Gene: SULT1A1

6817
HAST1/HAST2|P-PST|PST|ST1A1|ST1A3|STP|STP1|TSPST1
sulfotransferase family 1A member 1
protein-coding
16p11.2
Ensembl:ENSG00000196502 MIM:171150 Vega:OTTHUMG00000131765 UniprotKB:P50225
NG_028128.1
PubMed
OD|ND
39   
5.050e-1 (AD)  2.578e-1 (ND)   (Frontal_Cortex)
3.650e-1 (AD)  7.791e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KLHDC90.809
RNF2150.808
ARFGAP20.798
GPS10.797
PCYT20.796
TMEM90.796
COQ40.796
UROD0.794
MRPL20.794
C11orf490.792

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.603
OR4F29-0.558
MTRNR2L9-0.377
PPBP-0.371
TFPI2-0.367
KIAA0040-0.366
MTRNR2L6-0.358
GDNF-0.354
PABPC4L-0.353
SHISA3-0.349

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01812Adenosine-3'-5'-DiphosphateSmall MoleculeExperimentalTarget
DB04417P-NitrophenolSmall Molecule100-02-7ExperimentalTarget
DB00316AcetaminophenSmall Molecule103-90-2ApprovedEnzyme
DB00675TamoxifenSmall Molecule10540-29-1ApprovedEnzyme
DB09070TiboloneSmall Molecule5630-53-5Approved|InvestigationalEnzyme
DB11077Polyethylene glycol 400Small Molecule25322-68-3ApprovedEnzyme
ID Drug Name Action PubMed
C5768821-(2-trifluoromethoxyphenyl)-2-nitroethanone1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in decreased expression of SULT1A1 protein22527513
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of SULT1A1 mRNA"15004031
C0330201-aminobenzotriazole1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]25243916
C0658331-hydroxymethylpyrenePentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene]25243916
C0658331-hydroxymethylpyrene[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene25243916
C0658331-hydroxymethylpyrene[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene25243916
C0658331-hydroxymethylpyrene[SULT1A1 protein co-treated with PAPSS1 protein] results in increased activity of 1-hydroxymethylpyrene24802129
C0658331-hydroxymethylpyreneSULT1A1 protein results in increased activity of 1-hydroxymethylpyrene24802129
C0658331-hydroxymethylpyreneSULT1A1 protein results in increased activity of 1-hydroxymethylpyrene24802129
C0658331-hydroxymethylpyreneSULT1A1 protein results in increased sulfation of 1-hydroxymethylpyrene24802129
C0331461-hydroxypyrene1-hydroxypyrene results in decreased activity of SULT1A1 protein14570759
C0331461-hydroxypyreneacetonitrile inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]14570759
C0331461-hydroxypyreneDimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]14570759
C0331461-hydroxypyreneDimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]14570759
C0331461-hydroxypyreneEthanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]14570759
C0331461-hydroxypyreneEthanol promotes the reaction [1-hydroxypyrene results in decreased activity of SULT1A1 protein]14570759
C0331461-hydroxypyreneMethanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]14570759
C0331461-hydroxypyreneSULT1A1 protein results in increased metabolism of 1-hydroxypyrene24140465
C0331461-hydroxypyreneSULT1A1 protein results in increased sulfation of 1-hydroxypyrene14570759
C0647011-methoxy-3-indolylmethylglucosinolateSULT1A1 protein results in increased susceptibility to 1-methoxy-3-indolylmethylglucosinolate metabolite20846518
C0530351-methylpyrene1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]25243916
C0530351-methylpyrenePentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]25243916
C0530351-methylpyrene[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene25243916|2791384
C0530351-methylpyrene[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene25243916
C0293501-naphtholSULT1A1 protein results in increased sulfation of 1-naphthol14508638
C0293501-naphtholSULT1A1 protein results in increased sulfation of 1-naphthol15684482
C0166141-nitronaphthalene1-nitronaphthalene metabolite binds to SULT1A1 protein16453347
C4838392,2',3,4,4',5',6-heptabromodiphenyl ether"2,2',3,4,4',5',6-heptabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]"16601080
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]"16601080
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl affects the expression of SULT1A1 mRNA"19114083
C5411322,4,4',5-tetrachlorobiphenyl"[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2,4,4',5-tetrachlorobiphenyl"27913846
C5411322,4,4',5-tetrachlorobiphenyl"[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2,4,4',5-tetrachlorobiphenyl] which results in increased mutagenesis of HPRT1 gene"27913846
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of SULT1A1 mRNA"9566755
C0094072,5,2',5'-tetrachlorobiphenyl"[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2,5,2',5'-tetrachlorobiphenyl"27913846
C0094072,5,2',5'-tetrachlorobiphenyl"[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2,5,2',5'-tetrachlorobiphenyl] which results in increased mutagenesis of HPRT1 gene"27913846
C0109252,5-dihydroxybenzoic acid"2,5-dihydroxybenzoic acid results in increased activity of SULT1A1 protein"16308312
C0109252,5-dihydroxybenzoic acid"2,5-dihydroxybenzoic acid results in increased activity of SULT1A1 protein"16443358
C0109252,5-dihydroxybenzoic acid"2,5-dihydroxybenzoic acid results in increased expression of SULT1A1 mRNA"16443358
C0158022,6-dichloro-4-nitrophenol"2,6-dichloro-4-nitrophenol inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]"11425650|1553151
C0158022,6-dichloro-4-nitrophenol"2,6-dichloro-4-nitrophenol results in decreased activity of SULT1A1 protein"10692228
C0158022,6-dichloro-4-nitrophenol"[2,6-dichloro-4-nitrophenol results in decreased activity of SULT1A1 protein] which results in decreased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"10692228
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of SULT1A1 mRNA"21346803
C0775842-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"SULT1A1 protein results in increased sulfation of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"11181495
C0775842-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"SULT1A1 protein results in increased sulfation of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"11181495
C0775842-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"SULT1A1 protein results in increased sulfation of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"11181495
C5022392-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct"[SULT1A1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct"26940682
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"SULT1A1 protein promotes the reaction [[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of APRT gene] which affects the susceptibility to 8-azaadenine]"10692228
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[2,6-dichloro-4-nitrophenol results in decreased activity of SULT1A1 protein] which results in decreased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"10692228
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SULT1A1 protein results in increased sulfation of Estradiol]"17433394
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of SULT1A1 mRNA"22138251
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[SULT1A1 protein co-treated with SULT1A2 protein] results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"22006426
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"SULT1A1 protein results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"21900212|2200642
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"SULT1A1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"26940682
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[SULT1A1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct"26940682
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"SULT1A1 protein results in increased metabolism of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"14973106
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"SULT1A1 protein results in increased metabolism of and results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"28160022
