Gene: TAC1

6863
Hs.2563|NK2|NKNA|NPK|TAC2
tachykinin precursor 1
protein-coding
7q21.3
Ensembl:ENSG00000006128 MIM:162320 Vega:OTTHUMG00000154069 UniprotKB:P20366
NC_000007.14
PubMed
ND
1   
6.035e-1 (AD)  1.793e-1 (ND)   (Frontal_Cortex)
1.341e-3 (AD)  6.522e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GAD20.924
PCP4L10.904
GAD10.899
SLC32A10.878
CRHBP0.869
MYOZ30.861
SST0.859
BTBD110.855
KCNAB10.853
NRIP30.851

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CDA-0.577
CDC14A-0.526
MAGEA12-0.519
GPR4-0.517
TNFRSF10D-0.511
LATS2-0.505
OTOS-0.5
REST-0.499
RGL3-0.499
S100A12-0.495

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]"20736509
C0389831,3-dimethylthiourea"1,3-dimethylthiourea inhibits the reaction [Lipopolysaccharides results in increased expression of TAC1 mRNA]"12738685
C0602291-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]"20736509
C0602291-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]"18809416
C0602291-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [KNG1 protein inhibits the reaction [Potassium Chloride results in increased secretion of TAC1 protein]]"16696851
C499293(1'S, 2S)-4-amino-N-(1'-carbamoyl-2'-phenylethyl)-2-(4''-methyl-1''-naphthalenesulfonylamino)butanamide"(1'S, 2S)-4-amino-N-(1'-carbamoyl-2'-phenylethyl)-2-(4''-methyl-1''-naphthalenesulfonylamino)butanamide results in decreased secretion of TAC1 protein"16953190
C5528882-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide"2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [[Ovalbumin co-treated with Formaldehyde] results in increased expression of TAC1 protein]"23671638
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of TAC1 mRNA19933214
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of TAC1 mRNA"25510870
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of TAC1 mRNA"25614096
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl affects the expression of TAC1 mRNA"19114083
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of TAC1 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of TAC1 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of TAC1 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of TAC1 mRNA"25510870
C0269422,6-diisocyanatotoluene"[Toluene 2,4-Diisocyanate co-treated with 2,6-diisocyanatotoluene] results in increased expression of TAC1 mRNA"10673198
C0269422,6-diisocyanatotoluene"[Toluene 2,4-Diisocyanate co-treated with 2,6-diisocyanatotoluene] results in increased expression of TAC1 protein"10673198
C1099862-aminoethoxydiphenyl borate2-aminoethoxydiphenyl borate inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
C5387582-aminoethyl diphenylborinate2-aminoethyl diphenylborinate inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]16696851
C5387582-aminoethyl diphenylborinate2-aminoethyl diphenylborinate inhibits the reaction [Potassium Chloride results in increased secretion of TAC1 protein]16696851
C5387582-aminoethyl diphenylborinate2-aminoethyl diphenylborinate promotes the reaction [KNG1 protein inhibits the reaction [Potassium Chloride results in increased secretion of TAC1 protein]]16696851
C0303702-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone"2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone results in decreased expression of TAC1 mRNA"20206263
C0807553-(2-methoxybenzylamino)-2-phenylpiperidine3-(2-methoxybenzylamino)-2-phenylpiperidine inhibits the reaction [TAC1 protein results in increased expression of MMP12 mRNA]18441096
C0807553-(2-methoxybenzylamino)-2-phenylpiperidine3-(2-methoxybenzylamino)-2-phenylpiperidine inhibits the reaction [TAC1 protein results in increased expression of TACR1 mRNA]18441096
C0153923-nitropropionic acid3-nitropropionic acid results in decreased expression of TAC1 mRNA17672854
C0153923-nitropropionic acidCannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of TAC1 mRNA]17672854
C4861844,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol"4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol affects the expression of TAC1 mRNA"19627578
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [TAC1 protein modified form results in increased expression of ACTA2 protein]"28647476
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased secretion of TAC1 protein17684094
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C0716937,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one"7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one inhibits the reaction [sodium arsenite results in increased secretion of TAC1 protein]"17056641
C0716937,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one"7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one inhibits the reaction [TAC1 protein modified form results in increased expression of ACTA2 protein]"28647476
C0716937,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one"7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one results in decreased activity of TAC1 protein"8938667
C496492abrineabrine results in decreased expression of TAC1 mRNA22595364
D000082AcetaminophenAcetaminophen results in increased expression of TAC1 mRNA26690555
D000082AcetaminophenAcetaminophen results in increased expression of TAC1 protein16449370
D000082AcetaminophenAcetaminophen affects the expression of TAC1 mRNA17562736
D000082AcetaminophenAcetaminophen inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA]21811393
D000109AcetylcholineTAC1 protein affects the abundance of Acetylcholine11020227
D000109AcetylcholineUrethane affects the reaction [TAC1 protein affects the abundance of Acetylcholine]11020227
D000143AcidsAcids results in increased secretion of TAC1 protein16091555|2010027
D000143Acidscapsazepine inhibits the reaction [Acids results in increased secretion of TAC1 protein]16091555
D000171AcroleinAcrolein results in increased expression of TAC1 protein1696540
D020106AcrylamideAcrylamide results in decreased expression of TAC1 protein1647505
D000255Adenosine Triphosphate"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]"20736509
D000255Adenosine Triphosphate"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]"20736509
D000255Adenosine Triphosphate2-aminoethoxydiphenyl borate inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D000255Adenosine TriphosphateBenzbromarone inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D000255Adenosine Triphosphatecyclo(Gln-Trp-Phe-Gly-Leu-Met) inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D000255Adenosine TriphosphateIndomethacin inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D000255Adenosine TriphosphateStaurosporine inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D000255Adenosine TriphosphateTAC1 protein results in increased secretion of Adenosine Triphosphate20736509
D000255Adenosine TriphosphateThapsigargin inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D000255Adenosine Triphosphateverlukast inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D000255Adenosine TriphosphateW 7 inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D000255Adenosine TriphosphateAdenosine Triphosphate results in increased secretion of TAC1 protein16039053
D000255Adenosine TriphosphateIloprost promotes the reaction [Adenosine Triphosphate results in increased secretion of TAC1 protein]16039053
D016604Aflatoxin B1Aflatoxin B1 affects the expression of TAC1 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of TAC1 gene27153756
C412373AG 1879AG 1879 inhibits the reaction [IL1B protein results in increased activity of TAC1 protein]14622206
