Gene: TP53

7157
BCC7|LFS1|P53|TRP53
tumor protein p53
protein-coding
17p13.1
Ensembl:ENSG00000141510 MIM:191170 Vega:OTTHUMG00000162125 UniprotKB:P04637
NG_017013.2
PubMed
ND|AD
203   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.182e-1 (AD)  6.734e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CNN30.872
TNFRSF1A0.864
MSN0.851
TMBIM10.85
ASAP30.848
TEAD30.843
F30.841
SLC44A30.838
TRAF3IP20.834
SH3BP20.827

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ABCC12-0.553
CALHM1-0.55
SLC7A4-0.545
AGMAT-0.525
KCNB2-0.515
CNTN6-0.514
NEUROD6-0.514
PPEF1-0.51
PPL-0.504
CACNA1F-0.502

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00945Acetylsalicylic acidSmall Molecule50-78-2ApprovedTarget
DB01593ZincSmall Molecule7440-66-6Approved|InvestigationalTarget
DB03347Triethyl PhosphateSmall MoleculeExperimentalTarget
DB05404AZD 3355Small Molecule-InvestigationalTarget
DB083631-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamineSmall MoleculeExperimentalTarget
ID Drug Name Action PubMed
C06779510-decarbamoylmitomycin C10-decarbamoylmitomycin C results in increased stability of TP53 protein20536192
C06779510-decarbamoylmitomycin C[10-decarbamoylmitomycin C results in increased stability of TP53 protein] which results in increased expression of CDKN1A mRNA20536192
C49019111,11'-dideoxyverticilin"11,11'-dideoxyverticilin results in increased expression of and results in increased phosphorylation of TP53 protein"15963507
C0264861,2,5,6-dibenzanthracene"TP53 protein affects the reaction [1,2,5,6-dibenzanthracene results in increased expression of CYP1A1 protein]"25398514
C0264861,2,5,6-dibenzanthracene"TP53 protein results in increased susceptibility to 1,2,5,6-dibenzanthracene"25398514
C5172321,2-dibromo-4-(1,2-dibromoethyl)cyclohexane"1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane results in increased expression of TP53 mRNA"23958786
C5172321,2-dibromo-4-(1,2-dibromoethyl)cyclohexane"1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane affects the expression of TP53 mRNA"24375616
C0449851',2'-dihydrorotenone"1',2'-dihydrorotenone results in decreased phosphorylation of and results in decreased expression of TP53 protein"24615755
C0320411,2-diphenylhydrazine"[Copper co-treated with 1,2-diphenylhydrazine] results in increased mutagenesis of TP53 gene"10798712
C0320411,2-diphenylhydrazine"piperidine promotes the reaction [[Copper co-treated with 1,2-diphenylhydrazine] results in increased mutagenesis of TP53 gene]"10798712
C5191841,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)"[1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000) co-treated with Quercetin] results in increased expression of TP53 protein"23529952
C5768821-(2-trifluoromethoxyphenyl)-2-nitroethanone1-(2-trifluoromethoxyphenyl)-2-nitroethanone affects the activity of TP53 protein25596134
C0389831,3-dimethylthiourea"1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]"17035936
C4296851,4,5,8-naphthalenetetracarboxylic diimide"1,4,5,8-naphthalenetetracarboxylic diimide analog results in increased expression of TP53 protein"19954251
C4792341-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-2,7,9a-benzo(cd)azulen-6-one"1-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-2,7,9a-benzo(cd)azulen-6-one inhibits the reaction [resveratrol results in increased acetylation of TP53 protein]"25533949
C0741531,4-phenylenebis(methylene)selenocyanate"1,4-phenylenebis(methylene)selenocyanate results in increased expression of TP53 mRNA"17205524
C0741531,4-phenylenebis(methylene)selenocyanate"AR protein promotes the reaction [1,4-phenylenebis(methylene)selenocyanate results in increased expression of TP53 mRNA]"17205524
C5602961,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one"1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one results in increased phosphorylation of TP53 protein"21504179
C07258116-hydroxycleroda-3,13(14)-dien-15,16-olide"16-hydroxycleroda-3,13(14)-dien-15,16-olide results in increased expression of TP53 protein"23628706
C00202917alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol"17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in increased expression of TP53 protein"16019103
C44865917-(dimethylaminoethylamino)-17-demethoxygeldanamycinTP53 gene affects the susceptibility to 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin17085670
C4069821,8-diazafluoren-one"[1,8-diazafluoren-one results in decreased activity of HMOX1 protein] inhibits the reaction [cobaltiprotoporphyrin results in increased expression of TP53 protein]"18042465
C495172(19Z)-halichondramide(19Z)-halichondramide results in increased expression of TP53 protein23147639
C0479481'-acetoxychavicol acetate[1'-acetoxychavicol acetate co-treated with Butyric Acid] results in increased phosphorylation of TP53 protein24480522
C0364231-aminomethylphosphonic acid1-aminomethylphosphonic acid results in increased expression of TP53 protein23983455
C0952841H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one"1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one results in increased stability of and results in increased expression of and results in increased phosphorylation of TP53 protein"16288207
C1053511-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene"[1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in decreased degradation of HIF1A protein] which results in increased phosphorylation of and results in increased activity of TP53 protein"18424783
C1087311'-(hydroxymethyl)eugenol1'-(hydroxymethyl)eugenol results in increased phosphorylation of TP53 protein28818686
C0512461-methylanthracene1-methylanthracene results in increased phosphorylation of TP53 protein17941746
C0415071-methylphenanthrene1-methylphenanthrene results in increased phosphorylation of TP53 protein17941746
C0326681-nitropyrene1-nitropyrene results in increased expression of TP53 protein10837373|2204453
C0326681-nitropyrene1-nitropyrene results in increased expression of TP53 protein modified form22044530
C0326681-nitropyrene2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased susceptibility to [Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]22044530
C0326681-nitropyrene[beta-Naphthoflavone binds to and results in increased activity of AHR protein] results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]22044530
C0326681-nitropyreneCYP1A1 protein affects the susceptibility to [Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]22044530
C0326681-nitropyrenenutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]22044530
C0326681-nitropyrenenutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein modified form]22044530
C0326681-nitropyreneTetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]22044530
C0326681-nitropyreneTetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein modified form]22044530
C0326681-nitropyreneTetrachlorodibenzodioxin results in decreased susceptibility to [nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]22044530
C0326681-nitropyreneTetrachlorodibenzodioxin results in decreased susceptibility to [nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein modified form]]22044530
C0326681-nitropyreneTP53 affects the reaction [1-nitropyrene results in increased expression of BAX mRNA]10837373
C0326681-nitropyreneTP53 affects the reaction [1-nitropyrene results in increased expression of MDM2 mRNA]10837373
C0326681-nitropyreneTP53 affects the susceptibility to 1-nitropyrene10837373
C0326681-nitropyrene1-nitropyrene affects the expression of TP53 mRNA11201684
C0326681-nitropyrene1-nitropyrene results in increased activity of TP53 protein22044530
C0326681-nitropyrenepifithrin results in decreased susceptibility to [1-nitropyrene results in increased activity of TP53 protein]22044530
C0326681-nitropyreneTetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased activity of TP53 protein]22044530
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased expression of TP53 protein"22101421
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[U 0126 co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in increased expression of TP53 protein"22101421
C0948592,2',3,3',4,6'-hexachlorobiphenyl"2,2',3,3',4,6'-hexachlorobiphenyl results in decreased expression of TP53 mRNA"17445852
C0948592,2',3,3',4,6'-hexachlorobiphenyl"2,2',3,3',4,6'-hexachlorobiphenyl results in increased expression of TP53 mRNA"17445852
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of TP53 mRNA"27291303
C5461932-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide"2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein modified form]"25977998
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol affects the localization of TP53 protein]18446786
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol promotes the reaction [PTGS2 protein binds to TP53 protein modified form]]16928824
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased expression of TP53 mRNA]11889192
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of TP53 protein]12131363|1844678
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]11889192|1681411
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased expression of TP53 protein15880691
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-oneTP53 protein promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased abundance of Reactive Oxygen Species]15880691
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-oneTP53 protein results in increased susceptibility to 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one15880691
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Doxorubicin results in increased phosphorylation of TP53 protein]18775851
C0061832-(2-aminoethyl)pyridine[Copper binds to Isatin binds to 2-(2-aminoethyl)pyridine] which results in increased expression of TP53 protein17327230
C4512192,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one inhibits the reaction [TP53 protein mutant form binds to TP73 protein]"21647879
C4512192,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one promotes the reaction [Cisplatin results in increased localization of TP53 protein mutant form]"21109480
C4512192,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one promotes the reaction [TP53 protein results in increased susceptibility to resveratrol]"23152798
C4512192,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one results in increased activity of TP53 protein"15860260
C4512192,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one results in increased expression of and results in increased localization of and results in increased activity of TP53 protein mutant form"21109480
C4512192,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"TP53 protein affects the reaction [2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one results in increased expression of BAX mRNA]"21109480
C4512192,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"TP53 protein affects the reaction [2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one results in increased expression of CDKN1A mRNA]"21109480
C4512192,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"TP53 protein mutant form results in increased activity of 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"21647879
C4512192,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one results in increased activity of TP53 protein"23152798
C0445652-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide results in increased expression of TP5316142332
C0445652-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide results in increased expression of TP53 protein15529313|1575432
C0445652-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide results in increased expression of TP53 protein modified form16857806
C0445652-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide results in increased phosphorylation of TP53 protein15529313|1575432
C0445652-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamideTP53 protein results in increased susceptibility to 2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide analog16142332
C5877342,3,5-trichloro-6-phenyl-(1,4)benzoquinone"2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TP53 protein"26451628
C5877342,3,5-trichloro-6-phenyl-(1,4)benzoquinone"2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TP53 protein modified form"26451628
C5877342,3,5-trichloro-6-phenyl-(1,4)benzoquinone"Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TP53 protein]"26451628
C5877342,3,5-trichloro-6-phenyl-(1,4)benzoquinone"Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TP53 protein modified form]"26451628
C5877342,3,5-trichloro-6-phenyl-(1,4)benzoquinone"TP53 protein promotes the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in decreased expression of CDK2 protein]"26451628
C5877342,3,5-trichloro-6-phenyl-(1,4)benzoquinone"TP53 protein promotes the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased cleavage of CASP3 protein]"26451628
C5877342,3,5-trichloro-6-phenyl-(1,4)benzoquinone"TP53 protein promotes the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of CDKN1A protein]"26451628
C5877342,3,5-trichloro-6-phenyl-(1,4)benzoquinone"TP53 protein promotes the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of FAS protein]"26451628
C4166532-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone results in increased expression of and results in increased phosphorylation of TP53 protein23523585
C4166532-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone results in increased expression of TP53 mRNA23523585
C4166532-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinoneCaffeine inhibits the reaction [2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone results in increased phosphorylation of TP53 protein]23523585
C4166532-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinoneTP53 protein results in increased susceptibility to 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone23523585
C0817662,4,4'-trichlorobiphenyl"2,4,4'-trichlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]"19751709
C0817662,4,4'-trichlorobiphenyl"2,4,4'-trichlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein]"20840854
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene affects the localization of and results in increased expression of TP53 protein]"24954032
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein]"20840854
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein]"24954032
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased activity of TP53 protein"27589886
C0140242,4,5,2',4',5'-hexachlorobiphenyl"Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]"24954032
C0140242,4,5,2',4',5'-hexachlorobiphenyl"Okadaic Acid promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]"24954032
C0098282,4,5,2',5'-pentachlorobiphenyl"2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]"19751709
C0098282,4,5,2',5'-pentachlorobiphenyl"2,4,5,2',5'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]"20840854
C0098282,4,5,2',5'-pentachlorobiphenyl"2,4,5,2',5'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein]"20840854
C0098282,4,5,2',5'-pentachlorobiphenyl"2,4,5,2',5'-pentachlorobiphenyl results in decreased expression of TP53 protein"19751709
C5290612-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone"2-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone inhibits the reaction [TP53 protein mutant form binds to TP73 protein]"18424558
C5290612-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone"TP53 protein mutant form affects the reaction [2-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone results in increased expression of BBC3 mRNA]"18424558
C5290612-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone"TP53 protein mutant form affects the reaction [2-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone results in increased expression of CDKN1A mRNA]"18424558
C5290612-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone"TP53 protein mutant form affects the reaction [2-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone results in increased expression of TP73 mRNA]"18424558
C0245642,4,6-trichlorophenol"2,4,6-trichlorophenol results in increased mutagenesis of TP53 gene"18939895
C0573492,4-decadienal"2,4-decadienal results in decreased expression of TP53 mRNA"12921975
C5431502-(4-((dimethylamino)methyl)benzylidene)-5,6-dimethoxy-2,3-dihydroinden-1-one"2-(4-((dimethylamino)methyl)benzylidene)-5,6-dimethoxy-2,3-dihydroinden-1-one inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]"19345205
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of TP53 mRNA"21346803
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]]15763944
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]20856197
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nitric Oxide results in increased phosphorylation of TP53 protein]16024610
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in decreased expression of TP53 protein]26942697
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]17534123
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spermine nitric oxide complex results in increased phosphorylation of TP53 protein]16024610
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of TP53 protein15001399
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of TP53 protein25305377
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneTP53 protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]20856197
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneTP53 protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of CASP8 protein]]20856197
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneTP53 protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of CASP9 protein]]20856197
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneTP53 protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased expression of and results in increased activity of BAX protein]]20856197
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneTP53 protein promotes the reaction [[Doxorubicin co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in increased expression of BBC3 protein]20856197
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneTP53 protein results in increased susceptibility to [Doxorubicin co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one]20856197
C1177762,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone"2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of and results in increased cleavage of TP53 protein"26630137
C1177762,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone"2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein modified form"26630137
C1177762,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone"2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein]"26630137
C1177762,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone"2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein modified form]"26630137
C1177762,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone"Dicumarol inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein]"26630137
C1177762,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone"Dicumarol inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein modified form]"26630137
C1177762,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone"pyrazolanthrone inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein]"26630137
C1177762,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone"pyrazolanthrone inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein modified form]"26630137
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of TP53 mRNA"21346803
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of TP53 protein"11425520|1563514
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of TP53 protein"23810796
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased mutagenesis of TP53 gene"8844820
C5464602-amino-3-methyl-3H-imidazo(4,5-f)quinoline"2-amino-3-methyl-3H-imidazo(4,5-f)quinoline results in increased expression of TP53 mRNA"23810796
C5464602-amino-3-methyl-3H-imidazo(4,5-f)quinoline"2-amino-3-methyl-3H-imidazo(4,5-f)quinoline results in increased expression of TP53 protein"23810796
C0352082-amino-4,6-dinitrotoluene"2-amino-4,6-dinitrotoluene results in increased activity of TP53 protein"14577614
C0352082-amino-4,6-dinitrotoluene"2-amino-4,6-dinitrotoluene results in increased expression of TP53 protein"14577614
C0121772-aminofluorene2-aminofluorene results in increased expression of TP53 protein9163691
C0127962-butenal2-butenal results in increased expression of TP53 protein23535401
C4370432-butylamino-2-demethoxy-hypocrellin B2-butylamino-2-demethoxy-hypocrellin B results in increased expression of TP53 mRNA17045927
C4370432-butylamino-2-demethoxy-hypocrellin B"2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide inhibits the reaction [2-butylamino-2-demethoxy-hypocrellin B results in increased expression of TP53 mRNA]"17045927
C4370432-butylamino-2-demethoxy-hypocrellin BSodium Azide inhibits the reaction [2-butylamino-2-demethoxy-hypocrellin B results in increased expression of TP53 mRNA]17045927
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased expression of TP53 protein19111594
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased phosphorylation of TP53 protein19111594
C0312782-chloroethyl ethyl sulfide2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of TP53 protein]19111594
C0312782-chloroethyl ethyl sulfideATM protein affects the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of TP53 protein]19111594
C0312782-chloroethyl ethyl sulfideATR protein affects the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of TP53 protein]19111594
C0312782-chloroethyl ethyl sulfidewortmannin inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of TP53 protein]19111594
C0702792'-cyano-2'-deoxyarabinofuranosylcytosine2'-cyano-2'-deoxyarabinofuranosylcytosine results in increased phosphorylation of TP53 protein16061671
C1202752-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of and affects the localization of and results in increased activity of TP53 protein12869419
C1202752-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of and affects the localization of TP53 protein12807743
C0313192-hydroxyethyl disulfideTP53 protein affects the susceptibility to 2-hydroxyethyl disulfide22926048
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased susceptibility to [Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]22044530
C1098342-methylphenanthrene2-methylphenanthrene results in increased phosphorylation of TP53 protein17941746
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one"2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein]"26630137
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one"2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein modified form]"26630137
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of TP53 protein]19111594
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]]24933654
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of TP53 protein]24933654
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]22226932
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased expression of TP53 protein]19502594
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Clioquinol results in increased phosphorylation of TP53 protein]22627294
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Hydrogen Peroxide promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]]24933654
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Mustard Gas results in increased expression of TP53 protein]22119920
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Mustard Gas results in increased phosphorylation of TP53 protein]22119920
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein modified form]25977998
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]]24933654
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of TP53 protein]]24933654
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased phosphorylation of TP53 protein22119920
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [arsenic trioxide results in increased phosphorylation of TP53 protein]23337567
C0793912-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide"2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide inhibits the reaction [2-butylamino-2-demethoxy-hypocrellin B results in increased expression of TP53 mRNA]"17045927
C0043692-phenylphenol[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene10334203
C0043692-phenylphenolbathocuproine inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
C0043692-phenylphenolCAT protein inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
C0415253,3',4,5'-tetrahydroxystilbene"3,3',4,5'-tetrahydroxystilbene results in increased expression of TP53 protein"26341291
C0415253,3',4,5'-tetrahydroxystilbene"3,3',4,5'-tetrahydroxystilbene results in increased expression of TP53 protein modified form"26341291
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein"22290291
C0163923,3'-diindolylmethane"[3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3"22290291
C0163923,3'-diindolylmethane"[3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of PMAIP1"22290291
C0163923,3'-diindolylmethane"wortmannin inhibits the reaction [3,3'-diindolylmethane results in increased phosphorylation of TP53 protein]"22290291
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene affects the localization of TP53 protein]"20840854
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein]"20840854
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]"19751709
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [leptomycin B results in increased expression of TP53 protein]"19751709
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TP53 mRNA"21703328
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TP53 protein"19751709
C4228633,4,5,4'-tetrahydroxystilbene"3,4,5,4'-tetrahydroxystilbene results in increased activity of TP53 protein"11181455
C4228633,4,5,4'-tetrahydroxystilbene"[3,4,5,4'-tetrahydroxystilbene results in increased activity of TP53 protein] which results in increased expression of BAX mRNA"11181455
C4228633,4,5,4'-tetrahydroxystilbene"3,4,5,4'-tetrahydroxystilbene results in increased expression of TP53 mRNA"11181455
C4228633,4,5,4'-tetrahydroxystilbene"3,4,5,4'-tetrahydroxystilbene results in increased expression of TP53 protein"11181455
C4824923,4,5,4'-tetramethoxystilbene"3,4,5,4'-tetramethoxystilbene affects the expression of TP53 protein"15668717
C4824923,4,5,4'-tetramethoxystilbene"3,4,5,4'-tetramethoxystilbene results in increased expression of TP53 mRNA"22687606
C0612133',4',7-trihydroxyisoflavone"3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of TP53 mRNA]"22914566
C0612133',4',7-trihydroxyisoflavone"3',4',7-trihydroxyisoflavone results in increased expression of TP53 mRNA"22914566
C0612133',4',7-trihydroxyisoflavone"Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of TP53 mRNA]"22914566
C0454213,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine"3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine results in decreased expression of TP53 mRNA"23810796
C0454213,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine"3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine results in increased expression of TP53 protein"23810796
C5016343-(4-chlorophenyl)-3-(4-hydroxy-3,5-dimethoxybenzyloxy)-2-propyl-2,3-dihydroisoindol-1-one"3-(4-chlorophenyl)-3-(4-hydroxy-3,5-dimethoxybenzyloxy)-2-propyl-2,3-dihydroisoindol-1-one results in decreased activity of [MDM2 protein binds to TP53 protein]"21314128
C4781003,4-di-O-caffeoylquinic acid"3,4-di-O-caffeoylquinic acid results in decreased expression of TP53 protein"21872580
C4727913-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid analog results in increased phosphorylation of TP53 protein17512204
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [sodium arsenite results in decreased phosphorylation of TP53 protein]22706169
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]20199942
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [sodium arsenite affects the localization of TP53 protein]20375080
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [sodium arsenite results in increased phosphorylation of TP53 protein]20375080
C4340033-(4-methylphenylsulfonyl)-2-propenenitrileHSPA9 protein promotes the reaction [3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]]20199942
C5534723-(4-methylpiperazin)-8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carbonitrile"3-(4-methylpiperazin)-8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carbonitrile results in increased phosphorylation of and results in increased expression of and results in increased activity of TP53 protein"19182866
C4949143,5,3',4',5'-pentamethoxystilbene"3,5,3',4',5'-pentamethoxystilbene results in increased expression of TP53 protein"19916542
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole promotes the reaction [Camptothecin results in increased expression of TP53 protein]19481069
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in increased expression of TP53 protein19481069
C0345343,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid"3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid promotes the reaction [(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride results in increased expression of TP53 protein]"15475462
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Capsaicin results in increased expression of TP53 protein]22226932
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]22226932
C4790673-aminothioacridone3-aminothioacridone results in increased phosphorylation of and results in increased expression of TP53 protein15724842
C0541213-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone results in increased mutagenesis of TP53 gene11152562
C0917683'-methoxy-4'-nitroflavone3'-methoxy-4'-nitroflavone inhibits the reaction [Dioxins results in decreased expression of TP53 mRNA]15111621
C0917683'-methoxy-4'-nitroflavone3'-methoxy-4'-nitroflavone inhibits the reaction [Dioxins results in decreased expression of TP53 protein]15111621
C0917683'-methoxy-4'-nitroflavone3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TP53 mRNA]17070097
C0917683'-methoxy-4'-nitroflavone3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TP53 protein]17070097
C0917683'-methoxy-4'-nitroflavone3'-methoxy-4'-nitroflavone inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of TP53 mRNA]17070097
C0917683'-methoxy-4'-nitroflavone3'-methoxy-4'-nitroflavone inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of TP53 protein]17070097
C0259463-methyladenine[3-methyladenine co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein23380477
C0259463-methyladenine3-methyladenine inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein]23380477
C0259463-methyladenine3-methyladenine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
C1172203-nitrobenzanthrone3-nitrobenzanthrone results in increased mutagenesis of TP53 gene18765419
C0006147253'-oxomethylisoeugenol3'-oxomethylisoeugenol results in increased phosphorylation of TP53 protein28818686
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole"4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TP53 protein]"18085531
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]20067818
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in decreased phosphorylation of TP53 protein25305377
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]20067818
C5809354-((4-hydroxyphenylimino)methyl)benzene-1,2-diol"4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol results in increased expression of TP53 protein"25242450
C1191304-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TP53 protein]18805435
C1191304-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [Nicotine results in decreased expression of TP53 protein]18805435
C0352074-amino-2,6-dinitrotoluene"4-amino-2,6-dinitrotoluene affects the expression of TP53 mRNA"21346803
C4943564-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione results in increased phosphorylation of TP53 protein"24824809
C0067574-biphenylamine4-biphenylamine binds to TP53 gene12376482
C0067574-biphenylamineTP53 protein affects the susceptibility to 4-biphenylamine11804609
C0046584-chloroaniline4-chloroaniline affects the expression of TP53 mRNA27825931
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of TP53 mRNA15607904
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of TP53 protein15607904
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased mutagenesis of TP53 gene11050162
C0652504-hydroxy-equilenin4-hydroxy-equilenin results in decreased expression of TP53 mRNA15135645
C0248364-nitrophenolTP53 protein affects the glucuronidation of 4-nitrophenol11695553
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TP53 protein]18805435
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone affects the localization of TP53 protein19931552|2042134
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone inhibits the reaction [sodium arsenite affects the localization of TP53 protein]19931552
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone inhibits the reaction [sodium arsenite results in increased activity of TP53 protein]19931552
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TP53 protein18805435
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased ADP-ribosylation of TP53 protein20421341
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TP53 protein19931552|2177627
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of TP53 protein20421341
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TP53 protein]16401635
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of TP53 protein]16401635
C0415944-nonylphenol4-nonylphenol results in increased expression of TP53 mRNA27087316|2710977
C0415944-nonylphenol4-nonylphenol results in increased expression of TP53 protein27087316|2710977
C0415944-nonylphenol4-nonylphenol results in increased expression of TP53 mRNA20060579
C0804174-octylphenol4-octylphenol results in increased expression of TP53 mRNA20060579
C4948984-oxofenretinide4-oxofenretinide results in increased expression of TP53 protein16540676
C1052604-tert-octylphenol4-tert-octylphenol affects the expression of TP53 mRNA17950039
C1052604-tert-octylphenol4-tert-octylphenol results in increased expression of TP53 mRNA17011747
C5732335,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4H-1-benzopyran-4-one"5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4H-1-benzopyran-4-one results in increased expression of TP53 protein"26405812
C0806695,7-dihydroxy-6-methoxy-2-phenylchromen-4-one"5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in increased expression of TP53 protein modified form"23470866
C0806695,7-dihydroxy-6-methoxy-2-phenylchromen-4-one"diacetyldiphenylurea bisguanylhydrazone inhibits the reaction [5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in increased expression of TP53 protein modified form]"23470866
C0602985,7-dimethoxyflavone"[5,7-dimethoxyflavone co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA"21554863
C0602985,7-dimethoxyflavone"[5,7-dimethoxyflavone co-treated with Diethylnitrosamine] results in increased expression of TP53 protein"21554863
C439285(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride"3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid promotes the reaction [(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride results in increased expression of TP53 protein]"15475462
C439285(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride(5-fluoro-2-methyl-1-(4-pyridyl)methylene-3-(N-benzyl)-indene)-acetamide hydrochloride results in increased expression of TP53 protein15475462
C0587225-hydroxy-6,8,11,14,17-eicosapentaenoic acid"5-hydroxy-6,8,11,14,17-eicosapentaenoic acid affects the expression of TP53 mRNA"26984781
C4718436-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine results in increased expression of TP53 protein15958644
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine affects the localization of TP53 protein"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Curcumin results in increased phosphorylation of TP53 protein]"19020741
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased phosphorylation of and results in increased expression of TP53 protein"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"Acetylcysteine inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased expression of and results in increased phosphorylation of TP53 protein]"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"Caffeine inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased expression of and results in increased phosphorylation of TP53 protein]"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"TP53 mutant form inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in decreased expression of CCNB1 protein]"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"TP53 mutant form inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in decreased phosphorylation of and results in decreased expression of CDK1 protein]"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"TP53 mutant form inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased cleavage of CASP3 protein]"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"TP53 mutant form inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased cleavage of PARP1 protein]"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"TP53 mutant form inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased expression of CDKN1A protein]"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"TP53 protein results in increased susceptibility to (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"23274516
C57309764Cu-CB-TE2A-Y3-TATETP53 protein affects the localization of 64Cu-CB-TE2A-Y3-TATE22056254
C57309664Cu-DOTA-Y3-TATETP53 protein affects the localization of 64Cu-DOTA-Y3-TATE22056254
C4853836,7-dihydroxyflavone"6,7-dihydroxyflavone results in increased degradation of TP53 protein"14634213
C0005950156,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine"6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine results in decreased methylation of TP53 protein"28073004
C0005950156,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine"6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine results in increased expression of and results in decreased methylation of TP53 protein"28073004
C0005950156,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine"TP53 protein results in increased susceptibility to 6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine"28073004
C5605976,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide"6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide inhibits the reaction [HSPA9 protein binds to TP53 protein]"22155302
C5605976,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide"[6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide inhibits the reaction [HSPA9 protein binds to TP53 protein]] which affects the localization of and results in increased activity of TP53 protein"22155302
C5605976,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide"6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide inhibits the reaction [methoxyacetic acid results in increased expression of TP53 protein]"21573189
C5605976,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide"6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide results in increased expression of TP53 mRNA"22973447
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased acetylation of TP53 protein"24726431
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"Camptothecin inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased acetylation of TP53 protein]"24726431
C1143697,8-diacetoxy-4-methylcoumarin"7,8-diacetoxy-4-methylcoumarin results in increased expression of TP53 protein"19061872
C5403617,8-diacetoxy-4-methylthiocoumarin"7,8-diacetoxy-4-methylthiocoumarin results in increased expression of TP53 protein"19061872
C5538177-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one"7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one results in increased expression of TP53 mRNA"19936915
C5538177-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one"7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one results in increased expression of TP53 protein"19936915
C5591457-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine"7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine results in increased expression of TP53 protein"21417417
C4118687-diethylamino-4-methyl coumarin7-diethylamino-4-methyl coumarin results in increased expression of TP53 mRNA21538407
C0548527-hydroxystaurosporine7-hydroxystaurosporine results in decreased expression of TP53 protein11378265
C0030017-ketocholesterol7-ketocholesterol results in increased expression of TP53 protein25845326
C0030017-ketocholesterolAcetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of TP53 protein]25845326
C0030017-ketocholesterolBAY 11-7085 inhibits the reaction [7-ketocholesterol results in increased expression of TP53 protein]25845326
C0030017-ketocholesterolquercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [7-ketocholesterol results in increased expression of TP53 protein]25845326
C5228037-monohydroxyethylrutoside7-monohydroxyethylrutoside inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]17285121
C5228037-monohydroxyethylrutoside7-monohydroxyethylrutoside inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]17285121
C0801227-nitroindazole[7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat results in increased phosphorylation of TP53 protein]20478973
C0150088-azapurine8-azapurine analog results in increased expression of TP53 protein15993080
C0162768-bromocyclic GMP8-bromocyclic GMP results in increased expression of TP53 protein9888876
C0053999,10-phenanthrenequinone"9,10-phenanthrenequinone affects the localization of TP53 protein"29108775
C0469389,11-linoleic acid"9,11-linoleic acid results in increased phosphorylation of and affects the localization of TP53 protein"15992797
C0257249-methoxycamptothecin9-methoxycamptothecin results in increased expression of TP53 mRNA23369935
C0257249-methoxycamptothecin9-methoxycamptothecin results in increased expression of TP53 protein23369935
C072876A 771726A 771726 results in increased expression of TP53 mRNA10076546
C072876A 771726A 771726 results in increased expression of TP53 protein10076546
C542662AC 93253AC 93253 affects the expression of TP53 mRNA25912555
D000082AcetaminophenAcetaminophen results in increased expression of TP53 mRNA26946349
D000082AcetaminophenAcetaminophen results in decreased expression of TP53 mRNA21420995|2570463
D000082AcetaminophenAcetaminophen affects the expression of TP53 mRNA16701773
D000082AcetaminophenAcetaminophen promotes the reaction [MDM2 protein binds to TP53 protein]16330492
D000082AcetaminophenAcetaminophen results in decreased expression of TP53 protein16330492
D000082AcetaminophenAcetaminophen results in increased activity of TP53 protein25858767
D000082AcetaminophenAcetaminophen results in increased expression of TP53 mRNA21807079
D000082AcetaminophenAcetaminophen results in increased phosphorylation of TP53 protein16330492
D000082Acetaminophenbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]16330492
D000082AcetaminophenChlormethiazole inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]16330492
D000082AcetaminophenEtoposide promotes the reaction [Acetaminophen results in increased phosphorylation of TP53 protein]16330492
D000082AcetaminophenFluorouracil promotes the reaction [Acetaminophen results in increased phosphorylation of TP53 protein]16330492
D000082Acetaminophenlactacystin inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]16330492
D000082AcetaminophenAcetaminophen results in decreased expression of TP53 protein16330492
C464485acetamipridacetamiprid results in increased expression of TP53 mRNA29091792
C464485acetamiprid[iprodione co-treated with acetamiprid] results in decreased expression of TP53 mRNA29091792
C464485acetamiprid[iprodione co-treated with pyrimethanil co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C464485acetamiprid[iprodione co-treated with pyrimethanil co-treated with pyrachlostrobin co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C464485acetamiprid[pyrimethanil co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C464485acetamiprid[pyrimethanil co-treated with pyrachlostrobin co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C056165acetovanilloneacetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]22431579
D000099Acetoxyacetylaminofluorene[Acetoxyacetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TP53 protein10741303
C487680acetylbritannilatoneacetylbritannilatone analog results in increased expression of TP53 protein27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased activity of CASP3 protein]27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased activity of CASP8 protein]27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased activity of CASP9 protein]27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased cleavage of PARP1 protein]27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased expression of BAX mRNA]27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased expression of BBC3 mRNA]27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased expression of CDKN1A mRNA]27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased expression of FAS mRNA]27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased expression of PMAIP1 mRNA]27262408
D000111Acetylcysteine"[Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]"18951928
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TP53 protein]"26451628
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TP53 protein modified form]"26451628
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased expression of and results in increased phosphorylation of TP53 protein]"23274516
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Aristolochic Acids results in increased phosphorylation of TP53 protein]24792323
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of TP53 protein]15904916
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenite results in increased expression of TP53 protein]22260869
