Gene: TLR4

7099
ARMD10|CD284|TLR-4|TOLL
toll like receptor 4
protein-coding
9q33.1
Ensembl:ENSG00000136869 MIM:603030 Vega:OTTHUMG00000021046 UniprotKB:O00206
NG_011475.1
PubMed
CD|OD|ND|AD
95   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.641e-1 (AD)  3.648e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TRPS10.873
YAP10.87
SLC7A110.859
CDC14A0.855
ARHGAP310.855
FERMT20.854
NOTCH20.853
PPARA0.849
ITPR20.849
CYBRD10.848

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CRHBP-0.474
ABCC12-0.472
GALNT14-0.47
MCHR1-0.463
ADRA1D-0.454
RHO-0.45
MYOZ3-0.445
CYP26A1-0.444
PPEF1-0.442
TRABD2A-0.439

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01183NaloxoneSmall Molecule465-65-6ApprovedTarget
DB027673-Hydroxy-Myristic AcidSmall MoleculeExperimentalTarget
DB03017Lauric AcidSmall Molecule143-07-7Approved|ExperimentalTarget
DB04933EritoranSmall Molecule185955-34-4InvestigationalTarget
DB05475GolotimodSmall Molecule229305-39-9InvestigationalTarget
DB08231Myristic acidSmall Molecule544-63-8ExperimentalTarget
DB13615MifamurtideSmall Molecule838853-48-8Approved|ExperimentalTarget
ID Drug Name Action PubMed
C5348801,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane"1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA]"25406165
C0006039621-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one"1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [HMGB1 protein binds to LY96 protein binds to TLR4 protein]]"29111459
C0006039621-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one"1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [LY96 protein binds to TLR4 protein]]"28063877
C0006039621-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one"1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [LY96 protein binds to TLR4 protein binds to HMGB1 protein]]"28063877
C0006039621-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one"1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [NOX4 protein binds to LY96 protein binds to TLR4 protein]]"29111459
C47781915-deoxyprostaglandin J215-deoxyprostaglandin J2 inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 mRNA]24612634
C47781915-deoxyprostaglandin J215-deoxyprostaglandin J2 inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]24612634
C47781915-deoxyprostaglandin J215-deoxyprostaglandin J2 results in decreased expression of TLR4 protein17965732
C47781915-deoxyprostaglandin J2prolinedithiocarbamate promotes the reaction [15-deoxyprostaglandin J2 inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]]24612634
C44865917-(dimethylaminoethylamino)-17-demethoxygeldanamycin17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [morphine-3-glucuronide results in increased activity of TLR4 protein]19833175
C0534791-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine1-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine results in increased expression of TLR4 mRNA17515866
C0534791-O-hexadecyl-2-N-methylcarbamylphosphatidylcholineArachidonic Acid inhibits the reaction [1-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine results in increased expression of TLR4 mRNA]17515866
C0534791-O-hexadecyl-2-N-methylcarbamylphosphatidylcholineDocosahexaenoic Acids inhibits the reaction [1-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine results in increased expression of TLR4 mRNA]17515866
C4681141-palmitoyl-2-arachidonyl-3-phosphorylcholine1-palmitoyl-2-arachidonyl-3-phosphorylcholine metabolite results in decreased activity of TLR4 protein27020609
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one[Lipopolysaccharides co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] results in increased expression of TLR4 mRNA23405061
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [AGT protein results in increased expression of TLR4 protein]19451898
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-onerosiglitazone promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [AGT protein results in increased expression of TLR4 protein]]19451898
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 mRNA]]"24612634
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]]"24612634
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 2,4,5,2',5'-pentachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 2,4,5,2',5'-pentachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,5,2',5'-pentachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
C0098282,4,5,2',5'-pentachlorobiphenyl"2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
C04456324-hydroxycholesterol"[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA"24802026
C04456324-hydroxycholesterol24-hydroxycholesterol results in increased expression of TLR4 mRNA24802026
C04456324-hydroxycholesterol"Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA]"24802026
C04456324-hydroxycholesterolQuercetin analog inhibits the reaction [24-hydroxycholesterol results in increased expression of TLR4 mRNA]24802026
C04456324-hydroxycholesterol"Quercetin inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA]"24802026
C04456324-hydroxycholesterolQuercetin inhibits the reaction [24-hydroxycholesterol results in increased expression of TLR4 mRNA]24802026
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]23405061
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]]25171655
C07699627-hydroxycholesterol"[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA"24802026
C07699627-hydroxycholesterol27-hydroxycholesterol results in increased expression of TLR4 mRNA24802026
C07699627-hydroxycholesterol"Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA]"24802026
C07699627-hydroxycholesterolQuercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of TLR4 mRNA]24802026
C07699627-hydroxycholesterol"Quercetin inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA]"24802026
C07699627-hydroxycholesterolQuercetin inhibits the reaction [27-hydroxycholesterol results in increased expression of TLR4 mRNA]24802026
C0038982-anisidine2-anisidine affects the expression of TLR4 mRNA28089782
C5188602-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]"26443840
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl affects the expression of TLR4 mRNA"21703328
C0354193,4-dihydroxybenzohydroxamic acid"3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"25843059
C0354193,4-dihydroxybenzohydroxamic acid"3,4-dihydroxybenzohydroxamic acid results in decreased expression of TLR4 mRNA"25843059
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]22014880
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TLR4 mRNA"27188386
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal inhibits the reaction [TLR4 protein binds to TLR4 protein]19627980
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased activity of TLR4 protein19627980
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]19627980
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]19627980
C0275764-hydroxy-2-nonenalAcetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]19627980
C0275764-hydroxy-2-nonenalAcetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]19627980
C0275764-hydroxy-2-nonenalDithiothreitol inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]19627980
C0275764-hydroxy-2-nonenalDithiothreitol inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]19627980
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TLR4 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [A 769662 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]]"28096963
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol inhibits the reaction [Morphine results in increased expression of TLR4 protein]]"24756886
C5500919,10-dihydro-2,5-dimethoxyphenanthrene-1,7-diol"9,10-dihydro-2,5-dimethoxyphenanthrene-1,7-diol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of TLR4 protein]"20590609
C5500919,10-dihydro-2,5-dimethoxyphenanthrene-1,7-diol"9,10-dihydro-2,5-dimethoxyphenanthrene-1,7-diol inhibits the reaction [TLR4 protein results in increased secretion of TNF protein]"20590609
C512408A 769662"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [A 769662 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]]"28096963
C512408A 769662A 769662 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]28096963
D000082AcetaminophenAcetaminophen affects the expression of TLR4 mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of TLR4 protein26079055
D000082AcetaminophenChlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of TLR4 protein]26079055
D000082Acetaminophen[Ethanol co-treated with isopentyl alcohol] promotes the reaction [TLR4 results in increased susceptibility to Acetaminophen]16439473
D000082AcetaminophenTLR4 results in increased susceptibility to Acetaminophen16439473
D000085Acetates[Lipopolysaccharides results in decreased activity of TLR4 protein] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein]25053413
D000111AcetylcysteineAcetylcysteine results in decreased expression of TLR4 mRNA22385246
D000111AcetylcysteineAcetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]19627980
D000111AcetylcysteineAcetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]19627980
D000111AcetylcysteineAcetylcysteine inhibits the reaction [benzanthrone results in increased expression of TLR4 protein]28495615
D000111AcetylcysteineAcetylcysteine inhibits the reaction [iberin inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]25294874
D000119Acetylmuramyl-Alanyl-IsoglutamineAcetylmuramyl-Alanyl-Isoglutamine analog results in increased activity of TLR4 protein15905553
D000119Acetylmuramyl-Alanyl-IsoglutamineAcetylmuramyl-Alanyl-Isoglutamine analog results in increased activity of TLR4 protein15905553
D000119Acetylmuramyl-Alanyl-IsoglutamineTLR4 protein results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine analog15905553
D012794Sialic AcidsSialic Acids inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]24973090
C499366Active Hexose Correlated CompoundTLR4 protein affects the reaction [Active Hexose Correlated Compound results in increased secretion of CXCL8 protein]23194525
C499366Active Hexose Correlated CompoundTLR4 protein affects the reaction [Active Hexose Correlated Compound results in increased secretion of CCL2 protein]23194525
C499366Active Hexose Correlated CompoundTLR4 protein affects the reaction [Active Hexose Correlated Compound results in increased secretion of CXCL1 protein]23194525
D000241AdenosineAdenosine affects the localization of TLR4 protein21538184
D000241Adenosine"Adenosine promotes the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of TLR4 protein]"21538184
D000241AdenosineAdenosine results in increased expression of TLR4 mRNA21538184
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of TLR4 mRNA28943387
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of TLR4 mRNA22100608
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of TLR4 mRNA28789997
D000395Air Pollutants, Occupational"TLR4 protein affects the reaction [Air Pollutants, Occupational results in increased expression of IL10 protein]"25172162
D000395Air Pollutants, Occupational"TLR4 protein affects the reaction [Air Pollutants, Occupational results in increased expression of IL13 protein]"25172162
D000395Air Pollutants, Occupational"TLR4 protein affects the reaction [Air Pollutants, Occupational results in increased expression of IL33 protein]"25172162
D000395Air Pollutants, Occupational"TLR4 protein affects the reaction [Air Pollutants, Occupational results in increased expression of IL5 protein]"25172162
D000395Air Pollutants, Occupational"TLR4 protein affects the reaction [Air Pollutants, Occupational results in increased expression of MCPT1 protein]"25172162
D000395Air Pollutants, Occupational"TLR4 protein affects the reaction [Air Pollutants, Occupational results in increased expression of TSLP protein]"25172162
D013196Dihydrotestosteronebicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]]16317058
D013196DihydrotestosteroneDihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]16317058
D013196DihydrotestosteroneDihydrotestosterone inhibits the reaction [TNF protein results in increased expression of TLR4 mRNA]16317058
C545596alternaramidealternaramide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]26620692
C545596alternaramidealternaramide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]26620692
D000534Alum CompoundsTLR4 protein affects the reaction [Alum Compounds results in increased secretion of IL2 protein]22075093
D000534Alum CompoundsTLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [Alum Compounds results in increased secretion of IL2 protein]]22075093
D000534Alum CompoundsTLR4 protein affects the susceptibility to Alum Compounds22075093
D000534Alum CompoundsTLR4 protein affects the susceptibility to [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine co-treated with Alum Compounds]22075093
D000536Aluminum HydroxideTLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]22075093
D000536Aluminum HydroxideTLR4 protein affects the susceptibility to [Aluminum Hydroxide co-treated with Magnesium Hydroxide]22075093
D000536Aluminum HydroxideTLR4 protein affects the susceptibility to [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine]22075093
D0150752-Aminopurine2-Aminopurine inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]23405061
D000643Ammonium ChlorideAmmonium Chloride affects the expression of TLR4 mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of TLR4 mRNA24449571
D016718Arachidonic AcidArachidonic Acid inhibits the reaction [1-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine results in increased expression of TLR4 mRNA]17515866
D016718Arachidonic Acid[Docosahexaenoic Acids co-treated with Arachidonic Acid] affects the expression of TLR4 mRNA17515866
D001151ArsenicArsenic results in increased expression of TLR4 mRNA19945496|2783875
C015001arsenitearsenite results in decreased expression of TLR4 mRNA18191166
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]24239723
D001205Ascorbic Acid[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA23692848
D001205Ascorbic Acid[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein23692848
D001205Ascorbic AcidCAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]23692848
D001205Ascorbic AcidCAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]23692848
D001205Ascorbic Acid"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]"23692848
D001205Ascorbic Acid"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]"23692848
D000069059Atorvastatin Calcium[Atorvastatin Calcium co-treated with Enalapril] results in decreased expression of TLR4 mRNA20524934
D000069059Atorvastatin Calcium[Atorvastatin Calcium co-treated with Enalapril] results in decreased expression of TLR4 protein20524934
D000069059Atorvastatin Calcium[Atorvastatin Calcium co-treated with telmisartan] results in decreased expression of TLR4 mRNA20524934
D000069059Atorvastatin Calcium[Atorvastatin Calcium co-treated with telmisartan] results in decreased expression of TLR4 protein20524934
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased expression of TLR4 protein16387846
D000069059Atorvastatin CalciumAtorvastatin Calcium inhibits the reaction [Paraquat results in increased expression of TLR4 mRNA]27883937
D000069059Atorvastatin CalciumAtorvastatin Calcium inhibits the reaction [Paraquat results in increased expression of TLR4 protein]27883937
D000069059Atorvastatin CalciumAtorvastatin Calcium results in decreased expression of TLR4 mRNA27883937
D000069059Atorvastatin CalciumAtorvastatin Calcium results in decreased expression of TLR4 protein27883937
D001310AuranofinAuranofin inhibits the reaction [lipopolysaccharide A promotes the reaction [TLR4 protein binds to TLR4 protein]]17034761
D001379AzathioprineAzathioprine results in increased expression of TLR4 mRNA24184165
C057620bafilomycin ATLR4 protein affects the reaction [bafilomycin A promotes the reaction [Paraquat results in increased expression of MAP1LC3B protein]]27246695
C038044baicalinbaicalin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]24312512
C038044baicalinbaicalin results in decreased expression of TLR4 protein22019745
C044946benazeprilbenazepril results in decreased expression of TLR4 protein20981132
C012768benzanthroneAcetylcysteine inhibits the reaction [benzanthrone results in increased expression of TLR4 protein]28495615
C012768benzanthronebenzanthrone results in increased expression of TLR4 mRNA28495615
C012768benzanthronebenzanthrone results in increased expression of TLR4 protein28495615
C012768benzanthroneethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [benzanthrone results in increased expression of TLR4 protein]28495615
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TLR4 mRNA22228805
D001599BerberineBerberine inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]21963898
D004958Estradiol[bisphenol A co-treated with Estradiol] results in increased expression of TLR4 mRNA26496021
C002070betulinic acidbetulinic acid inhibits the reaction [TNF protein results in increased expression of TLR4 protein]22285267
C053541bicalutamidebicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]]16317058
C034786bis(4-hydroxycinnamoyl)methane[bis(4-hydroxycinnamoyl)methane analog co-treated with APP protein] results in increased expression of TLR4 mRNA22029407
C034786bis(4-hydroxycinnamoyl)methane[bis(4-hydroxycinnamoyl)methane co-treated with APP protein] results in increased expression of TLR4 mRNA22029407
C006780bisphenol Abisphenol A results in decreased expression of TLR4 mRNA26595511
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in increased expression of TLR4 mRNA26496021
C006780bisphenol Abisphenol A results in decreased expression of TLR4 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TLR4 mRNA28628672
D001786Blood Glucose[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of TLR4 protein27064547
D001786Blood Glucoseresveratrol inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of TLR4 protein]27064547
D000069286BortezomibBortezomib results in increased expression of TLR4 mRNA17895889
D019328Buthionine Sulfoximine[Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of TLR4 mRNA23986454
D019328Buthionine Sulfoximine[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of TLR4 protein26177832
D019328Buthionine Sulfoximinegadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of TLR4 protein]26177832
D020122tert-Butylhydroperoxide"1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [HMGB1 protein binds to LY96 protein binds to TLR4 protein]]"29111459
D020122tert-Butylhydroperoxide"1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [LY96 protein binds to TLR4 protein]]"28063877
D020122tert-Butylhydroperoxide"1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [LY96 protein binds to TLR4 protein binds to HMGB1 protein]]"28063877
D020122tert-Butylhydroperoxide"1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [NOX4 protein binds to LY96 protein binds to TLR4 protein]]"29111459
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide promotes the reaction [HMGB1 protein binds to LY96 protein binds to TLR4 protein]29111459
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide promotes the reaction [LY96 protein binds to TLR4 protein]28063877
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide promotes the reaction [LY96 protein binds to TLR4 protein binds to HMGB1 protein]28063877
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide promotes the reaction [NOX4 protein binds to LY96 protein binds to TLR4 protein]29111459
D002104CadmiumCadmium results in decreased expression of TLR4 mRNA24376830
