carbonyl Cyanide p-TrifluoromethoxyphenylhydrazoneSTAT3 protein affects the susceptibility to Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone20224768
D002273CarcinogensCarcinogens results in increased expression of STAT3 mRNA16316942
C070295catalase-polyethylene glycolcatalase-polyethylene glycol inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]19429262
D000068579Celecoxib[Celecoxib results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein21268125
D002509CephaloridineCephaloridine results in increased expression of STAT3 mRNA18500788
D002108CeruletideIL6 protein inhibits the reaction [(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]]26390243
D002108Ceruletide(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]26390243
D002108Ceruletide[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein26390243
C062876cetrorelixcetrorelix results in decreased phosphorylation of STAT3 protein21062912
D002599ChalconeButhionine Sulfoximine promotes the reaction [Chalcone inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]]17320913
D002599ChalconeChalcone inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]17320913
D017338CladribineCladribine results in increased phosphorylation of STAT3 protein21679466
C007020chlorophyllinchlorophyllin inhibits the reaction [Lipopolysaccharides results in increased activity of STAT3 protein]16275627
D002737ChloropreneChloroprene results in increased expression of STAT3 mRNA23125180
C074702chromium hexavalent ionchromium hexavalent ion promotes the reaction [STAT3 protein binds to MIR21 promoter]27323401
C074702chromium hexavalent ionchromium hexavalent ion results in increased activity of and results in increased phosphorylation of STAT3 protein27323401
C074702chromium hexavalent ionchromium hexavalent ion results in increased expression of STAT3 protein25448439
C074702chromium hexavalent ionchromium hexavalent ion results in increased phosphorylation of and results in increased activity of and affects the localization of STAT3 protein alternative form17078813
C074702chromium hexavalent ionLCK protein affects the reaction [chromium hexavalent ion results in increased phosphorylation of STAT3 protein alternative form]17078813
C074702chromium hexavalent ionLuteolin inhibits the reaction [chromium hexavalent ion results in increased expression of STAT3 protein]25448439
C074702chromium hexavalent ionSTAT3 protein affects the reaction [chromium hexavalent ion results in increased expression of MIR21 mRNA]27323401
C418118CI 1044CI 1044 results in increased expression of STAT3 mRNA17569694
C039671ciglitazone"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]"19922793
C039671ciglitazone"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]"19922793
C039671ciglitazoneciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]19922793
C039671ciglitazoneciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]19922793
C039671ciglitazoneT 0070907 inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]19922793
C039671ciglitazoneT 0070907 inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]19922793
C007095cobaltiprotoporphyrincobaltiprotoporphyrin affects the phosphorylation of STAT3 protein25171655
C007095cobaltiprotoporphyrinNFE2L2 protein affects the reaction [cobaltiprotoporphyrin affects the phosphorylation of STAT3 protein]25171655
C007095cobaltiprotoporphyrinSTAT3 protein promotes the reaction [cobaltiprotoporphyrin results in increased expression of ZFP36 mRNA]24095726
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]24810525
C007095cobaltiprotoporphyrincobaltiprotoporphyrin results in increased phosphorylation of STAT3 protein22237591
C007095cobaltiprotoporphyrinzinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]24810525
C018021cobaltous chlorideAG 1879 inhibits the reaction [[cobaltous chloride results in increased activity of SRC protein] which results in increased phosphorylation of STAT3 protein]15735682
C018021cobaltous chloride[cobaltous chloride results in increased activity of SRC protein] promotes the reaction [[HIF1A protein binds to STAT3 protein modified form] which binds to VEGFA promoter]15735682
C018021cobaltous chloride[cobaltous chloride results in increased activity of SRC protein] promotes the reaction [[[HIF1A protein binds to STAT3 protein modified form] which binds to VEGFA promoter] binds to [APEX1 protein binds to CREBBP promoter]]15735682
C018021cobaltous chloride[cobaltous chloride results in increased activity of SRC protein] which results in increased phosphorylation of STAT3 protein15735682
D005576ColforsinColforsin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]23782265
D005576Colforsinflavone promotes the reaction [Colforsin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]]23782265
D005576Colforsinresveratrol promotes the reaction [Colforsin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]]23782265
D005576ColforsinRolipram promotes the reaction [Colforsin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]]23782265
C055786columbaminecolumbamine inhibits the reaction [CSF2 protein results in increased phosphorylation of STAT3 protein]23124089
D003300CopperCopper results in increased expression of STAT3 mRNA16391388
D003300Copper[Thiosemicarbazones binds to Copper] which results in increased expression of STAT3 protein20931265
D019327Copper SulfateCopper Sulfate inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]16896058
D019327Copper SulfateCopper Sulfate results in increased expression of STAT3 mRNA19549813
D019327Copper Sulfate[ferrous sulfate co-treated with Copper Sulfate] promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]10364193
C113861corosolic acidcorosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]26513295
C113861corosolic acidcorosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]26513295
D003375CoumestrolCoumestrol results in decreased expression of STAT3 mRNA19167446
C494620CPS 11CPS 11 results in decreased phosphorylation of STAT3 protein15858615
C494622CPS 49CPS 49 results in decreased phosphorylation of STAT3 protein15858615
C551994crizotinib[[crizotinib results in decreased phosphorylation of MET protein] which results in increased expression of HGF protein] which results in increased phosphorylation of STAT3 protein22683780
C551994crizotinibcrizotinib results in decreased phosphorylation of STAT3 protein22034911|2255334
C551994crizotinibMET gene mutant form promotes the reaction [crizotinib results in decreased phosphorylation of STAT3 protein]22729845
C041246cucurbitacin Bcucurbitacin B results in decreased phosphorylation of and results in decreased activity of STAT3 protein24316209
C041246cucurbitacin BSTAT3 protein affects the reaction [cucurbitacin B results in decreased expression of CEBPA mRNA]24316209
C041246cucurbitacin BSTAT3 protein affects the reaction [cucurbitacin B results in decreased expression of PPARG mRNA]24316209
C041246cucurbitacin BSTAT3 protein affects the susceptibility to cucurbitacin B24316209
C041246cucurbitacin B[WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin B24316209
C038106cucurbitacin Icucurbitacin I inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of STAT3 protein]19153190
C038106cucurbitacin Icucurbitacin I results in decreased activity of STAT3 protein24316209
C038106cucurbitacin ISTAT3 protein affects the susceptibility to cucurbitacin I24316209
C038106cucurbitacin I[WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin I24316209
C038106cucurbitacin Icucurbitacin I results in decreased activity of STAT3 protein20052772
C029892cupric chloridecupric chloride results in increased expression of STAT3 protein21641295
C029892cupric chloridecupric chloride results in increased expression of STAT3 protein19616320
D003471CuprizoneCuprizone results in increased expression of STAT3 mRNA26577399|2752363
D003474CurcuminBortezomib promotes the reaction [Curcumin results in decreased phosphorylation of STAT3 protein]19383353
D003474CurcuminCurcumin inhibits the reaction [IFNG protein results in increased expression of and results in increased phosphorylation of STAT3 protein]16959222
D003474CurcuminCurcumin inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]17666914
D003474CurcuminCurcumin results in decreased expression of STAT3 mRNA20816778
D003474CurcuminCurcumin results in decreased expression of STAT3 protein16959222
D003474CurcuminCurcumin results in decreased phosphorylation of STAT3 protein19383353
D003474CurcuminCurcumin results in increased phosphorylation of STAT3 protein25822711
D003474CurcuminCurcumin inhibits the reaction [bisphenol A results in increased expression of STAT3 mRNA]25963729
D003474CurcuminCurcumin results in decreased expression of STAT3 mRNA25963729
D003474CurcuminCurcumin results in decreased expression of STAT318462866
C038459curdlancurdlan results in increased expression of STAT3 mRNA23543010
C017154cyanidinAcetylcysteine promotes the reaction [cyanidin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]]17320913
D003520CyclophosphamideCyclophosphamide results in increased phosphorylation of STAT3 protein19625377
D016572Cyclosporine"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cyclosporine results in increased phosphorylation of STAT3 protein]"22155090
D016572Cyclosporinecaffeic acid phenethyl ester inhibits the reaction [Cyclosporine results in increased phosphorylation of STAT3 protein]22155090
D016572CyclosporineCyclosporine results in increased expression of STAT3 protein27585667
D016572CyclosporineCyclosporine results in increased phosphorylation of and affects the localization of STAT3 protein23958496
D016572CyclosporineCyclosporine results in increased phosphorylation of STAT3 protein22155090|2395849
D016572Cyclosporineethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of STAT3 protein]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of STAT3 protein]27585667
D016572CyclosporineCyclosporine inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]19299911
D016572CyclosporineCyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein]19299911
C072247cyclo(Trp-Asp-Pro-Val-Leu)cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Oxygen results in increased phosphorylation of STAT3 protein]25203536
D015638Cytochalasin DCytochalasin D deficiency results in decreased activity of and affects the localization of STAT3 protein28086195
C411602dalcetrapibdalcetrapib results in increased phosphorylation of STAT3 protein25617244
D000069439DasatinibDasatinib results in decreased phosphorylation of STAT3 protein20682659|2382558
D000069439Dasatinib[EGFR gene mutant form results in increased susceptibility to Dasatinib] which results in decreased phosphorylation of STAT3 protein16740687
D003634DDTAcetylcysteine inhibits the reaction [DDT results in increased phosphorylation of and results in increased expression of STAT3 protein]24820114
D003634DDTDDT affects the localization of STAT3 protein24820114
D003634DDTDDT results in increased phosphorylation of and results in increased expression of STAT3 protein24820114
D003634DDTINCB018424 inhibits the reaction [DDT results in increased phosphorylation of STAT3 protein]24820114
D003634DDTWP1066 inhibits the reaction [DDT results in increased phosphorylation of STAT3 protein]24820114
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of STAT3 mRNA24317228
C014347decitabinedecitabine results in decreased expression of STAT3 protein19732952
C014347decitabine"decitabine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of STAT3 protein]"24440346
C107676deguelindeguelin metabolite results in increased activity of STAT3 protein19139008
C107676deguelindeguelin results in increased activity of STAT3 protein19139008
D013759DronabinolDronabinol results in decreased phosphorylation of STAT3 protein23727458
D013759DronabinolDronabinol results in decreased expression of STAT3 mRNA17578508
D003703DemecolcineDemecolcine results in increased expression of STAT3 mRNA23649840
C007262deoxynivalenol"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of STAT3 mRNA]"22454431
C007262deoxynivalenol"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT3 protein]"22454431
C007262deoxynivalenoldeoxynivalenol results in increased expression of STAT3 mRNA22454431
C007262deoxynivalenoldeoxynivalenol results in increased phosphorylation of STAT3 protein22454431
C007262deoxynivalenolstattic inhibits the reaction [deoxynivalenol results in increased expression of STAT3 mRNA]22454431
C007262deoxynivalenolstattic inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT3 protein]22454431
C007262deoxynivalenoldeoxynivalenol results in increased expression of STAT3 mRNA23326479
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of STAT3 mRNA]27941970
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA28628672
D003907DexamethasoneDexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein]12957465
D016264Dextran Sulfate"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Dextran Sulfate results in increased phosphorylation of and results in increased activity of STAT3 protein]"20155626
D016264Dextran Sulfate[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein25026504
D016264Dextran SulfateDextran Sulfate results in increased expression of STAT3 protein26074695
D016264Dextran SulfateDextran Sulfate results in increased phosphorylation of and results in increased activity of STAT3 protein20155626
D016264Dextran Sulfateisoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein]25026504
D016264Dextran Sulfateresveratrol inhibits the reaction [Dextran Sulfate results in increased expression of STAT3 protein]26074695
D016264Dextran Sulfateresveratrol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of and results in increased activity of STAT3 protein]20155626
D016264Dextran Sulfate[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein19028472
D016264Dextran SulfateMelatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein]19028472
D003958DiamideDiamide affects the localization of STAT3 protein10364193
D003973DiatrizoateDiatrizoate affects the expression of STAT3 protein modified form21036957
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of STAT3 mRNA17361019|2126653
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of STAT3 mRNA21266533
D003994BucladesineSTAT3 gene mutant form affects the reaction [IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC protein]]26064446
D002945CisplatinCisplatin results in decreased activity of STAT3 protein20106947
D002945CisplatinCisplatin results in increased expression of STAT3 mRNA27392435
D002945CisplatinNicotine inhibits the reaction [Cisplatin results in decreased activity of STAT3 protein]20106947
D002945Cisplatin[Piroxicam co-treated with Cisplatin] results in decreased expression of STAT3 mRNA21858171
D002945Cisplatin[Quercetin results in increased susceptibility to Cisplatin] which results in decreased phosphorylation of STAT3 protein25611565
D002945CisplatinSTAT3 protein results in decreased susceptibility to Cisplatin20106947|2154941
D002945CisplatinSTAT3 results in decreased susceptibility to Cisplatin21909139
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in decreased activity of STAT3 protein27589886
D0199003,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer"[3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer binds to and results in increased activity of OPRK1 protein] which results in increased phosphorylation of STAT3 protein"18385270
D004008DiclofenacDiclofenac affects the expression of STAT3 mRNA24752500
D004008DiclofenacDiclofenac results in increased expression of STAT3 mRNA23506792
D004008DiclofenacDiclofenac results in increased expression of STAT3 mRNA22285467|2693455
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in decreased expression of STAT3 mRNA26924002
D018119StavudineStavudine results in decreased expression of STAT3 mRNA18299183
D004041Dietary Fats[bisphenol A co-treated with Dietary Fats] results in increased expression of STAT3 mRNA23493373
D004041Dietary FatsDietary Fats inhibits the reaction [LEP protein results in increased phosphorylation of STAT3 protein]22276206
D004041Dietary FatsDietary Fats results in increased expression of STAT3 protein27417254
D004041Dietary Fats"[methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate co-treated with Dietary Fats] results in decreased expression of STAT3 protein"25637688
D004041Dietary Fats"methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate inhibits the reaction [Dietary Fats results in increased expression of STAT3 protein]"27417254
D004052DiethylnitrosamineDexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein]12957465
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein12957465
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of STAT3 mRNA15289156
D004054DiethylstilbestrolDiethylstilbestrol results in decreased phosphorylation of STAT3 protein15242752
D002117CalcitriolCalcitriol results in increased expression of STAT319603526
C042080diisodecyl phthalatediisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]27871981