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
D000111AcetylcysteineAcetylcysteine inhibits the reaction [ATM protein promotes the reaction [Doxorubicin results in increased activity of TP53 protein]]15489221
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Camptothecin results in increased expression of TP53 protein modified form]17555331
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]14871840
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein]27634759
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cisplatin results in increased expression of TP53]15496615
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cisplatin results in increased glutathionylation of TP53 protein]17555331
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of and results in increased activity of TP53 protein]10951577
D000111AcetylcysteineAcetylcysteine inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]19202565
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]]15489221
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein]25939952
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]9535218
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]9535218
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Methotrexate results in increased expression of TP53 mRNA]22183962
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Methotrexate results in increased expression of TP53 protein]24967384
D000111AcetylcysteineAcetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of TP53 mRNA]9535218
D000111AcetylcysteineAcetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of TP53 protein]9535218
D000111AcetylcysteineAcetylcysteine inhibits the reaction [oxaliplatin results in increased expression of TP53 protein]19728331
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]10951577
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of TP53 protein]26942697
D000111AcetylcysteineAcetylcysteine inhibits the reaction [perfosfamide results in increased expression of TP53]18034189
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Phytochemicals results in increased phosphorylation of TP53 protein]25305377
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Reactive Oxygen Species affects the localization of TP53 protein]26884717
D000111AcetylcysteineAcetylcysteine inhibits the reaction [TNF protein results in increased expression of TP53 mRNA]9535218
D000111AcetylcysteineAcetylcysteine inhibits the reaction [TNF protein results in increased expression of TP53 protein]9535218
D000111AcetylcysteineAcetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of TP53 protein]23711929
D000111AcetylcysteineAcetylcysteine inhibits the reaction [TP53 protein results in increased abundance of Reactive Oxygen Species]15059885
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]18951928
D000111AcetylcysteineAcetylcysteine results in decreased activity of TP53 protein15059885
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Nitroprusside results in increased expression of TP53]19725096
D000111AcetylcysteineAcetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of TP53 protein]25845326
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression of TP53 protein]]28181396
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Aflatoxin B1 results in increased expression of TP53 protein]28181396
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of TP53 protein]27658547
D000111AcetylcysteineAcetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Aflatoxin B1 results in increased expression of TP53 protein]]28181396
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of TP53 protein]18563748
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Quercetin analog results in decreased phosphorylation of TP53 protein]23907460
D000111AcetylcysteineAcetylcysteine results in decreased expression of TP53 protein23183129
D000111AcetylcysteineAcetylcysteine results in increased phosphorylation of TP53 protein23907460
D000111AcetylcysteineAcetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]]29109043
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA]]29109043
D000111AcetylcysteineAcetylcysteine promotes the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]29109043
D000157AconitineAconitine results in increased expression of TP53 protein24840785
D000165Acridine OrangeAcridine Orange results in increased stability of and results in increased activity of TP53 protein16177561
D000171AcroleinAcrolein results in increased phosphorylation of TP53 protein17196791
D000171AcroleinAcrolein affects the metabolism of TP53 protein12807757
D000171AcroleinAcrolein binds to TP53 gene17030796
D000171AcroleinAcrolein inhibits the reaction [Benzo(a)pyrene results in increased activity of TP53 protein]12807757
D000171AcroleinAcrolein results in decreased activity of TP53 protein12807757|1675383
D000171AcroleinAcrolein results in increased mutagenesis of TP53 gene17030796
D000171Acrolein[ferric oxide analog co-treated with Acrolein] results in increased expression of TP53 protein24847785
D020106AcrylamideAcrylamide results in increased expression of TP53 protein modified form20734998
D020106AcrylamideAcrylamide results in increased mutagenesis of TP53 gene15240786
D020106AcrylamideAcrylamide results in increased phosphorylation of and results in increased expression of TP53 protein19426797
C106812adefovir dipivoxiladefovir dipivoxil affects the activity of TP53 protein25596134
D000255Adenosine TriphosphateTP53 protein inhibits the reaction [Deoxyglucose results in decreased abundance of Adenosine Triphosphate]21042727
D016604Aflatoxin B1Aflatoxin B1 affects the expression of TP53 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of TP53 mRNA28943387
D016604Aflatoxin B1Aflatoxin B1 results in increased activity of TP53 protein20655369
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of TP53 protein22100608
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of TP53 gene28458013
D016604Aflatoxin B1Aflatoxin B1 results in increased mutagenesis of TP53 gene12619106|1594649
D016604Aflatoxin B1CYP3A4 protein promotes the reaction [Aflatoxin B1 results in increased activity of TP53 protein]20655369
D016604Aflatoxin B1TP53 protein affects the reaction [Aflatoxin B1 results in increased expression of BTG2 mRNA]22100608
D016604Aflatoxin B1TP53 protein affects the reaction [Aflatoxin B1 results in increased expression of FDXR mRNA]22100608
D016604Aflatoxin B1TP53 protein affects the reaction [Aflatoxin B1 results in increased expression of PPM1D mRNA]22100608
D016604Aflatoxin B1TP53 protein affects the reaction [Aflatoxin B1 results in increased expression of TP53I3 mRNA]22100608
D016604Aflatoxin B1TP53 protein affects the reaction [Aflatoxin B1 results in increased phosphorylation of H2AFX protein]28882572
D016604Aflatoxin B1TP53 protein affects the susceptibility to Aflatoxin B128882572
D016604Aflatoxin B1Acetylcysteine inhibits the reaction [Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression of TP53 protein]]28181396
D016604Aflatoxin B1Acetylcysteine inhibits the reaction [Aflatoxin B1 results in increased expression of TP53 protein]28181396
D016604Aflatoxin B1Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Aflatoxin B1 results in increased expression of TP53 protein]]28181396
D016604Aflatoxin B1Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression of TP53 protein]28181396
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of TP53 mRNA28442411
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of TP53 protein28181396|9163691
D016604Aflatoxin B1fumonisin B1 promotes the reaction [Aflatoxin B1 results in increased expression of TP53 protein]28181396
C027955aflatoxin G1aflatoxin G1 results in increased activity of TP53 protein23907605
C027955aflatoxin G1aflatoxin G1 results in increased expression of TP53 protein modified form23907605
C027955aflatoxin G1Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of TP53 protein modified form]23907605
C027955aflatoxin G1Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of TP53 protein modified form]23907605
D000348AflatoxinsAflatoxins results in increased mutagenesis of TP53 gene16007211
C031143AICA ribonucleotide[resveratrol co-treated with AICA ribonucleotide] inhibits the reaction [Glucose results in increased expression of TP53 protein]26188290
D000393Air PollutantsAir Pollutants analog results in decreased expression of TP53 mRNA21757418
D000393Air PollutantsAir Pollutants results in decreased methylation of TP53 exon21756780
D000393Air PollutantsAir Pollutants results in increased methylation of TP53 promoter21756780
D000393Air PollutantsAir Pollutants results in increased mutagenesis of TP53 exon21756780
D000393Air PollutantsAir Pollutants results in increased expression of TP53 protein28389379
D000395Air Pollutants, Occupational"Air Pollutants, Occupational affects the expression of TP53 mRNA"20886531
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased expression of TP53 mRNA"23195993
C004363alantolactonealantolactone results in increased expression of TP53 protein22721982
D000420AlbuterolAlbuterol results in increased expression of TP5311802967
D000447AldehydesAldehydes results in decreased expression of TP53 mRNA25014914
D000487AllethrinAllethrin affects the expression of TP53 protein22356257
D000487AllethrinAllethrin results in decreased expression of TP53 mRNA23595975
D000487AllethrinAllethrin results in increased expression of TP53 mRNA25072698
C006453alliinalliin promotes the reaction [FGF2 protein results in increased expression of TP53 protein]16351512
C002055alloseallose results in increased expression of TP53 mRNA18930000
C002055alloseallose results in increased expression of TP53 protein18930000
C002055alloseFluorouracil promotes the reaction [allose results in increased expression of TP53 protein]18930000
C038491allyl sulfideallyl sulfide results in increased expression of TP53 mRNA24650757
C038491allyl sulfide[allyl sulfide co-treated with Diethylstilbestrol] results in increased expression of TP53 mRNA17125941
C038491allyl sulfideallyl sulfide results in increased expression of TP53 mRNA17125941
C518327aloe emodinaloe emodin results in increased expression of TP53 protein19928967
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in increased expression of TP53 protein28070108
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Quercetin analog results in decreased phosphorylation of TP53 protein]"23907460
C040534alpha-hexachlorocyclohexanealpha-hexachlorocyclohexane results in decreased expression of TP53 mRNA16940010
C040534alpha-hexachlorocyclohexanealpha-hexachlorocyclohexane results in increased expression of TP53 mRNA16940010
C011512alpha-naphthoflavonealpha-naphthoflavone results in increased expression of TP53 protein29274324
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [leptomycin B results in increased expression of TP53 protein]]15459018
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 mRNA]12126965
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 protein]12126965
D024502alpha-Tocopherol[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TP53 protein]16401635
D024502alpha-Tocopherol[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of TP53 protein]16401635
C120793alsterpaullonealsterpaullone affects the localization of TP53 protein16055726
C120793alsterpaullonealsterpaullone results in decreased degradation of and results in increased expression of TP53 protein16055726
C005197alternariolalternariol results in increased expression of TP53 protein22542754
C104223aluminum lactatealuminum lactate results in increased expression of TP53 mRNA19464335
C104223aluminum lactatealuminum lactate results in increased expression of TP53 protein19464335|2694460
C104223aluminum lactateQuercetin inhibits the reaction [aluminum lactate results in increased expression of TP53 protein]26944603
C067527aluminum maltolatealuminum maltolate results in decreased expression of TP53 mRNA24878590
C067527aluminum maltolatealuminum maltolate results in decreased expression of TP53 protein24878590
D000537Aluminum OxideAluminum Oxide analog results in increased expression of TP53 mRNA23132795
C077990alvocidibalvocidib results in decreased expression of TP53 protein9808574
C077990alvocidibalvocidib results in increased expression of TP53 protein10537362|1258903
C077990alvocidib[alvocidib results in increased expression of TP53 protein] which results in increased expression of CDKN1B protein12589031
C077990alvocidib[docetaxel co-treated with alvocidib] results in increased expression of TP53 protein15297405
C077990alvocidibalvocidib results in increased expression of TP53 protein15180955
D000577AmidesAmides results in increased expression of TP53 mRNA23063670
D000577AmidesAmides results in increased expression of TP53 protein23063670
D004999Amifostine[Amifostine co-treated with TP53] results in increased expression of MYC mRNA14555708
D004999AmifostineAmifostine results in increased activity of TP53 protein16628227
D004999AmifostineAmifostine results in increased expression of TP53 protein12618886
D004999Amifostineolomoucine inhibits the reaction [TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]]16628227
D004999AmifostineTP53 affects the susceptibility to Amifostine12618886
D004999AmifostineTP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]16628227
D000602Amino Acids, Peptides, and Proteins"Amino Acids, Peptides, and Proteins results in increased expression of TP53 mRNA"23747718
D000585AminacrineAminacrine results in increased stability of and results in increased activity of TP53 protein16177561
D000622Aminolevulinic AcidAminolevulinic Acid analog results in increased expression of TP5317311614
D006710HomocysteineHomocysteine results in increased phosphorylation of TP53 protein13679428
D0150812-Naphthylamine2-Naphthylamine results in decreased expression of TP53 mRNA18247414
D000643Ammonium ChlorideAmmonium Chloride affects the expression of TP53 mRNA16483693
D000643Ammonium ChlorideAmmonium Chloride results in increased expression of TP53 protein16483693
D000655AmodiaquineAmodiaquine affects the expression of TP53 protein24113242
D000655AmodiaquineAmodiaquine results in increased activity of TP53 protein12082016
D000677AmsacrineAmsacrine analog results in increased activity of TP53 protein12082016
D000677AmsacrineAmsacrine results in increased expression of TP53 protein11774253
D000677AmsacrineAmsacrine results in increased glutathionylation of TP53 protein17555331
D000677AmsacrineAmsacrine results in increased stability of and results in increased activity of TP53 protein16177561
C088115anacardic acidanacardic acid inhibits the reaction [[Fluorouracil results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein]27129209
C088115anacardic acidanacardic acid inhibits the reaction [Genistein promotes the reaction [trichostatin A results in increased acetylation of TP53 protein]]26768552
D000728AndrogensTP53 protein inhibits the reaction [Androgens results in increased expression of NKX3-1 mRNA]17202838
C030419andrographolideandrographolide results in increased expression of and results in increased phosphorylation of TP53 protein18619950
C030419andrographolideandrographolide results in increased expression of TP5319097688
C030419andrographolideFluorouracil promotes the reaction [andrographolide results in increased expression of TP53]19097688
D000841AnisomycinAnisomycin promotes the reaction [Colistin results in increased expression of TP53 protein]28842171
C540917anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione"anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione results in increased expression of TP53 protein"19146838
C540917anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione"TP53 protein promotes the reaction [anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione results in increased cleavage of CASP7 protein]"19146838
D000970Antineoplastic AgentsAntineoplastic Agents results in increased activity of TP53 protein22010212
D000970Antineoplastic AgentsTP53 protein promotes the reaction [Methotrexate results in increased susceptibility to Antineoplastic Agents]22010212
C034321aphantoxinaphantoxin results in increased expression of TP53 mRNA21710505
C102351apicidinapicidin results in decreased expression of TP53 mRNA19070610
C102351apicidinapicidin results in decreased expression of TP53 protein19070610
D047310ApigeninApigenin results in increased expression of TP53 protein16023288
D047310ApigeninTP53 protein affects the reaction [Apigenin results in increased expression of CDKN1A protein]11790449
D001115Arecoline[[Arecoline results in decreased expression of CDC25C] co-treated with [Arecoline results in increased expression of TP53]] results in decreased activity of CDK1 protein22108589
D001115ArecolineArecoline results in increased expression of TP53 protein22108589
C047981arginyl-glycyl-aspartic acidarginyl-glycyl-aspartic acid inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]16790523
D034341Aristolochic AcidsAcetylcysteine inhibits the reaction [Aristolochic Acids results in increased phosphorylation of TP53 protein]24792323
D034341Aristolochic AcidsAristolochic Acids results in increased phosphorylation of TP53 protein24792323
D001151ArsenicArsenic affects the expression of TP53 mRNA18414638
D001151ArsenicArsenic affects the expression of TP53 protein17450239
D001151ArsenicArsenic results in decreased expression of TP53 mRNA19945496
D001151ArsenicArsenic results in decreased expression of TP53 protein28785074
D001151ArsenicArsenic results in decreased methylation of TP53 exon21756780
D001151ArsenicArsenic results in decreased phosphorylation of TP53 protein24473091
D001151ArsenicArsenic results in increased expression of TP53 mRNA27122327
D001151ArsenicArsenic results in increased expression of TP53 protein23174854
D001151ArsenicArsenic results in increased expression of TP53 protein mutant form12899209
D001151ArsenicArsenic results in increased methylation of TP53 promoter16251483|2175678
D001151ArsenicArsenic results in increased mutagenesis of TP53 exon21756780|2677215
D001151ArsenicArsenic results in increased mutagenesis of TP53 gene15967209|1745023
D001151ArsenicTP53 gene mutant form results in increased susceptibility to Arsenic23643801
D001151ArsenicTP53 gene polymorphism results in increased susceptibility to Arsenic16930632
D001151ArsenicTP53 polymorphism affects the susceptibility to Arsenic21982800
D001151ArsenicArsenic results in increased mutagenesis of TP53 gene19203779
D001151ArsenicArsenic results in increased mutagenesis of TP53 gene19203779
C058317arsenic disulfide[arsenic disulfide results in decreased expression of SIRT1 protein] which results in increased expression of TP53 protein18298901
C058317arsenic disulfidearsenic disulfide results in increased expression of and results in increased phosphorylation of TP53 protein18298901
C058317arsenic disulfidesirtinol promotes the reaction [arsenic disulfide results in increased expression of and results in increased phosphorylation of TP53 protein]18298901
C058317arsenic disulfidewortmannin promotes the reaction [arsenic disulfide results in increased expression of and results in increased phosphorylation of TP53 protein]18298901
C006632arsenic trioxidearsenic trioxide results in increased expression of TP53 mRNA28454103
C006632arsenic trioxidearsenic trioxide results in increased expression of TP53 protein28454103
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of TP53 protein]15904916
C006632arsenic trioxidearsenic trioxide affects the expression of TP5311775218
C006632arsenic trioxide[arsenic trioxide co-treated with Curcumin] results in increased expression of TP53 protein27430728
C006632arsenic trioxide[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of TP53 mRNA24738333
C006632arsenic trioxide[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of TP53 protein24738333
C006632arsenic trioxide[arsenic trioxide co-treated with PML protein] results in increased expression of TP5320377131
C006632arsenic trioxidearsenic trioxide promotes the reaction [tetraarsenic tetrasulfide results in increased expression of TP53 protein]26110921
C006632arsenic trioxidearsenic trioxide results in decreased expression of TP53 mRNA27825931
C006632arsenic trioxidearsenic trioxide results in decreased expression of TP53 protein mutant form21454520
C006632arsenic trioxidearsenic trioxide results in increased degradation of TP53 protein19457607
C006632arsenic trioxidearsenic trioxide results in increased expression of and results in increased activity of TP53 protein17064470|1816719
C006632arsenic trioxidearsenic trioxide results in increased expression of TP53 mRNA10850458|1753043
C006632arsenic trioxidearsenic trioxide results in increased expression of TP53 protein10841286|1085045
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of and results in increased stability of TP53 protein25574600
C006632arsenic trioxideGH1 protein promotes the reaction [arsenic trioxide results in increased expression of TP53 mRNA]23851143
C006632arsenic trioxidetetraarsenic tetrasulfide promotes the reaction [arsenic trioxide results in increased expression of TP53 protein]26110921
C006632arsenic trioxideTP53 affects the susceptibility to arsenic trioxide12851490
C006632arsenic trioxideTP53 protein affects the reaction [arsenic trioxide results in increased expression of TNFRSF10B protein]12851490
C006632arsenic trioxideTP53 protein affects the reaction [arsenic trioxide results in increased expression of TNFSF10 protein]12851490
C006632arsenic trioxideTP53 protein inhibits the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]12851490
C006632arsenic trioxideTP53 protein inhibits the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of CASP3 protein]12851490
C006632arsenic trioxideTP53 protein mutant form results in decreased susceptibility to arsenic trioxide21454520|2488480
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of TP53 protein27638049
C006632arsenic trioxideATF4 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of TP53 protein]27638049
C006632arsenic trioxide2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [arsenic trioxide results in increased phosphorylation of TP53 protein]23337567
C006632arsenic trioxidearsenic trioxide results in increased activity of TP53 protein17487067
C006632arsenic trioxidearsenic trioxide results in increased expression of TP53 mRNA21145380|2280107
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of TP53 protein23337567
C006632arsenic trioxidepifithrin inhibits the reaction [arsenic trioxide results in increased activity of TP53 protein]17487067
C006632arsenic trioxidearsenic trioxide results in increased expression of TP5313129816
C015001arsenite3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]20199942
C015001arseniteAcetylcysteine inhibits the reaction [arsenite results in increased expression of TP53 protein]22260869
C015001arsenitealpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 mRNA]12126965
C015001arsenitealpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 protein]12126965
C015001arsenitearsenite affects the methylation of TP53 promoter11489357
C015001arsenitearsenite promotes the reaction [TP53 protein binds to CREBBP protein]20199942
C015001arsenitearsenite promotes the reaction [TP53 protein binds to MIR34A promoter]25281835
C015001arsenitearsenite promotes the reaction [TP53 protein binds to SIRT1 promoter]25281835
C015001arsenite[[arsenite results in increased activity of PRKDC protein] which results in increased phosphorylation of and results in increased activity of MAPK9 protein] promotes the reaction [MAPK9 protein binds to TP53 protein]22366412
C015001arsenite[[[arsenite results in increased activity of PRKDC protein] which results in increased phosphorylation of and results in increased activity of MAPK9 protein] promotes the reaction [MAPK9 protein binds to TP53 protein]] inhibits the reaction [MDM2 results in increased degradation of and results in decreased stability of TP53 protein]22366412
C015001arsenitearsenite results in increased expression of and results in increased acetylation of TP53 protein25281835
C015001arsenitearsenite results in increased expression of TP53 mRNA12126965|2226086
C015001arsenitearsenite results in increased expression of TP53 protein12126965|2226086
C015001arsenitearsenite results in increased phosphorylation of and results in increased localization of and results in increased activity of TP53 protein20199942
C015001arseniteHSPA9 protein inhibits the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]20199942
C015001arseniteHSPA9 protein inhibits the reaction [arsenite results in increased phosphorylation of and results in increased localization of and results in increased activity of TP53 protein]20199942
C015001arseniteHSPA9 protein promotes the reaction [3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]]20199942
C015001arseniteRELA protein inhibits the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]20199942
C015001arseniteRELA protein inhibits the reaction [arsenite results in increased phosphorylation of and results in increased localization of and results in increased activity of TP53 protein]20199942
C015001arseniteTP53 mutant form inhibits the reaction [arsenite results in increased activity of CASP3 protein]22260869
C015001arseniteTP53 mutant form inhibits the reaction [arsenite results in increased activity of CASP7 protein]22260869
C015001arseniteTP53 mutant form inhibits the reaction [arsenite results in increased cleavage of PARP1 protein]22260869
C078098ar-turmeronear-turmerone results in increased expression of TP53 mRNA19250610
C078098ar-turmeronear-turmerone results in increased expression of TP53 protein19250610
D001194AsbestosAsbestos affects the localization of TP53 protein25466987
D001194AsbestosTP53 gene SNP affects the susceptibility to Asbestos23435014
D017639Asbestos, Amosite"Asbestos, Amosite affects the localization of TP53 protein"16357363
D017639Asbestos, Amosite"Asbestos, Amosite results in increased expression of TP53 mRNA"16357363
D017639Asbestos, Amosite"Asbestos, Amosite results in increased expression of TP53 protein"16357363
D017639Asbestos, Amosite"Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]"16357363
D017639Asbestos, Amosite"Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]"16357363
D017639Asbestos, Amosite"Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 protein]"16357363
D017639Asbestos, Amosite"pifithrin inhibits the reaction [Asbestos, Amosite affects the localization of TP53 protein]"16357363
D017639Asbestos, Amosite"pifithrin inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 protein]"16357363
D017639Asbestos, Amosite"Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]"16357363
D017639Asbestos, Amosite"TP53 protein results in increased susceptibility to Asbestos, Amosite"16357363
D017639Asbestos, Amosite"Asbestos, Amosite results in increased expression of TP53 protein"16357363
D017639Asbestos, Amosite"Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 protein]"16357363
D017636Asbestos, Amphibole"Asbestos, Amphibole affects the expression of TP53 protein"20855422
D017636Asbestos, Amphibole"Asbestos, Amphibole results in increased phosphorylation of and results in increased stability of TP53 protein"20705543
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of TP53 mRNA"17331233
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of TP53 protein"21570478
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in decreased expression of and results in increased phosphorylation of TP53 protein"23634900
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in decreased expression of TP53 protein"23634900
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in decreased expression of TP53 protein modified form"21570478
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of TP53 protein"12676607
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased phosphorylation of and results in increased stability of TP53 protein"20705543
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased phosphorylation of TP53 protein"12676607
D001205Ascorbic AcidAcetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
D001205Ascorbic Acid[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein20530418
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]20067818
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein]25977998
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein modified form]25977998
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of TP53 mRNA]22245848
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of TP53 protein]22245848
D001205Ascorbic AcidAscorbic Acid promotes the reaction [Cisplatin results in increased expression of TP53 protein]21429301
D001205Ascorbic Acidbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
D001205Ascorbic Acidnutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
D001205Ascorbic Acid[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TP53 protein]16401635
D001205Ascorbic Acid[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of TP53 protein]16401635
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]20067818
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of and results in increased phosphorylation of TP53 protein]21262251
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of TP53 mRNA]21262251
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Potassium Dichromate results in increased localization of TP53 protein modified form]21262251
D001241AspirinAspirin inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]10942736
D001241AspirinAspirin results in increased acetylation of TP53 protein19212664
D001241AspirinAspirin results in increased expression of TP53 protein12535653
C005948astaxanthineastaxanthine inhibits the reaction [Cyclophosphamide results in increased expression of TP53 protein]20038455
C026304atranorinatranorin results in decreased expression of TP53 protein22285236
C098644atrasentanatrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]22431579
D001280AtrazineAtrazine results in decreased expression of TP53 mRNA21333729|2237831
D001280AtrazineAtrazine results in decreased expression of TP53 protein21333729
D001280Atrazinekolaviron inhibits the reaction [Atrazine results in decreased expression of TP53 mRNA]21333729
D001280Atrazinekolaviron inhibits the reaction [Atrazine results in decreased expression of TP53 protein]21333729
D001280AtrazineAtrazine affects the expression of TP5321726175
D001280AtrazineAtrazine affects the localization of TP53 protein9486943
D001280AtrazineAtrazine results in increased expression of TP53 protein9486943
D001280Atrazinekolaviron inhibits the reaction [Atrazine affects the expression of TP53]21726175
D001285AtropineAtropine inhibits the reaction [Malathion results in increased expression of TP53 protein]12762645
D001285AtropineAtropine inhibits the reaction [Parathion results in increased expression of TP53 protein]12762645
C083578aurofusarinaurofusarin results in increased expression of TP53 protein29248571
D001374AzacitidineAzacitidine results in increased expression of TP53 protein15547111
D001374Azacitidinepifithrin inhibits the reaction [Azacitidine results in increased expression of TP53 protein]15547111
D001374AzacitidineTP53 protein promotes the reaction [Azacitidine results in decreased expression of DNMT1 mRNA]15547111
D001374AzacitidineTP53 protein promotes the reaction [Azacitidine results in decreased expression of DNMT3A mRNA]15547111
D001374AzacitidineTP53 protein promotes the reaction [Azacitidine results in increased expression of GADD45A mRNA]15547111
D001374AzacitidineTP53 protein promotes the reaction [Azacitidine results in increased expression of GADD45A protein]15547111
D001374AzacitidineTP53 protein results in increased susceptibility to Azacitidine15547111
C010329azadirachtinazadirachtin results in increased expression of TP53 mRNA20429769
C010329azadirachtinazadirachtin results in increased expression of TP53 protein20429769
D001379AzathioprineAzathioprine results in increased expression of TP53 protein14961032
D001379AzathioprineAzathioprine results in increased mutagenesis of TP53 gene17979968
D001397AzoxymethaneAzoxymethane results in increased phosphorylation of TP53 protein18239060
C040929bafilomycin A1[bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein23380477
C040929bafilomycin A1bafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein]23380477
C006680baicaleinbaicalein results in increased expression of TP53 protein21457722
C038044baicalinbaicalin results in increased expression of TP53 protein21457722
C002478bathocuproinebathocuproine inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
C002478bathocuproinebathocuproine inhibits the reaction [[phenylhydroquinone co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
C028559bathocuproine sulfonatebathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein]11964141
C416282BAY 11-7085BAY 11-7085 inhibits the reaction [7-ketocholesterol results in increased expression of TP53 protein]25845326
C580697BDMC-ABDMC-A results in increased expression of TP53 protein24365254
C487081belinostatbelinostat results in decreased expression of TP53 mRNA19606018
D000069461Bendamustine HydrochlorideBendamustine Hydrochloride results in increased expression of TP53 protein12948851
D001546BentoniteBentonite inhibits the reaction [[HT-2 toxin co-treated with T-2 Toxin] results in increased expression of TP53 mRNA]25296281
D001551Benz(a)AnthracenesBenz(a)Anthracenes analog results in increased phosphorylation of TP53 protein18205319
D001554BenzeneBenzene results in decreased expression of TP53 mRNA19505915
D001554BenzeneBenzene results in increased expression of TP53 mRNA21382456
D001554BenzeneBenzene results in increased mutagenesis of TP53 gene19862502
D001554BenzeneBenzene results in increased phosphorylation of TP53 protein8076368
D001554BenzeneTP53 gene SNP results in increased susceptibility to Benzene16728435
D001554BenzeneTP53 SNP affects the susceptibility to Benzene18978339
D001554BenzeneBenzene results in increased expression of TP53 protein18093815
D001554BenzeneBenzene results in increased phosphorylation of and results in increased activity of TP53 protein9118908
D001554BenzeneBenzene results in increased phosphorylation of TP53 protein8076368
C029876benzidinebenzidine results in increased expression of TP53 protein mutant form15748509|1769052
C017228benzo(a)pyrene 7,8-dihydrodiol"benzo(a)pyrene 7,8-dihydrodiol results in increased expression of and results in increased phosphorylation of TP53 protein"15698582
C072019benzo(a)pyrene diolepoxide Ibenzo(a)pyrene diolepoxide I promotes the reaction [TP53 protein binds to POLH promoter]27694624
C072019benzo(a)pyrene diolepoxide Ibenzo(a)pyrene diolepoxide I results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein27694624
C072019benzo(a)pyrene diolepoxide Ibenzo(a)pyrene diolepoxide I results in increased expression of and results in increased phosphorylation of TP53 protein15698582
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of TP53 protein21776270
D019324beta-Naphthoflavone[beta-Naphthoflavone binds to and results in increased activity of AHR protein] results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]22044530
C100422benzo(g)chrysenebenzo(g)chrysene results in increased phosphorylation of TP53 protein17961608
D001564Benzo(a)pyrene"2,4,4'-trichlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein]"20840854
D001564Benzo(a)pyrene"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene affects the localization of and results in increased expression of TP53 protein]"24954032
D001564Benzo(a)pyrene"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein]"20840854
D001564Benzo(a)pyrene"2,4,5,2',5'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]"20840854
D001564Benzo(a)pyrene"2,4,5,2',5'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein]"20840854
D001564Benzo(a)pyrene"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene affects the localization of TP53 protein]"20840854
D001564Benzo(a)pyrene"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein]"20840854
D001564Benzo(a)pyreneAcrolein inhibits the reaction [Benzo(a)pyrene results in increased activity of TP53 protein]12807757
D001564Benzo(a)pyreneBenzo(a)pyrene affects the activity of TP53 protein20624995
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of TP5324362009
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of TP53 mRNA21393351|2782593
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of TP53 mutant form24362009
D001564Benzo(a)pyreneBenzo(a)pyrene affects the localization of and results in increased expression of TP53 protein24954032
D001564Benzo(a)pyreneBenzo(a)pyrene affects the localization of TP53 protein20840854
D001564Benzo(a)pyreneBenzo(a)pyrene affects the phosphorylation of TP53 protein24362009
D001564Benzo(a)pyreneBenzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]15625077
D001564Benzo(a)pyreneBenzo(a)pyrene promotes the reaction [TP53 protein results in increased expression of CYP2A6 mRNA]26343999
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of TP53 mRNA18247414
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of TP53 protein29126329
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased activity of TP53 protein12807757
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of and results in increased phosphorylation of TP53 protein15698582
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TP53 mRNA19027820|2288981
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TP53 protein10837373|1178236
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TP53 protein modified form22044530
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased mutagenesis of TP53 gene22319594
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased phosphorylation of and results in increased activity of TP53 protein24664296
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein20840854|2145777
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased phosphorylation of TP53 protein15837074|2436149
D001564Benzo(a)pyrene[Buthionine Sulfoximine results in decreased abundance of Glutathione] inhibits the reaction [Benzo(a)pyrene results in increased activity of TP53 protein]12807757
D001564Benzo(a)pyreneCadmium Chloride affects the reaction [Benzo(a)pyrene results in increased phosphorylation of TP53 protein]25744307
D001564Benzo(a)pyreneCurcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased activity of TP53 protein]24664296
D001564Benzo(a)pyreneEstradiol promotes the reaction [Benzo(a)pyrene affects the localization of and results in increased expression of TP53 protein]24954032
D001564Benzo(a)pyrenefluoranthene promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]22120587
D001564Benzo(a)pyrenefostriecin promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]24954032
D001564Benzo(a)pyreneFOXO3 mutant form promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]24954032
D001564Benzo(a)pyreneMDM2 mutant form promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]20840854
D001564Benzo(a)pyreneNitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]16041517
D001564Benzo(a)pyreneOkadaic Acid affects the reaction [Estradiol promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]24954032
D001564Benzo(a)pyreneOkadaic Acid affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]24954032
D001564Benzo(a)pyrene"Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]"24954032
D001564Benzo(a)pyreneOkadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]24954032
D001564Benzo(a)pyrene"Okadaic Acid promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]"24954032
D001564Benzo(a)pyrenePARG affects the reaction [Benzo(a)pyrene results in increased expression of TP53 mRNA]22266578
D001564Benzo(a)pyrenePARG affects the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]22266578
D001564Benzo(a)pyrenepifithrin inhibits the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]16258175
D001564Benzo(a)pyreneR18 peptide promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]24954032
D001564Benzo(a)pyreneSimvastatin promotes the reaction [Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]]15625077
D001564Benzo(a)pyreneTetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene affects the localization of and results in increased expression of TP53 protein]24954032
D001564Benzo(a)pyreneTP53 affects the reaction [Benzo(a)pyrene results in increased expression of BAX mRNA]10837373
D001564Benzo(a)pyreneTP53 affects the reaction [Benzo(a)pyrene results in increased expression of MDM2 mRNA]10837373
D001564Benzo(a)pyreneTP53 affects the susceptibility to Benzo(a)pyrene10837373
D001564Benzo(a)pyreneTP53 mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CDKN1A mRNA]24361490
D001564Benzo(a)pyreneTP53 mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CGB3 mRNA]24361490
D001564Benzo(a)pyreneTP53 mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of ERVFRD-1 mRNA]24361490
D001564Benzo(a)pyreneTP53 protein affects the reaction [Benzo(a)pyrene results in increased expression of CDKN1A mRNA]28882572
D001564Benzo(a)pyreneTP53 protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]25398514
D001564Benzo(a)pyreneTP53 protein affects the reaction [Benzo(a)pyrene results in increased phosphorylation of H2AFX protein]28882572
D001564Benzo(a)pyreneTP53 protein affects the susceptibility to Benzo(a)pyrene28882572
D001564Benzo(a)pyrene[TP53 protein binds to CYP1A1 promoter] affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]25398514
D001564Benzo(a)pyreneTP53 protein promotes the reaction [Benzo(a)pyrene results in decreased expression of BRCA1 mRNA]11782367
D001564Benzo(a)pyreneTP53 protein results in increased susceptibility to Benzo(a)pyrene25398514
D001564Benzo(a)pyreneVitamin E inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased activity of TP53 protein]24664296
D001564Benzo(a)pyreneVitamin E inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of TP53 protein]15837074
D001564Benzo(a)pyrenewortmannin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of TP53 protein]15837074
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased mutagenesis of TP53 gene22410783
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TP53 mRNA18656336
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TP53 mRNA21899289
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of TP53 mRNA28651000
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of and results in increased phosphorylation of TP53 protein15459018
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TP53 mRNA19408242|2006408
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TP53 protein19408242|2006408
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TP53 protein modified form21604763
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased phosphorylation of TP53 protein17961608|1863486
D001564Benzo(a)pyrene[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 mRNA19408242
D001564Benzo(a)pyrene[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 protein19408242
D001564Benzo(a)pyreneSulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 mRNA]20064080
D001564Benzo(a)pyreneSulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]20064080
D001564Benzo(a)pyreneTetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of and results in increased phosphorylation of TP53 protein]15459018
D001564Benzo(a)pyrene[TNF protein co-treated with Benzo(a)pyrene] results in increased phosphorylation of TP53 protein21745554
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased activity of TP53 protein22044530
D001564Benzo(a)pyrenepifithrin results in decreased susceptibility to [Benzo(a)pyrene results in increased activity of TP53 protein]22044530
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TP53 protein]"18085531
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide binds to TP53 gene"12727806
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of and results in increased phosphorylation of and results in increased localization of and results in increased activity of TP53 protein"18085531
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of and results in increased phosphorylation of TP53 protein"21983885
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TP53 mRNA"19150397
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TP53 protein"11782367|2038263
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of TP53 protein"20382639
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"monomethylarsonous acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of and results in increased phosphorylation of and results in increased localization of and results in increased activity of TP53 protein]"18085531
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"potassium chromate(VI) promotes the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide binds to TP53 gene]"12727806
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"TP53 protein affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of CASP7 protein]"21983885
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"TP53 protein affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of CASP9 protein]"21983885
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"TP53 protein affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TP53 protein]"21983885
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"TP53 protein affects the susceptibility to 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"21983885
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"TP53 protein promotes the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of BRCA1 mRNA]"11782367
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"TP53 protein promotes the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of BRCA1 protein]"11782367
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased mutagenesis of TP53 gene"21428456
C110772benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [TP53 protein affects the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]]16166740
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Bortezomib results in increased phosphorylation of TP53 protein]12393500
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in increased degradation of TP53 protein]19699254
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chlorpyrifos results in decreased expression of TP53 protein]27993609
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of TP53 protein mutant form]21454520
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]18951928
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of TP53 protein27129209
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 protein10837373
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]16330492
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]26612707
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 protein modified form26612707
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of and results in increased expression of TP53 protein18463101
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of TP53 protein18463101
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidTP53 gene mutant form affects the reaction [benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AFX protein]]26544897
D001599Berberine[Berberine co-treated with Niacinamide] results in increased expression of and results in increased acetylation of TP53 protein26712469
D001599BerberineBerberine results in increased expression of TP53 mRNA20656010
D001599BerberineBerberine results in increased expression of TP53 protein20656010
D001599BerberineBerberine results in increased phosphorylation of and results in increased acetylation of TP53 protein26712469
C020711beryllium sulfateberyllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]17395767
C020711beryllium sulfateberyllium sulfate results in increased expression of TP53 protein17395767|2097470
C000617228beta-2-himachalen-6-olbeta-2-himachalen-6-ol results in increased expression of TP53 protein28782499
D019207beta Carotene[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TP53 protein]16401635
D019207beta Carotene[beta Carotene co-treated with alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of TP53 protein]16401635
D004958EstradiolEstradiol affects the expression of TP53 mRNA24349563
D004958EstradiolEstradiol affects the expression of TP53 mRNA22574217
D004958EstradiolEstradiol affects the localization of and results in decreased activity of TP53 protein15870704
D004958Estradiol[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of TP53 protein22534328
D004958Estradiol[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of TP53 protein22534328
D004958EstradiolEstradiol inhibits the reaction [TP53 protein binds to MIR34B promoter]22113133
D004958EstradiolEstradiol promotes the reaction [Benzo(a)pyrene affects the localization of and results in increased expression of TP53 protein]24954032
D004958Estradiol"Estradiol promotes the reaction [dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein]"24954032
D004958EstradiolEstradiol results in increased expression of and results in increased activity of and affects the localization of TP53 protein16053526
D004958EstradiolEstradiol results in increased expression of TP53 mRNA23804311
D004958EstradiolEstradiol results in increased expression of TP53 protein18174961|1964773
D004958Estradiolfulvestrant inhibits the reaction [Estradiol affects the localization of TP53 protein]15870704
D004958Estradiol[Lindane co-treated with Estradiol] results in increased expression of TP53 protein18174961
D004958EstradiolOkadaic Acid affects the reaction [Estradiol promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]24954032
D004958Estradiol[Parathion co-treated with Estradiol] results in increased expression of TP53 protein mutant form17622325
D004958EstradiolEstradiol results in increased expression of TP53 mRNA14595849
D004958Estradiol[Estradiol co-treated with Methylnitrosourea co-treated with Progesterone] results in decreased expression of TP53 mRNA20732338
D004958EstradiolEstradiol results in decreased expression of TP53 protein24894866
D004958EstradiolEstradiol results in increased expression of TP53 mRNA17522070
D004958EstradiolEstradiol results in increased expression of TP53 protein14685795
D004958Estradiolresveratrol inhibits the reaction [Estradiol results in decreased expression of TP53 protein]24894866
C014638beta-lapachonebeta-lapachone results in increased expression of TP53 mRNA22560901
C095105bexarotenebexarotene results in increased phosphorylation of and results in increased activity of TP53 protein19067706
C053541bicalutamidebicalutamide results in increased expression of TP53 protein15638997
D001647Bile Acids and SaltsBile Acids and Salts results in decreased expression of TP53 protein21127259
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) affects the localization of TP53 protein"21548882
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein"21548882
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"bromopyruvate promotes the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"Glucose inhibits the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"MAPK14 protein promotes the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"monomethyl succinate inhibits the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"PRKAA2 protein promotes the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) affects the localization of TP53 protein]"21548882
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"PRKAA2 protein promotes the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"SOD1 protein inhibits the reaction [bromopyruvate promotes the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]]"21548882
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"[Tretinoin results in increased uptake of Glucose] inhibits the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
C070515bisindolylmaleimide Ibisindolylmaleimide I results in decreased degradation of and results in increased expression of TP53 protein16055726
C467001bisindolylmaleimide IXbisindolylmaleimide IX results in decreased degradation of and results in increased expression of TP53 protein16055726
C006780bisphenol Abisphenol A results in increased expression of TP53 mRNA28159858
C006780bisphenol Abisphenol A affects the expression of TP53 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of TP53 mRNA26911650|2808373
C006780bisphenol Abisphenol A results in decreased expression of TP53 mRNA27998958|2823872
C006780bisphenol Abisphenol A results in decreased expression of TP53 protein23222814
C006780bisphenol Abisphenol A results in increased expression of TP53 mRNA29275510
C006780bisphenol Abisphenol A results in increased expression of TP53 protein21277958|2483173
C006780bisphenol Abisphenol A results in increased phosphorylation of TP53 protein29275510
C006780bisphenol ACurcumin inhibits the reaction [bisphenol A results in decreased expression of TP53 protein]23222814
C006780bisphenol ACurcumin inhibits the reaction [bisphenol A results in increased expression of TP53 protein]24831732
C006780bisphenol AMIR149 mRNA inhibits the reaction [bisphenol A results in decreased expression of TP53 mRNA]28238728
C006780bisphenol Abisphenol A affects the expression of TP53 mRNA17950039
C006780bisphenol Abisphenol A results in increased expression of TP53 mRNA14595849
C006780bisphenol Abisphenol A affects the expression of TP53 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of TP53 mRNA25181051
C006780bisphenol Abisphenol A results in decreased expression of TP53 mRNA26982218
C006780bisphenol Abisphenol A results in increased expression of TP53 mRNA23146694|2753935
C006780bisphenol Abisphenol A results in increased expression of TP53 protein25344109|2545464
C006780bisphenol Abisphenol A results in increased methylation of TP53 gene28505145
C006780bisphenol AMelatonin inhibits the reaction [bisphenol A results in increased expression of TP53 protein]25454643
C006780bisphenol Abisphenol A results in increased expression of TP53 protein28819136
C006780bisphenol Abisphenol A results in increased expression of TP53 mRNA20060579
D057886Bleaching AgentsBleaching Agents results in increased expression of TP53 mRNA21538407
D001761Bleomycin2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]]24933654
D001761Bleomycin2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of TP53 protein]24933654
D001761Bleomycin2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]]24933654
D001761BleomycinBleomycin promotes the reaction [Polyphenols results in increased expression of TP53 mRNA]26800624
D001761BleomycinBleomycin promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]24933654
D001761BleomycinBleomycin promotes the reaction [Tea results in increased expression of TP53 mRNA]26800624
D001761BleomycinBleomycin results in increased expression of TP53 mRNA26800624
D001761BleomycinBleomycin results in increased phosphorylation of TP53 protein24933654
D001761BleomycinPolyphenols promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]26800624
D001761Bleomycinresveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]24933654
D001761BleomycinTea promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]26800624
D001761BleomycinTP53 protein results in increased susceptibility to Bleomycin20135637
D000069286Bortezomibbenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Bortezomib results in increased phosphorylation of TP53 protein]12393500
D000069286BortezomibBortezomib promotes the reaction [TP53 protein binds to MDM2 protein]12393500
D000069286BortezomibBortezomib results in increased expression of TP53 protein12393500|1517309
D000069286BortezomibBortezomib results in increased phosphorylation of and results in increased localization of TP53 protein12393500
D000069286BortezomibBortezomib results in increased stability of TP53 protein15543232
D000069286BortezomibCaffeine inhibits the reaction [Bortezomib results in increased phosphorylation of TP53 protein]12393500
D000069286Bortezomib[CASP8 protein results in increased activity of CASP3 protein] affects the reaction [Bortezomib results in increased phosphorylation of TP53 protein]12393500
D000069286Bortezomib[irinotecan co-treated with Bortezomib] results in increased ubiquitination of TP53 protein16373703
D000069286BortezomibSCIO-469 promotes the reaction [Bortezomib results in increased expression of TP53 protein]16617327
D000069286BortezomibTP53 protein affects the susceptibility to [irinotecan co-treated with Bortezomib]16373703
D000069286Bortezomib[vorinostat co-treated with Bortezomib] results in increased expression of TP53 protein17351739
C555919BPC96 peptideBPC96 peptide results in increased expression of TP53 protein20708052
C023623brassinolidebrassinolide results in increased expression of TP53 protein20833159
D001959BromatesBromates results in increased phosphorylation of TP53 protein21864635
D001959Bromatesbromochloroacetic acid promotes the reaction [Bromates results in increased phosphorylation of TP53 protein]21864635
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TP5311802967
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TP53 protein10642304
C099813bromochloroacetic acidbromochloroacetic acid promotes the reaction [Bromates results in increased phosphorylation of TP53 protein]21864635
C017092bromopyruvate"bromopyruvate promotes the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
C017092bromopyruvate"SOD1 protein inhibits the reaction [bromopyruvate promotes the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]]"21548882
D019819BudesonideBudesonide results in decreased expression of TP53 protein15475437
D002065BuspironeBuspirone results in decreased expression of TP53 mRNA24136188
D002066BusulfanBusulfan affects the phosphorylation of and affects the activity of TP53 protein16882877
D019328Buthionine Sulfoximine[Buthionine Sulfoximine results in decreased abundance of Glutathione] inhibits the reaction [Benzo(a)pyrene results in increased activity of TP53 protein]12807757
D019328Buthionine Sulfoximine[cyanoginosin LR co-treated with Buthionine Sulfoximine] results in increased expression of TP53 protein25410294
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of TP53 protein25086368
D002083Butylated Hydroxyanisole[propylparaben co-treated with Butylated Hydroxyanisole] results in increased expression of TP53 protein25086368
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TP53 protein]18593901
D002084Butylated HydroxytolueneButylated Hydroxytoluene results in increased expression of TP53 mRNA9780227
D020122tert-ButylhydroperoxideNiacinamide inhibits the reaction [tert-Butylhydroperoxide results in increased expression of TP53 protein]12782109
D020122tert-ButylhydroperoxideS-ethyl glutathione inhibits the reaction [tert-Butylhydroperoxide results in increased expression of TP53 protein modified form]17555331
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of TP53 mRNA12419474
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of TP53 protein12782109
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased glutathionylation of TP53 protein17555331
C026105butylidenephthalidebutylidenephthalide results in increased expression of TP53 protein16987298
C026105butylidenephthalidebutylidenephthalide results in increased phosphorylation of TP53 protein16987298
C018475butyraldehydebutyraldehyde results in decreased expression of TP53 mRNA26079696
D002087ButyratesButyrates results in increased expression of TP53 protein15978324
D020148Butyric AcidButyric Acid results in decreased expression of and affects the localization of TP53 protein mutant form16598767
D020148Butyric Acid[1'-acetoxychavicol acetate co-treated with Butyric Acid] results in increased phosphorylation of TP53 protein24480522
C584509C646 compoundC646 compound results in decreased expression of TP53 mRNA26191083
C584509C646 compoundC646 compound results in increased expression of TP53 mRNA23698071
C584509C646 compoundC646 compound inhibits the reaction [AGT protein modified form promotes the reaction [TP53 protein binds to EP300 protein]]26612707
C584509C646 compoundC646 compound inhibits the reaction [AGT protein modified form results in increased acetylation of TP53 protein]26612707
D002101Cacodylic Acid[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TP53 mRNA23192986
D002101Cacodylic AcidCacodylic Acid results in increased expression of TP53 mRNA17720352
D002104CadmiumCadmium results in decreased expression of TP53 mRNA22768170
D002104CadmiumCadmium results in increased expression of TP53 mRNA25490952
D002104CadmiumNitric Oxide inhibits the reaction [Cadmium results in increased expression of TP53 mRNA]25490952
D002104Cadmiumspermine nitric oxide complex inhibits the reaction [Cadmium results in increased expression of TP53 mRNA]25490952
D002104CadmiumCadmium affects the localization of TP53 protein25101185
D002104CadmiumCadmium inhibits the reaction [Dactinomycin results in increased expression of and results in increased activity of TP53 protein]10531375
D002104CadmiumCadmium inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased activity of TP53 protein]10531375
D002104CadmiumCadmium inhibits the reaction [Methyl Methanesulfonate results in increased expression of and results in increased activity of TP53 protein]10531375
D002104CadmiumCadmium results in decreased folding of and results in decreased activity of TP53 protein10531375
D002104CadmiumCadmium results in increased expression of and results in increased phosphorylation of TP53 protein17174997
D002104CadmiumCadmium results in increased expression of TP53 protein12189181
D002104CadmiumTP53 protein affects the reaction [Cadmium affects the activity of APEX1 protein]21605570
D002104CadmiumTP53 protein affects the reaction [Cadmium affects the expression of APEX1 mRNA]21605570
D002104CadmiumTP53 protein affects the susceptibility to Cadmium17174997
D002104CadmiumCadmium results in increased expression of TP5324120750
D002104CadmiumCadmium results in increased expression of TP53 protein21467746|2309535
D002104CadmiumAcetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of TP53 protein]27658547
D002104CadmiumCadmium results in increased activity of TP53 protein16730872
D002104CadmiumCadmium results in increased expression of and results in increased phosphorylation of TP53 protein21467746
D002104CadmiumCadmium results in increased expression of and results in increased ubiquitination of TP53 protein18463101
D002104CadmiumCadmium results in increased expression of TP53 protein24212999
D002104CadmiumCadmium results in increased phosphorylation of TP53 protein18463101|2765854
D002104CadmiumCadmium results in increased expression of and results in increased phosphorylation of TP53 protein23095357
C028031cadmium acetatecadmium acetate results in decreased expression of TP53 mRNA18155341
C028031cadmium acetatecadmium acetate results in increased degradation of and affects the localization of TP53 protein15450950
C028031cadmium acetatecadmium acetate results in increased phosphorylation of TP53 protein20839231
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of TP53 mRNA25456234
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TP53 mRNA24839000|2503518
D019256Cadmium ChlorideSelenium inhibits the reaction [Cadmium Chloride results in increased expression of TP53 mRNA]25035189
D019256Cadmium ChlorideCadmium Chloride affects the activity of TP53 protein25596134
D019256Cadmium ChlorideCadmium Chloride affects the localization of TP53 protein25118938
D019256Cadmium ChlorideCadmium Chloride affects the phosphorylation of TP53 protein23941782
D019256Cadmium ChlorideCadmium Chloride affects the reaction [Benzo(a)pyrene results in increased phosphorylation of TP53 protein]25744307
D019256Cadmium ChlorideCadmium Chloride affects the reaction [Etoposide results in increased phosphorylation of TP53 protein]25744307
D019256Cadmium ChlorideCadmium Chloride affects the reaction [Fluorouracil affects the phosphorylation of TP53 protein]23941782
D019256Cadmium ChlorideCadmium Chloride affects the reaction [Fluorouracil results in increased expression of TP53 mRNA]23941782
D019256Cadmium ChlorideCadmium Chloride affects the reaction [Fluorouracil results in increased phosphorylation of TP53 protein]25744307
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [Dactinomycin results in increased expression of and results in increased activity of TP53 protein]10531375
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased activity of TP53 protein]10531375
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [Methyl Methanesulfonate results in increased expression of and results in increased activity of TP53 protein]10531375
D019256Cadmium ChlorideCadmium Chloride results in decreased activity of TP53 protein25446071
D019256Cadmium Chloride[Cadmium Chloride results in decreased activity of TP53 protein] inhibits the reaction [TP53 protein binds to TP53 gene]25446071|2544607
D019256Cadmium Chloride[Cadmium Chloride results in decreased activity of TP63 protein] inhibits the reaction [TP63 protein binds to TP53 gene]25446071
D019256Cadmium Chloride[Cadmium Chloride results in decreased activity of TP73 protein] inhibits the reaction [TP73 protein binds to TP53 gene]25446071
D019256Cadmium ChlorideCadmium Chloride results in decreased folding of and results in decreased activity of TP53 protein10531375
D019256Cadmium ChlorideCadmium Chloride results in increased expression of and results in increased phosphorylation of TP53 protein17174997|2511893
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TP53 mRNA23941782|2647268
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TP53 protein12676607|2511187
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of TP53 protein12676607
D019256Cadmium ChlorideDithiothreitol inhibits the reaction [[Cadmium Chloride results in decreased activity of TP53 protein] inhibits the reaction [TP53 protein binds to TP53 gene]]25446071|2544607
D019256Cadmium ChlorideEdetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP53 protein] inhibits the reaction [TP53 protein binds to TP53 gene]]25446071|2544607
D019256Cadmium ChlorideEdetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP63 protein] inhibits the reaction [TP63 protein binds to TP53 gene]]25446071
D019256Cadmium ChlorideEdetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP73 protein] inhibits the reaction [TP73 protein binds to TP53 gene]]25446071
D019256Cadmium ChlorideFluorouracil affects the reaction [Cadmium Chloride affects the phosphorylation of TP53 protein]23941782
D019256Cadmium ChlorideFluorouracil affects the reaction [Cadmium Chloride results in increased expression of TP53 mRNA]23941782
D019256Cadmium ChlorideTP53 protein affects the susceptibility to Cadmium Chloride17174997
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TP53 protein25111876
D019256Cadmium ChlorideCadmium Chloride affects the expression of TP53 mRNA10647914
D019256Cadmium ChlorideCadmium Chloride results in increased activity of TP53 protein16730872
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TP53 mRNA21181359|2340508
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TP53 protein16600092|1961543
D019256Cadmium Chlorideresveratrol inhibits the reaction [Cadmium Chloride results in increased expression of TP53 mRNA]24492640
D019256Cadmium ChlorideSelenium inhibits the reaction [Cadmium Chloride results in increased expression of TP53 protein]16600092
D019256Cadmium ChlorideCadmium Chloride results in increased expression of TP5319475715
C037123cadmium sulfatecadmium sulfate results in decreased expression of TP53 mRNA23770381
C028337cadmium telluridecadmium telluride analog results in decreased expression of TP53 mRNA23770381
C040048caffeic acidcaffeic acid affects the expression of TP53 protein11522280
C040048caffeic acidcaffeic acid promotes the reaction [Thapsigargin results in decreased expression of TP53 mRNA]19442820
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester inhibits the reaction [Mustard Compounds results in increased phosphorylation of TP53 protein]17204746
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester inhibits the reaction [Nitrogen Mustard Compounds results in increased phosphorylation of TP53 protein]17204746
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in decreased expression of TP53 protein]22692362
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of TP53 mRNA]20360939
D002110CaffeineCaffeine inhibits the reaction [2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone results in increased phosphorylation of TP53 protein]23523585
D002110Caffeine"Caffeine inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased expression of and results in increased phosphorylation of TP53 protein]"23274516
D002110CaffeineCaffeine inhibits the reaction [Bortezomib results in increased phosphorylation of TP53 protein]12393500
D002110CaffeineCaffeine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]22226932
D002110CaffeineCaffeine inhibits the reaction [Cytarabine results in increased expression of TP53 protein]17977830
D002110CaffeineCaffeine inhibits the reaction [Cytarabine results in increased phosphorylation of TP53 protein]17977830
D002110CaffeineCaffeine inhibits the reaction [decitabine results in increased expression of TP53 protein]17977830
D002110CaffeineCaffeine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
D002110CaffeineCaffeine inhibits the reaction [kaempferol results in increased phosphorylation of TP53 protein]19028473
D002110CaffeineCaffeine inhibits the reaction [Nitric Oxide results in increased phosphorylation of TP53 protein]16024610
D002110CaffeineCaffeine inhibits the reaction [oxaliplatin results in increased expression of TP53 protein modified form]19735649
D002110CaffeineCaffeine inhibits the reaction [silybin results in increased phosphorylation of TP53 protein]16777994
D002110CaffeineCaffeine inhibits the reaction [spermine nitric oxide complex results in increased phosphorylation of TP53 protein]16024610
D002110CaffeineCaffeine results in increased phosphorylation of TP53 protein12811820
D002110CaffeineCaffeine inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 protein]11751435
D002110CaffeineCaffeine inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of TP53 protein]11751435
D000001CalcimycinCalcimycin promotes the reaction [[TP53 protein binds to BAX promoter] which results in increased expression of BAX mRNA]16000378
D000001CalcimycinCalcimycin results in increased expression of TP53 protein16000378
D000001CalcimycinCRYAB protein inhibits the reaction [Calcimycin results in increased expression of TP53 protein]16000378
D000001CalcimycinU 0126 inhibits the reaction [Calcimycin results in increased expression of TP53 protein]16000378
D002118CalciumCalcium results in decreased expression of TP53 protein16043423
D002118CalciumTP53 protein affects the localization of Calcium15059885
C059041calyculin Acalyculin A inhibits the reaction [N-caproylsphingosine affects the splicing of and results in increased expression of TP53 mRNA]25195822
C059041calyculin Acalyculin A inhibits the reaction [N-caproylsphingosine results in increased expression of TP53 protein modified form]25195822
C553149camphorquinonecamphorquinone results in increased phosphorylation of TP53 protein26658076
D002166CamptothecinCamptothecin results in increased expression of TP53 mRNA22560901
D002166Camptothecin3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole promotes the reaction [Camptothecin results in increased expression of TP53 protein]19481069
D002166CamptothecinAcetylcysteine inhibits the reaction [Camptothecin results in increased expression of TP53 protein modified form]17555331
D002166Camptothecin"Camptothecin inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in increased acetylation of TP53 protein]"24726431
D002166CamptothecinCamptothecin results in decreased acetylation of TP53 protein24726431
D002166CamptothecinCamptothecin results in increased expression of TP53 protein12082016|1755533
D002166CamptothecinCamptothecin results in increased glutathionylation of TP53 protein17555331
D002166CamptothecinCamptothecin results in increased phosphorylation of TP53 protein17555331|2665789
D002166CamptothecinCamptothecin results in increased stability of and results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein11741290
D002166Camptothecinnutlin 3 inhibits the reaction [Camptothecin results in increased expression of TP53 protein]24726431
D002166CamptothecinS-ethyl glutathione inhibits the reaction [Camptothecin results in increased expression of TP53 protein modified form]17555331
D002166Camptothecin[SIRT1 mutant form co-treated with Camptothecin] results in increased acetylation of TP53 protein24726431
D002166CamptothecinTP53 mutant form results in decreased susceptibility to Camptothecin24726431
D002166CamptothecinTP53 protein mutant form results in decreased susceptibility to Camptothecin10692111
D002166CamptothecinTP53 protein results in decreased susceptibility to Camptothecin25269479
D002166CamptothecinTP53 protein results in increased susceptibility to Camptothecin23285096|9673414
D002166CamptothecinCamptothecin promotes the reaction [TP53 protein binds to CREBBP protein]13679428
D002166CamptothecinCamptothecin results in increased activity of TP53 protein11279278|1367942
D002166CamptothecinCamptothecin results in increased phosphorylation of TP53 protein13679428
D002166Camptothecinpifithrin inhibits the reaction [Camptothecin promotes the reaction [TP53 protein binds to CREBBP protein]]13679428
D002166Camptothecinpifithrin inhibits the reaction [Camptothecin results in increased activity of TP53 protein]11279278|1367942
D002166CamptothecinCamptothecin results in increased expression of TP53 protein17881359
C081643candesartancandesartan results in increased expression of TP53 mRNA11409658
C081643candesartancandesartan results in increased expression of TP53 protein11409658
C081643candesartancandesartan inhibits the reaction [AGT protein modified form results in increased phosphorylation of TP53 protein]18314486
D002211Capsaicin2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]22226932
D002211Capsaicin2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased expression of TP53 protein]19502594
D002211Capsaicin3-aminobenzamide inhibits the reaction [Capsaicin results in increased expression of TP53 protein]22226932
D002211Capsaicin3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]22226932
D002211CapsaicinAcetylcysteine inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]14871840
D002211Capsaicinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in increased degradation of TP53 protein]19699254
D002211CapsaicinCaffeine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]22226932
D002211CapsaicinCapsaicin promotes the reaction [resveratrol results in increased expression of TP53 protein]19846903
D002211CapsaicinCapsaicin results in decreased degradation of TP53 protein17292493
D002211CapsaicinCapsaicin results in increased degradation of TP53 protein19699254
D002211CapsaicinCapsaicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein17292493
D002211CapsaicinCapsaicin results in increased expression of TP53 mRNA19502594|9461043
D002211CapsaicinCapsaicin results in increased expression of TP53 protein16540674|1899126
D002211CapsaicinCapsaicin results in increased phosphorylation of and results in increased activity of TP53 protein22226932
D002211CapsaicinCapsaicin results in increased phosphorylation of and results in increased expression of TP53 protein19139269|1950259
D002211CapsaicinCapsaicin results in increased phosphorylation of TP53 protein14871840
D002211CapsaicinCAT protein inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]14871840
D002211CapsaicinMAPK8 protein promotes the reaction [Capsaicin results in decreased degradation of TP53 protein]17292493
D002211Capsaicinpifithrin inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]22226932
D002211Capsaicinpyrazolanthrone inhibits the reaction [Capsaicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein]17292493
D002211Capsaicinresveratrol promotes the reaction [Capsaicin results in increased expression of TP53 protein]19846903
D002211CapsaicinTP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]]19846903
D002211CapsaicinTP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]]19846903
D002211CapsaicinTP53 affects the reaction [Capsaicin results in decreased expression of MDM2 protein]19846903
D002211CapsaicinTP53 affects the reaction [Capsaicin results in increased expression of NOS1 protein]19846903
D002211CapsaicinTP53 affects the reaction [Capsaicin results in increased expression of NOS3 protein]19846903
D002211CapsaicinTP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]]19846903
D002211CapsaicinTP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]]19846903
D002211CapsaicinTP53 affects the susceptibility to Capsaicin19846903
D002211CapsaicinTP53 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]17292493
D002211CapsaicinTunicamycin promotes the reaction [Capsaicin results in increased degradation of TP53 protein]19699254
D002219CarbamatesCarbamates analog promotes the reaction [ATM protein results in increased phosphorylation of and results in increased activity of TP53 protein]19376255
D002219CarbamatesCarbamates analog results in increased phosphorylation of and results in increased activity of TP53 protein19376255
D002220CarbamazepineCarbamazepine affects the expression of TP53 mRNA24752500
C006698carbendazimcarbendazim results in increased expression of TP53 mRNA25304545|2605522
D002229CarbenoxoloneCarbenoxolone affects the expression of TP53 mRNA23678415
D002235CarbofuranCarbofuran results in decreased stability of and results in increased degradation of and results in increased mutagenesis of TP53 gene22445671
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of TP53 mRNA17256749
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of TP53 mRNA17522070
C514968carboxymethyl-chitosanbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]26612707
C514968carboxymethyl-chitosancarboxymethyl-chitosan analog promotes the reaction [Curcumin inhibits the reaction [AGT protein modified form results in increased acetylation of TP53 protein]]26612707
C514968carboxymethyl-chitosan[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]26612707
D002330Carmustine[Carmustine co-treated with O(6)-benzylguanine] results in increased expression of TP53 protein15735757
D002330CarmustineCarmustine results in increased expression of TP53 protein15735757|1619338
D002330CarmustineMDM4 protein promotes the reaction [Carmustine results in increased expression of TP53 protein]20472715
D002330CarmustineTP53 protein modified form affects the susceptibility to Carmustine11861384
D002330CarmustineTP53 protein results in decreased susceptibility to Carmustine16193384
D002330CarmustineTP53 results in increased susceptibility to Carmustine10455409
C043211carvedilolcarvedilol affects the expression of TP53 protein22000973
C043211carvedilolcarvedilol inhibits the reaction [Potassium Dichromate results in increased expression of TP53 protein]25245570
D002392CatechinCatechin results in increased expression of TP53 mRNA23706674
D002392CatechinCatechin results in increased expression of TP53 protein23706674
C099555CD 437CD 437 affects the expression of TP5316720286
D002439CefotaximeCefotaxime results in increased expression of TP53 protein15012731
D000068579CelecoxibCelecoxib results in increased activity of and results in increased localization of TP53 protein19706164
D000068579CelecoxibCelecoxib results in increased expression of and results in increased phosphorylation of TP53 protein18760266
D000068579CelecoxibCelecoxib results in increased expression of TP53 mRNA18202791
D000068579CelecoxibCelecoxib results in increased expression of TP53 protein19706164
D000068579Celecoxib[FEC protocol co-treated with Celecoxib] results in decreased expression of TP53 protein16507397
D000068579Celecoxibpifithrin inhibits the reaction [Celecoxib results in increased expression of TP53 protein]19706164
D000068579Celecoxibpifithrin inhibits the reaction [TP53 results in increased susceptibility to Celecoxib]19706164
D000068579CelecoxibTP53 affects the reaction [Celecoxib results in increased expression of CDKN1A mRNA]19706164
D000068579CelecoxibTP53 protein promotes the reaction [Celecoxib results in increased expression of BBC3 protein]18760266
D000068579CelecoxibTP53 results in increased susceptibility to Celecoxib19706164
C532683CellfoodCellfood results in increased expression of TP53 protein24598211
D002512CephalothinCephalothin results in increased expression of TP53 protein15012731
D002518CeramidesCeramides results in increased phosphorylation of TP53 protein23495037
D002518Ceramides[fumonisin B1 results in decreased chemical synthesis of Ceramides] which affects the splicing of and results in decreased expression of TP53 mRNA25195822
D002518Ceramides[fumonisin B1 results in decreased chemical synthesis of Ceramides] which results in decreased phosphorylation of TP53 protein modified form25195822
D002518Ceramides[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [Ceramides results in increased phosphorylation of TP53 protein]23495037
D002518Ceramidesresveratrol promotes the reaction [Ceramides results in increased phosphorylation of TP53 protein]23495037
D002518CeramidesTP53 protein results in increased abundance of Ceramides12967322
D002518Ceramides[UGCG protein results in decreased abundance of Ceramides] which affects the splicing of and results in decreased expression of TP53 mRNA25195822
D002518Ceramides[UGCG protein results in decreased abundance of Ceramides] which results in decreased phosphorylation of TP53 protein25195822
C030583ceric oxideceric oxide results in increased phosphorylation of TP53 protein24987704
C062876cetrorelixcetrorelix results in increased expression of TP53 protein21062912
D002699ChlorambucilChlorambucil results in increased expression of TP538822937
D002699ChlorambucilChlorambucil results in increased expression of TP53 protein18092340
D002699ChlorambucilIL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of TP53]8822937
D002699Chlorambucil[Theophylline co-treated with Chlorambucil] results in increased expression of TP538822937
D002719ChlormethiazoleChlormethiazole inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]16330492
C095932chloro(2,2'-6',2''-terpyridine)(2,2'-bipyridine)ruthenium"chloro(2,2'-6',2''-terpyridine)(2,2'-bipyridine)ruthenium results in increased activity of TP53 protein"19682442
C004656chloroacetaldehydechloroacetaldehyde affects the activity of TP53 protein25596134
D002725ChloroformChloroform results in increased phosphorylation of TP53 protein8076368
D002725ChloroformChloroform results in increased expression of TP53 mRNA17522070
D002725ChloroformChloroform results in increased phosphorylation of TP53 protein8076368
D002734Chlorophyll"Chlorophyll inhibits the reaction [dibenzo(a,l)pyrene results in increased expression of TP53 mRNA]"22079312
C007020chlorophyllinchlorophyllin inhibits the reaction [Cyclophosphamide results in increased mutagenesis of TP53 exon]19227835
C100187chloropicrinchloropicrin results in increased expression of TP53 protein22516760|2454867
D002738ChloroquineChloroquine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
D002738ChloroquineChloroquine results in increased activity of TP5318089834
D002738ChloroquineChloroquine results in increased activity of TP53 protein12082016
D002746ChlorpromazineChlorpromazine affects the activity of TP53 protein25596134
D004390Chlorpyrifosbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chlorpyrifos results in decreased expression of TP53 protein]27993609
D004390ChlorpyrifosChlorpyrifos results in decreased expression of TP53 protein27993609
D004390ChlorpyrifosCycloheximide promotes the reaction [Chlorpyrifos results in decreased expression of TP53 protein]27993609
D004390ChlorpyrifosChlorpyrifos results in increased expression of TP53 mRNA12464398|1745228
D002791Cholesterol, Dietary"Cholesterol, Dietary results in increased expression of TP53 mRNA"27239252
D002791Cholesterol, Dietary"Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of TP53 mRNA]"27239252
D002794CholineCholine results in decreased expression of TP53 mRNA16014740
C034944chromic acidchromic acid results in increased expression of TP53 mRNA27005777
D002857ChromiumCDKN1A affects the reaction [Chromium results in increased expression of TP53 protein]18024214
D002857ChromiumChromium promotes the reaction [TP53 protein binds to BBC3 promoter]18602874
D002857ChromiumChromium promotes the reaction [TP53 protein binds to CDKN1A promoter]18602874
D002857ChromiumChromium results in increased activity of TP53 protein14971653
D002857ChromiumChromium results in increased expression of TP53 protein18024214
D002857ChromiumChromium results in increased stability of and results in increased activity of TP53 protein18602874
D002857ChromiumPRKDC protein promotes the reaction [Chromium results in increased stability of and results in increased activity of TP53 protein]18602874
D002857ChromiumRAS protein promotes the reaction [Chromium results in increased activity of TP53 protein]14971653
D002857ChromiumTP53 mutant form inhibits the reaction [CDKN1A gene mutant form results in increased susceptibility to Chromium]18024214
C074702chromium hexavalent ionbenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [TP53 protein affects the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]]16166740
C074702chromium hexavalent ionchromium hexavalent ion binds to TP53 gene22791815
C074702chromium hexavalent ion[chromium hexavalent ion binds to TP53 gene] which results in increased mutagenesis of TP53 gene22791815
C074702chromium hexavalent ionchromium hexavalent ion results in decreased expression of TP53 protein22666341
C074702chromium hexavalent ion[chromium hexavalent ion results in increased abundance of Reactive Oxygen Species] which results in increased activity of TP53 protein22886373
C074702chromium hexavalent ionchromium hexavalent ion results in increased activity of TP53 protein10574974
C074702chromium hexavalent ionchromium hexavalent ion results in increased expression of TP53 mRNA27793765
C074702chromium hexavalent ionchromium hexavalent ion results in increased expression of TP53 protein10788560|1616674
C074702chromium hexavalent ionchromium hexavalent ion results in increased mutagenesis of TP53 gene22791815
C074702chromium hexavalent ionchromium hexavalent ion results in increased phosphorylation of and results in increased expression of TP53 protein15831465
C074702chromium hexavalent ionpifithrin inhibits the reaction [TP53 protein promotes the reaction [chromium hexavalent ion results in decreased expression of BUB1B protein]]22886373
C074702chromium hexavalent ionTP53 protein affects the reaction [chromium hexavalent ion affects the localization of BAX protein]16166740
C074702chromium hexavalent ionTP53 protein affects the reaction [chromium hexavalent ion affects the localization of DIABLO protein]16166740
C074702chromium hexavalent ionTP53 protein affects the reaction [chromium hexavalent ion results in decreased expression of BCL2L1 protein]16166740
C074702chromium hexavalent ionTP53 protein affects the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]16166740
C074702chromium hexavalent ionTP53 protein affects the reaction [chromium hexavalent ion results in increased expression of BBC3 protein]16166740
C074702chromium hexavalent ionTP53 protein affects the reaction [chromium hexavalent ion results in increased expression of PMAIP1 protein]16166740
C074702chromium hexavalent ionTP53 protein promotes the reaction [chromium hexavalent ion results in decreased expression of BUB1B protein]22886373
C074702chromium hexavalent ionTP53 protein results in increased susceptibility to chromium hexavalent ion10574974|1616674
C043561chrysinchrysin results in increased degradation of TP53 protein14634213
C043561chrysinchrysin results in increased phosphorylation of and affects the localization of TP53 protein25770930
C043561chrysin[Cisplatin co-treated with chrysin] affects the localization of TP53 protein25770930
C043561chrysin[Cisplatin co-treated with chrysin] results in increased phosphorylation of and results in increased expression of TP53 protein25770930
C043561chrysinU 0126 inhibits the reaction [[Cisplatin co-treated with chrysin] affects the localization of TP53 protein]25770930
C043561chrysinU 0126 inhibits the reaction [[Cisplatin co-treated with chrysin] results in increased phosphorylation of TP53 protein]25770930
C043561chrysinchrysin inhibits the reaction [Diethylnitrosamine results in decreased expression of TP53 mRNA]21167192
C043561chrysinchrysin inhibits the reaction [Testosterone results in decreased expression of TP53 mRNA]29247772
C043561chrysin[Diethylnitrosamine co-treated with chrysin] results in increased expression of TP53 protein21167192
C472594chrysophsinchrysophsin promotes the reaction [Epirubicin results in increased expression of TP53 mRNA]26335193
C472594chrysophsinchrysophsin results in increased expression of TP53 mRNA26335193
C472594chrysophsin[Epirubicin analog co-treated with chrysophsin analog] results in increased expression of TP53 mRNA26335193
C472594chrysophsinEpirubicin promotes the reaction [chrysophsin results in increased expression of TP53 mRNA]26335193
C012842Cibacron Blue F 3GACibacron Blue F 3GA results in increased degradation of TP53 protein14634213
C059262cidofovircidofovir affects the activity of TP53 protein25596134
C059262cidofovircidofovir results in increased expression of TP53 protein11697818
C045645cilostazolcilostazol results in increased expression of TP53 protein10642304
C045645cilostazolcilostazol inhibits the reaction [Nitroprusside results in increased phosphorylation of TP53 protein]18311796
C012843cinnamic aldehydecinnamic aldehyde results in decreased expression of TP53 mRNA17178418
C488623cis-bis(3-aminoflavone)dichloroplatinum(II)cis-bis(3-aminoflavone)dichloroplatinum(II) results in increased expression of TP53 mRNA16012788
D002953CitrininCitrinin results in increased expression of TP53 protein20929984
D002953CitrininCitrinin results in increased expression of TP53 protein modified form22564900
C402823CLIK 148CLIK 148 results in increased expression of TP53 protein21484410
D007464Clioquinol2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Clioquinol results in increased phosphorylation of TP53 protein]22627294
D007464ClioquinolClioquinol results in increased phosphorylation of TP53 protein22627294
D004002Clodronic AcidClodronic Acid affects the activity of TP53 protein25596134
C068329clofarabine[resveratrol co-treated with clofarabine] affects the localization of TP53 protein modified form24239893
C068329clofarabine[resveratrol co-treated with clofarabine] results in increased expression of and results in increased activity of TP53 protein modified form24239893
C068329clofarabineTP53 protein affects the susceptibility to [resveratrol co-treated with clofarabine]24239893
D002995Clofibric AcidClofibric Acid affects the expression of TP53 mRNA17602206
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of TP53 mRNA17602206
C055162clopidogrelclopidogrel results in increased expression of TP53 mRNA9447704
C055162clopidogrelclopidogrel results in increased expression of TP53 protein9447704
D003022ClotrimazoleClotrimazole results in increased expression of TP53 protein10223459
D003024ClozapineClozapine results in increased expression of TP53 mRNA16160616
D003024ClozapineCSF3 protein inhibits the reaction [Clozapine results in increased expression of TP53 mRNA]16160616
D003035CobaltCobalt results in increased expression of TP53 mRNA22983774
D003035CobaltCobalt results in increased expression of and results in increased phosphorylation of TP53 protein24068677
D003035CobaltCobalt results in increased expression of and results in increased stability of TP53 protein23052192
D003035CobaltCobalt results in increased expression of TP53 protein21598295
D003035CobaltTP53 protein affects the reaction [Cobalt results in increased expression of BBC3 mRNA]24068677
D003035CobaltTP53 protein affects the reaction [Cobalt results in increased expression of CDKN1A mRNA]24068677
D003035CobaltTP53 protein affects the reaction [Cobalt results in increased expression of MDM2 mRNA]24068677
D003035CobaltTP53 protein affects the reaction [Cobalt results in increased expression of PMAIP1 mRNA]24068677
