Gene info: ID 7052

Gene: TGM2

GENE ID: 7052

Synonyms: TG(C)|TGC

Description: transglutaminase 2

Gene type: protein-coding

Location: 20q11.23

dbXrefs: Ensembl:ENSG00000198959 MIM:190196 Vega:OTTHUMG00000032437 UniprotKB:P21980

RefSeq: NC_000020.11

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND

# Publications: 1

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 1.164e-1 (AD) 7.378e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
ACSL5	0.915
FGR	0.882
IL4R	0.88
STARD8	0.868
VWF	0.866
ERG	0.86
ICAM2	0.856
FLT1	0.856
PLA1A	0.852
CFB	0.851

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
CRH	-0.488
CPLX3	-0.447
SMIM18	-0.442
ZSCAN1	-0.437
ABCC12	-0.427
CORT	-0.424
MARCH4	-0.419
NEUROD6	-0.417
KCNIP3	-0.411
SPEF1	-0.411

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB04315	Guanosine-5'-Diphosphate	Small Molecule	146-91-8	Experimental	Target
DB00130	L-Glutamine	Small Molecule	56-85-9	Approved\|Investigational\|Nutraceutical	Enzyme

ID	Drug Name	Action	PubMed
C026486	1,2,5,6-dibenzanthracene	"1,2,5,6-dibenzanthracene results in decreased expression of TGM2 mRNA"	16269432
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of TGM2 mRNA"	28903501
C016614	1-nitronaphthalene	1-nitronaphthalene metabolite binds to TGM2 protein	16453347
C548651	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of TGM2 mRNA	19933214
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	18295389
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	18295389
C585004	2-monochloropropanediol	2-monochloropropanediol results in increased expression of TGM2 mRNA	28522335
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TGM2 mRNA"	23196670
C054189	3,5-di-tert-butylchalcone 4'-carboxylic acid	"3,5-di-tert-butylchalcone 4'-carboxylic acid results in increased activity of TGM2 protein"	2884032
C549543	3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid	3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid analog results in increased expression of TGM2 mRNA	25716159
C038864	4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid	"4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of TGM2 mRNA"	10910994
C038864	4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid	"4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of TGM2 protein"	16158052
C038864	4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid	"Tetrachlorodibenzodioxin inhibits the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of TGM2 mRNA]"	10910994
C064545	4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid	"[4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid co-treated with CD 2425] results in increased expression of TGM2 mRNA"	9516142
C064545	4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid	"[4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid co-treated with CD 2425] results in increased expression of TGM2 protein"	9516142
C064545	4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid	"4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid inhibits the reaction [Tretinoin results in increased expression of TGM2 mRNA]"	9516142
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TGM2 mRNA"	27188386
C002202	4-oxoretinoic acid	4-oxoretinoic acid results in increased expression of TGM2 mRNA	17034753
C041819	4-oxoretinol	4-oxoretinol results in increased expression of TGM2 mRNA	17034753
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TGM2 mRNA"	27188386
C003001	7-ketocholesterol	7-ketocholesterol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TGM2 mRNA]	16480812
D000082	Acetaminophen	Acetaminophen results in decreased expression of TGM2 mRNA	21420995
D000082	Acetaminophen	Acetaminophen results in increased expression of TGM2 mRNA	25704631\|2906747
D000082	Acetaminophen	Acetaminophen affects the expression of TGM2 mRNA	17562736
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Particulate Matter analog results in decreased activity of TGM2 protein]	15541757
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in decreased activity of TGM2 protein]	15541757
D020106	Acrylamide	Acrylamide results in decreased expression of TGM2 mRNA	15749267
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of TGM2 mRNA	27153756
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of TGM2 mRNA	19770486
C096920	AGN 193109	AGN 193109 inhibits the reaction [Tretinoin results in increased expression of TGM2 protein]	16158052
C103303	alitretinoin	[alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [HIST3H3 protein modified form binds to TGM2 gene]	15964820
C103303	alitretinoin	[alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [HIST4H4 protein modified form binds to TGM2 gene]	15964820
C103303	alitretinoin	alitretinoin results in increased activity of TGM2 protein	9516142
C103303	alitretinoin	alitretinoin results in increased expression of TGM2 mRNA	15964820\|1703475
C103303	alitretinoin	alitretinoin results in increased expression of TGM2 protein	15964820\|1615805
C103303	alitretinoin	Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of TGM2 mRNA]	15964820
C103303	alitretinoin	Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of TGM2 protein]	15964820
C103303	alitretinoin	periodate-oxidized adenosine inhibits the reaction [alitretinoin results in increased expression of TGM2 mRNA]	15964820
C103303	alitretinoin	periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of TGM2 mRNA]]	15964820