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"SULT1A1 protein results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"10692228
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of SULT1A1 mRNA"15059925
C0178212-amino-3-methyl-9H-pyrido(2,3-b)indole"SULT1A1 protein results in increased activity of and results in increased sulfation of 2-amino-3-methyl-9H-pyrido(2,3-b)indole"14729582
C0178212-amino-3-methyl-9H-pyrido(2,3-b)indole"SULT1A1 protein results in increased metabolism of and results in increased susceptibility to 2-amino-3-methyl-9H-pyrido(2,3-b)indole"28160022
C0352082-amino-4,6-dinitrotoluene"2-amino-4,6-dinitrotoluene affects the expression of SULT1A1 mRNA"21346803
C0237852-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole"SULT1A1 protein results in increased metabolism of and results in increased susceptibility to 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole"28160022
C0178222-amino-9H-pyrido(2,3-b)indole"SULT1A1 protein results in increased metabolism of and results in increased susceptibility to 2-amino-9H-pyrido(2,3-b)indole"28160022
C0605332-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"SULT1A1 protein results in increased metabolism of and results in increased activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"12067565
C0013902-hydroxyestradiolSULT1A1 gene polymorphism affects the sulfation of 2-hydroxyestradiol16517757
C0013902-hydroxyestradiolSULT1A1 protein results in increased sulfation of 2-hydroxyestradiol16517757
C0228302-methoxyestradiolSULT1A1 gene polymorphism affects the sulfation of 2-methoxyestradiol16517757
C0228302-methoxyestradiolSULT1A1 protein results in increased sulfation of 2-methoxyestradiol16517757
C0290602-methylfuranSULT1A1 protein results in increased chemical synthesis of 2-methylfuran metabolite25053625
C0284052-naphthol2-naphthol results in increased activity of SULT1A1 protein8890738
C0005975702-sulfoxymethylfuranSULT1A1 protein results in increased chemical synthesis of 2-sulfoxymethylfuran25053625
C0005975702-sulfoxymethylfuranSULT1A1 protein results in increased chemical synthesis of 2-sulfoxymethylfuran25053625
C0299063,3'-dichlorobiphenyl"SULT1A1 protein results in increased sulfation of 3,3'-dichlorobiphenyl metabolite"23584369
C0306293,3'-diiodothyronine"3,3'-diiodothyronine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]"15531517
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SULT1A1 mRNA"19692669|2319667
C5815813,4-dichlorinated biphenyl"SULT1A1 protein results in increased sulfation of 3,4-dichlorinated biphenyl metabolite"23584369
C0191333-amino-1-methyl-5H-pyrido(4,3-b)indole"SULT1A1 protein results in increased metabolism of and results in increased susceptibility to 3-amino-1-methyl-5H-pyrido(4,3-b)indole"28160022
C0213383-hydroxybenzo(a)pyrenePolychlorinated Biphenyls metabolite inhibits the reaction [SULT1A1 protein polymorphism results in increased sulfation of 3-hydroxybenzo(a)pyrene]15929889
C1172203-nitrobenzanthrone[NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone20545351
C1172203-nitrobenzanthrone[SULT1A1 protein co-treated with 3-nitrobenzanthrone] results in increased mutagenesis of HPRT1 gene17483118
C1172203-nitrobenzanthroneSULT1A1 protein results in increased activity of 3-nitrobenzanthrone15805261
C1172203-nitrobenzanthroneSULT1A1 protein results in increased susceptibility to 3-nitrobenzanthrone17483118
C1172203-nitrobenzanthroneSULT1A1 gene mutant form results in decreased metabolism of 3-nitrobenzanthrone27557898
C0312853-xylene3-xylene results in decreased expression of SULT1A1 mRNA12815608
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C0067574-biphenylamine4-biphenylamine inhibits the reaction [SULT1A1 protein results in increased sulfation of Estradiol]17433394
C0069834-chlorobiphenylSULT1A1 protein results in increased sulfation of 4-chlorobiphenyl metabolite23584369
C0325384-cresolSULT1A1 protein results in increased metabolism of 4-cresol11301044
C0381934-hydroxybenzoic acid4-hydroxybenzoic acid results in increased activity of SULT1A1 protein16308312
C0248364-nitrophenol"2,6-dichloro-4-nitrophenol inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]"11425650|1553151
C0248364-nitrophenol"3,3'-diiodothyronine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]"15531517
C0248364-nitrophenol4-nitrophenol inhibits the reaction [SULT1A1 protein results in decreased sulfation of bisphenol A]12206822
C0248364-nitrophenolacetonitrile inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]14570759
C0248364-nitrophenolChlorophenols analog inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]16413005
C0248364-nitrophenoldaidzein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]15531517
C0248364-nitrophenolDimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]14570759
C0248364-nitrophenolDimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]14570759
C0248364-nitrophenolEthanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]14570759
C0248364-nitrophenolGenistein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]15531517
C0248364-nitrophenolMethanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]14570759
C0248364-nitrophenolPolychlorinated Biphenyls analog inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]16413005
C0248364-nitrophenolSodium Chloride inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]11425650|1553151
C0248364-nitrophenolSULT1A1 gene polymorphism affects the sulfation of 4-nitrophenol15516026|1651775
C0248364-nitrophenolSULT1A1 protein results in increased metabolism of 4-nitrophenol10623578
C0248364-nitrophenolSULT1A1 protein results in increased sulfation of 4-nitrophenol11181495|1457075
C0248364-nitrophenolThyroxine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]15531517
C0248364-nitrophenolTriiodothyronine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]15531517
C0248364-nitrophenol"Triiodothyronine, Reverse inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]"15531517
C0248364-nitrophenolSULT1A1 protein results in increased sulfation of 4-nitrophenol11181495
C0248364-nitrophenolSULT1A1 protein results in increased sulfation of 4-nitrophenol11181495
C0415944-nonylphenolSULT1A1 protein results in increased metabolism of 4-nonylphenol10623578
C0804174-octylphenolSULT1A1 protein results in increased metabolism of 4-octylphenol10623578
C0267855-hydroxyindoleSULT1A1 protein results in increased sulfation of 5-hydroxyindole11181495
C0267855-hydroxyindoleSULT1A1 protein results in increased sulfation of 5-hydroxyindole11181495
C0267855-hydroxyindoleSULT1A1 protein results in increased sulfation of 5-hydroxyindole11181495
C0080465-hydroxymethylfurfural5-hydroxymethylfurfural affects the activity of SULT1A1 protein22563731
C0080465-hydroxymethylfurfuralSULT1A1 protein affects the metabolism of 5-hydroxymethylfurfural22349055
C0080465-hydroxymethylfurfural[SULT1A1 protein co-treated with SULT1A2 protein] results in increased susceptibility to 5-hydroxymethylfurfural22006426
C0080465-hydroxymethylfurfuralSULT1A1 protein results in increased activity of 5-hydroxymethylfurfural22006426
C0080465-hydroxymethylfurfuralSULT1A1 protein results in increased metabolism of 5-hydroxymethylfurfural25370010
C0080465-hydroxymethylfurfuralSULT1A1 protein results in increased metabolism of 5-hydroxymethylfurfural25370010
C0080465-hydroxymethylfurfuralSULT1A1 protein results in increased metabolism of 5-hydroxymethylfurfural25370010
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C0123656-hydroxymelatoninMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of 6-hydroxymelatonin]11181495
C0123656-hydroxymelatoninMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of 6-hydroxymelatonin]11181495
