Gene: TCTE3

6991
TCTEX1D3
t-complex-associated-testis-expressed 3
protein-coding
6q27
Ensembl:ENSG00000184786 MIM:186977 Vega:OTTHUMG00000016068 UniprotKB:Q8IZS6
NC_000006.12
SNP Mapped
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.146e-1 (AD)  5.832e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs9478099chr6:169730151 (GRCh38.p7)G>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
IPPK0.628
PXMP40.617
SMCR80.612
FAM156B0.612
GPATCH80.611
CYP51A10.608
POLR3D0.606
TNPO30.604
ZNF6230.601
TSTD20.601

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FMO3-0.298
PTGDR2-0.294
ASPN-0.276
RSPO1-0.276
MUSTN1-0.272
GRHL2-0.27
RERGL-0.266
P2RY14-0.256
TCL1A-0.256
COX4I2-0.252

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of TCTE3 mRNA"25270620
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TCTE3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TCTE3 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of TCTE3 mRNA17562736
D001564Benzo(a)pyreneAHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of TCTE3 mRNA]15034205
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of TCTE3 mRNA15034205|2222880
C006780bisphenol Abisphenol A results in decreased expression of TCTE3 mRNA25181051
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TCTE3 mRNA18560533
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of TCTE3 mRNA23650126
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TCTE3 mRNA20938992
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in decreased expression of TCTE3 mRNA23649840
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TCTE3 mRNA20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TCTE3 mRNA20938992
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of TCTE3 mRNA28001369
C046012pentanalpentanal results in decreased expression of TCTE3 mRNA26079696
D011192Potassium DichromatePotassium Dichromate results in increased expression of TCTE3 mRNA23608068
D012822Silicon DioxideSilicon Dioxide results in decreased expression of TCTE3 mRNA19073995
D013749TetrachlorodibenzodioxinAHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TCTE3 mRNA]15034205
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of TCTE3 mRNA15034205
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TCTE3 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of TCTE3 mRNA23179753|2438349
D014635Valproic AcidValproic Acid results in decreased methylation of TCTE3 gene29154799
D014635Valproic AcidValproic Acid affects the expression of TCTE3 mRNA17292431
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of TCTE3 gene25560391
D014750VincristineVincristine results in decreased expression of TCTE3 mRNA23649840

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003774motor activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IEA-  
GO:0005874microtubule-IEA-  
GO:0016020membrane-IEA-  
GO:0030286dynein complex-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1852241Organelle biogenesis and maintenanceTAS
R-HSA-5617833Cilium AssemblyTAS
R-HSA-5620924Intraflagellar transportTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal