Gene: TIMP1

7076
CLGI|EPA|EPO|HCI|TIMP|TIMP-1
TIMP metallopeptidase inhibitor 1
protein-coding
Xp11.3
Ensembl:ENSG00000102265 MIM:305370 Vega:OTTHUMG00000021447 UniprotKB:P01033
NG_012533.1
PubMed
ND
9   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ANXA20.887
PLP20.884
CLIC10.882
EMP30.879
TAGLN20.879
MYD880.874
LTBR0.868
S100A110.868
IFITM30.866
RAB130.866

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NEUROD6-0.655
MARCH4-0.622
SLC7A4-0.617
ABCC12-0.613
CALHM1-0.603
KCNQ4-0.601
F7-0.598
PPEF1-0.592
VWC2-0.587
NDST3-0.581

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of TIMP1 mRNA"22579512
C5815721-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea results in decreased expression of TIMP1 mRNA25827057
C0058492,2,2-trichloroethanol"2,2,2-trichloroethanol results in increased expression of TIMP1 mRNA"21741468
C0058492,2,2-trichloroethanol"2,2,2-trichloroethanol results in increased expression of TIMP1 protein"21741468
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of TIMP1 mRNA"21394737
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of TIMP1 mRNA10866818
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein]]"27274199
C0630022,3-dimethoxy-1,4-naphthoquinone"2,3-dimethoxy-1,4-naphthoquinone results in increased expression of TIMP1 mRNA"17547211
C0131862,3-pentanedione"2,3-pentanedione results in increased expression of TIMP1 mRNA"25710175
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein]19561517
C55788225-methoxyldammarane-3,12,20-triol"25-methoxyldammarane-3,12,20-triol inhibits the reaction [TNF protein results in increased expression of TIMP1 protein]"21924252
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in decreased expression of TIMP1 mRNA"12097258
C4574992-chloro-5-nitrobenzanilide2-chloro-5-nitrobenzanilide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein]28416457
C5188602-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]"26443840
C5779422-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide"2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide results in decreased expression of TIMP1 mRNA"26644586
C0194992-nitrofluorene2-nitrofluorene results in increased expression of TIMP1 mRNA14600272|1589037
C5029712-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]15723089
C560356(2S,4R)-methyl-1-acetyl-4-(N-(4-bromophenyl)sulfamoyloxy)pyrrolidine-2-carboxylate"(2S,4R)-methyl-1-acetyl-4-(N-(4-bromophenyl)sulfamoyloxy)pyrrolidine-2-carboxylate results in decreased expression of TIMP1 protein"21349324
C0163923,3'-diindolylmethane"3,3'-diindolylmethane analog results in increased expression of TIMP1 protein"25794856
C4778983-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of TIMP1 protein]25822713
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA"28973532
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]"28163111
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TIMP1 mRNA"28163111
C0005949583,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide"3,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide inhibits the reaction [IL1B protein results in decreased expression of TIMP1 mRNA]"26107568
C0005949583,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide"3,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide inhibits the reaction [IL1B protein results in decreased secretion of TIMP1 protein]"26107568
C0144643,4-dichloroaniline"3,4-dichloroaniline results in increased expression of TIMP1 mRNA"24172598
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of TIMP1 mRNA"18289764
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of TIMP1 mRNA"25380136
C4086904-cresol sulfate4-cresol sulfate results in increased expression of TIMP1 mRNA23325087
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of TIMP1 mRNA14672615
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of TIMP1 mRNA19191707
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TIMP1 mRNA14600272|1589037
C0920067-Ala-angiotensin (1-7)7-Ala-angiotensin (1-7) inhibits the reaction [AGT protein modified form results in decreased expression of TIMP1 mRNA]20837116
C0920067-Ala-angiotensin (1-7)7-Ala-angiotensin (1-7) results in increased expression of TIMP1 mRNA20837116
C5700198-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide"8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]"22063920
C5700198-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide"8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide results in decreased expression of TIMP1 protein"22063920
C099958acanthoic acidacanthoic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]24802811
C099958acanthoic acidacanthoic acid inhibits the reaction [Ethanol results in increased expression of TIMP1 mRNA]28964808
C099958acanthoic acidacanthoic acid inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]28964808
D000082AcetaminophenAcetaminophen results in increased expression of TIMP1 mRNA22230336
D000082AcetaminophenAcetaminophen affects the expression of TIMP1 mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of TIMP1 mRNA28286204
D000082AcetaminophenEGR1 protein affects the reaction [Acetaminophen results in increased expression of TIMP1 mRNA]28286204
D000082AcetaminophenAcetaminophen results in increased expression of TIMP1 protein16687475
D020106AcrylamideAcrylamide results in decreased expression of TIMP1 protein16876394
D000255Adenosine TriphosphateAdenosine Triphosphate results in decreased secretion of TIMP1 protein26522449
D000255Adenosine Triphosphateazetidine analog inhibits the reaction [Adenosine Triphosphate results in decreased secretion of TIMP1 protein]26522449
D016604Aflatoxin B1Aflatoxin B1 affects the expression of TIMP1 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of TIMP1 mRNA21632981|2164198
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of TIMP1 mRNA14600272|1589037
C031143AICA ribonucleotideAICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 protein]27688165
C000188alachloralachlor results in increased expression of TIMP1 mRNA12419858
D019386AlendronateAlendronate affects the expression of TIMP1 mRNA16079270
C006463allyl alcoholallyl alcohol results in increased expression of TIMP1 mRNA23558518
C103505AM 251AM 251 inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
C103505AM 251AM 251 inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C103505AM 251[iodopravadoline co-treated with AM 251] inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
C103505AM 251[iodopravadoline co-treated with AM 251] inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
D006710HomocysteineDizocilpine Maleate inhibits the reaction [Homocysteine analog results in increased expression of TIMP1 mRNA]20406136
D006710HomocysteineDizocilpine Maleate inhibits the reaction [Homocysteine analog results in increased expression of TIMP1 protein]20406136
D006710HomocysteineHomocysteine analog results in increased expression of TIMP1 mRNA20406136
D006710HomocysteineHomocysteine analog results in increased expression of TIMP1 protein20406136
D000499AllylamineAllylamine results in increased expression of TIMP1 mRNA23558518
D000643Ammonium ChlorideAmmonium Chloride affects the expression of TIMP1 mRNA16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of TIMP1 mRNA"22863853
D000667AmpicillinAmpicillin results in decreased expression of TIMP1 mRNA21632981
C078814anandamideanandamide results in increased expression of TIMP1 mRNA16330497
C078814anandamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of TIMP1 mRNA]16330497
C006578anetholeanethole results in increased expression of TIMP1 mRNA21212515
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of TIMP1 mRNA24449571
D016718Arachidonic AcidCYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA]16581302
D016718Arachidonic Acid[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA16581302
C015688arecaidinearecaidine results in increased expression of TIMP1 mRNA16311067
C015688arecaidinearecaidine results in increased expression of TIMP1 protein16311067
D001115ArecolineArecoline results in increased expression of TIMP1 mRNA16311067
D001115ArecolineArecoline results in increased expression of TIMP1 protein16311067
C031942argatrobanargatroban inhibits the reaction [Dietary Fats results in increased expression of TIMP1 mRNA]22841818
C047981arginyl-glycyl-aspartic acidarginyl-glycyl-aspartic acid results in decreased expression of TIMP115547672
C026987aroclor 1260[Methionine deficiency co-treated with Choline deficiency co-treated with aroclor 1260] results in increased expression of TIMP1 mRNA28163111
C025657arsenic acidarsenic acid results in increased expression of TIMP1 mRNA18296743
C025657arsenic acidDietary Fats promotes the reaction [arsenic acid results in increased expression of TIMP1 mRNA]18296743
C006632arsenic trioxidearsenic trioxide results in increased expression of TIMP1 mRNA15962302|1662439
C006632arsenic trioxidearsenic trioxide results in increased expression of TIMP1 protein15962302|1662439
C015001arseniteDietary Fats promotes the reaction [arsenite results in increased expression of TIMP1 mRNA]18296743
C015001arsenitearsenite results in increased expression of TIMP1 mRNA18296743
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of TIMP1"16574944
D001205Ascorbic Acid[Ascorbic Acid co-treated with Quartz] results in increased expression of TIMP1 mRNA27381660
D001205Ascorbic AcidAscorbic Acid results in increased expression of TIMP1 protein12510807
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [AGT protein modified form results in increased expression of TIMP1 protein]20881940
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TIMP1 protein]20881940
D001205Ascorbic AcidAscorbic Acid results in increased expression of TIMP1 mRNA15372504
D001241AspirinAspirin results in increased expression of TIMP1 mRNA18971601
D001241AspirinAspirin results in increased expression of TIMP1 mRNA19462226
D001241AspirinAspirin results in increased secretion of TIMP1 protein19462226
C040896AST 120AST 120 results in decreased expression of TIMP1 protein11867951
D006051Aurothioglucose[Dietary Fats co-treated with Aurothioglucose] results in increased expression of TIMP1 protein21382165
D001374AzacitidineAzacitidine results in increased expression of TIMP1 mRNA20823114
C406592azaspiracidazaspiracid results in increased expression of TIMP1 protein26865666
D001379AzathioprineAzathioprine results in increased expression of TIMP1 mRNA22623647
C082735azetidineazetidine analog inhibits the reaction [Adenosine Triphosphate results in decreased secretion of TIMP1 protein]26522449
C547126AZM551248AZM551248 results in increased expression of TIMP1 mRNA22323515
D001414BacitracinBacitracin results in increased expression of TIMP1 mRNA18289764
D001507BeclomethasoneBeclomethasone results in increased expression of TIMP1 protein10452757
C044946benazeprilbenazepril inhibits the reaction [Doxorubicin results in increased expression of TIMP1 mRNA]19357873