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of TLR4 mRNA23741332
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TLR4 mRNA26352046
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TLR4 mRNA25993096|2928620
D000074262Canola OilCanola Oil metabolite results in decreased expression of TLR4 mRNA27363782
D002211CapsaicinCapsaicin results in increased expression of TLR4 protein22150557
D002211Capsaicin[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]22150557
D002211CapsaicinNaproxen inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]22150557
D002211CapsaicinSumatriptan inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]22150557
D002220CarbamazepineCarbamazepine results in increased expression of TLR4 mRNA22790970
D002233CarbocysteineCarbocysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]24076166|2426950
D002251Carbon Tetrachloride"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]"26443840
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of TLR4 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of TLR4 mRNA21291945|2644384
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of TLR4 protein21291945|2621827
D002251Carbon Tetrachlorideferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]21291945
D002251Carbon Tetrachlorideferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]21291945
D002251Carbon TetrachlorideQuercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]27601294
D002251Carbon TetrachlorideQuercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]26218279|2760129
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of TLR4 mRNA17504260|2268388
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of TLR4 protein17504260|2268388
D002251Carbon TetrachlorideChlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]23146752
D002251Carbon TetrachlorideChlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]23146752
D002251Carbon TetrachlorideCurcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]22683883
D002251Carbon TetrachlorideCurcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]22683883
D002251Carbon TetrachlorideLipopolysaccharides promotes the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]17504260
C054133casticincasticin results in decreased expression of TLR4 mRNA27862857
C078040catalpolcatalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TLR4 mRNA]23164921
D002392Catechin[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]26187476
C026690cerous chloridecerous chloride results in increased expression of TLR4 mRNA21656643
C026690cerous chloridecerous chloride results in increased expression of TLR4 protein21656643
D048271ChitosanChitosan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR4 mRNA]21329777
D048271ChitosanChitosan results in decreased expression of TLR4 mRNA21329777
D002726Chlorogenic AcidChlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of TLR4 protein]26079055
D002726Chlorogenic AcidChlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]23146752
D002726Chlorogenic AcidChlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]23146752
D004390ChlorpyrifosChlorpyrifos results in decreased expression of TLR425643018
D004390ChlorpyrifosChlorpyrifos results in increased expression of TLR4 protein26524701
C011724cholest-5-en-3 beta,7 alpha-diol"[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA"24802026
C011724cholest-5-en-3 beta,7 alpha-diol"cholest-5-en-3 beta,7 alpha-diol results in increased expression of TLR4 mRNA"24802026
C011724cholest-5-en-3 beta,7 alpha-diol"Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA]"24802026
C011724cholest-5-en-3 beta,7 alpha-diol"Quercetin inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA]"24802026
D002784Cholesterol[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of TLR4 mRNA26606054
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TLR4 mRNA20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TLR4 protein22915297
D002794CholineQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TLR4 protein]22915297
D002857ChromiumChromium results in decreased expression of TLR4 mRNA21437242
C012843cinnamic aldehydecinnamic aldehyde results in increased expression of TLR4 mRNA19524605
C012843cinnamic aldehydecinnamic aldehyde inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]17920563
C012843cinnamic aldehydecinnamic aldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]18306459
C000593591coagulin-Lcoagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]27568862
C007095cobaltiprotoporphyrin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]]25171655
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]24946281
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]25171655
C007095cobaltiprotoporphyrinNFE2L2 protein affects the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]]25171655
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [TLR4 protein binds to MYD88 protein]25780291
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [TLR4 protein binds to TICAM1 protein]25780291
C018021cobaltous chloridecobaltous chloride results in increased activity of [TLR4 protein binds to LY96 protein]25803856
C018021cobaltous chlorideTLR4 protein affects the reaction [cobaltous chloride results in increased secretion of CXCL8 protein]23692033
C018021cobaltous chloridecobaltous chloride results in increased expression of TLR4 mRNA24386269
C052387cocoa butter[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of TLR4 mRNA26606054
D003300Copper[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TLR4 mRNA25813056
D019327Copper SulfateTLR4 protein inhibits the reaction [Copper Sulfate results in increased secretion of CXCL8 protein]23692033
C408982CPG-oligonucleotideCPG-oligonucleotide results in decreased expression of TLR4 mRNA23405061
D003474CurcuminCurcumin inhibits the reaction [[Lipopolysaccharides binds to TLR4 protein] which results in increased activity of IRF3 protein]16678799
D003474CurcuminCurcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]16678799
D003474CurcuminCurcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]22683883
D003474CurcuminCurcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]22683883
D003474CurcuminCurcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]19002562
D003474CurcuminCurcumin results in decreased expression of TLR4 mRNA17965732
D003474CurcuminCurcumin results in decreased expression of TLR4 protein17965732
C038459curdlancurdlan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR4 mRNA]21329777
C038459curdlancurdlan results in decreased expression of TLR4 mRNA21329777
D016572CyclosporineCyclosporine results in increased expression of TLR4 mRNA27585667
D016572CyclosporineCyclosporine results in increased expression of TLR4 protein27585667
D016572Cyclosporineethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of TLR4 mRNA]27585667
D016572Cyclosporineethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of TLR4 protein]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of ATF3 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of CCL2 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of CCL5 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of COL1A2 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of CXCL10 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of DDIT3 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of ERN1 protein]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of FN1 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of HAVCR1 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of ICAM1 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of IL6 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of JUN protein modified form]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of LCN2 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of NFKBIA protein]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of SERPINE1 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of STAT3 protein]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of TGFB1 mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of TNFRSF12A mRNA]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of TNFRSF12A protein]27585667
D016572CyclosporineTLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of VCAM1 mRNA]27585667
C000596149cynatratoside-Ccynatratoside-C inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]29113806
D003630DaunorubicinTLR4 protein results in decreased susceptibility to Daunorubicin18789402
C014347decitabinedecitabine results in decreased methylation of TLR4 promoter23300844
C014347decitabinedecitabine results in increased expression of TLR4 mRNA23300844
D003676DeferoxamineDeferoxamine results in decreased expression of TLR4 protein24170104
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased expression of TLR4 mRNA27634381
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased expression of TLR4 protein27634381
D003687DehydroepiandrosteroneMetformin affects the reaction [Dehydroepiandrosterone results in increased expression of TLR4 protein]27634381
D003687DehydroepiandrosteroneMetformin inhibits the reaction [Dehydroepiandrosterone results in increased expression of TLR4 mRNA]27634381
D003687DehydroepiandrosteroneQuercetin affects the reaction [Dehydroepiandrosterone results in increased expression of TLR4 protein]27634381
D003687DehydroepiandrosteroneQuercetin inhibits the reaction [Dehydroepiandrosterone results in increased expression of TLR4 mRNA]27634381
D003703DemecolcineDemecolcine results in increased expression of TLR4 mRNA23649840
C007262deoxynivalenoldeoxynivalenol results in increased expression of TLR4 mRNA23922676
D003907DexamethasoneDexamethasone results in increased expression of TLR4 mRNA19853017
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TLR4 mRNA28628672
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]27568862
D016264Dextran SulfateDextran Sulfate results in increased expression of TLR4 protein21359540
D016264Dextran SulfateLipopolysaccharides inhibits the reaction [Dextran Sulfate results in increased expression of TLR4 protein]21359540
C042577diallyl trisulfidediallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]25500681
D003976DiazinonTLR4 protein mutant form results in increased susceptibility to Diazinon22428454
D003976Diazinon[TLR4 protein mutant form results in increased susceptibility to Diazinon] which results in decreased expression of BDNF mRNA22428454
D003976Diazinon[TLR4 protein mutant form results in increased susceptibility to Diazinon] which results in decreased expression of NGF mRNA22428454
D003976Diazinon[TLR4 protein mutant form results in increased susceptibility to Diazinon] which results in increased expression of BAX mRNA22428454
D002945CisplatinCisplatin results in increased expression of TLR4 mRNA27392435
D002945Cisplatin[Cisplatin co-treated with Lipopolysaccharides] results in increased expression of TLR4 protein21148032
D002945Cisplatin[Cisplatin promotes the reaction [Lipopolysaccharides binds to TLR4 protein]] which results in increased expression of IL1B protein21148032
D002945Cisplatin[Cisplatin promotes the reaction [Lipopolysaccharides binds to TLR4 protein]] which results in increased expression of IL6 protein21148032
D002945Cisplatin[Cisplatin promotes the reaction [Lipopolysaccharides binds to TLR4 protein]] which results in increased expression of TNF protein21148032
D002945Cisplatin[Cisplatin promotes the reaction [Lipopolysaccharides binds to TLR4 protein]] which results in increased phosphorylation of NFKBIA protein21148032
D002945CisplatinCisplatin results in increased expression of TLR4 mRNA21148032|2654657
D002945CisplatinCisplatin results in increased expression of TLR4 protein21148032
D002945CisplatinTLR4 protein promotes the reaction [[Cisplatin co-treated with Lipopolysaccharides] results in increased expression of TNF protein]21148032
D002945CisplatinCisplatin results in increased expression of TLR4 mRNA28371137
D002945CisplatinGrape Seed Proanthocyanidins inhibits the reaction [Cisplatin results in increased expression of TLR4 mRNA]28371137
C023635dienogestdienogest inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]22014880
D004041Dietary Fats[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA27769711
D004041Dietary FatsDietary Fats results in decreased expression of TLR4 mRNA18042831
D004041Dietary FatsDietary Fats results in increased expression of TLR4 mRNA23409006|2561471
D004041Dietary Fatsesculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA]27769711
D004041Dietary FatsQuercetin inhibits the reaction [Dietary Fats results in increased expression of TLR4 mRNA]25614714
D004041Dietary FatsDietary Fats results in increased expression of TLR4 mRNA22010203
D004041Dietary FatsTestosterone inhibits the reaction [Dietary Fats results in increased expression of TLR4 mRNA]22010203
C472511dimethylarsinous aciddimethylarsinous acid results in increased expression of TLR4 mRNA19945496
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of TLR4 mRNA25380136
C547156dimethylthioarsinic aciddimethylthioarsinic acid results in increased expression of TLR4 mRNA19945496
D004229DithiothreitolDithiothreitol inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]19627980
D004229DithiothreitolDithiothreitol inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]19627980
D004229DithiothreitolDithiothreitol inhibits the reaction [iberin inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]25294874
D004281Docosahexaenoic Acids[Docosahexaenoic Acids co-treated with Arachidonic Acid] affects the expression of TLR4 mRNA17515866
D004281Docosahexaenoic AcidsDocosahexaenoic Acids inhibits the reaction [1-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine results in increased expression of TLR4 mRNA]17515866
D004317DoxorubicinTLR4 protein affects the reaction [Doxorubicin results in decreased expression of GATA4 protein]18321777
D004317DoxorubicinTLR4 protein affects the reaction [Doxorubicin results in increased expression of EDN1 mRNA]18321777
D004317DoxorubicinTLR4 protein affects the reaction [Doxorubicin results in increased expression of EDN1 protein]18321777
D004317DoxorubicinTLR4 protein affects the susceptibility to Doxorubicin18321777
D004391DustTLR4 gene SNP affects the susceptibility to [Dust results in increased abundance of Endotoxins]28599265
D004391DustDust results in decreased expression of TLR4 mRNA22118940
D004391DustDust results in increased expression of TLR4 mRNA23281135
D004391DustTLR4 gene mutant form inhibits the reaction [Dust results in increased expression of CCL2 protein]26882889
D004391DustTLR4 gene mutant form inhibits the reaction [Dust results in increased expression of CCL3 protein]26882889
D004391DustTLR4 gene mutant form inhibits the reaction [Dust results in increased expression of [IL12A protein binds to IL12B protein]]26882889
D004391DustTLR4 gene mutant form inhibits the reaction [Dust results in increased expression of IL6 protein]26882889
D004391DustTLR4 gene mutant form inhibits the reaction [Dust results in increased expression of TNF protein]26882889
D004391DustTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL11 protein]26882889
D004391DustTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL2 protein]26882889
D004391DustTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
D004391DustTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL13 protein]26882889
D004391DustTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL4 protein]26882889
D004391DustTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
D004391DustVitamin D inhibits the reaction [Dust results in increased expression of TLR4 mRNA]23281135
C007590emulphogene BC 720emulphogene BC 720 results in increased expression of TLR4 mRNA25398874
D004656Enalapril[Atorvastatin Calcium co-treated with Enalapril] results in decreased expression of TLR4 mRNA20524934
D004656Enalapril[Atorvastatin Calcium co-treated with Enalapril] results in decreased expression of TLR4 protein20524934
D004731EndotoxinsTLR4 gene SNP affects the susceptibility to [Dust results in increased abundance of Endotoxins]28599265
D004731EndotoxinsTLR4 protein affects the susceptibility to Endotoxins16439473
C062669epicatechin gallate[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]26187476
C045651epigallocatechin gallate[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]26187476
C045651epigallocatechin gallateepigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR4 protein]27890776
C045651epigallocatechin gallateepigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR4 protein]27890776
D004917ErythromycinErythromycin results in increased expression of TLR4 mRNA27503388
D004917Erythromycin[Penicillin G co-treated with Erythromycin] results in increased expression of TLR4 mRNA27503388
C007628esculetinesculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA]27769711
D000431EthanolAscorbic Acid inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]24239723
D000431EthanolEthanol results in increased expression of TLR4 mRNA24239723
D000431EthanolSilymarin inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]24239723
D000431Ethanolcobaltiprotoporphyrin inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]24946281
D000431Ethanol[Ethanol co-treated with isopentyl alcohol] promotes the reaction [TLR4 results in increased susceptibility to Acetaminophen]16439473
D000431EthanolEthanol results in increased expression of TLR4 mRNA24946281
D000431Ethanol[Fructose co-treated with Ethanol] results in increased expression of TLR4 mRNA26858005
D000431EthanolTLR4 gene mutant form inhibits the reaction [Ethanol results in decreased expression of MAP2 protein]23500890
D000431EthanolTLR4 gene mutant form inhibits the reaction [Ethanol results in increased activity of CASP3 protein]23500890
D000431EthanolTLR4 gene mutant form inhibits the reaction [Ethanol results in increased expression of GFAP protein]23500890
D000431EthanolTLR4 gene mutant form inhibits the reaction [Ethanol results in increased expression of IL1B mRNA]23500890
D000431EthanolTLR4 gene mutant form inhibits the reaction [Ethanol results in increased expression of IL1B protein]23500890
D000431EthanolTLR4 gene mutant form inhibits the reaction [Ethanol results in increased expression of NOS2 protein]23500890
D000431EthanolTLR4 gene mutant form inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]23500890
D000431EthanolTLR4 gene mutant form inhibits the reaction [Ethanol results in increased expression of TNF mRNA]23500890
D000431EthanolTLR4 gene mutant form inhibits the reaction [Ethanol results in increased expression of TNF protein]23500890
D000431EthanolTLR4 results in increased susceptibility to Ethanol16439473
D000431EthanolADIPOQ protein inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]20861358
D000431EthanolEthanol results in increased expression of TLR4 mRNA20861358|2611588
D000431EthanolEthanol results in increased expression of TLR4 protein22525864
D000431EthanolPlant Extracts inhibits the reaction [Ethanol results in increased expression of TLR4 protein]22525864
D000431EthanolScopoletin inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]26115886
D000431EthanolSilymarin inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]26115886
C507035ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylateethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Paraquat results in increased expression of TLR4 protein]27890776
C507035ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylateethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [benzanthrone results in increased expression of TLR4 protein]28495615