D000420AlbuterolAlbuterol promotes the reaction [Paraoxon results in increased secretion of TAC1 protein]17158603
C047638alfuzosinalfuzosin inhibits the reaction [Phenylephrine results in increased secretion of TAC1 protein]17240043
C004471allyl isothiocyanateallyl isothiocyanate results in increased secretion of TAC1 protein16725114
D000643Ammonium ChlorideAmmonium Chloride affects the expression of TAC1 mRNA16483693
D000657AmoxapineAmoxapine results in decreased expression of TAC1 protein8955926
D003913DextroamphetamineDextroamphetamine results in increased expression of TAC1 mRNA11566502|1255898
D003913DextroamphetamineDextroamphetamine results in increased expression of TAC1 mRNA11532335|1189708
D003913DextroamphetamineLY 306740 inhibits the reaction [Dextroamphetamine results in increased expression of TAC1 mRNA]11897087
D003913DextroamphetamineU 69593 inhibits the reaction [Dextroamphetamine results in increased expression of TAC1 mRNA]11532335
D000661AmphetamineAmphetamine results in increased expression of TAC1 mRNA15033416
D000661AmphetamineBaclofen inhibits the reaction [Amphetamine results in increased expression of TAC1 mRNA]15033416
D000781Anethole TrithioneAnethole Trithione results in increased expression of TAC1 protein11804400
D000809AngiotensinsAngiotensins results in increased expression of TAC1 mRNA21294877
D039741Antigens, Dermatophagoides"[Methoxychlor co-treated with Antigens, Dermatophagoides] affects the expression of TAC1 protein"21864637
D039741Antigens, Dermatophagoides"[Parathion co-treated with Antigens, Dermatophagoides] affects the expression of TAC1 protein"21864637
D001030ApaminApamin results in decreased activity of TAC1 protein11877319
D001058ApomorphineApomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA]17719177
C114556aprepitantaprepitant inhibits the reaction [TAC1 protein results in increased expression of MMP12 mRNA]18441096
C114556aprepitantaprepitant inhibits the reaction [TAC1 protein results in increased expression of TACR1 mRNA]18441096
C015001arsenitearsenite results in increased methylation of TAC1 promoter23974009
D001280AtrazineAtrazine results in decreased expression of TAC1 mRNA25929836
D001418BaclofenBaclofen inhibits the reaction [Amphetamine results in increased expression of TAC1 mRNA]15033416
C080985batimastatbatimastat inhibits the reaction [TAC1 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]15319441
C080985batimastatbatimastat inhibits the reaction [TAC1 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]15319441
C080985batimastatbatimastat inhibits the reaction [TAC1 protein results in increased secretion of TGFA protein]15319441
D001553BenzbromaroneBenzbromarone inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D001554Benzene[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in decreased expression of TAC122863854
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased methylation of TAC1 promoter28329817
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TAC1 mRNA20106945
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of TAC1 mRNA23735875
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TAC1 mRNA19770486|2373587
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of TAC1 mRNA21839799
D004958EstradiolEstradiol results in increased expression of TAC1 mRNA20106945
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C006780bisphenol Abisphenol A results in decreased expression of TAC1 mRNA25181051
D019274Botulinum Toxins, Type A"Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased secretion of TAC1 protein]"18184328
D019274Botulinum Toxins, Type A"Botulinum Toxins, Type A inhibits the reaction [Hydrochloric Acid results in increased secretion of TAC1 protein]"18184328
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TAC1 mRNA22079614
C048491butaprostbutaprost promotes the reaction [Kallidin results in increased secretion of TAC1 protein]16039053
D002084Butylated HydroxytolueneButylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]9748608
D002087ButyratesButyrates results in increased expression of TAC1 protein17187013
D002118CalciumTAC1 protein results in increased abundance of Calcium20736509
D002118Calciumpalonosetron inhibits the reaction [Serotonin promotes the reaction [TAC1 protein results in increased abundance of Calcium]]20724484
D002118CalciumSerotonin promotes the reaction [TAC1 protein results in increased abundance of Calcium]20724484
D002118CalciumTAC1 protein results in increased abundance of Calcium20724484
D002118CalciumCP 96345 inhibits the reaction [TAC1 protein alternative form results in increased abundance of Calcium]7513838
D002118CalciumTAC1 protein alternative form results in increased abundance of Calcium7513838
D002118CalciumTACR1 protein affects the reaction [TAC1 protein alternative form results in increased abundance of Calcium]7513838
D002185CannabidiolCannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of TAC1 mRNA]17672854
D002211CapsaicinCapsaicin results in decreased expression of TAC1 protein3106456|6194277
D002211Capsaicincapsazepine inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]7694442
D002211CapsaicinRuthenium Red inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]7694442
D002211CapsaicinCapsaicin results in decreased expression of TAC1 protein17884737
D002211CapsaicinCapsaicin results in decreased expression of TAC1 mRNA14987252
D002211CapsaicinCapsaicin results in decreased expression of TAC1 protein14987252
D002211CapsaicinCapsaicin results in increased secretion of TAC1 protein9973426
D002211CapsaicinCapsaicin affects the expression of TAC1 protein18344596
D002211Capsaicin[Capsaicin co-treated with CCK protein alternative form] results in increased expression of TAC1 protein10683199
D002211CapsaicinCapsaicin inhibits the reaction [sodium arsenite results in increased secretion of TAC1 protein]17056641
D002211CapsaicinCapsaicin results in decreased expression of TAC1 mRNA18441096
D002211CapsaicinCapsaicin results in increased expression of TAC1 mRNA21294877
D002211CapsaicinCapsaicin results in increased expression of TAC1 protein21294877
D002211CapsaicinCapsaicin results in increased secretion of TAC1 protein22062353
D002211CapsaicinCapsaicin results in increased secretion of TAC1 protein alternative form18845912
D002211CapsaicinSCN10A protein affects the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]18845912
D002211CapsaicinTAC1 protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]18203709
D002211Capsaicin"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]"18809416
D002211Capsaicin2-aminoethyl diphenylborinate inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]16696851
D002211CapsaicinAMN protein inhibits the reaction [Capsaicin results in increased expression of TAC1 protein]16938409
D002211Capsaicinbisindolylmaleimide I inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D002211CapsaicinCapsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of TAC1 mRNA]7473211
D002211CapsaicinCapsaicin inhibits the reaction [Potassium results in increased secretion of TAC1 protein modified form]2325850
D002211CapsaicinCapsaicin results in decreased expression of TAC1 mRNA8971780|9259450
D002211CapsaicinCapsaicin results in decreased expression of TAC1 protein13680092|1695941
D002211CapsaicinCapsaicin results in decreased secretion of TAC1 protein14521749
D002211CapsaicinCapsaicin results in increased expression of and results in increased secretion of TAC1 protein6205719
D002211CapsaicinCapsaicin results in increased expression of TAC1 mRNA16959413
D002211CapsaicinCapsaicin results in increased expression of TAC1 protein16938409|1757471