C0123656-hydroxymelatoninMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of 6-hydroxymelatonin]11181495
C0314777-hydroxycoumarinSULT1A1 protein results in increased sulfation of 7-hydroxycoumarin11181495
C0314777-hydroxycoumarinSULT1A1 protein results in increased sulfation of 7-hydroxycoumarin11181495
C0314777-hydroxycoumarinSULT1A1 protein results in increased sulfation of 7-hydroxycoumarin11181495
C0066548-azaadenine"SULT1A1 protein promotes the reaction [[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of APRT gene] which affects the susceptibility to 8-azaadenine]"10692228
C4210109-(4'-aminophenyl)-9H-pyrido(3,4-b)indole"SULT1A1 protein results in increased metabolism of and results in increased susceptibility to 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole"28160022
D000082AcetaminophenAcetaminophen results in decreased expression of SULT1A1 mRNA29067470
D000082AcetaminophenAcetaminophen results in decreased expression of SULT1A1 protein29067470
D000082AcetaminophenAcetaminophen results in decreased expression of SULT1A1 mRNA26772156
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of SULT1A1 mRNA17585979
D000082Acetaminophenhyperoside inhibits the reaction [Acetaminophen results in decreased expression of SULT1A1 mRNA]26772156
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SULT1A1 mRNA]17585979
D000082AcetaminophenAcetaminophen affects the expression of SULT1A1 mRNA18246545
D000082AcetaminophenAcetaminophen results in decreased expression of SULT1A1 mRNA18246545
C032159acetonitrileacetonitrile inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]14570759
C032159acetonitrileacetonitrile inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]14570759
C032159acetonitrileacetonitrile results in decreased activity of SULT1A1 protein14570759
C010840adenosine 3'-phosphate-5'-phosphateGlutathione Disulfide affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]21130751
C010840adenosine 3'-phosphate-5'-phosphateGlutathione Disulfide affects the reaction [Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]]21130751
C010840adenosine 3'-phosphate-5'-phosphatePolychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]21130751
C006418adrenocorticotropin zincadrenocorticotropin zinc results in increased expression of SULT1A1 mRNA19920212
C016601afimoxifeneSULT1A1 gene polymorphism affects the sulfation of afimoxifene16517757
C016601afimoxifeneSULT1A1 protein affects the susceptibility to afimoxifene16517757
C016601afimoxifeneSULT1A1 protein results in increased sulfation of afimoxifene16517757
C016601afimoxifeneSULT1A1 protein results in increased susceptibility to afimoxifene16517757
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of SULT1A1 mRNA27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of SULT1A1 mRNA19770486
C518327aloe emodinaloe emodin results in decreased activity of SULT1A1 protein27633141
D000517alpha-Chlorohydrinalpha-Chlorohydrin analog results in decreased expression of SULT1A1 protein26597043
D000588AminesSULT1A1 protein affects the metabolism of Amines15122594
D0150812-NaphthylamineSULT1A1 protein results in increased sulfation of 2-Naphthylamine17433394
D000643Ammonium ChlorideAmmonium Chloride affects the expression of SULT1A1 mRNA16483693
D047310ApigeninSULT1A1 protein SNP results in increased sulfation of Apigenin17293380
C000228aristolochic acid ISULT1A1 protein results in increased metabolism of and results in increased susceptibility to aristolochic acid I27207664
C000228aristolochic acid ISULT1A1 protein results in increased metabolism of and results in increased susceptibility to aristolochic acid I metabolite27207664
C006632arsenic trioxidearsenic trioxide results in increased expression of SULT1A1 mRNA22521957
D001205Ascorbic AcidAscorbic Acid results in decreased expression of SULT1A1 mRNA21144891
C547126AZM551248AZM551248 results in decreased expression of SULT1A1 mRNA22323515
D001554BenzeneSULT1A1 protein results in increased metabolism of Benzene17479406
C076588benzo(a)pyrene-7,8-dione"SULT1A1 protein results in increased metabolism of benzo(a)pyrene-7,8-dione"22782890
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased expression of SULT1A1 mRNA26377693
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of SULT1A1 mRNA15240111
D019324beta-Naphthoflavonebeta-Naphthoflavone results in decreased expression of SULT1A1 mRNA9566755
D001564Benzo(a)pyreneSULT1A1 protein results in increased sulfation of Benzo(a)pyrene11181495
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of SULT1A1 mRNA19770486
D001564Benzo(a)pyrene"[lipopolysaccharide, E coli O55-B5 co-treated with Benzo(a)pyrene] affects the expression of SULT1A1 mRNA"28987381
D001564Benzo(a)pyreneSULT1A1 protein results in increased sulfation of Benzo(a)pyrene11181495
D001564Benzo(a)pyreneSULT1A1 protein results in increased sulfation of Benzo(a)pyrene11181495
D019905Benzyl AlcoholSULT1A1 protein results in increased sulfation of Benzyl Alcohol26663444
D004958Estradiol"2,2',3,4,4',5',6-heptabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]"16601080
D004958Estradiol"2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]"16601080
D004958Estradiol"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SULT1A1 protein results in increased sulfation of Estradiol]"17433394
D004958Estradiol4-biphenylamine inhibits the reaction [SULT1A1 protein results in increased sulfation of Estradiol]17433394
D004958EstradiolHalogenated Diphenyl Ethers analog inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D004958EstradiolN-hydroxy-4-aminobiphenyl inhibits the reaction [SULT1A1 protein results in increased sulfation of Estradiol]17433394
D004958Estradiolpentabrominated diphenyl ether 100 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D004958EstradiolPentachlorophenol inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D004958EstradiolSULT1A1 gene polymorphism affects the sulfation of Estradiol16517757
D004958EstradiolSULT1A1 protein results in increased sulfation of Estradiol11181495|1651775
D004958Estradioltetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D004958Estradioltribromodiphenyl ether 28 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D004958EstradiolSULT1A1 protein results in increased sulfation of Estradiol11181495
D004958EstradiolSULT1A1 protein results in increased sulfation of Estradiol11181495
C044887beta-methylcholinebeta-methylcholine affects the expression of SULT1A1 mRNA21179406
C095105bexarotenebexarotene results in decreased expression of SULT1A1 mRNA16648578
C004541biochanin Abiochanin A results in increased expression of SULT1A1 mRNA20391625
C004541biochanin Abiochanin A results in increased expression of SULT1A1 protein20391625
C002791bismuth tripotassium dicitratebismuth tripotassium dicitrate results in decreased expression of SULT1A1 mRNA15912405
C006780bisphenol A4-nitrophenol inhibits the reaction [SULT1A1 protein results in decreased sulfation of bisphenol A]12206822
C006780bisphenol AQuercetin inhibits the reaction [SULT1A1 protein results in decreased sulfation of bisphenol A]12206822
C006780bisphenol ASULT1A1 protein results in increased metabolism of bisphenol A10623578
C006780bisphenol ASULT1A1 protein results in increased sulfation of bisphenol A11425650|1220682
C006780bisphenol Abisphenol A results in decreased expression of SULT1A1 mRNA25181051
C006780bisphenol Abisphenol A results in decreased expression of SULT1A1 mRNA26794494
C584509C646 compoundC646 compound results in increased expression of SULT1A1 mRNA26191083
C028031cadmium acetatecadmium acetate affects the expression of SULT1A1 mRNA16249259
C053400cafestol[cafestol co-treated with kahweol] results in decreased activity of SULT1A1 protein15680679
C040048caffeic acidSULT1A1 protein results in increased sulfation of caffeic acid17433394
D002220CarbamazepineCarbamazepine results in decreased expression of SULT1A1 mRNA17381134