D003035Cobalt[tungsten carbide co-treated with Cobalt] results in increased expression of and results in increased stability of TP53 protein23052192
C007095cobaltiprotoporphyrin"[1,8-diazafluoren-one results in decreased activity of HMOX1 protein] inhibits the reaction [cobaltiprotoporphyrin results in increased expression of TP53 protein]"18042465
C007095cobaltiprotoporphyrincobaltiprotoporphyrin affects the expression of TP53 protein24211270
C007095cobaltiprotoporphyrincobaltiprotoporphyrin results in increased expression of TP53 protein18042465
C007095cobaltiprotoporphyrin[zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [cobaltiprotoporphyrin results in increased expression of TP53 protein]18042465
C007095cobaltiprotoporphyrincobaltiprotoporphyrin results in decreased expression of TP53 protein20357190
C007095cobaltiprotoporphyrinzinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in decreased expression of TP53 protein]20357190
C018021cobaltous chloride[3-methyladenine co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein23380477
C018021cobaltous chloride3-methyladenine inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein]23380477
C018021cobaltous chlorideAcetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of and results in increased activity of TP53 protein]10951577
C018021cobaltous chloride[bafilomycin A1 co-treated with cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein23380477
C018021cobaltous chloridebafilomycin A1 inhibits the reaction [[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein]23380477
C018021cobaltous chloride[cobaltous chloride co-treated with TP53 gene mutant form] results in decreased expression of and results in decreased phosphorylation of TP53 protein21687937|2168793
C018021cobaltous chloride[cobaltous chloride co-treated with TP53 gene mutant form] results in decreased expression of BBC3 protein21687937
C018021cobaltous chloride[cobaltous chloride co-treated with TP53 gene mutant form] results in decreased expression of TP53 protein23380477|2338047
C018021cobaltous chloride[cobaltous chloride co-treated with TP53 gene mutant form] results in decreased expression of TP53 protein modified form23380477|2338047
C018021cobaltous chloride[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CASP3 protein21687937
C018021cobaltous chloride[cobaltous chloride co-treated with TP53 gene mutant form] results in increased activity of CTSB protein21687937|2338047
C018021cobaltous chloride[cobaltous chloride co-treated with TP53 gene mutant form] results in increased expression of ATG12 protein23380477
C018021cobaltous chloride[cobaltous chloride co-treated with TP53 gene mutant form] results in increased expression of BECN1 protein23380477
C018021cobaltous chloride[cobaltous chloride co-treated with TP53 gene mutant form] results in increased expression of CDKN1A protein21687937
C018021cobaltous chloridecobaltous chloride inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]19714248
C018021cobaltous chloridecobaltous chloride inhibits the reaction [[Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BAX mRNA]19714248
C018021cobaltous chloridecobaltous chloride inhibits the reaction [[Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3 mRNA]19714248
C018021cobaltous chloridecobaltous chloride inhibits the reaction [HIPK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]19714248
C018021cobaltous chloridecobaltous chloride results in decreased activity of TP53 protein25446071
C018021cobaltous chloride[cobaltous chloride results in decreased activity of TP53 protein] inhibits the reaction [TP53 protein binds to TP53 gene]25446071|2544607
C018021cobaltous chloride[cobaltous chloride results in decreased activity of TP63 protein] inhibits the reaction [TP63 protein binds to TP53 gene]25446071
C018021cobaltous chloride[cobaltous chloride results in decreased activity of TP73 protein] inhibits the reaction [TP73 protein binds to TP53 gene]25446071
C018021cobaltous chloridecobaltous chloride results in increased expression of and results in increased activity of TP53 protein10951577
C018021cobaltous chloridecobaltous chloride results in increased expression of and results in increased phosphorylation of TP53 protein21687937
C018021cobaltous chloridecobaltous chloride results in increased expression of TP53 mRNA22269387
C018021cobaltous chloridecobaltous chloride results in increased expression of TP53 protein20974702|2338047
C018021cobaltous chlorideDitiocarb inhibits the reaction [cobaltous chloride results in increased expression of and results in increased activity of TP53 protein]10951577
C018021cobaltous chlorideMDM2 protein promotes the reaction [cobaltous chloride inhibits the reaction [HIPK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]]19714248
C018021cobaltous chloridepeoniflorin inhibits the reaction [cobaltous chloride results in increased expression of TP53 mRNA]22269387
C018021cobaltous chloride[pifithrin co-treated with cobaltous chloride] results in increased expression of and affects the localization of TP53 protein23380477
C018021cobaltous chlorideTP53 gene mutant form promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]16527254
C018021cobaltous chloride[TP53 protein co-treated with cobaltous chloride] affects the localization of AIFM1 protein21687937
C018021cobaltous chlorideTP53 protein promotes the reaction [cobaltous chloride results in increased activity of CASP3 protein]21687937
C018021cobaltous chlorideTP53 protein promotes the reaction [cobaltous chloride results in increased activity of CASP9 protein]23380477
C018021cobaltous chloridezinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]19714248
C018021cobaltous chloridecobaltous chloride promotes the reaction [Diethylnitrosamine results in increased expression of TP53 protein]11751435
D009243NAD[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene10334203
D009243NADbathocuproine inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
D009243NADCAT protein inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
D009243NADNAD results in decreased expression of TP53 protein12390773
D009249NADPNADP promotes the reaction [sodium bichromate results in increased expression of TP53 protein]10942736
D003078ColchicineTP53 protein affects the reaction [Colchicine results in increased phosphorylation of JUN protein]12221076
D003078ColchicineTP53 protein affects the reaction [Colchicine results in increased phosphorylation of MAPK8 protein]12221076
D003078ColchicineTP53 protein affects the reaction [Colchicine results in increased phosphorylation of MAPK9 protein]12221076
D005576ColforsinColforsin results in increased expression of TP53 protein10642304
D003091ColistinAnisomycin promotes the reaction [Colistin results in increased expression of TP53 protein]28842171
D003091ColistinColistin results in increased expression of TP53 protein28842171
D003091Colistinpyrazolanthrone inhibits the reaction [Colistin results in increased expression of TP53 protein]28842171
D003300Copper[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene10334203
D003300Copperbathocuproine inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
D003300Copperbathocuproine inhibits the reaction [[phenylhydroquinone co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
D003300Copperbathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein]11964141
D003300CopperCAT protein inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
D003300CopperCAT protein inhibits the reaction [[phenylhydroquinone co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
D003300Copper[Copper binds to Isatin binds to 2-(2-aminoethyl)pyridine] which results in increased expression of TP53 protein17327230
D003300Copper[Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of TP53 protein17327230
D003300CopperCopper results in decreased activity of TP53 protein16246896
D003300Copper[Copper results in increased activity of TP53 protein] which results in increased expression of CDKN1A mRNA16391388
D003300Copper[Copper results in increased activity of TP53 protein] which results in increased expression of CDKN2A mRNA16391388
D003300Copper[Copper results in increased activity of TP53 protein] which results in increased expression of EI24 mRNA16391388
D003300Copper[Copper results in increased activity of TP53 protein] which results in increased expression of ENC1 mRNA16391388
D003300Copper[Copper results in increased activity of TP53 protein] which results in increased expression of IGFBP6 mRNA16391388
D003300Copper[Copper results in increased activity of TP53 protein] which results in increased expression of PTGES mRNA16391388
D003300Copper[Copper results in increased activity of TP53 protein] which results in increased expression of RPRM mRNA16391388
D003300CopperCopper results in increased expression of and affects the localization of TP53 protein16391388
D003300CopperCopper results in increased expression of TP53 protein15880691|2087583
D003300CopperCopper results in increased oxidation of TP53 protein11964141
D003300Copper[N-hydroxy-4-aminobiphenyl co-treated with Copper] results in increased mutagenesis of TP53 gene11275476
D003300Copper[phenylhydroquinone co-treated with Copper] results in increased mutagenesis of TP53 gene10334203
D003300Copper[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein11964141
D003300Copper[Thiosemicarbazones binds to Copper] which results in decreased activity of TP53 protein20931265
D003300CopperTP53 protein inhibits the reaction [Copper results in increased phosphorylation of MAPK1 protein]15880691
D003300CopperTP53 protein inhibits the reaction [Copper results in increased phosphorylation of MAPK3 protein]15880691
D003300CopperTP53 protein promotes the reaction [Copper results in increased abundance of Reactive Oxygen Species]15880691
D003300CopperTP53 protein results in increased susceptibility to Copper15880691
D003300CopperTretinoin inhibits the reaction [[Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of TP53 protein]17327230
D003300Copper[Copper deficiency co-treated with tetrathiomolybdate] results in increased expression of TP53 protein22276220
D003300Copper"[Copper co-treated with 1,2-diphenylhydrazine] results in increased mutagenesis of TP53 gene"10798712
D003300Copper"piperidine promotes the reaction [[Copper co-treated with 1,2-diphenylhydrazine] results in increased mutagenesis of TP53 gene]"10798712
C464760copper-1,10-phenanthroline"copper-1,10-phenanthroline results in increased expression of TP53 protein"24638265
D019327Copper SulfateCopper Sulfate results in decreased expression of TP53 mRNA27825931
D019327Copper SulfateCopper Sulfate results in increased phosphorylation of and results in increased expression of TP53 protein15001399
C058120cordycepincordycepin results in increased expression of TP53 mRNA28987792
C058120cordycepinADORA2A mutant form inhibits the reaction [cordycepin results in increased phosphorylation of and results in increased expression of TP53 protein]24704558
C058120cordycepincordycepin promotes the reaction [Etoposide results in increased expression of TP53 protein]23690541
C058120cordycepincordycepin results in increased phosphorylation of and results in increased expression of TP53 protein24704558
C058120cordycepinTP53 mutant form inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]24704558
C058120cordycepinTP53 mutant form inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]24704558
C058120cordycepinZM 241385 inhibits the reaction [cordycepin results in increased phosphorylation of and results in increased expression of TP53 protein]24704558
C030123coumarincoumarin results in increased expression of TP53 mRNA26946349
C402665CP 31398CP 31398 results in increased activity of TP53 protein15155752|1617756
C402665CP 31398CP 31398 results in increased expression of and results in increased activity of TP53 protein mutant form21109480
C539572CpG-ODN DSP30[CpG-ODN DSP30 co-treated with IL2 protein] results in increased expression of TP53 protein27634759
C408982CPG-oligonucleotideCPG-oligonucleotide results in decreased expression of TP53 mRNA21878529
C024015cryptolepinecryptolepine results in increased activity of TP53 protein16120219
C024015cryptolepinecryptolepine results in increased expression of TP53 protein16120219
C542041cudraflavone Bcudraflavone B results in increased expression of TP53 protein23881456
C542041cudraflavone Bresveratrol inhibits the reaction [cudraflavone B results in increased expression of TP53 protein]23881456
C542041cudraflavone Bsirtinol promotes the reaction [cudraflavone B results in increased expression of TP53 protein]23881456
C030973cupric oxidecupric oxide analog results in decreased phosphorylation of and results in decreased expression of TP53 protein25336953
C030973cupric oxidecupric oxide results in decreased expression of TP53 mRNA22077320
D003471CuprizoneCuprizone results in increased expression of TP53 mRNA26577399|2752363
D003474Curcumin"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Curcumin results in increased phosphorylation of TP53 protein]"19020741
D003474Curcumin[arsenic trioxide co-treated with Curcumin] results in increased expression of TP53 protein27430728
D003474CurcuminCurcumin affects the expression of TP53 protein24211270
D003474CurcuminCurcumin affects the localization of TP53 protein17332930
D003474CurcuminCurcumin analog affects the expression of TP53 mRNA17041101
D003474CurcuminCurcumin analog affects the expression of TP53 protein17041101
D003474CurcuminCurcumin analog results in decreased expression of TP53 mRNA26409325
D003474Curcumin[Curcumin co-treated with Metribolone] results in increased phosphorylation of TP53 protein21134073
D003474CurcuminCurcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased activity of TP53 protein]24664296
D003474CurcuminCurcumin inhibits the reaction [bisphenol A results in decreased expression of TP53 protein]23222814
D003474CurcuminCurcumin inhibits the reaction [bisphenol A results in increased expression of TP53 protein]24831732
D003474CurcuminCurcumin results in increased acetylation of TP53 protein17332930
D003474Curcumin[Curcumin results in increased expression of SERPINB5] which results in increased expression of TP53 protein19944674
D003474CurcuminCurcumin results in increased expression of TP5325644192
D003474CurcuminCurcumin results in increased expression of TP53 protein23222814|2525640
D003474CurcuminCurcumin results in increased phosphorylation of TP53 protein17332930|1902074
D003474CurcuminSB 203580 inhibits the reaction [Curcumin results in increased phosphorylation of TP53 protein]19020741
D003474CurcuminCurcumin results in decreased expression of TP53 protein22714040
D003474Curcuminbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]26612707
D003474Curcumincarboxymethyl-chitosan analog promotes the reaction [Curcumin inhibits the reaction [AGT protein modified form results in increased acetylation of TP53 protein]]26612707
D003474Curcumin[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]26612707
D003474CurcuminCurcumin inhibits the reaction [AGT protein modified form promotes the reaction [TP53 protein binds to EP300 protein]]26612707
D003474CurcuminCurcumin inhibits the reaction [AGT protein modified form results in increased expression of and results in increased phosphorylation of and results in increased acetylation of TP53 protein]26612707
D003474CurcuminCurcumin inhibits the reaction [Cyclophosphamide results in increased mutagenesis of TP53 exon]19227835
D003474CurcuminCurcumin inhibits the reaction [TP53 protein binds to EP300 protein]26612707
D003474CurcuminCurcumin results in decreased expression of and results in decreased acetylation of TP53 protein26612707
D003474CurcuminCurcumin results in increased expression of TP5318462866
D003484Cyanamide[Ethanol co-treated with Cyanamide] results in increased expression of TP53 mRNA12003908
C057862cyanoginosin LRcyanoginosin LR results in increased expression of TP5316624733
C057862cyanoginosin LRcyanoginosin LR results in increased expression of TP53 protein18214937|2042119
C057862cyanoginosin LRcyanoginosin LR results in increased phosphorylation of TP53 protein20421190
C057862cyanoginosin LR[cyanoginosin LR co-treated with Buthionine Sulfoximine] results in increased expression of TP53 protein25410294
D003513CycloheximideCycloheximide inhibits the reaction [Fluorouracil results in increased expression of TP53 protein]15016801
D003513CycloheximideCycloheximide promotes the reaction [Chlorpyrifos results in decreased expression of TP53 protein]27993609
D003513CycloheximideCycloheximide results in decreased expression of TP53 protein20943951
D003513CycloheximideTP53 mutant form results in increased susceptibility to Cycloheximide21875941
D003513CycloheximideCycloheximide inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein]9790906
D003520CyclophosphamideCyclophosphamide metabolite results in increased activity of TP53 protein20655369|2201021
D003520CyclophosphamideCyclophosphamide results in increased mutagenesis of TP53 exon9610789
D003520CyclophosphamideTP53 protein affects the susceptibility to Cyclophosphamide15182437
D003520CyclophosphamideTP53 protein promotes the reaction [Methotrexate results in increased susceptibility to Cyclophosphamide metabolite]22010212
D003520Cyclophosphamideastaxanthine inhibits the reaction [Cyclophosphamide results in increased expression of TP53 protein]20038455
D003520Cyclophosphamidechlorophyllin inhibits the reaction [Cyclophosphamide results in increased mutagenesis of TP53 exon]19227835
D003520CyclophosphamideCurcumin inhibits the reaction [Cyclophosphamide results in increased mutagenesis of TP53 exon]19227835
D003520CyclophosphamideCyclophosphamide results in increased expression of TP53 protein20038455
D003520CyclophosphamideCyclophosphamide results in increased mutagenesis of TP53 exon19227835
D016572CyclosporineCyclosporine affects the activity of TP53 protein25596134
D016572Cyclosporine[Cyclosporine co-treated with NGF protein] results in increased expression of TP53 mRNA24244623
D016572CyclosporineCyclosporine inhibits the reaction [Reactive Oxygen Species affects the localization of TP53 protein]26884717
D016572CyclosporineCyclosporine results in increased expression of TP53 mRNA20106945
D016572CyclosporineCyclosporine affects the activity of TP53 protein25596134
D016572CyclosporineCyclosporine affects the expression of TP53 protein24971338
D016572CyclosporineCyclosporine results in increased expression of TP5325299210
D016572CyclosporineCyclosporine results in increased expression of TP53 mRNA24971338
C017160cypermethrincypermethrin results in increased expression of TP53 mRNA20965546|2131646
C017160cypermethrincypermethrin results in decreased expression of TP53 mRNA27704156
C017160cypermethrincypermethrin results in increased expression of TP53 mRNA22528246|2475904
C017160cypermethrincypermethrin results in increased expression of TP53 protein22528246
C017160cypermethrinVitamin E inhibits the reaction [cypermethrin results in increased expression of TP53 mRNA]24759048
D003561CytarabineCaffeine inhibits the reaction [Cytarabine results in increased expression of TP53 protein]17977830
D003561CytarabineCaffeine inhibits the reaction [Cytarabine results in increased phosphorylation of TP53 protein]17977830
D003561CytarabineCytarabine results in increased activity of TP53 protein22010212
D003561CytarabineCytarabine results in increased expression of TP53 protein10200513|1208201
D003561Cytarabine[Cytarabine results in increased expression of TP53 protein] which results in increased expression of BAX protein10200513
D003561CytarabineCytarabine results in increased phosphorylation of TP53 protein10200513|1797783
D003561Cytarabine[fludarabine co-treated with Cytarabine co-treated with docetaxel] results in increased expression of TP53 protein9703875
D003561CytarabineTP53 gene mutant form results in increased susceptibility to Cytarabine24675086
D003561CytarabineCytarabine results in increased expression of TP53 protein14766721|1520318
D003561CytarabineCytarabine results in increased expression of TP53 protein12781215
D003571Cytochalasin BCytochalasin B results in increased expression of TP53 protein27640744
C015773dabequindabequin results in increased activity of TP53 protein12082016
D003609DactinomycinCadmium Chloride inhibits the reaction [Dactinomycin results in increased expression of and results in increased activity of TP53 protein]10531375
D003609DactinomycinCadmium inhibits the reaction [Dactinomycin results in increased expression of and results in increased activity of TP53 protein]10531375
D003609DactinomycinDactinomycin promotes the reaction [MRPL41 protein results in increased stability of and affects the localization of TP53 protein]16024796
D003609DactinomycinDactinomycin results in increased activity of TP53 protein12869419|2065536
D003609DactinomycinDactinomycin results in increased expression of and affects the localization of TP53 protein12807743
D003609DactinomycinDactinomycin results in increased expression of and results in increased activity of TP53 protein10531375
D003609DactinomycinDactinomycin results in increased expression of TP53 protein17581298
D003609DactinomycinDactinomycin results in increased expression of TP53 protein modified form12927789
D003609DactinomycinMorphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]12927789
D003609DactinomycinNaloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]]12927789
C004742daidzeindaidzein results in increased expression of TP53 protein19800779
D003630Daunorubicin[Daunorubicin co-treated with Magnetite Nanoparticles] results in increased activity of TP53 protein21518493
D003630DaunorubicinDaunorubicin results in increased activity of TP53 protein12112851
D003630DaunorubicinDaunorubicin results in increased expression of TP53 mRNA12656675
D003630DaunorubicinDaunorubicin results in increased phosphorylation of and results in increased expression of TP53 protein23872705
D003634DDTDDT results in decreased expression of TP53 mRNA25410620
D003634DDTDDT results in decreased expression of TP53 protein25410620
D003634DDTDDT results in increased methylation of TP53 promoter25410620
C017180decamethrindecamethrin results in increased expression of TP53 mRNA25439240|2601367
C017180decamethrindecamethrin results in increased expression of TP53 protein10771154|2601367
C017180decamethrinoleuropein inhibits the reaction [decamethrin results in increased expression of TP53 protein]28595958
C017180decamethrinPlant Extracts inhibits the reaction [decamethrin results in increased expression of TP53 protein]28595958
C017180decamethrinTea inhibits the reaction [decamethrin results in increased expression of TP53 mRNA]26013673
C017180decamethrinTea inhibits the reaction [decamethrin results in increased expression of TP53 protein]26013673
C017180decamethrinVitamin E inhibits the reaction [decamethrin results in increased expression of TP53 mRNA]25439240
C014347decitabineATR protein affects the reaction [decitabine results in increased expression of TP53 protein]17977830
C014347decitabineCaffeine inhibits the reaction [decitabine results in increased expression of TP53 protein]17977830
C014347decitabinedecitabine affects the localization of TP53 protein19037090
C014347decitabinedecitabine affects the localization of TP53 protein modified form17991895
C014347decitabine[decitabine affects the methylation of BAX gene] affects the reaction [TP53 protein results in increased expression of BAX mRNA]18608210
C014347decitabine[decitabine affects the methylation of PMAIP1 gene] affects the reaction [TP53 protein results in increased expression of PMAIP1 mRNA]18608210
C014347decitabine[decitabine affects the methylation of TP53AIP1 gene] affects the reaction [TP53 protein results in increased expression of TP53AIP1 mRNA]18608210
C014347decitabine[decitabine affects the methylation of TP53I3 gene] affects the reaction [TP53 protein results in increased expression of TP53I3 mRNA]18608210
C014347decitabine[decitabine co-treated with TP53 protein] results in increased expression of RAB6C mRNA18992151
C014347decitabinedecitabine promotes the reaction [ATR protein results in increased phosphorylation of TP53 protein]17977830
C014347decitabinedecitabine promotes the reaction [EP300 protein binds to TP53 protein]17977830
C014347decitabinedecitabine promotes the reaction [KAT2B protein binds to TP53 protein]17977830
C014347decitabine[decitabine promotes the reaction [TP53 protein binds to CDKN1A promoter]] which results in increased expression of CDKN1A protein14722112
C014347decitabinedecitabine promotes the reaction [TP53 protein binds to FPR1 promoter]19037090
C014347decitabinedecitabine promotes the reaction [TP53 protein binds to RAB6C protein]18992151
C014347decitabinedecitabine promotes the reaction [TP53 protein modified form binds to CDKN1A promoter]17977830
C014347decitabinedecitabine results in decreased methylation of TP53 promoter19037090
C014347decitabinedecitabine results in decreased ubiquitination of TP53 protein17977830
C014347decitabinedecitabine results in increased acetylation of TP53 protein17977830
C014347decitabine[decitabine results in increased expression of and affects the localization of CDKN1A protein] which results in increased activity of TP53 protein17389721
C014347decitabinedecitabine results in increased expression of and results in increased localization of and results in increased activity of TP53 protein17389721
C014347decitabinedecitabine results in increased expression of and results in increased stability of TP53 protein23300844
C014347decitabinedecitabine results in increased expression of TP53 mRNA16025287|1778557
C014347decitabinedecitabine results in increased expression of TP53 protein15753979|1602528
C014347decitabinedecitabine results in increased phosphorylation of TP53 protein18636160|1973295
C014347decitabine[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of TP53 protein22534328
C014347decitabineTP53 affects the reaction [decitabine results in increased expression of CDKN1A protein]14722112
C014347decitabineTP53 gene mutant form inhibits the reaction [decitabine results in increased expression of CDKN1A protein]14722112
C014347decitabineTP53 protein affects the reaction [decitabine affects the expression of APAF1 mRNA]17133271
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of ABHD18 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of ALDH6A1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of AMH mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of BAG2 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of BIRC5 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of BIRC5 protein]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of BSN mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of C3ORF62 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of CAPN5 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of CCDC18 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of CCNF mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of CDC25C mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of CENPF mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of CEP57 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of CNTRL mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of ENOX1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of FAM29A mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of FZD7 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of GLI2 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of GPR162 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of HMGB1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of LMNB1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of LZTFL1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of MET mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of MSI1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of MYO18A mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of NEDD4L mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of NEK2 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of NFIX mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of NR2F1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of NRTN mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of NUMA1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of NXPH4 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of OLA1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of PABPC3 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of PTPN9 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of RAPGEFL1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of REEP3 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of RPSA mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of RTN3 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of SAMD5 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of SH3RF2 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of SUN2 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of TBC1D17 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of TMEM18 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of TNKS1BP1 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in decreased expression of ZC3H3 mRNA]19363521
C014347decitabineTP53 protein affects the reaction [decitabine results in increased expression of CDKN1A protein]18223691
C014347decitabineTP53 protein affects the reaction [decitabine results in increased expression of RRM2B mRNA]19010910
C014347decitabineTP53 protein modified form affects the reaction [decitabine results in increased expression of CDKN1A protein]17977830
C014347decitabineTP53 protein promotes the reaction [decitabine results in increased expression of CDKN1A protein]15753979
C014347decitabinedecitabine results in decreased methylation of TP53 promoter21449042
C014347decitabinedecitabine results in increased expression of TP53 mRNA21449042
D003671DEET[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TP53 protein12587291
D003676Deferoxamine"Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]"16357363
D003676DeferoxamineDeferoxamine inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]10942736
D003676DeferoxamineDeferoxamine results in increased expression of TP53 protein23483119
D003676DeferoxamineTP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254
D003676DeferoxamineTP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of PTGS2 protein]16527254
D003676DeferoxamineTP53 protein results in decreased susceptibility to Deferoxamine16527254
C107676deguelin[deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of TP53 protein25242579
C107676deguelindeguelin results in decreased expression of TP53 mRNA22227970
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased expression of TP53 mRNA15752352
D013759DronabinolCNR1 affects the reaction [Dronabinol results in decreased sumoylation of TP53 protein]19819240
D013759DronabinolDronabinol results in decreased sumoylation of TP53 protein19819240
C576677demycarosyl-3D-digitoxosylmithramycin SKdemycarosyl-3D-digitoxosylmithramycin SK results in increased expression of TP53 mRNA26079942
C576677demycarosyl-3D-digitoxosylmithramycin SK[Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in increased expression of TP53 mRNA26079942
C576677demycarosyl-3D-digitoxosylmithramycin SKDeoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in increased expression of TP53 mRNA]26079942
D003840Deoxycholic AcidDeoxycholic Acid results in increased expression of TP53 mRNA20137712
D003840Deoxycholic AcidTP53 protein affects the reaction [[Deoxycholic Acid results in increased expression of CCND1 protein] which affects the localization of BAX protein]17431217
D003840Deoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in increased expression of TP53 mRNA]20137712
D003847Deoxyglucose[Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in increased expression of TP53 mRNA26079942
D003847DeoxyglucoseDeoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in increased expression of TP53 mRNA]26079942
D003847DeoxyglucoseTP53 protein inhibits the reaction [Deoxyglucose results in decreased abundance of Adenosine Triphosphate]21042727
C007262deoxynivalenoldeoxynivalenol results in increased activity of TP53 protein19664677
C007262deoxynivalenol[pifithrin results in decreased activity of TP53 protein] which results in decreased susceptibility to deoxynivalenol22491426
C007262deoxynivalenolAcetylcysteine promotes the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]29109043
C007262deoxynivalenol[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA29109043
C007262deoxynivalenoldeoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]29109043
C007262deoxynivalenolfumonisin B1 inhibits the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]29109043
C007262deoxynivalenolZearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA]29109043
D003868DequaliniumDequalinium results in increased expression of TP53 protein21548882
D064791Desoxycorticosterone Acetate"[Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression of TP53 mRNA"22228705
D003907DexamethasoneDexamethasone inhibits the reaction [TP53 protein binds to FPR1 promoter]19037090
D003907DexamethasoneDexamethasone results in decreased expression of TP53 protein19037090
D003907DexamethasoneDexamethasone results in increased activity of TP53 protein22010212
D003907DexamethasoneDexamethasone results in decreased expression of TP53 mRNA17522070
C100261diacetyldiphenylurea bisguanylhydrazone"diacetyldiphenylurea bisguanylhydrazone inhibits the reaction [5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in increased expression of TP53 protein modified form]"23470866
C028009diallyl disulfideAcetylcysteine inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]19202565
C028009diallyl disulfidediallyl disulfide results in increased expression of TP53 protein11925476|1920256
C028009diallyl disulfideGlutathione inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]19202565
C028009diallyl disulfideTP53 protein affects the reaction [diallyl disulfide results in increased expression of GDF15 protein]11925476
C042577diallyl trisulfidediallyl trisulfide affects the localization of TP53 protein24415872
C042577diallyl trisulfidediallyl trisulfide results in increased expression of and affects the localization of TP53 protein19823037
C042577diallyl trisulfidediallyl trisulfide results in increased expression of TP53 mRNA19823037|2441587
C042577diallyl trisulfidediallyl trisulfide results in increased expression of TP53 protein23754639|2857177
D003958DiamideDiamide results in increased glutathionylation of TP53 protein17555331
D016190CarboplatinCarboplatin results in increased expression of TP53 protein15131059|9664115
D003974Diatrizoate MeglumineDiatrizoate Meglumine results in increased expression of TP53 mRNA28412091
D003974Diatrizoate MeglumineLansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of TP53 mRNA]28412091
D003976DiazinonDiazinon results in increased expression of TP53 mRNA27920530
D003976DiazinonMagnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of TP53 mRNA]27920530
D003976Diazinon[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of TP53 mRNA]27920530
D003976DiazinonDiazinon affects the expression of TP53 mRNA22546817
D003976DiazinonDiazinon results in increased expression of TP53 mRNA17452286
D003981DiazoxideDiazoxide results in decreased expression of TP53 mRNA16426753
C041516dibenzo(a,e)pyrene"dibenzo(a,e)pyrene results in increased phosphorylation of TP53 protein"17961608
C041517dibenzo(a,l)pyrene"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein]"24954032
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein"24954032
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased expression of TP53 protein"15548639
C041517dibenzo(a,l)pyrene"Estradiol promotes the reaction [dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein]"24954032
C041517dibenzo(a,l)pyrene"Tetrachlorodibenzodioxin promotes the reaction [dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein]"24954032
C041517dibenzo(a,l)pyrene"TP53 protein affects the reaction [dibenzo(a,l)pyrene results in increased expression of CYP1A1 protein]"25398514
C041517dibenzo(a,l)pyrene"TP53 protein results in increased susceptibility to dibenzo(a,l)pyrene"25398514
C041517dibenzo(a,l)pyrene"Chlorophyll inhibits the reaction [dibenzo(a,l)pyrene results in increased expression of TP53 mRNA]"22079312
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased expression of TP53 mRNA"22079312
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein"16005925|1796160
C041517dibenzo(a,l)pyrene"pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein]"16005925
C041517dibenzo(a,l)pyrene"SB 203580 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein]"16005925
C041517dibenzo(a,l)pyrene"U 0126 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein]"16005925
D000072338Dibenzofurans, Polychlorinated"[Polychlorinated Dibenzodioxins co-treated with Dibenzofurans, Polychlorinated] results in increased expression of TP53 mRNA"17850846
D015946Ethylene DibromideEthylene Dibromide results in increased mutagenesis of TP53 gene14715658
D003994Bucladesine[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of TP53 protein22534328
D003994Bucladesine[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of TP53 protein22534328
D002945Cisplatin"2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one promotes the reaction [Cisplatin results in increased localization of TP53 protein mutant form]"21109480
D002945CisplatinAcetylcysteine inhibits the reaction [Cisplatin results in increased expression of TP53]15496615
D002945CisplatinAcetylcysteine inhibits the reaction [Cisplatin results in increased glutathionylation of TP53 protein]17555331
D002945CisplatinAscorbic Acid promotes the reaction [Cisplatin results in increased expression of TP53 protein]21429301
D002945Cisplatin[ATR co-treated with TP53] results in decreased susceptibility to Cisplatin21258400
D002945CisplatinBRCA1 mutant form promotes the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased activity of and results in increased phosphorylation of CHEK1 protein]]]21875941
D002945CisplatinBRCA1 mutant form promotes the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of H2AFX protein]]]21875941
D002945CisplatinBRCA1 mutant form promotes the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form results in increased susceptibility to Cisplatin]]21875941
D002945CisplatinCHEK1 mutant form promotes the reaction [TP53 mutant form results in increased susceptibility to Cisplatin]21875941
D002945CisplatinCisplatin affects the activity of TP53 protein25596134
D002945CisplatinCisplatin affects the localization of TP53 protein21858171
D002945Cisplatin[Cisplatin co-treated with chrysin] affects the localization of TP53 protein25770930
D002945Cisplatin[Cisplatin co-treated with chrysin] results in increased phosphorylation of and results in increased expression of TP53 protein25770930
D002945Cisplatin[Cisplatin co-treated with fisetin] affects the localization of TP53 protein21216935
D002945Cisplatin[Cisplatin co-treated with fisetin] results in increased expression of TP53 protein21216935
D002945Cisplatin[Cisplatin co-treated with fisetin] results in increased phosphorylation of TP53 protein21216935
D002945Cisplatin[Cisplatin co-treated with Quercetin] results in decreased expression of TP53 mRNA27514524
D002945CisplatinCisplatin inhibits the reaction [TP53 protein results in increased expression of CDKN1A protein]19548002
D002945CisplatinCisplatin promotes the reaction [TP53 protein binds to MDM2 promoter]21552291
D002945CisplatinCisplatin promotes the reaction [TP53 protein binds to STK17A promoter]21489989
D002945CisplatinCisplatin promotes the reaction [TP53 protein results in increased expression of BAX]21552291
D002945CisplatinCisplatin promotes the reaction [TP53 protein results in increased expression of BBC3 mRNA]21532991
D002945CisplatinCisplatin promotes the reaction [TP53 protein results in increased expression of CDKN1A mRNA]21489989
D002945CisplatinCisplatin promotes the reaction [TP53 protein results in increased expression of FAS mRNA]21532991
D002945CisplatinCisplatin promotes the reaction [TP53 protein results in increased expression of MDM2]21552291
D002945CisplatinCisplatin promotes the reaction [TP53 protein results in increased expression of PMAIP1 mRNA]21532991
D002945CisplatinCisplatin promotes the reaction [TP53 protein results in increased expression of STK17A mRNA]21489989
D002945CisplatinCisplatin results in decreased phosphorylation of TP53 protein15854392
D002945CisplatinCisplatin results in increased acetylation of TP53 protein21532991
D002945CisplatinCisplatin results in increased expression of and affects the localization of TP53 protein12807743
D002945CisplatinCisplatin results in increased expression of and results in increased acetylation of TP53 protein21660965
D002945CisplatinCisplatin results in increased expression of TP5315496615|2155229
D002945CisplatinCisplatin results in increased expression of TP53 mRNA15454482|2087807
D002945CisplatinCisplatin results in increased expression of TP53 protein12082016|1599022
D002945CisplatinCisplatin results in increased expression of TP53 protein modified form21274007
D002945CisplatinCisplatin results in increased glutathionylation of TP53 protein17555331
D002945CisplatinCisplatin results in increased localization of TP53 protein21109480
D002945CisplatinCisplatin results in increased localization of TP53 protein mutant form21109480
D002945CisplatinCisplatin results in increased phosphorylation of and results in increased expression of TP53 protein24799992
D002945CisplatinCisplatin results in increased phosphorylation of TP53 protein20145152|2128535
D002945CisplatinCisplatin results in increased stability of and results in increased activity of TP53 protein14562046
D002945CisplatinCITED2 mutant form promotes the reaction [Cisplatin results in increased expression of and results in increased acetylation of TP53 protein]21660965
D002945CisplatinCITED2 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of TP53 protein]21660965
D002945Cisplatin[CITED2 results in decreased susceptibility to Cisplatin] which results in decreased expression of and results in decreased acetylation of TP53 protein21660965
D002945Cisplatin[CITED2 results in decreased susceptibility to Cisplatin] which results in decreased phosphorylation of TP53 protein21660965
D002945CisplatinERCC1 mutant form inhibits the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of H2AFX protein]]]21875941
D002945CisplatinERCC1 mutant form inhibits the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of H2AFX protein]]21875941
D002945CisplatinERCC1 mutant form promotes the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form results in increased susceptibility to Cisplatin]]21875941
D002945CisplatinERCC5 mutant form inhibits the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of H2AFX protein]]]21875941
D002945CisplatinMelatonin inhibits the reaction [Cisplatin results in increased phosphorylation of and results in increased expression of TP53 protein]24799992
D002945CisplatinMIR630 mRNA inhibits the reaction [Cisplatin results in increased phosphorylation of TP53 protein]20145152
D002945CisplatinMSH2 protein promotes the reaction [Cisplatin results in increased phosphorylation of TP53 protein]21285353
D002945CisplatinNicotine inhibits the reaction [Cisplatin results in increased expression of TP53 protein]16601104
D002945CisplatinNoscapine promotes the reaction [Cisplatin results in increased expression of TP53 protein]20674069
D002945Cisplatinnutlin 3 promotes the reaction [Cisplatin results in increased expression of TP53 mRNA]21109480
D002945Cisplatinnutlin 3 promotes the reaction [Cisplatin results in increased expression of TP53 protein]21624110
D002945Cisplatinnutlin 3 promotes the reaction [Cisplatin results in increased localization of TP53 protein]21109480
D002945Cisplatin[nutlin 3 results in increased stability of TP53 protein] which results in increased susceptibility to Cisplatin21205074
D002945Cisplatinpifithrin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]21660965
D002945Cisplatinpifithrin inhibits the reaction [CITED2 mutant form promotes the reaction [Cisplatin results in increased expression of TP53 protein]]21660965
D002945CisplatinPiroxicam promotes the reaction [Cisplatin results in increased expression of TP53 protein]21858171
D002945CisplatinRAD23B mutant form inhibits the reaction [Cisplatin results in increased expression of TP53 protein]21742020
D002945CisplatinRRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of and results in increased activity of CHEK1 protein]]21875941
D002945CisplatinRRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of H2AFX protein]]21875941
D002945CisplatinRRM2 mutant form promotes the reaction [TP53 mutant form results in increased susceptibility to Cisplatin]21875941
D002945CisplatinSB 203580 inhibits the reaction [[Cisplatin co-treated with fisetin] results in increased phosphorylation of TP53 protein]21216935
D002945Cisplatinsodium arsenite inhibits the reaction [Cisplatin results in increased expression of TP53 protein]21696631
D002945Cisplatin[TFAP2A protein co-treated with TP53 gene mutant form] results in decreased susceptibility to Cisplatin21489314
D002945CisplatinTP53 affects the reaction [Cisplatin results in increased activity of and results in increased expression of CDKN1A protein]21624110
D002945CisplatinTP53 affects the reaction [Cisplatin results in increased activity of and results in increased expression of MDM2 protein]21624110
D002945CisplatinTP53 affects the reaction [Cisplatin results in increased expression of RRM2B protein]21875941
D002945CisplatinTP53 affects the reaction [CITED2 results in decreased susceptibility to Cisplatin]21660965
D002945CisplatinTP53 affects the reaction [nutlin 3 promotes the reaction [Cisplatin results in increased activity of and results in increased expression of CDKN1A protein]]21624110
D002945CisplatinTP53 affects the reaction [nutlin 3 promotes the reaction [Cisplatin results in increased activity of and results in increased expression of MDM2 protein]]21624110
D002945CisplatinTP53 gene mutant form results in decreased susceptibility to Cisplatin15578696