C044946benazeprilbenazepril inhibits the reaction [Doxorubicin results in increased expression of TIMP1 protein]19357873
C044946benazeprilbenazepril results in decreased expression of TIMP1 mRNA18471418
C044946benazeprilbenazepril results in decreased expression of TIMP1 protein11867951
D001542BenomylBenomyl results in increased expression of TIMP1 mRNA25530041
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of TIMP1 mRNA22579512
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TIMP1 mRNA18164116|2004503
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased expression of TIMP1 mRNA22579512
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TIMP1 mRNA20106945|2163298
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TIMP1 mRNA22228805
D004958Estradiol[Estradiol co-treated with EGF protein] results in increased expression of TIMP1 mRNA24758408
D004958EstradiolEstradiol results in decreased expression of TIMP1 mRNA16202921
D004958EstradiolEstradiol results in increased expression of TIMP1 mRNA20106945|2163298
D004958Estradiol[Progesterone co-treated with Estradiol] results in increased expression of TIMP1 mRNA20226447
D004958EstradiolEstradiol results in increased expression of TIMP1 mRNA19484750
C002503betulinbetulin inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]21172400
C002070betulinic acidbetulinic acid inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]21172400
C002070betulinic acidbetulinic acid inhibits the reaction [TNF protein results in increased expression of TIMP1 protein]22285267
D001629BezafibrateBezafibrate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA]18513333
C477843bicyclolbicyclol inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]16603200
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TIMP1 mRNA28628672
C006780bisphenol Abisphenol A affects the expression of TIMP1 mRNA25181051
D001761BleomycinBleomycin results in increased expression of TIMP1 mRNA26345256
D001761BleomycinBleomycin results in increased expression of TIMP1 protein28300665
D001761BleomycinDexamethasone inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]28300665
D001761BleomycinGrape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]28300665
D001786Blood Glucose"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein]]"27274199
D001786Blood Glucose[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein27274199
D001786Blood Glucoseursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein]27274199
D001966BromineBromine results in increased expression of TIMP1 mRNA21391292
C032036bromobenzenebromobenzene results in increased expression of TIMP1 mRNA12628495|1505680
D019819Budesonide"Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TIMP1 mRNA]"15734790
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of TIMP1 mRNA26472689
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TIMP1 mRNA25993096
D019256Cadmium ChlorideCadmium Chloride results in increased secretion of TIMP1 protein26815315
C037123cadmium sulfatecadmium sulfate affects the reaction [MTF1 affects the expression of TIMP1 mRNA]16221973
D002122Calcium ChlorideCalcium Chloride results in decreased expression of TIMP1 mRNA22728078
D002122Calcium ChlorideQuercetin inhibits the reaction [Calcium Chloride results in decreased expression of TIMP1 mRNA]22728078
D002185CannabidiolCannabidiol results in increased expression of TIMP1 mRNA22198381
D002185CannabidiolCannabidiol results in increased expression of TIMP1 protein22198381
D002185CannabidiolICAM1 mutant form inhibits the reaction [Cannabidiol results in increased expression of TIMP1 protein]22198381
D002211CapsaicinCapsaicin results in increased expression of TIMP1 mRNA21310942
D002211CapsaicinCapsaicin results in increased expression of TIMP1 protein22150557
D002211Capsaicin[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]22150557
D002211CapsaicinNaproxen inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]22150557
D002211CapsaicinSumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]22150557
C071423capsazepinecapsazepine inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C006698carbendazimcarbendazim results in increased expression of TIMP1 mRNA25530041
D002235CarbofuranCarbofuran results in increased expression of TIMP1 mRNA20211217
D002251Carbon Tetrachloride"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]"26443840
D002251Carbon Tetrachlorideacanthoic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]24802811
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of TIMP1 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of TIMP1 mRNA25827057
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of TIMP1 mRNA14999682|1505680
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of TIMP1 protein16508911|1653984
D002251Carbon TetrachlorideCCL2 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17125873
D002251Carbon Tetrachloride[Chlordecone co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA26853152
D002251Carbon TetrachlorideDinoprostone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]]25432964
D002251Carbon Tetrachlorideepigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]20438794
D002251Carbon TetrachlorideIL10 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]16539848
D002251Carbon TetrachlorideIL10 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]16539848
D002251Carbon Tetrachloride(+)-JQ1 compound inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]26644586
D002251Carbon TetrachlorideJUND gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17133482
D002251Carbon TetrachlorideMGAT5 protein affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]23798564
D002251Carbon TetrachlorideMMP9 protein mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]16507762
D002251Carbon TetrachlorideOleanolic Acid analog inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17922224
D002251Carbon TetrachlorideOSMR protein affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]14999682
D002251Carbon TetrachloridePLAT protein affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]17944888
D002251Carbon TetrachloridePOMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]16508911
D002251Carbon TetrachloridePOMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]16508911
D002251Carbon TetrachloridePTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]25432964
D002251Carbon TetrachlorideRDH13 protein promotes the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]27865848
D002251Carbon TetrachlorideRDH13 protein promotes the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]27865848
D002251Carbon TetrachlorideS1PR2 protein affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17341687
D002251Carbon TetrachlorideSC 560 inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]25432964
D002251Carbon Tetrachloride[Tetrachlorodibenzodioxin co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA27693115
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of TIMP1 mRNA16239168
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of TIMP1 mRNA11903743|1244542
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of TIMP1 protein15633229|1586057
D002251Carbon TetrachlorideCTGF affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]16652398
D002251Carbon TetrachlorideCYGB protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]16581302
D002251Carbon TetrachlorideCystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17708605
D002251Carbon Tetrachlorideebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]11903743
D002251Carbon TetrachlorideFR 167653 inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]17334410
D002251Carbon TetrachlorideIL10 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]15793858|1825116
D002251Carbon TetrachlorideIL10 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]16552806|1825116
D002251Carbon TetrachlorideInterleukin 1 Receptor Antagonist Protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]16762003
D002251Carbon TetrachlorideInterleukin 1 Receptor Antagonist Protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]16762003
D002251Carbon Tetrachlorideobeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]15860571
D002251Carbon Tetrachlorideoxymatrine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]15633229
D002251Carbon Tetrachloridepioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]16484506
D002251Carbon Tetrachloridepirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]12445421
D002251Carbon TetrachloridePlant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17157831
D002251Carbon Tetrachloridepuerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]23500774
D002251Carbon Tetrachloride[Quercetin co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA22989100
D002251Carbon TetrachlorideSulfasalazine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]15633128
D002251Carbon TetrachlorideThalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17030452
D002251Carbon TetrachlorideThalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]17030452
C524865carfilzomibcarfilzomib inhibits the reaction [Diethylnitrosamine results in increased expression of TIMP1 protein]24632418
D002331CarnitineCarnitine inhibits the reaction [sunitinib results in increased expression of TIMP1 mRNA]26581635
C043211carvedilolcarvedilol inhibits the reaction [Ethanol results in increased expression of TIMP1 mRNA]22413959
C043211carvedilolcarvedilol inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]22413959
C043211carvedilolcarvedilol results in decreased expression of TIMP1 mRNA21216836
D002509CephaloridineCephaloridine results in increased expression of TIMP1 mRNA18500788
D007631Chlordecone[Chlordecone co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA26853152
D002713Chlorine[Ozone co-treated with Chlorine] results in decreased expression of TIMP1 mRNA18636392
D002725ChloroformChloroform results in increased expression of TIMP1 mRNA17522070|2355851
C100187chloropicrinchloropicrin results in increased expression of TIMP1 mRNA26352163
D008078Cholesterol, LDL"Cholesterol, LDL metabolite results in increased expression of TIMP1 mRNA"11414687
D008078Cholesterol, LDL"Quercetin promotes the reaction [Cholesterol, LDL results in increased expression of TIMP1 mRNA]"11414687
D002794Choline"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA"28973532
D002794Choline"3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]"28163111
D002794CholineBezafibrate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA]18513333
D002794Choline[Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TIMP1 mRNA23439872
D002794Choline[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA18513333
D002794CholineFenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]19593819
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with aroclor 1260] results in increased expression of TIMP1 mRNA28163111
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TIMP1 mRNA20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA19593819|2069737