C103303	alitretinoin	Vitamin D promotes the reaction [alitretinoin results in increased expression of TGM2 mRNA]	15964820
C103303	alitretinoin	alitretinoin results in increased expression of TGM2 mRNA	28689802
D000517	alpha-Chlorohydrin	alpha-Chlorohydrin results in increased expression of TGM2 mRNA	28522335
C068073	Am 580	[Am 580 co-treated with CD 2425] results in increased activity of TGM2 protein	9516142
C068073	Am 580	Am 580 results in increased activity of TGM2 protein	2884032
C068073	Am 580	Am 580 results in increased expression of TGM2 mRNA	16982809
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of TGM2 mRNA	16483693
C102351	apicidin	apicidin inhibits the reaction [Dexamethasone results in increased expression of TGM2 mRNA]	23946490
C006632	arsenic trioxide	arsenic trioxide inhibits the reaction [Tretinoin results in increased expression of TGM2 protein]	11133770\|9450572
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased expression of TGM2 mRNA"	25351596
C005948	astaxanthine	astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TGM2 mRNA]	16964424
C547126	AZM551248	AZM551248 results in increased expression of TGM2 mRNA	22323515
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of TGM2 mRNA	22178795
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of TGM2 mRNA	26238291
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of TGM2 mRNA	19770486
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of TGM2 mRNA	22228805
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TGM2 mRNA"	26238291
D019207	beta Carotene	beta Carotene results in increased expression of TGM2 mRNA	17034753
D004958	Estradiol	ESR1 protein affects the reaction [Estradiol results in increased expression of TGM2 mRNA]	14699072
D004958	Estradiol	Estradiol affects the expression of TGM2 mRNA	14699072
D004958	Estradiol	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of TGM2 mRNA	19619570
D004958	Estradiol	Estradiol results in increased expression of TGM2 mRNA	19619570\|2532141
D004958	Estradiol	[Progesterone co-treated with Estradiol] results in decreased expression of TGM2 mRNA	17404688
D004958	Estradiol	Estradiol results in increased expression of TGM2 mRNA	19484750
D004958	Estradiol	[bisphenol A co-treated with Estradiol] results in decreased expression of TGM2 mRNA	26496021
C095105	bexarotene	bexarotene results in increased expression of TGM2 mRNA	17178900
C095105	bexarotene	bexarotene results in increased expression of TGM2 mRNA	21622945\|2593259
C095105	bexarotene	diazepinylbenzoic acid inhibits the reaction [bexarotene results in increased expression of TGM2 mRNA]	25932594
C002791	bismuth tripotassium dicitrate	bismuth tripotassium dicitrate results in decreased expression of TGM2 mRNA	15912405
C002791	bismuth tripotassium dicitrate	bismuth tripotassium dicitrate results in increased expression of TGM2 mRNA	15912405
C006780	bisphenol A	bisphenol A results in decreased expression of TGM2 mRNA	29275510
C006780	bisphenol A	bisphenol A results in decreased methylation of TGM2 promoter	27312807
C006780	bisphenol A	[bisphenol A co-treated with Estradiol] results in decreased expression of TGM2 mRNA	26496021
C006780	bisphenol A	bisphenol A results in decreased expression of TGM2 protein	22649256
C006780	bisphenol A	bisphenol A results in increased expression of TGM2 mRNA	25181051
C006780	bisphenol A	bisphenol A inhibits the reaction [Triiodothyronine results in increased expression of TGM2 mRNA]	19228888
D019819	Budesonide	Budesonide results in increased expression of TGM2 protein	21885873
D002065	Buspirone	Buspirone results in decreased expression of TGM2 mRNA	24136188
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in increased expression of TGM2 mRNA	15336504
D002087	Butyrates	Butyrates inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Tretinoin results in increased expression of TGM2 mRNA]]	10910994
D002087	Butyrates	Butyrates results in increased expression of TGM2 mRNA	10910994
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of TGM2 mRNA	26314618
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of TGM2 mRNA	27339419
D002251	Carbon Tetrachloride	PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of TGM2 mRNA]	18038451
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of TGM2 mRNA	17708605
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of TGM2 protein	17708605
D002251	Carbon Tetrachloride	Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 mRNA]	17708605
D002251	Carbon Tetrachloride	Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 protein]	17708605
C010063	carbonyl sulfide	carbonyl sulfide results in increased expression of TGM2 mRNA	19395590
C109628	CD 2425	"[4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid co-treated with CD 2425] results in increased expression of TGM2 mRNA"	9516142
C109628	CD 2425	"[4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid co-treated with CD 2425] results in increased expression of TGM2 protein"	9516142
C109628	CD 2425	[Am 580 co-treated with CD 2425] results in increased activity of TGM2 protein	9516142
C109628	CD 2425	CD 2425 promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA]	9516142
C109628	CD 2425	[CD 437 co-treated with CD 2425] results in increased activity of TGM2 protein	9516142
C099555	CD 437	[CD 437 co-treated with CD 2425] results in increased activity of TGM2 protein	9516142
C098137	Ch 80	Ch 80 results in increased activity of TGM2 protein	2884032