D002211CapsaicinCapsaicin results in increased secretion of TAC1 protein14499429|1575028
D002211CapsaicinCapsaicin results in increased secretion of TAC1 protein alternative form19112407
D002211CapsaicinCapsaicin results in increased secretion of TAC1 protein modified form2325850
D002211Capsaicincapsazepine inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]15750287|2219800
D002211Capsaicincapsazepine inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D002211Capsaicincochinchinenin inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]22198006
D002211CapsaicinColforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]15750287
D002211CapsaicinCP 96345 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D002211Capsaicindragon's blood inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]22198006
D002211CapsaicinFreund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]14499429
D002211Capsaicingabapentin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]14499429
D002211CapsaicinGAL protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]19112407
D002211CapsaicinGo 6976 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D002211CapsaicinGR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]18809416
D002211CapsaicinHU 211 inhibits the reaction [Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]15750287
D002211CapsaicinHU 211 inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]15750287
D002211CapsaicinIloprost promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]16039053
D002211CapsaicinIndomethacin inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D002211CapsaicinIndomethacin inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]16696851
D002211CapsaicinKNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]15750287
D002211CapsaicinKNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]16696851
D002211CapsaicinMorphine promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]15964684
D002211CapsaicinN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]15750287
D002211CapsaicinN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D002211CapsaicinNGF protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]17687396
D002211Capsaicin"Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]"14499429
D002211CapsaicinPregabalin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]14499429
D002211Capsaicin"Pregabalin inhibits the reaction [Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]"14499429
D002211Capsaicinpyrazolanthrone promotes the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D002211CapsaicinSB 203580 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D002211CapsaicinTAC1 protein results in decreased activity of Capsaicin14985054
D002211CapsaicinU 0126 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D002211CapsaicinCapsaicin results in increased secretion of TAC1 protein10766449
D002211CapsaicinCapsaicin results in increased expression of TAC1 mRNA21294877
D002211CapsaicinCapsaicin results in increased secretion of TAC1 protein19368813
C071423capsazepinecapsazepine inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]7694442
C071423capsazepinecapsazepine inhibits the reaction [Acids results in increased secretion of TAC1 protein]16091555
C071423capsazepinecapsazepine inhibits the reaction [[Ovalbumin co-treated with Formaldehyde] results in increased expression of TAC1 protein]23671638
C071423capsazepinecapsazepine inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]15750287|2219800
C071423capsazepinecapsazepine inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D002220CarbamazepineCarbamazepine affects the expression of TAC1 mRNA25979313
D002330CarmustineCarmustine results in decreased expression of TAC1 mRNA15980968
D002721omega-Chloroacetophenoneomega-Chloroacetophenone results in increased expression of TAC1 protein19458046
D004390ChlorpyrifosChlorpyrifos affects the expression of TAC1 mRNA20682304
D002772Cholera ToxinTAC1 protein alternative form inhibits the reaction [Cholera Toxin results in increased secretion of Water]11040190
D002772Cholera ToxinTAC1 protein inhibits the reaction [Cholera Toxin results in increased secretion of Water]11040190
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of TAC1 mRNA28472532
D002997ClomipramineClomipramine results in decreased expression of TAC1 protein8955926
D003024ClozapineClozapine results in decreased expression of TAC1 mRNA17266109
D003024ClozapineClozapine results in decreased expression of TAC1 mRNA10974607
D003042CocaineCocaine affects the expression of TAC1 mRNA11072100
D003042CocaineCocaine results in increased expression of TAC1 mRNA16395306|1789822
C475447cochinchinenincochinchinenin inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]22198006
C475447cochinchinenincochinchinenin inhibits the reaction [KNG1 results in increased secretion of TAC1 protein]22198006
D005576ColforsinColforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]15750287
D005576ColforsinHU 211 inhibits the reaction [Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]15750287
D003300CopperCopper binds to and results in increased oxidation of TAC1 protein modified form20121248|2043535
D003300CopperCopper results in increased oxidation of TAC1 protein23314592
C066892CP 96345CP 96345 results in decreased activity of TAC1 protein10490918
C066892CP 96345CP 96345 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C066892CP 96345CP 96345 inhibits the reaction [TAC1 protein affects the localization of TACR1 protein]7524481
C066892CP 96345CP 96345 inhibits the reaction [TAC1 protein alternative form results in increased abundance of Calcium]7513838
D004205Cromolyn SodiumCromolyn Sodium inhibits the reaction [Paclitaxel results in increased expression of TAC1 protein]15033348
D003471CuprizoneCuprizone results in decreased expression of TAC1 mRNA27523638
D003471CuprizoneCuprizone results in increased expression of TAC1 mRNA26577399
D0187506-Cyano-7-nitroquinoxaline-2,3-dione"6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [L 703606 results in increased activity of TAC1 protein]"14985054
C073361cyclo(Gln-Trp-Phe-Gly-Leu-Met)cyclo(Gln-Trp-Phe-Gly-Leu-Met) inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
C073361cyclo(Gln-Trp-Phe-Gly-Leu-Met)cyclo(Gln-Trp-Phe-Gly-Leu-Met) inhibits the reaction [L 703606 results in increased activity of TAC1 protein]14985054
D003513CycloheximideCycloheximide inhibits the reaction [KNG1 protein results in increased secretion of TAC1 protein]16696851
D003520CyclophosphamideCyclophosphamide results in increased expression of TAC1 protein22842586
D003520Cyclophosphamide"Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased secretion of TAC1 protein]"18184328
D003520CyclophosphamideCyclophosphamide affects the expression of TAC1 mRNA18563302
D003520CyclophosphamideCyclophosphamide results in increased expression of TAC1 protein11312054
D003520CyclophosphamideCyclophosphamide results in increased secretion of TAC1 protein18184328
D016572CyclosporineCyclosporine results in increased expression of TAC1 mRNA20106945
C017160cypermethrincypermethrin inhibits the reaction [Dopamine affects the activity of TAC1 protein]11487621
C017160cypermethrincypermethrin inhibits the reaction [Serotonin affects the activity of TAC1 protein]11487621
D003561CytarabineCytarabine results in increased expression of TAC1 mRNA21198554
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of TAC1 mRNA23914054
D015230Prostaglandin D2Prostaglandin D2 promotes the reaction [Kallidin results in increased secretion of TAC1 protein]16039053