D002794CholineNR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]]19593819
D002794Cholinepirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]19593819
D002794CholineQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]22915297
D002857ChromiumChromium results in increased expression of TIMP1 mRNA15878362
D002857ChromiumChromium results in increased expression of TIMP1 protein16581223
D002857ChromiumGenistein inhibits the reaction [Chromium results in increased expression of TIMP1 mRNA]15878362
C031180chrysenechrysene results in increased expression of TIMP1 mRNA22579512
C418118CI 1044CI 1044 results in increased expression of TIMP1 mRNA17569694
C418118CI 1044CI 1044 results in increased expression of TIMP1 protein17569694
D004002Clodronic AcidClodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TIMP1 mRNA]27022031
D060729Coal AshCoal Ash results in decreased expression of TIMP1 mRNA19000753
D060729Coal AshCoal Ash results in increased expression of TIMP1 mRNA11114790
D003035CobaltCobalt results in increased expression of TIMP1 mRNA15878362
D003035CobaltGenistein inhibits the reaction [Cobalt results in increased expression of TIMP1 mRNA]15878362
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [ALB protein results in increased expression of TIMP1 protein]21163135
D003078ColchicineColchicine results in increased expression of TIMP1 mRNA20624997
D005576ColforsinColforsin results in increased expression of TIMP1 mRNA20378682
D003300Copper[ATP7B protein affects the susceptibility to Copper] which affects the expression of TIMP1 mRNA23112546
D003300Copper[glycyl-histidyl-lysine co-treated with Copper] results in increased secretion of TIMP1 protein11045606
D019327Copper SulfateCopper Sulfate results in increased expression of TIMP1 mRNA19549813
C102326cucurbitacin Ecucurbitacin E inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]27363783
C102326cucurbitacin Ecucurbitacin E results in decreased expression of TIMP1 mRNA27363783
C102326cucurbitacin Ecucurbitacin E results in decreased expression of TIMP1 protein27363783
D003471CuprizoneCuprizone results in increased expression of TIMP1 mRNA27523638
D003474CurcuminCurcumin results in decreased expression of TIMP1 protein17996675
D003474CurcuminCurcumin inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]27363783
D003474CurcuminCurcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]18200517
C004632cyanuric acid[cyanuric acid co-treated with melamine] results in increased expression of TIMP1 mRNA21784140
C004632cyanuric acid[melamine co-treated with cyanuric acid] results in increased expression of TIMP1 mRNA23022069
D003513CycloheximideTIMP1 protein results in decreased susceptibility to Cycloheximide15860571
C009160cyclonitecyclonite results in increased expression of TIMP1 mRNA25559034
D003520CyclophosphamideCyclophosphamide results in increased expression of TIMP1 mRNA23558518
D016572CyclosporineCyclosporine results in increased expression of TIMP1 mRNA10914799|2010694
D016572CyclosporineCyclosporine results in increased expression of TIMP1 mRNA21865292|2355851
C089595cylindrospermopsincylindrospermopsin results in increased expression of TIMP1 mRNA23726867
D003538CystamineCystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17708605
D003545CysteineCysteine inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]15158331
D003561CytarabineCytarabine results in decreased expression of TIMP1 mRNA21198554
C521634Dahuang Zhechong pillDahuang Zhechong pill results in decreased expression of TIMP1 mRNA18471418
C107676deguelindeguelin results in increased expression of TIMP1 protein25322282
D013759Dronabinol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
D013759DronabinolAM 251 inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
D013759DronabinolDronabinol results in increased expression of TIMP1 mRNA16330497|1815906
D013759DronabinolDronabinol results in increased expression of TIMP1 protein18159069|2219838
D013759DronabinolICAM1 mutant form inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]22198381
D013759Dronabinol[iodopravadoline co-treated with AM 251] inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
D013759Dronabinoliodopravadoline inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
D013759DronabinolN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dronabinol results in increased expression of TIMP1 mRNA]16330497
D013759DronabinolSB 203580 inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
D013759DronabinolTIMP1 results in increased susceptibility to Dronabinol18159069
D003703DemecolcineDemecolcine results in increased expression of TIMP1 mRNA23649840
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TIMP1 mRNA28628672
D003907Dexamethasone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA16054899
D003907DexamethasoneDexamethasone inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]28300665
D003907DexamethasoneDexamethasone results in decreased expression of TIMP1 mRNA22733784
D003907Dexamethasone[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA]16054899
D003907DexamethasoneTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA]16054899
D003907DexamethasoneDexamethasone results in increased expression of TIMP1 mRNA16718785
D003907DexamethasoneDexamethasone results in increased expression of TIMP1 protein16718785
C028009diallyl disulfidediallyl disulfide results in increased expression of TIMP1 mRNA20600798
C042577diallyl trisulfidediallyl trisulfide results in increased expression of TIMP1 mRNA24084732
C042577diallyl trisulfidediallyl trisulfide results in increased expression of TIMP1 protein24084732
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of TIMP1 mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of TIMP1 mRNA15829613|2126653
D002945Cisplatin[Cisplatin co-treated with Paclitaxel] results in increased expression of TIMP1 mRNA20705681
D002945CisplatinCisplatin results in increased expression of TIMP1 mRNA23287709
D002945CisplatinCisplatin results in increased expression of TIMP1 protein23287709
D002945CisplatinCisplatin results in increased expression of TIMP1 mRNA21151649
D002945CisplatinCisplatin results in increased expression of TIMP1 mRNA18289764
D002945CisplatinCisplatin results in increased expression of TIMP1 protein23287709
D004008DiclofenacDiclofenac results in increased expression of TIMP1 mRNA26934552
D004008DiclofenacDiclofenac results in decreased expression of TIMP1 mRNA19022234
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in increased expression of TIMP1 mRNA26924002
D019259LamivudineLamivudine results in decreased expression of TIMP1 protein15309715
D004041Dietary Fatsargatroban inhibits the reaction [Dietary Fats results in increased expression of TIMP1 mRNA]22841818
D004041Dietary Fats[Dietary Fats co-treated with Aurothioglucose] results in increased expression of TIMP1 protein21382165
D004041Dietary FatsDietary Fats promotes the reaction [arsenic acid results in increased expression of TIMP1 mRNA]18296743
D004041Dietary FatsDietary Fats promotes the reaction [arsenite results in increased expression of TIMP1 mRNA]18296743
D004041Dietary FatsDietary Fats results in decreased expression of TIMP1 mRNA25016146
D004041Dietary FatsDietary Fats results in increased expression of TIMP1 mRNA18042831|1829674
D004041Dietary Fats"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dietary Fats] results in decreased expression of TIMP1 mRNA"12097258
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of TIMP1 mRNA21527772
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of TIMP1 mRNA23288052
D004052Diethylnitrosaminecarfilzomib inhibits the reaction [Diethylnitrosamine results in increased expression of TIMP1 protein]24632418
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TIMP1 mRNA18164116|2004503
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA28943392
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of TIMP1 mRNA18665156
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of TIMP1 protein24632418
D004052DiethylnitrosamineIFNA1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TIMP1 mRNA]18665156
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of TIMP1 mRNA15890375
D004110DiltiazemDiltiazem inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein]27095094
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TIMP1 mRNA"22485181
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TIMP1 mRNA"12097258
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of TIMP1 mRNA17547211
D004128Dimethylnitrosaminebicyclol inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]16603200
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of TIMP1 mRNA16603200
D004128Dimethylnitrosamine2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]15723089
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of TIMP1 mRNA14600272|1506722
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of TIMP1 protein15504294|1627038
D004128Dimethylnitrosamine"Drugs, Chinese Herbal inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]"15339415|1703638
D004128Dimethylnitrosamine"Drugs, Chinese Herbal inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 protein]"16270385
D004128DimethylnitrosamineFlavonoids inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 protein]16270385
D004128Dimethylnitrosaminepirfenidone inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]15571005
D004128DimethylnitrosaminePlant Extracts inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]23485615
D004128DimethylnitrosaminePlant Preparations inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 protein]16270385
D004128Dimethylnitrosamineqishen yiqi inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]17432682
D004128Dimethylnitrosamine[silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]16169303
D004128DimethylnitrosamineValsartan inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]15504291
C024629dimethyl phthalatedimethyl phthalate results in increased expression of TIMP1 mRNA26924002
D004137DinitrochlorobenzeneDinitrochlorobenzene affects the expression of TIMP1 mRNA22302311
D004237DiuronDiuron metabolite results in increased expression of TIMP1 mRNA24172598
D004237DiuronDiuron results in decreased expression of TIMP1 mRNA25152437
D016291Dizocilpine MaleateDizocilpine Maleate inhibits the reaction [Homocysteine analog results in increased expression of TIMP1 mRNA]20406136
D016291Dizocilpine MaleateDizocilpine Maleate inhibits the reaction [Homocysteine analog results in increased expression of TIMP1 protein]20406136
D004298DopamineDopamine results in increased expression of TIMP1 mRNA21983523
D004317Doxorubicinbenazepril inhibits the reaction [Doxorubicin results in increased expression of TIMP1 mRNA]19357873
D004317Doxorubicinbenazepril inhibits the reaction [Doxorubicin results in increased expression of TIMP1 protein]19357873
D004317DoxorubicinDoxorubicin results in decreased expression of TIMP1 protein20051877