D004390	Chlorpyrifos	Chlorpyrifos results in increased activity of TGM2 protein	20637855
D004390	Chlorpyrifos	Chlorpyrifos results in increased activity of TGM2 protein	20637855
C018021	cobaltous chloride	cobaltous chloride results in decreased expression of TGM2 mRNA	19320972\|1937684
C018021	cobaltous chloride	cobaltous chloride results in increased expression of TGM2 mRNA	23052192
C018021	cobaltous chloride	cobaltous chloride results in decreased expression of TGM2 mRNA	24386269
D003345	Corticosterone	Corticosterone results in increased expression of TGM2 mRNA	15755911
D003471	Cuprizone	Cuprizone results in increased expression of TGM2 mRNA	26577399
D003474	Curcumin	Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGM2 mRNA]	18200517
C057862	cyanoginosin LR	cyanoginosin LR results in increased expression of TGM2 mRNA	17654400
D016572	Cyclosporine	Cyclosporine results in decreased expression of TGM2 mRNA	19159671\|2010694
D016572	Cyclosporine	Cyclosporine results in increased expression of TGM2 mRNA	25562108
D016572	Cyclosporine	Cyclosporine results in decreased expression of TGM2 mRNA	19770486
D003538	Cystamine	Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 mRNA]	17708605
D003538	Cystamine	Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 protein]	17708605
C004742	daidzein	daidzein results in increased expression of TGM2 mRNA	24859791
C004742	daidzein	daidzein results in increased expression of TGM2 protein	24859791
C010902	decabromobiphenyl ether	decabromobiphenyl ether analog results in increased expression of TGM2 mRNA	26854739
D003907	Dexamethasone	apicidin inhibits the reaction [Dexamethasone results in increased expression of TGM2 mRNA]	23946490
D003907	Dexamethasone	Dexamethasone results in increased expression of TGM2 mRNA	23946490\|2922923
D003907	Dexamethasone	trichostatin A inhibits the reaction [Dexamethasone results in increased expression of TGM2 mRNA]	23946490
D003907	Dexamethasone	Valproic Acid inhibits the reaction [Dexamethasone results in increased expression of TGM2 mRNA]	23946490
C438269	diazepinylbenzoic acid	diazepinylbenzoic acid inhibits the reaction [bexarotene results in increased expression of TGM2 mRNA]	25932594
C438269	diazepinylbenzoic acid	diazepinylbenzoic acid inhibits the reaction [tributyltin results in increased expression of TGM2 mRNA]	25932594
C438269	diazepinylbenzoic acid	diazepinylbenzoic acid results in decreased expression of TGM2 mRNA	25932594
D003976	Diazinon	Diazinon results in increased methylation of TGM2 gene	22964155
D003976	Diazinon	Diazinon affects the expression of TGM2 mRNA	22546817
D002945	Cisplatin	[Hexylresorcinol results in decreased activity of TGM2 protein] which results in increased susceptibility to Cisplatin	21424127
D004026	Dieldrin	Dieldrin affects the expression of TGM2 mRNA	22546817
D004041	Dietary Fats	Dietary Fats results in increased expression of TGM2 mRNA	22609946
C014476	diethyl maleate	diethyl maleate results in increased expression of TGM2 mRNA	21161181
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of TGM2 mRNA	21527772
D002117	Calcitriol	Calcitriol results in increased expression of TGM2 mRNA	21592394\|2648566
D002117	Calcitriol	[Testosterone co-treated with Calcitriol] results in increased expression of TGM2 mRNA	21592394
D004121	Dimethyl Sulfoxide	[alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [HIST3H3 protein modified form binds to TGM2 gene]	15964820
D004121	Dimethyl Sulfoxide	[alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [HIST4H4 protein modified form binds to TGM2 gene]	15964820
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of TGM2 mRNA]	15964820
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of TGM2 protein]	15964820
D004121	Dimethyl Sulfoxide	periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of TGM2 mRNA]]	15964820
D004317	Doxorubicin	Doxorubicin results in increased expression of TGM2 mRNA	15870702
D004317	Doxorubicin	TGM2 protein affects the susceptibility to Doxorubicin	17073438
D052244	Endocrine Disruptors	Endocrine Disruptors results in increased expression of TGM2 mRNA	25198161
C118739	entinostat	entinostat results in increased expression of TGM2 mRNA	27188386
D000431	Ethanol	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	18295389
D000431	Ethanol	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	18295389
D000431	Ethanol	Ethanol promotes the reaction [RELA protein binds to TGM2 promoter]	18295389
D000431	Ethanol	Ethanol results in increased activity of TGM2 protein	18295389
D000431	Ethanol	Ethanol results in increased expression of TGM2 mRNA	18295389
D000431	Ethanol	pinocembrin inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	18295389
D000431	Ethanol	pinocembrin inhibits the reaction [Ethanol results in increased expression of TGM2 mRNA]	18295389
D000431	Ethanol	Propolis inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	18295389
D000431	Ethanol	Propolis inhibits the reaction [Ethanol results in increased expression of TGM2 mRNA]	18295389
D000431	Ethanol	Tosyllysine Chloromethyl Ketone inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	18295389
D000431	Ethanol	Tosyllysine Chloromethyl Ketone inhibits the reaction [Ethanol results in increased expression of TGM2 mRNA]	18295389
D000431	Ethanol	Ethanol results in increased activity of TGM2 protein	11696672
D000431	Ethanol	Ethanol results in increased expression of TGM2 mRNA	11696672