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of SULT1A1 mRNA15056808
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of SULT1A1 mRNA15963578
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of SULT1A1 protein12629582
C010063carbonyl sulfidecarbonyl sulfide results in increased expression of SULT1A1 mRNA19395590
D002392CatechinSULT1A1 protein SNP results in increased sulfation of Catechin17293380
C034221catecholSULT1A1 protein results in increased sulfation of catechol17433394
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of SULT1A1 mRNA11323195
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in increased expression of SULT1A1 mRNA26272509
D002733ChlorophenolsChlorophenols analog inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]16413005
D002737ChloropreneChloroprene results in increased expression of SULT1A1 mRNA23125180
D019826Cholic AcidCholic Acid results in increased expression of SULT1A1 mRNA17521389
C043561chrysinSULT1A1 protein SNP results in increased sulfation of chrysin17293380
C027113chrysophanic acidchrysophanic acid results in decreased activity of SULT1A1 protein27633141
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of SULT1A1 mRNA17585979
D002994ClofibrateClofibrate results in decreased expression of SULT1A1 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SULT1A1 mRNA]17585979
D002994ClofibrateClofibrate results in decreased expression of SULT1A1 mRNA21318169
D002994ClofibrateClofibrate results in increased expression of SULT1A1 mRNA11328961
D003022ClotrimazoleClotrimazole results in decreased expression of SULT1A1 mRNA9566755
C018021cobaltous chloridecobaltous chloride results in decreased expression of SULT1A1 mRNA24386269
D009249NADP[NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone20545351
D003345CorticosteroneCorticosterone results in increased expression of SULT1A1 mRNA15755911
D003407CreosoteCreosote results in increased expression of SULT1A1 mRNA19389177
D003513CycloheximideCycloheximide inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 mRNA]16308312
D016572CyclosporineCyclosporine results in decreased expression of SULT1A1 mRNA20106945|2556210
D016572CyclosporineCyclosporine results in decreased expression of SULT1A1 mRNA19770486
C089595cylindrospermopsincylindrospermopsin results in decreased expression of SULT1A1 mRNA23726867
D003609DactinomycinDactinomycin inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 mRNA]16308312
C004742daidzeindaidzein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]15531517
C526360dechlorane plusdechlorane plus results in decreased expression of SULT1A1 mRNA23245762
D003671DEET[fipronil co-treated with DEET] results in increased expression of SULT1A1 mRNA27091632
D013759Dronabinol[Dronabinol co-treated with Ethanol] results in decreased expression of SULT1A1 mRNA17618662
D013759DronabinolDronabinol results in decreased expression of SULT1A1 mRNA17618662
D003907Dexamethasone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SULT1A1 mRNA16054899
D003907DexamethasoneDexamethasone results in increased expression of SULT1A1 mRNA22733784
D003907DexamethasoneDexamethasone affects the expression of SULT1A1 mRNA15102944
D003907DexamethasoneDexamethasone promotes the reaction [EP300 protein binds to SULT1A1 promoter]22465009
D003907DexamethasoneDexamethasone results in increased expression of SULT1A1 mRNA11328961|1510294
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone results in increased expression of SULT1A1 mRNA]9566755
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of SULT1A1 mRNA27392435
D002945CisplatinSULT1A1 protein affects the susceptibility to Cisplatin16217747
D004041Dietary FatsDietary Fats results in decreased expression of SULT1A1 mRNA18042831
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of SULT1A1 mRNA19850644
D004051Diethylhexyl PhthalatePPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SULT1A1 mRNA]19850644
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of SULT1A1 mRNA21318169
C014476diethyl maleatediethyl maleate results in decreased expression of SULT1A1 protein21161181
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of SULT1A1 mRNA18544905
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid] results in increased expression of SULT1A1 mRNA18544905
D004054DiethylstilbestrolSULT1A1 protein results in increased metabolism of Diethylstilbestrol10623578
D004104DiiodothyroninesSULT1A1 gene polymorphism affects the sulfation of Diiodothyronines11739018
D004104DiiodothyroninesSULT1A1 protein results in increased sulfation of Diiodothyronines11739018
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of SULT1A1 mRNA"19480007
D004126DimethylformamideDimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]14570759
D004126DimethylformamideDimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]14570759
D0198131,2-Dimethylhydrazine"1,2-Dimethylhydrazine results in decreased expression of SULT1A1 mRNA"27840820
D004128Dimethylnitrosamine[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to Dimethylnitrosamine27913846
D004128Dimethylnitrosamine[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to Dimethylnitrosamine] which results in increased mutagenesis of HPRT1 gene27913846
D004121Dimethyl SulfoxideDimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]14570759
D004121Dimethyl SulfoxideDimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]14570759
D004237DiuronDiuron results in decreased expression of SULT1A1 mRNA25152437
D004298DopamineMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of Dopamine]11181495
D004298DopamineSULT1A1 protein results in increased metabolism of Dopamine10623578
D004298DopamineMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of Dopamine]11181495
D004298DopamineMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of Dopamine]11181495
D004317DoxorubicinSULT1A1 protein affects the susceptibility to Doxorubicin16217747
D004642EmodinEmodin results in decreased activity of SULT1A1 protein27633141
C118739entinostatentinostat results in increased expression of SULT1A1 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
D004785Environmental PollutantsEnvironmental Pollutants affects the expression of SULT1A1 mRNA19118595
D002393Estrogens, Catechol"SULT1A1 protein results in increased sulfation of and results in decreased activity of Estrogens, Catechol"15455371
D004970EstroneSULT1A1 protein results in increased metabolism of Estrone10623578
D000431EthanolEthanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]14570759
D000431EthanolEthanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]14570759
D000431EthanolEthanol promotes the reaction [1-hydroxypyrene results in decreased activity of SULT1A1 protein]14570759
D000431EthanolEthanol results in decreased activity of SULT1A1 protein14570759
D000431EthanolEthanol results in increased expression of SULT1A1 mRNA19167417
D000431Ethanol[Dronabinol co-treated with Ethanol] results in decreased expression of SULT1A1 mRNA17618662
D000431EthanolEthanol results in increased expression of SULT1A1 mRNA17618662
D004997Ethinyl Estradiol[Quercetin co-treated with SULT1A1 protein] results in decreased sulfation of Ethinyl Estradiol15483196
D004997Ethinyl EstradiolSULT1A1 protein results in increased metabolism of Ethinyl Estradiol10623578
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of SULT1A1 mRNA12655037|1583489
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of SULT1A1 mRNA23649840
C047360felbamatefelbamate results in decreased expression of SULT1A1 mRNA17381134
D005273FenbendazoleFenbendazole affects the expression of SULT1A1 mRNA26366864
C504383fenbuconazolefenbuconazole results in decreased expression of SULT1A1 mRNA15942997
C004999ferulic acidferulic acid results in increased expression of SULT1A1 mRNA16443358