C042080diisodecyl phthalateMelatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]]27871981
C024629dimethyl phthalatedimethyl phthalate affects the expression of STAT3 mRNA26924002
D004147DioxinsDioxins affects the expression of STAT3 mRNA20463971
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]19429262
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]20523355
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [THPO protein results in increased phosphorylation of STAT3 protein]20523355
D004229Dithiothreitol"Dithiothreitol inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]]"16413037
C067311docetaxel[docetaxel co-treated with epigallocatechin gallate co-treated with Quercetin] results in decreased expression of and results in decreased phosphorylation of STAT3 protein25655047
C067311docetaxeldocetaxel promotes the reaction [[epigallocatechin gallate co-treated with Quercetin] results in decreased phosphorylation of STAT3 protein]25655047
C067311docetaxeldocetaxel results in decreased phosphorylation of STAT3 protein25655047
C067311docetaxel[epigallocatechin gallate co-treated with Quercetin] promotes the reaction [docetaxel results in decreased phosphorylation of STAT3 protein]25655047
D004281Docosahexaenoic AcidsDocosahexaenoic Acids results in decreased expression of STAT3 protein modified form22285823
D004317DoxorubicinDoxorubicin results in increased expression of STAT3 mRNA16001973
D004317DoxorubicinDoxorubicin results in increased expression of STAT3 protein17920763
D004317DoxorubicinSTAT3 protein affects the susceptibility to Doxorubicin17920763
D004317DoxorubicinDoxorubicin results in decreased expression of STAT3 mRNA10618415
D004317DoxorubicinDoxorubicin results in increased phosphorylation of STAT3 protein24812279
D004317Doxorubicin[[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of STAT3 mRNA21040762
D004317DoxorubicinSTAT3 gene mutant form promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]24812279
D004317DoxorubicinSTAT3 gene mutant form promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]24812279
D004317DoxorubicinSTAT3 gene mutant form promotes the reaction [Doxorubicin results in increased expression of XRCC5 protein]24812279
D004317DoxorubicinSTAT3 gene mutant form promotes the reaction [Doxorubicin results in increased expression of XRCC6 protein]24812279
D004317DoxorubicinSTAT3 gene mutant form results in increased susceptibility to Doxorubicin15781265|2481227
D004317Doxorubicin[STAT3 gene mutant form results in increased susceptibility to Doxorubicin] which results in increased activity of CASP3 protein24812279
D004317Doxorubicin[STAT3 gene mutant form results in increased susceptibility to Doxorubicin] which results in increased cleavage of PARP1 protein24812279
D004317Doxorubicin[STAT3 gene mutant form results in increased susceptibility to Doxorubicin] which results in increased expression of XRCC5 protein24812279
D004317Doxorubicin[STAT3 gene mutant form results in increased susceptibility to Doxorubicin] which results in increased expression of XRCC6 protein24812279
D004317DoxorubicinSTAT3 protein promotes the reaction [Doxorubicin results in increased expression of NPPA mRNA]10618415
D004317DoxorubicinSTAT3 protein results in decreased susceptibility to Doxorubicin11524388
D004317DoxorubicinSTAT3 protein results in increased susceptibility to Doxorubicin10618415
D004317DoxorubicinTRP53 mutant form inhibits the reaction [Doxorubicin results in increased phosphorylation of STAT3 protein]24812279
C509867E804 bisindoleE804 bisindole results in decreased activity of STAT3 protein23107598
C561722EGFR tyrosine kinase inhibitor 324674EGFR tyrosine kinase inhibitor 324674 inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]24627483
D015118Eicosapentaenoic AcidEicosapentaenoic Acid results in decreased expression of STAT3 protein modified form22285823
D004610Ellagic AcidEllagic Acid results in decreased expression of STAT3 mRNA20816778
D004610Ellagic AcidEllagic Acid results in increased expression of STAT3 mRNA12002526
D004642EmodinEmodin affects the localization of STAT3 protein23848338
D004642EmodinEmodin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]23848338
D004642EmodinEmodin results in decreased phosphorylation of and results in decreased activity of STAT3 protein23848338
D004642Emodinpervanadate inhibits the reaction [Emodin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]23848338
D004642EmodinPTPN6 mutant form inhibits the reaction [Emodin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]23848338
D004656EnalaprilEnalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA]19958114
D004656EnalaprilEnalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 protein]19958114
D004726Endosulfan2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Endosulfan affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
D004726Endosulfan[Endosulfan affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]14975756
D004726Endosulfan[Endosulfan affects the activity of ESR2 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]14975756
D004726EndosulfanEndosulfan promotes the reaction [LIF protein results in increased activity of STAT3 protein]14975756
D004726EndosulfanTamoxifen inhibits the reaction [[Endosulfan affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
C026066enterotoxin A, Staphylococcal"enterotoxin A, Staphylococcal results in increased phosphorylation of and results in increased activity of STAT3 protein"26738536
C031818enterotoxin B, staphylococcal"enterotoxin B, staphylococcal results in increased expression of STAT3 mRNA"25556216
C118739entinostatentinostat results in increased expression of STAT3 mRNA27188386
D004791Enzyme InhibitorsEnzyme Inhibitors inhibits the reaction [Phenylpropanolamine results in increased expression of STAT3 protein modified form]24792324
D004791Enzyme InhibitorsEnzyme Inhibitors promotes the reaction [LIF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]22366233
C045651epigallocatechin gallate[docetaxel co-treated with epigallocatechin gallate co-treated with Quercetin] results in decreased expression of and results in decreased phosphorylation of STAT3 protein25655047
C045651epigallocatechin gallatedocetaxel promotes the reaction [[epigallocatechin gallate co-treated with Quercetin] results in decreased phosphorylation of STAT3 protein]25655047
C045651epigallocatechin gallate[epigallocatechin gallate co-treated with Quercetin] promotes the reaction [docetaxel results in decreased phosphorylation of STAT3 protein]25655047
C045651epigallocatechin gallate[epigallocatechin gallate co-treated with Quercetin] results in decreased expression of and results in decreased phosphorylation of STAT3 protein25655047
C045651epigallocatechin gallateepigallocatechin gallate results in decreased activity of STAT3 protein22348037
C045651epigallocatechin gallateepigallocatechin gallate results in decreased expression of STAT3 mRNA20816778|2234803
C045651epigallocatechin gallateepigallocatechin gallate results in decreased expression of STAT3 protein22348037
C045651epigallocatechin gallateepigallocatechin gallate results in decreased expression of STAT3 protein modified form22348037
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride results in increased phosphorylation of STAT3 protein23894143
D000069347Erlotinib HydrochlorideNiclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased phosphorylation of STAT3 protein]23894143
D000069347Erlotinib Hydrochloride[Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased phosphorylation of STAT3 protein]] which results in increased susceptibility to Erlotinib Hydrochloride23894143
D000069347Erlotinib HydrochlorideSTAT3 mRNA results in decreased susceptibility to Erlotinib Hydrochloride23125191
D000069347Erlotinib HydrochlorideSTAT3 mutant form results in increased susceptibility to Erlotinib Hydrochloride23894143
D004918Erythromycin EstolateErythromycin Estolate results in increased expression of STAT3 mRNA17522070
D004967EstrogensEstrogens inhibits the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]26631322
D004967EstrogensSOCS3 mutant form inhibits the reaction [Estrogens inhibits the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]]26631322
D000431EthanolEthanol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 protein]20052772
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of STAT3 mRNA16174780
D005013EthosuximideEthosuximide inhibits the reaction [APP protein modified form results in decreased expression of STAT3 mRNA]26420483
D005013EthosuximideEthosuximide results in increased expression of STAT3 mRNA26420483
C507035ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylateethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of STAT3 protein]27585667
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of STAT3 mRNA23649840
D005038EthylnitrosoureaEthylnitrosourea results in decreased phosphorylation of STAT3 protein27725143
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of STAT3 mRNA27776689
C020748ferrous sulfate[ferrous sulfate co-treated with Copper Sulfate] promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]10364193
C017875fisetinfisetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein]20153296
C043562flavoneflavone inhibits the reaction [IL6 protein promotes the reaction [STAT3 protein results in increased expression of CCL2]]23782265
C043562flavoneflavone inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]23782265
C043562flavoneflavone promotes the reaction [Colforsin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]]23782265
C548901FLLL 31FLLL 31 results in decreased phosphorylation of and results in decreased activity of STAT3 protein20215512
C548902FLLL 32FLLL 32 inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of and affects the localization of STAT3 protein]20818158
C548902FLLL 32FLLL 32 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]20215512|2057616
C548902FLLL 32FLLL 32 results in decreased activity of STAT3 protein21109950
C548902FLLL 32FLLL 32 results in decreased phosphorylation of and results in decreased activity of STAT3 protein20215512|2071290
C548902FLLL 32FLLL 32 results in decreased phosphorylation of STAT3 protein20576164
D0150732-AcetylaminofluoreneDexamethasone inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein]12957465
D0150732-Acetylaminofluorene[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased activity of STAT3 protein12957465
D016650Fluorescein-5-isothiocyanatediisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]27871981
D016650Fluorescein-5-isothiocyanateFluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein27871981
D016650Fluorescein-5-isothiocyanateMelatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]]27871981
D005472FluorouracilFluorouracil results in decreased phosphorylation of STAT3 protein18161298|1820525
D005472FluorouracilFluorouracil results in increased expression of STAT3 mRNA16557594
D005472FluorouracilSTAT3 protein affects the susceptibility to Fluorouracil15682485|1573073
D005557FormaldehydeFormaldehyde results in increased expression of STAT3 mRNA23649840
D005632FructoseFructose results in decreased phosphorylation of STAT3 protein23533474
D005632FructoseFructose results in increased phosphorylation of STAT3 protein22426011
D005632FructoseQuercetin inhibits the reaction [Fructose results in decreased phosphorylation of STAT3 protein]23533474
D005632FructoseQuercetin inhibits the reaction [Fructose results in increased phosphorylation of STAT3 protein]22426011
D005632FructoseRutin inhibits the reaction [Fructose results in increased phosphorylation of STAT3 protein]22426011
C070081fulvestrant"fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]"28284859
C070081fulvestrant"fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]"28284859
D005688Galactosamine"beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein]"28887131
D005688Galactosamine"[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein"28887131
D005688Galactosamine"ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein]"28887131
C037032galangingalangin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein]20153296
C416043galiellalactonegaliellalactone results in decreased activity of STAT3 protein24631022
C419708gefitinibgefitinib inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]19318490
C419708gefitinibgefitinib inhibits the reaction [EGF results in increased phosphorylation of STAT3 protein]21787763
C419708gefitinibgefitinib inhibits the reaction [Cadmium Chloride results in increased expression of STAT3 mRNA]23948867
C419708gefitinibgefitinib inhibits the reaction [Cadmium Chloride results in increased phosphorylation of STAT3 protein]23948867
C056507gemcitabinegemcitabine results in decreased activity of STAT3 protein22348037
D019833GenisteinGenistein inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]10364193
D019833GenisteinGenistein results in decreased expression of STAT3 mRNA20816778
D019833GenisteinGenistein results in decreased expression of STAT3 mRNA21048042
D019833GenisteinGenistein results in increased expression of STAT3 mRNA15289156
D005839GentamicinsGentamicins results in increased expression of STAT3 mRNA22061828
D005897GlafenineGlafenine results in increased expression of STAT3 mRNA24136188
D005947Glucose"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of STAT3 protein modified form]]"24064760
D005947GlucoseGlucose results in increased expression of STAT3 protein24064760
D005947GlucoseGlucose results in increased expression of STAT3 protein modified form24064760
D005947Glucoseresveratrol inhibits the reaction [Glucose results in increased expression of STAT3 protein modified form]24064760
D005947GlucoseIL6 protein inhibits the reaction [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] results in decreased phosphorylation of STAT3 protein]21940958
D005947Glucose[[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein]21940958
D005947Glucose[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] results in decreased phosphorylation of STAT3 protein21940958
D005947GlucoseSTAT3 gene mutant form inhibits the reaction [IL22 protein results in decreased abundance of Glucose]26064446
D005947Glucosecobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]24810525
D005947GlucoseGlucose results in decreased phosphorylation of STAT3 protein24810525
D005947GlucoseHMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]24810525
D005947Glucose[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA23421680
D005947Glucose[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 protein23421680
D005947GlucosePropofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]24810525
D005947Glucoseresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA]23421680
D005947Glucoseresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 protein]23421680
D005947GlucoseSTAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]24810525
D005947GlucoseSTAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]]24810525
D005947GlucoseSTAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]24810525
D005947Glucosezinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]24810525
D005947Glucosezinc protoporphyrin inhibits the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]24810525
D005978Glutathione"Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]]"16413037
D005978GlutathioneGlutathione inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]16896058
D005978GlutathioneSTAT3 protein affects the abundance of Glutathione20224768
C086854glycine-extended gastrin 17"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [glycine-extended gastrin 17 affects the localization of STAT3 protein]"16442704
C086854glycine-extended gastrin 17"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of STAT3 protein]"19153190
C086854glycine-extended gastrin 17cucurbitacin I inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of STAT3 protein]19153190
C086854glycine-extended gastrin 17glycine-extended gastrin 17 affects the localization of STAT3 protein16442704
C086854glycine-extended gastrin 17glycine-extended gastrin 17 results in increased phosphorylation of and results in increased activity of STAT3 protein19153190
C086854glycine-extended gastrin 17STAT3 protein affects the reaction [glycine-extended gastrin 17 results in increased expression of BCL2L1 protein]19153190
C086854glycine-extended gastrin 17STAT3 protein affects the reaction [glycine-extended gastrin 17 results in increased expression of BIRC5 protein]19153190
D006046Gold[Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA22155353
D006046GoldGold results in increased expression of STAT3 mRNA22155353
C473027GW 3965GW 3965 inhibits the reaction [IL6 protein results in increased expression of STAT3 protein modified form]27052460
D0193071-(5-Isoquinolinesulfonyl)-2-Methylpiperazine1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT3 protein]11882386
D006221HalothaneHalothane results in increased expression of and results in increased phosphorylation of STAT3 protein24598351
D006221HalothaneHalothane results in increased expression of STAT3 mRNA24598351
