Gene: TGFBI

7045
BIGH3|CDB1|CDG2|CDGG1|CSD|CSD1|CSD2|CSD3|EBMD|LCD1
transforming growth factor beta induced
protein-coding
5q31.1
Ensembl:ENSG00000120708 MIM:601692 Vega:OTTHUMG00000163213 UniprotKB:Q15582
NG_012646.1
PubMed|SNP Mapped
ND|AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.237e-1 (AD)  4.822e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2107331chr5:136041660 (GRCh38.p7)C>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg10187927chr5:135364060TGFBI4.560e-11Maternal smoking in pregnancy27040690
cg18331412chr5:135364986TGFBI1.900e-8Maternal smoking in pregnancy27040690
cg10187927chr5:135364060TGFBI3.000e-12Maternal smoking in pregnancy27040690
cg18331412chr5:135364986TGFBI7.080e-8Maternal smoking in pregnancy27040690
cg10187927chr5:135364060TGFBI2.110e-14Maternal smoking in pregnancy27040690
cg18331412chr5:135364986TGFBI2.480e-8Maternal smoking in pregnancy27040690
cg05838308chr5:135367668TGFBI2.740e-15Alcohol consumption per day27843151

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CTSC0.786
GPR650.783
CYBB0.77
MS4A4A0.77
TLR10.768
TNFAIP80.763
DAPP10.76
LRRC250.76
LILRA10.759
IKZF10.756

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FEZF2-0.456
HHATL-0.444
MYH7B-0.428
ASPDH-0.401
NXPH3-0.397
PNPLA7-0.389
ATP2C2-0.388
DBP-0.384
PLA2G6-0.384
MYADML2-0.381

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of TGFBI mRNA19933214
C0131862,3-pentanedione"2,3-pentanedione results in increased expression of TGFBI mRNA"25710175
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of TGFBI mRNA"21346803
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TGFBI mRNA"22262711
C0144643,4-dichloroaniline"3,4-dichloroaniline results in decreased expression of TGFBI mRNA"24172598
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TGFBI mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TGFBI mRNA"27188386
C1052604-tert-octylphenol4-tert-octylphenol results in decreased expression of TGFBI mRNA17011747
C1052604-tert-octylphenol4-tert-octylphenol results in increased expression of TGFBI mRNA17011747
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TGFBI mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TGFBI mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of TGFBI mRNA25458485
D000082AcetaminophenAcetaminophen results in decreased expression of TGFBI mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of TGFBI mRNA17562736
D020106AcrylamideAcrylamide affects the expression of TGFBI mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of TGFBI mRNA19770486
D000638AmiodaroneAmiodarone affects the expression of TGFBI mRNA19483382
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of TGFBI mRNA"22863853
D001151ArsenicArsenic affects the methylation of TGFBI gene25304211
C015001arsenitearsenite results in decreased methylation of TGFBI promoter23974009
D001194AsbestosAsbestos results in decreased expression of TGFBI mRNA16920672
C547126AZM551248AZM551248 results in increased expression of TGFBI mRNA22323515
D001507BeclomethasoneBeclomethasone results in increased expression of TGFBI mRNA23656298
D001553BenzbromaroneBenzbromarone affects the expression of TGFBI mRNA19483382
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TGFBI mRNA25566086
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of TGFBI mRNA19619570
D004958EstradiolEstradiol results in increased expression of TGFBI mRNA19619570
D004958EstradiolEstradiol results in decreased expression of TGFBI mRNA15289156
C006780bisphenol Abisphenol A affects the expression of TGFBI mRNA21786754
C006780bisphenol Abisphenol A affects the expression of TGFBI mRNA26063408
C006780bisphenol Abisphenol A results in increased expression of TGFBI mRNA27312807
C006780bisphenol Abisphenol A results in increased expression of TGFBI mRNA24534842
C006780bisphenol Abisphenol A results in decreased expression of TGFBI mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of TGFBI gene28505145
D019256Cadmium ChlorideCadmium Chloride results in decreased methylation of TGFBI promoter22457795
D002220CarbamazepineCarbamazepine affects the expression of TGFBI mRNA25979313
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of TGFBI mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of TGFBI mRNA27339419
C100187chloropicrinchloropicrin results in decreased expression of TGFBI mRNA26352163