D000431	Ethanol	Ethanol inhibits the reaction [Phenylephrine results in decreased activity of TGM2 protein]	10801782
D000431	Ethanol	Ethanol results in increased activity of TGM2 protein	10801782
D000431	Ethanol	Ethanol results in increased expression of TGM2 mRNA	10801782
D000431	Ethanol	Putrescine inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	10801782
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of TGM2 mRNA	14976129\|1755557
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of TGM2 mRNA	17942748
D004997	Ethinyl Estradiol	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TGM2 mRNA	17942748
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of TGM2 mRNA	23300682
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of TGM2 mRNA	15834898\|1755790
C000499	ferric oxide	ferric oxide analog results in increased expression of TGM2 mRNA	25086211
D018120	Finasteride	Finasteride results in increased expression of TGM2 mRNA	24136188
C007734	flunisolide	flunisolide results in increased expression of TGM2 protein	21885873
C061365	flusilazole	flusilazole results in increased expression of TGM2 mRNA	28263823
D005485	Flutamide	Flutamide results in decreased expression of TGM2 mRNA	24136188
D005557	Formaldehyde	Formaldehyde results in decreased expression of TGM2 mRNA	28937961
C069837	fullerene C60	fullerene C60 results in decreased expression of TGM2 mRNA	19167457
D005839	Gentamicins	Gentamicins results in decreased expression of TGM2 mRNA	22061828
D006118	Griseofulvin	Griseofulvin affects the expression of TGM2 mRNA	12735108
D006160	Guanosine Triphosphate	Guanosine Triphosphate binds to TGM2 protein	15556610
C010176	halofuginone	halofuginone results in increased expression of TGM2 mRNA	17180598
D006427	Hemin	[Hemin co-treated with Tretinoin] affects the localization of TGM2 protein	15556610
D006533	Heptachlor	Heptachlor results in decreased expression of TGM2 mRNA	23153324
D006604	Hexylresorcinol	Hexylresorcinol results in decreased activity of and affects the localization of TGM2 protein	21424127
D006604	Hexylresorcinol	[Hexylresorcinol results in decreased activity of TGM2 protein] which results in increased susceptibility to Cisplatin	21424127
D017313	Fenretinide	Fenretinide results in increased expression of TGM2 mRNA	28973697
C029424	hydrazine	hydrazine results in increased expression of TGM2 mRNA	15282401
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TGM2 mRNA	25613284
D007545	Isoproterenol	Isoproterenol results in increased expression of TGM2 mRNA	20003209
D007555	Isoxazoles	Isoxazoles analog results in decreased activity of TGM2 protein	15850984
D007555	Isoxazoles	Isoxazoles analog results in decreased activity of TGM2 protein	15850984
C561695	(+)-JQ1 compound	[(+)-JQ1 compound co-treated with PD 0325901] results in decreased expression of TGM2 mRNA	25119042
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of TGM2 mRNA	24796395\|2511904
C510621	KCC 009	KCC 009 results in decreased activity of TGM2 protein	16170020
C510621	KCC 009	KCC 009 results in decreased activity of TGM2 protein	17099729
C510621	KCC 009	[KCC 009 results in decreased activity of TGM2 protein] which affects the localization of FN1 protein	17099729
C533894	LG 100815	LG 100815 results in increased expression of TGM2 mRNA	16951191
C482199	lipopolysaccharide, E coli O55-B5	"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TGM2 mRNA"	18930950
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of TGM2 mRNA	27339419
D058185	Magnetite Nanoparticles	[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TGM2 mRNA	21641980
D058185	Magnetite Nanoparticles	[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of TGM2 mRNA	26378955
D008731	Methoxychlor	Methoxychlor results in increased methylation of TGM2 gene	23303685
D016685	Mitomycin	TGM2 protein affects the susceptibility to Mitomycin	16217747
D000068656	Mometasone Furoate	Mometasone Furoate results in increased expression of TGM2 protein	21885873
C008542	monodansylcadaverine	monodansylcadaverine results in decreased activity of TGM2 protein	16382148
C008542	monodansylcadaverine	monodansylcadaverine results in decreased activity of TGM2 protein	16170020
C500085	muraglitazar	muraglitazar results in increased expression of TGM2 mRNA	21515302
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of TGM2 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of TGM2 mRNA"	25554681\|2562005
C031721	naphthalene	naphthalene metabolite binds to TGM2 protein	16453347
C031721	naphthalene	naphthalene analog results in decreased expression of TGM2 mRNA	24976557
C017096	n-butoxyethanol	n-butoxyethanol results in increased expression of TGM2 mRNA	19812364
C051752	nefazodone	nefazodone results in decreased expression of TGM2 mRNA	24136188
D009532	Nickel	Nickel results in increased expression of TGM2 mRNA	24768652\|2558310
C012655	nimesulide	nimesulide results in decreased expression of TGM2 mRNA	24136188
C062198	octa-2,4,6-trienoic acid	"octa-2,4,6-trienoic acid results in increased expression of TGM2 mRNA"	16951191
C510784	ormosil	[ormosil binds to Polyethylene Glycols] which results in increased expression of TGM2 mRNA	24888373
C016030	pantogab	pantogab results in increased expression of TGM2 mRNA	17379144
D052638	Particulate Matter	[Particulate Matter co-treated with IL4 protein] results in increased expression of TGM2 mRNA	27224998
D052638	Particulate Matter	Acetylcysteine inhibits the reaction [Particulate Matter analog results in decreased activity of TGM2 protein]	15541757