C001335hexachlorobutadienehexachlorobutadiene results in increased expression of STAT3 mRNA21905055
D018738HexamethoniumHexamethonium inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488|2010694
D017313FenretinideFenretinide results in increased expression of STAT3 mRNA28973697
C062018HU 2114-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein]16046413
C062018HU 211HU 211 results in increased phosphorylation of STAT3 protein16046413
C062018HU 211Pertussis Toxin inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein]16046413
C062018HU 211rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein]16046413
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein]15748169
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]16843830
D006861Hydrogen Peroxide"1,10-phenanthroline inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]"10364193
D006861Hydrogen Peroxide[ferrous sulfate co-treated with Copper Sulfate] promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]10364193
D006861Hydrogen PeroxideGenistein inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]10364193
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [CNTF protein affects the localization of STAT3 protein]15748169
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]15748169
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]19635391
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [oxophenylarsine affects the localization of STAT3 protein]10364193
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of and affects the localization of STAT3 protein10364193
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of STAT3 protein17028263
D006861Hydrogen PeroxideHydrogen Peroxide results in increased ubiquitination of STAT3 protein24657799
D006861Hydrogen Peroxideoxophenylarsine promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]10364193
D006861Hydrogen PeroxideVanadates promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]10364193
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein]15748169
D006877Hydroxamic AcidsHydroxamic Acids analog inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]26088127
D006877Hydroxamic AcidsHydroxamic Acids analog results in decreased phosphorylation of and results in decreased activity of STAT3 protein26088127
D006877Hydroxamic AcidsHydroxamic Acids analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]]26088127
D006877Hydroxamic AcidsHydroxamic Acids analog inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]26088127
D006877Hydroxamic AcidsHydroxamic Acids analog results in decreased phosphorylation of and results in decreased activity of STAT3 protein26088127
C056493imiquimodimiquimod results in increased expression of STAT3 mRNA26149470
C540383INCB018424INCB018424 inhibits the reaction [DDT results in increased phosphorylation of STAT3 protein]24820114
D007200Indican[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Indican results in increased phosphorylation of STAT3 protein]23639249
D007200IndicanIndican results in increased phosphorylation of and results in increased activity of STAT3 protein23639249
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA28628672
D007213Indomethacinbutaprost inhibits the reaction [[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein]21268125
D007213IndomethacinDinoprostone inhibits the reaction [[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein]21268125
D007213Indomethacin[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein21268125
C554043interferon alfa-2a6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside inhibits the reaction [interferon alfa-2a results in increased phosphorylation of STAT3 protein]29031523
C554043interferon alfa-2ainterferon alfa-2a results in increased phosphorylation of STAT3 protein29031523
D000068576Interferon beta-1b6-hydroxy-3-O-methylkaempferol 6-O-glucopyranoside inhibits the reaction [Interferon beta-1b results in increased phosphorylation of STAT3 protein]29031523
D000068576Interferon beta-1bInterferon beta-1b results in increased phosphorylation of STAT3 protein29031523
C057937iomeproliomeprol affects the expression of STAT3 protein modified form21036957
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of STAT3 mRNA28628672
C040920isoliquiritigeninisoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein]25026504
D007545IsoproterenolIsoproterenol results in increased expression of STAT3 mRNA21335049
D007545IsoproterenolBetaine promotes the reaction [Isoproterenol results in increased phosphorylation of STAT3 protein]25080425
D007545IsoproterenolCyclosporine inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]19299911
D007545IsoproterenolIsoproterenol affects the localization of STAT3 protein19299911
D007545IsoproterenolIsoproterenol results in increased expression of STAT319299911
D007545IsoproterenolIsoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein19299911
D007545IsoproterenolIsoproterenol results in increased phosphorylation of STAT3 protein25080425
D007545IsoproterenolVerapamil inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]19299911
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [[IL6 protein co-treated with IL6R protein] promotes the reaction [STAT3 protein modified form results in increased expression of SOCS3 mRNA]]24657799
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [STAT3 protein modified form results in increased expression of MYC mRNA]24657799
C561695(+)-JQ1 compoundIL6 protein inhibits the reaction [(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]]26390243
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [[KRAS mutant form co-treated with TRP53 mutant form] results in increased phosphorylation of STAT3 protein]26390243
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]26390243
C410337K 7174K 7174 results in increased expression of STAT3 mRNA24086573
C526229kurarinolkurarinol inhibits the reaction [STAT3 protein binds to BCL2L1 promoter]24997323
C526229kurarinolkurarinol results in decreased phosphorylation of STAT3 protein24997323
C526229kurarinolSTAT3 protein inhibits the reaction [kurarinol results in increased activity of CASP3 protein]24997323
C526229kurarinolkurarinol inhibits the reaction [STAT3 protein binds to BCL2L1 promoter]24997323
C526229kurarinolkurarinol results in decreased phosphorylation of STAT3 protein24997323
C008261lead acetatelead acetate results in increased phosphorylation of STAT3 protein26542248
C045463leflunomideleflunomide results in increased expression of STAT3 mRNA28988120
D064704LevofloxacinLevofloxacin results in increased expression of STAT3 mRNA24136188
C118451LFM A13LFM A13 inhibits the reaction [PIK3CA protein mutant form results in increased phosphorylation of STAT3 protein]21788516
C482199lipopolysaccharide, E coli O55-B5"beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein]"28887131
C482199lipopolysaccharide, E coli O55-B5"Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and results in increased activity of STAT3 protein]"19910459
C482199lipopolysaccharide, E coli O55-B5"decitabine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of STAT3 protein]"24440346
C482199lipopolysaccharide, E coli O55-B5"DNMT1 mutant form inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of STAT3 protein]"24440346
C482199lipopolysaccharide, E coli O55-B5"[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein"28887131
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and results in increased activity of STAT3 protein"19910459
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of STAT3 protein"24440346|2565184
C482199lipopolysaccharide, E coli O55-B5"ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein]"28887131
C482199lipopolysaccharide, E coli O55-B5"resveratrol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of STAT3 protein]"25651848
C482199lipopolysaccharide, E coli O55-B5"SOCS1 mutant form inhibits the reaction [DNMT1 mutant form inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of STAT3 protein]]"24440346
C482199lipopolysaccharide, E coli O55-B5"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of STAT3 mRNA"18930950
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of STAT3 mRNA"11578593
C482199lipopolysaccharide, E coli O55-B5"pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of STAT3 mRNA]"11578593
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein"26298005
C440499lipopolysaccharide, Escherichia coli O111 B4"Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein]"26298005
C440499lipopolysaccharide, Escherichia coli O111 B4"[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased degradation of STAT3 protein modified form"19549798
C440499lipopolysaccharide, Escherichia coli O111 B4"5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of STAT3 protein]"24161485
C440499lipopolysaccharide, Escherichia coli O111 B4"5,6,7-trimethoxyflavone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein]"24161485
C440499lipopolysaccharide, Escherichia coli O111 B4"arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of and affects the localization of STAT3 protein]"21426947
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 affects the localization of STAT3 protein"24161485
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of and affects the localization of STAT3 protein"21426947
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein"21469130|2416148
D008070LipopolysaccharidesLipopolysaccharides results in increased activity of STAT3 protein21586572
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of and results in increased activity of STAT3 protein21135123
D008070Lipopolysaccharides[Nicotine co-treated with Lipopolysaccharides] results in increased phosphorylation of STAT3 protein21606497
D008070Lipopolysaccharideschlorophyllin inhibits the reaction [Lipopolysaccharides results in increased activity of STAT3 protein]16275627
D008070LipopolysaccharidesIFNAR1 protein affects the reaction [Lipopolysaccharides results in increased activity of STAT3 protein]21586572
D008070LipopolysaccharidesIL10 protein affects the reaction [resveratrol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]]25576658
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of STAT3 protein22118570
D008070Lipopolysaccharides[Lipopolysaccharides results in increased activity of JAK2 protein] which results in increased activity of STAT3 protein24486434
D008070LipopolysaccharidesLipopolysaccharides results in increased activity of STAT3 protein21586572|2159595
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of STAT3 mRNA10975854|1732100
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of and results in increased activity of STAT3 protein21396905
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of STAT3 protein21262334|2159595
D008070Lipopolysaccharideslycorine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]22155741
D008070LipopolysaccharidesMAPKAPK2 protein affects the reaction [Lipopolysaccharides results in increased activity of STAT3 protein]21586572
D008070LipopolysaccharidesMAPKAPK3 protein affects the reaction [MAPKAPK2 protein affects the reaction [Lipopolysaccharides results in increased activity of STAT3 protein]]21586572
D008070LipopolysaccharidesMelatonin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]22225513
D008070Lipopolysaccharidespraeruptorin C inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]22083490
D008070Lipopolysaccharidespraeruptorin E inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]22083490
D008070Lipopolysaccharidesresveratrol inhibits the reaction [[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of STAT3 protein]22118570
D008070Lipopolysaccharidesresveratrol inhibits the reaction [Lipopolysaccharides results in increased activity of STAT3 protein]22118570
D008070Lipopolysaccharidesresveratrol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]25576658
D008070LipopolysaccharidesSTAT3 gene mutant form results in increased susceptibility to Lipopolysaccharides15781265
D008070LipopolysaccharidesSTAT3 protein promotes the reaction [[Lipopolysaccharides co-treated with Nicotine] results in increased expression of HMOX1 mRNA]24095726
D008070LipopolysaccharidesSTAT3 protein promotes the reaction [[Lipopolysaccharides co-treated with Nicotine] results in increased expression of ZFP36 mRNA]24095726
D008070LipopolysaccharidesSTAT3 protein promotes the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]24095726
D008070LipopolysaccharidesSTAT3 protein promotes the reaction [Nicotine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]24095726
D008070LipopolysaccharidesSTAT3 results in increased susceptibility to Lipopolysaccharides25429137
D008070Lipopolysaccharideswithaferin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of STAT3 protein]21396905
D008070Lipopolysaccharides"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]"12584205
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of STAT3 protein12584205
D008070Lipopolysaccharidesrosiglitazone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]12584205
D008070Lipopolysaccharides[TNF protein co-treated with IL1B protein co-treated with IFNG protein co-treated with Lipopolysaccharides] results in increased expression of STAT3 mRNA20816778
D018021Lithium ChlorideLithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein22493441
D018021Lithium ChlorideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]22493441
C549232LLL12 compoundLLL12 compound inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]21109950
C549232LLL12 compoundLLL12 compound results in decreased activity of STAT3 protein21109950
C549232LLL12 compoundLLL12 compound results in decreased phosphorylation of STAT3 protein23333246
D008120Lobeline[Lobeline binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]] inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488
D008120LobelineLobeline inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]20106947
D047311LuteolinLuteolin inhibits the reaction [chromium hexavalent ion results in increased expression of STAT3 protein]25448439
D047311LuteolinLuteolin promotes the reaction [Paclitaxel results in decreased phosphorylation of STAT3 protein]24525192
D047311LuteolinLuteolin results in decreased phosphorylation of STAT3 protein24525192
D047311LuteolinPaclitaxel promotes the reaction [Luteolin results in decreased phosphorylation of STAT3 protein]24525192
C015329lycopenelycopene results in increased expression of STAT3 mRNA16886892
C015330lycorinelycorine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]22155741
C530478LYR 71LYR 71 inhibits the reaction [CCL5 protein promotes the reaction [STAT3 protein binds to MMP9 promoter]]18985009
C530478LYR 71LYR 71 inhibits the reaction [CCL5 protein results in increased expression of STAT3 protein modified form]18985009
C530478LYR 71LYR 71 results in decreased expression of STAT3 protein modified form18985009
C530478LYR 71LYR 71 results in decreased phosphorylation of STAT3 protein18985009
D008344Maneb[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA23963992
D008344ManebMelatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA]23963992
D008344ManebSilymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA]23963992
C054474manumycinAcetylcysteine inhibits the reaction [manumycin results in decreased phosphorylation of STAT3 protein]19409983
C054474manumycinmanumycin results in decreased phosphorylation of STAT3 protein19409983
C412811maslinic acidmaslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]26513295
C412811maslinic acidmaslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]26513295
D009637MasoprocolMasoprocol results in decreased phosphorylation of STAT3 protein19503098
C540278MDV 3100MDV 3100 promotes the reaction [Niclosamide results in decreased phosphorylation of and results in decreased activity of STAT3 protein]25970160
C540278MDV 3100Niclosamide inhibits the reaction [STAT3 protein results in decreased susceptibility to MDV 3100]25970160
C540278MDV 3100STAT3 protein results in decreased susceptibility to MDV 310025970160
D008550MelatoninMelatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]]27871981
D008550MelatoninMelatonin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]22225513
D008550MelatoninMelatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA]23963992
D008550MelatoninMelatonin results in increased phosphorylation of STAT3 protein21342247
D008550MelatoninSTAT3 protein results in increased susceptibility to Melatonin21342247
D008550MelatoninMelatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein]19028472
D008555MelittenMelitten results in decreased phosphorylation of STAT3 protein22027265
D008555MelittenTNFRSF10A protein affects the reaction [Melitten results in decreased phosphorylation of STAT3 protein]22027265
D008555MelittenTNFRSF21 protein affects the reaction [Melitten results in decreased phosphorylation of STAT3 protein]22027265
D008555MelittenTNFRSF25 protein affects the reaction [Melitten results in decreased phosphorylation of STAT3 protein]22027265
