Gene: NR2F1

7025
BBOAS|BBSOAS|COUP-TFI|COUPTF1|EAR-3|EAR3|ERBAL3|NR2F2|SVP44|TCFCOUP1|TFCOUP1
nuclear receptor subfamily 2 group F member 1
protein-coding
5q15
Ensembl:ENSG00000175745 MIM:132890 Vega:OTTHUMG00000119079 UniprotKB:P10589
NG_034119.1
PubMed
ND
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.015e-2 (AD)  4.602e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GOLGA7B0.911
CACNG70.905
SIRPA0.894
DTX30.891
KNDC10.89
TOM1L20.89
MLST80.889
CMTM40.889
ABHD80.888
ZBTB180.887

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.739
OR4F29-0.689
TFPI2-0.454
DPPA4-0.399
C2orf83-0.38
ABCA13-0.379
MROH5-0.377
KCNJ15-0.372
CEACAM3-0.371
FCRLA-0.37

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB06732beta-NaphthoflavoneSmall Molecule6051-87-2ExperimentalTarget
ID Drug Name Action PubMed
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of NR2F1 mRNA"19162173
C0388644-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid"4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of NR2F1 mRNA"15583048
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NR2F1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NR2F1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NR2F1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NR2F1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NR2F1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NR2F1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of NR2F1 mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of NR2F1 mRNA17562736
C011512alpha-naphthoflavone[alpha-naphthoflavone binds to AHR protein] which binds to NR2F1 protein10620335
D000643Ammonium ChlorideAmmonium Chloride affects the expression of NR2F1 mRNA16483693
D016718Arachidonic AcidArachidonic Acid results in decreased expression of NR2F1 mRNA16704987
D001104ArbutinArbutin results in increased expression of NR2F1 mRNA17103032
D001280AtrazineAtrazine results in decreased expression of NR2F1 mRNA22378314
C547126AZM551248AZM551248 results in increased expression of NR2F1 mRNA22323515
D019324beta-Naphthoflavone[beta-Naphthoflavone binds to AHR protein] which binds to NR2F1 protein10620335
D001564Benzo(a)pyreneBenzo(a)pyrene affects the reaction [AHR protein binds to NR2F1 promoter]19654925
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NR2F1 mRNA"19150397
D004958Estradiol[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NR2F1 mRNA20823114
D004958EstradiolEstradiol results in increased expression of NR2F1 mRNA19484750
C044887beta-methylcholinebeta-methylcholine affects the expression of NR2F1 mRNA21179406
C006780bisphenol Abisphenol A affects the methylation of NR2F1 promoter27334623
C006780bisphenol Abisphenol A results in decreased expression of NR2F1 mRNA25181051
C018475butyraldehydebutyraldehyde results in decreased expression of NR2F1 mRNA26079696
C584509C646 compoundC646 compound results in decreased expression of NR2F1 mRNA26191083
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of NR2F1 mRNA18974090
D002220CarbamazepineCarbamazepine affects the expression of NR2F1 mRNA24752500
D002330CarmustineNR2F1 mRNA affects the susceptibility to Carmustine16365179
C084597chlorcyclizinechlorcyclizine results in increased expression of NR2F1 mRNA21058326
D002713Chlorine[Ozone co-treated with Chlorine] results in increased expression of NR2F1 mRNA18636392
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NR2F1 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in decreased expression of NR2F1 mRNA26272509
C039671ciglitazoneNR2F1 protein promotes the reaction [[SR 11237 co-treated with ciglitazone] results in increased expression of RARB protein]12839938
C018021cobaltous chloridecobaltous chloride results in decreased expression of NR2F1 mRNA19376846
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of NR2F1 mRNA20971185
D019327Copper SulfateCopper Sulfate results in decreased expression of NR2F1 mRNA19549813
D016572CyclosporineCyclosporine results in decreased expression of NR2F1 mRNA20106945|2556210
C014347decitabinedecitabine results in decreased expression of NR2F1 mRNA19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of NR2F1 mRNA]19363521
D003907DexamethasoneDexamethasone results in increased expression of NR2F1 mRNA19022236
D003907DexamethasoneDexamethasone results in decreased expression of NR2F1 mRNA22733784
D003907DexamethasoneDexamethasone results in decreased expression of NR2F1 mRNA20032058
D003907DexamethasoneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of NR2F1 mRNA]20032058
D003994Bucladesine[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NR2F1 mRNA20823114
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of NR2F1 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of NR2F1 mRNA27392435
D004008DiclofenacDiclofenac affects the expression of NR2F1 mRNA24752500
C000944dicrotophosdicrotophos results in increased expression of NR2F1 mRNA28302478
D002117CalcitriolCalcitriol results in increased expression of NR2F1 mRNA16002434
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of NR2F1 mRNA"19480007
D0198131,2-Dimethylhydrazine"[APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in decreased expression of NR2F1 mRNA"27840820
D004147DioxinsDioxins affects the expression of NR2F1 mRNA20463971
C118739entinostatentinostat results in decreased expression of NR2F1 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NR2F1 mRNA"27188386
D000431EthanolEthanol results in decreased expression of NR2F1 mRNA15353170
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of NR2F1 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of NR2F1 mRNA15576828|1755790
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of NR2F1 mRNA23550701
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in decreased expression of NR2F1 mRNA23649840
D005632FructoseFructose affects the reaction [NR2F1 protein binds to SHBG promoter]17992261
D005947GlucoseGlucose affects the reaction [NR2F1 protein binds to SHBG promoter]17992261
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of NR2F1 mRNA22634610