D052638	Particulate Matter	Particulate Matter analog results in decreased activity of TGM2 protein	15541757
D052638	Particulate Matter	Particulate Matter analog results in decreased expression of TGM2 mRNA	15541757
C506614	PD 0325901	[(+)-JQ1 compound co-treated with PD 0325901] results in decreased expression of TGM2 mRNA	25119042
C506614	PD 0325901	PD 0325901 results in decreased expression of TGM2 mRNA	25119042
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in increased expression of TGM2 mRNA	23948077
C101814	perfluoro-n-undecanoic acid	perfluoro-n-undecanoic acid results in decreased expression of TGM2 mRNA	23602845
C027579	periodate-oxidized adenosine	periodate-oxidized adenosine inhibits the reaction [alitretinoin results in increased expression of TGM2 mRNA]	15964820
C027579	periodate-oxidized adenosine	periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of TGM2 mRNA]]	15964820
D010634	Phenobarbital	NR1I3 protein affects the reaction [Phenobarbital results in increased expression of TGM2 mRNA]	19482888
D010634	Phenobarbital	Phenobarbital results in increased expression of TGM2 mRNA	19482888
D010656	Phenylephrine	ADRA1B protein affects the reaction [Phenylephrine results in decreased activity of TGM2 protein]	10801782
D010656	Phenylephrine	Ethanol inhibits the reaction [Phenylephrine results in decreased activity of TGM2 protein]	10801782
D010656	Phenylephrine	Phenylephrine results in decreased activity of TGM2 protein	10801782
D010656	Phenylephrine	Phenylephrine results in increased expression of TGM2 mRNA	18158353
C046357	phenylsaligenin cyclic phosphate	phenylsaligenin cyclic phosphate affects the activity of TGM2 protein	19735718
C046357	phenylsaligenin cyclic phosphate	phenylsaligenin cyclic phosphate results in increased expression of TGM2 protein	19735718
C046357	phenylsaligenin cyclic phosphate	phenylsaligenin cyclic phosphate results in decreased activity of TGM2 protein	19735718
C046357	phenylsaligenin cyclic phosphate	phenylsaligenin cyclic phosphate results in decreased expression of TGM2 protein	19735718
D010798	Phycocyanin	Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TGM2 mRNA]	22986104
D010798	Phycocyanin	Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TGM2 protein]	22986104
C016063	pinocembrin	pinocembrin inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	18295389
C016063	pinocembrin	pinocembrin inhibits the reaction [Ethanol results in increased expression of TGM2 mRNA]	18295389
C006253	pirinixic acid	pirinixic acid results in increased expression of TGM2 mRNA	18301758\|1844570
D010894	Piroxicam	Piroxicam results in decreased expression of TGM2 mRNA	21858171
D010938	Plant Oils	Plant Oils results in decreased expression of TGM2 mRNA	23370395
D028321	Plant Preparations	Plant Preparations affects the expression of TGM2 mRNA	16251609
D011078	Polychlorinated Biphenyls	Polychlorinated Biphenyls affects the expression of TGM2 mRNA	21334430
D011092	Polyethylene Glycols	[ormosil binds to Polyethylene Glycols] which results in increased expression of TGM2 mRNA	24888373
C027373	potassium chromate(VI)	potassium chromate(VI) results in increased expression of TGM2 mRNA	22714537
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of TGM2 mRNA	28903501
D011374	Progesterone	[Progesterone co-treated with Estradiol] results in decreased expression of TGM2 mRNA	17404688
D011374	Progesterone	Progesterone results in increased expression of TGM2 mRNA	21540246
D011374	Progesterone	Progesterone results in increased expression of TGM2 mRNA	20726854
C045950	propiconazole	propiconazole results in increased expression of TGM2 mRNA	21278054
D011429	Propolis	Propolis inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	18295389
D011429	Propolis	Propolis inhibits the reaction [Ethanol results in increased expression of TGM2 mRNA]	18295389
D011700	Putrescine	Putrescine inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	10801782
C513428	pyrachlostrobin	pyrachlostrobin results in increased expression of TGM2 mRNA	27029645
D011794	Quercetin	Quercetin binds to and results in decreased activity of TGM2 protein	23117658
D011794	Quercetin	[TGM2 protein affects the susceptibility to Warfarin] which affects the susceptibility to Quercetin	23117658
D011794	Quercetin	Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of and results in increased activity of TGM2 protein]	23117658
D011794	Quercetin	Quercetin inhibits the reaction [Warfarin results in increased activity of TGM2 protein]	23117658
C012526	quercitrin	quercitrin results in decreased expression of TGM2 mRNA	25193878
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride affects the expression of TGM2 mRNA	14699072
D012176	Retinoids	RARA protein promotes the reaction [Retinoids results in increased expression of TGM2 mRNA]	12075115
D012176	Retinoids	Retinoids results in increased expression of TGM2 mRNA	12075115
C089730	rosiglitazone	rosiglitazone results in increased expression of TGM2 mRNA	16982809
C089730	rosiglitazone	rosiglitazone results in increased expression of TGM2 mRNA	21515302
D012822	Silicon Dioxide	Silicon Dioxide analog results in increased expression of TGM2 mRNA	25895662
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of TGM2 mRNA	25351596
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of TGM2 mRNA	23221170
D012834	Silver	Silver results in increased expression of TGM2 mRNA	28959546