C507035ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylateethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of TLR4 mRNA]27585667
C507035ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylateethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of TLR4 protein]27585667
C507035ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylateethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate results in decreased activity of TLR4 protein23958496
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in decreased expression of TLR4 mRNA23649840
D005054EugenolEugenol results in increased expression of TLR4 mRNA17936526
C020748ferrous sulfate[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA23692848
C020748ferrous sulfate[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein23692848
C020748ferrous sulfateCAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]23692848
C020748ferrous sulfateCAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]23692848
C020748ferrous sulfate"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]"23692848
C020748ferrous sulfate"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]"23692848
C004999ferulic acidferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]21291945
C004999ferulic acidferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]21291945
D005395Fish OilsFish Oils inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TLR4 mRNA]21653731
D005419FlavonoidsFlavonoids results in decreased expression of TLR4 mRNA18035473
D005466FluorocarbonsFluorocarbons inhibits the reaction [Lipopolysaccharides results in increased secretion of TLR4 mRNA]21933601
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TLR4 mRNA20938992
D005557FormaldehydeFormaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]25845602|2702060
D005632Fructose[Fructose co-treated with Ethanol] results in increased expression of TLR4 mRNA26858005
D005632Fructose[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TLR4 mRNA25813056
D062610Fungal PolysaccharidesFungal Polysaccharides binds to and affects the activity of TLR4 protein24447977
D062610Fungal PolysaccharidesTLR4 gene mutant form inhibits the reaction [Fungal Polysaccharides results in increased abundance of Nitric Oxide]22687552
D062610Fungal PolysaccharidesTLR4 gene mutant form inhibits the reaction [Fungal Polysaccharides results in increased expression of IL1B mRNA]22687552
D062610Fungal PolysaccharidesTLR4 gene mutant form inhibits the reaction [Fungal Polysaccharides results in increased expression of IL6 mRNA]22687552
D062610Fungal PolysaccharidesTLR4 gene mutant form inhibits the reaction [Fungal Polysaccharides results in increased expression of TNF mRNA]22687552
D062610Fungal PolysaccharidesTLR4 mutant form inhibits the reaction [Fungal Polysaccharides affects the localization of RELA protein]22687552
D062610Fungal Polysaccharides[TLR4 protein affects the abundance of Reactive Oxygen Species] affects the reaction [Fungal Polysaccharides results in increased secretion of TNF protein]24447977
D062610Fungal PolysaccharidesTLR4 protein affects the reaction [Fungal Polysaccharides results in increased chemical synthesis of Reactive Oxygen Species]24447977
D062610Fungal PolysaccharidesTLR4 protein affects the reaction [Fungal Polysaccharides results in increased secretion of TNF protein]24447977
D062610Fungal PolysaccharidesTLR4 protein affects the susceptibility to Fungal Polysaccharides24447977
C039281furanfuran results in increased expression of TLR4 mRNA27387713
C038958gadolinium chloride[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TLR4 mRNA25813056
C038958gadolinium chloridegadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of TLR4 protein]26177832
D005690Galactose"[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein"23535186
D005690Galactose"scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein]"23535186
C057580gallocatechol[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]26187476
C057580gallocatecholgallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]26187476
C021298ganglioside, GD1a"ganglioside, GD1a results in decreased expression of TLR4 protein"16651628
D005732GangliosidesGangliosides results in decreased expression of TLR4 protein16651628
D005732GangliosidesGangliosides results in decreased expression of TLR4 protein16651628
D005732GangliosidesTLR4 protein affects the reaction [Gangliosides results in increased expression of IL1B mRNA]16651628
D005732GangliosidesTLR4 protein affects the reaction [Gangliosides results in increased expression of TNF mRNA]16651628
D005732GangliosidesTLR4 protein promotes the reaction [Gangliosides results in increased expression of IL6 mRNA]16651628
C001277geldanamycingeldanamycin results in increased expression of TLR4 mRNA26705709
D019833GenisteinGenistein analog results in decreased expression of TLR4 protein25447760
C049864ginsenoside Reginsenoside Re inhibits the reaction [Lipopolysaccharides binds to TLR4 protein]22849695
D005947GlucoseGlucose results in decreased expression of TLR4 protein20200188
D005947Glucose"TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]"22558381
D005947Glucose"TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of MAFA mRNA]]"22558381
D005947Glucose"TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of PDX1 mRNA]]"22558381
C475739glutamyl-(2-(((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl)oxy)carbonyl)-3-((2-(1H-indol-3-yl)ethyl)amino)-3-oxopropyl)-cysteinyl-glycine sodium salt"glutamyl-(2-(((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl)oxy)carbonyl)-3-((2-(1H-indol-3-yl)ethyl)amino)-3-oxopropyl)-cysteinyl-glycine sodium salt inhibits the reaction [Lipopolysaccharides results in increased localization of TLR4 protein]"21276822
D005978GlutathioneGlutathione results in decreased expression of TLR4 mRNA22385246
D006034Glycyrrhetinic Acid"Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [TLR4 protein binds to LY96 protein]]"28213090
C511402Grape Seed ProanthocyanidinsGrape Seed Proanthocyanidins inhibits the reaction [Cisplatin results in increased expression of TLR4 mRNA]28371137
D006221HalothaneTLR4 protein affects the reaction [Halothane results in increased expression of IFNG protein]21245496
C001329helenalinhelenalin inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]16678799
D017313FenretinideFenretinide results in decreased expression of TLR4 mRNA28973697
D006820Hyaluronic Acid[Lipopolysaccharides results in decreased activity of TLR4 protein] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein]25053413
D006820Hyaluronic AcidHyaluronic Acid metabolite results in increased expression of TLR4 mRNA23692848
D006820Hyaluronic AcidHyaluronic Acid metabolite results in increased expression of TLR4 protein23692848
D006820Hyaluronic Acid"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR4 mRNA]"23692848
D006820Hyaluronic Acid"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR4 protein]"23692848
D006854HydrocortisoneHydrocortisone results in decreased expression of TLR4 mRNA17033190
C031927hydroquinonehydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]20054000
D006895Hydroxyethyl Starch DerivativesHydroxyethyl Starch Derivatives inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]21415432
C082585iberinAcetylcysteine inhibits the reaction [iberin inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]25294874
C082585iberinDithiothreitol inhibits the reaction [iberin inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]25294874
C082585iberiniberin analog binds to TLR4 protein25294874
C082585iberiniberin inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to MYD88 protein]]25294874
C082585iberiniberin inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR2 protein]]25294874
C082585iberiniberin inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]25294874
D007069IfosfamideIfosfamide results in increased expression of TLR4 mRNA25596134
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TLR4 mRNA28628672
D007213IndomethacinTLR4 protein affects the reaction [Indomethacin results in decreased activity of CYP1A2 protein]12927920
D007213IndomethacinTLR4 protein affects the reaction [Indomethacin results in decreased activity of CYP2D9 protein]12927920
D007213IndomethacinTLR4 protein affects the reaction [Indomethacin results in decreased activity of CYP3A11 protein]12927920
C051890irinotecanirinotecan results in increased expression of TLR4 protein28454924
C051890irinotecanSilymarin inhibits the reaction [irinotecan results in increased expression of TLR4 protein]28454924
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TLR4 mRNA28628672
C029683isopentyl alcohol[Ethanol co-treated with isopentyl alcohol] promotes the reaction [TLR4 results in increased susceptibility to Acetaminophen]16439473
D007545IsoproterenolIsoproterenol results in increased expression of TLR4 mRNA20003209
D007545IsoproterenolIsoproterenol results in increased expression of TLR4 mRNA24842192
D007545IsoproterenolMetformin inhibits the reaction [Isoproterenol results in increased expression of TLR4 mRNA]24842192
C544151jinfukangjinfukang results in decreased expression of TLR4 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of TLR4 mRNA26752646
C561695(+)-JQ1 compound[PD 0325901 co-treated with (+)-JQ1 compound] results in decreased expression of TLR4 mRNA25119042
C561695(+)-JQ1 compound"[(+)-JQ1 compound co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in decreased expression of TLR4 mRNA"24799421
C561695(+)-JQ1 compound"(+)-JQ1 compound inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]"24799421
C114999K-12 lipopolysaccharide[K-12 lipopolysaccharide binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL10 protein23266719
C114999K-12 lipopolysaccharide[K-12 lipopolysaccharide binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL6 protein23266719
C114999K-12 lipopolysaccharide[K-12 lipopolysaccharide binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein23266719
C114999K-12 lipopolysaccharide"Nanotubes, Carbon promotes the reaction [[K-12 lipopolysaccharide binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL6 protein]"23266719
C114999K-12 lipopolysaccharide"Nanotubes, Carbon promotes the reaction [[K-12 lipopolysaccharide binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein]"23266719
C114999K-12 lipopolysaccharideK-12 lipopolysaccharide binds to and results in increased activity of TLR4 protein23266719
C064309kaempferol 3-O-sophorosidekaempferol 3-O-sophoroside inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]22178603
D007649KetamineTLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]19540866
D007649KetamineTLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]19540866
D0151216-Ketoprostaglandin F1 alphaTLR4 mRNA affects the reaction [rosiglitazone inhibits the reaction [AGT protein results in decreased abundance of 6-Ketoprostaglandin F1 alpha]]19451898
C533150lancemaside Alancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]19956958
D008043Linseed OilLinseed Oil results in increased expression of TLR4 mRNA23409006
D008050Lipid ALipid A binds to and results in increased activity of TLR4 protein16299289
C040142lipid A precursors, bacterial"lipid A precursors, bacterial inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of [TLR4 protein binds to LY96 protein]]"25803856
C014643lipopeptidophosphoglycanCD14 protein promotes the reaction [lipopeptidophosphoglycan results in increased activity of TLR4 protein]15910421
C014643lipopeptidophosphoglycanlipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein15910421
C014643lipopeptidophosphoglycan[lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] results in increased activity of [NFKB1 protein binds to RELA protein]15910421
C014643lipopeptidophosphoglycan[lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of CXCL8 protein15910421
C014643lipopeptidophosphoglycan[lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL10 protein15910421
C014643lipopeptidophosphoglycan[lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein15910421
C014643lipopeptidophosphoglycan[lipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein15910421
C014643lipopeptidophosphoglycanlipopeptidophosphoglycan binds to and results in increased activity of TLR4 protein15910421
C014643lipopeptidophosphoglycanTLR4 protein results in increased susceptibility to lipopeptidophosphoglycan15910421
C082161lipopolysaccharide AAuranofin inhibits the reaction [lipopolysaccharide A promotes the reaction [TLR4 protein binds to TLR4 protein]]17034761
C433788lipopolysaccharide, E. coli O26-B6"Adenosine promotes the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of TLR4 protein]"21538184
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 affects the localization of TLR4 protein"21538184
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in decreased expression of TLR4 mRNA"23090859
C433788lipopolysaccharide, E. coli O26-B6"TLR4 protein affects the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of SELE mRNA]"27183587
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in increased expression of TLR4 protein"24211520
C433788lipopolysaccharide, E. coli O26-B6"schizandrol B inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TLR4 protein]"24211520
C433788lipopolysaccharide, E. coli O26-B6"TLR4 protein promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased abundance of Reactive Oxygen Species]"19735705
C433788lipopolysaccharide, E. coli O26-B6"TLR4 protein promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]"19735705
C433788lipopolysaccharide, E. coli O26-B6"TLR4 protein promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA]"19735705
C433788lipopolysaccharide, E. coli O26-B6"TLR4 protein results in increased susceptibility to lipopolysaccharide, E. coli O26-B6"19735705
C482199lipopolysaccharide, E coli O55-B5"[lipopolysaccharide, E coli O55-B5 co-treated with FSHB protein] results in decreased expression of TLR4 mRNA"22771338
C482199lipopolysaccharide, E coli O55-B5"9,10-dihydro-2,5-dimethoxyphenanthrene-1,7-diol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of TLR4 protein]"20590609
C482199lipopolysaccharide, E coli O55-B5"lipid A precursors, bacterial inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of [TLR4 protein binds to LY96 protein]]"25803856
C482199lipopolysaccharide, E coli O55-B5"[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL10 protein"23266719
C482199lipopolysaccharide, E coli O55-B5"[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein"23266719
C482199lipopolysaccharide, E coli O55-B5"[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL6 protein"23266719
C482199lipopolysaccharide, E coli O55-B5"[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein"23266719
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in decreased expression of TLR4 protein"17630318
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased activity of TLR4 protein"20590609
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased activity of [TLR4 protein binds to LY96 protein]"25803856
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 protein"19428938|2186541
C482199lipopolysaccharide, E coli O55-B5"Nanotubes, Carbon promotes the reaction [[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein]"23266719
C482199lipopolysaccharide, E coli O55-B5"Nanotubes, Carbon promotes the reaction [[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL6 protein]"23266719
C482199lipopolysaccharide, E coli O55-B5"Nanotubes, Carbon promotes the reaction [[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein]"23266719
C482199lipopolysaccharide, E coli O55-B5"TLR4 protein affects the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CXCL8 protein]"23692033
C482199lipopolysaccharide, E coli O55-B5"wogonoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 protein]"19428938
C482199lipopolysaccharide, E coli O55-B5"[Particulate Matter analog co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TLR4 mRNA"12832678
C482199lipopolysaccharide, E coli O55-B5"TLR4 gene mutant form inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of AHR mRNA]"24930766
C482199lipopolysaccharide, E coli O55-B5"TLR4 gene mutant form inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TDO2 mRNA]"24930766
C482199lipopolysaccharide, E coli O55-B5"[Vehicle Emissions analog co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TLR4 mRNA"12832678
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in decreased expression of TLR4 mRNA"19503810
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 mRNA"22693607
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein"23266719
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein"21767162|2629800
C440499lipopolysaccharide, Escherichia coli O111 B4"Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]"26298005
C440499lipopolysaccharide, Escherichia coli O111 B4"MitoTEMPO inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]"21767162
C440499lipopolysaccharide, Escherichia coli O111 B4"TLR4 protein affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA]"27183587
C440499lipopolysaccharide, Escherichia coli O111 B4"[TLR4 protein co-treated with LY96 protein co-treated with CD14 protein] results in increased susceptibility to lipopolysaccharide, Escherichia coli O111 B4"23680697
C440499lipopolysaccharide, Escherichia coli O111 B4"[[TLR4 protein co-treated with LY96 protein co-treated with CD14 protein] results in increased susceptibility to lipopolysaccharide, Escherichia coli O111 B4] which results in increased expression of CXCL8 mRNA"23680697
C440499lipopolysaccharide, Escherichia coli O111 B4"[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein"23535186
C440499lipopolysaccharide, Escherichia coli O111 B4"Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [TLR4 protein binds to LY96 protein]]"28213090
C440499lipopolysaccharide, Escherichia coli O111 B4"[(+)-JQ1 compound co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in decreased expression of TLR4 mRNA"24799421
C440499lipopolysaccharide, Escherichia coli O111 B4"(+)-JQ1 compound inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]"24799421
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein"24799421|2480239
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [TLR4 protein binds to LY96 protein]"28213090
C440499lipopolysaccharide, Escherichia coli O111 B4"resveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]"24802390
C440499lipopolysaccharide, Escherichia coli O111 B4"scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein]"23535186
C440499lipopolysaccharide, Escherichia coli O111 B4"TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]"22558381
C440499lipopolysaccharide, Escherichia coli O111 B4"TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of MAFA mRNA]]"22558381
C440499lipopolysaccharide, Escherichia coli O111 B4"TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of PDX1 mRNA]]"22558381
C440499lipopolysaccharide, Escherichia coli O111 B4"TLR4 results in increased susceptibility to lipopolysaccharide, Escherichia coli O111 B4"22558381
C440499lipopolysaccharide, Escherichia coli O111 B4"zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]"29289488
C440499lipopolysaccharide, Escherichia coli O111 B4"TLR4 protein affects the reaction [rosiglitazone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]]"19451898
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]22053092
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]22053092
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]22053092
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]21990308