D008555MelittenMelitten inhibits the reaction [[IL6 protein co-treated with IL6R protein] results in increased expression of STAT3 mRNA]21354845
D008555MelittenMelitten inhibits the reaction [[IL6 protein co-treated with IL6R protein] results in increased phosphorylation of and results in increased activity of STAT3 protein]21354845
C545385MequindoxMequindox results in increased expression of STAT3 mRNA21146578
D008627Mercuric ChlorideMercuric Chloride affects the expression of STAT3 mRNA20353558
D008627Mercuric ChlorideAcetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]16896058
D008627Mercuric ChlorideAscorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]16896058
D008627Mercuric ChlorideGlutathione inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]16896058
D008627Mercuric ChlorideMercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]16896058
D008627Mercuric ChlorideMercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]19635391
D008627Mercuric ChlorideThioctic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]19635391
D008727MethotrexateMethotrexate results in decreased expression of STAT3 mRNA24449571
D008731Methoxychlor2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Methoxychlor affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
D008731Methoxychlor[Methoxychlor affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]14975756
D008731Methoxychlor[Methoxychlor affects the activity of ESR2 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]14975756
D008731MethoxychlorMethoxychlor promotes the reaction [LIF protein results in increased activity of STAT3 protein]14975756
D008731MethoxychlorTamoxifen inhibits the reaction [[Methoxychlor affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
C445068methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate"methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate results in decreased phosphorylation of STAT3 protein"17363558
C445068methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate"[methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate co-treated with Dietary Fats] results in decreased expression of STAT3 protein"25637688
C445068methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate"methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate inhibits the reaction [Dietary Fats results in increased expression of STAT3 protein]"27417254
C005219methyl cellosolvemethyl cellosolve results in increased expression of STAT3 mRNA19643169
D008748Methylcholanthrene"[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of STAT3 mRNA"25926378
C054634methyllycaconitine[methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488
C054634methyllycaconitinemethyllycaconitine results in decreased phosphorylation of STAT3 protein25396421
D008767Methylmercury CompoundsMethylmercury Compounds promotes the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]23845766
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of STAT3 mRNA23649840
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein26648565
D0156551-Methyl-4-phenylpyridiniumRTN4 protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein]26648565
D0156551-Methyl-4-phenylpyridiniumSirolimus inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein]26648565
D008777MethyltestosteroneMethyltestosterone results in increased expression of STAT3 mRNA29191790
D008779Methylthiouracil"Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT3 protein]"26298005
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in decreased phosphorylation of STAT3 protein]18453621
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]]16534557
D015735MifepristoneMifepristone affects the localization of STAT3 protein modified form19439560
D015735MifepristoneMifepristone results in increased expression of STAT3 mRNA19439560
D008898MimosineMimosine results in increased phosphorylation of STAT3 protein25469848
C020300monomethylarsonic acid[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA23192986
C406082monomethylarsonous acidmonomethylarsonous acid affects the activity of STAT3 protein20045430
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased expression of STAT3 mRNA22108045
C406082monomethylarsonous acidmonomethylarsonous acid results in increased activity of STAT3 protein22015448
C517284monomethyl phthalatemonomethyl phthalate results in decreased expression of STAT3 mRNA26924002
D009020MorphineMorphine results in increased phosphorylation of STAT3 protein18385270
C057451morusinmorusin results in decreased phosphorylation of and affects the localization of STAT3 protein25476160
C057451morusinmorusin results in decreased phosphorylation of STAT3 protein25476160
D009151Mustard GasMustard Gas results in increased expression of STAT3 mRNA18955075
C040015myricetinmyricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA]18995957
C040015myricetinmyricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]18995957
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]22493441
C510788N4-(2,2-dimethyl-3-oxo-4H-pyrid(1,4)oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine"N4-(2,2-dimethyl-3-oxo-4H-pyrid(1,4)oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine results in decreased phosphorylation of STAT3 protein"25487280
D037742Nanotubes, Carbon"[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of STAT3 mRNA"25926378
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of STAT3 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased activity of STAT3 protein"29112861
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of STAT3 mRNA"25554681|2562005
C000621033napabucasinnapabucasin results in decreased expression of STAT3 mRNA25605917
C073873naphtho(1,2-b)furan-4,5-dione"naphtho(1,2-b)furan-4,5-dione results in decreased phosphorylation of STAT3 protein"20197088
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of STAT3 mRNA15913567
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein27853831
D0150581-Naphthylisothiocyanatepirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein]27853831
D0150581-NaphthylisothiocyanatePPARA protein affects the reaction [pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein]]27853831
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of STAT3 mRNA17522070
C005273naringeninnaringenin results in decreased phosphorylation of STAT3 protein27468969
C005273naringeninnaringenin inhibits the reaction [IL6 protein promotes the reaction [STAT3 protein results in increased expression of CCL2]]23782265
C005273naringeninnaringenin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]23782265
C005274naringinnaringin affects the expression of STAT3 mRNA25117567
C005274naringinnaringin affects the expression of STAT3 protein25117567
C017096n-butoxyethanoln-butoxyethanol results in increased expression of STAT3 mRNA19812364
D009532NickelNickel results in increased expression of STAT3 mRNA24768652|2558310
C028007nickel monoxidenickel monoxide results in increased expression of STAT3 mRNA19167457
D009534NiclosamideMDV 3100 promotes the reaction [Niclosamide results in decreased phosphorylation of and results in decreased activity of STAT3 protein]25970160
D009534NiclosamideNiclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased phosphorylation of STAT3 protein]23894143
D009534Niclosamide[Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased phosphorylation of STAT3 protein]] which results in increased susceptibility to Erlotinib Hydrochloride23894143
D009534NiclosamideNiclosamide inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]25970160
D009534NiclosamideNiclosamide inhibits the reaction [STAT3 protein results in decreased susceptibility to MDV 3100]25970160
D009534NiclosamideNiclosamide inhibits the reaction [TNFSF11 protein results in increased phosphorylation of STAT3 protein]26792726
D009534NiclosamideNiclosamide results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of STAT3 protein25970160
D009534NiclosamideNiclosamide results in decreased expression of and results in decreased phosphorylation of STAT3 protein24552774
D009534NiclosamideNiclosamide results in decreased expression of STAT3 protein26116531
D009534NiclosamideNiclosamide results in decreased phosphorylation of STAT3 protein23333246|2389414
D009538Nicotine"[alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide co-treated with U 0126] inhibits the reaction [Nicotine promotes the reaction [RELA protein binds to STAT3 protein modified form]]"18448488
D009538Nicotine"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Nicotine promotes the reaction [RELA protein binds to STAT3 protein modified form]]"18448488
D009538NicotineHexamethonium inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488|2010694
D009538Nicotine[Lobeline binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]] inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488
D009538NicotineLobeline inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]20106947
D009538Nicotine[methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488
D009538Nicotine[Nicotine co-treated with Lipopolysaccharides] results in increased phosphorylation of STAT3 protein21606497
D009538NicotineNicotine inhibits the reaction [Cisplatin results in decreased activity of STAT3 protein]20106947
D009538NicotineNicotine inhibits the reaction [Paclitaxel results in decreased activity of STAT3 protein]20106947
D009538NicotineNicotine promotes the reaction [RELA protein binds to STAT3 protein modified form]18448488
D009538NicotineNicotine promotes the reaction [STAT3 protein binds to ZFP36 promoter]21606497
D009538NicotineNicotine results in increased activity of STAT3 protein18448488
D009538NicotineNicotine results in increased phosphorylation of and results in increased activity of STAT3 protein20106947
D009538NicotineNicotine results in increased phosphorylation of STAT3 protein18448488
D009538NicotinePropranolol inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488|2010694
D009538NicotineSTAT3 results in increased susceptibility to Nicotine20943775
D009538NicotineStaurosporine inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488
D009538NicotineU 0126 inhibits the reaction [Nicotine promotes the reaction [RELA protein binds to STAT3 protein modified form]]18448488
D009538NicotineU 0126 inhibits the reaction [Nicotine results in increased activity of STAT3 protein]18448488
D009538NicotineU 0126 inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488
D009538NicotineHMOX1 protein promotes the reaction [Nicotine results in increased phosphorylation of STAT3 protein]24095726
D009538NicotineNicotine results in increased phosphorylation of STAT3 protein24095726|2539642
D009538NicotineSTAT3 protein promotes the reaction [[Lipopolysaccharides co-treated with Nicotine] results in increased expression of HMOX1 mRNA]24095726
D009538NicotineSTAT3 protein promotes the reaction [[Lipopolysaccharides co-treated with Nicotine] results in increased expression of ZFP36 mRNA]24095726
D009538NicotineSTAT3 protein promotes the reaction [Nicotine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]24095726
D009538NicotineSTAT3 protein promotes the reaction [Nicotine results in increased expression of ZFP36 mRNA]24095726
D009538NicotineSTAT3 protein results in increased susceptibility to Nicotine24095726
D009538NicotineZFP36 protein promotes the reaction [Nicotine results in increased phosphorylation of STAT3 protein]24095726
D009538Nicotinezinc protoporphyrin inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]24095726
D009538NicotineNicotine affects the expression of STAT3 mRNA29155039
C013150nifuroxazidenifuroxazide inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]29291386
C007350nitrofennitrofen results in increased expression of STAT3 protein modified form25812446
D009582NitrofurantoinNitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]15748169
D009582NitrofurantoinRotenone promotes the reaction [Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]]15748169
D009582NitrofurantoinNitrofurantoin results in increased activity of STAT3 protein11841787
D009582NitrofurantoinNitrofurantoin results in increased expression of STAT3 mRNA11841787
D005996NitroglycerinNitroglycerin results in increased expression of STAT3 mRNA12102619
D009609Nitrous OxideNitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]15748169
D009609Nitrous OxideNitrous Oxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein]15748169
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STAT3 mRNA"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STAT3 mRNA]"18778698
C025256nonylphenolnonylphenol results in decreased phosphorylation of STAT3 protein15242752
C069741norcantharidinnorcantharidin results in decreased phosphorylation of STAT3 protein21266192
C404397NSC 680410Acetylcysteine inhibits the reaction [NSC 680410 results in decreased phosphorylation of STAT3 protein]16481037
C520337NSC 74859[NSC 74859 results in decreased activity of STAT3 protein] which results in increased activity of CASP3 protein24090995
C520337NSC 74859NSC 74859 results in decreased activity of STAT3 protein24090995|2561724
C516714NVP-TAE684EGF protein inhibits the reaction [NVP-TAE684 results in decreased phosphorylation of STAT3 protein]22843788
C516714NVP-TAE684NVP-TAE684 results in decreased phosphorylation of STAT3 protein22553343|2284378
C025589ochratoxin A[ochratoxin A results in increased susceptibility to Antigens] which results in increased expression of STAT3 mRNA28935500
C076029olanzapineolanzapine promotes the reaction [STAT3 protein binds to RGS7 promoter]18976543
C076029olanzapineolanzapine promotes the reaction [[STAT3 protein binds to RGS7 promoter] which results in increased expression of RGS7 mRNA]18976543
D009828Oleanolic AcidOleanolic Acid results in increased expression of STAT3 mRNA18706400
C507134ON 01910ON 01910 results in decreased phosphorylation of STAT3 protein25472472
D053683Oncostatin MOncostatin M promotes the reaction [STAT3 protein binds to SOCS3 promoter]24657799
D053683Oncostatin MSTAT3 protein affects the reaction [Oncostatin M promotes the reaction [BRD4 protein binds to SOCS3 promoter]]24657799
C105488ONO 1301"ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein]"28887131
C009618O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate"PON1 gene polymorphism affects the susceptibility to [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate affects the expression of STAT3 mRNA]"21673326
C009618O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate"O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased expression of STAT3 mRNA"21673326
C009618O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate"PON1 protein affects the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased expression of STAT3 mRNA]"21673326
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of STAT3 mRNA25729387
C029341oxophenylarsineHydrogen Peroxide promotes the reaction [oxophenylarsine affects the localization of STAT3 protein]10364193
C029341oxophenylarsineoxophenylarsine affects the localization of STAT3 protein10364193
C029341oxophenylarsineoxophenylarsine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT3 protein]11882386
C029341oxophenylarsineoxophenylarsine promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]10364193
C029341oxophenylarsineoxophenylarsine inhibits the reaction [EGF protein affects the localization of and results in increased activity of STAT3 protein]12093727
D010100OxygenApigenin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein]20153296
D010100Oxygenfisetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein]20153296
D010100Oxygengalangin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein]20153296
D010100OxygenOxygen deficiency results in increased phosphorylation of STAT3 protein20153296
D010100OxygenOxygen results in increased phosphorylation of STAT3 protein19587783
D010100OxygenQuercetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein]20153296
D010100Oxygencyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Oxygen results in increased phosphorylation of STAT3 protein]25203536
D010100OxygenIL6 protein inhibits the reaction [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] results in decreased phosphorylation of STAT3 protein]21940958
D010100Oxygen[[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein]21940958
D010100Oxygen[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] results in decreased phosphorylation of STAT3 protein21940958
D010100OxygenOxygen results in increased phosphorylation of STAT3 protein25203536
D010100Oxygen[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA23421680
D010100Oxygen[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 protein23421680
D010100Oxygenresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA]23421680
D010100Oxygenresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 protein]23421680
D010100OxygenSTAT3 protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased chemical synthesis of Reactive Oxygen Species]11524388