D002945CisplatinTP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of and results in increased activity of CHEK1 protein]21875941
D002945CisplatinTP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of H2AFX protein]21875941
D002945CisplatinTP53 mutant form results in increased susceptibility to Cisplatin21875941
D002945CisplatinTP53 protein affects the reaction [Cisplatin results in increased degradation of HIF1A protein]17498666
D002945CisplatinTP53 protein affects the reaction [Cisplatin results in increased expression of XPC protein]22331493
D002945CisplatinTP53 protein affects the reaction [Cisplatin results in increased susceptibility to TNFSF10 protein]21152876
D002945CisplatinTP53 protein affects the reaction [sodium arsenite results in increased susceptibility to Cisplatin]22331493
D002945CisplatinTP53 protein affects the susceptibility to Cisplatin22331493
D002945CisplatinTP53 protein affects the susceptibility to [Fluorouracil co-treated with Cisplatin]15999354
D002945Cisplatin[TP53 protein binds to MDM2 protein] which results in decreased susceptibility to Cisplatin21509038
D002945CisplatinTP53 protein inhibits the reaction [Cisplatin results in increased expression of CCNB1 protein]19548002
D002945CisplatinTP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Cisplatin]20623183
D002945CisplatinTP53 protein modified form affects the susceptibility to Cisplatin11861384
D002945CisplatinTP53 protein promotes the reaction [Cisplatin results in increased expression of PMAIP1 mRNA]17216584
D002945CisplatinTP53 protein promotes the reaction [Y 27632 results in decreased susceptibility to Cisplatin]20878077
D002945CisplatinTP53 protein results in decreased susceptibility to Cisplatin15990222|1602066
D002945CisplatinTP53 protein results in increased susceptibility to Cisplatin16193384|1621108
D002945CisplatinTP53 protein results in increased susceptibility to [Cisplatin co-treated with Fluorouracil]16077963
D002945CisplatinTP53 protein results in increased susceptibility to [Fluorouracil co-treated with Cisplatin]15254702
D002945CisplatinTP53 results in increased susceptibility to Cisplatin21258400
D002945CisplatinTretinoin inhibits the reaction [Cisplatin results in increased acetylation of TP53 protein]21532991
D002945CisplatinU 0126 inhibits the reaction [[Cisplatin co-treated with chrysin] affects the localization of TP53 protein]25770930
D002945CisplatinU 0126 inhibits the reaction [[Cisplatin co-treated with chrysin] results in increased phosphorylation of TP53 protein]25770930
D002945Cisplatinvorinostat inhibits the reaction [Tretinoin inhibits the reaction [Cisplatin results in increased acetylation of TP53 protein]]21532991
D002945CisplatinXPA mutant form inhibits the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of H2AFX protein]]]21875941
D002945CisplatinY 27632 inhibits the reaction [Cisplatin results in increased expression of TP53 mRNA]20878077
D002945CisplatinCisplatin results in increased phosphorylation of TP53 protein21151649
D002945CisplatinCisplatin results in increased acetylation of TP53 protein21416250
D002945CisplatinCisplatin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein15315938
D002945CisplatinCisplatin results in increased expression of TP53 mRNA25640527|2612002
D002945CisplatinCisplatin results in increased expression of TP53 protein20650967|2518474
D002945CisplatinCisplatin results in increased expression of TP53 protein modified form26739623
D002945CisplatinCisplatin results in increased phosphorylation of and results in increased stability of TP53 protein18310471
D002945Cisplatinfisetin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]25184746
D002945Cisplatinformononetin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]28414026
D002945CisplatinLovastatin inhibits the reaction [Cisplatin results in increased expression of TP53 protein modified form]26739623
D002945Cisplatinnaringin inhibits the reaction [Cisplatin results in increased expression of TP53 mRNA]26120027|2661265
D002945Cisplatinpifithrin inhibits the reaction [Cisplatin results in increased activity of TP53 protein]15315938
D002945Cisplatinpifithrin inhibits the reaction [TP53 protein results in increased susceptibility to Cisplatin]15315938
D002945CisplatinPlant Extracts inhibits the reaction [Cisplatin results in increased expression of TP53 mRNA]25640527
D002945CisplatinPravastatin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]20650967
D002945CisplatinTP53 protein mutant form inhibits the reaction [Cisplatin results in increased expression of MIR375 mRNA]28119452
D002945CisplatinTP53 protein results in increased susceptibility to Cisplatin15315938
D002945CisplatinCisplatin results in increased expression of TP5312712633|2060311
D002945Cisplatinmangostin inhibits the reaction [Cisplatin results in increased expression of TP53]20603111
D002945CisplatinCisplatin results in increased expression of TP53 protein21837762
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased activity of TP53 protein27589886
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased expression of TP53 mRNA19545618
D004006DichlorvosDichlorvos results in decreased expression of TP53 mRNA23053939
D004006DichlorvosDichlorvos results in increased expression of TP53 mRNA24369695
D004006DichlorvosDichlorvos results in increased expression of TP53 protein24369695
D004006DichlorvosTEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 mRNA]24369695
D004006DichlorvosTEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 protein]24369695
D004008DiclofenacDiclofenac affects the expression of TP53 mRNA24752500
C000944dicrotophosdicrotophos results in increased expression of TP53 mRNA28302478
D001728Dicumarol"Dicumarol inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein]"26630137
D001728Dicumarol"Dicumarol inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein modified form]"26630137
D001728DicumarolDicumarol inhibits the reaction [IL1B protein results in increased expression of TP53 protein]17959154
D001728DicumarolDicumarol inhibits the reaction [RB1CC1 protein results in increased expression of TP53 protein]16061648
D001728DicumarolDicumarol inhibits the reaction [RB1CC1 protein results in increased stability of TP53 protein]16061648
D001728DicumarolDicumarol inhibits the reaction [TP53 protein binds to NQO1 protein]14634213
D001728DicumarolDicumarol results in decreased expression of TP53 protein22692362
D001728DicumarolDicumarol results in increased degradation of TP53 protein14634213
D004026DieldrinDieldrin affects the expression of TP53 mRNA22546817
C020283diethanolaminediethanolamine results in decreased expression of TP53 mRNA16014740
C502471diethoxyphosphoryloxymethyl butanoatediethoxyphosphoryloxymethyl butanoate promotes the reaction [Doxorubicin results in increased acetylation of TP53 protein]16826403
C502471diethoxyphosphoryloxymethyl butanoatediethoxyphosphoryloxymethyl butanoate results in increased acetylation of TP53 protein16826403
C502471diethoxyphosphoryloxymethyl butanoateDoxorubicin promotes the reaction [diethoxyphosphoryloxymethyl butanoate results in increased acetylation of TP53 protein]16826403
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of TP53 mRNA27614199
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of TP53 mRNA28115068
D004051Diethylhexyl PhthalateEthanol promotes the reaction [Diethylhexyl Phthalate results in increased expression of TP53 mRNA]28115068
C014476diethyl maleateTP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein]27982581
C014476diethyl maleateTP53 protein affects the reaction [diethyl maleate results in increased expression of SRXN1 protein]27982581
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of TP53 protein21776270
D004052Diethylnitrosamine"[5,7-dimethoxyflavone co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA"21554863
D004052Diethylnitrosamine"[5,7-dimethoxyflavone co-treated with Diethylnitrosamine] results in increased expression of TP53 protein"21554863
D004052Diethylnitrosamine[Acetoxyacetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TP53 protein10741303
D004052DiethylnitrosamineAHR protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of TP53 protein]]15459018
D004052DiethylnitrosamineATM protein affects the reaction [Diethylnitrosamine results in increased expression of TP53 protein]11751435
D004052Diethylnitrosaminecaffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of TP53 mRNA]20360939
D004052DiethylnitrosamineCaffeine inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 protein]11751435
D004052DiethylnitrosamineCaffeine inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of TP53 protein]11751435
D004052Diethylnitrosaminechrysin inhibits the reaction [Diethylnitrosamine results in decreased expression of TP53 mRNA]21167192
D004052Diethylnitrosaminecobaltous chloride promotes the reaction [Diethylnitrosamine results in increased expression of TP53 protein]11751435
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of TP53 protein11003613
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of TP53 protein11915028
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of TP53 mRNA14633663
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein23665045
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with chrysin] results in increased expression of TP53 protein21167192
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of TP53 mRNA17602206
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA18544905
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of TP53 mRNA21167192|2155486
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of TP53 protein24954034
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of and results in increased phosphorylation of TP53 protein15459018
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of TP53 mRNA14555611|1987480
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of TP53 protein11751435|1455561
D004052DiethylnitrosamineDiethylnitrosamine results in increased phosphorylation of TP53 protein11751435
D004052DiethylnitrosamineDiosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein]23665045
D004052Diethylnitrosamine[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA21907755
D004052Diethylnitrosamine[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein21907755
D004052Diethylnitrosaminegeraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA]21907755
D004052Diethylnitrosaminegeraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein]21907755
D004052DiethylnitrosamineIFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of TP53 protein]11915028
D004052Diethylnitrosaminelanreotide inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 mRNA]19874807
D004052Diethylnitrosaminemyrtenal inhibits the reaction [[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA]22436021
D004052Diethylnitrosaminemyrtenal inhibits the reaction [[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 protein]22436021
D004052Diethylnitrosamine[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA22436021
D004052Diethylnitrosamine[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 protein22436021
D004052DiethylnitrosaminePhenobarbital promotes the reaction [Diethylnitrosamine results in increased expression of TP53 protein]11751435
D004052DiethylnitrosaminePlant Extracts inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 protein]18367157
D004052DiethylnitrosamineTetrachlorodibenzodioxin inhibits the reaction [Diethylnitrosamine results in increased expression of and results in increased phosphorylation of TP53 protein]15459018
D004052Diethylnitrosaminewortmannin inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 protein]11751435
D004052Diethylnitrosaminewortmannin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of TP53 protein]11751435
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of TP53 mRNA27825931
D004054Diethylstilbestrol[allyl sulfide co-treated with Diethylstilbestrol] results in increased expression of TP53 mRNA17125941
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of TP53 mRNA17125941
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of TP53 mRNA17011747
C011612diethyl sulfatediethyl sulfate results in decreased expression of TP53 protein23830811
C011612diethyl sulfatediethyl sulfate results in increased expression of TP53 protein23830811
D004074DigitoxinDigitoxin analog results in decreased expression of TP53 protein22037315
D004074DigitoxinDigitoxin results in decreased expression of TP53 protein22037315
C039060dihydroartemisinindihydroartemisinin results in increased phosphorylation of TP53 protein21547369
C012906dihydrocapsaicindihydrocapsaicin results in increased phosphorylation of TP53 protein19139269
C539241dihydroptychantol Adihydroptychantol A results in decreased expression of TP53 protein21185854
C539241dihydroptychantol Adihydroptychantol A results in increased expression of TP53 mRNA21185854
C539241dihydroptychantol Adihydroptychantol A results in increased phosphorylation of and results in increased localization of TP53 protein21185854
D002117CalcitriolCalcitriol results in increased expression of TP53 protein12071473
D0178784,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]"10951577
C012920dimefoxdimefox results in increased expression of TP53 mRNA18418871
C002302dimethoxondimethoxon results in decreased expression of TP53 mRNA28718371
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased activity of TP53 protein"20655369
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 protein"21294050
D0151279,10-Dimethyl-1,2-benzanthracene"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 protein]"21294050
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 mRNA"24269759
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of TP53 mRNA"24269759
D0198131,2-Dimethylhydrazine"1,2-Dimethylhydrazine results in decreased methylation of TP53 exon"8863662
D0198131,2-Dimethylhydrazine"1,2-Dimethylhydrazine results in increased expression of TP53 protein"18155637
D0198131,2-Dimethylhydrazine"Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased methylation of TP53 exon]"8863662
D0198131,2-Dimethylhydrazine"Vanadium inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of TP53 protein]"18155637
C065087di-n-butylphosphoric aciddi-n-butylphosphoric acid binds to TP53 protein24411723
C065087di-n-butylphosphoric aciddi-n-butylphosphoric acid binds to TP53 gene25510514
C076221dinophysistoxin 2dinophysistoxin 2 affects the localization of TP53 protein21512803
D004145DiosminDiosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein]23665045
D004147DioxinsDioxins affects the expression of TP53 mRNA20463971
D004147Dioxins3'-methoxy-4'-nitroflavone inhibits the reaction [Dioxins results in decreased expression of TP53 mRNA]15111621
D004147Dioxins3'-methoxy-4'-nitroflavone inhibits the reaction [Dioxins results in decreased expression of TP53 protein]15111621
D004147DioxinsAHR protein affects the reaction [Dioxins results in decreased expression of TP53 mRNA]15111621
D004147DioxinsDioxins results in decreased expression of TP53 mRNA15111621
D004147DioxinsDioxins results in decreased expression of TP53 protein15111621
D004229DithiothreitolDithiothreitol inhibits the reaction [[Cadmium Chloride results in decreased activity of TP53 protein] inhibits the reaction [TP53 protein binds to TP53 gene]]25446071|2544607
D004229DithiothreitolDithiothreitol inhibits the reaction [Glutathione Disulfide results in increased glutathionylation of TP53 protein]17555331
D004229DithiothreitolDithiothreitol inhibits the reaction [Glutathione results in increased glutathionylation of TP53 protein]17555331
D004050DitiocarbDitiocarb inhibits the reaction [cobaltous chloride results in increased expression of and results in increased activity of TP53 protein]10951577
D004050DitiocarbDitiocarb inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]10951577
D004050DitiocarbDitiocarb results in increased expression of TP53 protein11964141
C521792DMU-212DMU-212 results in increased expression of TP53 mRNA22687606|2405589
C067311docetaxel[docetaxel co-treated with alvocidib] results in increased expression of TP53 protein15297405
C067311docetaxeldocetaxel results in decreased expression of TP53 protein mutant form15970518
C067311docetaxeldocetaxel results in decreased ubiquitination of TP53 protein15970518
C067311docetaxeldocetaxel results in increased expression of TP53 mRNA16080190|2244586
C067311docetaxel[docetaxel results in increased expression of TP53 mRNA] which results in decreased expression of ABCB1 mRNA22445862
C067311docetaxeldocetaxel results in increased expression of TP53 protein15970518|1608019
C067311docetaxeldocetaxel results in increased ubiquitination of TP53 protein mutant form15970518
C067311docetaxel[fludarabine co-treated with Cytarabine co-treated with docetaxel] results in increased expression of TP53 protein9703875
C067311docetaxelTP53 promoter mutant form results in decreased susceptibility to docetaxel22445862
C067311docetaxelTP53 protein affects the reaction [docetaxel results in decreased expression of ABCB1 mRNA]22445862
C067311docetaxelTP53 protein inhibits the reaction [docetaxel results in increased expression of TUBB mRNA]16080190
D004281Docosahexaenoic AcidsDocosahexaenoic Acids affects the localization of TP53 protein28807874
D004281Docosahexaenoic AcidsOSGIN1 protein promotes the reaction [Docosahexaenoic Acids affects the localization of TP53 protein]28807874
C076946donepezildonepezil inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]19345205
D004298Dopamine[Dopamine results in increased expression of HIF1A protein] which results in increased expression of and results in increased phosphorylation of TP53 protein19410601
D004298Dopamine[Dopamine results in increased expression of HIF1A protein] which results in increased expression of TP53 protein19410601
D004317Doxorubicin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]]15763944
D004317Doxorubicin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]20856197
D004317Doxorubicin2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
D004317Doxorubicin3-methyladenine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
D004317Doxorubicin7-monohydroxyethylrutoside inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]17285121
D004317DoxorubicinAcetylcysteine inhibits the reaction [ATM protein promotes the reaction [Doxorubicin results in increased activity of TP53 protein]]15489221
D004317DoxorubicinAcetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]]15489221
D004317DoxorubicinAcetylcysteine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
D004317DoxorubicinANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]15763944
D004317Doxorubicin[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of TP53 mRNA24738333
D004317Doxorubicin[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of TP53 protein24738333
D004317DoxorubicinATM protein promotes the reaction [Doxorubicin results in increased activity of TP53 protein]15489221
D004317DoxorubicinCaffeine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
D004317DoxorubicinCDC25C protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]19074854
D004317DoxorubicinChloroquine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
D004317Doxorubicincobaltous chloride inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]19714248
D004317Doxorubicincobaltous chloride inhibits the reaction [[Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BAX mRNA]19714248
D004317Doxorubicincobaltous chloride inhibits the reaction [[Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3 mRNA]19714248
D004317Doxorubicincobaltous chloride inhibits the reaction [HIPK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]19714248
D004317DoxorubicinCSE1L protein promotes the reaction [Doxorubicin results in increased expression of TP53 protein]18377724
D004317Doxorubicindiethoxyphosphoryloxymethyl butanoate promotes the reaction [Doxorubicin results in increased acetylation of TP53 protein]16826403
D004317DoxorubicinDoxorubicin affects the expression of TP53 mRNA27825931
D004317DoxorubicinDoxorubicin affects the expression of TP53 protein12006519|1789351
D004317DoxorubicinDoxorubicin affects the localization of TP53 protein19363521
D004317Doxorubicin[Doxorubicin co-treated with Paclitaxel] results in increased expression of TP53 protein16168113
D004317Doxorubicin[Doxorubicin co-treated with resveratrol] results in increased expression of TP53 mRNA26969377
D004317Doxorubicin[Doxorubicin co-treated with resveratrol] results in increased expression of TP53 protein26969377
D004317Doxorubicin[Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of TP53 protein9815696
D004317DoxorubicinDoxorubicin inhibits the reaction [TP53 protein binds to MDM2 protein]19351845
D004317DoxorubicinDoxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]15489221
D004317DoxorubicinDoxorubicin promotes the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein]27634759
D004317DoxorubicinDoxorubicin promotes the reaction [diethoxyphosphoryloxymethyl butanoate results in increased acetylation of TP53 protein]16826403
D004317DoxorubicinDoxorubicin promotes the reaction [[TP53 protein binds to BBC3 promoter] which results in increased expression of BBC3 mRNA]19714248
D004317DoxorubicinDoxorubicin promotes the reaction [TP53 protein binds to BIRC5 promoter]17124180
D004317DoxorubicinDoxorubicin promotes the reaction [TP53 protein binds to CARM1 protein]19351845
D004317DoxorubicinDoxorubicin promotes the reaction [TP53 protein binds to CDKN1A promoter]19351845
D004317DoxorubicinDoxorubicin promotes the reaction [TP53 protein binds to CREBBP protein]19351845
D004317DoxorubicinDoxorubicin promotes the reaction [TP53 protein binds to ESR1 promoter]19351845
D004317DoxorubicinDoxorubicin promotes the reaction [TP53 protein binds to JUN protein]19351845
D004317DoxorubicinDoxorubicin promotes the reaction [TP53 protein binds to SP1 protein]19351845
D004317DoxorubicinDoxorubicin results in decreased expression of TP53 mRNA18510171
D004317DoxorubicinDoxorubicin results in increased acetylation of TP53 protein16826403
D004317DoxorubicinDoxorubicin results in increased acetylation of TP53 protein mutant form27129209
D004317Doxorubicin[Doxorubicin results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein27129209
D004317DoxorubicinDoxorubicin results in increased activity of TP53 protein15141020|1712418
D004317DoxorubicinDoxorubicin results in increased expression of and affects the phosphorylation of and results in increased localization of TP53 protein17653088
D004317DoxorubicinDoxorubicin results in increased expression of and results in increased phosphorylation of and results in increased acetylation of TP53 protein17634554
D004317DoxorubicinDoxorubicin results in increased expression of and results in increased phosphorylation of TP53 protein16432175|2716385
D004317DoxorubicinDoxorubicin results in increased expression of TP5316013437
D004317DoxorubicinDoxorubicin results in increased expression of TP53 mRNA15939500|1600197
D004317DoxorubicinDoxorubicin results in increased expression of TP53 protein10969820|1177985
D004317DoxorubicinDoxorubicin results in increased expression of TP53 protein modified form16857806
D004317DoxorubicinDoxorubicin results in increased glutathionylation of TP53 protein17555331
D004317DoxorubicinDoxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein19714248
D004317Doxorubicin[Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BAX mRNA19714248
D004317Doxorubicin[Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3 mRNA19714248
D004317DoxorubicinDoxorubicin results in increased phosphorylation of TP53 protein15177039|1567153
D004317DoxorubicinDoxorubicin results in increased stability of TP53 protein25124555
D004317DoxorubicinFluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of TP53 protein]16168113
D004317DoxorubicinGlutathione inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
D004317DoxorubicinHIPK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]19714248
D004317DoxorubicinIFNA1 protein promotes the reaction [Doxorubicin results in increased expression of TP53 protein]17959036
D004317DoxorubicinLovastatin inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]17088865
D004317DoxorubicinMDM2 protein inhibits the reaction [HIPK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]19714248
D004317DoxorubicinMDM2 protein promotes the reaction [cobaltous chloride inhibits the reaction [HIPK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]]19714248
D004317DoxorubicinNFKB1 protein affects the reaction [Doxorubicin results in increased expression of TP53 protein]17912235
D004317Doxorubicinnutlin 3 promotes the reaction [Doxorubicin results in increased expression of TP53 protein]21624110
D004317DoxorubicinPI103 inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]20856197
D004317Doxorubicinpluronic block copolymer p85 promotes the reaction [Doxorubicin results in increased expression of TP53 mRNA]15939500
D004317DoxorubicinSETD7 protein promotes the reaction [Doxorubicin results in increased stability of TP53 protein]25124555
D004317DoxorubicinTNF protein inhibits the reaction [TP53 gene mutant form results in decreased susceptibility to Doxorubicin]15823547
D004317DoxorubicinTP53 affects the reaction [Doxorubicin results in increased activity of and results in increased expression of CDKN1A protein]21624110
D004317DoxorubicinTP53 affects the reaction [Doxorubicin results in increased activity of and results in increased expression of MDM2 protein]21624110
D004317DoxorubicinTP53 affects the reaction [nutlin 3 promotes the reaction [Doxorubicin results in increased activity of and results in increased expression of CDKN1A protein]]21624110
D004317DoxorubicinTP53 affects the reaction [nutlin 3 promotes the reaction [Doxorubicin results in increased activity of and results in increased expression of MDM2 protein]]21624110
D004317DoxorubicinTP53 gene affects the susceptibility to Doxorubicin17085670
D004317DoxorubicinTP53 gene mutant form inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]15578696
D004317DoxorubicinTP53 gene mutant form results in decreased susceptibility to Doxorubicin15578696|1736960
D004317DoxorubicinTP53 protein affects the reaction [APP protein affects the susceptibility to Doxorubicin]17608641
D004317DoxorubicinTP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Doxorubicin]18698031
D004317DoxorubicinTP53 protein affects the reaction [Doxorubicin affects the reaction [RELA protein results in increased expression of CDKN1A mRNA]]18269916
D004317DoxorubicinTP53 protein affects the reaction [Doxorubicin results in decreased expression of BIRC5 protein]19363521
D004317DoxorubicinTP53 protein affects the reaction [Doxorubicin results in increased expression of CDKN1A mRNA]17079232
D004317DoxorubicinTP53 protein affects the reaction [Doxorubicin results in increased expression of ESR1 mRNA]19351845
D004317DoxorubicinTP53 protein affects the reaction [Doxorubicin results in increased expression of ESR1 protein]19351845
D004317DoxorubicinTP53 protein affects the reaction [Doxorubicin results in increased expression of GPX1 mRNA]15059885
D004317DoxorubicinTP53 protein affects the reaction [Doxorubicin results in increased expression of NFKB1 protein]17912235
D004317DoxorubicinTP53 protein affects the reaction [Doxorubicin results in increased expression of SOD2 mRNA]15059885
D004317DoxorubicinTP53 protein affects the reaction [FHL2 protein affects the reaction [Doxorubicin results in increased expression of CDKN1A protein]]17682292
D004317DoxorubicinTP53 protein affects the reaction [IFNA1 protein results in increased susceptibility to Doxorubicin]17959036
D004317DoxorubicinTP53 protein affects the susceptibility to Doxorubicin15182437|1791223
D004317DoxorubicinTP53 protein inhibits the reaction [Doxorubicin results in decreased activity of CDK2 protein]25124555
D004317DoxorubicinTP53 protein inhibits the reaction [Doxorubicin results in decreased expression of UBE2C protein]27129209
D004317DoxorubicinTP53 protein inhibits the reaction [Sildenafil Citrate results in increased susceptibility to Doxorubicin]20155316
D004317DoxorubicinTP53 protein mutant form affects the reaction [Doxorubicin results in decreased expression of BAX mRNA]24816189
D004317DoxorubicinTP53 protein mutant form affects the reaction [Doxorubicin results in decreased expression of SFN mRNA]24816189
D004317DoxorubicinTP53 protein mutant form affects the reaction [Doxorubicin results in increased expression of BAX protein]24816189
D004317DoxorubicinTP53 protein mutant form affects the reaction [Doxorubicin results in increased expression of BBC3 protein]24816189
D004317DoxorubicinTP53 protein mutant form affects the reaction [Doxorubicin results in increased expression of BCL2L1 protein]24816189
D004317DoxorubicinTP53 protein mutant form affects the reaction [Doxorubicin results in increased expression of CDKN1A mRNA]24816189
D004317DoxorubicinTP53 protein mutant form affects the reaction [Doxorubicin results in increased expression of SFN protein]24816189
D004317DoxorubicinTP53 protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]20856197
D004317DoxorubicinTP53 protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of CASP8 protein]]20856197
D004317DoxorubicinTP53 protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased cleavage of CASP9 protein]]20856197
D004317DoxorubicinTP53 protein promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Doxorubicin results in increased expression of and results in increased activity of BAX protein]]20856197
D004317DoxorubicinTP53 protein promotes the reaction [[Doxorubicin co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in increased expression of BBC3 protein]20856197
D004317DoxorubicinTP53 protein promotes the reaction [[Doxorubicin co-treated with PI103] results in increased expression of BBC3 protein]20856197
D004317DoxorubicinTP53 protein promotes the reaction [Doxorubicin results in increased expression of FAS mRNA]11779855
D004317DoxorubicinTP53 protein promotes the reaction [Doxorubicin results in increased expression of TNFSF10 mRNA]19106633
D004317DoxorubicinTP53 protein promotes the reaction [Doxorubicin results in increased expression of TNFSF10 protein]19106633
D004317DoxorubicinTP53 protein promotes the reaction [PI103 promotes the reaction [Doxorubicin results in increased activity of BAX protein]]20856197
D004317DoxorubicinTP53 protein promotes the reaction [PI103 promotes the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]20856197
D004317DoxorubicinTP53 protein promotes the reaction [PI103 promotes the reaction [Doxorubicin results in increased cleavage of CASP8 protein]]20856197
D004317DoxorubicinTP53 protein promotes the reaction [PI103 promotes the reaction [Doxorubicin results in increased cleavage of CASP9 protein]]20856197
D004317DoxorubicinTP53 protein results in increased susceptibility to Doxorubicin14704126|1560146
D004317DoxorubicinTP53 protein results in increased susceptibility to [Doxorubicin co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one]20856197
D004317DoxorubicinTP53 protein results in increased susceptibility to [Doxorubicin co-treated with PI103]20856197
D004317Doxorubicinwortmannin inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]]15489221
D004317Doxorubicinzinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]19714248
D004317DoxorubicinDoxorubicin results in increased expression of TP53 protein25896364
D004317DoxorubicinPSMB10 protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]25896364
D004317DoxorubicinPSMB8 protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]25896364
D004317DoxorubicinPSMB9 protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]25896364
D004317Doxorubicin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Doxorubicin results in increased phosphorylation of TP53 protein]18775851
D004317Doxorubicin7-monohydroxyethylrutoside inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]17285121
D004317DoxorubicinDoxorubicin affects the reaction [TP53 protein binds to HSPB1 protein]18263706
D004317Doxorubicin[Doxorubicin affects the reaction [TP53 protein binds to HSPB1 protein]] which results in increased expression of CDKN1A protein18263706
D004317DoxorubicinDoxorubicin promotes the reaction [TP53 protein binds to BAX promoter]22155320
D004317DoxorubicinDoxorubicin promotes the reaction [TP53 protein binds to BCL2 promoter]22155320
D004317DoxorubicinDoxorubicin results in decreased expression of TP53 mRNA27255381
D004317DoxorubicinDoxorubicin results in increased expression of and results in increased localization of TP53 protein modified form18775851
D004317DoxorubicinDoxorubicin results in increased expression of and results in increased phosphorylation of and results in increased stability of and results in increased activity of TP53 protein16687611
D004317DoxorubicinDoxorubicin results in increased expression of TP53 mRNA15667795|1863259
D004317DoxorubicinDoxorubicin results in increased expression of TP53 protein15983034|1728512
D004317DoxorubicinDoxorubicin results in increased phosphorylation of and results in increased localization of TP53 protein18775851
D004317DoxorubicinGinkgo biloba extract inhibits the reaction [Doxorubicin results in increased expression of TP53 mRNA]18632596
D004317Doxorubicin[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]25997894
D004317Doxorubicinkaempferol inhibits the reaction [Doxorubicin promotes the reaction [TP53 protein binds to BAX promoter]]22155320
D004317Doxorubicinkaempferol inhibits the reaction [Doxorubicin results in increased expression of TP53 mRNA]22155320
D004317Doxorubicinpifithrin inhibits the reaction [Doxorubicin results in increased expression of and results in increased localization of TP53 protein modified form]18775851
D004317Doxorubicinpifithrin inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein]16687611
D004317Doxorubicinpifithrin inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased localization of TP53 protein]18775851
D004317DoxorubicinPropofol inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22015447
D004317DoxorubicinQuercetin inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]24902966
D004317DoxorubicinSHC1 protein promotes the reaction [Doxorubicin results in increased expression of TP53 protein]26318906
D004317DoxorubicinU 0126 inhibits the reaction [Doxorubicin results in increased expression of and results in increased localization of TP53 protein modified form]18775851
D004317DoxorubicinU 0126 inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased localization of TP53 protein]18775851
D004317DoxorubicinDoxorubicin results in increased activity of TP53 protein18775851
D004317DoxorubicinTP53 protein affects the susceptibility to Doxorubicin15059885
C060327dracorhodindracorhodin analog results in increased expression of TP53 protein15684474
C060327dracorhodindracorhodin analog results in increased phosphorylation of TP53 protein15684474
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of TP53 protein"21457722
D004391DustDust results in decreased expression of TP53 mRNA17805423
D004492Edetic AcidEdetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP53 protein] inhibits the reaction [TP53 protein binds to TP53 gene]]25446071|2544607
D004492Edetic AcidEdetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP63 protein] inhibits the reaction [TP63 protein binds to TP53 gene]]25446071
D004492Edetic AcidEdetic Acid inhibits the reaction [[Cadmium Chloride results in decreased activity of TP73 protein] inhibits the reaction [TP73 protein binds to TP53 gene]]25446071
C004934eleostearic acideleostearic acid results in increased expression of TP53 protein15961301
D004610Ellagic AcidEllagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]15735102
D004610Ellagic AcidEllagic Acid results in increased expression of TP53 protein23554011
D004610Ellagic Acidpifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]]15735102
D004610Ellagic AcidEllagic Acid inhibits the reaction [phosalone results in increased expression of TP53 mRNA]27965107
D004610Ellagic AcidEllagic Acid inhibits the reaction [phosalone results in increased expression of TP53 protein]27965107
C561944EMD 534085EMD 534085 results in increased expression of TP53 protein modified form18451153
D004642EmodinEmodin affects the expression of TP53 protein19549930
C118739entinostatentinostat promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]25699604
C118739entinostatentinostat results in increased expression of TP53 protein25699604
C118739entinostatEtoposide promotes the reaction [entinostat results in increased expression of TP53 protein]25699604
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TP53 protein23301498
D015251Epirubicin"3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of TP53 mRNA]"22914566
D015251Epirubicinchrysophsin promotes the reaction [Epirubicin results in increased expression of TP53 mRNA]26335193
D015251Epirubicin[Epirubicin analog co-treated with chrysophsin analog] results in increased expression of TP53 mRNA26335193
D015251Epirubicin"Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of TP53 mRNA]"22914566
D015251EpirubicinEpirubicin promotes the reaction [chrysophsin results in increased expression of TP53 mRNA]26335193
D015251EpirubicinEpirubicin results in increased expression of TP53 mRNA22914566|2633519
C045651epigallocatechin gallateepigallocatechin gallate inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein]15795422
C045651epigallocatechin gallateepigallocatechin gallate results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein15764647
C045651epigallocatechin gallateepigallocatechin gallate results in increased expression of and results in increased phosphorylation of TP53 protein15657356|1940622
C045651epigallocatechin gallateepigallocatechin gallate results in increased expression of TP53 protein26341291
C045651epigallocatechin gallateepigallocatechin gallate results in increased expression of TP53 protein modified form26341291
C045651epigallocatechin gallateTP53 mRNA affects the susceptibility to epigallocatechin gallate19406223
C045651epigallocatechin gallateTP53 protein results in increased susceptibility to epigallocatechin gallate15764647|2328509
C045651epigallocatechin gallateepigallocatechin gallate affects the expression of TP53 protein22000973
C045651epigallocatechin gallateepigallocatechin gallate results in increased activity of TP53 promoter19406223
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride promotes the reaction [resveratrol results in increased expression of TP53 protein]25895606
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride results in increased expression of TP53 protein25895606
D000069347Erlotinib Hydrochlorideresveratrol promotes the reaction [Erlotinib Hydrochloride results in increased expression of TP53 protein]25895606
C007366erythritol anhydrideATM protein affects the reaction [erythritol anhydride results in increased phosphorylation of TP53 protein]20024960
C007366erythritol anhydrideerythritol anhydride inhibits the reaction [TP53 protein binds to MDM2 protein]20024960
C007366erythritol anhydrideerythritol anhydride results in increased acetylation of and results in increased phosphorylation of TP53 protein20024960
C007366erythritol anhydrideerythritol anhydride results in increased expression of and results in increased stability of TP53 protein20024960
C007366erythritol anhydrideerythritol anhydride results in increased expression of TP53 protein14998682
D004918Erythromycin EstolateErythromycin Estolate results in decreased expression of TP53 mRNA17522070
D004923ErythrosineErythrosine results in increased activity of TP53 protein9168006
C007628esculetinesculetin results in increased degradation of TP53 protein14634213
C074283estradiol 3-benzoateestradiol 3-benzoate results in increased expression of TP53 mRNA24316378
C074283estradiol 3-benzoateestradiol 3-benzoate results in increased expression of TP53 protein24316378
C074283estradiol 3-benzoateQuercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of TP53 mRNA]24316378
C074283estradiol 3-benzoateQuercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of TP53 protein]24316378
C007633estragoleestragole results in increased phosphorylation of TP53 protein29054680
D004967EstrogensEstrogens results in increased expression of TP53 mRNA18204794
D004966Estrogens, Conjugated (USP)"[Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate] results in decreased expression of TP53 protein"16021059
C088768estrone-3-O-sulfamateestrone-3-O-sulfamate analog results in increased expression of TP53 protein14991574
D004976Ethacrynic AcidEthacrynic Acid affects the localization of TP53 protein25817893
D000431EthanolEthanol results in increased expression of and results in increased phosphorylation of TP53 protein27270636
D000431EthanolMAPK14 protein promotes the reaction [Ethanol results in increased expression of and results in increased phosphorylation of TP53 protein]27270636
D000431EthanolSB 203580 inhibits the reaction [Ethanol results in increased expression of and results in increased phosphorylation of TP53 protein]27270636
D000431EthanolSIAH1 protein promotes the reaction [Ethanol results in increased expression of and results in increased phosphorylation of TP53 protein]27270636
D000431Ethanol[Ethanol co-treated with Cyanamide] results in increased expression of TP53 mRNA12003908
D000431EthanolEthanol promotes the reaction [Diethylhexyl Phthalate results in increased expression of TP53 mRNA]28115068
D000431EthanolEthanol results in increased acetylation of TP53 protein24769256
D000431EthanolEthanol results in increased expression of TP53 mRNA23273579
D000431Ethanolsalvianolic acid B inhibits the reaction [Ethanol results in increased acetylation of TP53 protein]24769256
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of TP53 mRNA20227414
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of TP53 mRNA16940010
D005028Ethylenebis(dithiocarbamates)Ethylenebis(dithiocarbamates) results in increased expression of TP53 protein11964141
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of TP53 gene14715658
D005038Ethylnitrosourea[Ethylnitrosourea results in increased mutagenesis of TP53 gene] which results in decreased activity of TP53 protein14715658|1471565
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of TP53 exon17156454
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of TP53 gene16495775
C054207etomoxiretomoxir results in increased expression of TP53 mRNA19234235
D005047Etoposide"2,4,4'-trichlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]"19751709
D005047Etoposide"2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]"19751709
D005047Etoposide"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]"19751709
D005047EtoposideCadmium Chloride affects the reaction [Etoposide results in increased phosphorylation of TP53 protein]25744307
D005047Etoposide[CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]21801448
D005047Etoposide[CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]21801448
D005047Etoposide[CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]21801448
D005047Etoposide[CASP8 co-treated with TP53] inhibits the reaction [CASP8 protein mutant form results in decreased susceptibility to Etoposide]21801448
D005047Etoposide[Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of TP53 protein9815696
D005047Etoposideentinostat promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]25699604
D005047EtoposideEtoposide promotes the reaction [entinostat results in increased expression of TP53 protein]25699604
D005047EtoposideEtoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA]11895857
D005047EtoposideEtoposide promotes the reaction [TP53 protein binds to TNFRSF10B promoter]15964798
D005047EtoposideEtoposide promotes the reaction [trichostatin A results in increased expression of TP53 protein]25699604
D005047EtoposideEtoposide promotes the reaction [UF010 compound results in increased expression of TP53 protein]25699604
D005047EtoposideEtoposide results in increased acetylation of TP53 protein20299546
D005047EtoposideEtoposide results in increased acetylation of TP53 protein mutant form27129209
D005047Etoposide[Etoposide results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein27129209
D005047EtoposideEtoposide results in increased activity of TP53 protein16120219|2065536
D005047EtoposideEtoposide results in increased expression of and results in increased acetylation of TP53 protein25699604
D005047EtoposideEtoposide results in increased expression of TP53 protein11895857|1208201
D005047Etoposide[Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein11895857
D005047EtoposideEtoposide results in increased phosphorylation of and affects the localization of TP53 protein26259609
D005047EtoposideEtoposide results in increased phosphorylation of and results in increased activity of TP53 protein16882877|2029954
D005047EtoposideEtoposide results in increased phosphorylation of TP53 protein21801448|2314469
D005047EtoposideNFE2L2 protein affects the reaction [Etoposide results in increased expression of TP53 protein]27982581
D005047EtoposideOxygen deficiency inhibits the reaction [Etoposide results in increased phosphorylation of TP53 protein]23144690
D005047Etoposidepifithrin inhibits the reaction [Etoposide results in increased activity of TP53 protein]16882877
D005047EtoposideTetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased acetylation of TP53 protein]20299546
D005047EtoposideTetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of TP53 protein]20299546
D005047EtoposideTP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]24067374
D005047EtoposideTP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]24067374
D005047EtoposideTP53 promotes the reaction [Etoposide results in increased expression of BTG2 protein]27358234
D005047EtoposideTP53 promotes the reaction [Etoposide results in increased expression of CDKN1A protein]27358234
D005047EtoposideTP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Etoposide]18698031
D005047EtoposideTP53 protein affects the reaction [Etoposide results in decreased expression of UBE2C mRNA]27129209
D005047EtoposideTP53 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]27982581
D005047EtoposideTP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Etoposide]20623183
