Gene: TNFAIP6

7130
TSG-6|TSG6
TNF alpha induced protein 6
protein-coding
2q23.3
Ensembl:ENSG00000123610 MIM:600410 Vega:OTTHUMG00000131884 UniprotKB:P98066
NC_000002.12
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.210e-1 (AD)  2.003e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SPSB10.749
ADA0.738
NGFR0.723
GLIPR20.719
CLIC40.712
GDNF0.712
CDH190.709
TNFRSF12A0.704
RHOG0.701
EFNA10.701

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KCNQ4-0.497
SCRT1-0.476
DBH-0.454
SYT15-0.441
NKX6-3-0.437
CDH22-0.431
ANK1-0.431
GRIP2-0.414
CUX2-0.406
BEAN1-0.396

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB08818Hyaluronic acidSmall Molecule9004-61-9ApprovedTarget
ID Drug Name Action PubMed
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in increased expression of TNFAIP6 mRNA28329830
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of TNFAIP6 mRNA"19114083
C0131862,3-pentanedione"2,3-pentanedione results in increased expression of TNFAIP6 mRNA"25710175
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in increased expression of TNFAIP6 mRNA"20406850
C0020104-(2-aminoethyl)benzenesulfonylfluoride4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA]20660070
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased activity of [SMAD2 protein co-treated with SMAD3 protein]] inhibits the reaction [FSHB protein results in increased expression of TNFAIP6 mRNA]"21520325
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNFAIP6 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNFAIP6 mRNA"27188386
C0343434-aminobenzhydrazide4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of TNFAIP6 mRNA]24530881
C0297284-phenylenediamine4-phenylenediamine results in increased expression of TNFAIP6 mRNA20713136
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNFAIP6 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNFAIP6 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of TNFAIP6 mRNA17562736
D000111AcetylcysteineAcetylcysteine inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]21220312
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Zearalenone results in decreased expression of TNFAIP6 mRNA]26386189
D020106AcrylamideAcrylamide results in decreased expression of TNFAIP6 mRNA28959563
C472668AEOL 10150AEOL 10150 results in decreased expression of TNFAIP6 mRNA12374626
D000447AldehydesAldehydes results in increased expression of TNFAIP6 mRNA25014914
D001149Arsenates[Atrazine co-treated with Arsenates] results in increased expression of TNFAIP6 mRNA18585445
D001151ArsenicArsenic results in decreased expression of TNFAIP6 mRNA16835338
C006632arsenic trioxidearsenic trioxide results in decreased expression of TNFAIP6 mRNA19128835
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of TNFAIP6 mRNA"24160326|2535159
D001241AspirinAspirin results in increased expression of TNFAIP6 mRNA15928584
D001280Atrazine[Atrazine co-treated with Arsenates] results in increased expression of TNFAIP6 mRNA18585445
D001280AtrazineAtrazine results in decreased expression of TNFAIP6 mRNA22378314
C547126AZM551248AZM551248 results in increased expression of TNFAIP6 mRNA22323515
D001554BenzeneBenzene affects the expression of TNFAIP6 mRNA21147609
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of TNFAIP6 mRNA22178795
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of TNFAIP6 mRNA20713471
C038682benzyl bromidebenzyl bromide results in increased expression of TNFAIP6 mRNA20713136
D004958Estradiol4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA]20660070
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA20660070
D004958EstradiolEstradiol results in decreased expression of TNFAIP6 mRNA25878060
D004958EstradiolN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA]20660070
D004958Estradiolpepstatin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA]20660070
C483161beta-hydroxy simvastatin acidbeta-hydroxy simvastatin acid results in decreased expression of TNFAIP6 mRNA18192240
C006780bisphenol Abisphenol A results in decreased expression of TNFAIP6 mRNA29027980
C006780bisphenol Abisphenol A results in increased expression of TNFAIP6 mRNA27685785
C006780bisphenol Abisphenol A results in decreased expression of TNFAIP6 mRNA25181051
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]21220312
C018475butyraldehydebutyraldehyde results in increased expression of TNFAIP6 mRNA26079696
D002118CalciumCalcium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]16768462
D002118CalciumCalcium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein]16768462
D002122Calcium ChlorideCalcium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]16768462