C021229oxyhyponitriteoxyhyponitrite inhibits the reaction [LIF protein results in increased activity of STAT3 protein]22905257
C021229oxyhyponitriteoxyhyponitrite inhibits the reaction [LIF protein results in increased activity of STAT3 protein]22905257
D010126OzoneOzone results in increased phosphorylation of STAT3 protein20826374
D017239PaclitaxelLuteolin promotes the reaction [Paclitaxel results in decreased phosphorylation of STAT3 protein]24525192
D017239PaclitaxelNicotine inhibits the reaction [Paclitaxel results in decreased activity of STAT3 protein]20106947
D017239PaclitaxelPaclitaxel promotes the reaction [Luteolin results in decreased phosphorylation of STAT3 protein]24525192
D017239PaclitaxelPaclitaxel results in decreased activity of STAT3 protein20106947
D017239PaclitaxelPaclitaxel results in decreased phosphorylation of STAT3 protein24525192
D017239PaclitaxelSTAT3 protein results in decreased susceptibility to Paclitaxel20106947
C496932panobinostatpanobinostat inhibits the reaction [STAT3 protein binds to GADD45G promoter]23681230
C496932panobinostatpanobinostat promotes the reaction [resveratrol inhibits the reaction [STAT3 protein binds to GADD45G promoter]]23681230
C496932panobinostatpanobinostat promotes the reaction [SRT2183 inhibits the reaction [STAT3 protein binds to GADD45G promoter]]23681230
C016030pantogabpantogab results in increased expression of STAT3 mRNA17379144
D010269Paraquat[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA23963992
D010269ParaquatMelatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA]23963992
D010269ParaquatParaquat results in increased expression of STAT3 mRNA alternative form17215068
D010269ParaquatSilymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA]23963992
D017374ParoxetineParoxetine results in decreased expression of STAT3 mRNA17499975
D017374ParoxetineParoxetine results in decreased expression of STAT3 protein17499975
D052638Particulate Matter"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]"17028263
D052638Particulate MatterButylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]17028263
D052638Particulate MatterParticulate Matter results in increased expression of STAT3 mRNA28412507
D052638Particulate MatterParticulate Matter results in increased phosphorylation of and affects the localization of STAT3 protein17028263
D052638Particulate Matter[STAT3 protein binds to CDKN1A promoter] promotes the reaction [Particulate Matter results in increased expression of CDKN1A mRNA]19329556
D052638Particulate MatterSTAT3 protein promotes the reaction [Particulate Matter results in increased expression of CDKN1A mRNA]19329556
C410127PCB 180"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased phosphorylation of STAT3 protein"24978599
C410127PCB 180"[2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased phosphorylation of STAT3 protein"24978599
C500599peroxyvanadateperoxyvanadate promotes the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]12847270
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein]16046413
C076715pervanadatepervanadate analog inhibits the reaction [Spiro Compounds analog results in decreased activity of STAT3 protein]25320076
C076715pervanadatepervanadate inhibits the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]17505005
C076715pervanadatepervanadate inhibits the reaction [Emodin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]23848338
D015232DinoprostoneDinoprostone inhibits the reaction [[Indomethacin results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein]21268125
D015232DinoprostoneDinoprostone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]]25432964
D010634PhenobarbitalPhenobarbital affects the expression of STAT3 mRNA23091169
D010656PhenylephrineCyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein]19299911
D010656PhenylephrinePhenylephrine affects the localization of STAT3 protein19299911
D010656PhenylephrinePhenylephrine results in increased expression of STAT319299911
D010656PhenylephrinePhenylephrine results in increased phosphorylation of and affects the localization of STAT3 protein27094369
D010656PhenylephrinePhenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein19299911
D010656PhenylephrinePRKCZ protein affects the reaction [Phenylephrine results in increased phosphorylation of and affects the localization of STAT3 protein]27094369
D010656PhenylephrineVerapamil inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein]19299911
D010665PhenylpropanolamineEnzyme Inhibitors inhibits the reaction [Phenylpropanolamine results in increased expression of STAT3 protein modified form]24792324
D010665PhenylpropanolaminePhenylpropanolamine results in increased activity of STAT3 protein24792324
D010665PhenylpropanolaminePhenylpropanolamine results in increased expression of STAT3 mRNA24792324
D010665PhenylpropanolaminePhenylpropanolamine results in increased expression of STAT3 protein modified form24792324
D010665PhenylpropanolamineS-ethyl glutathione inhibits the reaction [Phenylpropanolamine results in increased expression of STAT3 mRNA]24792324
D010665PhenylpropanolamineSTAT3 mRNA promotes the reaction [Phenylpropanolamine results in decreased expression of NPY mRNA]24792324
D010665PhenylpropanolamineSTAT3 mRNA promotes the reaction [Phenylpropanolamine results in increased expression of CAT mRNA]24792324
D010665PhenylpropanolamineSTAT3 mRNA promotes the reaction [Phenylpropanolamine results in increased expression of GSTA1 mRNA]24792324
D010665PhenylpropanolamineSTAT3 mRNA promotes the reaction [Phenylpropanolamine results in increased expression of POMC mRNA]24792324
D010665PhenylpropanolamineSTAT3 mRNA promotes the reaction [Phenylpropanolamine results in increased expression of SOD1 mRNA]24792324
D010665PhenylpropanolamineSTAT3 mRNA results in increased susceptibility to Phenylpropanolamine24792324
C018637phoronephorone results in increased activity of STAT3 protein11841787
C018637phoronephorone results in increased expression of STAT3 mRNA11841787
D010712Phosphatidic AcidsPhosphatidic Acids results in increased phosphorylation of and affects the localization of STAT3 protein16354768
D010798PhycocyaninPhycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]22986104
D010833Phytic AcidPhytic Acid inhibits the reaction [Urethane results in increased expression of and results in increased phosphorylation of STAT3 protein]22797328
D010833Phytic AcidPhytic Acid inhibits the reaction [Urethane results in increased expression of STAT3 mRNA]22797328
C008922piperinepiperine inhibits the reaction [IL2 protein results in increased phosphorylation of STAT3 protein]25655587
C006253pirinixic acidpirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein]27853831
C006253pirinixic acidpirinixic acid results in decreased expression of STAT3 mRNA17321000
C006253pirinixic acidpirinixic acid results in increased expression of STAT3 mRNA18445702
C006253pirinixic acidPPARA protein affects the reaction [pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased phosphorylation of STAT3 protein]]27853831
C006253pirinixic acidPPARA protein affects the reaction [pirinixic acid results in decreased expression of STAT3 mRNA]17321000
D010894Piroxicam[Piroxicam co-treated with Cisplatin] results in decreased expression of STAT3 mRNA21858171
D010936Plant ExtractsPlant Extracts analog results in increased phosphorylation of STAT3 protein25447409
D010936Plant ExtractsSTAT3 mutant form inhibits the reaction [Plant Extracts analog results in increased expression of HOTAIR mRNA]25447409
D011070Poly I-CPoly I-C results in increased activity of and results in increased localization of STAT3 protein17345100
D011070Poly I-CIL6 protein affects the reaction [Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein]21195166
D011070Poly I-CPoly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein21195166
D011192Potassium DichromateLCK protein affects the reaction [Potassium Dichromate results in increased phosphorylation of STAT3 protein alternative form]17078813
D011192Potassium DichromatePotassium Dichromate results in increased phosphorylation of and results in increased activity of and affects the localization of STAT3 protein alternative form17078813
C058808praeruptorin Cpraeruptorin C inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]22083490
C036455praeruptorin Epraeruptorin E inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]22083490
D017035PravastatinPravastatin results in decreased phosphorylation of STAT3 protein19330073
D011374ProgesteroneProgesterone inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]21768398
C045950propiconazolepropiconazole results in decreased expression of STAT3 mRNA21278054
D015742PropofolHMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]24810525
D015742PropofolPropofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]24810525
D015742PropofolPropofol promotes the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]24810525
D015742PropofolPropofol results in increased phosphorylation of STAT3 protein24810525
D015742PropofolSTAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]24810525
D015742PropofolSTAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]]24810525
D015742PropofolSTAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]24810525
D015742Propofolzinc protoporphyrin inhibits the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]24810525
D011433PropranololPropranolol inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488|2010694
C456319PS1145PS1145 inhibits the reaction [LEP protein results in increased phosphorylation of STAT3 protein]27226618
C107773pterostilbenepterostilbene results in decreased activity of STAT3 protein23313376
C107773pterostilbenepterostilbene results in decreased expression of STAT3 protein modified form22450950
C107773pterostilbenepterostilbene results in decreased phosphorylation of STAT3 protein26138072
C107773pterostilbenepterostilbene results in decreased phosphorylation of STAT3 protein26138072
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein]22696236
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [bisphenol A results in increased phosphorylation of STAT3 protein]24349194
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]19429262
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [arsenic trioxide results in increased phosphorylation of and affects the localization of STAT3 protein]27174766
C020972pyrrolidine dithiocarbamic acid"pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of STAT3 mRNA]"11578593
D011794QuercetinQuercetin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]16150460
D011794QuercetinDDIT3 protein affects the reaction [Quercetin results in decreased phosphorylation of STAT3 protein]25611565
D011794Quercetin[docetaxel co-treated with epigallocatechin gallate co-treated with Quercetin] results in decreased expression of and results in decreased phosphorylation of STAT3 protein25655047
D011794Quercetindocetaxel promotes the reaction [[epigallocatechin gallate co-treated with Quercetin] results in decreased phosphorylation of STAT3 protein]25655047
D011794Quercetin[epigallocatechin gallate co-treated with Quercetin] promotes the reaction [docetaxel results in decreased phosphorylation of STAT3 protein]25655047
D011794Quercetin[epigallocatechin gallate co-treated with Quercetin] results in decreased expression of and results in decreased phosphorylation of STAT3 protein25655047
D011794QuercetinQuercetin inhibits the reaction [IL6 protein promotes the reaction [STAT3 protein binds to CCND1 promoter]]22394507
D011794QuercetinQuercetin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]22394507|2583005
D011794QuercetinQuercetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of STAT3 protein]20153296
D011794QuercetinQuercetin promotes the reaction [arctigenin results in decreased phosphorylation of STAT3 protein]25380086
D011794QuercetinQuercetin results in decreased activity of and results in decreased phosphorylation of STAT3 protein27175602
D011794QuercetinQuercetin results in decreased phosphorylation of and affects the localization of STAT3 protein24275163
D011794QuercetinQuercetin results in decreased phosphorylation of STAT3 protein24275163|2561156
D011794QuercetinQuercetin results in increased phosphorylation of STAT3 protein22230496
D011794Quercetin[Quercetin results in increased susceptibility to Cisplatin] which results in decreased phosphorylation of STAT3 protein25611565
D011794Quercetinsalubrinal inhibits the reaction [Quercetin results in decreased phosphorylation of STAT3 protein]25611565
D011794Quercetintauroursodeoxycholic acid inhibits the reaction [Quercetin results in decreased phosphorylation of STAT3 protein]25611565
D011794QuercetinQuercetin results in decreased expression of STAT3 mRNA24275163
D011794QuercetinQuercetin results in decreased phosphorylation of STAT3 protein24275163
D011794QuercetinQuercetin inhibits the reaction [Fructose results in decreased phosphorylation of STAT3 protein]23533474
D011794QuercetinQuercetin inhibits the reaction [Fructose results in increased phosphorylation of STAT3 protein]22426011
D020849Raloxifene Hydrochloride"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]]"17336289
D020849Raloxifene Hydrochloride"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased phosphorylation of STAT3 protein]]"17336289
D020849Raloxifene Hydrochloride[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]17336289
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride inhibits the reaction [Estradiol results in increased phosphorylation of STAT3 protein]17336289
D017382Reactive Oxygen Species[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]] which results in increased phosphorylation of STAT3 protein23376140
D017382Reactive Oxygen Species[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]] which results in increased phosphorylation of STAT3 protein] which results in increased expression of MT223376140
D017382Reactive Oxygen Species[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein23376140
D017382Reactive Oxygen Species[[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein] promotes the reaction [STAT3 protein binds to STAT3 protein]23376140
D017382Reactive Oxygen SpeciesSTAT3 protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased chemical synthesis of Reactive Oxygen Species]11524388
D017382Reactive Oxygen SpeciesSTAT3 protein results in decreased chemical synthesis of Reactive Oxygen Species11524388
C402365resiquimodresiquimod results in increased expression of STAT3 mRNA17238832
C059514resveratrolresveratrol inhibits the reaction [IL1B protein results in increased activity of STAT3 protein]19011540
C059514resveratrolresveratrol inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]16150460
C059514resveratrolresveratrol results in decreased expression of STAT3 mRNA24305840
C059514resveratrolresveratrol results in increased expression of STAT3 mRNA24305840
C059514resveratrol"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of STAT3 protein modified form]]"24064760
C059514resveratrolNDUFA13 protein affects the reaction [resveratrol results in decreased phosphorylation of STAT3 protein]25351437
C059514resveratrolpanobinostat promotes the reaction [resveratrol inhibits the reaction [STAT3 protein binds to GADD45G promoter]]23681230
C059514resveratrolPTPRE protein affects the reaction [resveratrol results in decreased phosphorylation of STAT3 protein]26911335
C059514resveratrolresveratrol affects the activity of STAT3 protein25063218
C059514resveratrolresveratrol affects the localization of STAT3 protein18592012|2691133
C059514resveratrol[resveratrol co-treated with Bortezomib] results in decreased phosphorylation of STAT3 protein17164350
C059514resveratrol[resveratrol co-treated with Thalidomide] results in decreased phosphorylation of STAT3 protein17164350
C059514resveratrolresveratrol inhibits the reaction [Glucose results in increased expression of STAT3 protein modified form]24064760
C059514resveratrolresveratrol inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]17164350
C059514resveratrolresveratrol inhibits the reaction [STAT3 protein binds to GADD45G promoter]23681230
C059514resveratrolresveratrol inhibits the reaction [STAT3 protein results in increased expression of BCL2L1 protein]16546976
C059514resveratrolresveratrol inhibits the reaction [STAT3 protein results in increased expression of CCND1 protein]16546976
C059514resveratrolresveratrol inhibits the reaction [STAT3 protein results in increased expression of MCL1 protein]16546976
C059514resveratrolresveratrol promotes the reaction [sorafenib results in decreased phosphorylation of STAT3 protein]26911335
C059514resveratrolresveratrol results in decreased acetylation of STAT3 protein23681230
C059514resveratrolresveratrol results in decreased activity of and results in decreased phosphorylation of STAT3 protein26911335|2706401
C059514resveratrolresveratrol results in decreased activity of STAT3 protein21503893|2506149
C059514resveratrolresveratrol results in decreased expression of and affects the localization of STAT3 protein modified form25896424