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TGFBI mRNA20938992
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of TGFBI mRNA28472532
D002994ClofibrateClofibrate affects the expression of TGFBI mRNA19483382
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of TGFBI mRNA17602206
C018021cobaltous chloridecobaltous chloride results in decreased secretion of TGFBI protein22079246
C018021cobaltous chloridecobaltous chloride results in decreased expression of TGFBI mRNA24386269
D019327Copper SulfateCopper Sulfate results in decreased expression of TGFBI mRNA19549813
C029892cupric chloridecupric chloride results in increased expression of TGFBI mRNA21072851
D003471CuprizoneCuprizone results in decreased expression of TGFBI mRNA27523638
D003471CuprizoneCuprizone results in increased expression of TGFBI mRNA26577399
D016572CyclosporineCyclosporine results in decreased expression of TGFBI mRNA27989131
C561627dabrafenib"dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TGFBI mRNA]"29042256
C561627dabrafenib"dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TGFBI protein]"29042256
C561627dabrafenibdabrafenib inhibits the reaction [TGFBI protein results in increased expression of ICAM1 protein]29042256
C561627dabrafenibdabrafenib inhibits the reaction [TGFBI protein results in increased expression of SELE protein]29042256
C561627dabrafenibdabrafenib inhibits the reaction [TGFBI protein results in increased expression of VCAM1 protein]29042256
C014347decitabinedecitabine results in increased expression of TGFBI mRNA21856257
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of TGFBI mRNA]27941970
D003907DexamethasoneDexamethasone results in decreased expression of TGFBI mRNA25047013
D002945CisplatinTGFBI mRNA results in decreased susceptibility to Cisplatin25199881
C121718dicyclanildicyclanil results in decreased expression of TGFBI mRNA15664270
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of TGFBI mRNA26924002
D004041Dietary FatsDietary Fats results in decreased expression of TGFBI mRNA18042831|1845759
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of TGFBI mRNA17602206
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of TGFBI mRNA19638242
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of TGFBI mRNA15289156
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of TGFBI mRNA17011747
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of TGFBI mRNA17011747
C024629dimethyl phthalatedimethyl phthalate affects the expression of TGFBI mRNA26924002
D004237DiuronDiuron metabolite results in decreased expression of TGFBI mRNA24172598
D004237DiuronDiuron results in increased expression of TGFBI mRNA21551480
D004317DoxorubicinDoxorubicin affects the expression of TGFBI protein29385562
D004317DoxorubicinTGFBI mRNA results in decreased susceptibility to Doxorubicin25199881
D004656EnalaprilEnalapril results in decreased secretion of TGFBI protein18682491
D004656Enalapril[eplerenone co-treated with Enalapril] results in decreased secretion of TGFBI protein18682491
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of TGFBI mRNA22079256
C414690eplerenone[eplerenone co-treated with Enalapril] results in decreased secretion of TGFBI protein18682491
C414690eplerenoneeplerenone results in decreased secretion of TGFBI protein18682491
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TGFBI mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of TGFBI mRNA16174780
D005001EthionineEthionine affects the expression of TGFBI mRNA19483382
C000499ferric oxideferric oxide analog results in increased expression of TGFBI mRNA24525745
D005472FluorouracilTGFBI protein affects the susceptibility to Fluorouracil16217747
D005485FlutamideFlutamide results in decreased expression of TGFBI mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TGFBI mRNA20938992
C069837fullerene C60fullerene C60 results in decreased expression of TGFBI mRNA19167457
D019833GenisteinGenistein results in decreased expression of TGFBI mRNA15289156
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of TGFBI mRNA22634610
C004312glycidolglycidol results in decreased expression of TGFBI mRNA24915197
C412815GW 4064GW 4064 results in increased expression of TGFBI mRNA26655953
D017313FenretinideFenretinide results in decreased expression of TGFBI mRNA28973697