D002122Calcium ChlorideCalcium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein]16768462
D002809Chondroitin SulfatesTNFAIP6 protein promotes the reaction [ITIH1 protein binds to Chondroitin Sulfates]25561734
D002994ClofibrateClofibrate results in decreased expression of TNFAIP6 mRNA22300585
D003035Cobalt[tungsten carbide co-treated with Cobalt] results in decreased expression of TNFAIP6 mRNA18078969
C018021cobaltous chloridecobaltous chloride results in decreased expression of TNFAIP6 mRNA24386269
C026305cobalt sulfatecobalt sulfate results in increased expression of TNFAIP6 mRNA20713136
D005576ColforsinColforsin results in increased expression of TNFAIP6 mRNA24784705
D005576ColforsinJM 3100 inhibits the reaction [Colforsin results in increased expression of TNFAIP6 mRNA]24784705
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of TNFAIP6 mRNA20971185
C004742daidzein[Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of TNFAIP6 mRNA16963248
D003703DemecolcineDemecolcine results in increased expression of TNFAIP6 mRNA23649840
D003907DexamethasoneDexamethasone results in decreased expression of TNFAIP6 mRNA25047013
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of TNFAIP6 mRNA21266533
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of TNFAIP6 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of TNFAIP6 mRNA27392435
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in decreased expression of TNFAIP6 mRNA26924002
C024629dimethyl phthalatedimethyl phthalate affects the expression of TNFAIP6 mRNA26924002
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of TNFAIP6 mRNA17374397
D004147DioxinsDioxins affects the expression of TNFAIP6 mRNA20463971
D004237DiuronDiuron results in decreased expression of TNFAIP6 mRNA25152437
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of TNFAIP6 mRNA"23811387
D004391DustDust results in increased expression of TNFAIP6 mRNA17805423
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of TNFAIP6 mRNA15834898|1735126
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of TNFAIP6 mRNA23649840
D005054EugenolEugenol results in increased expression of TNFAIP6 mRNA17374397|2071313
D015025ZearalenoneAcetylcysteine inhibits the reaction [Zearalenone results in decreased expression of TNFAIP6 mRNA]26386189
D015025ZearalenoneZearalenone results in decreased expression of TNFAIP6 mRNA26386189
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in increased expression of TNFAIP6 mRNA28329830
D005557FormaldehydeFormaldehyde results in increased expression of TNFAIP6 mRNA23649840
D009240N-Formylmethionine Leucyl-PhenylalanineTNFAIP6 protein modified form results in decreased susceptibility to N-Formylmethionine Leucyl-Phenylalanine12401803
C039281furanfuran results in increased expression of TNFAIP6 mRNA27387713
D019833Genistein[Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of TNFAIP6 mRNA16963248
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]17109745
D005944GlucosamineGlucosamine results in decreased expression of TNFAIP6 mRNA17109745
D005944GlucosamineIL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA]17109745
D005947GlucoseGlucose results in increased expression of TNFAIP6 mRNA17178593
D005978GlutathioneGlutathione inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]21220312
C086566glycitein[Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of TNFAIP6 mRNA16963248
D006064Gonadotropins, Equine"[Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of TNFAIP6 mRNA"15831568
D006063Chorionic Gonadotropin"[Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of TNFAIP6 mRNA"15831568
D006820Hyaluronic AcidTNFAIP6 protein modified form binds to Hyaluronic Acid12401803
D006820Hyaluronic AcidTNFAIP6 protein promotes the reaction [ITIH1 protein binds to Hyaluronic Acid]25561734
D006820Hyaluronic AcidTNFAIP6 protein binds to and results in increased stability of Hyaluronic Acid15836955
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of TNFAIP6 mRNA21220312
D006861Hydrogen PeroxideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFAIP6 mRNA]21220312
D006861Hydrogen PeroxideU 0126 inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFAIP6 mRNA]21220312
C013038hydroxyhydroquinone4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of TNFAIP6 mRNA]24530881
C013038hydroxyhydroquinonehydroxyhydroquinone results in increased expression of TNFAIP6 mRNA24530881
C051890irinotecanirinotecan metabolite results in decreased expression of TNFAIP6 mRNA15956246
C051890irinotecanirinotecan results in decreased expression of TNFAIP6 mRNA15956246
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of TNFAIP6 mRNA27392435