C082360fipronil[fipronil co-treated with DEET] results in increased expression of SULT1A1 mRNA27091632
D005419FlavonoidsSULT1A1 gene polymorphism affects the sulfation of Flavonoids16517757
D005419FlavonoidsSULT1A1 protein results in increased sulfation of Flavonoids16517757
C014558flunixin meglumineflunixin meglumine affects the expression of SULT1A1 mRNA26366864
D005557FormaldehydeFormaldehyde results in increased expression of SULT1A1 mRNA23649840
C039281furanfuran results in decreased expression of SULT1A1 mRNA15120968
C012986furfuryl alcoholSULT1A1 protein results in increased metabolism of furfuryl alcohol25053625|2537001
C012986furfuryl alcoholSULT1A1 protein results in increased metabolism of furfuryl alcohol25053625|2537001
C012986furfuryl alcoholSULT1A1 protein results in increased metabolism of furfuryl alcohol25370010
C040029gabapentingabapentin results in decreased expression of SULT1A1 mRNA17381134
D005707Gallic AcidCycloheximide inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 mRNA]16308312
D005707Gallic AcidDactinomycin inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 mRNA]16308312
D005707Gallic AcidGallic Acid results in increased activity of SULT1A1 protein16308312
D005707Gallic AcidGallic Acid results in increased expression of SULT1A1 protein16308312
D005707Gallic Acidpyrazolanthrone inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 protein]16308312
D005707Gallic AcidSB 203580 inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 protein]16308312
D005707Gallic AcidGallic Acid results in increased activity of SULT1A1 protein16443358
D005707Gallic AcidGallic Acid results in increased expression of SULT1A1 mRNA16443358
D019833GenisteinGenistein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]15531517
D019833GenisteinSULT1A1 protein results in increased sulfation of Genistein17004897
D005839GentamicinsGentamicins results in decreased expression of SULT1A1 mRNA20849911
C023847Glu-P-2SULT1A1 protein results in increased metabolism of and results in increased susceptibility to Glu-P-228160022
D019803Glutathione DisulfideGlutathione Disulfide affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]21130751
D019803Glutathione DisulfideGlutathione Disulfide affects the reaction [Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]]21130751
D019803Glutathione DisulfideGlutathione Disulfide affects the reaction [Polychlorinated Biphenyls analog binds to SULT1A1 protein]21130751
C071834glycidamideglycidamide results in increased expression of SULT1A1 mRNA17822822
C412815GW 4064GW 4064 results in increased expression of SULT1A1 mRNA26655953
D055768Halogenated Diphenyl EthersHalogenated Diphenyl Ethers analog inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
C001326harmolMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of harmol]11181495
C001326harmolMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of harmol]11181495
C001326harmolMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of harmol]11181495
D006533HeptachlorHeptachlor results in decreased expression of SULT1A1 mRNA9566755
D006571Heterocyclic CompoundsSULT1A1 protein affects the metabolism of Heterocyclic Compounds15743503
D006581HexachlorobenzeneHexachlorobenzene results in increased expression of SULT1A1 mRNA15159207
D012701SerotoninSULT1A1 protein results in increased sulfation of Serotonin11181495
D012701SerotoninSULT1A1 protein results in increased sulfation of Serotonin11181495
D012701SerotoninSULT1A1 protein results in increased sulfation of Serotonin11181495
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of SULT1A1 mRNA21179406
D003900DesoxycorticosteroneDesoxycorticosterone promotes the reaction [EP300 protein binds to SULT1A1 promoter]22465009
D006917HydroxytryptopholSULT1A1 protein results in increased sulfation of Hydroxytryptophol11181495
D006917HydroxytryptopholSULT1A1 protein results in increased sulfation of Hydroxytryptophol11181495
D006917HydroxytryptopholSULT1A1 protein results in increased sulfation of Hydroxytryptophol11181495
D006923HymecromoneSULT1A1 protein results in increased sulfation of Hymecromone11181495
D006923HymecromoneSULT1A1 protein results in increased sulfation of Hymecromone11181495
D006923HymecromoneSULT1A1 protein results in increased sulfation of Hymecromone11181495
C021304hyperosidehyperoside inhibits the reaction [Acetaminophen results in decreased expression of SULT1A1 mRNA]26772156
C492448ICG 001ICG 001 results in increased expression of SULT1A1 mRNA26191083
C041508indeno(1,2,3-cd)pyrene"indeno(1,2,3-cd)pyrene results in decreased expression of SULT1A1 mRNA"26377693
D007213IndomethacinIndomethacin results in increased expression of SULT1A1 mRNA18299717
D0150561-Methyl-3-isobutylxanthine[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SULT1A1 mRNA16054899
D007545IsoproterenolIsoproterenol results in increased expression of SULT1A1 mRNA20003209
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of SULT1A1 mRNA27392435
C544151jinfukangjinfukang results in increased expression of SULT1A1 mRNA27392435
C053401kahweol[cafestol co-treated with kahweol] results in decreased activity of SULT1A1 protein15680679
D007649KetamineKetamine results in increased expression of SULT1A1 mRNA20080153
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of SULT1A1 mRNA18544905
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid] results in increased expression of SULT1A1 mRNA18544905
C099406L 742694L 742694 affects the expression of SULT1A1 mRNA15102944
C099406L 742694L 742694 results in decreased expression of SULT1A1 mRNA15102944
C008261lead acetatelead acetate results in increased expression of SULT1A1 mRNA22641619
D008012LidocaineSULT1A1 protein results in increased sulfation of Lidocaine metabolite10460806
D001556LindaneLindane results in decreased expression of SULT1A1 mRNA9566755
C482199lipopolysaccharide, E coli O55-B5"[lipopolysaccharide, E coli O55-B5 co-treated with Benzo(a)pyrene] affects the expression of SULT1A1 mRNA"28987381
D008094LithiumLithium results in decreased expression of SULT1A1 mRNA19949822
D008469Meclofenamic AcidMeclofenamic Acid results in decreased activity of SULT1A1 protein17073578
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of 6-hydroxymelatonin]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of Dopamine]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of harmol]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of naringenin]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of salicylamide]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of 6-hydroxymelatonin]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of Dopamine]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of harmol]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of naringenin]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of salicylamide]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of 6-hydroxymelatonin]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of Dopamine]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of harmol]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of naringenin]11181495
D008528Mefenamic AcidMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of salicylamide]11181495
C042720mercuric bromidemercuric bromide results in increased expression of SULT1A1 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
D008694MethamphetamineMethamphetamine results in increased expression of SULT1A1 mRNA23026138
D008694MethamphetamineMethamphetamine results in increased expression of SULT1A1 protein23026138
D000432MethanolMethanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]14570759
D000432MethanolMethanol inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]14570759
D008701MethapyrileneMethapyrilene results in decreased expression of SULT1A1 mRNA16393664|2327439