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TGFBI mRNA25613284
C051890irinotecanirinotecan analog results in decreased expression of TGFBI mRNA18927307
C544151jinfukangjinfukang results in increased expression of TGFBI mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of TGFBI mRNA23086925
C410337K 7174K 7174 results in increased expression of TGFBI mRNA24086573
D007854LeadLead results in decreased expression of TGFBI mRNA19921347
C533894LG 100815LG 100815 results in increased expression of TGFBI mRNA16951191
C440499lipopolysaccharide, Escherichia coli O111 B4"dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TGFBI mRNA]"29042256
C440499lipopolysaccharide, Escherichia coli O111 B4"dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TGFBI protein]"29042256
C440499lipopolysaccharide, Escherichia coli O111 B4"ITGB5 protein affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TGFBI protein]"27287417|2904225
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TGFBI mRNA"27287417|2904225
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TGFBI protein"27287417|2904225
C440499lipopolysaccharide, Escherichia coli O111 B4"Triterpenes inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TGFBI mRNA]"27287417
C440499lipopolysaccharide, Escherichia coli O111 B4"Triterpenes inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TGFBI protein]"27287417
D008070LipopolysaccharidesLipopolysaccharides affects the expression of TGFBI mRNA28070326
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TGFBI mRNA27887929
D008070LipopolysaccharidesLipopolysaccharides results in increased secretion of TGFBI protein27887929
D008070LipopolysaccharidesPlant Extracts affects the reaction [Lipopolysaccharides affects the expression of TGFBI mRNA]28070326
D008070LipopolysaccharidesTriterpenes inhibits the reaction [Lipopolysaccharides results in increased expression of TGFBI mRNA]27887929
D008070LipopolysaccharidesTriterpenes inhibits the reaction [Lipopolysaccharides results in increased secretion of TGFBI protein]27887929
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TGFBI mRNA27339419
D058185Magnetite NanoparticlesMagnetite Nanoparticles results in increased expression of TGFBI mRNA24525745
D008627Mercuric ChlorideMercuric Chloride affects the expression of TGFBI mRNA20353558
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TGFBI mRNA20938992
D008727MethotrexateTGFBI mRNA results in decreased susceptibility to Methotrexate25199881
D016685MitomycinMitomycin results in decreased expression of TGFBI mRNA18615204
D016685MitomycinMitomycin results in decreased expression of TGFBI protein18615204
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased expression of TGFBI mRNA22108045
C517284monomethyl phthalatemonomethyl phthalate affects the expression of TGFBI mRNA26924002
C523799MRK 003MRK 003 results in decreased expression of TGFBI mRNA21169257
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of TGFBI mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of TGFBI mRNA"25554681
C017096n-butoxyethanoln-butoxyethanol results in decreased expression of TGFBI mRNA19812364
C051752nefazodonenefazodone results in decreased expression of TGFBI mRNA24136188
D009532NickelNickel results in increased expression of TGFBI mRNA12540486
C022838nickel chloridenickel chloride results in decreased expression of TGFBI mRNA24612858
C028007nickel monoxidenickel monoxide results in decreased expression of TGFBI mRNA19167457
C012655nimesulidenimesulide results in decreased expression of TGFBI mRNA24136188
C062198octa-2,4,6-trienoic acid"octa-2,4,6-trienoic acid results in increased expression of TGFBI mRNA"16951191
D009853OmeprazoleOmeprazole affects the expression of TGFBI mRNA19483382
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of TGFBI mRNA25729387
C030110oxaliplatinoxaliplatin results in decreased expression of TGFBI mRNA25729387
D010100OxygenOxygen deficiency results in increased expression of TGFBI mRNA26516004
D017239PaclitaxelTGFBI mRNA results in decreased susceptibility to Paclitaxel25199881
D000073878Palm OilPalm Oil results in decreased expression of TGFBI mRNA18042831
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TGFBI mRNA"27188386
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of TGFBI mRNA18692542
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in decreased expression of TGFBI mRNA]19482888