D004317DoxorubicinDoxorubicin results in increased expression of TIMP1 mRNA19357873|1991584
D004317DoxorubicinDoxorubicin results in increased expression of TIMP1 protein19357873
D004317Doxorubicin[Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]20051877
D004317DoxorubicinLisinopril inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]20051877
D004317DoxorubicinRazoxane inhibits the reaction [Doxorubicin results in increased expression of TIMP1 mRNA]19915844
D004317DoxorubicinTretinoin inhibits the reaction [Doxorubicin results in increased expression of TIMP1 mRNA]19357873
D004317DoxorubicinTretinoin inhibits the reaction [Doxorubicin results in increased expression of TIMP1 protein]19357873
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal affects the expression of TIMP1 mRNA"21812276
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]"15339415|1703638
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 protein]"16270385
C479799(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide results in increased expression of TIMP1 mRNA15528975
C042986ebselenebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]11903743
C045651epigallocatechin gallateepigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]20438794
D004918Erythromycin EstolateErythromycin Estolate results in increased expression of TIMP1 mRNA17522070
D000431Ethanolacanthoic acid inhibits the reaction [Ethanol results in increased expression of TIMP1 mRNA]28964808
D000431Ethanolacanthoic acid inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]28964808
D000431EthanolCNR1 gene mutant form inhibits the reaction [[Ethanol co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA]21863215
D000431Ethanol[Ethanol co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA21863215
D000431EthanolEthanol results in increased expression of TIMP1 mRNA28964808
D000431EthanolEthanol results in increased expression of TIMP1 protein28964808
D000431Ethanol[Thioacetamide co-treated with Ethanol] results in increased expression of TIMP1 protein16780996
D000431Ethanol"8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]"22063920
D000431Ethanolbetulinic acid inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]21172400
D000431Ethanolbetulin inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]21172400
D000431Ethanolcarvedilol inhibits the reaction [Ethanol results in increased expression of TIMP1 mRNA]22413959
D000431Ethanolcarvedilol inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]22413959
D000431EthanolEthanol results in increased expression of TIMP1 mRNA22413959|2327471
D000431EthanolEthanol results in increased expression of TIMP1 protein21172400|2206392
D000431EthanolGenistein inhibits the reaction [Ethanol results in increased expression of TIMP1 mRNA]23274713
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of TIMP1 mRNA16079270
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of TIMP1 mRNA17557909
C049347fasudilfasudil affects the expression of TIMP1 mRNA22465603
D011345FenofibrateFenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]19593819
D011345FenofibrateFenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]19593819
D011345FenofibrateFenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP1 mRNA]28871336
D011345FenofibrateNR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]19593819
D011345FenofibrateNR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]]19593819
D018818FenoldopamFenoldopam results in increased expression of TIMP1 mRNA21983523
C020326ferric nitrilotriacetateCYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA]16581302
C020326ferric nitrilotriacetate[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA16581302
C000499ferric oxide[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of TIMP1 mRNA20540983
C020748ferrous sulfateDiltiazem inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein]27095094
C020748ferrous sulfateferrous sulfate results in increased expression of TIMP1 protein27095094
C020748ferrous sulfateNimodipine inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein]27095094
C020748ferrous sulfateVerapamil inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein]27095094
C093230fexofenadinefexofenadine inhibits the reaction [TNF protein results in increased expression of TIMP1 protein]15663564
D005395Fish OilsFish Oils affects the reaction [NR1H4 protein affects the expression of TIMP1 mRNA]29142166
D005419FlavonoidsFlavonoids inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 protein]16270385
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of TIMP1 mRNA18678246
D005480FlurbiprofenFlurbiprofen results in increased expression of TIMP1 protein19501039
D005480Flurbiprofen[Flurbiprofen results in increased expression of TIMP1 protein] which results in decreased expression of MMP9 mRNA19501039
D005480Flurbiprofen[[Flurbiprofen results in increased expression of TIMP1 protein] which results in decreased expression of MMP9 mRNA] which results in decreased degradation of HPGD protein19501039
D005492Folic Acid[Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TIMP1 mRNA23439872
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TIMP1 mRNA20938992
D005492Folic AcidFolic Acid deficiency results in increased expression of TIMP1 mRNA20406136
D005557FormaldehydeFormaldehyde results in increased expression of TIMP1 mRNA23649840
D017328FosinoprilFosinopril results in decreased expression of TIMP1 mRNA21051829
D017328FosinoprilFosinopril results in decreased expression of TIMP1 protein21051829
D017328Fosinopril[Valsartan co-treated with Fosinopril] results in decreased expression of TIMP1 mRNA21051829
D017328Fosinopril[Valsartan co-treated with Fosinopril] results in decreased expression of TIMP1 protein21051829
C079574FR 139317FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TIMP1 mRNA]9175058
C104334FR 167653FR 167653 inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]17334410
C007789fucoidanfucoidan results in decreased secretion of TIMP1 protein16364234
C069837fullerene C60fullerene C60 results in increased expression of TIMP1 mRNA20064541
C039281furanfuran results in increased expression of TIMP1 mRNA15120968|2619464
C064925gadodiamide2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein]19561517
C064925gadodiamidegadodiamide results in increased expression of TIMP1 mRNA19561517
C064925gadodiamidegadodiamide results in increased expression of TIMP1 protein19561517
C064925gadodiamideU 0126 inhibits the reaction [gadodiamide results in increased expression of TIMP1 protein]19561517
C064925gadodiamidegadodiamide results in increased expression of TIMP1 protein20938346
D005707Gallic AcidGallic Acid inhibits the reaction [ALB modified form results in increased expression of TIMP1 mRNA]24309158
D019833GenisteinGenistein inhibits the reaction [Chromium results in increased expression of TIMP1 mRNA]15878362
D019833GenisteinGenistein inhibits the reaction [Cobalt results in increased expression of TIMP1 mRNA]15878362
D019833GenisteinGenistein inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA]15878362
D019833GenisteinGenistein results in decreased expression of TIMP1 mRNA15754008
D019833GenisteinGenistein inhibits the reaction [Ethanol results in increased expression of TIMP1 mRNA]23274713
D005839GentamicinsGentamicins affects the localization of TIMP1 protein20118187
D005839GentamicinsGentamicins results in decreased expression of TIMP1 mRNA18289764
D005839GentamicinsGentamicins results in increased secretion of TIMP1 protein20816719
D005897GlafenineGlafenine results in increased expression of TIMP1 mRNA24136188
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]17109745
D005944GlucosamineGlucosamine results in increased expression of TIMP1 mRNA17109745
D005944GlucosamineIL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA]17109745
D005947GlucoseGlucose deficiency results in increased secretion of TIMP1 protein24802182
C020905glycyl-histidyl-lysine[glycyl-histidyl-lysine co-treated with Copper] results in increased secretion of TIMP1 protein11045606
D056604Grape Seed ExtractGrape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]28300665
C568713GSK1210151AGSK1210151A inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]26644586
C568713GSK1210151AGSK1210151A results in decreased expression of TIMP1 mRNA26644586
C010176halofuginonehalofuginone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]16489207
C020754herbimycinherbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA]15878362
D006581HexachlorobenzeneHexachlorobenzene results in increased expression of TIMP1 mRNA15159207
C001335hexachlorobutadienehexachlorobutadiene results in decreased expression of TIMP1 mRNA21905055
C001335hexachlorobutadienehexachlorobutadiene results in increased expression of TIMP1 mRNA21905055
C001335hexachlorobutadienehexachlorobutadiene results in increased expression of TIMP1 protein21259293
D017313FenretinideFenretinide results in increased expression of TIMP1 mRNA28973697
D006861Hydrogen PeroxideAscorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TIMP1 protein]20881940
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of TIMP1 protein20881940|2302251
D006861Hydrogen Peroxidetetramethylpyrazine inhibits the reaction [Hydrogen Peroxide results in increased expression of TIMP1 protein]23022513
C119203ilomastatilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]18837084
C119203ilomastatilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein]18837084
C056493imiquimodimiquimod results in increased expression of TIMP1 protein14708627
C082770IMM 125IMM 125 results in increased expression of TIMP1 mRNA20118187
D007166Immunosuppressive AgentsImmunosuppressive Agents results in decreased expression of TIMP1 protein19652986
C041508indeno(1,2,3-cd)pyrene"indeno(1,2,3-cd)pyrene results in increased expression of TIMP1 mRNA"22579512
C041508indeno(1,2,3-cd)pyrene"indeno(1,2,3-cd)pyrene results in decreased expression of TIMP1 mRNA"26377693
D007213IndomethacinIndomethacin results in increased expression of TIMP1 protein11719597
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TIMP1 mRNA28628672
D007213IndomethacinIndomethacin results in increased expression of TIMP1 protein17000239
D053590Interleukin 1 Receptor Antagonist ProteinInterleukin 1 Receptor Antagonist Protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]16762003
D053590Interleukin 1 Receptor Antagonist ProteinInterleukin 1 Receptor Antagonist Protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]16762003
C094023iodopravadoline[iodopravadoline co-treated with AM 251] inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
C094023iodopravadoline[iodopravadoline co-treated with AM 251] inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C094023iodopravadolineiodopravadoline inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
C094023iodopravadolineiodopravadoline inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TIMP1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA16054899
D0150561-Methyl-3-isobutylxanthine[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA]16054899
D0150561-Methyl-3-isobutylxanthineTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA]16054899
D007545IsoproterenolIsoproterenol results in decreased expression of TIMP1 mRNA24286936
D007545IsoproterenolIsoproterenol results in increased expression of TIMP1 mRNA20003209
D007545IsoproterenolIsoproterenol results in increased expression of TIMP1 mRNA20211217|2355851
D007545IsoproterenolIsoproterenol results in increased expression of TIMP1 protein24286936
C016527isoquercitrinisoquercitrin results in increased expression of TIMP1 protein18715546
C432511isorhamnetin 3-O-glucosideisorhamnetin 3-O-glucoside results in increased expression of TIMP1 protein18715546
C098607JP8 aviation fuelJP8 aviation fuel affects the expression of TIMP1 mRNA17085751
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of TIMP1 protein17337753
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]26644586
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of TIMP1 mRNA25961927|2664458
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]26644586
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of TIMP1 mRNA26644586
C410337K 7174K 7174 results in increased expression of TIMP1 mRNA24086573
D007654KetoconazoleKetoconazole results in decreased expression of TIMP1 mRNA18289764
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 affects the expression of TIMP1 mRNA"18986645
C433788lipopolysaccharide, E. coli O26-B6"[Nicotine co-treated with lipopolysaccharide, E. coli O26-B6] affects the expression of TIMP1 mRNA"18986645
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of TIMP1 mRNA"11578593
C440499lipopolysaccharide, Escherichia coli O111 B4"Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TIMP1 mRNA]"15734790
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TIMP1 mRNA"15734790
C440499lipopolysaccharide, Escherichia coli O111 B4"resveratrol affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TIMP1 mRNA]"15734790
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TIMP1 mRNA22169119|2358587
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TIMP1 protein19133137
D008070Lipopolysaccharidesterameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of TIMP1 protein]19133137
C068538liposomal amphotericin Bliposomal amphotericin B results in increased expression of TIMP1 mRNA22863853
D017706Lisinopril[Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]20051877
D017706LisinoprilLisinopril inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]20051877
D008095Lithocholic AcidLithocholic Acid results in increased expression of TIMP1 mRNA16436656
C059451lornoxicamlornoxicam results in increased expression of TIMP1 mRNA23142791
D019808LosartanLosartan inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]25233898
D019808LosartanLosartan inhibits the reaction [Simvastatin results in decreased expression of TIMP1 mRNA]20137537
D019808LosartanLosartan results in decreased expression of TIMP1 mRNA20137537
D019808LosartanSimvastatin inhibits the reaction [Losartan results in decreased expression of TIMP1 mRNA]20137537
C032881lysophosphatidic acid3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of TIMP1 protein]25822713
C032881lysophosphatidic acidlysophosphatidic acid results in increased expression of TIMP1 protein25822713
D058185Magnetite Nanoparticles[Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of TIMP1 mRNA20540983
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of TIMP1 protein]17395008
D008468MeclizineMeclizine affects the expression of TIMP1 protein12388792
D008535MegestrolMegestrol affects the expression of TIMP1 protein12388792
C011907melamine[cyanuric acid co-treated with melamine] results in increased expression of TIMP1 mRNA21784140
C011907melamine[melamine co-treated with cyanuric acid] results in increased expression of TIMP1 mRNA23022069
D008610Menthol[Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of and results in increased secretion of TIMP1 protein27818348
D008627Mercuric ChlorideMercuric Chloride results in increased expression of TIMP1 mRNA11817102
D008628MercuryMercury binds to and results in increased degradation of TIMP1 protein12916640
D009921MetaproterenolMetaproterenol results in increased expression of TIMP1 mRNA23558518
D008694MethamphetamineMethamphetamine results in increased expression of TIMP1 mRNA19564919
C088155methanandamide2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C088155methanandamideAM 251 inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C088155methanandamidecapsazepine inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C088155methanandamideICAM1 mutant form inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]22198381
C088155methanandamide[iodopravadoline co-treated with AM 251] inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C088155methanandamideiodopravadoline inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C088155methanandamidemethanandamide results in increased expression of TIMP1 mRNA16330497|1815906
C088155methanandamidemethanandamide results in increased expression of TIMP1 protein16330497|1815906
C088155methanandamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [methanandamide results in increased expression of TIMP1 mRNA]16330497
C088155methanandamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]16330497
C088155methanandamideSB 203580 inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C088155methanandamideTIMP1 results in increased susceptibility to methanandamide18159069
D008701MethapyrileneMethapyrilene results in increased expression of TIMP1 mRNA15890375
D008704MethazolamideMethazolamide affects the expression of TIMP1 protein12388792
D008715Methionine"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA"28973532
D008715Methionine"3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]"28163111
D008715MethionineBezafibrate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA]18513333
D008715Methionine[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA18513333
D008715MethionineFenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]19593819
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with aroclor 1260] results in increased expression of TIMP1 mRNA28163111
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TIMP1 mRNA20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA19593819|2069737
D008715MethionineNR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]]19593819
D008715Methioninepirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]19593819
D008715MethionineQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]22915297
D008715MethionineMethionine inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]15158331
C017501methylamphotericin Bmethylamphotericin B results in increased expression of TIMP1 mRNA22863853
D008748MethylcholanthreneMethylcholanthrene results in increased expression of TIMP1 mRNA22579512
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of TIMP1 mRNA28001369
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of TIMP1 protein28526320
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of TIMP1 mRNA21628967
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of TIMP1 mRNA17412507
C000873methylprednisolone acetatemethylprednisolone acetate results in decreased expression of TIMP1 mRNA15693093
C051602mifobatemifobate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein]28416457
D008942MitoxantroneMitoxantrone results in increased expression of TIMP1 mRNA23558518
C016599mono-(2-ethylhexyl)phthalate2-chloro-5-nitrobenzanilide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein]28416457
C016599mono-(2-ethylhexyl)phthalatemifobate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein]28416457
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein28416457
C016599mono-(2-ethylhexyl)phthalatePPARG mRNA promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein]28416457
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in decreased expression of TIMP1 mRNA22401849
D016686MonocrotalineMonocrotaline results in increased expression of TIMP1 mRNA22022327
D016686MonocrotalineSimvastatin inhibits the reaction [Monocrotaline results in increased expression of TIMP1 mRNA]22022327
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased expression of TIMP1 protein24625837
C517284monomethyl phthalatemonomethyl phthalate affects the expression of TIMP1 mRNA26924002
C500085muraglitazarmuraglitazar results in decreased expression of TIMP1 mRNA21515302
D009151Mustard GasMustard Gas results in increased expression of TIMP1 mRNA18988085
C451426N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide"N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of TIMP1 mRNA"25461557
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of TIMP1 mRNA]16330497
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dronabinol results in increased expression of TIMP1 mRNA]16330497
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [methanandamide results in increased expression of TIMP1 mRNA]16330497
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]16330497
C028473N-acetyl-4-benzoquinoneimineN-acetyl-4-benzoquinoneimine results in increased expression of TIMP1 mRNA28286204
D009270NaloxoneNaloxone results in increased expression of TIMP1 mRNA17522070
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of TIMP1 mRNA"23845593
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of TIMP1 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of TIMP1 mRNA"24664304|2555468
C031721naphthalenenaphthalene results in increased expression of TIMP1 mRNA22579512
C031721naphthalenenaphthalene results in increased expression of TIMP1 mRNA18978301
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA21037076|2463342
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of TIMP1 protein22094456
D0150581-NaphthylisothiocyanateF2R protein promotes the reaction [1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA]21037076
D0150581-NaphthylisothiocyanateF3 protein promotes the reaction [1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA]21037076
D0150581-NaphthylisothiocyanateTranexamic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA]24633426
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA17522070|2355851
D009288Naproxen[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]22150557
D009288NaproxenNaproxen inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]22150557
C005274naringinnaringin inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]23603004
C005274naringinnaringin inhibits the reaction [Paraquat results in increased expression of TIMP1 protein]23603004
D010866NatamycinNatamycin results in increased expression of TIMP1 mRNA22863853
C017096n-butoxyethanoln-butoxyethanol results in increased expression of TIMP1 mRNA19812364
D009532NickelNickel results in increased expression of TIMP121401309