C059514resveratrolresveratrol results in decreased expression of STAT323372833
C059514resveratrolresveratrol results in decreased expression of STAT3 mRNA18592012|2458704
C059514resveratrolresveratrol results in decreased expression of STAT3 protein18592012|2368123
C059514resveratrolresveratrol results in decreased expression of STAT3 protein modified form23681230|2406476
C059514resveratrolresveratrol results in decreased phosphorylation of and affects the localization of STAT3 protein17164350
C059514resveratrolresveratrol results in decreased phosphorylation of and results in decreased activity of STAT3 protein16546976|1822242
C059514resveratrolresveratrol results in decreased phosphorylation of and results in decreased expression of STAT3 protein24587049
C059514resveratrolresveratrol results in decreased phosphorylation of STAT3 protein18592012|2409099
C059514resveratrolresveratrol results in increased phosphorylation of STAT3 protein22748497
C059514resveratrolSIRT1 protein affects the reaction [resveratrol results in decreased expression of STAT3 protein modified form]24064760
C059514resveratrolSOCS1 protein affects the reaction [resveratrol results in decreased phosphorylation of STAT3 protein]27064016
C059514resveratrolVanadates affects the reaction [resveratrol results in decreased phosphorylation of STAT3 protein]27064016
C059514resveratrolVanadates inhibits the reaction [resveratrol results in decreased phosphorylation of STAT3 protein]26911335
C059514resveratrolresveratrol results in decreased expression of STAT3 protein modified form19063842
C059514resveratrolIL10 protein affects the reaction [resveratrol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]]25576658
C059514resveratrolresveratrol inhibits the reaction [APP protein results in increased phosphorylation of STAT3 protein]22118570
C059514resveratrolresveratrol inhibits the reaction [Dextran Sulfate results in increased expression of STAT3 protein]26074695
C059514resveratrolresveratrol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of and results in increased activity of STAT3 protein]20155626
C059514resveratrol"resveratrol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of STAT3 protein]"25651848
C059514resveratrolresveratrol inhibits the reaction [[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of STAT3 protein]22118570
C059514resveratrolresveratrol inhibits the reaction [Lipopolysaccharides results in increased activity of STAT3 protein]22118570
C059514resveratrolresveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]26100520
C059514resveratrolresveratrol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]25576658
C059514resveratrolresveratrol promotes the reaction [ursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]]26100520
C059514resveratrolresveratrol results in decreased activity of and results in decreased phosphorylation of STAT3 protein19796711
C059514resveratrolresveratrol results in decreased expression of STAT3 protein modified form19063842
C059514resveratrolresveratrol results in decreased phosphorylation of STAT3 protein26138072
C059514resveratrolresveratrol results in increased expression of STAT3 protein25505154
C059514resveratrolresveratrol results in increased phosphorylation of STAT3 protein21342247
C059514resveratrolSTAT3 protein results in increased susceptibility to resveratrol21342247
C059514resveratrolursolic acid promotes the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]]26100520
C059514resveratrolresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 mRNA]23421680
C059514resveratrolresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of STAT3 protein]23421680
C059514resveratrolresveratrol results in decreased expression of STAT3 mRNA23419489
C059514resveratrolresveratrol inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]23782265
C059514resveratrolresveratrol promotes the reaction [Colforsin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]]23782265
C059514resveratrolresveratrol results in decreased activity of STAT3 protein18454317|2116167
C089032rimonabantrimonabant inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein]16046413
D018967RisperidoneRisperidone inhibits the reaction [Rotenone results in decreased expression of STAT3 mRNA]17442543
D012312RitodrineRitodrine results in increased phosphorylation of STAT3 protein23370008
D019438RitonavirRitonavir results in decreased phosphorylation of STAT3 protein21270666
C116926rofecoxibrofecoxib results in increased expression of STAT3 mRNA17070997
D020889RolipramRolipram promotes the reaction [Colforsin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]]23782265
C089730rosiglitazonerosiglitazone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT3 protein]12584205
C089730rosiglitazonerosiglitazone inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]21599458
C089730rosiglitazonerosiglitazone inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein]12584205
C089730rosiglitazonerosiglitazone results in decreased phosphorylation of STAT3 protein17394460
D012402RotenoneRotenone inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]15748169
D012402RotenoneRotenone inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]19635391
D012402RotenoneRotenone promotes the reaction [Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]]15748169
D012402RotenoneThioctic Acid inhibits the reaction [Rotenone inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]19635391
D012402RotenoneSTAT3 protein affects the susceptibility to Rotenone20224768
D012402RotenoneRisperidone inhibits the reaction [Rotenone results in decreased expression of STAT3 mRNA]17442543
D012402RotenoneRotenone results in decreased expression of STAT3 mRNA17442543
D012431RutinRutin inhibits the reaction [Carbon Tetrachloride results in increased expression of STAT3 mRNA]26062544
D012431RutinRutin inhibits the reaction [Fructose results in increased phosphorylation of STAT3 protein]22426011
C513635S-2-pentyl-4-pentynoic hydroxamic acidS-2-pentyl-4-pentynoic hydroxamic acid results in increased expression of STAT3 mRNA21427059
C025759saikosaponinsaikosaponin inhibits the reaction [Acetaminophen results in increased phosphorylation of STAT3 protein]25265579
C496827salubrinalsalubrinal inhibits the reaction [Quercetin results in decreased phosphorylation of STAT3 protein]25611565
C410958sauchinonesauchinone inhibits the reaction [IFNG protein results in increased phosphorylation of STAT3 protein]21167929
C410958sauchinonesauchinone inhibits the reaction [IL1B protein results in increased phosphorylation of STAT3 protein]21167929
C093642SB 203580SB 203580 inhibits the reaction [Cadmium results in increased phosphorylation of STAT3 protein]21783819
C115461SC 560SC 560 inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]25432964
D064586Selenic AcidSelenic Acid results in increased activity of STAT3 protein22366233
D064586Selenic AcidSelenic Acid promotes the reaction [LIF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]22366233
C002979selenomethylselenocysteineselenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]25321483
C002979selenomethylselenocysteineSTAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]25321483
D020280SertralineSertraline results in decreased expression of STAT3 mRNA17499975
D020280SertralineSertraline results in decreased expression of STAT3 protein17499975
C042431S-ethyl glutathioneS-ethyl glutathione inhibits the reaction [Phenylpropanolamine results in increased expression of STAT3 mRNA]24792324
D012822Silicon Dioxide[Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA22155353
D012822Silicon DioxideIL6RA mRNA affects the reaction [Silicon Dioxide results in increased expression of STAT3 mRNA]20490462
D012822Silicon DioxideSilicon Dioxide results in increased expression of STAT3 mRNA20490462|2322117
D012838SilymarinSilymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA]23963992
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in decreased phosphorylation of STAT3 protein]18453621
D019821SimvastatinSimvastatin results in decreased activity of STAT3 protein19886038
D019821SimvastatinSimvastatin results in decreased phosphorylation of STAT3 protein18453621|2191000
D019821SimvastatinSimvastatin affects the expression of STAT3 protein17507688
D019821SimvastatinSimvastatin results in decreased activity of STAT3 protein19886038
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]]16534557
D019821SimvastatinSimvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]16534557
D019821SimvastatinSimvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein modified form]19100119
D019821SimvastatinSimvastatin inhibits the reaction [CTF1 results in increased phosphorylation of STAT3 protein]18400235
D019821SimvastatinSimvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]20821229
D019821SimvastatinSimvastatin results in decreased phosphorylation of STAT3 protein18400235
D020123SirolimusSirolimus inhibits the reaction [IFNG protein results in decreased phosphorylation of STAT3 protein]16427044
D020123SirolimusSirolimus results in decreased phosphorylation of STAT3 protein20038814
D020123SirolimusSirolimus inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of STAT3 protein]26648565
D020123SirolimusSirolimus results in decreased phosphorylation of STAT3 protein16391472
D012906SmokeSmoke analog results in increased phosphorylation of STAT3 protein25447409
D012906SmokeSTAT3 mutant form inhibits the reaction [Smoke analog results in increased expression of HOTAIR mRNA]25447409
C110881S-nitro-N-acetylpenicillamineS-nitro-N-acetylpenicillamine inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]16150460
C017947sodium arsenite[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of STAT3 mRNA23192986
C017947sodium arsenitesodium arsenite inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]15116095
C017947sodium arsenitesodium arsenite inhibits the reaction [JAK1 protein results in increased phosphorylation of STAT3 protein]15116095
C017947sodium arsenitesodium arsenite results in decreased expression of STAT317224793
C017947sodium arsenitesodium arsenite results in increased expression of and results in increased phosphorylation of STAT3 protein28444938
C017947sodium arsenitesodium arsenite results in increased expression of STAT3 mRNA28444938
C017947sodium arseniteSTAT3 protein promotes the reaction [sodium arsenite results in increased expression of BCL2 protein]28444938
C017947sodium arseniteSTAT3 protein promotes the reaction [sodium arsenite results in increased expression of CCND1 mRNA]28444938
C017947sodium arseniteSTAT3 protein promotes the reaction [sodium arsenite results in increased expression of CCND1 protein]28444938
C017947sodium arseniteSTAT3 protein promotes the reaction [sodium arsenite results in increased expression of PCNA mRNA]28444938
C017947sodium arseniteSTAT3 protein promotes the reaction [sodium arsenite results in increased expression of PCNA protein]28444938
C017947sodium arseniteSTAT3 protein promotes the reaction [sodium arsenite results in increased expression of PTGS2 mRNA]28444938
C017947sodium arseniteSTAT3 protein promotes the reaction [sodium arsenite results in increased expression of PTGS2 protein]28444938
C017947sodium arsenite2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]20008137
C017947sodium arsenite"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]"20008137
C017947sodium arseniteEstrogens inhibits the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]26631322
C017947sodium arseniteIL6 protein affects the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]20008137
C017947sodium arsenite[IL6 protein results in increased activity of STAT3 protein] which results in decreased susceptibility to sodium arsenite23143138
C017947sodium arseniteSOCS3 mutant form inhibits the reaction [Estrogens inhibits the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]]26631322
C017947sodium arsenitesodium arsenite results in decreased expression of STAT3 protein modified form23143138
C017947sodium arsenitesodium arsenite results in increased phosphorylation of STAT3 protein20008137|2663132
C017947sodium arseniteSTAT3 protein results in decreased susceptibility to sodium arsenite23143138
C016104sodium bichromatesodium bichromate results in increased expression of STAT3 mRNA25993096
D0150862,6-Dichloroindophenol"2,6-Dichloroindophenol inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]"19635391
D012999SomanSoman results in increased expression of STAT3 mRNA19281266
C471405sorafenibresveratrol promotes the reaction [sorafenib results in decreased phosphorylation of STAT3 protein]26911335
C471405sorafenibsorafenib analog results in decreased phosphorylation of STAT3 protein21531053
C471405sorafenibsorafenib inhibits the reaction [Acids results in increased phosphorylation of STAT3 protein]18512153
C471405sorafenibsorafenib inhibits the reaction [SRC protein results in increased phosphorylation of STAT3 protein]20881478
C471405sorafenibsorafenib inhibits the reaction [Taurocholic Acid results in increased phosphorylation of STAT3 protein]18512153
C471405sorafenibsorafenib inhibits the reaction [TGFB1 protein results in increased phosphorylation of STAT3 protein]21360571
C471405sorafenibsorafenib results in decreased phosphorylation of and results in decreased activity of STAT3 protein20881478
C471405sorafenibsorafenib results in decreased phosphorylation of STAT3 protein19001435|2691133
C471405sorafenibsorafenib affects the localization of STAT3 protein21360571
C471405sorafenibsorafenib results in decreased phosphorylation of STAT3 protein21750559
C471405sorafenib[sorafenib results in decreased phosphorylation of STAT3 protein] which results in increased susceptibility to TNFSF10 protein21750559
D013141Spiro Compoundspervanadate analog inhibits the reaction [Spiro Compounds analog results in decreased activity of STAT3 protein]25320076
D013141Spiro CompoundsSpiro Compounds analog results in decreased activity of STAT3 protein25320076
D013141Spiro CompoundsSpiro Compounds analog results in decreased phosphorylation of and affects the localization of STAT3 protein25320076
C526005SR140333BSR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of STAT3 protein]16788306
C525423SRT2183panobinostat promotes the reaction [SRT2183 inhibits the reaction [STAT3 protein binds to GADD45G promoter]]23681230
C525423SRT2183SRT2183 inhibits the reaction [STAT3 protein modified form binds to GADD45G promoter]23681230
C525423SRT2183SRT2183 results in decreased acetylation of STAT3 protein23681230
C525423SRT2183SRT2183 results in decreased expression of STAT3 protein23681230
C525423SRT2183SRT2183 results in decreased expression of STAT3 protein modified form23681230
C517409statticstattic affects the reaction [Arsenicals affects the phosphorylation of STAT3 protein]23255093
C517409statticstattic affects the reaction [IL6 protein affects the phosphorylation of STAT3 protein]25740948
C517409statticstattic inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]24627483
C517409statticstattic results in decreased phosphorylation of STAT3 protein24627483
C517409statticstattic inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]28739487
C517409statticstattic inhibits the reaction [deoxynivalenol results in increased expression of STAT3 mRNA]22454431
C517409statticstattic inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT3 protein]22454431
C517409statticstattic inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]22454431
C517409statticstattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]22454431
C517409statticstattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]25740948
C517409statticstattic inhibits the reaction [zoniporide results in increased phosphorylation of STAT3 protein]20942815
C517409statticstattic results in decreased activity of STAT3 protein19153190|2094281
D019311StaurosporineStaurosporine inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488
D013267StilbenesStilbenes analog affects the activity of STAT3 protein25063218
D013311StreptozocinAcetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]21912612
D013311StreptozocinAllopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]]21912612
D013311StreptozocinEnalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA]19958114
D013311StreptozocinEnalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 protein]19958114
D013311Streptozocinnifuroxazide inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]29291386
D013311StreptozocinPropofol promotes the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]24810525
D013311Streptozocinrosiglitazone inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]21599458
D013311StreptozocinSimvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]20821229
D013311StreptozocinStreptozocin results in decreased phosphorylation of STAT3 protein21912612|2481052
D013311StreptozocinStreptozocin results in increased expression of STAT3 mRNA19958114
D013311StreptozocinStreptozocin results in increased expression of STAT3 protein19958114