D010634PhenobarbitalPhenobarbital results in decreased expression of TGFBI mRNA19482888
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TGFBI mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of TGFBI mRNA26272509
C006253pirinixic acidpirinixic acid results in decreased expression of TGFBI mRNA17426115
C006253pirinixic acidpirinixic acid affects the expression of TGFBI mRNA19483382
D010936Plant ExtractsPlant Extracts affects the reaction [Lipopolysaccharides affects the expression of TGFBI mRNA]28070326
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of TGFBI mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of TGFBI mRNA22714537
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of TGFBI mRNA22079256
D011192Potassium DichromatePotassium Dichromate results in decreased expression of TGFBI protein23718831
D011374ProgesteroneProgesterone results in decreased expression of TGFBI mRNA23012394
D011374ProgesteroneProgesterone results in increased expression of TGFBI17510236
D011441PropylthiouracilPropylthiouracil affects the expression of TGFBI mRNA19483382
D011441PropylthiouracilPropylthiouracil results in decreased expression of TGFBI mRNA24780913
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride affects the expression of TGFBI mRNA14699072
D020849Raloxifene Hydrochloride[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TGFBI mRNA19059307
D020849Raloxifene Hydrochloride[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFBI mRNA19059307
C059514resveratrolresveratrol results in decreased expression of TGFBI mRNA25888808
D012715Sesame OilSesame Oil results in decreased expression of TGFBI mRNA29191790
D012822Silicon DioxideSilicon Dioxide analog results in decreased secretion of TGFBI protein25895662
D012906SmokeSmoke results in increased expression of TGFBI mRNA21095227
C009277sodium arsenatesodium arsenate results in decreased expression of TGFBI mRNA16882884|2392266
C016104sodium bichromatesodium bichromate results in decreased expression of TGFBI mRNA24612858
C016104sodium bichromatesodium bichromate results in decreased expression of TGFBI mRNA17685462
D012999SomanSoman results in increased expression of TGFBI mRNA19281266
D053260SootSoot results in increased expression of TGFBI mRNA22461453
D013629Tamoxifen[Tamoxifen co-treated with ESR1 protein] results in decreased expression of TGFBI mRNA19059307
D013629Tamoxifen[Tamoxifen co-treated with ESR2 protein] results in increased expression of TGFBI mRNA19059307
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in decreased expression of TGFBI mRNA15885361
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of TGFBI mRNA25172293
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of TGFBI mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TGFBI mRNA19619570|2010694
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TGFBI mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TGFBI mRNA19933214
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of TGFBI mRNA21215274
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TGFBI mRNA15644576
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TGFBI mRNA25613284
D013792ThalidomideThalidomide results in decreased expression of TGFBI mRNA26006729|2621778
D013853ThioacetamideThioacetamide affects the expression of TGFBI mRNA19483382
C009495titanium dioxidetitanium dioxide results in increased expression of TGFBI mRNA23557971|2776080
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TGFBI mRNA28065790
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TGFBI mRNA18087596
D019772TopotecanTGFBI mRNA results in decreased susceptibility to Topotecan25199881
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of TGFBI mRNA25729387
D019772TopotecanTopotecan results in decreased expression of TGFBI mRNA25729387
C496197trans-10,cis-12-conjugated linoleic acid"trans-10,cis-12-conjugated linoleic acid results in decreased expression of TGFBI mRNA"17951470
D014212TretinoinTretinoin results in decreased expression of TGFBI mRNA21934132
D014212TretinoinTretinoin results in increased expression of TGFBI mRNA16951191|2383079
C012589trichostatin Atrichostatin A results in increased expression of TGFBI mRNA15901671
C012589trichostatin Atrichostatin A results in decreased expression of TGFBI mRNA24935251