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]22053092
D008070LipopolysaccharidesTLR4 protein binds to Lipopolysaccharides22053092
D008070Lipopolysaccharides[TLR4 protein binds to Lipopolysaccharides] which results in increased secretion of CXCL8 protein22053092
D008070Lipopolysaccharides[TLR4 protein binds to Lipopolysaccharides] which results in increased secretion of IL1B protein22053092
D008070Lipopolysaccharides[TLR4 protein binds to Lipopolysaccharides] which results in increased secretion of IL6 protein22053092
D008070Lipopolysaccharides2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]23405061
D008070Lipopolysaccharides2-Aminopurine inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]23405061
D008070LipopolysaccharidesLipopolysaccharides affects the expression of TLR4 mRNA19336472
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] results in increased expression of TLR4 mRNA23405061
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with pyrazolanthrone] results in increased expression of TLR4 mRNA23405061
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with SB 203580] results in increased expression of TLR4 mRNA23405061
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of TLR4 mRNA23405061
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR4 mRNA23405061
D008070LipopolysaccharidesN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]23405061
D008070LipopolysaccharidesSB 216763 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]23405061
D008070Lipopolysaccharides3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]22014880
D008070Lipopolysaccharidesbicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]]16317058
D008070LipopolysaccharidesChitosan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR4 mRNA]21329777
D008070Lipopolysaccharidescurdlan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR4 mRNA]21329777
D008070LipopolysaccharidesDDX58 protein affects the reaction [TLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]]27183587
D008070LipopolysaccharidesDDX58 protein affects the reaction [TLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]27183587
D008070LipopolysaccharidesDDX58 protein affects the reaction [TLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]]27183587
D008070LipopolysaccharidesDDX58 protein affects the reaction [TLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA]]27183587
D008070Lipopolysaccharidesdienogest inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]22014880
D008070LipopolysaccharidesDihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]16317058
D008070LipopolysaccharidesFluorocarbons inhibits the reaction [Lipopolysaccharides results in increased secretion of TLR4 mRNA]21933601
D008070LipopolysaccharidesLipopolysaccharides binds to and results in increased activity of TLR4 protein12734376
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of TNF mRNA24035785
D008070LipopolysaccharidesLipopolysaccharides binds to TLR4 protein22180778
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA22014880
D008070LipopolysaccharidesLipopolysaccharides inhibits the reaction [morphine-3-glucuronide results in increased activity of TLR4 protein]19833175
D008070LipopolysaccharidesLipopolysaccharides promotes the reaction [TLR4 protein binds to ARHGEF2 protein]22226621
D008070LipopolysaccharidesLipopolysaccharides results in decreased activity of TLR4 protein25053413
D008070Lipopolysaccharides[Lipopolysaccharides results in decreased activity of TLR4 protein] inhibits the reaction [[Hyaluronic Acid metabolite binds to Acetates] which results in increased secretion of IL1B protein]25053413
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of TLR4 mRNA21329777
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of TLR4 protein12176910|2097276
D008070LipopolysaccharidesLipopolysaccharides results in increased activity of TLR4 protein10835634|2125501
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR4 mRNA16317058|1644322
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR4 protein16443229|2193360
D008070Lipopolysaccharides[LY96 protein results in increased expression of TLR4 mRNA] which results in increased susceptibility to Lipopolysaccharides20700758
D008070Lipopolysaccharideslycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]22429818
D008070LipopolysaccharidesPolymyxin B inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]22014880
D008070LipopolysaccharidesProgesterone inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]22014880
D008070Lipopolysaccharides[Proteoglycans co-treated with Progesterone] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]22314502
D008070Lipopolysaccharides[resveratrol co-treated with [Lipopolysaccharides binds to and results in increased activity of TLR4 protein]] results in decreased secretion of IL10 protein24035785
D008070Lipopolysaccharides[resveratrol co-treated with [Lipopolysaccharides binds to and results in increased activity of TLR4 protein]] results in increased secretion of TNF protein24035785
D008070Lipopolysaccharidesresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]26497626
D008070Lipopolysaccharidesresveratrol promotes the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of TNF mRNA]24035785
D008070LipopolysaccharidesSimvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]16443229
D008070LipopolysaccharidesTLR4 affects the reaction [Lipopolysaccharides affects the localization of RELA protein]21616060
D008070LipopolysaccharidesTLR4 affects the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]21956143
D008070LipopolysaccharidesTLR4 affects the reaction [Lipopolysaccharides results in increased expression of VEGFA mRNA]22087807
D008070LipopolysaccharidesTLR4 affects the reaction [Lipopolysaccharides results in increased localization of HIF1A protein]22087807
D008070LipopolysaccharidesTLR4 mRNA promotes the reaction [Lipopolysaccharides results in decreased expression of CTH protein]29128401
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of CXCL8 protein]22014880
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased activity of RHOA]22226621
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of ARHGEF2 protein]22226621
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]22226621
D008070LipopolysaccharidesTLR4 protein affects the reaction [DDX58 protein affects the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]]27183587
D008070LipopolysaccharidesTLR4 protein affects the reaction [DDX58 protein affects the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]27183587
D008070LipopolysaccharidesTLR4 protein affects the reaction [DDX58 protein affects the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]]27183587
D008070LipopolysaccharidesTLR4 protein affects the reaction [DDX58 protein affects the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA]]27183587
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in decreased expression of LTC4S mRNA]12574384
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]27183587
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]27183587
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]27183587
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]24967690
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]24967690
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of SELE mRNA]27183587
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA]27183587
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]27183587
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]27183587
D008070LipopolysaccharidesTLR4 protein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]24967690
D008070LipopolysaccharidesTLR4 protein mutant form affects the susceptibility to Lipopolysaccharides10835634
D008070LipopolysaccharidesTLR4 protein promotes the reaction [Lipopolysaccharides results in increased expression of HRH1 mRNA]21255012
D008070LipopolysaccharidesTLR4 protein results in increased susceptibility to Lipopolysaccharides21383675
D008070LipopolysaccharidesZymosan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR4 mRNA]21329777
D008070Lipopolysaccharides"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 2,4,5,2',5'-pentachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
D008070Lipopolysaccharides"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
D008070Lipopolysaccharides"[2,4,5,2',5'-pentachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
D008070Lipopolysaccharides"2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
D008070Lipopolysaccharides2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]]25171655
D008070Lipopolysaccharides"3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"25843059
D008070Lipopolysaccharides4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]19627980
D008070Lipopolysaccharides4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]19627980
D008070Lipopolysaccharides"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [A 769662 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]]"28096963
D008070LipopolysaccharidesA 769662 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]28096963
D008070LipopolysaccharidesAcetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]19627980
D008070LipopolysaccharidesAcetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]19627980
D008070LipopolysaccharidesADIPOQ protein inhibits the reaction [[Lipopolysaccharides results in increased activity of TLR4 protein] which results in increased expression of CXCL10 mRNA]20861358
D008070LipopolysaccharidesADIPOQ protein inhibits the reaction [[Lipopolysaccharides results in increased activity of TLR4 protein] which results in increased expression of IFNB1 mRNA]20861358
D008070Lipopolysaccharidesalternaramide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]26620692
D008070Lipopolysaccharidesalternaramide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]26620692
D008070LipopolysaccharidesAPOA1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]20972769
D008070LipopolysaccharidesBerberine inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]21963898
D008070Lipopolysaccharidescatalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TLR4 mRNA]23164921
D008070Lipopolysaccharidescinnamic aldehyde inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]17920563
D008070Lipopolysaccharidescinnamic aldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]18306459
D008070Lipopolysaccharides[Cisplatin co-treated with Lipopolysaccharides] results in increased expression of TLR4 protein21148032
D008070Lipopolysaccharides[Cisplatin promotes the reaction [Lipopolysaccharides binds to TLR4 protein]] which results in increased expression of IL1B protein21148032
D008070Lipopolysaccharides[Cisplatin promotes the reaction [Lipopolysaccharides binds to TLR4 protein]] which results in increased expression of IL6 protein21148032
D008070Lipopolysaccharides[Cisplatin promotes the reaction [Lipopolysaccharides binds to TLR4 protein]] which results in increased expression of TNF protein21148032
D008070Lipopolysaccharides[Cisplatin promotes the reaction [Lipopolysaccharides binds to TLR4 protein]] which results in increased phosphorylation of NFKBIA protein21148032
D008070Lipopolysaccharidescoagulin-L inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]27568862
D008070Lipopolysaccharidescobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]25171655
D008070LipopolysaccharidesCurcumin inhibits the reaction [[Lipopolysaccharides binds to TLR4 protein] which results in increased activity of IRF3 protein]16678799
D008070LipopolysaccharidesCurcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]16678799
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]27568862
D008070Lipopolysaccharidesdiallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]25500681
D008070LipopolysaccharidesDithiothreitol inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]19627980
D008070LipopolysaccharidesDithiothreitol inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]19627980
D008070Lipopolysaccharidesginsenoside Re inhibits the reaction [Lipopolysaccharides binds to TLR4 protein]22849695
D008070Lipopolysaccharides"glutamyl-(2-(((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl)oxy)carbonyl)-3-((2-(1H-indol-3-yl)ethyl)amino)-3-oxopropyl)-cysteinyl-glycine sodium salt inhibits the reaction [Lipopolysaccharides results in increased localization of TLR4 protein]"21276822
D008070Lipopolysaccharideshelenalin inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]16678799
D008070LipopolysaccharidesHMOX1 protein inhibits the reaction [[Lipopolysaccharides results in increased activity of TLR4 protein] which results in increased expression of CXCL10 mRNA]20861358
D008070LipopolysaccharidesHMOX1 protein inhibits the reaction [[Lipopolysaccharides results in increased activity of TLR4 protein] which results in increased expression of IFNB1 mRNA]20861358
D008070Lipopolysaccharideshydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]20054000
D008070Lipopolysaccharides[IGF1 protein co-treated with Lipopolysaccharides] results in decreased expression of TLR4 mRNA21371294
D008070LipopolysaccharidesIL1RL1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]21352201
D008070LipopolysaccharidesIRAK2 protein promotes the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein results in decreased degradation of ZFP36 protein]]21291324
D008070LipopolysaccharidesLipopolysaccharides binds to and results in increased activity of TLR4 protein20861358
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] results in increased secretion of [IL12A protein binds to IL12B protein]21097750
D008070Lipopolysaccharides[[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PLAT mRNA21097750
D008070Lipopolysaccharides[[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in increased expression of IDO1 mRNA21097750
D008070Lipopolysaccharides[[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in increased expression of IDO2 mRNA21097750
D008070Lipopolysaccharides[[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in increased expression of TGFB1 mRNA21097750
D008070Lipopolysaccharides[[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in increased expression of TGFB3 mRNA21097750
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased activity of NFKB1 protein21097750
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased activity of NFKB2 protein21097750
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased activity of RELA protein21097750
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of CD86 protein21097750
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of CXCL10 mRNA20861358
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of ICAM1 protein21097750
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of IFNB1 mRNA20861358
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of ITGAX protein21097750
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL10 protein21097750
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL6 protein21097750
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein21097750
D008070LipopolysaccharidesLipopolysaccharides binds to TLR4 protein16678799|2114803
D008070Lipopolysaccharides[Lipopolysaccharides binds to TLR4 protein] which results in increased activity of IRF3 protein16678799
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TLR4 mRNA23164921
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Ozone] results in increased expression of TLR4 mRNA16864405
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of AKT1 protein22118570
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of NFKBIA protein22118570
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of STAT1 protein22118570
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of STAT3 protein22118570
D008070LipopolysaccharidesLipopolysaccharides inhibits the reaction [Dextran Sulfate results in increased expression of TLR4 protein]21359540
D008070LipopolysaccharidesLipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]16678799|1792056
D008070LipopolysaccharidesLipopolysaccharides promotes the reaction [TLR4 protein results in decreased degradation of ZFP36 protein]21291324
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of TLR4 mRNA25896969
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of TLR4 protein16651628|2589696
D008070LipopolysaccharidesLipopolysaccharides results in increased activity of TLR4 protein12848851|1962798
D008070Lipopolysaccharides[Lipopolysaccharides results in increased activity of TLR4 protein] which results in increased expression of CXCL10 mRNA20861358
D008070Lipopolysaccharides[Lipopolysaccharides results in increased activity of TLR4 protein] which results in increased expression of IFNB1 mRNA20861358
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR4 mRNA15665042|1686440
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR4 protein19433076|1954086
D008070LipopolysaccharidesLipopolysaccharides results in increased localization of TLR4 protein21276822
D008070LipopolysaccharidesNFE2L2 protein affects the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]]25171655
D008070LipopolysaccharidesPCB 180 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]26141388
D008070Lipopolysaccharides[picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]21371294
D008070LipopolysaccharidesPropofol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]19433076
D008070LipopolysaccharidesPropofol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]19433076
D008070Lipopolysaccharidesresveratrol inhibits the reaction [[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of AKT1 protein]22118570
D008070Lipopolysaccharidesresveratrol inhibits the reaction [[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of NFKBIA protein]22118570
D008070Lipopolysaccharidesresveratrol inhibits the reaction [[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of STAT1 protein]22118570
D008070Lipopolysaccharidesresveratrol inhibits the reaction [[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of STAT3 protein]22118570
D008070Lipopolysaccharidesresveratrol inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]22118570
D008070LipopolysaccharidesTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]21097750
D008070LipopolysaccharidesTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased activity of NFKB1 protein]21097750
D008070LipopolysaccharidesTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased activity of RELA protein]21097750
D008070LipopolysaccharidesTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of ITGAX protein]21097750
D008070LipopolysaccharidesTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL10 protein]21097750
D008070LipopolysaccharidesTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL6 protein]21097750
D008070LipopolysaccharidesTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein]21097750
D008070LipopolysaccharidesTetrachlorodibenzodioxin promotes the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased activity of NFKB2 protein]21097750
D008070LipopolysaccharidesTetrachlorodibenzodioxin promotes the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of CD86 protein]21097750
D008070LipopolysaccharidesTetrachlorodibenzodioxin promotes the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of ICAM1 protein]21097750
D008070LipopolysaccharidesTLR4 affects the reaction [Lipopolysaccharides affects the localization of and results in increased activity of GATA2 protein]23940812
D008070LipopolysaccharidesTLR4 affects the reaction [Lipopolysaccharides results in decreased expression of CLEC10A mRNA]17342418