D013311StreptozocinStreptozocin results in increased phosphorylation of STAT3 protein20821229|2159945
C105686SU 5402SU 5402 results in decreased expression of STAT3 protein14871245
C416927SU 6656[[tyrphostin AG 1478 results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]23376140
D013467SulindacBIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein]17401459
D013467SulindacBIRC5 protein inhibits the reaction [Sulindac results in decreased expression of STAT3 protein modified form]17401459
D013467SulindacSulindac results in decreased expression of STAT3 protein17401459
D013467SulindacSulindac results in decreased expression of STAT3 protein modified form17401459
D013467SulindacSulindac results in decreased phosphorylation of STAT3 protein11861373
C025462sulindac sulfidesulindac sulfide results in decreased expression of and results in decreased phosphorylation of STAT3 protein17566705
C025462sulindac sulfidesulindac sulfide results in decreased expression of STAT3 mRNA17566705
C458508T 0070907"T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]"19922793
C458508T 0070907"T 0070907 inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]"19922793
C458508T 0070907T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased expression of STAT3 protein]]19922793
C458508T 0070907T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [LIF protein results in increased phosphorylation of STAT3 protein]]19922793
D013605T-2 Toxin"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]"22454431
D013605T-2 Toxin"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]"22454431
D013605T-2 Toxinstattic inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]22454431
D013605T-2 Toxinstattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]22454431
D013605T-2 ToxinT-2 Toxin results in increased expression of STAT3 mRNA22454431
D013605T-2 ToxinT-2 Toxin results in increased phosphorylation of STAT3 protein22454431
D013605T-2 ToxinT-2 Toxin results in decreased expression of STAT3 mRNA26141394
D016559TacrolimusTacrolimus results in increased phosphorylation of STAT3 protein23958496
D013629TamoxifenTamoxifen inhibits the reaction [[bisphenol A affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
D013629TamoxifenTamoxifen inhibits the reaction [[Endosulfan affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
D013629TamoxifenTamoxifen inhibits the reaction [[Methoxychlor affects the activity of ESR1 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]]14975756
D013629TamoxifenTamoxifen inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased activity of STAT3 protein]16860915
D013629TamoxifenTamoxifen results in increased expression of STAT3 protein modified form17901229
D013654TaurineTaurine results in decreased expression of STAT3 mRNA16579726
D013656Taurocholic Acidsorafenib inhibits the reaction [Taurocholic Acid results in increased phosphorylation of STAT3 protein]18512153
D013656Taurocholic AcidTaurocholic Acid results in increased phosphorylation of STAT3 protein18512153
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid inhibits the reaction [Quercetin results in decreased phosphorylation of STAT3 protein]25611565
C045037testosterone-3-carboxymethyloxime-bovine serum albumin conjugatetestosterone-3-carboxymethyloxime-bovine serum albumin conjugate results in increased activity of STAT320189893
D013749Tetrachlorodibenzodioxin[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of STAT3 protein]23639249
D013749TetrachlorodibenzodioxinSRC protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of STAT3 mRNA]14708085
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of STAT3 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of STAT3 mRNA14708085|2405805
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of STAT3 protein23639249
D013752TetracyclineTetracycline results in increased expression of STAT3 mRNA17522070
D013755Tetradecanoylphorbol Acetatediphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]20523355
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in decreased phosphorylation of STAT3 protein25128825
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein20523355|2449623
D013755Tetradecanoylphorbol Acetatebisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]]24496235
D013755Tetradecanoylphorbol Acetatebisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein]24496235
D013755Tetradecanoylphorbol Acetatecorosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]26513295
D013755Tetradecanoylphorbol Acetatecorosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]26513295
D013755Tetradecanoylphorbol Acetatemaslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]26513295
D013755Tetradecanoylphorbol Acetatemaslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]26513295
D013755Tetradecanoylphorbol AcetatePhycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]22986104
D013755Tetradecanoylphorbol Acetateresveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]26100520
D013755Tetradecanoylphorbol Acetateresveratrol promotes the reaction [ursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]]26100520
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]24496235
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of STAT326100520
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein24496235
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein22986104|2651329
D013755Tetradecanoylphorbol Acetateursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]26100520
D013755Tetradecanoylphorbol Acetateursolic acid promotes the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]]26100520
D013792Thalidomide[resveratrol co-treated with Thalidomide] results in decreased phosphorylation of STAT3 protein17164350
D013792ThalidomideThalidomide analog results in decreased phosphorylation of STAT3 protein15858615
D013792ThalidomideThalidomide promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]17505005
D019284ThapsigarginThapsigargin results in increased expression of STAT3 protein24648495
D019284ThapsigarginThapsigargin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]19285962
D013806TheophyllineTheophylline results in increased expression of STAT3 mRNA16083514
D008063Thioctic AcidThioctic Acid inhibits the reaction [Cadmium Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]19635391
D008063Thioctic AcidThioctic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]19635391
D008063Thioctic AcidThioctic Acid inhibits the reaction [Rotenone inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]19635391
D008063Thioctic AcidThioctic Acid inhibits the reaction [Zinc deficiency affects the localization of STAT3 protein]28086195
D013882Thiosemicarbazones[Thiosemicarbazones binds to Copper] which results in increased expression of STAT3 protein20931265
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of STAT3 mRNA28065790
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of STAT3 mRNA28111298
C479163tofacitinibtofacitinib inhibits the reaction [IL21 protein results in increased phosphorylation of STAT3 protein]21383241
C479163tofacitinibtofacitinib inhibits the reaction [[IL6 protein co-treated with IL6R protein] results in increased phosphorylation of STAT3 protein]21548952
C479163tofacitinibtofacitinib inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]21383241|2184413
C479163tofacitinibtofacitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of STAT3 protein]23968543
C479163tofacitinibtofacitinib inhibits the reaction [OSM protein results in increased phosphorylation of STAT3 protein]21548952|2525291
C479163tofacitinibtofacitinib results in decreased activity of STAT3 protein22348037
C479163tofacitinibtofacitinib results in decreased expression of STAT3 protein modified form25398374|2705972
C479163tofacitinibtofacitinib results in decreased phosphorylation of STAT3 protein25487280|2624487
C479163tofacitinibtofacitinib inhibits the reaction [IL1B protein results in increased phosphorylation of STAT3 protein]21937456
C479163tofacitinibtofacitinib inhibits the reaction [IL21 protein results in increased phosphorylation of STAT3 protein]21383241
C479163tofacitinibtofacitinib inhibits the reaction [IL23A protein results in increased phosphorylation of STAT3 protein]21937456
C479163tofacitinibtofacitinib inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]21383241|2428583
C066340tolcaponetolcapone results in increased expression of STAT3 mRNA24136188
D014050TolueneToluene results in increased expression of STAT3 mRNA21601613
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of STAT3 mRNA25729387
C483909torcetrapibtorcetrapib results in increased phosphorylation of STAT3 protein25617244
D014108Tosylphenylalanyl Chloromethyl KetoneTosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]10616907
D014118Toxins, Biological"Toxins, Biological affects the expression of STAT3 mRNA"19682533
D014212TretinoinTretinoin results in increased expression of STAT3 mRNA18230668
D014212TretinoinTretinoin affects the localization of STAT3 protein17026715
D014212TretinoinU 0126 inhibits the reaction [Tretinoin affects the localization of STAT3 protein]17026715
C529200trichloronitritodiammineplatinum(IV)trichloronitritodiammineplatinum(IV) results in decreased activity of STAT3 protein19456249
C046488trimethyltintrimethyltin results in increased expression of STAT3 mRNA21435392
C046488trimethyltintrimethyltin results in increased expression of STAT3 protein21435392
D014302Trinitrobenzenesulfonic Acidstattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]25740948
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein25740948
C000608764triphenyl(phenylethynyl)phosphoniumtriphenyl(phenylethynyl)phosphonium results in decreased expression of STAT3 protein26984758
C001899triptolidetriptolide results in increased expression of STAT3 mRNA24949944
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of STAT3 mRNA"26179874
C080163trovafloxacin"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of STAT3 mRNA"18930950
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [bisphenol A results in increased expression of STAT3 mRNA]21909620
C101044tyrphostin AG 1478[[tyrphostin AG 1478 results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein]23376140
C101044tyrphostin AG 1478[tyrphostin AG 1478 results in decreased activity of EGFR protein] which results in decreased phosphorylation of STAT3 protein21268125
C113580U 0126"[alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide co-treated with U 0126] inhibits the reaction [Nicotine promotes the reaction [RELA protein binds to STAT3 protein modified form]]"18448488
C113580U 0126U 0126 inhibits the reaction [Nicotine promotes the reaction [RELA protein binds to STAT3 protein modified form]]18448488
C113580U 0126U 0126 inhibits the reaction [Nicotine results in increased activity of STAT3 protein]18448488
C113580U 0126U 0126 inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]18448488
C113580U 0126U 0126 inhibits the reaction [Tretinoin affects the localization of STAT3 protein]17026715
D014520UrethaneUrethane results in increased expression of STAT3 mRNA28818685
D014520UrethanePhytic Acid inhibits the reaction [Urethane results in increased expression of and results in increased phosphorylation of STAT3 protein]22797328
D014520UrethanePhytic Acid inhibits the reaction [Urethane results in increased expression of STAT3 mRNA]22797328
D014520UrethaneUrethane results in decreased expression of STAT3 mRNA12400877
D014520UrethaneUrethane results in increased expression of and results in increased phosphorylation of STAT3 protein22797328
D014520UrethaneUrethane results in increased expression of STAT3 mRNA22797328
C005466ursolic acidresveratrol promotes the reaction [ursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]]26100520
C005466ursolic acidursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]26100520
C005466ursolic acidursolic acid promotes the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]]26100520
C406224valdecoxibvaldecoxib results in increased expression of STAT3 mRNA24136188
D014635Valproic AcidValproic Acid affects the expression of STAT3 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of STAT3 mRNA19101580|2317975
D014635Valproic AcidValproic Acid results in increased expression of STAT3 mRNA21427059
D000068756ValsartanValsartan inhibits the reaction [AGT protein affects the localization of STAT3 protein]12846741
D000068756ValsartanValsartan inhibits the reaction [AGT protein results in increased activity of STAT3 protein]12846741
D000068756ValsartanValsartan inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]12846741
D014638VanadatesButylated Hydroxyanisole inhibits the reaction [Vanadates results in increased phosphorylation of STAT3 protein]17028263
D014638VanadatesVanadates affects the reaction [resveratrol results in decreased phosphorylation of STAT3 protein]27064016
D014638VanadatesVanadates inhibits the reaction [resveratrol results in decreased phosphorylation of STAT3 protein]26911335
D014638VanadatesVanadates promotes the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]10364193
D014638VanadatesVanadates results in decreased expression of STAT3 mRNA22714537
D014638VanadatesVanadates results in increased phosphorylation of STAT3 protein17028263
D014638VanadatesVanadates promotes the reaction [LIF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]22366233
D014639VanadiumVanadium promotes the reaction [LEP protein results in increased phosphorylation of STAT3 protein]16195403
C034028vanadyl sulfatevanadyl sulfate results in increased expression of STAT3 mRNA16330358
D014640VancomycinVancomycin results in decreased expression of STAT3 mRNA18930951
D001335Vehicle Emissions"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Vehicle Emissions results in increased phosphorylation of STAT3 protein]"17028263
D001335Vehicle EmissionsButylated Hydroxyanisole inhibits the reaction [Vehicle Emissions results in increased phosphorylation of STAT3 protein]17028263
D001335Vehicle Emissions[STAT3 protein binds to CDKN1A promoter] promotes the reaction [Vehicle Emissions results in increased expression of CDKN1A mRNA]19329556
D001335Vehicle EmissionsSTAT3 protein promotes the reaction [Vehicle Emissions results in increased expression of CDKN1A mRNA]19329556
D001335Vehicle EmissionsVehicle Emissions results in increased phosphorylation of and affects the localization of STAT3 protein17028263
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of STAT3 gene25560391
D014700VerapamilVerapamil inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]19299911
D014700VerapamilVerapamil inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased expression of STAT3 protein]19299911
D014747VinblastineVinblastine deficiency results in decreased activity of and affects the localization of STAT3 protein28086195
D014800VitalliumVitallium analog results in increased expression of STAT3 mRNA23825117
D014801Vitamin AVitamin A affects the expression of STAT3 protein15963505
C111237vorinostatvorinostat inhibits the reaction [STAT3 protein binds to BMF promoter]25321483
C528002Weichang'anWeichang'an results in decreased expression of STAT3 mRNA17498489|1816129
C528002Weichang'anWeichang'an results in decreased phosphorylation of STAT3 protein18161298|1820525
C009684withaferin Awithaferin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of STAT3 protein]21396905
C519885WP1066"WP1066 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]"28284859
C519885WP1066WP1066 inhibits the reaction [DDT results in increased phosphorylation of STAT3 protein]24820114
C519885WP1066WP1066 inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]24627483
C519885WP1066WP1066 results in decreased phosphorylation of STAT3 protein18056455|1824554
C519885WP1066[WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin B24316209
C519885WP1066[WP1066 results in decreased activity of STAT3 protein] which results in decreased susceptibility to cucurbitacin I24316209
C519885WP1066WP1066 results in decreased activity of STAT3 protein24316209
C501648WP9QY peptideWP9QY peptide inhibits the reaction [LEP protein results in increased phosphorylation of STAT3 protein]27226618
D015032ZincThioctic Acid inhibits the reaction [Zinc deficiency affects the localization of STAT3 protein]28086195
D015032ZincZinc deficiency results in decreased activity of STAT3 protein28086195
D015032ZincZinc deficiency results in decreased phosphorylation of STAT3 protein28086195
D015032ZincZinc deficiency results in decreased activity of STAT3 protein28086195
D015032ZincZinc deficiency results in decreased phosphorylation of and affects the localization of STAT3 protein28086195
C017803zinc protoporphyrinzinc protoporphyrin inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]24095726
C017803zinc protoporphyrinzinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]24810525
C017803zinc protoporphyrinzinc protoporphyrin inhibits the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]24810525
D019287Zinc SulfateZinc Sulfate inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]16896058