D009532NickelNickel results in increased expression of TIMP1 mRNA24768652|2558310
C029938nickel sulfatenickel sulfate results in increased expression of TIMP1 mRNA16780908
C029938nickel sulfatenickel sulfate results in increased expression of TIMP1 mRNA16100012
C029938nickel sulfatenickel sulfate results in increased expression of TIMP1 mRNA11114790
D009538NicotineNicotine affects the expression of TIMP1 mRNA18986645
D009538Nicotine"[Nicotine co-treated with lipopolysaccharide, E. coli O26-B6] affects the expression of TIMP1 mRNA"18986645
D009553NimodipineNimodipine inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein]27095094
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of TIMP1 mRNA17616710
C002741N-nitrosomorpholineN-nitrosomorpholine results in increased expression of TIMP1 mRNA19716841
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of TIMP1 mRNA27935865
D009711NucleotidesNucleotides inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]11925456
D009761NystatinNystatin results in increased expression of TIMP1 mRNA22863853
C464660obeticholic acidobeticholic acid results in decreased expression of TIMP1 mRNA27939613
C464660obeticholic acidNR0B2 protein affects the reaction [obeticholic acid inhibits the reaction [JUND protein binds to TIMP1 promoter]]15860571
C464660obeticholic acidNR0B2 protein affects the reaction [obeticholic acid results in decreased expression of and results in decreased secretion of TIMP1 protein]15860571
C464660obeticholic acidobeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]15860571
C464660obeticholic acidobeticholic acid results in decreased expression of and results in decreased secretion of TIMP1 protein15860571
C025589ochratoxin Aochratoxin A results in increased expression of TIMP1 mRNA16622519|1830870
C025589ochratoxin Aochratoxin A results in increased expression of TIMP1 protein18308701
D019301Oleic Acid[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TIMP1 mRNA26187275
D015242OfloxacinOfloxacin results in decreased expression of TIMP1 mRNA21903125
D009828Oleanolic AcidOleanolic Acid analog inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17922224
D000069463Olive OilOlive Oil promotes the reaction [Streptozocin results in increased activity of TIMP1 protein]25246140
D000069463Olive OilOlive Oil results in increased activity of TIMP1 protein25246140
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of TIMP1 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of TIMP1 mRNA25729387
D010100Oxygen"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein]]"27274199
D010100Oxygen[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein27274199
D010100OxygenOxygen deficiency results in increased expression of TIMP1 mRNA16980344
D010100OxygenOxygen results in increased expression of TIMP1 mRNA22911455
D010100Oxygen[Paraquat co-treated with Oxygen] results in increased expression of TIMP1 mRNA12882763
D010100Oxygenursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein]27274199
C037573oxymatrineoxymatrine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]15633229
D010126Ozone[Ozone co-treated with NOTCH3 gene mutant form] results in increased expression of TIMP1 mRNA25658374
D010126OzoneOzone results in increased expression of TIMP1 mRNA12763052|1955522
D010126OzoneTTPA protein affects the reaction [Ozone results in increased expression of TIMP1 mRNA]19555225
D010126Ozone[Ozone co-treated with Chlorine] results in decreased expression of TIMP1 mRNA18636392
D017239Paclitaxel[Cisplatin co-treated with Paclitaxel] results in increased expression of TIMP1 mRNA20705681
D019308Palmitic Acid[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TIMP1 mRNA26187275
D000073878Palm OilPalm Oil results in increased expression of TIMP1 mRNA18042831
D010269Paraquat[CTGF protein co-treated with Paraquat] affects the expression of TIMP1 mRNA26129822
D010269ParaquatADIPOQ protein inhibits the reaction [Paraquat results in increased expression of TIMP1 protein]25945502
D010269Paraquatnaringin inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]23603004
D010269Paraquatnaringin inhibits the reaction [Paraquat results in increased expression of TIMP1 protein]23603004
D010269ParaquatParaquat results in decreased expression of TIMP1 protein26988026
D010269ParaquatParaquat results in increased expression of TIMP1 mRNA17215068|2360300
D010269ParaquatParaquat results in increased expression of TIMP1 protein23603004|2594550
D010269ParaquatLosartan inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]25233898
D010269Paraquat[Paraquat co-treated with Oxygen] results in increased expression of TIMP1 mRNA12882763
D010269ParaquatParaquat results in decreased expression of TIMP1 mRNA18198484
D010269ParaquatParaquat results in increased expression of TIMP1 mRNA19272247|2104069
D010269Paraquatphenylmethylpyrazolone inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]21040696
D010269Paraquatpyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]19272247
D052638Particulate MatterParticulate Matter results in increased expression of TIMP1 mRNA21708214
D010431PentoxifyllinePentoxifylline results in increased expression of TIMP1 mRNA11788567
C027579periodate-oxidized adenosineperiodate-oxidized adenosine affects the expression of TIMP1 mRNA17097637
D015232DinoprostoneDinoprostone results in increased expression of TIMP1 mRNA16330497
D015232DinoprostoneDinoprostone results in increased expression of TIMP1 protein16330497
D015232DinoprostoneDinoprostone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]]25432964
C031181phenanthrenephenanthrene results in increased expression of TIMP1 mRNA22579512
D010634PhenobarbitalPhenobarbital results in increased expression of TIMP1 mRNA19162173
D010656PhenylephrineBCL2 protein affects the reaction [Phenylephrine results in increased expression of TIMP1 protein]19910689
D010656PhenylephrinePhenylephrine results in increased expression of TIMP1 mRNA18158353|1991068
D010656PhenylephrinePhenylephrine results in increased expression of TIMP1 protein19910689
D010656PhenylephrinePTHLH protein affects the reaction [Phenylephrine results in increased expression of TIMP1 mRNA]19910689
D010656PhenylephrinePTHLH protein affects the reaction [Phenylephrine results in increased expression of TIMP1 protein]19910689
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]21040696
D010672PhenytoinPhenytoin results in increased expression of TIMP1 mRNA10914799|1474168
D010672PhenytoinPhenytoin results in increased expression of TIMP1 protein15948689
D010705PhosgenePhosgene affects the expression of TIMP1 mRNA16300373
D010713Phosphatidylcholines[silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]16169303
D010767PhosphorylcholineGenistein inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA]15878362
D010767Phosphorylcholineherbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA]15878362
D010767PhosphorylcholinePhosphorylcholine analog results in increased expression of TIMP1 mRNA15878362
D009764o-Phthalaldehydeo-Phthalaldehyde affects the expression of TIMP1 mRNA22302311
C004479pimagedinepimagedine results in increased expression of TIMP1 mRNA18380797
C060836pioglitazonepioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]16484506
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of TIMP1 mRNA15890375
C093844pirfenidonepirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]12445421
C093844pirfenidonepirfenidone inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]15571005
C093844pirfenidonepirfenidone promotes the reaction [Tacrolimus results in decreased expression of TIMP1 mRNA]15854665
C006253pirinixic acidpirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]19593819
C006253pirinixic acidpirinixic acid results in increased expression of TIMP1 mRNA20813756
C006253pirinixic acidpirinixic acid results in increased expression of TIMP1 mRNA15890375
D010936Plant ExtractsPlant Extracts results in increased expression of TIMP1 mRNA23232078
D010936Plant ExtractsPlant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17157831
D010936Plant ExtractsPlant Extracts inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]23485615
D028321Plant PreparationsPlant Preparations inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 protein]16270385
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in increased expression of TIMP1 mRNA25716161
D011070Poly I-CPoly I-C results in increased expression of TIMP1 mRNA21195166
D017035PravastatinPravastatin results in decreased expression of TIMP1 mRNA16935385
D011374Progesterone[Progesterone co-treated with Estradiol] results in increased expression of TIMP1 mRNA20226447
D011374ProgesteroneProgesterone results in increased expression of TIMP1 mRNA20226447
D000527AlprostadilAlprostadil results in decreased expression of TIMP116859129
D015237DinoprostDinoprost results in decreased expression of TIMP1 protein11719597
C010313pseudocumenepseudocumene results in increased expression of TIMP1 protein17337753
C033607puerarinpuerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]23500774
C526689punarnavinepunarnavine results in increased expression of TIMP1 mRNA18075866
C526689punarnavinepunarnavine results in increased expression of TIMP1 protein18075866
D011692Puromycin AminonucleosideFR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TIMP1 mRNA]9175058
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased expression of TIMP1 mRNA9175058
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [thymoquinone results in increased expression of TIMP1 protein]27060453
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]19272247
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TIMP1 mRNA]12472797
C528580qishen yiqiqishen yiqi inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]17432682
D011791Quartz[Ascorbic Acid co-treated with Quartz] results in increased expression of TIMP1 mRNA27381660
D011794Quercetin"Quercetin promotes the reaction [Cholesterol, LDL results in increased expression of TIMP1 mRNA]"11414687
D011794QuercetinQuercetin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA]11414687
D011794QuercetinQuercetin results in decreased expression of TIMP1 mRNA11506819
D011794QuercetinQuercetin results in decreased expression of TIMP1 protein11506819
D011794QuercetinQuercetin results in increased expression of TIMP1 mRNA11414687|2163298
D011794QuercetinQuercetin results in increased expression of TIMP1 protein11414687
D011794QuercetinQuercetin inhibits the reaction [Calcium Chloride results in decreased expression of TIMP1 mRNA]22728078
D011794QuercetinQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]22915297
D011794Quercetin[Quercetin co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA22989100
D011802QuinidineQuinidine results in increased expression of TIMP1 mRNA17522070
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of TIMP1 mRNA16202921
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride affects the expression of TIMP1 mRNA16079270