D020123	Sirolimus	Sirolimus results in decreased expression of TGM2 mRNA	11355896
D012999	Soman	Soman results in increased expression of TGM2 mRNA	19281266
D053260	Soot	Soot results in increased expression of TGM2 mRNA	26551751
D004113	Succimer	[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TGM2 mRNA	21641980
D004113	Succimer	[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of TGM2 mRNA	26378955
D013467	Sulindac	Sulindac inhibits the reaction [CDKN1A protein results in increased expression of TGM2 mRNA]	15190207
D014284	Triiodothyronine	bisphenol A inhibits the reaction [Triiodothyronine results in increased expression of TGM2 mRNA]	19228888
D014284	Triiodothyronine	Triiodothyronine results in increased expression of TGM2 mRNA	19228888
C061133	tamibarotene	tamibarotene results in increased activity of TGM2 protein	2884032
D013629	Tamoxifen	Tamoxifen affects the expression of TGM2 mRNA	14699072
D013629	Tamoxifen	Tamoxifen affects the expression of TGM2 mRNA	17555576
C031655	tauroursodeoxycholic acid	tauroursodeoxycholic acid results in decreased expression of TGM2 mRNA	15885361
C501413	tesaglitazar	tesaglitazar results in increased expression of TGM2 mRNA	21515302
D013739	Testosterone	[Testosterone co-treated with Calcitriol] results in increased expression of TGM2 mRNA	21592394
D013739	Testosterone	Testosterone results in increased expression of TGM2 mRNA	21592394
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of TGM2 mRNA	26854739
D013749	Tetrachlorodibenzodioxin	7-ketocholesterol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TGM2 mRNA]	16480812
D013749	Tetrachlorodibenzodioxin	Butyrates inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Tretinoin results in increased expression of TGM2 mRNA]]	10910994
D013749	Tetrachlorodibenzodioxin	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of TGM2 mRNA	19619570
D013749	Tetrachlorodibenzodioxin	"Tetrachlorodibenzodioxin inhibits the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of TGM2 mRNA]"	10910994
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin inhibits the reaction [Tretinoin results in increased expression of TGM2 mRNA]	10910994\|1207511
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of TGM2 mRNA	19619570
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of TGM2 mRNA	16480812
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of TGM2 mRNA	19770486\|2157046
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TGM2 mRNA	17942748
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of TGM2 mRNA	15652763
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of TGM2 mRNA	27562557
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of TGM2 mRNA	21215274
C582340	tetradecabromodiphenoxybenzene	tetradecabromodiphenoxybenzene analog results in increased expression of TGM2 mRNA	26854739
D013755	Tetradecanoylphorbol Acetate	Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TGM2 mRNA]	22986104
D013755	Tetradecanoylphorbol Acetate	Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TGM2 protein]	22986104
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in decreased expression of TGM2 mRNA	22986104
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in decreased expression of TGM2 protein	22986104
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TGM2 mRNA	25613284
D019284	Thapsigargin	Thapsigargin results in increased expression of and results in increased activity of TGM2 protein	16382148
D013876	Thiophenes	Thiophenes analog promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA]	16140955
C009495	titanium dioxide	titanium dioxide affects the expression of TGM2 mRNA	17656681
C009495	titanium dioxide	titanium dioxide results in increased expression of TGM2 mRNA	27760801
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in decreased expression of TGM2 mRNA	25447457\|2806579
C024746	tobacco tar	tobacco tar results in decreased expression of TGM2 mRNA	19559774
D014050	Toluene	Toluene results in increased expression of TGM2 mRNA	22967744
D019772	Topotecan	TGM2 protein affects the susceptibility to Topotecan	16217747
D014107	Tosyllysine Chloromethyl Ketone	Tosyllysine Chloromethyl Ketone inhibits the reaction [Ethanol results in increased activity of TGM2 protein]	18295389
D014107	Tosyllysine Chloromethyl Ketone	Tosyllysine Chloromethyl Ketone inhibits the reaction [Ethanol results in increased expression of TGM2 mRNA]	18295389
D014118	Toxins, Biological	"Toxins, Biological affects the expression of TGM2 mRNA"	19682533
D014212	Tretinoin	"4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid inhibits the reaction [Tretinoin results in increased expression of TGM2 mRNA]"	9516142
D014212	Tretinoin	AGN 193109 inhibits the reaction [Tretinoin results in increased expression of TGM2 protein]	16158052
D014212	Tretinoin	arsenic trioxide inhibits the reaction [Tretinoin results in increased expression of TGM2 protein]	11133770\|9450572
D014212	Tretinoin	Butyrates inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Tretinoin results in increased expression of TGM2 mRNA]]	10910994
D014212	Tretinoin	CD 2425 promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA]	9516142
D014212	Tretinoin	[Hemin co-treated with Tretinoin] affects the localization of TGM2 protein	15556610
D014212	Tretinoin	Tetrachlorodibenzodioxin inhibits the reaction [Tretinoin results in increased expression of TGM2 mRNA]	10910994\|1207511