D008070LipopolysaccharidesTLR4 affects the reaction [Lipopolysaccharides results in increased expression of MST1R mRNA]20453108
D008070LipopolysaccharidesTLR4 affects the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]22905218
D008070LipopolysaccharidesTLR4 gene mutant form affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]23000425
D008070Lipopolysaccharides[TLR4 gene mutant form co-treated with Lipopolysaccharides] results in increased expression of ALOX15 mRNA23000425
D008070LipopolysaccharidesTLR4 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of HMOX1 mRNA]23000425
D008070LipopolysaccharidesTLR4 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]22687552
D008070LipopolysaccharidesTLR4 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]22687552
D008070LipopolysaccharidesTLR4 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of PCNA]23000425
D008070LipopolysaccharidesTLR4 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES mRNA]23000425
D008070LipopolysaccharidesTLR4 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]23000425
D008070LipopolysaccharidesTLR4 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA]23000425
D008070LipopolysaccharidesTLR4 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]22687552
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]22687552
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased activity of HRAS protein]19540866
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]19540866
D008070LipopolysaccharidesTLR4 mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]19540866
D008070LipopolysaccharidesTLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]19540866
D008070LipopolysaccharidesTLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]19540866
D008070LipopolysaccharidesTLR4 mutant form promotes the reaction [Lipopolysaccharides results in increased expression of ADAM17]21874253
D008070LipopolysaccharidesTLR4 mutant form promotes the reaction [Lipopolysaccharides results in increased phosphorylation of EGFR protein]21874253
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in decreased expression of HFE2 mRNA]17255318
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]11123339
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of HAMP mRNA]17255318
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA]11123339
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]11123339
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of IRF8 mRNA]11123339
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]11123339
D008070LipopolysaccharidesTLR4 protein affects the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]11123339
D008070LipopolysaccharidesTLR4 protein affects the reaction [Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]19433076
D008070LipopolysaccharidesTLR4 protein affects the susceptibility to Lipopolysaccharides11581577
D008070LipopolysaccharidesTLR4 protein promotes the reaction [[Cisplatin co-treated with Lipopolysaccharides] results in increased expression of TNF protein]21148032
D008070LipopolysaccharidesTLR4 protein promotes the reaction [Lipopolysaccharides inhibits the reaction [TGFB1 protein results in increased expression of SMAD6 mRNA]]21295571
D008070LipopolysaccharidesTLR4 protein promotes the reaction [Lipopolysaccharides results in increased localization of and results in increased activity of RELA protein]22344225
D008070LipopolysaccharidesTLR4 protein promotes the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]21125213
D008070LipopolysaccharidesTLR4 protein promotes the reaction [Lipopolysaccharides results in increased phosphorylation of SMAD3 protein]21295571
D008070LipopolysaccharidesTLR4 protein results in increased susceptibility to Lipopolysaccharides23000425
D008070LipopolysaccharidesTLR4 results in decreased susceptibility to Lipopolysaccharides analog22039958
D008070Lipopolysaccharidesbaicalin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]24312512
D008070LipopolysaccharidesFormaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]25845602|2702060
D008070LipopolysaccharidesHydroxyethyl Starch Derivatives inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]21415432
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with sodium bisulfide] results in increased expression of TLR4 mRNA21910595
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with sodium bisulfide] results in increased expression of TLR4 protein21910595
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Titanium] results in decreased expression of TLR4 mRNA21308757
D008070LipopolysaccharidesLipopolysaccharides promotes the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]17504260
D008070LipopolysaccharidesLipopolysaccharides promotes the reaction [Oxygen deficiency results in increased expression of TLR4 mRNA]23082119
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of TLR4 mRNA16309824
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of TLR4 protein16651628
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR4 mRNA12575980|2119906
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR4 protein17504260|2210170
D008070Lipopolysaccharidesprolinedithiocarbamate inhibits the reaction [Lipopolysaccharides promotes the reaction [Oxygen deficiency results in increased expression of TLR4 mRNA]]23082119
D008070Lipopolysaccharidessalvianolic acid B inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]22101700
D008070Lipopolysaccharidessalvianolic acid B inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]22101700
D008070LipopolysaccharidesSialic Acids inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]24973090
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR4 mRNA15998543|2852874
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR4 protein28528741
D008070Lipopolysaccharidesochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]28528741
D008070Lipopolysaccharidesochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]28528741
D008070LipopolysaccharidesTLR4 protein affects the reaction [ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]]28528741
D008070LipopolysaccharidesTLR4 protein affects the reaction [ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]28528741
D008070LipopolysaccharidesAcetylcysteine inhibits the reaction [iberin inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]25294874
D008070LipopolysaccharidesCholecalciferol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4]28430709
D008070Lipopolysaccharidescynatratoside-C inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]29113806
D008070LipopolysaccharidesDithiothreitol inhibits the reaction [iberin inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]25294874
D008070Lipopolysaccharidesiberin inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to MYD88 protein]]25294874
D008070Lipopolysaccharidesiberin inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR2 protein]]25294874
D008070Lipopolysaccharidesiberin inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]25294874
D008070LipopolysaccharidesLipopolysaccharides binds to and results in increased activity of TLR4 protein15778123|1763019
D008070Lipopolysaccharides[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of NOS2 protein17630198
D008070LipopolysaccharidesLipopolysaccharides binds to TLR4 protein15851485
D008070LipopolysaccharidesLipopolysaccharides promotes the reaction [TLR4 protein binds to LY96 protein]21936536
D008070LipopolysaccharidesLipopolysaccharides promotes the reaction [TLR4 protein binds to MYD88 protein]25294874
D008070LipopolysaccharidesLipopolysaccharides results in increased activity of TLR4 protein25294874
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR428430709
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TLR4 protein29113806
D008070Lipopolysaccharidesphosphatidylinositol dimannoside analog inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to LY96 protein]]21936536
D008070LipopolysaccharidesQuercetin inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]25294874
D008070Lipopolysaccharidesspiraeoside analog inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]25294874
D008070Lipopolysaccharides[TNF protein co-treated with IL1B protein co-treated with IFNG protein co-treated with Lipopolysaccharides] results in increased expression of TLR4 mRNA20816778
C009900lipoteichoic acidlipoteichoic acid results in increased expression of TLR4 mRNA15998543
C009900lipoteichoic acidlipoteichoic acid binds to and affects the activity of TLR4 protein16373689
D019808LosartanLosartan inhibits the reaction [AGT protein results in increased expression of TLR4 protein]19451898
C015329lycopenelycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]22429818
C015329lycopenelycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]22429818
D008276Magnesium HydroxideTLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]22075093
D008276Magnesium HydroxideTLR4 protein affects the susceptibility to [Aluminum Hydroxide co-treated with Magnesium Hydroxide]22075093
D008276Magnesium HydroxideTLR4 protein affects the susceptibility to [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine]22075093
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TLR4 mRNA21641980
D008550MelatoninMelatonin inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TLR4 mRNA]28238930
D008550MelatoninMelatonin inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TLR4 protein]27413111|2823893
D008550MelatoninMelatonin inhibits the reaction [tetrachlorobenzoquinone results in increased localization of TLR4 protein]27413111
D008550MelatoninMelatonin inhibits the reaction [TLR4 protein promotes the reaction [MYD88 protein binds to LY96 protein binds to CD14 protein]]28238930
D008558MelphalanMelphalan results in decreased expression of TLR4 mRNA22363485
D008687MetforminMetformin affects the reaction [Dehydroepiandrosterone results in increased expression of TLR4 protein]27634381
D008687MetforminMetformin inhibits the reaction [Dehydroepiandrosterone results in increased expression of TLR4 mRNA]27634381
D008687MetforminMetformin inhibits the reaction [Isoproterenol results in increased expression of TLR4 mRNA]24842192
D008691MethadoneMethadone binds to TLR4 protein20178837
D008691MethadoneNaloxone affects the reaction [Methadone binds to TLR4 protein]20178837
D008691MethadoneMethadone affects the susceptibility to TLR4 protein20178837
D008691MethadoneMethadone results in increased expression of TLR4 mRNA20178837
D008691MethadoneMethadone results in increased expression of TLR4 protein20178837
D008713Methimazole[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of TLR4 protein26177832
D008713Methimazolegadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of TLR4 protein]26177832
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TLR4 mRNA20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TLR4 protein22915297
D008715MethionineQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TLR4 protein]22915297
D008727MethotrexateMethotrexate results in decreased expression of TLR4 mRNA17400583
D008727MethotrexateMethotrexate affects the expression of TLR4 mRNA18502557
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of TLR4 mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of TLR4 mRNA"26251327
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased expression of TLR4 mRNA15120970
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of TLR4 mRNA26881113
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of TLR4 protein26881113
D0156551-Methyl-4-phenylpyridiniumTLR4 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of IL1B protein]26881113
D0156551-Methyl-4-phenylpyridiniumTLR4 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of NOS2 protein]26881113
D0156551-Methyl-4-phenylpyridiniumTLR4 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of TNF protein]26881113
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA]"25406165
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA"25406165
D008779Methylthiouracil"Methylthiouracil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]"26298005
C555916MitoTEMPO"MitoTEMPO inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]"21767162
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]"23692848
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]"23692848
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR4 mRNA]"23692848
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of TLR4 protein]"23692848
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of TLR4 mRNA19945496
D005677G(M1) GangliosideG(M1) Ganglioside results in decreased expression of TLR4 protein16651628
D009020MorphineMorphine binds to TLR4 protein20178837
D009020MorphineNaloxone affects the reaction [Morphine binds to TLR4 protein]20178837
D009020Morphine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol inhibits the reaction [Morphine results in increased expression of TLR4 protein]]"24756886
D009020MorphineMorphine results in increased expression of TLR4 protein24756886
D009020Morphineresveratrol inhibits the reaction [Morphine results in increased expression of TLR4 protein]24756886
D009020MorphineMorphine affects the susceptibility to TLR4 protein20178837
D009020MorphineMorphine results in increased expression of TLR4 protein20178837
D009020MorphineMorphine results in increased activity of TLR4 protein19833175
C018108morphine-3-glucuronide17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [morphine-3-glucuronide results in increased activity of TLR4 protein]19833175
C018108morphine-3-glucuronideLipopolysaccharides inhibits the reaction [morphine-3-glucuronide results in increased activity of TLR4 protein]19833175
C018108morphine-3-glucuronidemorphine-3-glucuronide results in increased activity of TLR4 protein19833175
C018108morphine-3-glucuronidemorphine-3-glucuronide results in increased expression of TLR4 mRNA19833175
D009151Mustard GasMustard Gas results in increased expression of TLR4 mRNA18955075
D009151Mustard GasMustard Gas results in increased expression of TLR4 mRNA18988085
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]23405061
D009270NaloxoneNaloxone affects the reaction [Methadone binds to TLR4 protein]20178837
D009270NaloxoneNaloxone affects the reaction [Morphine binds to TLR4 protein]20178837
D037742Nanotubes, Carbon"Nanotubes, Carbon promotes the reaction [[K-12 lipopolysaccharide binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL6 protein]"23266719
D037742Nanotubes, Carbon"Nanotubes, Carbon promotes the reaction [[K-12 lipopolysaccharide binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein]"23266719
D037742Nanotubes, Carbon"Nanotubes, Carbon promotes the reaction [[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL12B protein]"23266719
D037742Nanotubes, Carbon"Nanotubes, Carbon promotes the reaction [[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL6 protein]"23266719
D037742Nanotubes, Carbon"Nanotubes, Carbon promotes the reaction [[lipopolysaccharide, E coli O55-B5 binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein]"23266719
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of TLR4 mRNA"25554681
D009288Naproxen[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]22150557
D009288NaproxenNaproxen inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]22150557
C022838nickel chloridenickel chloride results in increased activity of [TLR4 protein binds to LY96 protein]25803856
C022838nickel chlorideTLR4 protein affects the reaction [nickel chloride results in increased secretion of CXCL8 protein]23692033
C022838nickel chloridenickel chloride results in increased expression of TLR4 mRNA24670797
C022838nickel chlorideTLR4 mutant form inhibits the reaction [nickel chloride results in increased expression of TSLP protein]24670797
C029938nickel sulfatenickel sulfate results in increased expression of TLR4 protein26607348
C029938nickel sulfatepuerarin inhibits the reaction [nickel sulfate results in increased expression of TLR4 protein]26607348
D009569Nitric OxideTLR4 gene mutant form inhibits the reaction [Fungal Polysaccharides results in increased abundance of Nitric Oxide]22687552
D009569Nitric OxideTLR4 protein affects the reaction [Plant Extracts results in increased chemical synthesis of Nitric Oxide]23246459
D009569Nitric OxideTLR4 protein affects the reaction [Polysaccharides results in increased chemical synthesis of Nitric Oxide]23246459
C419410N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester"N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Oxygen deficiency results in increased expression of TLR4 mRNA]"24223152
C010615Nonidet P-40Nonidet P-40 results in decreased expression of TLR4 mRNA26552463
D017137NonoxynolNonoxynol results in increased expression of TLR4 mRNA25818602
C025256nonylphenolnonylphenol analog results in decreased expression of TLR4 mRNA25242005
C089665N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidineTLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [Alum Compounds results in increased secretion of IL2 protein]]22075093
C089665N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidineTLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]22075093
C089665N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidineTLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine results in increased expression of IL1B mRNA]22075093
C089665N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidineTLR4 protein affects the susceptibility to [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine]22075093
C089665N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidineTLR4 protein affects the susceptibility to [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine co-treated with Alum Compounds]22075093
C025589ochratoxin Aochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]28528741
C025589ochratoxin Aochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]28528741
C025589ochratoxin ATLR4 protein affects the reaction [ochratoxin A affects the expression of BCL2 mRNA]28528741
C025589ochratoxin ATLR4 protein affects the reaction [ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]]28528741
C025589ochratoxin ATLR4 protein affects the reaction [ochratoxin A promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]28528741
D010047OvalbuminTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL11 protein]26882889
D010047OvalbuminTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL2 protein]26882889
D010047OvalbuminTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of CCL7 protein]26882889
D010047OvalbuminTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL13 protein]26882889
D010047OvalbuminTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL4 protein]26882889
D010047OvalbuminTLR4 gene mutant form promotes the reaction [[Ovalbumin co-treated with Dust] results in increased expression of IL5 protein]26882889
C030110oxaliplatinTLR4 protein results in decreased susceptibility to oxaliplatin18789402
D010100OxygenLipopolysaccharides promotes the reaction [Oxygen deficiency results in increased expression of TLR4 mRNA]23082119
D010100Oxygen"N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Oxygen deficiency results in increased expression of TLR4 mRNA]"24223152
D010100Oxygen[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of TLR4 protein27064547
D010100Oxygen[Oxygen deficiency co-treated with Oxygen] results in increased expression of TLR4 mRNA27064547
D010100Oxygen[Oxygen deficiency co-treated with Oxygen] results in increased expression of TLR4 protein27064547
D010100OxygenOxygen deficiency results in increased expression of TLR4 mRNA23082119|2422315