C088658zoledronic acidzoledronic acid results in increased expression of STAT3 mRNA24714768
C424422zoniporidestattic inhibits the reaction [zoniporide results in increased phosphorylation of STAT3 protein]20942815
C424422zoniporidezoniporide results in increased phosphorylation of STAT3 protein20942815
D015054ZymosanIL6 protein affects the reaction [Zymosan results in increased phosphorylation of and results in increased activity of STAT3 protein]15188379
D015054ZymosanZymosan results in increased phosphorylation of and results in increased activity of STAT3 protein15188379

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding-IDA16835372  19390056  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IMP16946298  
GO:0001103RNA polymerase II repressing transcription factor binding-IPI22783022  
GO:0001228transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding-IDA16835372  
GO:0003677DNA binding-ISS-  
GO:0003700DNA-binding transcription factor activity-IDA17344214  
GO:0004879nuclear receptor activity-IDA17324931  
GO:0005515protein binding-IPI8662591  9864141  10688651  11536047  11585385  11940572  
11970898  12867595  14966128  15657067  15764709  15821101  
15998644  16273093  16306601  16331268  16364321  16531398  
16568091  18200042  18234692  18330356  19345327  19372587  
20133729  20826784  20871632  20876300  20929579  21184768  
21516116  21643014  21988832  23416296  23684459  24135280  
24172987  24189400  24396070  24658140  25241761  25402766  
25416956  25417160  25476455  25609649  25814554  26504087  
26966684  28065600  
GO:0008134transcription factor binding-IPI15664994  
GO:0019901protein kinase binding-ISS-  
GO:0019903protein phosphatase binding-IPI12359225  
GO:0031490chromatin DNA binding-IDA17344214  
GO:0031730CCR5 chemokine receptor binding-IEA-  
GO:0035259glucocorticoid receptor binding-IEA-  
GO:0042802identical protein binding-IPI7510216  17676033  21988832  25609649  
GO:0042803protein homodimerization activity-ISS-  
GO:0044212transcription regulatory region DNA binding-IDA17324931  
GO:0046983protein dimerization activity-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-TAS8675499  
GO:0001659temperature homeostasis-ISS-  
GO:0001754eye photoreceptor cell differentiation-ISS-  
GO:0006355regulation of transcription, DNA-templated-IDA15664994  17344214  
GO:0006357regulation of transcription by RNA polymerase II-ISS-  
GO:0006606protein import into nucleus-IDA18234692  
GO:0006953acute-phase response-IEA-  
GO:0006954inflammatory response-ISS-  
GO:0007165signal transduction-TAS7512451  10205054  
GO:0007259JAK-STAT cascade-TAS15664994  
GO:0007399nervous system development-TAS10205054  
GO:0007568aging-IEA-  
GO:0008283cell proliferation-IEA-  
GO:0008285negative regulation of cell proliferation-IEA-  
GO:0010628positive regulation of gene expression-IDA23820254  
GO:0010628positive regulation of gene expression-IMP24255059  
GO:0010730negative regulation of hydrogen peroxide biosynthetic process-IEA-  
GO:0016032viral process-IEA-  
GO:0016310phosphorylation-ISS-  
GO:0019221cytokine-mediated signaling pathway-NAS15664994  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0019953sexual reproduction-ISS-  
GO:0030522intracellular receptor signaling pathway-IDA17324931  
GO:0032355response to estradiol-IDA12552091  
GO:0032870cellular response to hormone stimulus-IDA12552091  
GO:0033210leptin-mediated signaling pathway-IDA17344214  
GO:0035019somatic stem cell population maintenance-TAS-  
GO:0035278miRNA mediated inhibition of translation-IDA23820254  
GO:0035723interleukin-15-mediated signaling pathway-TAS-  
GO:0038111interleukin-7-mediated signaling pathway-TAS-  
GO:0038114interleukin-21-mediated signaling pathway-TAS-  
GO:0038155interleukin-23-mediated signaling pathway-TAS-  
GO:0040014regulation of multicellular organism growth-IEA-  
GO:0042531positive regulation of tyrosine phosphorylation of STAT protein-TAS-  
GO:0042593glucose homeostasis-ISS-  
GO:0042755eating behavior-ISS-  
GO:0042789mRNA transcription by RNA polymerase II-IEA-  
GO:0043066negative regulation of apoptotic process-IMP22984561  
GO:0044320cellular response to leptin stimulus-IDA17344214  
GO:0044321response to leptin-IDA17344214  
GO:0045471response to ethanol-IEA-  
GO:0045648positive regulation of erythrocyte differentiation-IMP28283061  
GO:0045747positive regulation of Notch signaling pathway-ISS-  
GO:0045766positive regulation of angiogenesis-IEA-  
GO:0045820negative regulation of glycolytic process-IEA-  
GO:0045893positive regulation of transcription, DNA-templated-IDA19390056  
GO:0045893positive regulation of transcription, DNA-templated-IMP23066027  
GO:0045893positive regulation of transcription, DNA-templated-ISS-  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA17324931  
GO:0045944positive regulation of transcription by RNA polymerase II-IGI19754877  
GO:0045944positive regulation of transcription by RNA polymerase II-IMP16835372  16946298  
GO:0046902regulation of mitochondrial membrane permeability-IEA-  
GO:0048708astrocyte differentiation-ISS-  
GO:0051726regulation of cell cycle-IDA17344214  
GO:0060019radial glial cell differentiation-ISS-  
GO:0060259regulation of feeding behavior-ISS-  
GO:0060396growth hormone receptor signaling pathway-IDA10925297  
GO:0060397JAK-STAT cascade involved in growth hormone signaling pathway-IDA12552091  
GO:0060397JAK-STAT cascade involved in growth hormone signaling pathway-ISS-  
GO:0070102interleukin-6-mediated signaling pathway-IDA12359225  12552091  17324931  
GO:0070102interleukin-6-mediated signaling pathway-IMP16835372  16946298  
GO:0070102interleukin-6-mediated signaling pathway-TAS-  
GO:0070106interleukin-27-mediated signaling pathway-TAS-  
GO:0070757interleukin-35-mediated signaling pathway-TAS-  
GO:0071345cellular response to cytokine stimulus-TAS-  
GO:0071407cellular response to organic cyclic compound-IEA-  
GO:0072540T-helper 17 cell lineage commitment-ISS-  
GO:0097009energy homeostasis-ISS-  
GO:1901215negative regulation of neuron death-IEA-  
GO:1902728positive regulation of growth factor dependent skeletal muscle satellite cell proliferation-IEA-  
GO:1902895positive regulation of pri-miRNA transcription by RNA polymerase II-IDA19390056  23820254  
GO:1904685positive regulation of metalloendopeptidase activity-IGI23820254  
GO:1905564positive regulation of vascular endothelial cell proliferation-IEA-  
GO:2000637positive regulation of gene silencing by miRNA-IDA23820254  
GO:2000737negative regulation of stem cell differentiation-IEA-  
GO:2001171positive regulation of ATP biosynthetic process-IEA-  
GO:2001223negative regulation of neuron migration-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000790nuclear chromatin-IDA16835372  
GO:0005634nucleus-IDA10336453  12444102  17324931  18234692  22783022  28065600  
GO:0005634nucleus-ISS-  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IDA18234692  22783022  
GO:0005737cytoplasm-ISS-  
GO:0005743mitochondrial inner membrane-IEA-  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
GO:0005886plasma membrane-ISS-  
GO:0090575RNA polymerase II transcription factor complex-IC16835372  
GO:0090575RNA polymerase II transcription factor complex-IMP16946298  
KEGG ID KEGG Term
hsa04062Chemokine signaling pathway
hsa04630Jak-STAT signaling pathway
hsa04920Adipocytokine signaling pathway
hsa05145Toxoplasmosis
hsa05160Hepatitis C
hsa05200Pathways in cancer
hsa05212Pancreatic cancer
hsa05221Acute myeloid leukemia
Reactome ID Reactome Term Evidence
R-HSA-1059683Interleukin-6 signalingTAS
R-HSA-109581ApoptosisTAS
R-HSA-109606Intrinsic Pathway for ApoptosisTAS
R-HSA-111453BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 membersTAS
R-HSA-1226099Signaling by FGFR in diseaseTAS
R-HSA-1266695Interleukin-7 signalingTAS
R-HSA-1266695Interleukin-7 signalingIEA
R-HSA-1266738Developmental BiologyTAS
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-1280215Cytokine Signaling in Immune systemIEA
R-HSA-1433557Signaling by SCF-KITTAS
R-HSA-162582Signal TransductionIEA
R-HSA-162582Signal TransductionTAS
R-HSA-1643685DiseaseTAS
R-HSA-166520Signaling by NTRKsIEA
R-HSA-168256Immune SystemTAS
R-HSA-168256Immune SystemIEA
R-HSA-1839117Signaling by cytosolic FGFR1 fusion mutantsTAS
R-HSA-1839124FGFR1 mutant receptor activationTAS
R-HSA-186763Downstream signal transductionTAS
R-HSA-186797Signaling by PDGFTAS
R-HSA-187037Signaling by NTRK1 (TRKA)IEA
R-HSA-198745Signalling to STAT3IEA
R-HSA-2262752Cellular responses to stressTAS
R-HSA-2559582Senescence-Associated Secretory Phenotype (SASP)TAS
R-HSA-2559583Cellular SenescenceTAS
R-HSA-2586552Signaling by LeptinIEA
R-HSA-2892247POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferationTAS
R-HSA-390466Chaperonin-mediated protein foldingIEA
R-HSA-390471Association of TriC/CCT with target proteins during biosynthesisIEA
R-HSA-391251Protein foldingIEA
R-HSA-392499Metabolism of proteinsIEA
R-HSA-446652Interleukin-1 family signalingTAS
R-HSA-447115Interleukin-12 family signalingTAS
R-HSA-447115Interleukin-12 family signalingIEA
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-449147Signaling by InterleukinsIEA
R-HSA-451927Interleukin-2 family signalingTAS
R-HSA-452723Transcriptional regulation of pluripotent stem cellsTAS
R-HSA-5357801Programmed Cell DeathTAS
R-HSA-5655302Signaling by FGFR1 in diseaseTAS
R-HSA-5663202Diseases of signal transductionTAS
R-HSA-6783589Interleukin-6 family signalingTAS
R-HSA-6783783Interleukin-10 signalingTAS
R-HSA-6785807Interleukin-4 and 13 signalingTAS
R-HSA-6806834Signaling by METIEA
R-HSA-6806834Signaling by METTAS
R-HSA-8848021Signaling by PTK6IEA
R-HSA-8848021Signaling by PTK6TAS
R-HSA-8849474PTK6 Activates STAT3IEA
R-HSA-8849474PTK6 Activates STAT3TAS
R-HSA-8854691Interleukin-20 family signalingTAS
R-HSA-8875791MET activates STAT3IEA
R-HSA-8875791MET activates STAT3TAS
R-HSA-8953897Cellular responses to external stimuliTAS
R-HSA-8983432Interleukin-15 signalingTAS
R-HSA-8984722Interleukin-35 SignallingTAS
R-HSA-9006927Signaling by Non-Receptor Tyrosine KinasesIEA
R-HSA-9006927Signaling by Non-Receptor Tyrosine KinasesTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesIEA
R-HSA-9006934Signaling by Receptor Tyrosine KinasesTAS
R-HSA-9008059Interleukin-37 signalingTAS
R-HSA-9020933Interleukin-23 signalingTAS
R-HSA-9020933Interleukin-23 signalingIEA
R-HSA-9020956Interleukin-27 signalingTAS
R-HSA-9020958Interleukin-21 signalingTAS
R-HSA-982772Growth hormone receptor signalingIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26253658M2 polarized macrophages induced by CSE promote proliferation, migration, and invasion of alveolar basal epithelial cells. (2015 Sep)Fu XInt Immunopharmacol
25104439Genetic variation in the JAK/STAT/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin/NSAIDs: the Breast Cancer Health Disparities Study. (2014 Aug)Slattery MLBreast Cancer Res Treat
24046282Analyses of synovial tissues from arthritic and protected congenic rat strains reveal a new core set of genes associated with disease severity. (2013 Nov 15)Brenner MPhysiol Genomics
28750889Reciprocal activation of alpha5-nAChR and STAT3 in nicotine-induced human lung cancer cell proliferation. (2017 Jul 20)Zhang YJ Genet Genomics
20943775alpha4beta2 nicotinic receptors partially mediate anti-inflammatory effects through Janus kinase 2-signal transducer and activator of transcription 3 but not calcium or cAMP signaling. (2011 Jan)Hosur VMol Pharmacol
19046792Differential ErbB receptor expression and intracellular signaling activity in lung adenocarcinomas and squamous cell carcinomas. (2009 Jul)Lopez-Malpartida AVLung Cancer
20106947Long-term nicotine exposure-induced chemoresistance is mediated by activation of Stat3 and downregulation of ERK1/2 via nAChR and beta-adrenoceptors in human bladder cancer cells. (2010 May)Chen RJToxicol Sci
28802862MicroRNA-21: Expression in oligodendrocytes and correlation with low myelin mRNAs in depression and alcoholism. (2017 Oct 3)Miguel-Hidalgo JJProg Neuropsychopharmacol Biol Psychiatry
22614008Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through alpha7nAChR-mediated MUC4 upregulation. (2013 Mar 14)Momi NOncogene
23717691Myeloid clusters are associated with a pro-metastatic environment and poor prognosis in smoking-related early stage non-small cell lung cancer. (2013)Zhang WPLoS One
27022745Interaction between STAT3 gene polymorphisms and smoking on Crohn's disease susceptibility: a case-control study in a Chinese Han population. (2016 Jul)Li JHInflamm Res
26289596Smoking, inflammation and small cell lung cancer: recent developments. (2015 Oct)Hamilton GWien Med Wochenschr
22394639[Expression of pSTAT3 in non-small cell lung cancer and its clinical significance]. (2012 Mar)Wang RJXi Bao Yu Fen Zi Mian Yi Xue Za Zhi
23193966Contribution of JAK2 and STAT3 variants to the genetic susceptibility of recurrent spontaneous miscarriage in a Tunisian population. (2013 Jan)Messaoudi SGenet Test Mol Biomarkers
27181202SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer. (2016 Nov 10)Zhou ZOncogene
27709266Nicotine protects against DSS colitis through regulating microRNA-124 and STAT3. (2017 Feb)Qin ZJ Mol Med (Berl)
19698101Induction of the interleukin 6/ signal transducer and activator of transcription pathway in the lungs of mice sub-chronically exposed to mainstream tobacco smoke. (2009 Aug 21)Halappanavar SBMC Med Genomics
27994590Cigarette Smoke Induction of Interleukin-27/WSX-1 Regulates the Differentiation of Th1 and Th17 Cells in a Smoking Mouse Model of Emphysema. (2016)Qiu SLFront Immunol
25259522A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via alpha7 nicotinic receptors in human macrophages. (2014)Maldifassi MCPLoS One
27003425Inflammatory and Immune Response Genes Polymorphisms are Associated with Susceptibility to Chronic Obstructive Pulmonary Disease in Tatars Population from Russia. (2016 Aug)Korytina GFBiochem Genet
24727895Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis. (2015 Mar 19)Miller AOncogene
25734337Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. (2015 Mar 3)Grabner BNat Commun
23701918Exposing a deadly alliance: novel insights into the biological links between COPD and lung cancer. (2013 Oct)Vermaelen KPulm Pharmacol Ther
22121102JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. (2013 Feb)Slattery MLMol Carcinog
21752895Variants in STAT5B associate with serum TC and LDL-C levels. (2011 Sep)Kornfeld JWJ Clin Endocrinol Metab
17824789Expression of activated and latent signal transducer and activator of transcription 3 in 303 non-small cell lung carcinomas and 44 malignant mesotheliomas: possible role for chemotherapeutic intervention. (2007 Sep)Achcar Rde OArch Pathol Lab Med
28240520Roles of Signal Transducer Pathways in Investigation of Biopsies from Patients with Bladder Tumors (2017 Jan 1)Bayrak AAsian Pac J Cancer Prev
24267900Social disparities, health risk behaviors, and cancer. (2013)Rametta SBMC Surg
18614255Stat3 downstream genes serve as biomarkers in human lung carcinomas and chronic obstructive pulmonary disease. (2009 Mar)Qu PLung Cancer
28677807Torilis japonica extract fraction compound, EGFR-targeted inhibition of cancer abnormal metastasis in A549 lung cancer cells. (2017 Aug)Kim GTOncol Rep
21609394mTOR-STAT3-notch signalling contributes to ALDH2-induced protection against cardiac contractile dysfunction and autophagy under alcoholism. (2012 Mar)Ge WJ Cell Mol Med
26707655Transgenic mice with increased astrocyte expression of IL-6 show altered effects of acute ethanol on synaptic function. (2016 Apr)Hernandez RVNeuropharmacology
23802852Lung adenocarcinoma biomarker incidence in Hispanic versus non-Hispanic white patients. (2014 Mar)McQuitty EArch Pathol Lab Med
24321995Carbonic anhydrase IX is associated with early pulmonary spreading of primary colorectal carcinoma and tobacco smoking. (2014 Jul)Schweiger TEur J Cardiothorac Surg
16322287Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer. (2005 Dec 1)Haura EBClin Cancer Res
19706765Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition. (2009 Sep 15)Qu PCancer Res
22208386Correlation of activated STAT3 expression with clinicopathologic features in lung adenocarcinoma and squamous cell carcinoma. (2011 Dec 1)Jiang RMol Diagn Ther
25198511Induction of murine macrophage M2 polarization by cigarette smoke extract via the JAK2/STAT3 pathway. (2014)Yuan FPLoS One
27708216Smoking-associated lung cancer prevention by blockade of the beta-adrenergic receptor-mediated insulin-like growth factor receptor activation. (2016 Oct 25)Min HYOncotarget
24486342Glucosamine attenuates cigarette smoke-induced lung inflammation by inhibiting ROS-sensitive inflammatory signaling. (2014 Apr)Wu YLFree Radic Biol Med
29501575Orally administered nicotine effects on rat urinary bladder proliferation and carcinogenesis. (2018 Apr 1)Suzuki SToxicology
25531908The tumor suppressor miR-124 inhibits cell proliferation by targeting STAT3 and functions as a prognostic marker for postoperative NSCLC patients. (2015 Feb)Li XInt J Oncol