D014212	Tretinoin	Thiophenes analog promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA]	16140955
D014212	Tretinoin	Tretinoin results in increased activity of TGM2 protein	2884032\|9516142
D014212	Tretinoin	Tretinoin results in increased expression of and results in increased activity of TGM2 protein	16158929
D014212	Tretinoin	Tretinoin results in increased expression of TGM2 mRNA	10910994\|1207511
D014212	Tretinoin	Tretinoin results in increased expression of TGM2 protein	11133770\|1615805
D014212	Tretinoin	Tretinoin results in increased expression of TGM2 mRNA	16505366\|1660451
D014212	Tretinoin	Tretinoin results in increased expression of TGM2 mRNA	20488242
D014212	Tretinoin	Tretinoin results in increased expression of TGM2 mRNA	28689802
C011559	tributyltin	diazepinylbenzoic acid inhibits the reaction [tributyltin results in increased expression of TGM2 mRNA]	25932594
C011559	tributyltin	tributyltin results in increased expression of TGM2 mRNA	21622945\|2593259
D014241	Trichloroethylene	Trichloroethylene results in increased methylation of TGM2 gene	27618143
C012589	trichostatin A	trichostatin A results in increased expression of TGM2 mRNA	26705709
C012589	trichostatin A	trichostatin A inhibits the reaction [Dexamethasone results in increased expression of TGM2 mRNA]	23946490
C012589	trichostatin A	trichostatin A results in decreased expression of TGM2 mRNA	15901671
D014302	Trinitrobenzenesulfonic Acid	Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGM2 mRNA]	18200517
D014302	Trinitrobenzenesulfonic Acid	Trinitrobenzenesulfonic Acid results in increased expression of TGM2 mRNA	18200517
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate affects the expression of TGM2 mRNA"	26179874
C013320	tris(2-butoxyethyl) phosphate	tris(2-butoxyethyl) phosphate affects the expression of TGM2 mRNA	29024780
C057693	troglitazone	troglitazone results in decreased expression of TGM2 mRNA	21515302
C080163	trovafloxacin	"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TGM2 mRNA"	18930950
C022884	undecane	undecane results in increased expression of TGM2 protein	17337753
D014580	Ursodeoxycholic Acid	Ursodeoxycholic Acid results in decreased expression of TGM2 mRNA	15885361
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TGM2 mRNA"	27188386
D014635	Valproic Acid	Valproic Acid affects the expression of TGM2 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in decreased methylation of TGM2 gene	29154799
D014635	Valproic Acid	Valproic Acid results in increased expression of TGM2 mRNA	23179753\|2627250
D014635	Valproic Acid	Valproic Acid inhibits the reaction [Dexamethasone results in increased expression of TGM2 mRNA]	23946490
D014635	Valproic Acid	Valproic Acid results in decreased expression of TGM2 mRNA	15901671
D014640	Vancomycin	Vancomycin results in decreased expression of TGM2 mRNA	18930951
D001335	Vehicle Emissions	Vehicle Emissions analog inhibits the reaction [IL4 protein results in increased expression of TGM2 mRNA]	27224998
D001335	Vehicle Emissions	[Vehicle Emissions co-treated with IL4 protein] results in increased expression of TGM2 mRNA	27224998
D001335	Vehicle Emissions	Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in decreased activity of TGM2 protein]	15541757
D001335	Vehicle Emissions	Vehicle Emissions analog results in decreased activity of TGM2 protein	15541757
D001335	Vehicle Emissions	Vehicle Emissions analog results in decreased expression of TGM2 mRNA	15541757
C025643	vinclozolin	vinclozolin affects the expression of TGM2 mRNA	19015723
C029297	vinylidene chloride	vinylidene chloride results in increased expression of TGM2 mRNA	26682919
D014801	Vitamin A	Vitamin A results in increased expression of TGM2 mRNA	17034753
D014801	Vitamin A	Vitamin A affects the expression of TGM2 mRNA	14529804
D014807	Vitamin D	Vitamin D promotes the reaction [alitretinoin results in increased expression of TGM2 mRNA]	15964820
D014812	Vitamin K	Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of and results in increased activity of TGM2 protein]	23117658
D014812	Vitamin K	[Warfarin co-treated with Vitamin K] results in increased expression of and results in increased activity of TGM2 protein	23117658
D014859	Warfarin	TGM2 protein affects the susceptibility to Warfarin	23117658
D014859	Warfarin	[TGM2 protein affects the susceptibility to Warfarin] which affects the susceptibility to Quercetin	23117658
D014859	Warfarin	TGM2 protein results in increased susceptibility to Warfarin	23117658
D014859	Warfarin	Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of and results in increased activity of TGM2 protein]	23117658
D014859	Warfarin	Quercetin inhibits the reaction [Warfarin results in increased activity of TGM2 protein]	23117658
D014859	Warfarin	[Warfarin co-treated with Vitamin K] results in increased expression of and results in increased activity of TGM2 protein	23117658
D014859	Warfarin	Warfarin results in increased expression of and results in increased activity of TGM2 protein	23117658
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical results in increased expression of TGM2 mRNA"	25198161
D015032	Zinc	Zinc deficiency results in decreased expression of TGM2 mRNA	16140947
D015032	Zinc	Zinc inhibits the reaction [Zinc deficiency results in decreased expression of TGM2 mRNA]	16140947
C088658	zoledronic acid	zoledronic acid results in increased expression of TGM2 mRNA	24714768