D008727MethotrexateMethotrexate affects the expression of SULT1A1 mRNA18502557
D008748MethylcholanthreneMethylcholanthrene results in increased activity of SULT1A1 protein19525444
D008748MethylcholanthreneMethylcholanthrene results in increased expression of SULT1A1 mRNA19525444
D008748MethylcholanthreneMethylcholanthrene results in decreased expression of SULT1A1 mRNA11323195
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of SULT1A1 mRNA23649840
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone results in increased expression of SULT1A1 mRNA]9566755
D008914MinoxidilSULT1A1 protein results in increased sulfation of Minoxidil11181495
D008914MinoxidilSULT1A1 protein results in increased sulfation of Minoxidil11181495
D008914MinoxidilSULT1A1 protein results in increased sulfation of Minoxidil11181495
D009020MorphineMorphine results in increased expression of SULT1A1 mRNA20144693
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of SULT1A1 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog affects the expression of SULT1A1 mRNA"25554681
C031721naphthalenenaphthalene analog results in decreased expression of SULT1A1 mRNA24976557
C005273naringeninMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of naringenin]11181495
C005273naringeninMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of naringenin]11181495
C005273naringeninMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of naringenin]11181495
D018377Neurotransmitter AgentsSULT1A1 protein results in increased sulfation of Neurotransmitter Agents23026138
D019829NevirapineNevirapine metabolite results in increased activity of SULT1A1 protein27417440
D019829NevirapineNevirapine results in increased activity of SULT1A1 protein27417440
C014593N-hydroxy-4-aminobiphenylN-hydroxy-4-aminobiphenyl inhibits the reaction [SULT1A1 protein results in increased sulfation of Estradiol]17433394
C014593N-hydroxy-4-aminobiphenylSULT1A1 protein results in increased sulfation of N-hydroxy-4-aminobiphenyl17433394
C022838nickel chloridenickel chloride affects the expression of SULT1A1 mRNA22110744
C012655nimesulidenimesulide results in decreased activity of SULT1A1 protein17073578
C007350nitrofenSULT1A1 protein results in increased activity of nitrofen14754874
C007350nitrofenSULT1A1 protein results in increased activity of nitrofen14754874
C007350nitrofenSULT1A1 protein results in increased activity of nitrofen14754874
C002741N-nitrosomorpholineN-nitrosomorpholine results in decreased expression of SULT1A1 protein19716841
C025589ochratoxin Aochratoxin A results in increased expression of SULT1A1 mRNA16251485
C014138octachlorostyreneAHR protein inhibits the reaction [octachlorostyrene results in increased activity of SULT1A1 protein]19525444
C014138octachlorostyreneAHR protein inhibits the reaction [octachlorostyrene results in increased expression of SULT1A1 mRNA]19525444
C014138octachlorostyreneoctachlorostyrene results in increased expression of SULT1A1 mRNA19525444
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of SULT1A1 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of SULT1A1 mRNA25729387
D010126OzoneOzone results in increased expression of SULT1A1 mRNA17095637
D000073878Palm OilPalm Oil results in decreased expression of SULT1A1 mRNA18042831
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
C016030pantogabpantogab results in decreased expression of SULT1A1 mRNA17379144
D010278ParathionParathion results in increased activity of SULT1A1 protein15351727
C517827pentabrominated diphenyl ether 100pentabrominated diphenyl ether 100 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D010416PentachlorophenolPentachlorophenol inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D010416PentachlorophenolPentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene]25243916
D010416PentachlorophenolPentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]25243916
C036567perfluorodecanoic acidperfluorodecanoic acid results in decreased expression of SULT1A1 protein8620580
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of SULT1A1 mRNA17681415|1846767
C023036perfluorooctanoic acidPPARA protein affects the reaction [perfluorooctanoic acid results in decreased expression of SULT1A1 mRNA]21318169
C023036perfluorooctanoic acidPPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of SULT1A1 mRNA]18467677
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of SULT1A1 mRNA19162173|2131816
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of SULT1A1 protein8620580
D010634PhenobarbitalPhenobarbital results in decreased expression of SULT1A1 mRNA9566755
D010634PhenobarbitalPhenobarbital results in increased expression of SULT1A1 mRNA19631232
D010636PhenolsSULT1A1 protein results in increased sulfation of Phenols23026138
D010646PhentolamineSULT1A1 protein results in increased sulfation of Phentolamine11181495
D010646PhentolamineSULT1A1 protein results in increased sulfation of Phentolamine11181495
D010646PhentolamineSULT1A1 protein results in increased sulfation of Phentolamine11181495
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of SULT1A1 mRNA26272509
D010672PhenytoinPhenytoin results in decreased expression of SULT1A1 mRNA17381134|9566755
D010724Phosphoadenosine Phosphosulfate"2,2',3,4,4',5',6-heptabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]"16601080
D010724Phosphoadenosine Phosphosulfate"2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]"16601080
D010724Phosphoadenosine PhosphosulfateHalogenated Diphenyl Ethers analog inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D010724Phosphoadenosine Phosphosulfate[NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone20545351
D010724Phosphoadenosine Phosphosulfatepentabrominated diphenyl ether 100 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D010724Phosphoadenosine PhosphosulfatePentachlorophenol inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D010724Phosphoadenosine PhosphosulfateSULT1A1 protein results in increased sulfation of Phosphoadenosine Phosphosulfate11425650
D010724Phosphoadenosine Phosphosulfatetetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D010724Phosphoadenosine Phosphosulfatetribromodiphenyl ether 28 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
C008905physcionephyscione results in decreased activity of SULT1A1 protein27633141
C016063pinocembrinSULT1A1 protein results in increased sulfation of pinocembrin11181495
C016063pinocembrinSULT1A1 protein results in increased sulfation of pinocembrin11181495
C016063pinocembrinSULT1A1 protein results in increased sulfation of pinocembrin11181495
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SULT1A1 mRNA19710929
C006253pirinixic acid[pirinixic acid co-treated with PPARA] results in decreased expression of SULT1A1 mRNA20813756
C006253pirinixic acidpirinixic acid results in decreased expression of SULT1A1 mRNA20059764|2081375
C006253pirinixic acidPPARA protein affects the reaction [pirinixic acid results in decreased expression of SULT1A1 mRNA]21318169
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in decreased expression of SULT1A1 mRNA]20059764
C006253pirinixic acidpirinixic acid results in increased expression of SULT1A1 mRNA19631232
D010894PiroxicamPiroxicam results in decreased activity of SULT1A1 protein17073578
D028321Plant PreparationsPlant Preparations affects the expression of SULT1A1 mRNA16046712
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls affects the expression of SULT1A1 mRNA21334430
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls affects the metabolism of SULT1A1 protein21913674
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls analog inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]16413005
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls metabolite inhibits the reaction [SULT1A1 protein polymorphism results in increased sulfation of 3-hydroxybenzo(a)pyrene]15929889