D005047EtoposideTP53 protein inhibits the reaction [Etoposide results in decreased expression of UBE2C protein]27129209
D005047EtoposideTP53 protein results in increased susceptibility to Etoposide21552291
D005047EtoposideTP53 results in increased susceptibility to Etoposide16882877
D005047Etoposidetrichostatin A promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]25699604
D005047EtoposideUF010 compound promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]25699604
D005047Etoposidecordycepin promotes the reaction [Etoposide results in increased expression of TP53 protein]23690541
D005047EtoposideEtoposide promotes the reaction [Acetaminophen results in increased phosphorylation of TP53 protein]16330492
D005047EtoposideEtoposide results in increased expression of and results in increased phosphorylation of TP53 protein15459018
D005047EtoposideEtoposide results in increased expression of TP53 protein17516866|2369054
D005047EtoposideNiacin deficiency inhibits the reaction [Etoposide results in increased expression of TP53 protein]17516866
D005047EtoposideTetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of TP53 protein]15459018
D005047EtoposideEtoposide results in increased activity of TP53 protein18557930
D005054EugenolEugenol results in increased mutagenesis of TP53 gene15576237
D005054EugenolEugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TP53 protein]19851710
C433928EUK-134EUK-134 inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]25005833
C433928EUK-134EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of TP53 protein]25005833
C506425eurycomanoneeurycomanone results in decreased expression of TP53 protein21903368
D015025ZearalenoneAcetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]]29109043
D015025ZearalenoneAcetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA]]29109043
D015025ZearalenoneAcetylcysteine promotes the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]29109043
D015025Zearalenonedeoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]29109043
D015025Zearalenonefumonisin B1 inhibits the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]29109043
D015025Zearalenonefumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]29109043
D015025ZearalenoneZearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA]29109043
D015025ZearalenoneZearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA]29109043
D015025ZearalenoneZearalenone results in increased expression of TP53 mRNA29109043
C052498FEC protocol[FEC protocol co-treated with Celecoxib] results in decreased expression of TP53 protein16507397
D005273FenbendazoleFenbendazole results in increased expression of TP53 protein23411599
D011345FenofibrateFenofibrate affects the activity of TP53 protein25596134
D011345FenofibrateFenofibrate affects the activity of TP53 protein25596134
D011345FenofibrateFenofibrate results in increased expression of TP53 mRNA17264098
D005290Ferric CompoundsFerric Compounds results in increased expression of TP53 mRNA24035972
D005290Ferric CompoundsFerric Compounds results in increased expression of TP53 protein24035972
C020326ferric nitrilotriacetate[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA21907755
C020326ferric nitrilotriacetate[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein21907755
C020326ferric nitrilotriacetategeraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA]21907755
C020326ferric nitrilotriacetategeraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein]21907755
C000499ferric oxide[ferric oxide analog co-treated with Acrolein] results in increased expression of TP53 protein24847785
C000499ferric oxideferric oxide analog results in increased phosphorylation of TP53 protein22995439
C008169ferric oxide, saccharated"ferric oxide, saccharated results in increased expression of TP53 protein"16957011
C421458ferric-sorbitol-citrateferric-sorbitol-citrate results in increased expression of TP5317257079
D000068876Fingolimod HydrochlorideAcetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein]25939952
D000068876Fingolimod HydrochlorideFingolimod Hydrochloride results in increased phosphorylation of TP53 protein25939952
D000068876Fingolimod Hydrochloridenecrostatin-1 inhibits the reaction [Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein]25939952
D000068876Fingolimod Hydrochloridepyrazolanthrone inhibits the reaction [Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein]25939952
D000068876Fingolimod HydrochlorideRIPK3 mutant form inhibits the reaction [Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein]25939952
C082360fipronilfipronil affects the localization of TP53 protein21296133
C017875fisetin[Cisplatin co-treated with fisetin] affects the localization of TP53 protein21216935
C017875fisetin[Cisplatin co-treated with fisetin] results in increased expression of TP53 protein21216935
C017875fisetin[Cisplatin co-treated with fisetin] results in increased phosphorylation of TP53 protein21216935
C017875fisetinfisetin affects the localization of TP53 protein21216935
C017875fisetinfisetin inhibits the reaction [Silicon Dioxide results in increased expression of TP53 mRNA]22931364
C017875fisetinfisetin results in increased expression of TP53 protein21216935
C017875fisetinSB 203580 inhibits the reaction [[Cisplatin co-treated with fisetin] results in increased phosphorylation of TP53 protein]21216935
C017875fisetinfisetin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]25184746
C061872FK 409FK 409 results in increased expression of TP53 protein9888876
D005411Flame RetardantsFlame Retardants results in increased expression of TP53 mRNA19356805
D005411Flame RetardantsFlame Retardants results in decreased expression of TP53 mRNA26808241
D005411Flame RetardantsFlame Retardants results in increased expression of TP53 mRNA19858236
C028610flavanoneflavanone results in increased expression of and results in increased phosphorylation of TP53 protein22056764
D044950FlavanonesFlavanones results in increased expression of TP53 protein21616090
D044950FlavanonesTP53 gene mutant form promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]21616090
D044950FlavanonesTP53 gene mutant form promotes the reaction [Flavanones results in increased phosphorylation of H2AFX protein]21616090
D044950FlavanonesTP53 protein results in decreased susceptibility to Flavanones21616090
D005419FlavonoidsFlavonoids results in increased activity of TP53 protein12082016
D005467FloxuridineFloxuridine results in increased expression of TP53 protein19015155
C075780fluazinamfluazinam results in increased expression of TP53 protein21907236
C024352fludarabine[fludarabine co-treated with Cytarabine co-treated with docetaxel] results in increased expression of TP53 protein9703875
C024352fludarabinefludarabine results in increased expression of and results in increased phosphorylation of TP53 protein16439677
C024352fludarabinefludarabine results in increased expression of TP53 protein18092340
C024352fludarabineTP53 protein affects the susceptibility to fludarabine17226861
C007738fluoranthenefluoranthene promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]22120587
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of TP53 protein12888115
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in decreased expression of TP53 protein19167416
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of TP53 protein10708481|1556565
D0150732-Acetylaminofluorene[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of TP53 protein11003613
D0150732-Acetylaminofluorene[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of TP53 protein11915028
D0150732-Acetylaminofluorene[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of TP53 mRNA14633663
D0150732-Acetylaminofluorene[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein23665045
D0150732-AcetylaminofluoreneDiosmin inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TP53 protein]23665045
D0150732-AcetylaminofluoreneIFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of TP53 protein]11915028
D0150732-AcetylaminofluoreneVanadium promotes the reaction [2-Acetylaminofluorene results in increased expression of TP53 protein]15565650
D005437FlucytosineFlucytosine results in increased expression of TP53 protein15592511
D005472Fluorouracilanacardic acid inhibits the reaction [[Fluorouracil results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein]27129209
D005472FluorouracilCadmium Chloride affects the reaction [Fluorouracil affects the phosphorylation of TP53 protein]23941782
D005472FluorouracilCadmium Chloride affects the reaction [Fluorouracil results in increased expression of TP53 mRNA]23941782
D005472FluorouracilCadmium Chloride affects the reaction [Fluorouracil results in increased phosphorylation of TP53 protein]25744307
D005472Fluorouracil[CHEK1 protein co-treated with TP53 protein] affects the susceptibility to Fluorouracil18698031
D005472FluorouracilCycloheximide inhibits the reaction [Fluorouracil results in increased expression of TP53 protein]15016801
D005472FluorouracilFluorouracil affects the phosphorylation of TP53 protein23941782
D005472FluorouracilFluorouracil affects the reaction [Cadmium Chloride affects the phosphorylation of TP53 protein]23941782
D005472FluorouracilFluorouracil affects the reaction [Cadmium Chloride results in increased expression of TP53 mRNA]23941782
D005472Fluorouracil[Fluorouracil co-treated with Genistein] results in increased expression of TP53 mRNA15896711
D005472Fluorouracil[Fluorouracil co-treated with olaparib] results in increased expression of TP53 protein26544897
D005472FluorouracilFluorouracil promotes the reaction [allose results in increased expression of TP53 protein]18930000
D005472FluorouracilFluorouracil promotes the reaction [andrographolide results in increased expression of TP53]19097688
D005472FluorouracilFluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of TP53 protein]16168113
D005472FluorouracilFluorouracil promotes the reaction [TP53 protein binds to CES2 intron]16963839
D005472FluorouracilFluorouracil promotes the reaction [[TP53 protein binds to SP1 protein] which binds to CDKN1A promoter]15489892
D005472FluorouracilFluorouracil promotes the reaction [TP53 protein mutant form binds to UBE2C promoter]27129209
D005472FluorouracilFluorouracil results in decreased degradation of TP53 protein15625077
D005472FluorouracilFluorouracil results in decreased expression of TP53 mRNA16709241|1893000
D005472FluorouracilFluorouracil results in increased acetylation of TP53 protein mutant form27129209
D005472Fluorouracil[Fluorouracil results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein27129209
D005472FluorouracilFluorouracil results in increased activity of TP53 protein18779317|1901088
D005472FluorouracilFluorouracil results in increased expression of and results in increased phosphorylation of TP53 protein17634554|1798267
D005472FluorouracilFluorouracil results in increased expression of TP5311750847|1464655
D005472FluorouracilFluorouracil results in increased expression of TP53 mRNA12792779|2244586
D005472FluorouracilFluorouracil results in increased expression of TP53 protein12082016|1279277
D005472FluorouracilFluorouracil results in increased phosphorylation of and results in increased activity of TP53 protein16963839
D005472FluorouracilFluorouracil results in increased phosphorylation of TP53 protein15489892|1797176
D005472FluorouracilGenistein promotes the reaction [Fluorouracil results in increased expression of TP53 protein]15896711
D005472FluorouracilIFNA1 protein promotes the reaction [Fluorouracil results in increased phosphorylation of TP53 protein]17971768
D005472Fluorouracil"N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of TP53 protein]"15546879
D005472Fluorouracil[nutlin 3 results in increased stability of TP53 protein] which results in increased susceptibility to Fluorouracil21205074
D005472FluorouracilPravastatin inhibits the reaction [Fluorouracil results in decreased degradation of TP53 protein]15625077
D005472Fluorouracil[TP53 affects the expression of TYMS] which affects the susceptibility to Fluorouracil18600534
D005472FluorouracilTP53 affects the reaction [resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]]18497562
D005472FluorouracilTP53 gene mutant form affects the reaction [benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AFX protein]]26544897
D005472FluorouracilTP53 gene polymorphism affects the susceptibility to Fluorouracil18498133
D005472FluorouracilTP53 promoter mutant form results in decreased susceptibility to Fluorouracil22445862
D005472FluorouracilTP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Fluorouracil]18698031
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil promotes the reaction [E2F4 protein binds to UBE2C promoter]]27129209
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of AARS mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ACKR3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ACTL8 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ACY1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM10 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAM3A mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ADAMTS9 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of AGR2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ALG3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ANLN mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ANP32E mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of AP3S1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ARMCX1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ASAH1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ATP5F1D mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ATXN10 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of BCAT1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of BNIP3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of BOP1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CA14 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CAD mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CANX mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CBS mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CCND2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CD52 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CD8A mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CDC20 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CDKN3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CHEK1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CHRNA4 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CLTC mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of COL6A3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CPD mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CP mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYGS mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CRYL1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CSE1L mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CUTC mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CYC1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of DCK mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of DCLK1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of DCXR mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of DIMT1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of DLC1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of DLK1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of DTYMK mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of EGFR protein]17982676
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of EHF mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of EIF4E mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of EIPR1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of EP400 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ETF1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ETS1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of FAH mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of FAM107B mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of FKBP5 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of GAMT mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of GCSH mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of GDF1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of GPX2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of GSPT1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of GYG2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of H2AFX mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HAND1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HBA1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HDGFL3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HERPUD1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HIST1H4B mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HMG1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HMMR mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPA2B1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPF mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPH1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HNRNPL mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of HPX mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of IFI16 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of INPP5E mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of IQGAP2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ITPR1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of KCNQ2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of KIF15 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of KIF23 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of KLF5 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of KPNA2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of L1TD1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of LDHA mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of LRBA mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of LYPLA1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of MACF1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of MAP4K5 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of MARS mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM6 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM7 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of METAP2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of MMP1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of MMS19 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of NASP mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of NBN mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of NCAPG mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of NEK2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of NIPSNAP2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of NR1D2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of NUCKS1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ODC1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of OXCT1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PAFAH1B1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PAIP1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PDCD1LG2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PFN2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PGLYRP1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PHIP mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PI4KB mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PLK1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PMF1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PMS2P4 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PPA2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PPP1CC mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PREPL mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PRKAG2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PRKCI mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PRKDC mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PTTG1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PTTG3P mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of PURG mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of QSOX1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of RANBP1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of RECQL4 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of RFC4 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of RPL10A mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SAH mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SAP30 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SEC31B mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SELENOP mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SERPINA7 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SERPIND1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SEZ6L mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SF3B3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SHMT2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SIGLEC9 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SMS mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SP3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SPAG5 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SRP9 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of SRSF6 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TBCD mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TERT mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TFF1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TFRC mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TOP2A mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TRAP1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TROAP mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TSPO mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TUBA4B mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TXNIP mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of TXNRD3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of UBE2C mRNA]27129209
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of UBE2S mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of UGT8 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of UQCRB mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of USH2A mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of VANGL2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of WARS mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of WDR61 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of WEE1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of WTAP mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of YARS mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ZIM2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ZMYND8 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of ZNF266 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of ANXA2 mRNA]15152939
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of ATF3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 protein]14665630
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of BDKRB2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of BTG2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of CES2 mRNA]16963839
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of CNK mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP14 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP5 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of EPHA2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of FAS mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of FAS protein]15161716
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of FDXR mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of FMOD mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of GADD45A mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of GDF15 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of GJC1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of ID2B mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of IER5 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of INKA2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of NINJ1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of PLK2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of PMAIP1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of PPM1D mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of PROCR mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of RPS27L mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of RRM2B mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of S100A2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of SAT1 mRNA]15152939
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of SERPINB5 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of SERTAD1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of SESN1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of SESN2 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of SFN mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of TGFA mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of TIGAR mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of TLR3 mRNA]18779317
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of TNFRSF10D mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of TOB1 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of TP53I3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of TP53INP1 mRNA]15016801
D005472FluorouracilTP53 protein affects the susceptibility to Fluorouracil14665630|1504173
D005472FluorouracilTP53 protein affects the susceptibility to [Fluorouracil co-treated with Cisplatin]15999354
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of ANLN mRNA]17982676
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of BRCA1 mRNA]17982676
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNA2 protein]15546879
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]17982676
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 protein]15546879
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCND1 protein]17982676
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CRYZ mRNA]17982676
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of SCD mRNA]17982676
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of UBE2C mRNA]27129209
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of UBE2C protein]27129209
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of VEGFA mRNA]17982676
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]15546879
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in increased expression of CHEK1 protein]15016801
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in increased expression of EEF1A1 mRNA]17982676
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in increased expression of PLK1 protein]15016801
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in increased expression of PTTG1 protein]15016801
D005472Fluorouracil"TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]]"15546879
D005472Fluorouracil"TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]]"15546879
D005472Fluorouracil"TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]]"15546879
D005472FluorouracilTP53 protein mutant form affects the reaction [Fluorouracil promotes the reaction [NFYA protein binds to UBE2C promoter]]27129209
D005472FluorouracilTP53 protein mutant form affects the reaction [Fluorouracil promotes the reaction [NFYB protein binds to UBE2C promoter]]27129209
D005472Fluorouracil"TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]]"15546879
D005472Fluorouracil"TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]]"15546879
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in decreased expression of ECT2 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in decreased expression of MYC mRNA]16557594
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased cleavage of PARP1 protein]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of BTG2 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 mRNA]17637740
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of CASP8 protein]17637740
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of CCNG1 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]16557594
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein]15546879|1769979
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of CYFIP2 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of DDB2 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of DRAM1 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of FAS protein]15546879|1798267
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR mRNA]17982676|2296630
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of FDXR protein]22966307
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of GADD45A mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of GPX1 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of ID1 mRNA]16557594
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of ID2 mRNA]16557594
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of IKBIP mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of MDM2 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of MDM2 protein]15546879
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of PLK2 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of PPM1D mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of S100A2 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of SERPINB5 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of SESN1 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of SFN mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of TAP1 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of TNFRSF10B mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of TNFSF10 mRNA]19106633
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of TNFSF10 protein]19106633
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of TP53I3 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of TP53INP1 mRNA]16557594|1798267
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of TRIAP1 mRNA]17982676
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased expression of ZMAT3 mRNA]17982676
D005472Fluorouracil"TP53 protein promotes the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]]"15546879
D005472FluorouracilTP53 protein results in increased susceptibility to [Cisplatin co-treated with Fluorouracil]16077963
D005472FluorouracilTP53 protein results in increased susceptibility to Fluorouracil14704126|1668693
D005472FluorouracilTP53 protein results in increased susceptibility to [Fluorouracil co-treated with Cisplatin]15254702
D005472FluorouracilTP53 results in increased susceptibility to Fluorouracil14646558
D005472FluorouracilTP53 results in increased susceptibility to [Poly I-C co-treated with Fluorouracil]20367642
D005472FluorouracilFluorouracil promotes the reaction [Acetaminophen results in increased phosphorylation of TP53 protein]16330492
D005472FluorouracilFluorouracil results in increased expression of TP53 protein15459018
D005472FluorouracilTetrachlorodibenzodioxin inhibits the reaction [Fluorouracil results in increased expression of TP53 protein]15459018
D005472FluorouracilFluorouracil results in increased activity of TP53 protein19098008
D005472FluorouracilFluorouracil results in increased expression of TP5320633010
D005473FluoxetineFluoxetine results in increased expression of TP53 mRNA18836303
D005480FlurbiprofenFlurbiprofen results in increased abundance of and results in increased phosphorylation of TP53 protein15710360
D005480FlurbiprofenFlurbiprofen results in increased expression of TP53 protein11687965
D005480FlurbiprofenTP53 protein mutant form results in decreased susceptibility to Flurbiprofen15710360
D005480FlurbiprofenTP53 protein results in increased susceptibility to Flurbiprofen15710360
D005485FlutamideFlutamide results in decreased expression of TP53 mRNA21126777
D005485FlutamideFlutamide results in decreased expression of TP53 mRNA24793618
D005485FlutamideFlutamide results in increased expression of TP53 mRNA24136188
D005492Folic AcidFolic Acid affects the expression of TP53 mRNA16361273|1661137
D005492Folic AcidFolic Acid affects the expression of TP53 protein16361273
D005492Folic AcidFolic Acid inhibits the reaction [Methotrexate results in increased expression of TP53 mRNA]22183962
D005492Folic AcidFolic Acid affects the methylation of TP53 protein17056795
D005492Folic Acid[Folic Acid co-treated with Isoflavones] results in decreased expression of TP53 protein20060418
D005492Folic Acid"Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased methylation of TP53 exon]"8863662
D005557FormaldehydeFormaldehyde results in increased expression of TP53 mRNA22525295
D005557FormaldehydeFormaldehyde results in increased expression of TP53 protein15715472|2252529
C030544formic acidformic acid inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]10942736
C007768formononetinformononetin results in decreased expression of TP53 protein28414026
C007768formononetinXI-006 inhibits the reaction [formononetin results in decreased expression of TP53 protein]28414026
C007768formononetinformononetin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]28414026
C040313fostriecinfostriecin promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]24954032
C054368fotemustinefotemustine promotes the reaction [TP53 protein binds to POLH promoter]25125662
C054368fotemustinefotemustine results in increased expression of TP53 protein25125662
C054368fotemustinefotemustine results in increased expression of TP53 protein modified form25125662
C096856FTI 277FTI 277 inhibits the reaction [lopinavir-ritonavir drug combination results in increased expression of TP53 protein]20884875
C096856FTI 277FTI 277 inhibits the reaction [Ritonavir results in increased expression of TP53 protein]20884875
C069837fullerene C60fullerene C60 analog results in increased phosphorylation of and results in increased expression of TP53 protein20045429
C069837fullerene C60fullerene C60 results in decreased expression of TP53 mRNA19167457
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol affects the localization of TP53 protein]15870704
C070081fulvestrantfulvestrant results in decreased expression of TP53 protein24169358
C056933fumonisin B1[fumonisin B1 results in decreased chemical synthesis of Ceramides] which affects the splicing of and results in decreased expression of TP53 mRNA25195822
C056933fumonisin B1[fumonisin B1 results in decreased chemical synthesis of Ceramides] which results in decreased phosphorylation of TP53 protein modified form25195822
C056933fumonisin B1fumonisin B1 results in decreased expression of TP53 mRNA27757495
C056933fumonisin B1Acetylcysteine inhibits the reaction [Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression of TP53 protein]]28181396
C056933fumonisin B1Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Aflatoxin B1 results in increased expression of TP53 protein]]28181396
C056933fumonisin B1Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression of TP53 protein]28181396
C056933fumonisin B1fumonisin B1 promotes the reaction [Aflatoxin B1 results in increased expression of TP53 protein]28181396
C056933fumonisin B1fumonisin B1 results in increased expression of TP53 protein28181396
C056933fumonisin B1Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]]29109043
C056933fumonisin B1Acetylcysteine inhibits the reaction [Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA]]29109043
C056933fumonisin B1[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA29109043
C056933fumonisin B1fumonisin B1 inhibits the reaction [deoxynivalenol inhibits the reaction [Zearalenone results in increased expression of TP53 mRNA]]29109043
C056933fumonisin B1fumonisin B1 promotes the reaction [Zearalenone results in increased expression of TP53 mRNA]29109043
C056933fumonisin B1fumonisin B1 results in increased expression of TP53 mRNA29109043
C056933fumonisin B1Zearalenone promotes the reaction [[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TP53 mRNA]29109043
C056933fumonisin B1Zearalenone promotes the reaction [fumonisin B1 results in increased expression of TP53 mRNA]29109043
D062610Fungal PolysaccharidesFungal Polysaccharides results in increased expression of TP53 mRNA27181935
C039281furanfuran results in increased expression of TP53 protein20124500
C039281furanfuran results in increased methylation of TP53 gene22079235
D005690GalactoseGalactose results in increased expression of TP53 protein23036742
D005690GalactosePhycocyanin inhibits the reaction [Galactose results in increased expression of TP53 protein]23036742
D005690Galactose[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]25997894
D005707Gallic AcidGallic Acid results in decreased expression of TP53 mRNA21887735
D015774GanciclovirGanciclovir results in increased expression of TP53 protein15592511
C419708gefitinibTP53 protein affects the susceptibility to gefitinib21216229
C419708gefitinib[TP53 protein results in decreased expression of AURKA protein] which results in increased susceptibility to gefitinib21216229
C419708gefitinibgefitinib results in increased expression of TP53 mRNA27084042
C419708gefitinibgefitinib results in increased expression of TP53 protein27084042
C001277geldanamycingeldanamycin affects the expression of TP53 protein24211270
C001277geldanamycingeldanamycin affects the localization of TP53 protein17293044
C001277geldanamycinTretinoin inhibits the reaction [geldanamycin affects the localization of TP53 protein]17293044
C056507gemcitabinegemcitabine results in increased expression of TP53 protein12082016|1660110
C056507gemcitabineNicotine inhibits the reaction [gemcitabine results in increased expression of TP53 protein]16601104
C056507gemcitabine[TFAP2A protein co-treated with TP53 gene mutant form] results in decreased susceptibility to gemcitabine21489314
D019833Genisteinanacardic acid inhibits the reaction [Genistein promotes the reaction [trichostatin A results in increased acetylation of TP53 protein]]26768552
D019833GenisteinATM protein affects the reaction [Genistein results in increased expression of and results in increased phosphorylation of TP53 protein]15177039
D019833GenisteinEP300 promotes the reaction [Genistein promotes the reaction [trichostatin A results in increased expression of TP53 mRNA]]26768552
D019833GenisteinEP300 promotes the reaction [Genistein promotes the reaction [trichostatin A results in increased expression of TP53 protein]]26768552
D019833Genistein[Fluorouracil co-treated with Genistein] results in increased expression of TP53 mRNA15896711
D019833GenisteinGenistein affects the expression of TP53 mRNA18431742
D019833GenisteinGenistein affects the expression of TP53 protein18431742
D019833Genistein[Genistein co-treated with trichostatin A] results in increased expression of TP53 protein22626855
D019833GenisteinGenistein inhibits the reaction [HIST3H3 protein modified form binds to TP53 promoter]18431742
D019833GenisteinGenistein inhibits the reaction [SIRT1 protein binds to TP53 promoter]18431742
D019833GenisteinGenistein promotes the reaction [Fluorouracil results in increased expression of TP53 protein]15896711
D019833GenisteinGenistein promotes the reaction [trichostatin A results in increased expression of and results in increased acetylation of TP53 protein]26768552
D019833GenisteinGenistein promotes the reaction [trichostatin A results in increased expression of TP53 mRNA]26768552
D019833GenisteinGenistein results in increased expression of and results in increased phosphorylation of TP53 protein15177039
D019833Genistein[[Genistein results in increased expression of PTEN protein] which results in decreased activity of AKT1 protein] which results in increased expression of TP53 protein18431742
D019833GenisteinGenistein results in increased expression of TP53 protein19800779
D019833GenisteinTP53 protein results in increased susceptibility to Genistein26768552
D019833GenisteinGenistein results in increased activity of TP53 protein15177039
D005839GentamicinsGentamicins results in increased expression of TP53 mRNA22061828
C007836geraniolgeraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA]21907755
C007836geraniolgeraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein]21907755
C040155geranylgeranic acidgeranylgeranic acid affects the localization of TP53 protein mutant form24658405
C040155geranylgeranic acidIvermectin inhibits the reaction [geranylgeranic acid affects the localization of TP53 protein mutant form]24658405
C040155geranylgeranic acidTP53 protein results in decreased susceptibility to geranylgeranic acid24658405
C007845gingerolgingerol results in increased expression of TP53 protein18030663|2503453
C007845gingerol[gingerol results in increased expression of TP53 protein] which results in increased susceptibility to TNFSF10 protein25034532
C007845gingerol[Testosterone co-treated with gingerol] results in increased expression of TP53 protein18030663
C007845gingerolTP53 protein affects the reaction [gingerol results in increased expression of TNFRSF10B protein]25034532
C007845gingerolTP53 protein affects the reaction [gingerol results in increased susceptibility to TNFSF10 protein]25034532
C063170Ginkgo biloba extractGinkgo biloba extract inhibits the reaction [Doxorubicin results in increased expression of TP53 mRNA]18632596
D005897GlafenineGlafenine results in increased expression of TP53 mRNA24136188
D005947GlucoseGlucose affects the localization of TP53 protein24218232
D005947Glucose"Glucose inhibits the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
D005947GlucoseGlucose results in increased acetylation of TP53 protein20068143
D005947GlucoseGlucose results in increased expression of TP53 mRNA27049278
D005947GlucoseGlucose results in increased expression of TP53 protein26188290
D005947Glucose[Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein24451382
D005947Glucose[resveratrol co-treated with AICA ribonucleotide] inhibits the reaction [Glucose results in increased expression of TP53 protein]26188290
D005947Glucoseresveratrol inhibits the reaction [Glucose affects the localization of TP53 protein]24218232
D005947Glucoseresveratrol inhibits the reaction [Glucose results in increased acetylation of TP53 protein]20068143
D005947Glucoseresveratrol inhibits the reaction [Glucose results in increased expression of TP53 mRNA]27049278
D005947Glucoseresveratrol inhibits the reaction [Glucose results in increased expression of TP53 protein]26188290
D005947GlucoseSIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein]24451382
D005947GlucoseSIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in increased acetylation of TP53 protein]]20068143
D005947Glucose"[Tretinoin results in increased uptake of Glucose] inhibits the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
D005947Glucose[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]25997894
D005947Glucose[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of TP53 protein23451161
D005947GlucoseTP53 protein affects the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NDRG2]23451161
D005947GlucoseTP53 protein affects the susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]23451161
D005978Glutathione[Buthionine Sulfoximine results in decreased abundance of Glutathione] inhibits the reaction [Benzo(a)pyrene results in increased activity of TP53 protein]12807757
D005978GlutathioneDithiothreitol inhibits the reaction [Glutathione results in increased glutathionylation of TP53 protein]17555331
D005978GlutathioneGlutathione inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein]27634759
D005978GlutathioneGlutathione inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]19202565
D005978GlutathioneGlutathione inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22927544
D005978GlutathioneGlutathione results in increased expression of TP53 protein10897038
D005978GlutathioneGlutathione results in increased glutathionylation of TP53 protein17555331
D005978GlutathioneTP53 protein results in decreased abundance of Glutathione12967322
D019803Glutathione DisulfideDithiothreitol inhibits the reaction [Glutathione Disulfide results in increased glutathionylation of TP53 protein]17555331
D019803Glutathione DisulfideGlutathione Disulfide results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein15993333
D019803Glutathione DisulfideGlutathione Disulfide results in increased glutathionylation of TP53 protein17555331
D005990GlycerolGlycerol results in increased activity of TP53 protein mutant form15975526
C071834glycidamideglycidamide results in increased mutagenesis of TP53 gene15240786
C086566glyciteinglycitein results in increased expression of TP53 protein19800779
C024033glycoursodeoxycholic acidglycoursodeoxycholic acid inhibits the reaction [TP53 protein results in increased expression of BAX mRNA]17881359
C010974glyphosateglyphosate results in increased expression of TP53 mRNA25636363
D006046GoldGold analog results in increased expression of TP53 mRNA23549158
D006046GoldGold results in increased expression of TP53 mRNA22094122
C103280goniothalamingoniothalamin results in increased activity of TP53 protein21810437
C103280goniothalamingoniothalamin results in increased expression of TP53 protein20498002
C103280goniothalamingoniothalamin results in increased localization of TP53 protein21810437
C103280goniothalamingoniothalamin results in increased phosphorylation of and results in increased expression of TP53 protein21810437
C103280goniothalaminpifithrin inhibits the reaction [goniothalamin results in increased phosphorylation of and results in increased expression of TP53 protein]21810437
C103280goniothalaminTP53 mutant form inhibits the reaction [goniothalamin results in increased cleavage of PARP1 protein]21810437
C103280goniothalaminTP53 mutant form inhibits the reaction [goniothalamin results in increased expression of PMAIP1 mRNA]21810437
C103280goniothalaminTP53 mutant form inhibits the reaction [goniothalamin results in increased expression of PMAIP1 protein]21810437
D017273GoserelinGoserelin results in decreased expression of TP53 protein16973256
C511402Grape Seed ProanthocyanidinsGrape Seed Proanthocyanidins affects the expression of TP5312587719