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0003810	protein-glutamine gamma-glutamyltransferase activity	-	IMP	24349085
GO:0003810	protein-glutamine gamma-glutamyltransferase activity	-	ISS	-
GO:0005515	protein binding	-	IPI	9442029 14517264 16301118 16951195 19542224 19738201 20080707 21625219 22442151 28106549
GO:0005525	GTP binding	-	IEA	-
GO:0019904	protein domain specific binding	-	IEA	-
GO:0046872	metal ion binding	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001974	blood vessel remodeling	-	IEA	-
GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	-	IEA	-
GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration	-	IMP	24349085
GO:0043065	positive regulation of apoptotic process	-	IMP	24349085
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	-	IEA	-
GO:0043277	apoptotic cell clearance	-	IDA	19628791
GO:0045785	positive regulation of cell adhesion	-	ISS	-
GO:0048661	positive regulation of smooth muscle cell proliferation	-	IEA	-
GO:0050729	positive regulation of inflammatory response	-	IEA	-
GO:0051260	protein homooligomerization	-	IEA	-
GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway	-	IEA	-
GO:0051561	positive regulation of mitochondrial calcium ion concentration	-	IMP	24349085
GO:0060445	branching involved in salivary gland morphogenesis	-	IEA	-
GO:0060662	salivary gland cavitation	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005739	mitochondrion	-	IDA	24349085
GO:0005783	endoplasmic reticulum	-	IEA	-
GO:0005829	cytosol	-	IDA	24349085
GO:0005925	focal adhesion	-	HDA	21423176
GO:0031226	intrinsic component of plasma membrane	-	IDA	2578891
GO:0031226	intrinsic component of plasma membrane	-	IMP	8105889
GO:0062023	collagen-containing extracellular matrix	-	HDA	23979707
GO:0070062	extracellular exosome	-	HDA	19056867 23533145

KEGG ID	KEGG Term
hsa05016	Huntington's disease

Reactome ID	Reactome Term	Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
27084846	Lung tissue proteomics identifies elevated transglutaminase 2 levels in stable chronic obstructive pulmonary disease. (2016 Jun 1)	Ohlmeier S	Am J Physiol Lung Cell Mol Physiol