D011929RazoxaneRazoxane inhibits the reaction [Doxorubicin results in increased expression of TIMP1 mRNA]19915844
C059514resveratrolresveratrol results in decreased expression of TIMP1 protein25128170
C059514resveratrolresveratrol results in decreased expression of TIMP1 mRNA22086758|2539464
C059514resveratrol"resveratrol affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TIMP1 mRNA]"15734790
C059514resveratrol[resveratrol co-treated with Streptozocin] results in increased expression of TIMP1 mRNA25905778
C059514resveratrolresveratrol results in increased expression of TIMP1 mRNA25905778
D015474IsotretinoinIsotretinoin results in increased expression of TIMP1 protein19066126
C089032rimonabantrimonabant results in decreased expression of TIMP1 mRNA21863215
C089730rosiglitazone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA16054899
C089730rosiglitazone[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA]16054899
C089730rosiglitazoneTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA]16054899
C089730rosiglitazonerosiglitazone results in decreased expression of TIMP1 mRNA21515302
C541923sandostatinLARsandostatinLAR results in increased expression of TIMP1 mRNA17210224
C093642SB 203580SB 203580 inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]18159069
C093642SB 203580SB 203580 inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]18159069
C093642SB 203580SB 203580 inhibits the reaction [thymoquinone results in increased expression of TIMP1 protein]27060453
C115461SC 560SC 560 inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]25432964
D012643SeleniumSelenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP1 protein]21144892
D012643SeleniumSelenium results in decreased expression of TIMP1 mRNA17390030
D012643SeleniumSelenium deficiency results in increased expression of TIMP1 mRNA11444866
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of TIMP1 mRNA"16571779|2151441
D017632Asbestos, Serpentine"SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of TIMP1 mRNA]"21514415
D017632Asbestos, Serpentine"U 0126 inhibits the reaction [Asbestos, Serpentine results in increased expression of TIMP1 mRNA]"16571779
D012822Silicon DioxideSilicon Dioxide analog affects the secretion of TIMP1 protein25895662
D012822Silicon DioxideSilicon Dioxide results in increased expression of TIMP1 mRNA23221170|2634525
D012822Silicon DioxideSilicon Dioxide results in increased expression of TIMP1 protein27428020
C440975silybin[silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]16169303
D019821SimvastatinSimvastatin results in decreased expression of TIMP119801495
D019821SimvastatinLosartan inhibits the reaction [Simvastatin results in decreased expression of TIMP1 mRNA]20137537
D019821SimvastatinSimvastatin inhibits the reaction [Losartan results in decreased expression of TIMP1 mRNA]20137537
D019821SimvastatinSimvastatin inhibits the reaction [Monocrotaline results in increased expression of TIMP1 mRNA]22022327
D019821SimvastatinSimvastatin results in decreased expression of TIMP1 mRNA16414398|2013753
D012906SmokeSmoke results in increased expression of TIMP1 mRNA21095227
D012906SmokeSmoke results in increased expression of TIMP1 mRNA20937366
C017947sodium arsenitesodium arsenite results in increased expression of TIMP1 mRNA21134390
C016104sodium bichromatesodium bichromate results in increased expression of TIMP1 mRNA25993096
C012037solasodinesolasodine results in increased expression of TIMP1 mRNA28283413
D053260SootSoot results in increased expression of TIMP1 mRNA22461453|2655175
D013148SpironolactoneSpironolactone results in increased expression of TIMP1 protein20082611
D013311StreptozocinOlive Oil promotes the reaction [Streptozocin results in increased activity of TIMP1 protein]25246140
D013311Streptozocin[resveratrol co-treated with Streptozocin] results in increased expression of TIMP1 mRNA25905778
D013311StreptozocinStreptozocin results in increased activity of TIMP1 protein25246140
D013311StreptozocinStreptozocin results in increased expression of TIMP1 mRNA18246672
D012460SulfasalazineSulfasalazine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]15633128
C016766sulforafansulforafan results in increased expression of TIMP1 mRNA26833863
D013467SulindacSulindac affects the expression of TIMP1 protein12388792
D018170Sumatriptan[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]22150557
D018170SumatriptanSumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]22150557
C473478sunitinibCarnitine inhibits the reaction [sunitinib results in increased expression of TIMP1 mRNA]26581635
C473478sunitinibsunitinib results in increased expression of TIMP1 mRNA26581635
D013605T-2 ToxinSelenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP1 protein]21144892
D013605T-2 ToxinT-2 Toxin results in decreased expression of TIMP1 protein21144892
D013605T-2 ToxinT-2 Toxin affects the expression of TIMP1 mRNA21112371
D016559Tacrolimuspirfenidone promotes the reaction [Tacrolimus results in decreased expression of TIMP1 mRNA]15854665
D016559Tacrolimuspyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TIMP1 mRNA]12472797
D016559TacrolimusTacrolimus results in decreased expression of TIMP1 mRNA11091246|1585466
D016559TacrolimusTacrolimus results in increased expression of TIMP1 mRNA12472797|2186529
C061133tamibarotenetamibarotene results in increased expression of TIMP1 mRNA15498508
C087114tebuconazoletebuconazole results in increased expression of TIMP1 mRNA26852204
C076852terameprocolterameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of TIMP1 protein]19133137
C501413tesaglitazartesaglitazar results in decreased expression of TIMP1 mRNA21515302
C045037testosterone-3-carboxymethyloxime-bovine serum albumin conjugatetestosterone-3-carboxymethyloxime-bovine serum albumin conjugate results in increased expression of TIMP1 mRNA20189893
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased expression of TIMP1 mRNA25172293
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of TIMP1 mRNA28300664
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of TIMP1 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA27693115
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA]16054899
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with EGF protein] results in increased expression of TIMP1 mRNA16054899
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA]16054899
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of TIMP1 mRNA16054899|1758670
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TIMP1 mRNA19770486
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TIMP1 mRNA15644576|2095900
D013752TetracyclineTetracycline results in increased expression of TIMP1 mRNA17522070
C117155tetracycline CMT-3tetracycline CMT-3 results in decreased secretion of TIMP1 protein11857423
C117155tetracycline CMT-3tetracycline CMT-3 results in decreased secretion of TIMP1 protein11857423
C117155tetracycline CMT-3tetracycline CMT-3 results in increased expression of TIMP1 protein16003065
D013755Tetradecanoylphorbol AcetateQuercetin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA]11414687
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA11414687|1815551
D013755Tetradecanoylphorbol Acetatetroglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA]18155510
C017953tetramethylpyrazinetetramethylpyrazine inhibits the reaction [Hydrogen Peroxide results in increased expression of TIMP1 protein]23022513
D013792ThalidomideThalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]17030452
D013792ThalidomideThalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]17030452
D013792ThalidomideThalidomide inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]15464241
D013806TheophyllineTheophylline results in increased expression of TIMP1 mRNA17522070
D013853ThioacetamideCNR1 gene mutant form inhibits the reaction [[Ethanol co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA]21863215
D013853Thioacetamidecucurbitacin E inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]27363783
D013853ThioacetamideCurcumin inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]27363783
D013853Thioacetamide[Ethanol co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA21863215
D013853ThioacetamideIL10 protein inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]16126171
D013853ThioacetamideKRT18 protein affects the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]18395095
D013853ThioacetamidePOMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of and results in increased activity of TIMP1 protein]16511523
D013853ThioacetamidePOMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]16511523
D013853Thioacetamide[Thioacetamide co-treated with Ethanol] results in increased expression of TIMP1 protein16780996
D013853ThioacetamideThioacetamide results in increased expression of and results in increased activity of TIMP1 protein16511523
D013853ThioacetamideThioacetamide results in increased expression of TIMP1 mRNA16126171|1651152
D013853ThioacetamideThioacetamide results in increased expression of TIMP1 protein27363783
D013853ThioacetamideCysteine inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]15158331
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA28943392
D013853Thioacetamidehalofuginone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]16489207
D013853ThioacetamideMethionine inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]15158331
D013853ThioacetamideNucleotides inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]11925456
D013853ThioacetamideThalidomide inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]15464241
D013853ThioacetamideThioacetamide results in increased expression of TIMP1 mRNA15158331|1546424
D013853ThioacetamideThioacetamide results in increased expression of TIMP1 protein11925456
C003466thymoquinonepyrazolanthrone inhibits the reaction [thymoquinone results in increased expression of TIMP1 protein]27060453
C003466thymoquinoneSB 203580 inhibits the reaction [thymoquinone results in increased expression of TIMP1 protein]27060453
C003466thymoquinonethymoquinone inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 protein]27688165
C003466thymoquinonethymoquinone results in increased expression of TIMP1 protein27060453
D014025TitaniumTitanium results in increased secretion of TIMP1 protein14661256
C009495titanium dioxidetitanium dioxide results in increased expression of TIMP1 mRNA21259345|2355797
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TIMP1 mRNA22363418
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of TIMP1 mRNA27404394|2786577
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of TIMP1 protein27865774
D014028Tobacco Smoke Pollution[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of TIMP1 mRNA24096154
D014028Tobacco Smoke Pollution[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of TIMP1 protein24096154
D014028Tobacco Smoke PollutionNFE2L2 protein affects the reaction [Tobacco Smoke Pollution affects the expression of TIMP1 mRNA]20133372