D013759Dronabinol[Dronabinol co-treated with Ethanol] results in increased expression of TAC1 mRNA17618662
D013759DronabinolDronabinol results in decreased expression of TAC1 mRNA17578508
D013759DronabinolDronabinol results in increased expression of TAC1 mRNA17618662|7515821
D003891DesipramineDesipramine results in decreased expression of TAC1 protein8955926
D003907DexamethasoneDexamethasone results in increased expression of TAC1 protein22842586
C492519diarylpropionitrilediarylpropionitrile results in increased expression of TAC1 mRNA19627578
D003975DiazepamTAC1 protein modified form results in decreased susceptibility to Diazepam20600432
D003976DiazinonDiazinon results in increased expression of TAC1 mRNA20682304
D002945CisplatinCisplatin results in increased susceptibility to TAC1 protein20724484
D002945Cisplatinpalonosetron inhibits the reaction [Cisplatin results in increased susceptibility to TAC1 protein]20724484
D004026DieldrinDieldrin results in increased expression of TAC1 mRNA20682304
D004041Dietary FatsDietary Fats results in decreased expression of TAC1 mRNA21852083
D016291Dizocilpine MaleateDizocilpine Maleate inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of TAC1 protein modified form]11074153
D004280DobutamineDobutamine promotes the reaction [TAC1 protein binds to and results in increased activity of TACR1 protein]8994422
D004298Dopaminecypermethrin inhibits the reaction [Dopamine affects the activity of TAC1 protein]11487621
C525191dragon's blooddragon's blood inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]22198006
C525191dragon's blooddragon's blood inhibits the reaction [KNG1 results in increased secretion of TAC1 protein]22198006
C525191dragon's blooddragon's blood results in decreased expression of TAC1 mRNA22198006
D004656EnalaprilEnalapril inhibits the reaction [ACE protein results in increased degradation of TAC1 protein modified form]2008223
C118739entinostatentinostat results in decreased expression of TAC1 mRNA27188386
C118739entinostatentinostat results in increased expression of TAC1 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C010452estradiol-17 beta-benzoateestradiol-17 beta-benzoate affects the expression of TAC1 mRNA19627578
D000431Ethanol[Dronabinol co-treated with Ethanol] results in increased expression of TAC1 mRNA17618662
D000431EthanolEthanol results in increased expression of TAC1 mRNA17618662
D005054EugenolEugenol affects the susceptibility to TAC1 protein21547684
C078949FK 888FK 888 affects the activity of TAC1 protein7889271
D005476FluphenazineFluphenazine results in decreased expression of TAC1 mRNA15845098
D005557Formaldehyde"2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [[Ovalbumin co-treated with Formaldehyde] results in increased expression of TAC1 protein]"23671638
D005557Formaldehydecapsazepine inhibits the reaction [[Ovalbumin co-treated with Formaldehyde] results in increased expression of TAC1 protein]23671638
D005557Formaldehyde[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in decreased expression of TAC122863854
D005557Formaldehyde[Ovalbumin co-treated with Formaldehyde] results in increased expression of TAC1 protein23671638
D005557FormaldehydeFormaldehyde results in increased expression of TAC1 protein18197882
D005620Freund's AdjuvantFreund's Adjuvant results in increased secretion of TAC1 protein15131310
D005620Freund's AdjuvantCapsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of TAC1 mRNA]7473211
D005620Freund's AdjuvantFreund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]14499429
D005620Freund's AdjuvantFreund's Adjuvant results in increased expression of TAC1 mRNA7473211
D005620Freund's Adjuvantgabapentin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]14499429
D005620Freund's AdjuvantPregabalin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]14499429
C039281furanfuran results in increased expression of TAC1 mRNA27387713
C040029gabapentingabapentin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]14499429
D019833GenisteinGenistein inhibits the reaction [IL1B protein results in increased activity of TAC1 protein]14622206
D019833GenisteinGenistein inhibits the reaction [IL1B protein results in increased expression of TAC1 mRNA]14622206
C081021Go 6976Go 6976 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C068032GR 73632"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]"18809416
C068032GR 73632bisindolylmaleimide I inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C068032GR 73632capsazepine inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C068032GR 73632CP 96345 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C068032GR 73632Go 6976 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C068032GR 73632GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]18809416
C068032GR 73632Indomethacin inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C068032GR 73632N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C068032GR 73632pyrazolanthrone promotes the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C068032GR 73632SB 203580 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C068032GR 73632U 0126 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C412815GW 4064GW 4064 results in increased expression of TAC1 mRNA26655953
D006220HaloperidolHaloperidol results in increased expression of TAC1 mRNA10974607
C020754herbimycinherbimycin inhibits the reaction [IL1B protein results in increased activity of TAC1 protein]14622206
C020754herbimycinherbimycin inhibits the reaction [IL1B protein results in increased expression of TAC1 mRNA]14622206
D006632HistamineNedocromil inhibits the reaction [TAC1 protein results in increased secretion of Histamine]1707400
D006632HistamineTAC1 protein results in increased secretion of Histamine1707400|9291295
D006632HistamineTheophylline inhibits the reaction [TAC1 protein results in increased secretion of Histamine]1707400
D006632HistamineDinoprostone promotes the reaction [Histamine promotes the reaction [Serotonin promotes the reaction [KNG1 protein results in increased secretion of TAC1 protein]]]11166334
D006632HistamineHistamine promotes the reaction [Serotonin promotes the reaction [KNG1 protein results in increased secretion of TAC1 protein]]11166334
D006632HistamineITGA2 protein results in increased susceptibility to [KNG1 protein modified form co-treated with TAC1 protein modified form co-treated with Serotonin co-treated with Dinoprostone co-treated with Histamine]18234883
D012701Serotonincypermethrin inhibits the reaction [Serotonin affects the activity of TAC1 protein]11487621
D012701SerotoninDinoprostone promotes the reaction [Histamine promotes the reaction [Serotonin promotes the reaction [KNG1 protein results in increased secretion of TAC1 protein]]]11166334
D012701SerotoninHistamine promotes the reaction [Serotonin promotes the reaction [KNG1 protein results in increased secretion of TAC1 protein]]11166334
D012701SerotoninITGA2 protein results in increased susceptibility to [KNG1 protein modified form co-treated with TAC1 protein modified form co-treated with Serotonin co-treated with Dinoprostone co-treated with Histamine]18234883
D012701SerotoninSerotonin promotes the reaction [KNG1 protein results in increased secretion of TAC1 protein]11166334
D012701Serotoninpalonosetron inhibits the reaction [Serotonin promotes the reaction [TAC1 protein results in increased abundance of Calcium]]20724484
D012701SerotoninSerotonin promotes the reaction [TAC1 protein results in increased abundance of Calcium]20724484