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of NR2F1 mRNA27392435
D008345ManganeseManganese results in decreased expression of NR2F1 mRNA23976782
D008345ManganeseManganese results in increased methylation of NR2F1 promoter23976782
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NR2F1 mRNA20823114
C042720mercuric bromidemercuric bromide results in decreased expression of NR2F1 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NR2F1 mRNA"27188386
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of NR2F1 mRNA23103053
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of NR2F1 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of NR2F1 mRNA23649840
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of NR2F1 mRNA24810058
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased expression of NR2F1 protein24625837
C523799MRK 003NR2F1 results in increased susceptibility to MRK 00319903844
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of NR2F1 mRNA"25554681
C570897NSC668394NSC668394 results in decreased expression of NR2F1 mRNA27137931
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of NR2F1 mRNA20971185
C030110oxaliplatinoxaliplatin results in increased expression of NR2F1 mRNA17762391
D010126Ozone[Ozone co-treated with Chlorine] results in increased expression of NR2F1 mRNA18636392
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of NR2F1 mRNA26272509
D010269ParaquatParaquat results in increased expression of NR2F1 mRNA18198484
D010575PesticidesPesticides results in decreased methylation of NR2F1 gene28396702
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of NR2F1 mRNA26272509
D010672PhenytoinPhenytoin results in increased expression of NR2F1 mRNA20345932
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of NR2F1 mRNA19710929
C006253pirinixic acidpirinixic acid results in increased expression of NR2F1 mRNA12832660
D010936Plant ExtractsPlant Extracts results in decreased expression of NR2F1 mRNA23557933
D011441PropylthiouracilPropylthiouracil results in increased expression of NR2F1 mRNA24780913
D015474IsotretinoinIsotretinoin results in increased expression of NR2F1 mRNA20436886
C078903seocalcitolseocalcitol results in increased expression of NR2F1 mRNA12040012
D012834SilverSilver results in decreased expression of NR2F1 mRNA27131904
C017947sodium arsenitesodium arsenite results in decreased expression of NR2F1 mRNA16014739
D053260SootSoot results in decreased expression of NR2F1 mRNA26551751
C087130SR 11237NR2F1 protein promotes the reaction [[SR 11237 co-treated with ciglitazone] results in increased expression of RARB protein]12839938
D013629TamoxifenTamoxifen results in decreased activity of NR2F1 protein20937368
C047246temozolomideNR2F1 mRNA affects the susceptibility to temozolomide16365179
D013739TestosteroneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of NR2F1 mRNA]20032058
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of NR2F1 mRNA25172293
D013749TetrachlorodibenzodioxinNR2F1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]10620335
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of NR2F1 mRNA24058054
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the reaction [AHR protein binds to NR2F1 promoter]19654925
D013974ThyroxineThyroxine affects the expression of NR2F1 mRNA17403546
D014212TretinoinTretinoin results in increased expression of NR2F1 mRNA15977162
D014212TretinoinTretinoin results in increased expression of NR2F1 mRNA20530235
D014212TretinoinTretinoin results in increased expression of NR2F1 mRNA22906706
C034613triacsin Ctriacsin C results in decreased expression of NR2F1 mRNA16704987
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of NR2F1 mRNA24935251|2627250
C012589trichostatin Atrichostatin A results in decreased expression of NR2F1 mRNA15901671
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of NR2F1 mRNA23537331
D014520UrethaneUrethane results in increased expression of NR2F1 mRNA28818685
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR2F1 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of NR2F1 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of NR2F1 mRNA23179753|2438349
D014635Valproic AcidValproic Acid results in increased methylation of NR2F1 gene29154799
D014635Valproic AcidValproic Acid results in decreased expression of NR2F1 mRNA15901671
D014638VanadatesVanadates results in increased expression of NR2F1 mRNA22714537
D014810Vitamin EVitamin E results in increased expression of NR2F1 mRNA19244175

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding-IDA10644740  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0001078transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IDA10644740  
GO:0003700DNA-binding transcription factor activity-IDA10644740  
GO:0003707steroid hormone receptor activity-IEA-  
GO:0003713transcription coactivator activity-TAS2739739  
GO:0004879nuclear receptor activity-IEA-  
GO:0005515protein binding-IPI1517211  8551580  11043578  
GO:0008270zinc ion binding-IEA-  
GO:0043565sequence-specific DNA binding-IDA10644740  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IDA10644740  
GO:0006367transcription initiation from RNA polymerase II promoter-TAS-  
GO:0007165signal transduction-TAS2739739  
GO:0030522intracellular receptor signaling pathway-IEA-  
GO:0043401steroid hormone mediated signaling pathway-IEA-  
GO:1903508positive regulation of nucleic acid-templated transcription-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA10644740  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005829cytosol-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-383280Nuclear Receptor transcription pathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28542447Exploratory plasma proteomic analysis in a randomized crossover trial of aspirin among healthy men and women. (2017)Wang XPLoS One
24847019In utero exposure to cigarette smoke dysregulates human fetal ovarian developmental signalling. (2014 Jul)Fowler PAHum Reprod