D011078Polychlorinated BiphenylsGlutathione Disulfide affects the reaction [Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]]21130751
D011078Polychlorinated BiphenylsGlutathione Disulfide affects the reaction [Polychlorinated Biphenyls analog binds to SULT1A1 protein]21130751
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]21130751
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls analog binds to and results in decreased activity of SULT1A1 protein21130751
D011078Polychlorinated BiphenylsSULT1A1 protein results in increased sulfation of Polychlorinated Biphenyls analog21130751
D011084Polycyclic Aromatic HydrocarbonsSULT1A1 protein affects the metabolism of Polycyclic Aromatic Hydrocarbons15122594|1574350
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of SULT1A1 mRNA28903501
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of SULT1A1 mRNA19162173|2131816
D011374ProgesteroneProgesterone results in decreased expression of SULT1A1 mRNA23018184
D011374ProgesteroneProgesterone results in increased expression of SULT1A1 mRNA20726854
C045950propiconazolepropiconazole results in increased expression of SULT1A1 mRNA21278054
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 protein]16308312
C031280pyrazolepyrazole results in decreased expression of SULT1A1 mRNA17945193
C030984pyrenepyrene results in increased expression of and results in increased activity of SULT1A1 protein17618724
C030984pyrenepyrene results in increased expression of SULT1A1 mRNA17618724|2616011
D011794Quercetin[Quercetin co-treated with SULT1A1 protein] results in decreased sulfation of Ethinyl Estradiol15483196
D011794QuercetinQuercetin inhibits the reaction [SULT1A1 protein results in decreased sulfation of bisphenol A]12206822
D011794QuercetinQuercetin results in decreased expression of SULT1A1 mRNA21632981
D011794QuercetinSULT1A1 protein SNP results in increased sulfation of Quercetin17293380
C059514resveratrolresveratrol results in increased expression of SULT1A1 protein22096581
C059514resveratrolSULT1A1 protein results in increased sulfation of resveratrol16418064
C059514resveratrolSULT1A1 protein SNP results in increased sulfation of resveratrol17293380
C020491rheinrhein results in decreased activity of SULT1A1 protein27633141
C037663ropivacaineSULT1A1 protein results in increased sulfation of ropivacaine metabolite10460806
C089730rosiglitazone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SULT1A1 mRNA16054899
C089730rosiglitazonerosiglitazone results in increased expression of SULT1A1 mRNA21172411
C031060salicylamideMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of salicylamide]11181495
C031060salicylamideMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of salicylamide]11181495
C031060salicylamideMefenamic Acid inhibits the reaction [SULT1A1 protein results in increased sulfation of salicylamide]11181495
C093642SB 203580SB 203580 inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 protein]16308312
D012601Scopolamine HydrobromideScopolamine Hydrobromide results in increased expression of SULT1A1 mRNA17540011
C009250sevofluranesevoflurane affects the expression of SULT1A1 mRNA15967596
C009277sodium arsenatesodium arsenate results in increased expression of SULT1A1 mRNA11353140
C017947sodium arsenitesodium arsenite results in increased methylation of SULT1A1 gene24570342
C016104sodium bichromatesodium bichromate affects the expression of SULT1A1 mRNA22110744
D012965Sodium ChlorideSodium Chloride inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]11425650|1553151
D053260SootSoot affects the expression of SULT1A1 mRNA26551751
C075117squalestatin 1squalestatin 1 results in increased expression of SULT1A1 mRNA27225895
C075117squalestatin 1squalestatin 1 results in decreased expression of SULT1A1 mRNA27225895
D014284TriiodothyronineSULT1A1 gene polymorphism affects the sulfation of Triiodothyronine11739018
D014284TriiodothyronineSULT1A1 protein results in increased sulfation of Triiodothyronine11739018
D014284TriiodothyronineTriiodothyronine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]15531517
D014284TriiodothyronineTriiodothyronine results in increased expression of SULT1A1 mRNA19228888
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in decreased expression of SULT1A1 mRNA15885361
C020806tetrabromobisphenol Atetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SULT1A1 mRNA26377647
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of SULT1A1 mRNA25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SULT1A1 gene]28213091
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SULT1A1 mRNA19770486|2629044
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SULT1A1 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SULT1A1 mRNA16497791|1969266
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SULT1A1 protein16497791
D013974ThyroxineSULT1A1 gene polymorphism affects the sulfation of Thyroxine11739018
D013974ThyroxineSULT1A1 protein results in increased sulfation of Thyroxine11739018
D013974ThyroxineThyroxine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]15531517
D013963Thyroid HormonesSULT1A1 protein affects the metabolism of Thyroid Hormones15004031
C009495titanium dioxidetitanium dioxide results in decreased expression of SULT1A1 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of SULT1A1 mRNA28111298
D014051Toluene 2,4-Diisocyanate"SULT1A1 gene polymorphism affects the susceptibility to Toluene 2,4-Diisocyanate"18447907
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of SULT1A1 mRNA25729387
C495469trans-3-(4'-hydroxyphenyl)-2-propenoic acidtrans-3-(4'-hydroxyphenyl)-2-propenoic acid results in increased activity of SULT1A1 protein16308312
C495469trans-3-(4'-hydroxyphenyl)-2-propenoic acidtrans-3-(4'-hydroxyphenyl)-2-propenoic acid results in increased activity of SULT1A1 protein16443358
C495469trans-3-(4'-hydroxyphenyl)-2-propenoic acidtrans-3-(4'-hydroxyphenyl)-2-propenoic acid results in increased expression of SULT1A1 mRNA16443358
D014222Triamcinolone AcetonideTriamcinolone Acetonide results in increased expression of SULT1A1 mRNA10799342
D014222Triamcinolone AcetonideTriamcinolone Acetonide results in increased expression of SULT1A1 protein10799342
C533760tribromodiphenyl ether 28tribromodiphenyl ether 28 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]16601080
C012589trichostatin Atrichostatin A results in increased expression of SULT1A1 mRNA24935251
D014285Triiodothyronine, Reverse"Triiodothyronine, Reverse inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]"15531517
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of SULT1A1 mRNA19042947
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in decreased expression of SULT1A1 mRNA17982090
D014303TrinitrotolueneTrinitrotoluene affects the expression of SULT1A1 mRNA21346803
C057693troglitazoneSULT1A1 protein results in increased sulfation of troglitazone11181495
C057693troglitazoneSULT1A1 protein results in increased sulfation of troglitazone11181495
C057693troglitazoneSULT1A1 protein results in increased sulfation of troglitazone11181495
C057693troglitazonetroglitazone results in decreased expression of SULT1A1 protein21315101
D014502Uranyl NitrateUranyl Nitrate results in increased expression of SULT1A1 mRNA24146111
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in decreased expression of SULT1A1 mRNA15885361
C406224valdecoxibvaldecoxib results in decreased expression of SULT1A1 mRNA24136188
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1A1 mRNA"27188386
D014635Valproic AcidValproic Acid results in increased expression of SULT1A1 mRNA23179753|2493525
D014635Valproic AcidValproic Acid results in decreased expression of SULT1A1 mRNA23665938
D014747VinblastineSULT1A1 protein affects the susceptibility to Vinblastine16217747