C412815GW 4064GW 4064 results in decreased expression of TP53 mRNA28496032
C412815GW 4064GW 4064 results in decreased expression of TP53 protein28496032
C120727gyrophoric acidgyrophoric acid results in decreased expression of TP53 protein22285236
D055768Halogenated Diphenyl EthersHalogenated Diphenyl Ethers results in decreased expression of TP53 mRNA26808241
D006220HaloperidolHaloperidol results in increased expression of TP53 mRNA16462815
D006220HaloperidolHaloperidol results in increased expression of TP53 protein16462815
C007904harmalolharmalol results in increased expression of TP53 mRNA27590872
C007904harmalolharmalol results in increased expression of TP53 protein27590872
D015386Hazardous SubstancesHazardous Substances results in increased mutagenesis of TP53 exon21550362
C042349heminordihydroguaiaretic acidheminordihydroguaiaretic acid results in increased stability of and results in increased expression of TP53 protein17393435
D006493HeparinHeparin analog results in decreased expression of TP53 protein20201787
D006533HeptachlorHeptachlor results in decreased expression of TP53 protein9544696
C013015hesperetinhesperetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein]15795422
D006575Heterocyclic Compounds, 3-Ring"Heterocyclic Compounds, 3-Ring results in increased expression of TP53 protein"21500194
C089796hexabromocyclododecanehexabromocyclododecane results in increased expression of TP53 mRNA19356805
C089796hexabromocyclododecanehexabromocyclododecane results in decreased expression of TP53 protein24960055
C089796hexabromocyclododecanehexabromocyclododecane results in increased expression of TP53 protein24960055
C089796hexabromocyclododecanehexabromocyclododecane results in increased expression of TP53 mRNA24780359
C089796hexabromocyclododecanehexabromocyclododecane results in increased expression of TP53 protein24780359
C089796hexabromocyclododecanehexabromocyclododecane results in increased expression of TP53 mRNA27718427
C070164homocastasteronehomocastasterone results in increased expression of TP53 protein20833159
D017313FenretinideFenretinide affects the expression of TP5316720286
D017313FenretinideFenretinide results in decreased expression of TP53 mRNA7811993
D017313FenretinideFenretinide results in increased expression of TP53 mRNA17216584
D017313FenretinideFenretinide results in increased expression of TP53 protein16540676|1657028
C012351HT-2 toxinBentonite inhibits the reaction [[HT-2 toxin co-treated with T-2 Toxin] results in increased expression of TP53 mRNA]25296281
C012351HT-2 toxin[HT-2 toxin co-treated with T-2 Toxin] results in increased expression of TP53 mRNA25296281
D006812Humic SubstancesHumic Substances results in increased expression of TP53 protein18683188
D006812Humic SubstancesHumic Substances results in increased phosphorylation of TP53 protein18683188
C050426huperzine Ahuperzine A affects the expression of TP5315956816
D006830Hydralazine[Hydralazine co-treated with Valproic Acid] results in increased expression of TP53 mRNA17183730
D006830HydralazineHydralazine results in increased activity of TP53 protein12082016
D006835HydrazonesHydrazones results in increased expression of and results in increased phosphorylation of TP53 protein22056764
D006861Hydrogen Peroxide2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Hydrogen Peroxide promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]]24933654
D006861Hydrogen Peroxide2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of TP53 protein]]24933654
D006861Hydrogen PeroxideAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]9535218
D006861Hydrogen PeroxideAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]9535218
D006861Hydrogen PeroxideCadmium Chloride inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased activity of TP53 protein]10531375
D006861Hydrogen PeroxideCadmium inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased activity of TP53 protein]10531375
D006861Hydrogen Peroxideepigallocatechin gallate inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein]15795422
D006861Hydrogen PeroxideESRRA protein inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]24967384
D006861Hydrogen PeroxideEUK-134 inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]25005833
D006861Hydrogen Peroxidehesperetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein]15795422
D006861Hydrogen PeroxideHIF1A protein affects the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]25108166
D006861Hydrogen Peroxide"Hydrogen Peroxide inhibits the reaction [N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in decreased expression of TP53 protein]"25005833
D006861Hydrogen PeroxideHydrogen Peroxide inhibits the reaction [SIRT1 protein results in decreased acetylation of TP53 protein]24451382
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [MAPT results in increased expression of TP53 protein]28526263
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]24933654
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [TP53 protein binds to HMOX1 promoter]21552291
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [TP53 protein binds to MDM2 promoter]21552291
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [TP53 protein results in increased expression of BAX]21552291
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [TP53 protein results in increased expression of HMOX1 mRNA]21552291
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [TP53 protein results in increased expression of HMOX1 protein]21552291
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [TP53 protein results in increased expression of MDM2]21552291
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of TP53 mRNA12419474
D006861Hydrogen PeroxideHydrogen Peroxide results in increased acetylation of TP53 protein18681908
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of TP53 protein15242773
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of and results in increased activity of TP53 protein10531375
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of and results in increased phosphorylation of TP53 protein29110037
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of TP5321552291
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of TP53 mRNA27049278|9535218
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of TP53 protein11964141|1508187
D006861Hydrogen Peroxide[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of BAX protein15081873
D006861Hydrogen Peroxide[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein15081873
D006861Hydrogen Peroxide[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein15081873
D006861Hydrogen PeroxideHydrogen Peroxide results in increased glutathionylation of TP53 protein17555331
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein15795422
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of TP5321552291
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of TP53 protein24933654
D006861Hydrogen Peroxidemyricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]23639522
D006861Hydrogen Peroxidenaringenin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein]15795422
D006861Hydrogen Peroxide[Niacinamide results in decreased activity of SIRT1 protein] promotes the reaction [Hydrogen Peroxide results in increased acetylation of TP53 protein]18681908
D006861Hydrogen PeroxidePergolide inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]15081873
D006861Hydrogen PeroxidePergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of BAX protein]15081873
D006861Hydrogen PeroxidePergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein]15081873
D006861Hydrogen PeroxidePergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein]15081873
D006861Hydrogen PeroxideQuercetin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]25108166
D006861Hydrogen PeroxideQuercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein]15795422
D006861Hydrogen Peroxideresveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]27049278
D006861Hydrogen Peroxideresveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]23859249
D006861Hydrogen Peroxideresveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of TP53 protein]24933654
D006861Hydrogen Peroxide[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [Hydrogen Peroxide results in increased acetylation of TP53 protein]18681908
D006861Hydrogen PeroxideSIRT1 protein inhibits the reaction [Hydrogen Peroxide results in increased acetylation of TP53 protein]18681908
D006861Hydrogen Peroxide[sirtinol results in decreased activity of SIRT1 protein] promotes the reaction [Hydrogen Peroxide results in increased acetylation of TP53 protein]18681908
D006861Hydrogen PeroxideSN50 peptide inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]15081873
D006861Hydrogen PeroxideSN50 peptide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of BAX protein]15081873
D006861Hydrogen PeroxideSN50 peptide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein]15081873
D006861Hydrogen PeroxideSN50 peptide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein]15081873
D006861Hydrogen PeroxideTP53 affects the reaction [Hydrogen Peroxide results in increased expression of CDKN1A mRNA]24067374
D006861Hydrogen PeroxideTP53 affects the reaction [Hydrogen Peroxide results in increased expression of TPT1 mRNA]24067374
D006861Hydrogen PeroxideTP53 protein affects the reaction [Hydrogen Peroxide results in increased expression of CDKN1A mRNA]8943236
D006861Hydrogen PeroxideTP53 protein results in decreased susceptibility to Hydrogen Peroxide21552291|2406737
D006861Hydrogen PeroxideTP53 protein results in increased susceptibility to Hydrogen Peroxide17301063
D006861Hydrogen Peroxide"2-(4-((dimethylamino)methyl)benzylidene)-5,6-dimethoxy-2,3-dihydroinden-1-one inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]"19345205
D006861Hydrogen Peroxidedonepezil inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]19345205
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of and affects the localization of TP53 protein14689451
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of TP53 mRNA12414117|1468945
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of TP53 protein12414117|1264240
D006861Hydrogen PeroxideLuteolin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]27525270
D006861Hydrogen PeroxideMelatonin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]20041988
D006861Hydrogen PeroxideQuercetin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]16647178|2752527
D006861Hydrogen PeroxideTacrine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]12414117
D006861Hydrogen PeroxideTacrine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]12414117
D006861Hydrogen PeroxideTacrolimus inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]12642403
D006861Hydrogen PeroxideV 10367 inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]12642403
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein18608517
C031927hydroquinonehydroquinone results in decreased expression of TP53 mRNA26047893
C031927hydroquinonehydroquinone results in increased expression of TP53 protein17875398
C031927hydroquinone[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of TP53 protein28444915
C031927hydroquinoneWRN protein affects the reaction [hydroquinone results in increased acetylation of TP53 protein]17875398
C031927hydroquinoneWRN protein affects the reaction [hydroquinone results in increased expression of TP53 protein]17875398
D006877Hydroxamic AcidsHydroxamic Acids analog results in increased acetylation of TP53 protein19084294
D006881HydroxyacetylaminofluoreneHydroxyacetylaminofluorene results in increased expression of TP53 protein9163691
D0201553-Hydroxybutyric Acid3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in increased acetylation of TP53 protein]25440059
D004441EcdysteroneEcdysterone results in increased expression of TP53 mRNA15776001
D003900Desoxycorticosteroneacetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]22431579
D003900Desoxycorticosteroneatrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]22431579
D003900Desoxycorticosterone[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein22431579
D006918HydroxyureaHydroxyurea results in increased expression of TP53 protein10978678|1600571
D006918HydroxyureaHydroxyurea results in increased expression of TP53 protein modified form25125662
C559745hyperforin dicyclohexylammoniumhyperforin dicyclohexylammonium results in increased expression of TP53 protein21376709
C000623387HZ-6d compoundHZ-6d compound results in increased expression of TP53 protein28919514
D007052IbuprofenIbuprofen affects the activity of TP53 protein25596134
C411652IC 261IC 261 affects the expression of TP53 protein16027726
D007069IfosfamideIfosfamide affects the activity of TP53 protein25596134
D007213IndomethacinIndomethacin results in increased expression of TP53 protein10403534|1126086
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TP53 mRNA25613284
C033148iprodione[iprodione co-treated with acetamiprid] results in decreased expression of TP53 mRNA29091792
C033148iprodione[iprodione co-treated with pyrachlostrobin] results in decreased expression of TP53 mRNA29091792
C033148iprodione[iprodione co-treated with pyrimethanil co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C033148iprodione[iprodione co-treated with pyrimethanil co-treated with pyrachlostrobin co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C033148iprodione[iprodione co-treated with pyrimethanil co-treated with pyrachlostrobin] results in increased expression of TP53 mRNA29091792
C033148iprodione[iprodione co-treated with pyrimethanil] results in decreased expression of TP53 mRNA29091792
C033148iprodioneiprodione results in decreased expression of TP53 mRNA29091792
C051890irinotecan[irinotecan co-treated with Bortezomib] results in increased ubiquitination of TP53 protein16373703
C051890irinotecanirinotecan results in increased expression of TP53 mRNA22898888
C051890irinotecanirinotecan results in increased expression of TP53 protein16963839|2251056
C051890irinotecanirinotecan results in increased phosphorylation of and results in increased activity of TP53 protein16963839
C051890irinotecanirinotecan results in increased phosphorylation of and results in increased expression of TP53 protein22898888
C051890irinotecanirinotecan results in increased phosphorylation of TP53 protein22510560
C051890irinotecanTP53 protein affects the susceptibility to irinotecan16963839
C051890irinotecanTP53 protein affects the susceptibility to [irinotecan co-treated with Bortezomib]16373703
C051890irinotecanTP53 protein inhibits the reaction [irinotecan results in increased phosphorylation of STAT1 protein]16204068
C051890irinotecanTP53 results in increased susceptibility to irinotecan22898888
D007501IronIron results in increased expression of TP53 protein16957011
D058085Iron CompoundsIron Compounds results in increased expression of TP53 protein28483490
D058085Iron CompoundsIron Compounds results in increased expression of TP53 protein modified form28483490
D007510Isatin[Copper binds to Isatin binds to 2-(2-aminoethyl)pyridine] which results in increased expression of TP53 protein17327230
D007510Isatin[Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of TP53 protein17327230
D007510IsatinTretinoin inhibits the reaction [[Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of TP53 protein]17327230
D017953IsocyanatesIsocyanates results in increased expression of TP53 protein19283680
D007529Isoflavones[Folic Acid co-treated with Isoflavones] results in decreased expression of TP53 protein20060418
D007530IsofluraneIsoflurane results in decreased expression of TP53 mRNA16978161
C550177isoliquiritigenin 2'-methyl etherisoliquiritigenin 2'-methyl ether results in increased expression of TP53 protein20040371
D007545IsoproterenolIsoproterenol results in decreased expression of TP53 mRNA24286936
D007545IsoproterenolIsoproterenol results in increased expression of TP53 mRNA24286936
D007545IsoproterenolIsoproterenol results in increased expression of TP53 protein19466570
D007559IvermectinIvermectin inhibits the reaction [geranylgeranic acid affects the localization of TP53 protein mutant form]24658405
C561695(+)-JQ1 compound(+)-JQ1 compound promotes the reaction [tetraarsenic tetrasulfide results in increased expression of TP53 protein]26586936
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased acetylation of TP53 protein26212199
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of TP53 protein26586936
C561695(+)-JQ1 compoundtetraarsenic tetrasulfide promotes the reaction [(+)-JQ1 compound results in increased expression of TP53 protein]26586936
C561695(+)-JQ1 compoundTP53 gene mutant form results in decreased susceptibility to (+)-JQ1 compound24231268
C006552kaempferolCaffeine inhibits the reaction [kaempferol results in increased phosphorylation of TP53 protein]19028473
C006552kaempferolkaempferol results in increased expression of TP53 protein19028473
C006552kaempferolkaempferol results in increased phosphorylation of TP53 protein19028473
C006552kaempferolTP53 protein affects the reaction [kaempferol promotes the reaction [BBC3 protein binds to BCL2L1 protein]]19028473
C006552kaempferolTP53 protein affects the susceptibility to kaempferol19028473
C006552kaempferolkaempferol inhibits the reaction [Doxorubicin promotes the reaction [TP53 protein binds to BAX promoter]]22155320
C006552kaempferolkaempferol inhibits the reaction [Doxorubicin results in increased expression of TP53 mRNA]22155320
C524169kaempferol 7-O-glucosidekaempferol 7-O-glucoside affects the expression of TP53 protein18343026
D007608Kainic AcidKainic Acid results in increased expression of TP53 protein20955365
D007649KetamineKetamine results in increased expression of TP53 mRNA28716577
D007649KetamineKetamine results in increased expression of TP53 protein19919587
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA18544905
C045492kolavironkolaviron inhibits the reaction [Atrazine results in decreased expression of TP53 mRNA]21333729
C045492kolavironkolaviron inhibits the reaction [Atrazine results in decreased expression of TP53 protein]21333729
C045492kolavironkolaviron inhibits the reaction [Atrazine affects the expression of TP53]21726175
C067713lactacystinlactacystin inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]16330492
C067713lactacystinlactacystin results in increased phosphorylation of and results in increased expression of TP53 protein18463101
C067713lactacystinlactacystin results in increased ubiquitination of TP53 protein18463101
C060347lanreotidelanreotide inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 mRNA]19874807
D064747LansoprazoleLansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of TP53 mRNA]28412091
D007854Lead[Lead co-treated with APP protein modified form] results in increased expression of TP53 protein22610977
D007854LeadLead results in decreased expression of TP53 mRNA19921347
D007854LeadLead results in increased expression of TP53 protein22610977
C038753leptomycin B"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [leptomycin B results in increased expression of TP53 protein]"19751709
C038753leptomycin Bleptomycin B affects the localization of and results in decreased degradation of TP53 protein24792400
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of BRCA1 mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of CHEK2 mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of DNMT1 mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of HK2 mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of MDM4 mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of PRKCA mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of TP63 mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in increased expression of APAF1 mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in increased expression of BIRC5 mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in increased expression of IL6 mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in increased expression of NFKB1 mRNA20803015
C038753leptomycin B[leptomycin B co-treated with TP53 gene mutant form] results in increased expression of TNFRSF10D mRNA20803015
C038753leptomycin Bleptomycin B inhibits the reaction [sodium arsenite affects the localization of TP53 protein]19010883
C038753leptomycin Bleptomycin B inhibits the reaction [sodium arsenite results in increased degradation of TP53 protein mutant form]21454520
C038753leptomycin Bleptomycin B inhibits the reaction [TP53 protein results in increased susceptibility to trichostatin A]16467109
C038753leptomycin Bleptomycin B results in decreased degradation of TP53 protein15625077
C038753leptomycin Bleptomycin B results in increased expression of TP53 protein16467109|1975170
C038753leptomycin BPCB 180 promotes the reaction [leptomycin B results in increased expression of TP53 protein]19751709
C038753leptomycin BPravastatin inhibits the reaction [leptomycin B results in decreased degradation of TP53 protein]15625077
C038753leptomycin B[sodium arsenite co-treated with leptomycin B] results in increased phosphorylation of TP53 protein19010883
C038753leptomycin BTP53 gene mutant form inhibits the reaction [leptomycin B results in decreased expression of BIRC5 protein]20803015
C038753leptomycin BTP53 gene mutant form inhibits the reaction [leptomycin B results in increased expression of CDKN1A protein]20803015
C038753leptomycin BTP53 gene mutant form results in increased susceptibility to leptomycin B20803015
C038753leptomycin Balpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [leptomycin B results in increased expression of TP53 protein]]15459018
C038753leptomycin Bleptomycin B affects the expression of TP53 protein11751435
C038753leptomycin Bleptomycin B results in increased expression of TP53 protein15459018
C038753leptomycin BTetrachlorodibenzodioxin inhibits the reaction [leptomycin B results in increased expression of TP53 protein]15459018
C008281limonenelimonene results in increased expression of TP53 protein12921557
C018584linaloollinalool results in increased expression of TP53 mRNA26703569
C018584linaloollinalool results in increased expression of TP53 protein19922762
C018584linaloolTP53 results in increased susceptibility to linalool19922762
D001556Lindane[Lindane co-treated with Estradiol] results in increased expression of TP53 protein18174961
D044243Linoleic Acids, Conjugated"Linoleic Acids, Conjugated results in increased expression of TP53 protein"15961301
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of TP53 mRNA9409811
D008070LipopolysaccharidesLipopolysaccharides results in increased localization of TP53 protein12665479
D008070Lipopolysaccharidespifithrin inhibits the reaction [Lipopolysaccharides results in increased localization of TP53 protein]12665479
C506643liposomal doxorubicinliposomal doxorubicin results in increased phosphorylation of TP53 protein27923599
D008094LithiumLithium results in increased expression of TP53 protein11337498
D008094LithiumLithium inhibits the reaction [GSK3B protein binds to TP53 protein]15475000
D008094LithiumLithium inhibits the reaction [sodium arsenite results in increased expression of and affects the localization of TP53 protein]17849503
D008094LithiumTP53 affects the reaction [Lithium results in increased expression of CDKN1A protein]11337498
D018021Lithium ChlorideTP53 protein promotes the reaction [Lithium Chloride results in increased expression of MMP1 mRNA]19407340
D018021Lithium ChlorideLithium Chloride results in increased expression of TP53 protein17210701
C558899lopinavir-ritonavir drug combinationFTI 277 inhibits the reaction [lopinavir-ritonavir drug combination results in increased expression of TP53 protein]20884875
C558899lopinavir-ritonavir drug combinationlopinavir-ritonavir drug combination results in increased expression of TP53 protein20884875
C558899lopinavir-ritonavir drug combinationmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [lopinavir-ritonavir drug combination results in increased expression of TP53 protein]20884875
C558899lopinavir-ritonavir drug combinationPravastatin inhibits the reaction [lopinavir-ritonavir drug combination results in increased expression of TP53 protein]20884875
D019808LosartanLosartan affects the expression of TP53 protein22000973
D008148LovastatinLovastatin inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]17088865
D008148LovastatinLovastatin results in increased expression of and results in increased phosphorylation of TP53 protein21199873
D008148LovastatinLovastatin results in increased expression of TP53 mRNA21199873
D008148LovastatinLovastatin inhibits the reaction [Cisplatin results in increased expression of TP53 protein modified form]26739623
C010480lupeollupeol inhibits the reaction [mancozeb results in increased expression of TP53 mRNA]27235710
D047311LuteolinLuteolin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]27525270
C015329lycopenelycopene results in decreased expression of TP53 mRNA16886892
D015636Magnesium ChlorideMagnesium Chloride affects the expression of TP53 mRNA10506531
D008277Magnesium OxideMagnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of TP53 mRNA]27920530
D008277Magnesium Oxide[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of TP53 mRNA]27920530
D058185Magnetite Nanoparticles[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of TP53 mRNA24738333
D058185Magnetite Nanoparticles[arsenic trioxide co-treated with Doxorubicin co-treated with Magnetite Nanoparticles analog] affects the expression of TP53 protein24738333
D058185Magnetite Nanoparticles[Daunorubicin co-treated with Magnetite Nanoparticles] results in increased activity of TP53 protein21518493
C005095malachite greenmalachite green results in increased expression of TP53 protein10840942
D008294MalathionAtropine inhibits the reaction [Malathion results in increased expression of TP53 protein]12762645
D008294MalathionMalathion results in increased expression of TP53 mRNA18204794
D008294MalathionMalathion results in increased expression of TP53 protein12762645|1978726
D008294MalathionMalathion results in increased expression of TP53 mRNA21628957
D008294Malathion[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 mRNA]21628957
C043592maleimidemaleimide analog binds to and results in increased activity of TP53 protein mutant form15998635
C013099mancozeblupeol inhibits the reaction [mancozeb results in increased expression of TP53 mRNA]27235710
C013099mancozebmancozeb results in increased expression of TP53 mRNA27235710
D008345ManganeseManganese results in increased expression of TP53 protein18284614|2018875
D008345ManganeseKHSRP protein affects the reaction [Manganese results in increased expression of TP53 protein]25027559
D008345Manganese[Manganese co-treated with NGF protein] results in increased expression of and affects the localization of TP53 protein25448048
D008345Manganese[Manganese co-treated with NGF protein] results in increased phosphorylation of and results in increased expression of TP53 protein25791630
D008345ManganeseManganese results in increased expression of TP53 mRNA23997110
D008345ManganeseManganese results in increased expression of TP53 protein24845367|2502755
D008345ManganeseManganese results in increased phosphorylation of and results in increased expression of TP53 protein25791630
D008345ManganesePPM1D mutant form promotes the reaction [[Manganese co-treated with NGF protein] results in increased phosphorylation of TP53 protein]25791630
D008345ManganesePPM1D protein inhibits the reaction [[Manganese co-treated with NGF protein] results in increased phosphorylation of TP53 protein]25791630
D008345ManganeseTP53 protein results in increased susceptibility to Manganese25791630
C025340manganese chloridemanganese chloride results in increased expression of TP53 mRNA17623882
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [lopinavir-ritonavir drug combination results in increased expression of TP53 protein]20884875
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Ritonavir results in increased expression of TP53 protein]20884875
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [IL1B protein results in increased expression of TP53 protein]12384474
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin results in increased expression of TP53 protein12384474
C520506manganese tetrakis-(N-ethyl-2 pyridyl) porphyrinmanganese tetrakis-(N-ethyl-2 pyridyl) porphyrin results in decreased activity of TP5320454814
C013592mangiferinmangiferin inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]10657591
C021053mangostinmangostin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TP53 mRNA]26357513
C021053mangostinmangostin results in increased expression of TP53 protein24480042
C021053mangostinmangostin inhibits the reaction [Cisplatin results in increased expression of TP53]20603111
D009637MasoprocolMasoprocol results in increased expression of TP53 protein15034932
D009637MasoprocolMYC affects the reaction [Masoprocol results in increased expression of TP53 protein]15034932
C034244matrinematrine results in increased expression of TP53 mRNA11489473
D008466MechlorethamineMechlorethamine results in increased expression of TP53 protein16738803
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of TP53 protein22534328
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of TP53 protein22534328
D017258Medroxyprogesterone Acetate"[Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate] results in decreased expression of TP53 protein"16021059
D008550MelatoninMelatonin inhibits the reaction [Cisplatin results in increased phosphorylation of and results in increased expression of TP53 protein]24799992
D008550MelatoninMelatonin results in increased expression of TP53 protein12071473|1901266
D008550MelatoninMelatonin inhibits the reaction [bisphenol A results in increased expression of TP53 protein]25454643
D008550MelatoninMelatonin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]20041988
D008550MelatoninMelatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]14993511
D008687MetforminMetformin affects the activity of TP53 protein25596134
D008701MethapyrileneMethapyrilene results in increased expression of TP53 mRNA26558467
C054938methoctraminemethoctramine analog results in increased expression of TP53 protein19576191
D008727Methotrexate[Methotrexate results in decreased susceptibility to Methotrexate] inhibits the reaction [Mitomycin results in increased expression of TP53 protein mutant form]16598767
D008727Methotrexate[Methotrexate results in decreased susceptibility to Methotrexate] which affects the localization of and results in decreased activity of TP53 protein mutant form16598767
D008727MethotrexateAcetylcysteine inhibits the reaction [Methotrexate results in increased expression of TP53 mRNA]22183962
D008727MethotrexateAcetylcysteine inhibits the reaction [Methotrexate results in increased expression of TP53 protein]24967384
D008727MethotrexateBRCA1 mutant form promotes the reaction [TP53 mutant form results in increased susceptibility to Methotrexate]21875941
D008727MethotrexateESRRA protein inhibits the reaction [Methotrexate results in increased expression of TP53 protein]24967384
D008727MethotrexateFolic Acid inhibits the reaction [Methotrexate results in increased expression of TP53 mRNA]22183962
D008727MethotrexateMAPK9 gene mutant form inhibits the reaction [Methotrexate results in increased expression of TP53 protein]22183962
D008727MethotrexateMethotrexate inhibits the reaction [TP53 protein results in increased expression of CDKN1A protein]19548002
D008727MethotrexateMethotrexate results in decreased expression of TP53 mRNA17400583|2444957
D008727MethotrexateMethotrexate results in increased expression of TP53 mRNA21678067|2218396
D008727MethotrexateMethotrexate results in increased expression of TP53 protein21624110|2218396
D008727MethotrexateMethotrexate results in increased phosphorylation of and results in increased acetylation of and results in increased stability of TP53 protein21114963
D008727Methotrexatenutlin 3 promotes the reaction [Methotrexate results in increased expression of TP53 protein]21624110
D008727Methotrexatesapropterin inhibits the reaction [Methotrexate results in increased expression of TP53 protein]22183962
D008727MethotrexateTP53 affects the reaction [Methotrexate results in increased activity of and results in increased expression of CDKN1A protein]21624110
D008727MethotrexateTP53 affects the reaction [Methotrexate results in increased activity of and results in increased expression of MDM2 protein]21624110
D008727MethotrexateTP53 affects the reaction [nutlin 3 promotes the reaction [Methotrexate results in increased activity of and results in increased expression of CDKN1A protein]]21624110
D008727MethotrexateTP53 affects the reaction [nutlin 3 promotes the reaction [Methotrexate results in increased activity of and results in increased expression of MDM2 protein]]21624110
D008727MethotrexateTP53 mutant form results in increased susceptibility to Methotrexate21875941
D008727MethotrexateTP53 protein inhibits the reaction [Methotrexate results in increased expression of CCNB1 protein]19548002
D008727MethotrexateTP53 protein promotes the reaction [Methotrexate results in increased expression of CASP8 mRNA]17637740
D008727MethotrexateTP53 protein promotes the reaction [Methotrexate results in increased expression of CASP8 protein]17637740|2201021
D008727MethotrexateTP53 protein promotes the reaction [Methotrexate results in increased expression of CDKN1A protein]21114963
D008727MethotrexateTP53 protein promotes the reaction [Methotrexate results in increased susceptibility to Antineoplastic Agents]22010212
D008727MethotrexateTP53 protein promotes the reaction [Methotrexate results in increased susceptibility to Cyclophosphamide metabolite]22010212
D008727MethotrexateTP53 protein results in increased susceptibility to Methotrexate19548002
D008727MethotrexateMethotrexate results in increased expression of TP53 protein19900424
D008727MethotrexateThioctic Acid inhibits the reaction [Methotrexate results in increased expression of TP53 protein]19900424
C013598methoxyacetic acid"6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide inhibits the reaction [methoxyacetic acid results in increased expression of TP53 protein]"21573189
C013598methoxyacetic acidmethoxyacetic acid results in increased expression of TP53 protein21573189
D008730MethoxsalenMethoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of TP53 protein modified form]23907605
D008730MethoxsalenMethoxsalen results in increased expression of TP53 protein22796345
C587228methyl 3-hydroxyimino-11-oxoolean-12-en-28-oatemethyl 3-hydroxyimino-11-oxoolean-12-en-28-oate affects the localization of TP53 protein24291674
C042405methyl caffeatemethyl caffeate analog results in increased expression of TP53 protein25481497
C005219methyl cellosolvemethyl cellosolve results in increased expression of TP53 mRNA19643169
D008748MethylcholanthreneMethylcholanthrene results in increased expression of TP53 mRNA23273579
C005223methyleugenolmethyleugenol results in decreased expression of TP53 mRNA26011634
C005223methyleugenolmethyleugenol results in increased expression of TP53 protein23411599
C000614724methyleugenol-2',3'-epoxide"methyleugenol-2',3'-epoxide results in increased phosphorylation of TP53 protein"28818686
D012862SkatoleSkatole results in increased phosphorylation of and affects the localization of TP53 protein19700606
C008461methyl isocyanatemethyl isocyanate affects the expression of TP53 protein19513903
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of TP53 mRNA23458150
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of TP53 protein20153410
D008741Methyl MethanesulfonateCadmium Chloride inhibits the reaction [Methyl Methanesulfonate results in increased expression of and results in increased activity of TP53 protein]10531375
D008741Methyl MethanesulfonateCadmium inhibits the reaction [Methyl Methanesulfonate results in increased expression of and results in increased activity of TP53 protein]10531375
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased activity of TP53 protein20655369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of and results in increased activity of TP53 protein10531375
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased phosphorylation of and results in increased activity of TP53 protein25078064
D008741Methyl MethanesulfonateTP53 gene mutant form results in increased susceptibility to Methyl Methanesulfonate25595616
D008741Methyl MethanesulfonateTP53 protein affects the reaction [Methyl Methanesulfonate results in increased expression of CDKN1A mRNA]17079232
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased expression of TP53 mRNA12634122
D008769MethylnitronitrosoguanidineTP53 protein mutant form results in decreased susceptibility to Methylnitronitrosoguanidine15589979
D008769MethylnitronitrosoguanidineTP53 protein results in increased susceptibility to Methylnitronitrosoguanidine15589979
D008769MethylnitronitrosoguanidineEugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TP53 protein]19851710
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in decreased expression of TP53 protein19851710
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased acetylation of TP53 protein17147953
D008769Methylnitronitrosoguanidineresveratrol inhibits the reaction [Methylnitronitrosoguanidine results in increased acetylation of TP53 protein]17147953
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of and results in increased phosphorylation of TP53 protein29110037
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of TP53 mRNA20965277
D008770MethylnitrosoureaButylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TP53 protein]18593901
D008770Methylnitrosourea[Estradiol co-treated with Methylnitrosourea co-treated with Progesterone] results in decreased expression of TP53 mRNA20732338
D008770Methylnitrosourea[Methylnitrosourea co-treated with Progesterone] results in decreased expression of TP53 mRNA20732338
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of TP53 mRNA17412507|2868890
D008770MethylnitrosoureaMethylnitrosourea results in increased phosphorylation of TP53 protein18593901
C008480methylparaoxonmethylparaoxon results in increased expression of TP53 mRNA18418871
D008743Methyl ParathionMethyl Parathion results in increased expression of TP53 mRNA18418871
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of TP53 mRNA24810058
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of TP53 mRNA26357513
D0156551-Methyl-4-phenylpyridiniummangostin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TP53 mRNA]26357513
D0156551-Methyl-4-phenylpyridiniumU 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of TP53 mRNA]12710931
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased acetylation of TP53 protein17583434
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of TP53 protein26677001
D015741Metribolone[Curcumin co-treated with Metribolone] results in increased phosphorylation of TP53 protein21134073
D015741MetriboloneTP53 protein inhibits the reaction [Metribolone results in increased expression of NKX3-1 mRNA]17202838
C574930MI-219MI-219 results in decreased activity of [MDM2 protein binds to TP53 protein]21314128
C063855microcystin RRmicrocystin RR results in increased expression of TP53 protein19111056
D052998MicrocystinsMicrocystins results in increased expression of TP53 mRNA19760617
D052998MicrocystinsMicrocystins results in increased expression of TP53 protein19760617
C059539midostaurinmidostaurin affects the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]15542774
C059539midostaurinmidostaurin inhibits the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]]15542774
D008911MinocyclineMinocycline results in decreased expression of TP53 protein15172883
C066851mithramycin Amithramycin A inhibits the reaction [[TP53 protein binds to SP1 protein] which results in increased expression of BBC3 mRNA]15489892
C066851mithramycin Amithramycin A inhibits the reaction [[TP53 protein binds to SP1 protein] which results in increased expression of CDKN1A mRNA]15489892
C066851mithramycin Amithramycin A results in increased activity of TP53 protein17124180
C066851mithramycin Amithramycin A results in increased phosphorylation of TP53 protein15489892
D016685Mitomycin[Methotrexate results in decreased susceptibility to Methotrexate] inhibits the reaction [Mitomycin results in increased expression of TP53 protein mutant form]16598767
D016685MitomycinMitomycin results in increased expression of TP53 protein16598767
D016685MitomycinMitomycin results in increased expression of TP53 protein mutant form16598767
D016685MitomycinMitomycin promotes the reaction [TP53 protein results in increased expression of CCNB1 mRNA]18647660
D016685MitomycinMitomycin promotes the reaction [TP53 protein results in increased expression of CDKN1A mRNA]18647660
D016685MitomycinMitomycin promotes the reaction [TP53 protein results in increased expression of DDB2 mRNA]18647660
D016685MitomycinMitomycin promotes the reaction [TP53 protein results in increased expression of GADD45A mRNA]18647660
D016685MitomycinMitomycin promotes the reaction [TP53 protein results in increased expression of HSPA8 mRNA]18647660
D016685MitomycinMitomycin promotes the reaction [TP53 protein results in increased expression of PCNA mRNA]18647660
D016685MitomycinMitomycin promotes the reaction [TP53 protein results in increased expression of SGK1 mRNA]18647660
D016685MitomycinMitomycin promotes the reaction [TP53 protein results in increased expression of TP53I3 mRNA]18647660
D016685MitomycinMitomycin promotes the reaction [TP53 protein results in increased expression of TRIAP1 mRNA]18647660
D016685MitomycinMitomycin results in increased expression of TP5319834285
D016685MitomycinMitomycin results in increased expression of TP53 mRNA18647660
D016685MitomycinMitomycin results in increased expression of TP53 protein12082016|2467508
D016685MitomycinMitomycin results in increased expression of TP53 protein modified form16186332
D016685MitomycinMitomycin results in increased phosphorylation of and results in increased activity of TP53 protein24675086
D016685MitomycinMitomycin results in increased stability of TP53 protein20536192
D016685Mitomycin[Mitomycin results in increased stability of TP53 protein] which results in increased expression of CDKN1A mRNA20536192
D016685Mitomycin[Mitomycin results in increased stability of TP53 protein] which results in increased expression of MDM2 mRNA20536192
D016685Mitomycinsilybin inhibits the reaction [Mitomycin results in increased expression of TP53]19834285
D016685MitomycinTP53 protein affects the susceptibility to Mitomycin15182437|2000047
C019215mitonafidemitonafide analog results in increased expression of TP53 protein19954251
C549567MK-1775TP53 gene mutant form results in increased susceptibility to MK-177525125259
D008982MolybdenumMolybdenum analog results in increased expression of and results in increased phosphorylation of TP53 protein26391003
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased activity of TP53 protein21515331
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased phosphorylation of and results in increased expression of TP53 protein24706461
C016599mono-(2-ethylhexyl)phthalateSelenomethionine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of TP53 protein]21515331
C016599mono-(2-ethylhexyl)phthalateSodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of TP53 protein]21515331
C016599mono-(2-ethylhexyl)phthalateTP53 protein results in decreased susceptibility to mono-(2-ethylhexyl)phthalate24706461
D008999MonocrotophosMonocrotophos results in increased expression of TP53 mRNA20957986
D008999MonocrotophosMonocrotophos results in increased expression of TP53 protein20957986
C091888monoisoamyl-2,3-dimercaptosuccinate"monoisoamyl-2,3-dimercaptosuccinate results in increased expression of TP53 mRNA"19615344
C020300monomethylarsonic acid[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TP53 mRNA23192986
C406082monomethylarsonous acid"monomethylarsonous acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of and results in increased phosphorylation of and results in increased localization of and results in increased activity of TP53 protein]"18085531
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased expression of TP53 mRNA22108045
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of TP53 protein19382146
C406082monomethylarsonous acidTP53 protein results in increased susceptibility to monomethylarsonous acid18085531
C041105monomethyl succinate"monomethyl succinate inhibits the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
C008548morinmorin results in increased expression of TP53 mRNA28689916
D009020MorphineMorphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]12927789
D009020MorphineMorphine results in increased expression of TP53 mRNA19397953
D009020MorphineMorphine results in increased phosphorylation of and results in increased activity of TP53 protein19397953
D009020MorphineMorphine results in increased phosphorylation of and results in increased stability of TP53 protein12702572
D009020Morphine[Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of BAX protein12702572
D009020Morphine[Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of CDKN1A protein12702572
D009020Morphine[Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of FAS protein12702572
D009020MorphineNaloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]]12927789
D009020MorphineNaloxone inhibits the reaction [Morphine results in increased expression of TP53]19397953
D009020MorphineNaloxone inhibits the reaction [Morphine results in increased phosphorylation of TP53 protein]19397953
D009020MorphineMorphine results in increased expression of TP53 protein9469450
C437683motexafin gadoliniumAcetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
C437683motexafin gadolinium[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein20530418
C437683motexafin gadoliniumbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
C437683motexafin gadoliniumnutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
C523799MRK 003MRK 003 inhibits the reaction [resveratrol results in increased expression of TP53]21743969