C088327JM 3100JM 3100 inhibits the reaction [Colforsin results in increased expression of TNFAIP6 mRNA]24784705
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TNFAIP6 mRNA15860229|1819289
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TNFAIP6 mRNA16415329
D008070LipopolysaccharidesRanitidine promotes the reaction [Lipopolysaccharides results in increased expression of TNFAIP6 mRNA]16415329
D008274MagnesiumMagnesium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]16768462
D008274MagnesiumMagnesium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein]16768462
D015636Magnesium ChlorideMagnesium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]16768462
D015636Magnesium ChlorideMagnesium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein]16768462
D008345ManganeseManganese promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]16768462
D008345ManganeseManganese promotes the reaction [ITIH2 protein binds to TNFAIP6 protein]16768462
C025340manganese chloridemanganese chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]16768462
C025340manganese chloridemanganese chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein]16768462
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNFAIP6 mRNA"27188386
D008694MethamphetamineMethamphetamine results in decreased expression of TNFAIP6 mRNA26307267
C002950methylformamidemethylformamide affects the expression of TNFAIP6 mRNA17040096
C002950methylformamidemethylformamide analog affects the expression of TNFAIP6 mRNA17040096
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of TNFAIP6 mRNA23458150
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of TNFAIP6 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of TNFAIP6 mRNA23649840
C517284monomethyl phthalatemonomethyl phthalate affects the expression of TNFAIP6 mRNA26924002
C523799MRK 003MRK 003 results in decreased expression of TNFAIP6 mRNA21169257
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFAIP6 mRNA]21220312
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]21220312
C078131N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamideN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA]20660070
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of TNFAIP6 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of TNFAIP6 mRNA"25554681
C031721naphthalenenaphthalene results in increased expression of TNFAIP6 mRNA18978301
D009285NaphthoquinonesNaphthoquinones results in increased expression of TNFAIP6 mRNA23811387
D000068577NebivololNebivolol results in decreased expression of TNFAIP6 mRNA17467819
D009532NickelNickel results in increased expression of TNFAIP6 mRNA24768652|2558310
C022838nickel chloridenickel chloride results in increased expression of TNFAIP6 mRNA17312168
C029938nickel sulfatenickel sulfate results in increased expression of TNFAIP6 mRNA17374397|2071313
C570897NSC668394NSC668394 results in increased expression of TNFAIP6 mRNA27137931
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of TNFAIP6 mRNA20971185
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of TNFAIP6 mRNA25729387
D010121OxytocinOxytocin results in increased expression of TNFAIP6 protein23707249
D010126OzoneOzone results in increased expression of TNFAIP6 mRNA17460151
D010126OzoneOzone results in increased expression of TNFAIP6 mRNA28623178
D010269ParaquatTNFAIP6 protein inhibits the reaction [Paraquat results in increased expression of IL1B mRNA]24912639|2631368
D010269ParaquatTNFAIP6 protein inhibits the reaction [Paraquat results in increased expression of IL6 mRNA]24912639|2631368
D010269ParaquatTNFAIP6 protein inhibits the reaction [Paraquat results in increased expression of TNF mRNA]24912639|2631368
D052638Particulate MatterParticulate Matter results in increased expression of TNFAIP6 mRNA17987463
C046012pentanalpentanal results in increased expression of TNFAIP6 mRNA26079696
C031375pepstatinpepstatin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA]20660070
D010457PeptidoglycanPeptidoglycan results in increased expression of TNFAIP6 mRNA15860229
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of TNFAIP6 mRNA]19482888
D010634PhenobarbitalPhenobarbital results in decreased expression of TNFAIP6 mRNA19270015
D010634PhenobarbitalPhenobarbital results in increased expression of TNFAIP6 mRNA19482888
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNFAIP6 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of TNFAIP6 mRNA26272509
D010936Plant ExtractsPlant Extracts results in increased expression of TNFAIP6 mRNA21297082
D011374Progesterone4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA]20660070