C062018HU 211HU 211 inhibits the reaction [Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]15750287
C062018HU 211HU 211 inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]15750287
D006851Hydrochloric AcidHydrochloric Acid results in decreased expression of TAC1 protein19957777
D006851Hydrochloric AcidHydrochloric Acid results in increased expression of and results in increased secretion of TAC1 protein20616304
D006851Hydrochloric Acid"Botulinum Toxins, Type A inhibits the reaction [Hydrochloric Acid results in increased secretion of TAC1 protein]"18184328
D006851Hydrochloric AcidHydrochloric Acid results in increased secretion of TAC1 protein18184328
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of TAC1 mRNA26339600
D006861Hydrogen PeroxideTAC1 protein affects the metabolism of Hydrogen Peroxide20616304
D01979615-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid"TAC1 protein results in decreased activity of 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid"18463244
D01979615-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid"TAC1 protein results in decreased activity of 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid"18463244
C065679icatibanticatibant inhibits the reaction [KNG1 protein inhibits the reaction [Potassium Chloride results in increased secretion of TAC1 protein]]16696851
C065679icatibanticatibant inhibits the reaction [KNG1 results in increased secretion of TAC1 protein]22198006
D016285IloprostIloprost promotes the reaction [Adenosine Triphosphate results in increased secretion of TAC1 protein]16039053
D016285IloprostIloprost promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]16039053
D016285IloprostIloprost promotes the reaction [Kallidin results in increased secretion of TAC1 protein]16039053
D016285IloprostIloprost promotes the reaction [Potassium Chloride results in increased secretion of TAC1 protein]16039053
D007099ImipramineImipramine results in decreased expression of TAC1 protein8955926
C052241imirestatimirestat inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]1374869
D007213IndomethacinIndomethacin inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D007213IndomethacinIndomethacin inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D007213IndomethacinIndomethacin inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]16696851
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TAC1 mRNA25613284
D007545IsoproterenolTAC1 protein affects the susceptibility to Isoproterenol11270094
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of TAC1 protein17574719
C098607JP8 aviation fuelSR 140333 inhibits the reaction [JP8 aviation fuel results in increased expression of TAC1 protein]17574719
C094211JTP 4819JTP 4819 results in decreased degradation of TAC1 protein modified form7562510
D007608Kainic AcidKainic Acid results in decreased expression of TAC1 protein6205719
D007609Kallidinbutaprost promotes the reaction [Kallidin results in increased secretion of TAC1 protein]16039053
D007609KallidinDinoprostone promotes the reaction [Kallidin results in increased secretion of TAC1 protein]16039053
D007609KallidinIloprost promotes the reaction [Kallidin results in increased secretion of TAC1 protein]16039053
D007609KallidinKallidin results in increased secretion of TAC1 protein16039053
D007609KallidinMisoprostol promotes the reaction [Kallidin results in increased secretion of TAC1 protein]16039053
D007609KallidinProstaglandin D2 promotes the reaction [Kallidin results in increased secretion of TAC1 protein]16039053
C076851L 703606"6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [L 703606 results in increased activity of TAC1 protein]"14985054
C076851L 703606cyclo(Gln-Trp-Phe-Gly-Leu-Met) inhibits the reaction [L 703606 results in increased activity of TAC1 protein]14985054
C076851L 703606L 703606 results in increased activity of TAC1 protein14985054
D007854LeadLead affects the splicing of TAC1 mRNA28903495
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of TAC1 mRNA"22384199
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TAC1 mRNA21294877
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TAC1 protein17291600|2129487
D008070Lipopolysaccharidesresiniferatoxin inhibits the reaction [Lipopolysaccharides results in increased expression of TAC1 protein]17291600
D008070LipopolysaccharidesTAC1 results in increased susceptibility to Lipopolysaccharides21294877
D008070Lipopolysaccharides"1,3-dimethylthiourea inhibits the reaction [Lipopolysaccharides results in increased expression of TAC1 mRNA]"12738685
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TAC1 mRNA12738685
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TAC1 protein21570423
D008094LithiumDizocilpine Maleate inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of TAC1 protein modified form]11074153
D008094Lithium[Pilocarpine co-treated with Lithium] results in increased expression of TAC1 mRNA11074153
D008094Lithium[Pilocarpine co-treated with Lithium] results in increased expression of TAC1 protein modified form11074153
C102280LY 306740LY 306740 inhibits the reaction [Dextroamphetamine results in increased expression of TAC1 mRNA]11897087
D008610MentholMenthol results in decreased susceptibility to TAC1 protein alternative form9504389
C042720mercuric bromidemercuric bromide results in increased expression of TAC1 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
D008627Mercuric ChlorideMercuric Chloride promotes the reaction [TAC1 protein results in increased secretion of IL6 protein]20222982
D008628MercuryMercury results in increased expression of TAC1 mRNA16823088
D008694MethamphetamineMethamphetamine results in increased expression of TAC1 mRNA15644446
D008731Methoxychlor"[Methoxychlor co-treated with Antigens, Dermatophagoides] affects the expression of TAC1 protein"21864637
C005223methyleugenolmethyleugenol inhibits the reaction [TAC1 protein results in increased expression of HDC mRNA]9125128
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of TAC1 mRNA23458150
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of TAC1 mRNA28001369
D008803MianserinMianserin results in decreased expression of TAC1 protein8955926
D016595MisoprostolMisoprostol promotes the reaction [Kallidin results in increased secretion of TAC1 protein]16039053
D009020MorphineMorphine results in increased expression of TAC1 mRNA21178816
D009020MorphineMorphine promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]15964684
D009020MorphineMorphine results in increased expression of TAC1 protein11976266|1596468
D009020MorphineNaloxone inhibits the reaction [Morphine results in increased expression of TAC1 protein]11976266
D009151Mustard GasMustard Gas results in increased expression of TAC1 protein15388249
D009151Mustard Gasolvanil inhibits the reaction [Mustard Gas results in increased expression of TAC1 protein]15388249
D015544Inositol 1,4,5-Trisphosphate"TAC1 protein results in increased abundance of Inositol 1,4,5-Trisphosphate"20736509
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]15750287
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C078131N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamideN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide results in decreased degradation of and results in increased expression of and results in increased secretion of TAC1 protein23894327
C028473N-acetyl-4-benzoquinoneimineN-acetyl-4-benzoquinoneimine results in increased secretion of TAC1 protein20720158
D009270NaloxoneNaloxone inhibits the reaction [Morphine results in increased expression of TAC1 protein]11976266
C005274naringinnaringin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TAC1 protein]24085318
C007548n-dodecanen-dodecane results in increased expression of TAC1 protein modified form19152832
D017835NedocromilNedocromil inhibits the reaction [TAC1 protein results in increased secretion of Histamine]1707400
D064729Neurokinin-1 Receptor AntagonistsNeurokinin-1 Receptor Antagonists inhibits the reaction [TAC1 protein modified form results in increased expression of TGFB1 protein]28647476
D064729Neurokinin-1 Receptor AntagonistsNeurokinin-1 Receptor Antagonists inhibits the reaction [TAC1 protein modified form results in increased phosphorylation of SMAD3 protein]28647476
D064729Neurokinin-1 Receptor AntagonistsNeurokinin-1 Receptor Antagonists inhibits the reaction [TAC1 protein modified form results in increased expression of ACTA2 protein]28647476
D064729Neurokinin-1 Receptor AntagonistsNeurokinin-1 Receptor Antagonists inhibits the reaction [TAC1 protein modified form results in increased expression of TGFB1 protein]28647476
D064729Neurokinin-1 Receptor AntagonistsNeurokinin-1 Receptor Antagonists inhibits the reaction [TAC1 protein modified form results in increased phosphorylation of SMAD3 protein]28647476
C028007nickel monoxidenickel monoxide results in decreased expression of TAC1 mRNA19167457
C012655nimesulidenimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA]21811393
C012655nimesulidenimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of TAC1 protein]21811393
C012655nimesulidenimesulide inhibits the reaction [NGF protein results in increased secretion of TAC1 protein]21811393
C012655nimesulidenimesulide inhibits the reaction [NGF results in increased expression of TAC1 mRNA]21811393
C012655nimesulidenimesulide results in decreased expression of TAC1 mRNA21811393
D009569Nitric OxideTAC1 protein results in increased abundance of Nitric Oxide12672649
D009585Nitrogen DioxideNitrogen Dioxide results in decreased expression of TAC1 protein8880101
D005996NitroglycerinNitroglycerin affects the expression of TAC1 protein18197882
D016567NizatidineNizatidine results in increased expression of TAC1 protein12495560
C017573nonanenonane results in increased expression of TAC1 protein modified form19152832
D004963EstrenesEstrenes results in increased expression of TAC1 mRNA19627578
D016627OxidopamineOxidopamine results in decreased expression of TAC1 mRNA15610165|1868738
D016627OxidopamineOxidopamine results in increased expression of TAC1 mRNA15303306
C054256olvanilolvanil inhibits the reaction [Mustard Gas results in increased expression of TAC1 protein]15388249
D020866omega-Conotoxin GVIAomega-Conotoxin GVIA inhibits the reaction [Potassium results in increased secretion of TAC1 protein modified form]2325850
D010047Ovalbumin"2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [[Ovalbumin co-treated with Formaldehyde] results in increased expression of TAC1 protein]"23671638
D010047Ovalbumincapsazepine inhibits the reaction [[Ovalbumin co-treated with Formaldehyde] results in increased expression of TAC1 protein]23671638
D010047Ovalbumin[Ovalbumin co-treated with Formaldehyde] results in increased expression of TAC1 protein23671638
C030110oxaliplatinoxaliplatin results in increased expression of TAC1 protein17418472
C029341oxophenylarsineoxophenylarsine inhibits the reaction [TAC1 protein affects the localization of TACR1 protein]7524481
D010100Oxygen[TAC1 protein co-treated with phosphoramidon] results in increased uptake of Oxygen9808699
D010126OzoneOzone results in increased expression of TAC1 protein16777450
D010126OzoneOzone results in decreased expression of TAC1 protein9310018
D017239PaclitaxelCromolyn Sodium inhibits the reaction [Paclitaxel results in increased expression of TAC1 protein]15033348
D017239PaclitaxelPaclitaxel results in increased expression of TAC1 protein15033348
D017239PaclitaxelPaclitaxel results in increased secretion of TAC1 protein alternative form21233199
D017239Paclitaxelpemirolast inhibits the reaction [Paclitaxel results in increased expression of TAC1 protein]15033348
D017239Paclitaxelpemirolast inhibits the reaction [Paclitaxel results in increased secretion of TAC1 protein alternative form]21233199
C083418palonosetronpalonosetron inhibits the reaction [Cisplatin results in increased susceptibility to TAC1 protein]20724484
C083418palonosetronpalonosetron inhibits the reaction [Serotonin promotes the reaction [TAC1 protein results in increased abundance of Calcium]]20724484
C496932panobinostatpanobinostat results in increased expression of TAC1 mRNA26272509
D010261ParaoxonAlbuterol promotes the reaction [Paraoxon results in increased secretion of TAC1 protein]17158603
D010261ParaoxonParaoxon results in increased secretion of TAC1 protein17158603
D010278Parathion"[Parathion co-treated with Antigens, Dermatophagoides] affects the expression of TAC1 protein"21864637
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of TAC1 mRNA"25510870
C055139pemirolastpemirolast inhibits the reaction [Paclitaxel results in increased expression of TAC1 protein]15033348
C055139pemirolastpemirolast inhibits the reaction [Paclitaxel results in increased secretion of TAC1 protein alternative form]21233199
C055139pemirolastpemirolast results in decreased secretion of TAC1 protein21539837
C055139pemirolastpemirolast results in decreased secretion of TAC1 protein alternative form21233199
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of TAC1 mRNA26705709
D015232DinoprostoneDinoprostone promotes the reaction [Histamine promotes the reaction [Serotonin promotes the reaction [KNG1 protein results in increased secretion of TAC1 protein]]]11166334
D015232DinoprostoneDinoprostone promotes the reaction [Kallidin results in increased secretion of TAC1 protein]16039053
D015232DinoprostoneDinoprostone promotes the reaction [KNG1 protein results in increased secretion of TAC1 protein]11166334
D015232DinoprostoneITGA2 protein results in increased susceptibility to [KNG1 protein modified form co-treated with TAC1 protein modified form co-treated with Serotonin co-treated with Dinoprostone co-treated with Histamine]18234883
D010622PhencyclidinePhencyclidine results in decreased expression of TAC1 mRNA17266109
D010656Phenylephrinealfuzosin inhibits the reaction [Phenylephrine results in increased secretion of TAC1 protein]17240043
D010656PhenylephrinePhenylephrine results in increased secretion of TAC1 protein17240043
D010656PhenylephrineTAC1 protein affects the susceptibility to Phenylephrine11270094
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of TAC1 mRNA26272509
C008876phorbol-12,13-didecanoate"phorbol-12,13-didecanoate results in increased secretion of TAC1 protein alternative form"19075100
C008876phorbol-12,13-didecanoate"Sodium Chloride, Dietary promotes the reaction [phorbol-12,13-didecanoate results in increased secretion of TAC1 protein alternative form]"19075100
D015240Phorbol 12,13-Dibutyrate"Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]"14499429
D015240Phorbol 12,13-Dibutyrate"Pregabalin inhibits the reaction [Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]"14499429
C008890phosphoramidon[TAC1 protein co-treated with phosphoramidon] results in increased uptake of Oxygen9808699
D010862PilocarpineDizocilpine Maleate inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of TAC1 protein modified form]11074153
D010862Pilocarpine[Pilocarpine co-treated with Lithium] results in increased expression of TAC1 mRNA11074153