C012589trichostatin Atrichostatin A results in decreased expression of TGFBI mRNA15901671
D014315Triterpenes"Triterpenes inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TGFBI mRNA]"27287417
D014315Triterpenes"Triterpenes inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TGFBI protein]"27287417
D014315TriterpenesTriterpenes inhibits the reaction [Lipopolysaccharides results in increased expression of TGFBI mRNA]27887929
D014315TriterpenesTriterpenes inhibits the reaction [Lipopolysaccharides results in increased secretion of TGFBI protein]27887929
D014315TriterpenesTriterpenes inhibits the reaction [TGFBI protein results in increased expression of ICAM1 protein]27287417|2788792
D014315TriterpenesTriterpenes inhibits the reaction [TGFBI protein results in increased expression of SELE protein]27287417|2788792
D014315TriterpenesTriterpenes inhibits the reaction [TGFBI protein results in increased expression of VCAM1 protein]27287417|2788792
D014315TriterpenesTriterpenes inhibits the reaction [TGFBI protein results in increased phosphorylation of and affects the localization of RELA protein]27887929
D014315TriterpenesTriterpenes inhibits the reaction [TGFBI protein results in increased phosphorylation of MAPK1 protein]27887929
D014315TriterpenesTriterpenes inhibits the reaction [TGFBI protein results in increased phosphorylation of MAPK3 protein]27887929
D014315TriterpenesTriterpenes inhibits the reaction [TGFBI protein results in increased secretion of IL6 protein]27887929
D014315TriterpenesTriterpenes inhibits the reaction [TGFBI protein results in increased secretion of ITGAV protein alternative form]27887929
D014315TriterpenesTriterpenes inhibits the reaction [TGFBI protein results in increased secretion of TNF protein]27887929
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in decreased expression of TGFBI mRNA15885361
D014635Valproic AcidValproic Acid results in increased expression of TGFBI mRNA15901671
D014635Valproic AcidValproic Acid results in decreased expression of TGFBI mRNA24935251
D014635Valproic AcidValproic Acid results in increased expression of TGFBI mRNA24896083
D014635Valproic AcidValproic Acid results in decreased expression of TGFBI mRNA15901671
D014638VanadatesVanadates results in increased expression of TGFBI mRNA22714537
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of TGFBI mRNA19165385
D014750VincristineTGFBI mRNA results in decreased susceptibility to Vincristine25199881
C029297vinylidene chloridevinylidene chloride results in increased expression of TGFBI mRNA26682919
D014800VitalliumVitallium analog results in decreased expression of TGFBI mRNA23825117
D014810Vitamin EVitamin E results in increased expression of TGFBI mRNA19244175

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005178integrin binding-IEA-  
GO:0005515protein binding-IPI19478074  25416956  
GO:0005518collagen binding-IPI19478074  
GO:0050839cell adhesion molecule binding-IBA21873635  
GO:0050840extracellular matrix binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001525angiogenesis-IEP11866539  
GO:0002062chondrocyte differentiation-IEA-  
GO:0007155cell adhesion-IBA21873635  
GO:0007155cell adhesion-IEA-  
GO:0007162negative regulation of cell adhesion-TAS8024701  
GO:0007601visual perception-IEA-  
GO:0008283cell proliferation-IEA-  
GO:0030198extracellular matrix organization-IBA21873635  
GO:0044267cellular protein metabolic process-TAS-  
GO:0050896response to stimulus-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-HDA27068509  
GO:0005576extracellular region-TAS-  
GO:0005604basement membrane-IEA-  
GO:0005615extracellular space-IBA21873635  
GO:0005615extracellular space-IDA19478074  
GO:0005802trans-Golgi network-IDA19478074  
GO:0005886plasma membrane-TAS-  
GO:0062023collagen-containing extracellular matrix-HDA23979707  27559042  
GO:0062023collagen-containing extracellular matrixcolocalizes_withHDA20551380  
GO:0062023collagen-containing extracellular matrixcolocalizes_withISS22261194  
GO:0070062extracellular exosome-HDA19199708  21362503  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-392499Metabolism of proteinsTAS
R-HSA-977225Amyloid fiber formationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
21071578A migration signature and plasma biomarker panel for pancreatic adenocarcinoma. (2011 Jan)Balasenthil SCancer Prev Res (Phila)