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA20660070
D011374ProgesteroneN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA]20660070
D011374Progesteronepepstatin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of TNFAIP6 mRNA]20660070
D011374ProgesteroneProgesterone results in decreased expression of TNFAIP6 mRNA20660070
D011374ProgesteroneProgesterone results in increased expression of TNFAIP6 mRNA18070364
C005556propionaldehydepropionaldehyde results in increased expression of TNFAIP6 mRNA26079696
D011441PropylthiouracilPropylthiouracil results in increased expression of TNFAIP6 mRNA24780913
D011899RanitidineRanitidine promotes the reaction [Lipopolysaccharides results in increased expression of TNFAIP6 mRNA]16415329
C059514resveratrolresveratrol results in increased expression of TNFAIP6 mRNA25866375
C059514resveratrolresveratrol results in increased expression of TNFAIP6 mRNA25888808
C093642SB 203580SB 203580 results in decreased expression of TNFAIP6 mRNA20660070
D012643SeleniumSelenium results in increased expression of TNFAIP6 mRNA17293063
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of TNFAIP6 mRNA"24160326
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of TNFAIP6 mRNA25895662
D012822Silicon DioxideSilicon Dioxide results in increased expression of TNFAIP6 mRNA25351596
C017947sodium arsenitesodium arsenite results in decreased expression of TNFAIP6 mRNA12016162
D012967Sodium Dodecyl SulfateSodium Dodecyl Sulfate results in decreased expression of TNFAIP6 mRNA20713136
D012999SomanSoman results in increased expression of TNFAIP6 mRNA19281266
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TNFAIP6 mRNA21998131
D019284ThapsigarginThapsigargin results in decreased expression of TNFAIP6 mRNA22378314
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TNFAIP6 mRNA28111298
C024746tobacco tartobacco tar results in increased expression of TNFAIP6 mRNA19559774
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of TNFAIP6 mRNA25729387
D014212TretinoinTretinoin results in decreased expression of TNFAIP6 mRNA23724009
C057693troglitazonetroglitazone results in increased expression of TNFAIP6 mRNA19140230
C002802tungsten carbide[tungsten carbide co-treated with Cobalt] results in decreased expression of TNFAIP6 mRNA18078969
D014415TunicamycinTunicamycin results in decreased expression of TNFAIP6 mRNA22378314
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [LHB protein results in increased expression of TNFAIP6 mRNA]15459120
C113580U 0126U 0126 inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFAIP6 mRNA]21220312
C113580U 0126U 0126 inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]21220312
D014635Valproic AcidValproic Acid results in increased expression of TNFAIP6 mRNA24896083
D001335Vehicle EmissionsVehicle Emissions results in increased expression of TNFAIP6 mRNA17987463
D014750VincristineVincristine results in increased expression of TNFAIP6 mRNA23649840
D002762CholecalciferolCholecalciferol results in increased expression of TNFAIP6 mRNA17170073
C088658zoledronic acidzoledronic acid results in increased expression of TNFAIP6 mRNA20977926
D015054ZymosanTNFAIP6 protein modified form inhibits the reaction [Zymosan results in increased expression of CXCL1 protein]12401803
D015054ZymosanTNFAIP6 protein modified form inhibits the reaction [Zymosan results in increased expression of TNF protein]12401803
D015054ZymosanTNFAIP6 protein modified form results in decreased susceptibility to Zymosan12401803

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005041low-density lipoprotein particle receptor activity-IBA21873635  
GO:0005515protein binding-IPI18042364  18586671  22267482  24501198  27044744  
GO:0005540hyaluronic acid binding-IEA-  
GO:0030169low-density lipoprotein particle binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0006954inflammatory response-TAS1730767  
GO:0007155cell adhesion-IEA-  
GO:0007165signal transduction-TAS1730767  
GO:0007267cell-cell signaling-TAS1730767  
GO:0030335positive regulation of cell migration-IEA-  
GO:0030728ovulation-IEA-  
GO:0043312neutrophil degranulation-TAS-  
GO:0050728negative regulation of inflammatory response-IDA21569482  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IEA-  
GO:1904724tertiary granule lumen-TAS-  
GO:1904813ficolin-1-rich granule lumen-TAS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-6798695Neutrophil degranulationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
20862590Gene expression analysis in induced sputum from welders with and without airway-related symptoms. (2011 Jan)Jonsson LSInt Arch Occup Environ Health