D010100Oxygenprolinedithiocarbamate inhibits the reaction [Lipopolysaccharides promotes the reaction [Oxygen deficiency results in increased expression of TLR4 mRNA]]23082119
D010100Oxygenprolinedithiocarbamate inhibits the reaction [Oxygen deficiency results in increased expression of TLR4 mRNA]23082119
D010100Oxygenresveratrol inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of TLR4 protein]27064547
D010100Oxygenresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of TLR4 mRNA]27064547
D010100Oxygenresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of TLR4 protein]27064547
D010126Ozone[Lipopolysaccharides co-treated with Ozone] results in increased expression of TLR4 mRNA16864405
D010126OzoneOzone results in decreased expression of TLR4 mRNA mutant form11159012
D010126OzoneOzone results in increased expression of TLR4 mRNA11159012|1686440
D010126OzoneTLR4 gene mutant form inhibits the reaction [Ozone results in increased expression of CXCL1 mRNA]17626835
D010126OzoneTLR4 gene mutant form inhibits the reaction [Ozone results in increased expression of IL6 protein]17626835
D010126OzoneTLR4 gene mutant form results in decreased susceptibility to Ozone17626835
D010126OzoneTLR4 protein affects the reaction [Ozone results in increased expression of NOS2 mRNA]11159012
D010126OzoneTLR4 protein affects the susceptibility to Ozone22300504
D010126OzoneTLR4 protein mutant form results in decreased susceptibility to Ozone11159012
D010126OzoneTLR4 protein results in increased susceptibility to Ozone11159012
D010126OzoneTLR4 results in increased susceptibility to Ozone21543283
D017239PaclitaxelTLR4 protein affects the reaction [Paclitaxel results in increased expression of CXCL10 mRNA]11123339
D017239PaclitaxelTLR4 protein affects the reaction [Paclitaxel results in increased expression of IL12A mRNA]11123339
D017239PaclitaxelTLR4 protein affects the reaction [Paclitaxel results in increased expression of IL12B mRNA]11123339
D017239PaclitaxelTLR4 protein affects the reaction [Paclitaxel results in increased expression of IRF8 mRNA]11123339
D017239PaclitaxelTLR4 protein affects the reaction [Paclitaxel results in increased expression of PTGS2 mRNA]11123339
D017239PaclitaxelTLR4 protein affects the reaction [Paclitaxel results in increased expression of TNF mRNA]11123339
D017239PaclitaxelTLR4 protein affects the susceptibility to Paclitaxel11581577
D017239PaclitaxelTLR4 protein mutant form inhibits the reaction [Paclitaxel results in increased expression of CYP3A11 mRNA]28242239
D017239PaclitaxelTLR4 protein mutant form inhibits the reaction [Paclitaxel results in increased expression of CYP3A11 protein]28242239
D017239PaclitaxelTLR4 protein mutant form inhibits the reaction [Paclitaxel results in increased expression of IL6 mRNA]28242239
D017239PaclitaxelTLR4 protein mutant form inhibits the reaction [Paclitaxel results in increased expression of UGT1A1 mRNA]28242239
D017239PaclitaxelTLR4 protein mutant form inhibits the reaction [Paclitaxel results in increased expression of UGT1A1 protein]28242239
D017239PaclitaxelPaclitaxel binds to and affects the activity of TLR4 protein16373689
D019308Palmitic AcidPalmitic Acid results in increased expression of TLR4 mRNA25614714
D019308Palmitic AcidQuercetin inhibits the reaction [Palmitic Acid results in increased expression of TLR4 mRNA]25614714
D000073878Palm OilPalm Oil results in decreased expression of TLR4 mRNA18042831
C508075Pam(3)CSK(4) peptidePam(3)CSK(4) peptide results in decreased expression of TLR4 mRNA23405061
D010269Paraquatepigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR4 protein]27890776
D010269Paraquatethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Paraquat results in increased expression of TLR4 protein]27890776
D010269ParaquatParaquat results in increased expression of TLR4 protein27890776
D010269Paraquatepigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TLR4 protein]27890776
D010269ParaquatParaquat results in increased expression of TLR4 mRNA23969119
D010269ParaquatParaquat results in increased expression of TLR4 protein23969119|2789077
D010269ParaquatTLR4 gene mutant form inhibits the reaction [Paraquat results in increased expression of BAD protein]27442881
D010269ParaquatTLR4 gene mutant form inhibits the reaction [Paraquat results in increased expression of IL1B protein]23969119|2744288
D010269ParaquatTLR4 gene mutant form inhibits the reaction [Paraquat results in increased expression of TNF protein]23969119
D010269ParaquatTLR4 protein affects the reaction [bafilomycin A promotes the reaction [Paraquat results in increased expression of MAP1LC3B protein]]27246695
D010269ParaquatTLR4 protein affects the reaction [Paraquat results in decreased phosphorylation of MTOR protein]27246695
D010269ParaquatTLR4 protein affects the reaction [Paraquat results in decreased phosphorylation of ULK1 protein]27246695
D010269ParaquatTLR4 protein affects the reaction [Paraquat results in increased expression of ATG5 protein]27246695
D010269ParaquatTLR4 protein affects the reaction [Paraquat results in increased expression of ATG7 protein]27246695
D010269ParaquatTLR4 protein affects the reaction [Paraquat results in increased expression of MAP1LC3B protein]27246695
D010269ParaquatTLR4 protein affects the reaction [Paraquat results in increased expression of SQSTM1 protein]27246695
D010269ParaquatTLR4 results in increased susceptibility to Paraquat23969119
D010269ParaquatAtorvastatin Calcium inhibits the reaction [Paraquat results in increased expression of TLR4 mRNA]27883937
D010269ParaquatAtorvastatin Calcium inhibits the reaction [Paraquat results in increased expression of TLR4 protein]27883937
D010269ParaquatParaquat results in increased expression of TLR4 mRNA27883937
D010269ParaquatParaquat results in increased expression of TLR4 protein27883937
D052638Particulate MatterParticulate Matter results in decreased expression of TLR4 protein17630318
D052638Particulate Matter"[Particulate Matter analog co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TLR4 mRNA"12832678
D052638Particulate MatterParticulate Matter results in increased expression of TLR4 mRNA11991888
D052638Particulate MatterTLR4 gene mutant form inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]23896513
D052638Particulate MatterTLR4 gene mutant form inhibits the reaction [Particulate Matter results in increased secretion of CCL3 protein]23896513
D052638Particulate MatterTLR4 gene mutant form inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]23896513
D052638Particulate MatterTLR4 gene mutant form inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]23896513
D052638Particulate MatterTLR4 protein affects the reaction [Particulate Matter results in increased expression of CCL3 protein]16254717
D052638Particulate MatterTLR4 protein affects the reaction [Particulate Matter results in increased expression of CXCL1 protein]16254717
D052638Particulate MatterTLR4 protein affects the reaction [Particulate Matter results in increased expression of IL1B protein]16254717
C410127PCB 180"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 2,4,5,2',5'-pentachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
C410127PCB 180"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
C410127PCB 180"[2,4,5,2',5'-pentachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]"26141388
C410127PCB 180PCB 180 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]26141388
C506614PD 0325901[PD 0325901 co-treated with (+)-JQ1 compound] results in decreased expression of TLR4 mRNA25119042
C506614PD 0325901PD 0325901 results in decreased expression of TLR4 mRNA25119042
D010400Penicillin G[Penicillin G co-treated with Erythromycin] results in increased expression of TLR4 mRNA27503388
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TLR4 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of TLR4 mRNA26272509
D010672Phenytoin[Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of TLR4 mRNA23986454
D010672PhenytoinPhenytoin results in decreased expression of TLR4 mRNA23986454
C054977phosphatidylinositol dimannosideTLR4 gene mutant form inhibits the reaction [[phosphatidylinositol dimannoside analog co-treated with Thioglycolates] results in increased expression of IL6 protein]21936536
C054977phosphatidylinositol dimannosidephosphatidylinositol dimannoside analog inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to LY96 protein]]21936536
C030090phosphoramide mustardphosphoramide mustard results in increased expression of TLR4 mRNA27888070
D010844PicibanilTLR4 protein affects the susceptibility to Picibanil analog15289356
C415032picropodophyllin[picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]21371294
C415032picropodophyllinpicropodophyllin inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]21371294
C006253pirinixic acidpirinixic acid results in decreased expression of TLR4 mRNA16985257
D010936Plant ExtractsPlant Extracts binds to and affects the activity of TLR4 protein23108216
D010936Plant ExtractsPlant Extracts binds to and results in increased activity of TLR4 protein23246459
D010936Plant Extracts[Plant Extracts binds to and results in increased activity of TLR4 protein] affects the localization of [RELA protein binds to NFKB1 protein]23246459
D010936Plant ExtractsTLR4 protein affects the reaction [Plant Extracts results in increased chemical synthesis of Nitric Oxide]23246459
D010936Plant ExtractsPlant Extracts inhibits the reaction [Ethanol results in increased expression of TLR4 protein]22525864
D011070Poly I-CPoly I-C results in increased expression of TLR4 mRNA23405061
D011112Polymyxin BPolymyxin B inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]22014880
D011134PolysaccharidesPolysaccharides binds to and affects the activity of TLR4 protein23108216
D011134PolysaccharidesPolysaccharides binds to and results in increased activity of TLR4 protein23246459
D011134Polysaccharides[Polysaccharides binds to and results in increased activity of TLR4 protein] affects the localization of [RELA protein binds to NFKB1 protein]23246459
D011134PolysaccharidesTLR4 protein affects the reaction [Polysaccharides results in increased chemical synthesis of Nitric Oxide]23246459
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of TLR4 mRNA22714537
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of TLR4 mRNA19162173
D011339Probenecid"1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA]"25406165
D011339Probenecid"[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA"25406165
D011374ProgesteroneProgesterone inhibits the reaction [[Lipopolysaccharides co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]22014880
D011374ProgesteroneProgesterone results in increased expression of TLR4 mRNA17701593|2086464
D011374ProgesteroneProgesterone results in increased expression of TLR4 protein17701593
D011374Progesterone[Proteoglycans co-treated with Progesterone] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]22314502
D011374ProgesteroneProgesterone results in decreased activity of TLR4 protein22546503
C066229prolinedithiocarbamateprolinedithiocarbamate results in decreased expression of TLR4 protein27279714
C066229prolinedithiocarbamateQuercetin promotes the reaction [prolinedithiocarbamate results in decreased expression of TLR4 protein]27279714
C066229prolinedithiocarbamateprolinedithiocarbamate inhibits the reaction [Lipopolysaccharides promotes the reaction [Oxygen deficiency results in increased expression of TLR4 mRNA]]23082119
C066229prolinedithiocarbamateprolinedithiocarbamate inhibits the reaction [Oxygen deficiency results in increased expression of TLR4 mRNA]23082119
C066229prolinedithiocarbamateprolinedithiocarbamate inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]24612634
C066229prolinedithiocarbamateprolinedithiocarbamate promotes the reaction [15-deoxyprostaglandin J2 inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]]24612634
C066229prolinedithiocarbamateprolinedithiocarbamate promotes the reaction [rosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]]24612634
D015742PropofolPropofol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]19433076
D015742PropofolPropofol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]19433076
D015742PropofolTLR4 protein affects the reaction [Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]19433076
D011509Proteoglycans[Proteoglycans co-treated with Progesterone] inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]22314502
C033607puerarinpuerarin inhibits the reaction [nickel sulfate results in increased expression of TLR4 protein]26607348
C513428pyrachlostrobinpyrachlostrobin results in increased expression of TLR4 mRNA27029645
C432165pyrazolanthrone[Lipopolysaccharides co-treated with pyrazolanthrone] results in increased expression of TLR4 mRNA23405061
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of TLR4 mRNA"21152443
D011794Quercetin"Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA]"24802026
D011794QuercetinQuercetin analog inhibits the reaction [24-hydroxycholesterol results in increased expression of TLR4 mRNA]24802026
D011794QuercetinQuercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of TLR4 mRNA]24802026
D011794Quercetin"Quercetin inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA]"24802026
D011794QuercetinQuercetin inhibits the reaction [24-hydroxycholesterol results in increased expression of TLR4 mRNA]24802026
D011794QuercetinQuercetin inhibits the reaction [27-hydroxycholesterol results in increased expression of TLR4 mRNA]24802026
D011794QuercetinQuercetin promotes the reaction [prolinedithiocarbamate results in decreased expression of TLR4 protein]27279714
D011794QuercetinQuercetin promotes the reaction [TLR4 protein affects the expression of CDH1 protein]27279714
D011794QuercetinQuercetin promotes the reaction [TLR4 protein affects the expression of MMP2 protein]27279714
D011794QuercetinQuercetin promotes the reaction [TLR4 protein affects the expression of MMP9 protein]27279714
D011794QuercetinQuercetin promotes the reaction [TLR4 protein affects the expression of RELA protein]27279714
D011794QuercetinQuercetin promotes the reaction [TLR4 protein affects the expression of TLR4 protein]27279714
D011794QuercetinQuercetin results in decreased expression of TLR4 mRNA20828867
D011794QuercetinQuercetin results in decreased expression of TLR4 protein27279714
D011794QuercetinQuercetin results in increased expression of TLR4 mRNA21632981
D011794QuercetinQuercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]27601294
D011794QuercetinQuercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]26218279|2760129
D011794QuercetinQuercetin inhibits the reaction [Dietary Fats results in increased expression of TLR4 mRNA]25614714
D011794QuercetinQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TLR4 protein]22915297
D011794QuercetinQuercetin inhibits the reaction [Palmitic Acid results in increased expression of TLR4 mRNA]25614714
D011794QuercetinQuercetin affects the reaction [Dehydroepiandrosterone results in increased expression of TLR4 protein]27634381
D011794QuercetinQuercetin inhibits the reaction [Dehydroepiandrosterone results in increased expression of TLR4 mRNA]27634381
D011794QuercetinQuercetin inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]25294874
D017382Reactive Oxygen SpeciesTLR4 protein affects the abundance of Reactive Oxygen Species24447977
D017382Reactive Oxygen Species[TLR4 protein affects the abundance of Reactive Oxygen Species] affects the reaction [Fungal Polysaccharides results in increased secretion of TNF protein]24447977
D017382Reactive Oxygen SpeciesTLR4 protein affects the reaction [Fungal Polysaccharides results in increased chemical synthesis of Reactive Oxygen Species]24447977
D017382Reactive Oxygen Species"TLR4 protein promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased abundance of Reactive Oxygen Species]"19735705
C059514resveratrol[resveratrol co-treated with [Lipopolysaccharides binds to and results in increased activity of TLR4 protein]] results in decreased secretion of IL10 protein24035785
C059514resveratrol[resveratrol co-treated with [Lipopolysaccharides binds to and results in increased activity of TLR4 protein]] results in increased secretion of TNF protein24035785
C059514resveratrolresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]26497626
C059514resveratrolresveratrol promotes the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of TNF mRNA]24035785
C059514resveratrolresveratrol results in decreased activity of TLR4 protein24758933
C059514resveratrolresveratrol results in decreased expression of TLR422251620
C059514resveratrolresveratrol results in decreased expression of TLR4 protein24170104
C059514resveratrolTLR4 protein affects the susceptibility to resveratrol24758933
C059514resveratrol"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol inhibits the reaction [Morphine results in increased expression of TLR4 protein]]"24756886
C059514resveratrol"resveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]"24802390
C059514resveratrolresveratrol inhibits the reaction [[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of AKT1 protein]22118570
C059514resveratrolresveratrol inhibits the reaction [[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of NFKBIA protein]22118570
C059514resveratrolresveratrol inhibits the reaction [[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of STAT1 protein]22118570
C059514resveratrolresveratrol inhibits the reaction [[Lipopolysaccharides co-treated with TLR4] results in increased phosphorylation of STAT3 protein]22118570
C059514resveratrolresveratrol inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]22118570
C059514resveratrolresveratrol inhibits the reaction [Morphine results in increased expression of TLR4 protein]24756886
C059514resveratrolresveratrol results in decreased expression of TLR4 protein24818579
C059514resveratrolresveratrol inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of TLR4 protein]27064547
C059514resveratrolresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of TLR4 mRNA]27064547
C059514resveratrolresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of TLR4 protein]27064547
C059514resveratrolresveratrol results in decreased expression of TLR4 mRNA22246136
C059514resveratrolresveratrol results in decreased expression of TLR4 protein22246136|2693612
C059514resveratrolresveratrol inhibits the reaction [IL1B protein results in increased expression of TLR4 mRNA]24758933
C059514resveratrolresveratrol inhibits the reaction [IL1B protein results in increased expression of TLR4 protein]24758933
C059514resveratrol[resveratrol results in decreased activity of TLR4 protein] which results in decreased susceptibility to IL1B protein24758933
C059514resveratrolTLR4 protein affects the reaction [resveratrol inhibits the reaction [IL1B protein affects the localization of RELA protein]]24758933
C059514resveratrolTLR4 protein affects the reaction [resveratrol inhibits the reaction [IL1B protein results in increased expression of NFKB1 mRNA]]24758933
C059514resveratrolTLR4 protein affects the reaction [resveratrol results in decreased susceptibility to IL1B protein]24758933
C034206RibomunylTLR4 protein affects the reaction [Ribomunyl results in increased secretion of IL10 protein]16224278
C089730rosiglitazonerosiglitazone inhibits the reaction [AGT protein results in increased expression of TLR4 mRNA]19778788
C089730rosiglitazonerosiglitazone inhibits the reaction [AGT protein results in increased expression of TLR4 protein]19778788
C089730rosiglitazone"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 mRNA]]"24612634