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of TIMP1 mRNA20133372
D014028Tobacco Smoke PollutionTobacco Smoke Pollution deficiency inhibits the reaction [[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of TIMP1 protein]24096154
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TIMP1 mRNA28111298
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of and results in increased secretion of TIMP1 protein26609137
D014028Tobacco Smoke Pollution[Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of and results in increased secretion of TIMP1 protein27818348
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of and results in increased activity of TIMP1 protein"12534559
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of TIMP1 mRNA"14987308
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased expression of TIMP1 protein"14987308
C003677tomatidinetomatidine results in increased expression of TIMP1 mRNA23566884
C513941tongxinluotongxinluo results in decreased expression of TIMP119801495
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of TIMP1 mRNA25729387
D019772TopotecanTopotecan results in increased expression of TIMP1 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of TIMP1 mRNA"19682533
D014148Tranexamic AcidTranexamic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA]24633426
D014212Tretinoin[Tretinoin co-treated with OSM protein] results in increased expression of TIMP1 mRNA16467367
D014212TretinoinTretinoin results in increased expression of TIMP1 mRNA15498508|1646736
D014212TretinoinTretinoin inhibits the reaction [Doxorubicin results in increased expression of TIMP1 mRNA]19357873
D014212TretinoinTretinoin inhibits the reaction [Doxorubicin results in increased expression of TIMP1 protein]19357873
D014260TriclosanTriclosan results in decreased expression of TIMP1 mRNA26604029
C015559trimellitic anhydridetrimellitic anhydride affects the expression of TIMP1 mRNA22302311
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of TIMP1 mRNA19042947
D014302Trinitrobenzenesulfonic AcidCurcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]18200517
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA17982090|1820051
D014302Trinitrobenzenesulfonic Acidilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]18837084
D014302Trinitrobenzenesulfonic Acidilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein]18837084
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA18837084
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein18837084
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of TIMP1 mRNA"26179874
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of TIMP1 mRNA29024780
C057693troglitazonetroglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA]18155510
C113580U 0126U 0126 inhibits the reaction [CD82 protein affects the expression of TIMP1]20075392
C113580U 0126U 0126 inhibits the reaction [gadodiamide results in increased expression of TIMP1 protein]19561517
C113580U 0126"U 0126 inhibits the reaction [Asbestos, Serpentine results in increased expression of TIMP1 mRNA]"16571779
C022884undecaneundecane results in increased expression of TIMP1 protein17337753
D014520UrethaneUrethane results in increased expression of TIMP1 mRNA28818685
C005466ursolic acid"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein]]"27274199
C005466ursolic acidursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein]27274199
D014635Valproic AcidValproic Acid affects the expression of TIMP1 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased methylation of TIMP1 gene29154799
D000068756ValsartanValsartan inhibits the reaction [AGT protein results in increased expression of TIMP1 mRNA]12846741
D000068756ValsartanValsartan inhibits the reaction [AGT protein results in increased expression of TIMP1 protein]12846741
D000068756Valsartan[Valsartan co-treated with Fosinopril] results in decreased expression of TIMP1 mRNA21051829
D000068756Valsartan[Valsartan co-treated with Fosinopril] results in decreased expression of TIMP1 protein21051829
D000068756ValsartanValsartan inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]15504291
D000068756ValsartanValsartan results in decreased expression of TIMP1 mRNA21051829
D000068756ValsartanValsartan results in decreased expression of TIMP1 protein21051829
D014639VanadiumVanadium results in decreased expression of TIMP1 mRNA19000753
D017968Vanadium CompoundsVanadium Compounds results in increased expression of TIMP1 mRNA11114790
D014640VancomycinVancomycin results in increased expression of TIMP1 mRNA18289764
D014700VerapamilVerapamil affects the expression of TIMP1 protein12388792
D014700VerapamilVerapamil inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein]27095094
C573672VI-14 flavonoidVI-14 flavonoid results in increased expression of TIMP1 protein22538171
D014747VinblastineVinblastine results in increased expression of TIMP1 mRNA20624997
C025643vinclozolinvinclozolin affects the expression of TIMP1 mRNA19015723
C025643vinclozolinvinclozolin results in increased expression of TIMP1 mRNA22570695
D014750VincristineVincristine results in increased expression of TIMP1 mRNA23649840
D014750VincristineVincristine results in increased expression of TIMP1 mRNA20624997
C029297vinylidene chloridevinylidene chloride results in increased expression of TIMP1 mRNA26682919
D014810Vitamin EVitamin E results in increased expression of TIMP1 mRNA19244175
D014810Vitamin E[silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]16169303
C581157XL147[N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of TIMP1 mRNA27935865
C066632yessotoxinyessotoxin results in increased expression of TIMP1 protein27104637
C017803zinc protoporphyrinzinc protoporphyrin promotes the reaction [ALB protein results in increased expression of TIMP1 protein]21163135
C017803zinc protoporphyrinzinc protoporphyrin affects the expression of TIMP123704825
C028541zirconium oxidezirconium oxide results in increased secretion of TIMP1 protein14661256
C088658zoledronic acidzoledronic acid results in increased expression of TIMP1 mRNA28871336
C088658zoledronic acidzoledronic acid results in increased expression of TIMP1 protein28871336
C088658zoledronic acidFenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP1 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of TIMP1 mRNA]28871336
C088658zoledronic acidzoledronic acid results in increased expression of TIMP1 mRNA28871336
D015054ZymosanNCF1 protein affects the reaction [Zymosan results in increased expression of TIMP1 mRNA]14507659
D015054ZymosanZymosan results in increased expression of TIMP1 mRNA14507659

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0002020protease binding-IBA21873635  
GO:0005125cytokine activity-IDA3839290  
GO:0005515protein binding-IPI2251898  16917503  20979576  24330623  
GO:0008083growth factor activity-IEA-  
GO:0008191metalloendopeptidase inhibitor activity-IBA21873635  
GO:0008191metalloendopeptidase inhibitor activity-IDA3903517  12714508  
GO:0008270zinc ion binding-IDA22427646  
GO:0030414peptidase inhibitor activity-IDA9573338  
GO ID GO Term Qualifier Evidence PubMed
GO:0001775cell activation-IEA-  
GO:0002248connective tissue replacement involved in inflammatory response wound healing-IEA-  
GO:0002576platelet degranulation-TAS-  
GO:0007568aging-IEA-  
GO:0008284positive regulation of cell proliferation-IDA3839290  
GO:0009725response to hormone-IBA21873635  
GO:0010033response to organic substance-IBA21873635  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0010951negative regulation of endopeptidase activity-IBA21873635  
GO:0010951negative regulation of endopeptidase activity-IDA3903517  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0022617extracellular matrix disassembly-TAS-  
GO:0034097response to cytokine-IBA21873635  
GO:0043066negative regulation of apoptotic process-IEA-  
GO:0043086negative regulation of catalytic activity-IDA3903517  
GO:0043434response to peptide hormone-IEA-  
GO:0043687post-translational protein modification-TAS-  
GO:0044267cellular protein metabolic process-TAS-  
GO:0051045negative regulation of membrane protein ectodomain proteolysis-IBA21873635  
GO:0051045negative regulation of membrane protein ectodomain proteolysis-IDA12714508  
GO:0051216cartilage development-IEA-  
GO:1901164negative regulation of trophoblast cell migration-IMP21356369  
GO:1905049negative regulation of metallopeptidase activity-IDA9573338  
GO:2001044regulation of integrin-mediated signaling pathway-IMP16917503  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-NAS1653055  
GO:0005576extracellular region-TAS-  
GO:0005604basement membrane-IEA-  
GO:0005615extracellular space-IBA21873635  
GO:0005615extracellular space-IDA3903517  
GO:0005788endoplasmic reticulum lumen-TAS-  
GO:0031093platelet alpha granule lumen-TAS-  
GO:0070062extracellular exosome-HDA23533145  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-114608Platelet degranulation TAS
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-1474228Degradation of the extracellular matrixTAS
R-HSA-1474244Extracellular matrix organizationTAS
R-HSA-1592389Activation of Matrix MetalloproteinasesTAS
R-HSA-168256Immune SystemTAS
R-HSA-381426Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)TAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6783783Interleukin-10 signalingTAS
R-HSA-6785807Interleukin-4 and 13 signalingTAS
R-HSA-76002Platelet activation, signaling and aggregationTAS
R-HSA-76005Response to elevated platelet cytosolic Ca2+TAS
R-HSA-8957275Post-translational protein phosphorylationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26197083MMP, VEGF and TIMP as prognostic factors in recurring bladder cancer. (2015 Dec)Wieczorek EClin Biochem
9816309TIMP1 and adverse prognosis in non-small cell lung cancer. (1996 Aug)Fong KMClin Cancer Res
11479891Molecular genetics of small cell lung carcinoma. (2001 Apr)Wistuba IISemin Oncol
21514415Osteopontin modulates inflammation, mucin production, and gene expression signatures after inhalation of asbestos in a murine model of fibrosis. (2011 May)Sabo-Attwood TAm J Pathol
26846412Ancestry informative markers and selected single nucleotide polymorphisms in immunoregulatory genes on preterm labor and preterm premature rupture of membranes: a case control study. (2016 Feb 5)Ramos BRBMC Pregnancy Childbirth
29744169Inflammatory mediator polymorphisms associate with initial periodontitis in adolescents. (2016 Dec)Heikkinen AMClin Exp Dent Res
26306861Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects. (2015 Oct 14)Titz BJ Proteomics
22209925Metalloproteases/anti-metalloproteases imbalance in chronic obstructive pulmonary disease: genetic factors and treatment implications. (2011 Dec)Mocchegiani ECurr Opin Pulm Med
23146278Heavy smoking before coronary surgical procedures affects the native matrix metalloproteinase-2 and matrix metalloproteinase-9 gene expression in saphenous vein conduits. (2013 Jan)Yongxin SAnn Thorac Surg