C025643vinclozolinvinclozolin affects the expression of SULT1A1 mRNA19015723
C104536xanthohumolxanthohumol results in decreased expression of SULT1A1 mRNA22138251
C104536xanthohumolxanthohumol results in increased expression of SULT1A1 mRNA22138251
D015032ZincZinc results in increased expression of SULT1A1 mRNA17074742
D019287Zinc SulfateZinc Sulfate results in increased expression of SULT1A1 mRNA17074742

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004062aryl sulfotransferase activity-IDA12471039  23207770  
GO:0004062aryl sulfotransferase activity-TAS-  
GO:0005515protein binding-IPI25416956  25910212  
GO:0008146sulfotransferase activity-IDA19548878  
GO:0047894flavonol 3-sulfotransferase activity-IDA20056724  
GO:0050294steroid sulfotransferase activity-IDA16221673  
GO ID GO Term Qualifier Evidence PubMed
GO:0006068ethanol catabolic process-IDA23207770  
GO:0006584catecholamine metabolic process-IEA-  
GO:0006805xenobiotic metabolic process-IDA12471039  20056724  
GO:0008210estrogen metabolic process-IDA16221673  
GO:0009308amine metabolic process-TAS8661000  
GO:0009812flavonoid metabolic process-IDA20056724  
GO:00504273'-phosphoadenosine 5'-phosphosulfate metabolic process-IDA23207770  
GO:00504273'-phosphoadenosine 5'-phosphosulfate metabolic process-TAS-  
GO:0051923sulfation-IDA19548878  20056724  23207770  
GO ID GO Term Qualifier Evidence PubMed
GO:0005829cytosol-TAS-  
KEGG ID KEGG Term
hsa00920Sulfur metabolism
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-156580Phase II - Conjugation of compoundsTAS
R-HSA-156584Cytosolic sulfonation of small moleculesTAS
R-HSA-211859Biological oxidationsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
14520706Interactions between genetic polymorphism of cytochrome P450-1B1, sulfotransferase 1A1, catechol-o-methyltransferase and tobacco exposure in breast cancer risk. (2003 Nov 20)Saintot MInt J Cancer
28589969Combined effects of NQO1 Pro187Ser or SULT1A1 Arg213His polymorphism and smoking on bladder cancer risk: Two meta-analyses. (2017 Jul 14)Wang XCInt J Occup Med Environ Health
19126640Sulfotransferase 1A1 haplotypes associated with oral squamous cell carcinoma susceptibility in male Taiwanese. (2009 Feb)Chung YTCarcinogenesis
19120511Genetic polymorphism of sulfotransferase 1A1, cigarette smoking, hazardous chemical exposure and urothelial cancer risk in a Taiwanese population. (2008 Dec)Wang YHInt J Urol
23159782The effect of cigarette smoke and arsenic exposure on urothelial carcinoma risk is modified by glutathione S-transferase M1 gene null genotype. (2013 Jan 15)Chung CJToxicol Appl Pharmacol
12468438CYP1A1*2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated with FLT3 internal tandem duplication. (2003 Apr 1)Bowen DTBlood
21791872Association between cancer risk and drug-metabolizing enzyme gene (CYP2A6, CYP2A13, CYP4B1, SULT1A1, GSTM1, and GSTT1) polymorphisms in cases of lung cancer in Japan. (2011)Tamaki YDrug Metab Pharmacokinet
16504378Does occupational exposure to PAHs, diesel and aromatic amines interact with smoking and metabolic genetic polymorphisms to increase the risk on bladder cancer?; The Belgian case control study on bladder cancer risk. (2007 Jan 8)Kellen ECancer Lett
14601045Genetic polymorphisms and modulation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adducts in human lymphocytes. (2003 Dec 20)Magagnotti CInt J Cancer
16926176Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps. (2007 Feb)Goode ELCarcinogenesis
15122594GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high-risk population. (2004 Jul 1)Hung RJInt J Cancer
14618622Effect of SULT1A1 and NAT2 genetic polymorphism on the association between cigarette smoking and colorectal adenomas. (2004 Jan 1)Tiemersma EWInt J Cancer
29110586Genetic variants of SULT1A1 and XRCC1 genes and risk of lung cancer in Bangladeshi population. (2017 Nov)Tasnim TTumour Biol
16272171Gene-environment interaction: the role of SULT1A1 and CYP3A5 polymorphisms as risk modifiers for squamous cell carcinoma of the oesophagus. (2006 Apr)Dandara CCarcinogenesis
24307569Maternal genetic polymorphisms of phase II metabolic enzymes and the risk of fetal neural tube defects. (2014 Jan)Wang LBirth Defects Res A Clin Mol Teratol
22524828SULT1A1 Arg213His polymorphism and lung cancer risk: a meta-analysis. (2012)Liao SGAsian Pac J Cancer Prev
25194687SULT1A1 Arg213His polymorphism is associated with bladder cancer risk: a meta-analysis. (2014 Sep 7)Li WMed Sci Monit
17619904Human NAD(P)H:quinone oxidoreductase 1 (NQO1) and sulfotransferase 1A1 (SULT1A1) polymorphisms and urothelial cancer risk in Taiwan. (2008 Feb)Wang YHJ Cancer Res Clin Oncol
21670965SULT1A1 Arg213His polymorphism and susceptibility of environment-related cancers: a meta analysis of 5,915 cases and 7,900 controls. (2012 Mar)Li KMol Biol Rep
25469277Quantitative analysis of the association between sulfotransferase isoform 1A1 polymorphism and risk of urothelial carcinoma. (2015 Jan)Liu KMol Clin Oncol
20937634Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk. (2010 Nov 1)Cleary SPAm J Epidemiol
12455060SULT1A1 polymorphism and esophageal cancer in males. (2003 Jan 1)Wu MTInt J Cancer
17603900Case-only study of interactions between metabolic enzymes and smoking in colorectal cancer. (2007 Jun 30)Fan CBMC Cancer
12402313Association of genotypes of carcinogen-activating enzymes, phenol sulfotransferase SULT1A1 (ST1A3) and arylamine N-acetyltransferase NAT2, with urothelial cancer in a Japanese population. (2002 Dec 1)Ozawa SInt J Cancer
15743503SULT1A1 genotype, active and passive smoking, and breast cancer risk by age 50 years in a German case-control study. (2005)Lilla CBreast Cancer Res
18499698Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer. (2008 Jun)Suzuki HCarcinogenesis
17996038Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: a case-control study in an Italian population. (2007 Nov 8)Boccia SBMC Cancer
17274372[A case-control study on the association between the genetic polymorphism of sulfotransferase 1A1, diet and susceptibility of colorectal cancer]. (2006 Sep)Chen KZhonghua Zhong Liu Za Zhi
17013894SULT1A1 genotype and susceptibility to colorectal cancer. (2007 Jan 1)Lilla CInt J Cancer
25103078Combined effects of GSTO1 and SULT1A1 polymorphisms and cigarette smoking on urothelial carcinoma risk in a Taiwanese population. (2014 Sep)Tung MCJ Formos Med Assoc
14648207Cytochrome P450 (CYP) 1A2, sulfotransferase (SULT) 1A1, and N-acetyltransferase (NAT) 2 polymorphisms and susceptibility to urothelial cancer. (2004 Feb)Tsukino HJ Cancer Res Clin Oncol
17912498Sulfotransferase 1A1 and glutathione S-transferase P1 genetic polymorphisms modulate the levels of urinary 8-hydroxy-2'-deoxyguanosine in betel quid chewers. (2008 May)Wong RHArch Toxicol
23197595Steroidogenic enzyme expression in the human fetal liver and potential role in the endocrinology of pregnancy. (2013 Mar)O'Shaughnessy PJMol Hum Reprod
14643027Sulfotransferase 1A1 (SULT1A1) polymorphism and bladder cancer risk: a case-control study. (2003 Dec 8)Zheng LCancer Lett
25654087The effect of CYP, GST, and SULT polymorphisms and their interaction with smoking on the risk of hepatocellular carcinoma. (2015)Boccia SBiomed Res Int
29721061The Interaction of Smoking with Gene Polymorphisms on Four Digestive Cancers: A Systematic Review and Meta-Analysis. (2018)Du LJ Cancer
16380991Fruit consumption reduces the effect of smoking on bladder cancer risk. The Belgian case control study on bladder cancer. (2006 May 15)Kellen EInt J Cancer
22946908Sulfation of buprenorphine, pentazocine, and naloxone by human cytosolic sulfotransferases. (2012 Jun 1)Kurogi KDrug Metab Lett
11804685Sulfotransferase (SULT) 1A1 polymorphism as a predisposition factor for lung cancer: a case-control analysis. (2002 Feb)Wang YLung Cancer