D010862Pilocarpine[Pilocarpine co-treated with Lithium] results in increased expression of TAC1 protein modified form11074153
C008922piperinepiperine results in decreased expression of TAC1 protein6205719
C006253pirinixic acidpirinixic acid results in increased expression of TAC1 mRNA20813756
D011188PotassiumCapsaicin inhibits the reaction [Potassium results in increased secretion of TAC1 protein modified form]2325850
D011188Potassiumomega-Conotoxin GVIA inhibits the reaction [Potassium results in increased secretion of TAC1 protein modified form]2325850
D011188PotassiumPotassium results in increased secretion of TAC1 protein modified form2325850
D011189Potassium ChloridePotassium Chloride results in increased expression of TAC1 mRNA21294877
D011189Potassium ChloridePotassium Chloride results in increased secretion of TAC1 protein alternative form18845912
D011189Potassium ChlorideSCN10A protein affects the reaction [Potassium Chloride results in increased secretion of TAC1 protein alternative form]18845912
D011189Potassium Chloride"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [KNG1 protein inhibits the reaction [Potassium Chloride results in increased secretion of TAC1 protein]]"16696851
D011189Potassium Chloride2-aminoethyl diphenylborinate inhibits the reaction [Potassium Chloride results in increased secretion of TAC1 protein]16696851
D011189Potassium Chloride2-aminoethyl diphenylborinate promotes the reaction [KNG1 protein inhibits the reaction [Potassium Chloride results in increased secretion of TAC1 protein]]16696851
D011189Potassium ChlorideAcetaminophen inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA]21811393
D011189Potassium Chlorideicatibant inhibits the reaction [KNG1 protein inhibits the reaction [Potassium Chloride results in increased secretion of TAC1 protein]]16696851
D011189Potassium ChlorideIloprost promotes the reaction [Potassium Chloride results in increased secretion of TAC1 protein]16039053
D011189Potassium Chloride[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA21811393
D011189Potassium Chloride[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of TAC1 protein21811393
D011189Potassium ChlorideKNG1 protein inhibits the reaction [Potassium Chloride results in increased secretion of TAC1 protein]16696851
D011189Potassium Chloridenimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA]21811393
D011189Potassium Chloridenimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of TAC1 protein]21811393
D011189Potassium ChloridePotassium Chloride results in increased secretion of TAC1 protein16039053|1669685
D011192Potassium DichromatePotassium Dichromate results in decreased expression of TAC1 mRNA23608068
D000069583PregabalinPregabalin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]14499429
D000069583Pregabalin"Pregabalin inhibits the reaction [Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]"14499429
D011374ProgesteroneSR 140333 inhibits the reaction [TAC1 protein results in decreased metabolism of Progesterone]15951421
D011374ProgesteroneTAC1 protein results in decreased metabolism of Progesterone15951421
D011441PropylthiouracilPropylthiouracil results in increased expression of TAC1 mRNA24780913
C432165pyrazolanthronepyrazolanthrone promotes the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C502851quinocetonequinocetone results in decreased expression of TAC1 mRNA27046791
D019257Quinpirole"[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine co-treated with Quinpirole] results in increased expression of TAC1 mRNA"9751140
D011899RanitidineRanitidine results in increased expression of TAC1 protein12495560
D012110Reserpine"[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine co-treated with Quinpirole] results in increased expression of TAC1 mRNA"9751140
D012110Reserpine"[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine] results in increased expression of TAC1 mRNA"9751140
D012110ReserpineApomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA]17719177
D012110ReserpineReserpine results in increased expression of TAC1 mRNA17719177
C024353resiniferatoxinRuthenium Red inhibits the reaction [resiniferatoxin results in increased secretion of TAC1 protein]7694442
C024353resiniferatoxinresiniferatoxin inhibits the reaction [Lipopolysaccharides results in increased expression of TAC1 protein]17291600
C024353resiniferatoxinresiniferatoxin results in decreased expression of TAC1 protein18219259
C116926rofecoxibrofecoxib results in increased expression of TAC1 protein16449370
D012430Ruthenium RedRuthenium Red inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]7694442
D012430Ruthenium RedRuthenium Red inhibits the reaction [resiniferatoxin results in increased secretion of TAC1 protein]7694442
C093642SB 203580SB 203580 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
D012601Scopolamine HydrobromideTAC1 protein modified form results in decreased susceptibility to Scopolamine Hydrobromide20600432
C009257sidnocarbsidnocarb results in increased expression of TAC1 mRNA12105094
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of TAC1 mRNA23806026
D012834SilverSilver results in increased expression of TAC1 mRNA26551752
C017947sodium arsenite"7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one inhibits the reaction [sodium arsenite results in increased secretion of TAC1 protein]"17056641
C017947sodium arseniteCapsaicin inhibits the reaction [sodium arsenite results in increased secretion of TAC1 protein]17056641
C017947sodium arsenitesodium arsenite results in increased expression of and results in increased secretion of TAC1 protein17056641
D017673Sodium Chloride, Dietary"Sodium Chloride, Dietary promotes the reaction [phorbol-12,13-didecanoate results in increased secretion of TAC1 protein alternative form]"19075100
D012999SomanSoman results in increased expression of TAC1 mRNA19281266
C026411sorbinilsorbinil inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]9748608
C065446spantide IIspantide II binds to and results in decreased activity of TAC1 protein15265675
C085215SR 140333SR 140333 results in decreased activity of TAC1 protein14561836
C085215SR 140333SR 140333 inhibits the reaction [JP8 aviation fuel results in increased expression of TAC1 protein]17574719
C085215SR 140333SR 140333 inhibits the reaction [TAC1 protein results in decreased metabolism of Progesterone]15951421
C085215SR 140333SR 140333 inhibits the reaction [Xylenes results in increased expression of TAC1 protein]17574719
C073839SR 48968SR 48968 results in decreased activity of TAC1 protein7889271
D019311StaurosporineStaurosporine inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
C049985staurosporine aglycone"staurosporine aglycone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of TAC1 protein]"14672914
D013311StreptozocinButylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]9748608
D013311Streptozocinimirestat inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]1374869
D013311Streptozocinsorbinil inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]9748608
D013311StreptozocinStreptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of TAC1 protein modified form]20832942
D013311StreptozocinStreptozocin results in decreased expression of TAC1 protein1374869
D013311StreptozocinStreptozocin results in decreased secretion of TAC1 protein modified form20832942
D013311StreptozocinStreptozocin results in increased expression of TAC1 mRNA9748608
C062618substance P, Sar(9)-Met(O2)(11)-"substance P, Sar(9)-Met(O2)(11)- results in increased expression of TAC1 mRNA"21294877