C089730rosiglitazone"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]]"24612634
C089730rosiglitazoneprolinedithiocarbamate promotes the reaction [rosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]]24612634
C089730rosiglitazonerosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 mRNA]24612634
C089730rosiglitazonerosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]24612634
C089730rosiglitazone"TLR4 protein affects the reaction [rosiglitazone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]]"19451898
C089730rosiglitazonerosiglitazone inhibits the reaction [AGT protein results in increased expression of TLR4 mRNA]19451898
C089730rosiglitazonerosiglitazone inhibits the reaction [AGT protein results in increased expression of TLR4 protein]19451898
C089730rosiglitazonerosiglitazone promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [AGT protein results in increased expression of TLR4 protein]]19451898
C089730rosiglitazoneTLR4 mRNA affects the reaction [rosiglitazone inhibits the reaction [AGT protein results in decreased abundance of 6-Ketoprostaglandin F1 alpha]]19451898
C089730rosiglitazoneTLR4 mRNA affects the reaction [rosiglitazone inhibits the reaction [AGT protein results in increased expression of MMP9 protein]]19451898
C089730rosiglitazoneTLR4 mRNA affects the reaction [rosiglitazone inhibits the reaction [AGT protein results in increased expression of PPARG protein]]19451898
C089730rosiglitazoneTLR4 mRNA affects the reaction [rosiglitazone inhibits the reaction [AGT protein results in increased expression of TNF protein]]19451898
C089730rosiglitazoneTLR4 protein affects the reaction [rosiglitazone inhibits the reaction [AGT protein results in increased expression of TNF protein]]19451898
C041376rosmarinic acidrosmarinic acid results in decreased expression of TLR4 protein28789951
C076944salvianolic acid Bsalvianolic acid B inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]22101700
C076944salvianolic acid Bsalvianolic acid B inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]22101700
C093642SB 203580[Lipopolysaccharides co-treated with SB 203580] results in increased expression of TLR4 mRNA23405061
C417521SB 216763SB 216763 inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]23405061
C033585schizandrol B"schizandrol B inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TLR4 protein]"24211520
C018145scoparone"scoparone inhibits the reaction [[Galactose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein]"23535186
D012603ScopoletinScopoletin inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]26115886
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of TLR4 mRNA25895662
D012822Silicon DioxideSilicon Dioxide results in decreased expression of TLR4 mRNA19073995
D012838SilymarinSilymarin inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]24239723
D012838SilymarinSilymarin inhibits the reaction [irinotecan results in increased expression of TLR4 protein]28454924
D012838SilymarinSilymarin inhibits the reaction [Ethanol results in increased expression of TLR4 mRNA]26115886
D019821SimvastatinSimvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]16443229
D019821SimvastatinSimvastatin results in increased expression of TLR4 protein16387846
D019821SimvastatinSimvastatin results in decreased expression of TLR4 mRNA19166837
D019821SimvastatinSimvastatin results in decreased expression of TLR4 protein19166837
D012906SmokeSmoke results in increased expression of TLR4 mRNA21095227|2251675
C017947sodium arsenitesodium arsenite results in increased expression of TLR4 mRNA21134390
C025451sodium bisulfide[Lipopolysaccharides co-treated with sodium bisulfide] results in increased expression of TLR4 mRNA21910595
C025451sodium bisulfide[Lipopolysaccharides co-treated with sodium bisulfide] results in increased expression of TLR4 protein21910595
D020358Sodium Cholate[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of TLR4 mRNA26606054
C080613spiraeosidespiraeoside analog inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]25294874
D013311StreptozocinTNF protein inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]20446767
D013311Streptozocin[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA27769711
D013311Streptozocinesculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA]27769711
D013311StreptozocinStreptozocin results in increased expression of TLR4 mRNA20446767
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TLR4 mRNA21641980
D012460SulfasalazineSulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]19956958
C016766sulforafansulforafan results in increased expression of TLR4 mRNA26833863
D018170Sumatriptan[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]22150557
D018170SumatriptanSumatriptan inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]22150557
C490727T 91825T 91825 inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]28720485
C084178telmisartan[Atorvastatin Calcium co-treated with telmisartan] results in decreased expression of TLR4 mRNA20524934
C084178telmisartan[Atorvastatin Calcium co-treated with telmisartan] results in decreased expression of TLR4 protein20524934
D013739TestosteroneTestosterone inhibits the reaction [Dietary Fats results in increased expression of TLR4 mRNA]22010203
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of TLR4 mRNA28300664
C000591600tetrachlorobenzoquinonetetrachlorobenzoquinone results in increased expression of TLR4 mRNA27413111
C000591600tetrachlorobenzoquinonetetrachlorobenzoquinone results in increased expression of TLR4 protein27413111
C000591600tetrachlorobenzoquinoneTLR4 gene mutant form inhibits the reaction [tetrachlorobenzoquinone affects the localization of HMGB1 protein]27413111
C000591600tetrachlorobenzoquinoneTLR4 gene mutant form inhibits the reaction [tetrachlorobenzoquinone results in increased expression of HMGB1 mRNA]27413111
C000591600tetrachlorobenzoquinoneTLR4 gene mutant form inhibits the reaction [tetrachlorobenzoquinone results in increased expression of IL1B mRNA]27413111
C000591600tetrachlorobenzoquinoneTLR4 gene mutant form inhibits the reaction [tetrachlorobenzoquinone results in increased expression of IL6 mRNA]27413111
C000591600tetrachlorobenzoquinoneTLR4 gene mutant form inhibits the reaction [tetrachlorobenzoquinone results in increased expression of MYD88 mRNA]27413111
C000591600tetrachlorobenzoquinoneTLR4 gene mutant form inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TLR4 mRNA]27413111|2741311
C000591600tetrachlorobenzoquinoneTLR4 gene mutant form inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TNF mRNA]27413111
C000591600tetrachlorobenzoquinoneMelatonin inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TLR4 mRNA]28238930
C000591600tetrachlorobenzoquinoneMelatonin inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TLR4 protein]27413111|2823893
C000591600tetrachlorobenzoquinoneMelatonin inhibits the reaction [tetrachlorobenzoquinone results in increased localization of TLR4 protein]27413111
C000591600tetrachlorobenzoquinonetetrachlorobenzoquinone promotes the reaction [HMGB1 protein binds to TLR4 protein]27413111
C000591600tetrachlorobenzoquinonetetrachlorobenzoquinone results in increased expression of TLR4 mRNA27413111|2823893
C000591600tetrachlorobenzoquinonetetrachlorobenzoquinone results in increased expression of TLR4 protein27413111|2823893
C000591600tetrachlorobenzoquinonetetrachlorobenzoquinone results in increased localization of TLR4 protein27413111
D013749TetrachlorodibenzodioxinFish Oils inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TLR4 mRNA]21653731
D013749Tetrachlorodibenzodioxin[[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PLAT mRNA21097750
D013749Tetrachlorodibenzodioxin[[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in increased expression of IDO1 mRNA21097750
D013749Tetrachlorodibenzodioxin[[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in increased expression of IDO2 mRNA21097750
D013749Tetrachlorodibenzodioxin[[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in increased expression of TGFB1 mRNA21097750
D013749Tetrachlorodibenzodioxin[[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which co-treated with Tetrachlorodibenzodioxin] results in increased expression of TGFB3 mRNA21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of TLR4 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased activity of NFKB1 protein]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased activity of RELA protein]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of ITGAX protein]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL10 protein]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased secretion of IL6 protein]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased secretion of TNF protein]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased activity of NFKB2 protein]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of CD86 protein]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [[Lipopolysaccharides binds to and results in increased activity of TLR4 protein] which results in increased expression of ICAM1 protein]21097750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TLR4 mRNA21093581|2165373
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of TLR4 mRNA22298810
C030174tetrachloropalladiumTLR4 protein affects the reaction [tetrachloropalladium results in increased secretion of CXCL8 protein]23692033
D013755Tetradecanoylphorbol Acetate[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]26187476
D013755Tetradecanoylphorbol Acetategallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]26187476
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of TLR4 protein26187476|2872048
D013755Tetradecanoylphorbol AcetateTLR4 protein affects the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]23680697
D013755Tetradecanoylphorbol AcetateTLR4 protein affects the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein]23680697
D013864ThioglycolatesTLR4 gene mutant form inhibits the reaction [[phosphatidylinositol dimannoside analog co-treated with Thioglycolates] results in increased expression of IL6 protein]21936536
D014025TitaniumTitanium results in increased expression of TLR4 mRNA20682337
D014025Titanium[Lipopolysaccharides co-treated with Titanium] results in decreased expression of TLR4 mRNA21308757
D014028Tobacco Smoke PollutionCarbocysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]24076166|2426950
D014028Tobacco Smoke PollutionT 91825 inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]28720485
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TLR4 mRNA27865774
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of TLR4 mRNA27404394|2748027
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of TLR4 protein24076166|2418820
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TLR4 mRNA28111298
D014028Tobacco Smoke Pollution15-deoxyprostaglandin J2 inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 mRNA]24612634
D014028Tobacco Smoke Pollution15-deoxyprostaglandin J2 inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]24612634
D014028Tobacco Smoke Pollution"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 mRNA]]"24612634
D014028Tobacco Smoke Pollution"2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]]"24612634
D014028Tobacco Smoke Pollutionprolinedithiocarbamate inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]24612634
D014028Tobacco Smoke Pollutionprolinedithiocarbamate promotes the reaction [15-deoxyprostaglandin J2 inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]]24612634
D014028Tobacco Smoke Pollutionprolinedithiocarbamate promotes the reaction [rosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]]24612634
D014028Tobacco Smoke Pollutionrosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 mRNA]24612634
D014028Tobacco Smoke Pollutionrosiglitazone inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TLR4 protein]24612634
D014028Tobacco Smoke PollutionTLR4 protein promotes the reaction [Tobacco Smoke Pollution results in increased expression of and results in increased secretion of CXCL8 protein]24612634
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of TLR4 mRNA24188201|2461263
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of TLR4 protein24188201|2461263
D014212TretinoinTretinoin results in increased expression of TLR4 mRNA21934132
D014302Trinitrobenzenesulfonic Acidlancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]19956958
D014302Trinitrobenzenesulfonic AcidSulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]19956958
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of TLR420136961
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of TLR4 protein19597321|1995695
D014302Trinitrobenzenesulfonic AcidCurcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]19002562
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in decreased expression of TLR4 mRNA19998380
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of TLR416891783
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of TLR4 protein19002562
D010853Picryl ChlorideTLR2 protein affects the reaction [TLR4 protein results in increased susceptibility to Picryl Chloride]18725520
D010853Picryl ChlorideTLR4 protein results in increased susceptibility to Picryl Chloride18725520
C016481trisialoganglioside GT1trisialoganglioside GT1 results in decreased expression of TLR4 protein16651628
D014635Valproic AcidValproic Acid results in decreased expression of TLR4 mRNA23179753|2571616
D014635Valproic AcidValproic Acid results in decreased methylation of TLR4 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of TLR4 mRNA28001369
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of TLR4 protein17630318
D001335Vehicle EmissionsTLR4 protein affects the reaction [Vehicle Emissions results in increased expression of CCL3 protein]16254717
D001335Vehicle EmissionsTLR4 protein affects the reaction [Vehicle Emissions results in increased expression of CXCL1 protein]16254717
D001335Vehicle EmissionsTLR4 protein affects the reaction [Vehicle Emissions results in increased expression of IL1B protein]16254717
D001335Vehicle EmissionsVehicle Emissions affects the expression of TLR4 mRNA20362647
D001335Vehicle Emissions"[Vehicle Emissions analog co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TLR4 mRNA"12832678
D001335Vehicle EmissionsVehicle Emissions results in increased expression of TLR4 mRNA11991888
C025643vinclozolinvinclozolin results in increased expression of TLR4 mRNA18629315
D014800VitalliumTLR4 protein affects the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]23680697
D014800VitalliumTLR4 protein affects the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein]23680697
D014800Vitallium[TLR4 protein co-treated with LY96 protein co-treated with CD14 protein] results in increased susceptibility to Vitallium analog23680697
D014800Vitallium[[TLR4 protein co-treated with LY96 protein co-treated with CD14 protein] results in increased susceptibility to Vitallium analog] which results in increased expression of CXCL8 mRNA23680697
D014801Vitamin AVitamin A results in increased expression of TLR4 mRNA17033190
D014807Vitamin DVitamin D results in decreased expression of TLR4 mRNA23281135
D014807Vitamin DVitamin D results in decreased expression of TLR4 protein23281135
D014807Vitamin DVitamin D inhibits the reaction [Dust results in increased expression of TLR4 mRNA]23281135
D002762CholecalciferolCholecalciferol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4]28430709
C473995wogonoside"wogonoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 protein]"19428938
D015032ZincZinc deficiency results in increased expression of TLR4 mRNA19111725|2268992
D015034Zinc Oxide[Zinc Oxide analog co-treated with OVAL protein] results in increased expression of TLR4 protein25127755
D015034Zinc OxideZinc Oxide analog promotes the reaction [OVAL protein results in increased expression of TLR4 mRNA]25127755
C017803zinc protoporphyrinzinc protoporphyrin promotes the reaction [TLR4 protein binds to MYD88 protein]25780291
C013738zingerone"zingerone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein]"29289488
D015054ZymosanZymosan inhibits the reaction [Lipopolysaccharides results in decreased expression of TLR4 mRNA]21329777
D015054ZymosanZymosan results in decreased expression of TLR4 mRNA21329777
D015054ZymosanZymosan results in increased expression of TLR4 protein17321468

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0001530lipopolysaccharide binding-IBA21873635  
GO:0001530lipopolysaccharide binding-IMP16514062  
GO:0001530lipopolysaccharide binding-NAS10835634  
GO:0001875lipopolysaccharide receptor activity-IBA21873635  
GO:0001875lipopolysaccharide receptor activity-IDA19252480  
GO:0004888transmembrane signaling receptor activity-NAS11970998  
GO:0005102signaling receptor binding-IPI20037584  
GO:0005515protein binding-IPI11441107  11544529  12925853  15356101  16622205  17064675  
17126326  17258210  17803912  19252480  19509286  20037584  
20547845  21903422  25187624  29150600  
GO:0038023signaling receptor activity-TAS10426995  
GO:0042802identical protein binding-IPI23059983  23155421  
GO:0046982protein heterodimerization activity-IPI20037584  
GO ID GO Term Qualifier Evidence PubMed
GO:0000187activation of MAPK activity-ISS-  
GO:0002224toll-like receptor signaling pathway-IBA21873635  
GO:0002224toll-like receptor signaling pathway-TAS-  
GO:0002755MyD88-dependent toll-like receptor signaling pathway-ISS-  
GO:0002755MyD88-dependent toll-like receptor signaling pathway-TAS-  
GO:0002756MyD88-independent toll-like receptor signaling pathway-TAS-  
GO:0006954inflammatory response-IBA21873635  
GO:0006955immune response-TAS10426995  
GO:0007249I-kappaB kinase/NF-kappaB signaling-TAS-  
GO:0007252I-kappaB phosphorylation-IDA19740627  
GO:0010572positive regulation of platelet activation-ISS16514062  
GO:0010628positive regulation of gene expression-IMP23817958  
GO:0010628positive regulation of gene expression-ISS-  
GO:0016046detection of fungus-NAS11254600  
GO:0031663lipopolysaccharide-mediated signaling pathwayNOTIDA10880523  
GO:0031663lipopolysaccharide-mediated signaling pathway-IGI10880523  
GO:0032496response to lipopolysaccharide-IC16514062  
GO:0032496response to lipopolysaccharide-IDA12594207  
GO:0032497detection of lipopolysaccharide-IDA19252480  
GO:0032689negative regulation of interferon-gamma production-ISS-  
GO:0032700negative regulation of interleukin-17 production-ISS-  
GO:0032707negative regulation of interleukin-23 production-ISS-  
GO:0032715negative regulation of interleukin-6 production-ISS-  
GO:0032720negative regulation of tumor necrosis factor production-ISS-  
GO:0032722positive regulation of chemokine production-IDA19740627  
GO:0032727positive regulation of interferon-alpha production-ISS-  
GO:0032728positive regulation of interferon-beta production-ISS-  
GO:0032729positive regulation of interferon-gamma production-ISS-  
GO:0032732positive regulation of interleukin-1 production-ISS-  
GO:0032733positive regulation of interleukin-10 production-ISS-  
GO:0032735positive regulation of interleukin-12 production-ISS-  
GO:0032755positive regulation of interleukin-6 production-IDA19740627  
GO:0032757positive regulation of interleukin-8 production-IDA19740627  
GO:0032760positive regulation of tumor necrosis factor production-ISS-  
GO:0034128negative regulation of MyD88-independent toll-like receptor signaling pathway-TAS-  
GO:0034142toll-like receptor 4 signaling pathway-TAS-  
GO:0035666TRIF-dependent toll-like receptor signaling pathway-ISS-  
GO:0035666TRIF-dependent toll-like receptor signaling pathway-TAS-  
GO:0042088T-helper 1 type immune response-NAS11970998  
GO:0042116macrophage activation-IMP10835634  
GO:0042535positive regulation of tumor necrosis factor biosynthetic process-IDA17951129  
GO:0042742defense response to bacterium-TAS10426995  
GO:0043032positive regulation of macrophage activation-ISS-  
GO:0045084positive regulation of interleukin-12 biosynthetic process-IDA15027902  
GO:0045087innate immune response-TAS15356140  
GO:0045416positive regulation of interleukin-8 biosynthetic process-IDA17951129  
GO:0045429positive regulation of nitric oxide biosynthetic process-ISS-  
GO:0045671negative regulation of osteoclast differentiation-NAS12133979  
GO:0045944positive regulation of transcription by RNA polymerase II-ISS-  
GO:0050702interleukin-1 beta secretion-ISS-  
GO:0050718positive regulation of interleukin-1 beta secretion-IDA11432859  
GO:0050729positive regulation of inflammatory response-IC19740627  
GO:0050829defense response to Gram-negative bacterium-IBA21873635  
GO:0050829defense response to Gram-negative bacterium-IC16514062  
GO:0051092positive regulation of NF-kappaB transcription factor activity-IDA12594207  
GO:0051092positive regulation of NF-kappaB transcription factor activity-IGI20037584  
GO:0051770positive regulation of nitric-oxide synthase biosynthetic process-ISS-  
GO:0060729intestinal epithelial structure maintenance-ISS-  
GO:0070266necroptotic process-TAS-  
GO:0070373negative regulation of ERK1 and ERK2 cascade-ISS-  
GO:0071222cellular response to lipopolysaccharide-IDA11432859  
GO:0071222cellular response to lipopolysaccharide-ISS-  
GO:0071260cellular response to mechanical stimulus-IEP19593445  
GO:0071346cellular response to interferon-gamma-IDA11672593  
GO:0097190apoptotic signaling pathway-TAS-  
GO:0140052cellular response to oxidised low-density lipoprotein particle stimulus-ISS-  
GO:1900017positive regulation of cytokine production involved in inflammatory response-ISS-  
GO:1900227positive regulation of NLRP3 inflammasome complex assembly-ISS-  
GO:1901224positive regulation of NIK/NF-kappaB signaling-IDA19740627  
GO:1903223positive regulation of oxidative stress-induced neuron death-ISS-  
GO:1903428positive regulation of reactive oxygen species biosynthetic process-ISS-  
GO:1903974positive regulation of cellular response to macrophage colony-stimulating factor stimulus-IDA11672593  
GO:1904646cellular response to amyloid-beta-IGI20037584  
GO ID GO Term Qualifier Evidence PubMed
GO:0005622intracellular-IPI20037584  
GO:0005737cytoplasm-IDA19740627  
GO:0005769early endosome-IEA-  
GO:0005886plasma membrane-IDA16338228  19740627  
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-IBA21873635  
GO:0005887integral component of plasma membrane-IDA15027902  
GO:0009897external side of plasma membrane-IDA16514062  
GO:0009986cell surface-IDA25204797  
GO:0010008endosome membrane-TAS-  
GO:0031226intrinsic component of plasma membrane-IDA11274165  
GO:0043235receptor complex-IPI20037584  
GO:0046696lipopolysaccharide receptor complex-IDA11274165  19252480  
GO:0048471perinuclear region of cytoplasm-IDA15027902  
KEGG ID KEGG Term
hsa04145Phagosome
hsa04620Toll-like receptor signaling pathway
hsa05130Pathogenic Escherichia coli infection
hsa05140Leishmaniasis
hsa05142Chagas disease (American trypanosomiasis)
hsa05144Malaria
hsa05145Toxoplasmosis
hsa05146Amoebiasis
hsa05323Rheumatoid arthritis
Reactome ID Reactome Term Evidence
R-HSA-109581ApoptosisTAS
R-HSA-1236974ER-Phagosome pathwayTAS
R-HSA-1236975Antigen processing-Cross presentationTAS
R-HSA-1280218Adaptive Immune SystemTAS
R-HSA-140534Ligand-dependent caspase activationTAS
R-HSA-1643685DiseaseTAS
R-HSA-166016Toll Like Receptor 4 (TLR4) CascadeTAS
R-HSA-166058MyD88:Mal cascade initiated on plasma membraneTAS
R-HSA-166166MyD88-independent TLR4 cascade TAS
R-HSA-168138Toll Like Receptor 9 (TLR9) CascadeTAS
R-HSA-168164Toll Like Receptor 3 (TLR3) CascadeTAS
R-HSA-168179Toll Like Receptor TLR1:TLR2 CascadeTAS
R-HSA-168181Toll Like Receptor 7/8 (TLR7/8) CascadeTAS
R-HSA-168188Toll Like Receptor TLR6:TLR2 CascadeTAS
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-168898Toll-Like Receptors CascadesTAS
R-HSA-181438Toll Like Receptor 2 (TLR2) CascadeTAS
R-HSA-2562578TRIF-mediated programmed cell deathTAS
R-HSA-5260271Diseases of Immune SystemTAS
R-HSA-5357769Caspase activation via extrinsic apoptotic signalling pathwayTAS
R-HSA-5357801Programmed Cell DeathTAS
R-HSA-5602358Diseases associated with the TLR signaling cascadeTAS
R-HSA-5602498MyD88 deficiency (TLR2/4)TAS
R-HSA-5603041IRAK4 deficiency (TLR2/4)TAS
R-HSA-5686938Regulation of TLR by endogenous ligandTAS
R-HSA-9014325TICAM1,TRAF6-dependent induction of TAK1 complexTAS
R-HSA-936964Activation of IRF3/IRF7 mediated by TBK1/IKK epsilonTAS
R-HSA-937041IKK complex recruitment mediated by RIP1TAS
R-HSA-937061TRIF(TICAM1)-mediated TLR4 signaling TAS
R-HSA-937072TRAF6-mediated induction of TAK1 complex within TLR4 complexTAS
R-HSA-975138TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activationTAS
R-HSA-975155MyD88 dependent cascade initiated on endosomeTAS
R-HSA-975163IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulationTAS
R-HSA-983169Class I MHC mediated antigen processing & presentationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
15341923Gene polymorphisms in pro-inflammatory cytokines are associated with systemic inflammation in patients with severe periodontal infections. (2004 Oct 7)D'Aiuto FCytokine
19772581Association of the TLR4 Asp299Gly polymorphism with lung function in relation to body mass index. (2009 Sep 21)Pahwa PBMC Pulm Med
17982582Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward. (2007 Nov 2)Hutchinson MRScientificWorldJournal
21684332Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and induction of the inflammasome. (2011 Sep)Mortaz EBiochim Biophys Acta
24669857Nicotine exaggerates LPS-induced airway hyperreactivity via JNK-mediated up-regulation of Toll-like receptor 4. (2014 Sep)Xu YAm J Respir Cell Mol Biol
29113896Neuroinflammation produced by heavy alcohol intake is due to loops of interactions between Toll-like 4 and TNF receptors, peroxisome proliferator-activated receptors and the central melanocortin system: A novel hypothesis and new therapeutic avenues. (2018 Jan)Flores-Bastias ONeuropharmacology
28025440Toll-like receptor 4 polymorphism is associated with increased susceptibility to chronic obstructive pulmonary disease in Han Chinese patients with chronic periodontitis. (2016)Yu HJ Oral Sci
16246938CD14 and TLR4 gene polymorphisms in adult periodontitis. (2005 Nov)Laine MLJ Dent Res
26695754Neuroimmune Function and the Consequences of Alcohol Exposure. (2015)Crews FTAlcohol Res
16024933Genetic and environmental factors in monozygotic twins with Crohn's disease and their first-degree relatives: a case report. (2005)Vind IDigestion
21224062Chlamydia trachomatis infection increases fallopian tube PROKR2 via TLR2 and NFkappaB activation resulting in a microenvironment predisposed to ectopic pregnancy. (2011 Jan)Shaw JLAm J Pathol
23895427The cytokine mRNA increase induced by withdrawal from chronic ethanol in the sterile environment of brain is mediated by CRF and HMGB1 release. (2013 Dec)Whitman BAAlcohol Clin Exp Res
22431236Toll-like receptor 4 participates in the myelin disruptions associated with chronic alcohol abuse. (2012 May)Alfonso-Loeches SGlia
26704155[Effects of simvastatin on airway inflammation and airway mucus hypersecretion in rats with chronic obstructive pulmonary disease]. (2015 Jun 9)Wang SZhonghua Yi Xue Za Zhi
25644383DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. (2015 Dec)Northcutt ALMol Psychiatry
22994343Toll-like receptors 2, 3 and 4 and thymic stromal lymphopoietin expression in fatal asthma. (2012 Oct)Ferreira DSClin Exp Allergy
18034897Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke. (2007 Nov 22)MacRedmond RERespir Res
15770725Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: phenotype-genotype correlations. (2005 Mar 14)Lakatos PLWorld J Gastroenterol
21792899Toll-like receptor genes and their association with colon and rectal cancer development and prognosis. (2012 Jun 15)Slattery MLInt J Cancer
29744169Inflammatory mediator polymorphisms associate with initial periodontitis in adolescents. (2016 Dec)Heikkinen AMClin Exp Dent Res
26208141TLR2 and TLR4 Expression and Inflammatory Cytokines are Altered in the Airway Epithelium of Those with Alcohol Use Disorders. (2015 Sep)Bailey KLAlcohol Clin Exp Res
21193024Alcoholism and inflammation: neuroimmunology of behavioral and mood disorders. (2011 Jun)Kelley KWBrain Behav Immun
19140875The additive contribution from inflammatory genetic markers on the severity of cardiovascular disease. (2009 Jan)Berg KKScand J Immunol
21425908Toll-like receptor expression and activation in astroglia: differential regulation by HIV-1 Tat, gp120, and morphine. (2011)El-Hage NImmunol Invest
16870663Maternal smoking is associated with impaired neonatal toll-like-receptor-mediated immune responses. (2006 Oct)Noakes PSEur Respir J
21738617Bone marrow mononuclear cells up-regulate toll-like receptor expression and produce inflammatory mediators in response to cigarette smoke extract. (2011)Zhou JPLoS One
17872497Cigarette smoke exposure attenuates cytokine production by mouse alveolar macrophages. (2008 Feb)Gaschler GJAm J Respir Cell Mol Biol
28400259A role for the peripheral immune system in the development of alcohol use disorders? (2017 Aug 1)de Timary PNeuropharmacology
28813640Innate immune signaling in the ventral tegmental area contributes to drug-primed reinstatement of cocaine seeking. (2018 Jan)Brown KTBrain Behav Immun
25175868Neuroimmune basis of alcoholic brain damage. (2014)Crews FTInt Rev Neurobiol
27151970Evaluation of TLR4 Inhibitor, T5342126, in Modulation of Ethanol-Drinking Behavior in Alcohol-Dependent Mice. (2016 Sep)Bajo MAlcohol Alcohol
19080471[Expression of toll-like receptor 4 in human alveolar epithelial cells and its role in cellular inflammation]. (2008 Aug 5)Zhou MZhonghua Yi Xue Za Zhi
22251849The association of Toll-like receptor 4 gene polymorphisms with the development of emphysema in Japanese subjects: a case control study. (2012 Jan 18)Ito MBMC Res Notes
22999059Functional polymorphisms of Toll-like receptors 2 and 4 alter the risk for colorectal carcinoma in Europeans. (2013 Jan)Pimentel-Nunes PDig Liver Dis
27986929Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents. (2017 Feb 1)Harris RAJ Neurosci
26010811Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists. (2015 Jun 25)Selfridge BRJ Med Chem
21657944Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain. (2011 Jan-Feb)Alfonso-Loeches SCrit Rev Clin Lab Sci
25787746Mechanisms of neuroimmune gene induction in alcoholism. (2016 May)Crews FTPsychopharmacology (Berl)
26819423[Effect of aminophylline and simvastatin on airway inflammation and mucus hypersecretion in rats with chronic obstructive pulmonary disease]. (2016 Jan)Wang SZhong Nan Da Xue Xue Bao Yi Xue Ban
26485917[Effect of Yifei Jianpi Recipe on Airway Inflammation and Airway Mucus Hypersecretion of Chronic Obstructive Pulmonary Disease Model Rats]. (2015 Aug)Wang SZhongguo Zhong Xi Yi Jie He Za Zhi
19635922Concomitant inhalation of cigarette smoke and aerosolized protein activates airway dendritic cells and induces allergic airway inflammation in a TLR-independent way. (2009 Aug 15)Robays LJJ Immunol
23867237Increased receptor for advanced glycation end product expression in the human alcoholic prefrontal cortex is linked to adolescent drinking. (2013 Nov)Vetreno RPNeurobiol Dis
19811440TLR4 and IL-18 gene variants in chronic periodontitis: impact on disease susceptibility and severity. (2009)Noack BImmunol Invest
27622215Evaluating the immunogenicity of an intranasal vaccine against nicotine in mice using the Adjuvant Finlay Proteoliposome (AFPL1). (2016 Aug)Fraleigh NLHeliyon
25120286Can the TLR-4-mediated signaling pathway be "a key inflammatory promoter for sporadic TAA"? (2014)Ruvolo GMediators Inflamm
28537664Study on the expression of Toll-like receptor 4 and matrix metalloproteinase-9 in patients with chronic obstructive pulmonary disease and their clinical significance. (2017 May)Zhang YEur Rev Med Pharmacol Sci
27274225Effects of budesonide on toll-like receptor expression in alveolar macrophages from smokers with and without COPD. (2016)Ji JInt J Chron Obstruct Pulmon Dis
15576653Toll-like receptor 4 Asp299Gly gene polymorphism and risk of atherothrombosis. (2005 Jan)Zee RYStroke
26846412Ancestry informative markers and selected single nucleotide polymorphisms in immunoregulatory genes on preterm labor and preterm premature rupture of membranes: a case control study. (2016 Feb 5)Ramos BRBMC Pregnancy Childbirth
19675120Altered innate immune response in farmers and smokers. (2010 Feb)Sahlander KInnate Immun
16297172The immune responses to human and microbial heat shock proteins in periodontal disease with and without coronary heart disease. (2005 Dec)Hasan AClin Exp Immunol
23170858The association of down-regulated toll-like receptor 4 expression with airflow limitation and emphysema in smokers. (2012 Nov 21)Lee SWRespir Res
18763053Increased expression of Toll-like receptors 4 and 9 in human lung cancer. (2009 Jul)Zhang YBMol Biol Rep
24169336[Expression and significance of Toll-like receptor-4 in rats lung established by passive smoking or associated with intratracheal instillation of lipopolysaccharide]. (2013 Jul 23)Meng YZhonghua Yi Xue Za Zhi
17045043[Influence of lipopolysaccharide on the expression of Toll-like receptor 4 in human bronchial epithelium cell in patients with chronic obstructive pulmonary disease]. (2006 Jul)Li WZhonghua Jie He He Hu Xi Za Zhi
16844729Innate immune activation in neutrophilic asthma and bronchiectasis. (2007 Mar)Simpson JLThorax
19929430Gender-related tumor necrosis factor-alpha responses in naive volunteers with Toll-like receptor 4 polymorphisms exposed in a swine confinement facility. (2009 Dec)Senthilselvan AJ Interferon Cytokine Res
28893037Periodontal Initial Radiological Findings of Genetically Predisposed Finnish Adolescents. (2017 Jul)Heikkinen AMJ Clin Diagn Res
29066918Asthma with bronchial hypersecretion: expression of mucins and toll-like receptors in sputum and blood. (2017)Crespo-Lessmann AJ Asthma Allergy
27472367Stress and Withdrawal from Chronic Ethanol Induce Selective Changes in Neuroimmune mRNAs in Differing Brain Sites. (2016 Jul 27)Knapp DJBrain Sci
25332681Diet and lifestyle factors modify immune/inflammation response genes to alter breast cancer risk and prognosis: the Breast Cancer Health Disparities Study. (2014 Dec)Slattery MLMutat Res
19679181Evidence that opioids may have toll-like receptor 4 and MD-2 effects. (2010 Jan)Hutchinson MRBrain Behav Immun
18928988Maternal and fetal Toll-like receptor 4 genotype and chorionic plate inflammatory lesions. (2008 Oct)Simhan HNAm J Obstet Gynecol
20980751Toll-like receptor 4 immunohistochemical expression is enhanced in macrophages of symptomatic carotid atherosclerotic plaques. (2011)Katsargyris ACerebrovasc Dis
21439805Toll-like receptor expression in smokers with and without COPD. (2011 Aug)von Scheele IRespir Med
29649455Serum Toll-like receptor 4: A novel and promising biomarker for identification of aortic aneurysmal diseases. (2018 Apr 9)Li TClin Chim Acta
24376840GroEL1, a heat shock protein 60 of Chlamydia pneumoniae, impairs neovascularization by decreasing endothelial progenitor cell function. (2013)Lin YWPLoS One
23349936Determinants of serum concentrations of lipopolysaccharide-binding protein (LBP) in the adult population: the role of obesity. (2013)Gonzalez-Quintela APLoS One
24269501Oxidative stress and innate immunity responses in cigarette smoke stimulated nasal epithelial cells. (2014 Mar)Pace EToxicol In Vitro
23348232Toll-like receptor 3 stimulation causes corticosteroid-refractory airway neutrophilia and hyperresponsiveness in mice. (2013 Jul)Kimura GChest
24551070Release of neuronal HMGB1 by ethanol through decreased HDAC activity activates brain neuroimmune signaling. (2014)Zou JYPLoS One
23055738Epidemiologic and molecular pathophysiology of chronic opioid dependence and the place of naltrexone extended-release formulations in its clinical management. (2012)Reece ASSubst Abuse
23476107Cigarette smoke suppresses the surface expression of c-kit and FcepsilonRI on mast cells. (2013)Givi MEMediators Inflamm
18983635TLR4 and IL-18 gene variants in aggressive periodontitis. (2008 Dec)Noack BJ Clin Periodontol
26043790Cocaine-mediated microglial activation involves the ER stress-autophagy axis. (2015)Guo MLAutophagy
23206318High mobility group box 1/Toll-like receptor danger signaling increases brain neuroimmune activation in alcohol dependence. (2013 Apr 1)Crews FTBiol Psychiatry
28956832Multiple Gene-Environment Interactions on the Angiogenesis Gene-Pathway Impact Rectal Cancer Risk and Survival. (2017 Sep 28)Sharafeldin NInt J Environ Res Public Health
24454004Effects of polymorphisms of innate immunity genes and environmental factors on the risk of noncardia gastric cancer. (2013 Dec)Kim JCancer Res Treat
15302104Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction. (2004 Aug)Edfeldt KEur Heart J
21447380Naloxone-precipitated morphine withdrawal behavior and brain IL-1beta expression: comparison of different mouse strains. (2011 Aug)Liu LBrain Behav Immun
17332447Toll receptor polymorphisms and carotid artery intima-media thickness. (2007 Apr)Labrum RStroke
16219455Association of the ASP299GLY TLR4 polymorphism with COPD. (2006 May)Rohde GRespir Med
19786742Disease behavior in adult patients: are there predictors for stricture or fistula formation? (2009)Dotan IDig Dis
24612634PPARgamma agonists regulate tobacco smoke-induced Toll like receptor 4 expression in alveolar macrophages. (2014 Mar 11)Yin YRespir Res
29566963Analysis of the relationship between interleukin polymorphisms within miRNA-binding regions and alcoholic liver disease. (2018 May)Novo-Veleiro IRev Clin Esp
22878868Nicotine treatment improves Toll-like receptor 2 and Toll-like receptor 9 responsiveness in active pulmonary sarcoidosis. (2013 Feb 1)Julian MWChest
27397760Effects of ceftaroline on the innate immune and on the inflammatory responses of bronchial epithelial cells exposed to cigarette smoke. (2016 Sep 6)Pace EToxicol Lett
19046305Impact of genetic variants of CD14 and TLR4 on subgingival periodontopathogens. (2008 Dec)Schulz SInt J Immunogenet
24453429S100A8 and S100A9: DAMPs at the crossroads between innate immunity, traditional risk factors, and cardiovascular disease. (2013)Schiopu AMediators Inflamm
22343073Alterations of plasma inflammatory biomarkers in the healthy and chronic obstructive pulmonary disease patients with or without acute exacerbation. (2012 Jun 6)Chen HJ Proteomics
24776844Associations between functional polymorphisms in the NFkappaB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease. (2014 Dec)Bank SPharmacogenomics J
27187237TLR4 signaling in VTA dopaminergic neurons regulates impulsivity through tyrosine hydroxylase modulation. (2016 May 17)Aurelian LTransl Psychiatry
26617606Cigarette Smoke Amplifies Inflammatory Response and Atherosclerosis Progression Through Activation of the H1R-TLR2/4-COX2 Axis. (2015)Barua RSFront Immunol
23239997Functional characterization of TLR4 +3725 G/C polymorphism and association with protection against overweight. (2012)Penas-Steinhardt APLoS One
24121451Role of phosphodiesterase inhibitor Ibudilast in morphine-induced hippocampal injury. (2014 Jul)Zhaleh MJ Inj Violence Res