D013395SucroseSucrose inhibits the reaction [TAC1 protein affects the localization of TACR1 protein]7524481
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TAC1 mRNA20106945
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TAC1 mRNA17586704|1993321
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TAC1 mRNA25613284
D0156472,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine"[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine co-treated with Quinpirole] results in increased expression of TAC1 mRNA"9751140
D0156472,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine"[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine] results in increased expression of TAC1 mRNA"9751140
D019284ThapsigarginThapsigargin inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D013806TheophyllineTheophylline inhibits the reaction [TAC1 protein results in increased secretion of Histamine]1707400
D014028Tobacco Smoke Pollutionnaringin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TAC1 protein]24085318
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of TAC1 protein24085318
D014050Toluene[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in decreased expression of TAC122863854
D014051Toluene 2,4-Diisocyanate"NGF protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of TAC1 protein]"14672914
D014051Toluene 2,4-Diisocyanate"staurosporine aglycone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of TAC1 protein]"14672914
D014051Toluene 2,4-Diisocyanate"[Toluene 2,4-Diisocyanate co-treated with 2,6-diisocyanatotoluene] results in increased expression of TAC1 mRNA"10673198
D014051Toluene 2,4-Diisocyanate"[Toluene 2,4-Diisocyanate co-treated with 2,6-diisocyanatotoluene] results in increased expression of TAC1 protein"10673198
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of TAC1 protein"14672914
D014118Toxins, Biological"Toxins, Biological affects the expression of TAC1 mRNA"19682533
C032910triadimefontriadimefon results in increased expression of TAC1 mRNA26705709
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of TAC1 mRNA26272509
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of TAC1 mRNA17982090
C001899triptolidetriptolide inhibits the reaction [TAC1 protein results in increased expression of CXCL8 protein]20348278
D014403TubocurarineTubocurarine affects the activity of TAC1 protein11877319
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [TAC1 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]15319441
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [TAC1 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]15319441
C113580U 0126U 0126 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]18809416
C113580U 0126U 0126 inhibits the reaction [KNG1 protein results in increased secretion of TAC1 protein]16696851
C045444U 69593U 69593 inhibits the reaction [Dextroamphetamine results in increased expression of TAC1 mRNA]11532335
D014520UrethaneUrethane affects the reaction [TAC1 protein affects the abundance of Acetylcholine]11020227
D014635Valproic AcidValproic Acid affects the expression of TAC1 mRNA25979313
D014635Valproic AcidValproic Acid inhibits the reaction [TAC1 protein results in increased expression of IL6 mRNA]12807426
D014635Valproic AcidValproic Acid inhibits the reaction [TAC1 protein results in increased secretion of IL6 protein]12807426
D014635Valproic AcidValproic Acid results in decreased expression of TAC1 mRNA23179753|2718838
D014635Valproic AcidValproic Acid results in increased expression of TAC1 mRNA24383497|2627250
D014635Valproic AcidValproic Acid inhibits the reaction [TAC1 protein results in increased expression of IL6 mRNA]12807426
D014635Valproic AcidValproic Acid inhibits the reaction [TAC1 protein results in increased phosphorylation of and results in increased activity of PRKCE protein]12807426
D014635Valproic AcidValproic Acid inhibits the reaction [TAC1 protein results in increased secretion of IL6 protein]12807426
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of TAC1 mRNA15916011
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of TAC1 protein13680092|1591601
C059141verlukastverlukast inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAC1 mRNA"27188386
C111237vorinostatvorinostat results in increased expression of TAC1 mRNA26272509
C017967W 7W 7 inhibits the reaction [TAC1 protein results in increased secretion of Adenosine Triphosphate]20736509
D014867WaterTAC1 protein alternative form inhibits the reaction [Cholera Toxin results in increased secretion of Water]11040190
D014867WaterTAC1 protein inhibits the reaction [Cholera Toxin results in increased secretion of Water]11040190
D014992Xylenes[Formaldehyde co-treated with Benzene co-treated with Toluene co-treated with Xylenes] results in decreased expression of TAC122863854
D014992XylenesSR 140333 inhibits the reaction [Xylenes results in increased expression of TAC1 protein]17574719
D014992XylenesXylenes results in increased expression of TAC1 protein17574719
D015054ZymosanZymosan results in increased secretion of TAC1 protein15131310

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005102signaling receptor binding-IBA21873635  
GO:0031835substance P receptor binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0002675positive regulation of acute inflammatory response-IEA-  
GO:0006954inflammatory response-IBA21873635  
GO:0007186G-protein coupled receptor signaling pathway-TAS-  
GO:0007204positive regulation of cytosolic calcium ion concentration-IBA21873635  
GO:0007204positive regulation of cytosolic calcium ion concentration-IDA8957234  
GO:0007217tachykinin receptor signaling pathway-IBA21873635  
GO:0007218neuropeptide signaling pathway-IEA-  
GO:0007267cell-cell signaling-TAS1708336  
GO:0007268chemical synaptic transmission-IEA-  
GO:0007320insemination-TAS1708336  
GO:0007616long-term memory-IEA-  
GO:0008217regulation of blood pressure-IEA-  
GO:0008306associative learning-IEA-  
GO:0009582detection of abiotic stimulus-TAS9482938  
GO:0009725response to hormone-IEA-  
GO:0010459negative regulation of heart rate-IEA-  
GO:0010634positive regulation of epithelial cell migration-IEA-  
GO:0019233sensory perception of pain-IEA-  
GO:0032224positive regulation of synaptic transmission, cholinergic-IEA-  
GO:0032230positive regulation of synaptic transmission, GABAergic-IEA-  
GO:0032496response to lipopolysaccharide-IEA-  
GO:0035815positive regulation of renal sodium excretion-IEA-  
GO:0043278response to morphine-IEA-  
GO:0045760positive regulation of action potential-IEA-  
GO:0045778positive regulation of ossification-IEA-  
GO:0046878positive regulation of saliva secretion-IEA-  
GO:0048265response to pain-IEA-  
GO:0050671positive regulation of lymphocyte proliferation-IEA-  
GO:0051496positive regulation of stress fiber assembly-IEA-  
GO:1990090cellular response to nerve growth factor stimulus-IEA-  
GO:2000854positive regulation of corticosterone secretion-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IBA21873635  
GO:0005886plasma membrane-IEA-  
GO:0030424axon-IEA-  
GO:0043025neuronal cell body-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-373076Class A/1 (Rhodopsin-like receptors)TAS
R-HSA-375276Peptide ligand-binding receptorsTAS
R-HSA-380095Tachykinin receptors bind tachykininsTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-416476G alpha (q) signalling eventsTAS
R-HSA-500792GPCR ligand bindingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
20572039Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas. (2010 Oct 1)Paun BCCancer