D009150Mustard Compoundscaffeic acid phenethyl ester inhibits the reaction [Mustard Compounds results in increased phosphorylation of TP53 protein]17204746
D009150Mustard CompoundsMustard Compounds results in increased phosphorylation of TP53 protein17204746
D009151Mustard Gas2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Mustard Gas results in increased expression of TP53 protein]22119920
D009151Mustard Gas2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Mustard Gas results in increased phosphorylation of TP53 protein]22119920
D009151Mustard GasMustard Gas results in increased expression of TP53 protein11428642|1974899
D009151Mustard GasMustard Gas results in increased expression of TP53 protein modified form25102026
D009151Mustard GasMustard Gas results in increased phosphorylation of TP53 protein19845377|2014345
D009151Mustard Gaswortmannin inhibits the reaction [Mustard Gas results in increased expression of TP53 protein]22119920
D009151Mustard Gaswortmannin inhibits the reaction [Mustard Gas results in increased phosphorylation of TP53 protein]22119920
D009151Mustard GasMustard Gas results in increased expression of TP53 protein9302645
C008577myricitrinmyricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]23639522
C061545myrtenalmyrtenal inhibits the reaction [[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA]22436021
C061545myrtenalmyrtenal inhibits the reaction [[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 protein]22436021
C514580N1-(2-aminophenyl)-N8-phenyloctanediamideN1-(2-aminophenyl)-N8-phenyloctanediamide affects the expression of TP53 protein17341627
C059685N(1),N(11)-diethylnorspermine"N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of TP53 protein]"15546879
C059685N(1),N(11)-diethylnorspermine"TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]]"15546879
C059685N(1),N(11)-diethylnorspermine"TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]]"15546879
C059685N(1),N(11)-diethylnorspermine"TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of CASP9 protein]]"15546879
C059685N(1),N(11)-diethylnorspermine"TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]]"15546879
C059685N(1),N(11)-diethylnorspermine"TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]]"15546879
C059685N(1),N(11)-diethylnorspermine"TP53 protein promotes the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in increased expression of FAS protein]]"15546879
C059685N(1),N(11)-diethylnorspermine"TP53 protein promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of CDKN1A protein]"15546879
C059685N(1),N(11)-diethylnorspermine"TP53 protein promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]"15546879
C469937N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine"MYC mutant form inhibits the reaction [N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine results in increased expression of TP53 protein]"24444383
C469937N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine"[N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine co-treated with MYC protein] results in increased expression of TP53 protein"24444383
C469937N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine"N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine results in increased expression of TP53 protein"16140939|2444438
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of TP53 mRNA]29242151
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]16928824|2924215
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [Ceramides results in increased phosphorylation of TP53 protein]23495037
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [resveratrol results in increased activity of TP53 protein]18446786
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of TP53 mRNA29242151
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]17984113
C556398N-(2-(dimethylamino)ethyl)-2-aminothiazonaphthalimideN-(2-(dimethylamino)ethyl)-2-aminothiazonaphthalimide promotes the reaction [TP53 protein binds to BCL2 promoter]21821060
C556398N-(2-(dimethylamino)ethyl)-2-aminothiazonaphthalimideN-(2-(dimethylamino)ethyl)-2-aminothiazonaphthalimide results in increased expression of TP53 protein21821060
C556398N-(2-(dimethylamino)ethyl)-2-aminothiazonaphthalimideTP53 mutant form inhibits the reaction [N-(2-(dimethylamino)ethyl)-2-aminothiazonaphthalimide results in decreased expression of BCL2 protein]21821060
C556398N-(2-(dimethylamino)ethyl)-2-aminothiazonaphthalimideTP53 mutant form inhibits the reaction [N-(2-(dimethylamino)ethyl)-2-aminothiazonaphthalimide results in increased expression of CDKN1A protein]21821060
C064769N-acetylsphingosineAcetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of TP53 mRNA]9535218
C064769N-acetylsphingosineAcetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of TP53 protein]9535218
C064769N-acetylsphingosineN-acetylsphingosine results in increased expression of TP53 mRNA9535218
C064769N-acetylsphingosineN-acetylsphingosine results in increased expression of TP53 protein9535218
D009270NaloxoneNaloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]]12927789
D009270NaloxoneNaloxone inhibits the reaction [Morphine results in increased expression of TP53]19397953
D009270NaloxoneNaloxone inhibits the reaction [Morphine results in increased phosphorylation of TP53 protein]19397953
D009270NaloxoneNaloxone results in decreased expression of TP53 mRNA17522070
D019810Sodium AzideSodium Azide inhibits the reaction [2-butylamino-2-demethoxy-hypocrellin B results in increased expression of TP53 mRNA]17045927
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of and results in increased phosphorylation of TP53 protein"23634900
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of TP53 mRNA"15585362
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of TP53 mRNA"26146619
C031721naphthalene"[naphthalene binds to pyrrolo(2,1-c)(1,4)benzodiazepine] which results in increased expression of TP53 protein"21732540
D009281NaphthalenesNaphthalenes results in increased expression of TP53 protein17224139
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of TP53 mRNA17522070
C005273naringeninnaringenin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein]15795422
C005273naringeninnaringenin results in increased expression of and results in increased phosphorylation of TP53 protein27838343
C005274naringinnaringin results in increased expression of TP53 mRNA22847135
C005274naringinnaringin inhibits the reaction [Cisplatin results in increased expression of TP53 mRNA]26120027|2661265
C101954N-caproylsphingosinecalyculin A inhibits the reaction [N-caproylsphingosine affects the splicing of and results in increased expression of TP53 mRNA]25195822
C101954N-caproylsphingosinecalyculin A inhibits the reaction [N-caproylsphingosine results in increased expression of TP53 protein modified form]25195822
C101954N-caproylsphingosineN-caproylsphingosine affects the splicing of and results in increased expression of TP53 mRNA25195822
C101954N-caproylsphingosineN-caproylsphingosine results in increased phosphorylation of TP53 protein25195822
C101954N-caproylsphingosineSRSF1 protein promotes the reaction [N-caproylsphingosine affects the splicing of and results in increased expression of TP53 mRNA]25195822
C101954N-caproylsphingosineSRSF1 protein promotes the reaction [N-caproylsphingosine results in increased expression of TP53 protein modified form]25195822
C066471NCS 382NCS 382 affects the expression of TP53 mRNA28119166
C507699necrostatin-1necrostatin-1 inhibits the reaction [Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein]25939952
C010463n-hexanaln-hexanal results in decreased expression of TP53 mRNA12921975
C014593N-hydroxy-4-aminobiphenyl[N-hydroxy-4-aminobiphenyl co-treated with Copper] results in increased mutagenesis of TP53 gene11275476
D009525NiacinNiacin deficiency affects the expression of TP53 protein17516866
D009525NiacinNiacin deficiency inhibits the reaction [Etoposide results in increased expression of TP53 protein]17516866
D009525NiacinNiacin deficiency results in decreased expression of TP53 mRNA17516866
D009532NickelNickel analog results in increased expression of TP53 protein23776134
D009532NickelNickel results in decreased expression of TP53 mRNA23195993
D009532NickelNickel results in increased expression of and results in increased phosphorylation of TP53 protein24068677
D009532Nickel[Quercetin analog co-treated with Nickel] results in increased expression of TP53 protein20577783
D009532NickelTP53 protein affects the reaction [Nickel results in increased cleavage of and results in increased activity of CASP3 protein]24068677
D009532NickelTP53 protein affects the reaction [Nickel results in increased expression of CDKN1A mRNA]24068677
D009532NickelTP53 protein affects the reaction [Nickel results in increased expression of MDM2 mRNA]24068677
C022838nickel chloridenickel chloride results in decreased activity of TP53 protein25446071
C022838nickel chloride[nickel chloride results in decreased activity of TP53 protein] inhibits the reaction [TP53 protein binds to TP53 gene]25446071|2544607
C022838nickel chloride[nickel chloride results in decreased activity of TP63 protein] inhibits the reaction [TP63 protein binds to TP53 gene]25446071
C022838nickel chloride[nickel chloride results in decreased activity of TP73 protein] inhibits the reaction [TP73 protein binds to TP53 gene]25446071
C022838nickel chloridenickel chloride results in increased expression of TP53 protein23566959|2855277
C022838nickel chloridenickel chloride results in increased expression of TP53 protein modified form28552779
C022838nickel chloridenickel chloride results in increased phosphorylation of and results in increased activity of TP53 protein23566959
C022838nickel chloridenickel chloride results in increased phosphorylation of TP53 protein21466819
C022838nickel chlorideTP53 mutant form inhibits the reaction [nickel chloride results in increased activity of CASP9 protein]23566959
C022838nickel chloride[TP53 mutant form inhibits the reaction [nickel chloride results in increased activity of CASP9 protein]] which results in decreased cleavage of CASP3 protein23566959
C022838nickel chlorideTP53 mutant form results in decreased susceptibility to nickel chloride23566959
C022838nickel chloride[TP53 mutant form results in decreased susceptibility to nickel chloride] which results in decreased cleavage of PARP1 protein23566959
C022838nickel chlorideTP53 protein affects the reaction [nickel chloride results in increased expression of BBC3 mRNA]23566959
C022838nickel chlorideTP53 protein affects the reaction [nickel chloride results in increased expression of BTG2 mRNA]23566959
C022838nickel chlorideTP53 protein affects the reaction [nickel chloride results in increased expression of CDKN1A mRNA]23566959
C022838nickel chlorideTP53 protein affects the reaction [nickel chloride results in increased expression of MCL1 mRNA]23566959
C022838nickel chlorideTP53 protein affects the reaction [nickel chloride results in increased expression of MDM2 mRNA]23566959
C022838nickel chloridenickel chloride affects the expression of TP53 mRNA22546817
C550717nickel ferritenickel ferrite analog results in increased expression of TP53 mRNA25966046
C550717nickel ferritenickel ferrite results in increased expression of TP53 mRNA21382431
C028007nickel monoxidenickel monoxide results in decreased expression of TP53 mRNA19167457
C017557nickel subsulfidenickel subsulfide results in decreased expression of TP53 mRNA24952340
C029938nickel sulfatenickel sulfate inhibits the reaction [Potassium Dichromate results in increased phosphorylation of TP53 protein]20493934
C029938nickel sulfatenickel sulfate results in increased expression of TP53 protein21776270|2356877
D009534Niclosamide[Niclosamide binds to Polyethyleneimine] which results in increased expression of TP53 mRNA25988281
D009534NiclosamideNiclosamide results in increased expression of TP53 mRNA22576131
D009538Nicotine4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [Nicotine results in decreased expression of TP53 protein]18805435
D009538NicotineNicotine inhibits the reaction [aflatoxin G1 results in increased expression of TP53 protein modified form]23907605
D009538NicotineNicotine inhibits the reaction [Cisplatin results in increased expression of TP53 protein]16601104
D009538NicotineNicotine inhibits the reaction [gemcitabine results in increased expression of TP53 protein]16601104
D009538NicotineNicotine inhibits the reaction [Paclitaxel results in increased expression of TP53 protein]16601104
D009538NicotineNicotine results in decreased expression of TP53 mRNA18247414
D009538NicotineNicotine results in decreased expression of TP53 protein16011614|1880543
D009538NicotineNicotine results in increased expression of TP53 protein20727180
D009538Nicotinerosiglitazone inhibits the reaction [Nicotine results in decreased expression of TP53 protein]19139119
D009538NicotineTP53 protein affects the reaction [Nicotine results in increased phosphorylation of MAPK1 protein]20727180
D009538NicotineTP53 protein affects the reaction [Nicotine results in increased phosphorylation of MAPK3 protein]20727180
D009538NicotineTP53 protein affects the reaction [Nicotine results in increased phosphorylation of MAPK8 protein]20727180
D009538NicotineNicotine affects the expression of TP53 mRNA10837795
D009538NicotineNicotine results in increased expression of TP53 mRNA20339300|2042688
D009538NicotineTP53 protein affects the susceptibility to Nicotine15983034
D009543NifedipineNifedipine results in increased activity of TP53 protein12082016
C042198nimbolidenimbolide results in increased expression of TP53 mRNA20429769
C042198nimbolidenimbolide results in increased expression of TP53 protein20429769
D015376NimustineTP53 affects the reaction [Nimustine results in increased expression of DDB2 mRNA]18089819
D015376NimustineTP53 affects the reaction [Nimustine results in increased expression of XPC mRNA]18089819
D015376NimustineTP53 protein affects the susceptibility to Nimustine15182437
D009569Nitric OxideNitric Oxide inhibits the reaction [Cadmium results in increased expression of TP53 mRNA]25490952
D009569Nitric Oxide2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nitric Oxide results in increased phosphorylation of TP53 protein]16024610
D009569Nitric OxideCaffeine inhibits the reaction [Nitric Oxide results in increased phosphorylation of TP53 protein]16024610
D009569Nitric Oxide[Nitric Oxide Donors results in increased abundance of Nitric Oxide] which results in increased expression of TP53 protein10608825
D009569Nitric OxideNitric Oxide results in increased expression of TP53 protein15979383
D009569Nitric OxideNitric Oxide results in increased glutathionylation of TP53 protein17555331
D009569Nitric OxideNitric Oxide results in increased phosphorylation of TP53 protein15177039|1602461
D009569Nitric OxideTP53 protein affects the susceptibility to Nitric Oxide16024610
D009569Nitric Oxidewortmannin inhibits the reaction [Nitric Oxide results in increased phosphorylation of TP53 protein]16024610
D009569Nitric Oxide[Nitroprusside results in increased abundance of Nitric Oxide] which results in increased expression of TP53 protein22293420
D009569Nitric Oxidepyrazolanthrone inhibits the reaction [[Nitroprusside results in increased abundance of Nitric Oxide] which results in increased expression of TP53 protein]22293420
D009569Nitric Oxide[7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat results in increased phosphorylation of TP53 protein]20478973
D009569Nitric Oxide[NOS2 protein results in increased abundance of Nitric Oxide] which results in increased expression of TP53 protein9743513
D009569Nitric Oxide[S-Nitrosoglutathione results in increased abundance of Nitric Oxide] which results in increased expression of TP53 protein8982730
D009569Nitric OxideATM protein affects the reaction [Nitric Oxide results in increased phosphorylation of TP53 protein]15177039
D020030Nitric Oxide Donors[Nitric Oxide Donors results in increased abundance of Nitric Oxide] which results in increased expression of TP53 protein10608825
D009583NitrofurazoneNitrofurazone results in increased mutagenesis of TP53 gene15488632
D009585Nitrogen DioxideNitrogen Dioxide results in increased expression of TP53 mRNA22621880
D009585Nitrogen DioxideNitrogen Dioxide results in increased expression of TP53 protein22621880
D009588Nitrogen Mustard Compoundscaffeic acid phenethyl ester inhibits the reaction [Nitrogen Mustard Compounds results in increased phosphorylation of TP53 protein]17204746
D009588Nitrogen Mustard CompoundsNitrogen Mustard Compounds results in increased phosphorylation of TP53 protein17204746
D009589Nitrogen OxidesNitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]16041517
D009599NitroprussideNitroprusside results in increased expression of TP53 protein15979383
D009599NitroprussideAcetylcysteine inhibits the reaction [Nitroprusside results in increased expression of TP53]19725096
D009599Nitroprusside[Nitroprusside results in increased abundance of Nitric Oxide] which results in increased expression of TP53 protein22293420
D009599NitroprussideNitroprusside results in increased expression of TP5319725096
D009599Nitroprussidepyrazolanthrone inhibits the reaction [[Nitroprusside results in increased abundance of Nitric Oxide] which results in increased expression of TP53 protein]22293420
D009599Nitroprussidecilostazol inhibits the reaction [Nitroprusside results in increased phosphorylation of TP53 protein]18311796
D009599NitroprussideNitroprusside results in increased phosphorylation of TP53 protein18311796
D0151124-Nitroquinoline-1-oxide4-Nitroquinoline-1-oxide results in decreased expression of TP53 protein20599846
D026423S-Nitroso-N-AcetylpenicillamineS-Nitroso-N-Acetylpenicillamine promotes the reaction [FGF2 protein results in increased expression of TP53 protein]16351512
D026422S-NitrosoglutathioneS-Nitrosoglutathione inhibits the reaction [PRKN protein binds to TP53 promoter]23985028
D026422S-NitrosoglutathioneS-Nitrosoglutathione inhibits the reaction [PRKN protein results in decreased expression of TP53 mRNA]23985028
D026422S-NitrosoglutathioneS-Nitrosoglutathione inhibits the reaction [PRKN protein results in decreased expression of TP53 protein]23985028
D026422S-Nitrosoglutathione[S-Nitrosoglutathione results in increased nitrosation of PRKN protein] inhibits the reaction [PRKN protein binds to TP53 promoter]23985028
D026422S-Nitrosoglutathione[S-Nitrosoglutathione results in increased nitrosation of PRKN protein] inhibits the reaction [PRKN protein results in decreased expression of TP53 mRNA]23985028
D026422S-Nitrosoglutathione[S-Nitrosoglutathione results in increased nitrosation of PRKN protein] inhibits the reaction [PRKN protein results in decreased expression of TP53 protein]23985028
D026422S-Nitrosoglutathione[S-Nitrosoglutathione results in increased abundance of Nitric Oxide] which results in increased expression of TP53 protein8982730
C419410N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester"Hydrogen Peroxide inhibits the reaction [N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in decreased expression of TP53 protein]"25005833
C419410N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester"N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in decreased expression of TP53 protein"25005833
C002741N-nitrosomorpholineN-nitrosomorpholine results in increased expression of TP53 protein10326863|1458703
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"[Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]"18951928
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the localization of TP53 protein"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]"18951928
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP53 protein"12888634
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of LATS2 mRNA]"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STAT3 mRNA]"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of KRT8 mRNA]"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RB1 mRNA]"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RPRM mRNA]"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SFN mRNA]"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TIMP3 mRNA]"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP73 mRNA]"18778698
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of YWHAZ mRNA]"18778698
D015739NocodazoleNocodazole analog results in increased expression of TP53 protein28412508
D015739NocodazoleNocodazole results in increased expression of TP53 protein21559451
D015739NocodazoleTP53 protein affects the reaction [Nocodazole results in increased phosphorylation of JUN protein]12221076
D015739NocodazoleTP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK8 protein]12221076
D015739NocodazoleTP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK9 protein]12221076
C099178nolatrexedTP53 protein affects the susceptibility to nolatrexed17339891
C010615Nonidet P-40Nonidet P-40 results in decreased expression of TP53 mRNA26552463
C025256nonylphenolnonylphenol affects the expression of TP53 mRNA17950039
C025256nonylphenolnonylphenol results in increased expression of TP53 mRNA14595849
D009640NorethindroneNorethindrone results in increased expression of and results in increased activity of TP53 protein15905198
D009665NoscapineNoscapine promotes the reaction [Cisplatin results in increased expression of TP53 protein]20674069
D009665NoscapineNoscapine results in increased expression of and results in increased phosphorylation of TP53 protein22848370
D009665NoscapineNoscapine results in increased expression of TP53 protein20674069
C118989NSC 652287NSC 652287 results in increased expression of TP53 protein mutant form21109480
C118989NSC 652287NSC 652287 results in increased phosphorylation of TP53 protein mutant form21109480
C118989NSC 652287TP53 protein affects the reaction [NSC 652287 results in increased expression of MDM2 mRNA]21109480
C118989NSC 652287TP53 protein promotes the reaction [NSC 652287 results in increased expression of MDM2 protein]21109480
C553898NSC 724998TP53 protein results in decreased susceptibility to NSC 72499825269479
C482205nutlin 3nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
C482205nutlin 3nutlin 3 inhibits the reaction [Camptothecin results in increased expression of TP53 protein]24726431
C482205nutlin 3nutlin 3 inhibits the reaction [TP53 protein binds to MDM2 protein]21509038|2226086
C482205nutlin 3[nutlin 3 inhibits the reaction [TP53 protein binds to MDM2 protein]] which results in increased activity of TP53 protein21509038
C482205nutlin 3nutlin 3 promotes the reaction [Cisplatin results in increased expression of TP53 mRNA]21109480
C482205nutlin 3nutlin 3 promotes the reaction [Cisplatin results in increased expression of TP53 protein]21624110
C482205nutlin 3nutlin 3 promotes the reaction [Cisplatin results in increased localization of TP53 protein]21109480
C482205nutlin 3nutlin 3 promotes the reaction [Doxorubicin results in increased expression of TP53 protein]21624110
C482205nutlin 3nutlin 3 promotes the reaction [Methotrexate results in increased expression of TP53 protein]21624110
C482205nutlin 3nutlin 3 promotes the reaction [TP53 protein binds to BCL2L1 protein]16014563
C482205nutlin 3nutlin 3 promotes the reaction [TP53 protein results in increased expression of FAS protein]21509038
C482205nutlin 3nutlin 3 results in increased activity of TP53 protein16014563
C482205nutlin 3nutlin 3 results in increased expression of and affects the localization of TP53 protein16014563
C482205nutlin 3nutlin 3 results in increased expression of and results in increased localization of and results in increased activity of TP53 protein21109480
C482205nutlin 3nutlin 3 results in increased expression of and results in increased phosphorylation of TP53 protein16439677
C482205nutlin 3nutlin 3 results in increased expression of TP53 mRNA22260869
C482205nutlin 3nutlin 3 results in increased expression of TP53 protein16439685|1809234
C482205nutlin 3nutlin 3 results in increased expression of TP53 protein modified form22044530
C482205nutlin 3nutlin 3 results in increased stability of TP53 protein21205074
C482205nutlin 3[nutlin 3 results in increased stability of TP53 protein] which results in increased susceptibility to Cisplatin21205074
C482205nutlin 3[nutlin 3 results in increased stability of TP53 protein] which results in increased susceptibility to Fluorouracil21205074
C482205nutlin 3nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]22044530
C482205nutlin 3nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein modified form]22044530
C482205nutlin 3Tetrachlorodibenzodioxin results in decreased susceptibility to [nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]22044530
C482205nutlin 3Tetrachlorodibenzodioxin results in decreased susceptibility to [nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein modified form]]22044530
C482205nutlin 3TP53 affects the reaction [nutlin 3 promotes the reaction [Cisplatin results in increased activity of and results in increased expression of CDKN1A protein]]21624110
C482205nutlin 3TP53 affects the reaction [nutlin 3 promotes the reaction [Cisplatin results in increased activity of and results in increased expression of MDM2 protein]]21624110
C482205nutlin 3TP53 affects the reaction [nutlin 3 promotes the reaction [Doxorubicin results in increased activity of and results in increased expression of CDKN1A protein]]21624110
C482205nutlin 3TP53 affects the reaction [nutlin 3 promotes the reaction [Doxorubicin results in increased activity of and results in increased expression of MDM2 protein]]21624110
C482205nutlin 3TP53 affects the reaction [nutlin 3 promotes the reaction [Methotrexate results in increased activity of and results in increased expression of CDKN1A protein]]21624110
C482205nutlin 3TP53 affects the reaction [nutlin 3 promotes the reaction [Methotrexate results in increased activity of and results in increased expression of MDM2 protein]]21624110
C482205nutlin 3TP53 affects the reaction [nutlin 3 results in increased activity of and results in increased expression of CDKN1A protein]21624110
C482205nutlin 3TP53 affects the reaction [nutlin 3 results in increased activity of and results in increased expression of MDM2 protein]21624110
C482205nutlin 3TP53 mutant form inhibits the reaction [nutlin 3 results in increased activity of CASP3 protein]22260869
C482205nutlin 3TP53 mutant form inhibits the reaction [nutlin 3 results in increased activity of CASP7 protein]22260869
C482205nutlin 3TP53 mutant form inhibits the reaction [nutlin 3 results in increased cleavage of PARP1 protein]22260869
C482205nutlin 3TP53 protein affects the reaction [nutlin 3 results in increased expression of BBC3 protein]16439685
C482205nutlin 3TP53 protein affects the reaction [nutlin 3 results in increased expression of CDKN1A protein]16439685
C482205nutlin 3TP53 protein affects the reaction [nutlin 3 results in increased expression of MDM2 protein]16439685
C482205nutlin 3TP53 protein promotes the reaction [nutlin 3 results in increased expression of BAX mRNA]21109480
C482205nutlin 3TP53 protein promotes the reaction [nutlin 3 results in increased expression of CDKN1A mRNA]21109480
C482205nutlin 3TP53 protein promotes the reaction [nutlin 3 results in increased expression of CDKN1A protein]21109480
C482205nutlin 3TP53 protein promotes the reaction [nutlin 3 results in increased expression of MDM2 mRNA]21109480
C482205nutlin 3TP53 protein promotes the reaction [nutlin 3 results in increased expression of MDM2 protein]21109480
C482205nutlin 3TP53 results in increased susceptibility to nutlin 321624110
C482205nutlin 3nutlin 3 inhibits the reaction [MDM2 protein binds to TP53 protein]16014563
C482205nutlin 3nutlin 3 inhibits the reaction [TP53 protein binds to MDM2 protein]22260869
C482205nutlin 3nutlin 3 results in decreased activity of [MDM2 protein binds to TP53 protein]21314128
C482205nutlin 3nutlin 3 results in increased activity of TP53 protein19098008
C064976O(6)-benzylguanine[Carmustine co-treated with O(6)-benzylguanine] results in increased expression of TP53 protein15735757
C064976O(6)-benzylguanine[temozolomide co-treated with O(6)-benzylguanine] results in increased expression of TP53 protein20980775
C064976O(6)-benzylguanineTP53 protein results in increased susceptibility to [temozolomide co-treated with O(6)-benzylguanine]20980775
C067207obacunoneobacunone results in increased expression of TP53 protein21333732|2559288
C411188obacunone glucosideobacunone glucoside results in increased expression of TP53 protein25592883
C066515O-(chloroacetylcarbamoyl)fumagillolO-(chloroacetylcarbamoyl)fumagillol results in increased expression of TP53 protein15276080
C025589ochratoxin Aochratoxin A results in increased expression of TP53 protein19367635|2828620
C025589ochratoxin ATP53 mutant form inhibits the reaction [ochratoxin A results in decreased expression of RAD51]24525463
C025589ochratoxin Aochratoxin A results in decreased expression of TP5325218026
C025589ochratoxin Aochratoxin A results in increased expression of TP53 mRNA19562491|2320842
C025589ochratoxin ANFE2L2 protein affects the reaction [ochratoxin A results in increased expression of TP53 protein]28710020
C025589ochratoxin Aochratoxin A results in increased expression of TP53 protein28710020
D015282OctreotideOctreotide results in decreased expression of TP53 protein21764706
D016627OxidopamineOxidopamine results in increased expression of TP53 protein17368433
D016627OxidopamineSN50 peptide inhibits the reaction [Oxidopamine results in increased expression of TP53 protein]17368433
D019319Okadaic AcidOkadaic Acid affects the localization of TP53 protein21512803
D019319Okadaic AcidOkadaic Acid affects the reaction [Estradiol promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]24954032
D019319Okadaic AcidOkadaic Acid affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]24954032
D019319Okadaic Acid"Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]"24954032
D019319Okadaic AcidOkadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]24954032
D019319Okadaic Acid"Okadaic Acid promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]"24954032
D019319Okadaic AcidOkadaic Acid results in decreased expression of TP53 protein18937299
C076029olanzapineolanzapine results in increased expression of TP53 mRNA16160616
C531550olaparib[Fluorouracil co-treated with olaparib] results in increased expression of TP53 protein26544897
C531550olaparibTP53 gene mutant form affects the reaction [benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AFX protein]]26544897
C013168olaquindoxolaquindox results in decreased expression of TP53 protein28757460
C013168olaquindoxolaquindox results in increased expression of TP53 mRNA21549799
C013168olaquindoxolaquindox results in increased expression of TP53 protein21549799
C013168olaquindoxpifithrin inhibits the reaction [olaquindox results in decreased expression of TP53 protein]28757460
C002769oleuropeinoleuropein inhibits the reaction [decamethrin results in increased expression of TP53 protein]28595958
C090046olomoucineolomoucine inhibits the reaction [TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]]16628227
C090046olomoucineolomoucine inhibits the reaction [TP53 results in decreased phosphorylation of CDK1 protein]16628227
C475587olomoucine IIolomoucine II results in increased expression of TP53 protein16003486
D015525Fatty Acids, Omega-3"TP53 protein affects the susceptibility to Fatty Acids, Omega-3"16043214
C507134ON 01910ON 01910 results in increased expression of and results in increased phosphorylation of TP53 protein25472472
C507134ON 01910TP53 protein affects the susceptibility to ON 0191023873848
C016340o,p'-DDT"o,p'-DDT analog results in increased expression of TP53 mRNA"22937105
C016340o,p'-DDT"o,p'-DDT analog results in increased expression of TP53 protein"22937105
C016340o,p'-DDT"o,p'-DDT results in increased expression of TP53 mRNA"22937105
C016340o,p'-DDT"o,p'-DDT results in increased expression of TP53 protein"22937105
D009942Organometallic CompoundsOrganometallic Compounds results in increased expression of and results in increased phosphorylation of TP53 protein26391003
D009942Organometallic CompoundsOrganometallic Compounds results in increased expression of TP53 protein17210701
D008939Mitotane[Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of TP53 protein9815696
D008939MitotaneMitotane analog affects the expression of TP53 protein23485034
D008939MitotaneMitotane analog results in increased expression of TP53 mRNA23485034
D008939MitotaneMitotane results in increased expression of TP53 mRNA23485034
D008939MitotaneMitotane results in increased expression of TP53 protein23485034
C030110oxaliplatinAcetylcysteine inhibits the reaction [oxaliplatin results in increased expression of TP53 protein]19728331
C030110oxaliplatinCaffeine inhibits the reaction [oxaliplatin results in increased expression of TP53 protein modified form]19735649
C030110oxaliplatinoxaliplatin affects the localization of TP53 protein modified form19735649
C030110oxaliplatinoxaliplatin promotes the reaction [TP53 protein binds to DUT promoter]19015155
C030110oxaliplatinoxaliplatin results in increased expression of TP53 protein19015155|1972833
C030110oxaliplatinoxaliplatin results in increased expression of TP53 protein modified form19735649|2070860
C030110oxaliplatinoxaliplatin results in increased phosphorylation of and results in increased activity of TP53 protein19728331
C030110oxaliplatin[pifithrin results in decreased activity of TP53 protein] results in decreased susceptibility to [oxaliplatin results in increased activity of CASP3 protein]20708607
C030110oxaliplatin[pifithrin results in decreased activity of TP53 protein] which results in decreased susceptibility to oxaliplatin20708607
C030110oxaliplatin[pifithrin results in decreased phosphorylation of TP53 protein] inhibits the reaction [oxaliplatin results in increased expression of H2AFX protein modified form]19735649
C030110oxaliplatinpifithrin results in decreased susceptibility to [oxaliplatin results in increased expression of TP53 protein]20708607
C030110oxaliplatinpifithrin results in decreased susceptibility to [oxaliplatin results in increased expression of TP53 protein modified form]20708607
C030110oxaliplatinTP53 mutant form inhibits the reaction [[oxaliplatin co-treated with Ursodeoxycholic Acid] results in increased activity of CASP3 protein]19728331
C030110oxaliplatinTP53 mutant form inhibits the reaction [[oxaliplatin co-treated with Ursodeoxycholic Acid] results in increased activity of CASP8 protein]19728331
C030110oxaliplatinTP53 protein affects the reaction [oxaliplatin results in decreased activity of DUT protein]19015155
C030110oxaliplatinTP53 protein affects the reaction [oxaliplatin results in decreased expression of DUT mRNA]19015155
C030110oxaliplatinTP53 protein affects the reaction [oxaliplatin results in decreased expression of DUT protein]19015155
C030110oxaliplatinTP53 protein affects the susceptibility to oxaliplatin15041737
C030110oxaliplatinTP53 protein promotes the reaction [oxaliplatin results in increased expression of CDKN1A protein]16227409
C030110oxaliplatinTP53 protein results in increased susceptibility to oxaliplatin16227409
C011030oxfendazoleoxfendazole results in decreased expression of TP53 mRNA26558467
D010100OxygenOxygen deficiency results in increased expression of TP53 protein10951577
D010100Oxygen"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]"10951577
D010100OxygenAcetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]10951577
D010100OxygenDitiocarb inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]10951577
D010100OxygenOxygen deficiency affects the activity of TP53 protein25596134
D010100OxygenOxygen deficiency inhibits the reaction [Etoposide results in increased phosphorylation of TP53 protein]23144690
D010100OxygenOxygen deficiency results in increased expression of and results in increased activity of TP53 protein10951577
D010100Oxygen[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of TP53 mRNA19578757
D010100Oxygen[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of TP53 protein19578757
D010100Oxygenmangiferin inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]10657591
D010100Oxygen[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of TP53 protein23451161
D010100OxygenOxygen deficiency results in increased expression of TP53 protein10657591
D010100OxygenTP53 protein affects the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NDRG2]23451161
D010100OxygenTP53 protein affects the susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]23451161
D017239Paclitaxel[Doxorubicin co-treated with Paclitaxel] results in increased expression of TP53 protein16168113
D017239PaclitaxelFluorouracil promotes the reaction [[Doxorubicin co-treated with Paclitaxel] results in increased expression of TP53 protein]16168113
D017239PaclitaxelNicotine inhibits the reaction [Paclitaxel results in increased expression of TP53 protein]16601104
D017239PaclitaxelPaclitaxel inhibits the reaction [TP53 gene mutant form results in decreased susceptibility to Platinum Compounds]12440809
D017239PaclitaxelPaclitaxel results in decreased expression of TP53 protein11774260
D017239PaclitaxelPaclitaxel results in increased expression of TP53 protein11774260|1208201
D017239PaclitaxelPaclitaxel results in increased expression of TP53 protein modified form18451153
D017239Paclitaxel[Paclitaxel results in increased expression of TP53 protein] which results in increased expression of BAX mRNA9041188
D017239Paclitaxel[Paclitaxel results in increased expression of TP53 protein] which results in increased expression of CDKN1A mRNA9041188
D017239Paclitaxel[Paclitaxel results in increased expression of TP53 protein] which results in increased expression of GADD45A mRNA9041188
D017239Paclitaxel[PD168393 co-treated with Paclitaxel] results in increased expression of TP53 protein16413505
D017239PaclitaxelTP53 protein results in decreased susceptibility to Paclitaxel15990222|1673473
D017239PaclitaxelPaclitaxel results in increased expression of TP53 protein9231689
C500026palbociclibTP53 protein mutant form results in decreased susceptibility to palbociclib21278246
D010168PalmitatesPalmitates results in increased acetylation of TP53 protein20068143
D010168Palmitatesresveratrol inhibits the reaction [Palmitates results in increased acetylation of TP53 protein]20068143
D010168PalmitatesSIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Palmitates results in increased acetylation of TP53 protein]]20068143
D019308Palmitic Acid[Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein24451382
D019308Palmitic AcidSIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased acetylation of TP53 protein]24451382
C496932panobinostat[panobinostat co-treated with SRT2183] results in increased acetylation of TP53 protein23681230
C496932panobinostatpanobinostat results in increased acetylation of TP53 protein23681230
D010269ParaquatParaquat results in increased expression of TP53 mRNA27288846
D010269ParaquatParaquat results in increased expression of TP53 mRNA15458575
D010269ParaquatParaquat promotes the reaction [Trientine results in increased phosphorylation of TP53 protein]11369509
D010269ParaquatParaquat results in increased expression of TP53 mRNA18836921|1952629
D010269ParaquatParaquat results in increased expression of TP53 protein10969820|1516284
D010269ParaquatParaquat results in increased phosphorylation of TP53 protein11369509
D010269ParaquatParaquat results in increased expression of TP5328428137
D010269Paraquat[7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat results in increased phosphorylation of TP53 protein]20478973
D010269ParaquatNFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of TP53 mRNA]22678742
D010269ParaquatParaquat results in decreased expression of TP53 mRNA18198484
D010269ParaquatParaquat results in increased expression of TP53 mRNA22678742|2491263
D010269ParaquatParaquat results in increased expression of TP53 protein17561093
D010269ParaquatParaquat results in increased phosphorylation of TP53 protein20478973
D010269ParaquatSodium Salicylate inhibits the reaction [Paraquat results in increased expression of TP53 protein]17561093
D010278ParathionAtropine inhibits the reaction [Parathion results in increased expression of TP53 protein]12762645
D010278Parathion[Parathion co-treated with Estradiol] results in increased expression of TP53 protein mutant form17622325
D010278ParathionParathion results in increased expression of TP53 protein12762645|1978726
D010278ParathionParathion results in increased expression of TP53 protein mutant form17390078|1762232
C002669parthenolideparthenolide results in increased expression of TP53 protein16024633
D052638Particulate MatterParticulate Matter analog results in increased mutagenesis of TP53 gene10682588
D052638Particulate Matter2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in decreased expression of TP53 protein]26942697
D052638Particulate MatterAcetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of TP53 protein]26942697
D052638Particulate MatterDNMT3B protein affects the reaction [Particulate Matter results in decreased expression of TP53 protein]26942697
D052638Particulate MatterDNMT3B protein affects the reaction [Particulate Matter results in increased methylation of TP53 promoter]26942697
D052638Particulate MatterParticulate Matter results in decreased expression of TP53 mRNA26942697|2836673
D052638Particulate MatterParticulate Matter results in decreased expression of TP53 protein26942697
D052638Particulate MatterParticulate Matter results in decreased phosphorylation of and results in decreased expression of TP53 protein25336953
D052638Particulate MatterParticulate Matter results in increased expression of TP53 mRNA23454527
D052638Particulate MatterParticulate Matter results in increased expression of TP53 protein20850422|2181862
D052638Particulate MatterParticulate Matter results in increased methylation of TP53 promoter26942697
D052638Particulate MatterParticulate Matter results in increased phosphorylation of TP53 protein20850422
D052638Particulate MatterTP53 protein polymorphism affects the susceptibility to Particulate Matter19750108
D052638Particulate Matter[[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of MDM2 protein] which results in increased expression of TP53 protein28013216
D052638Particulate Matter[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TP53 protein28013216
D052638Particulate MatterParticulate Matter results in increased expression of TP53 mRNA24216475
D010365PatulinPatulin results in increased expression of TP53 protein19744505
C410127PCB 180PCB 180 promotes the reaction [leptomycin B results in increased expression of TP53 protein]19751709
C410127PCB 180PCB 180 results in increased expression of TP53 protein19751709
C509204PD168393[PD168393 co-treated with Paclitaxel] results in increased expression of TP53 protein16413505
D000068437PemetrexedTP53 protein affects the reaction [Pemetrexed results in increased expression of FAS protein]15161716
D000068437PemetrexedTP53 protein affects the susceptibility to Pemetrexed17339891
D010396PenicillaminePenicillamine results in decreased expression of TP53 mRNA22843330
D010396PenicillaminePenicillamine results in increased expression of TP53 protein22843330
C074968pentaacetyl geniposidepentaacetyl geniposide results in increased activity of TP53 protein15975050
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of TP53 mRNA19858236
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of TP53 mRNA23948077
D010416PentachlorophenolPentachlorophenol results in increased mutagenesis of TP53 gene16904934
D010416PentachlorophenolPentachlorophenol affects the expression of TP53 protein12724925
D010416PentachlorophenolPentachlorophenol results in increased phosphorylation of TP53 protein19442831
D010419PentamidinePentamidine inhibits the reaction [KAT5 protein results in increased acetylation of TP53 protein]20144237
C046012pentanalpentanal results in decreased expression of TP53 mRNA26079696
D004369Pentetic AcidPentetic Acid inhibits the reaction [pyrithione zinc results in increased expression of TP53 protein]21557991
D004369Pentetic AcidPentetic Acid inhibits the reaction [pyrithione zinc results in increased phosphorylation of TP53 protein]21557991
C015423peoniflorinpeoniflorin inhibits the reaction [cobaltous chloride results in increased expression of TP53 mRNA]22269387
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of TP53 mRNA18407306
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of TP53 mRNA19468714
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of TP53 mRNA24616003
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of TP53 protein24616003
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of TP53 mRNA23427857
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of TP53 mRNA25868421
C011272perfosfamideAcetylcysteine inhibits the reaction [perfosfamide results in increased expression of TP53]18034189
C011272perfosfamideperfosfamide results in increased expression of TP5318034189
D010479PergolidePergolide inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]15081873
D010479PergolidePergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of BAX protein]15081873
D010479PergolidePergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein]15081873
D010479PergolidePergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein]15081873
D026023Permethrin[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TP53 protein12587291
C062400PFL protocolTP53 protein results in increased susceptibility to PFL protocol15611505
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in increased expression of TP53 protein16054126
D010630PhenindionePhenindione results in increased degradation of TP53 protein14634213
D010634Phenobarbitalmyrtenal inhibits the reaction [[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA]22436021
D010634Phenobarbitalmyrtenal inhibits the reaction [[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 protein]22436021
D010634Phenobarbital[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA22436021
D010634Phenobarbital[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TP53 protein22436021
D010634PhenobarbitalPhenobarbital promotes the reaction [Diethylnitrosamine results in increased expression of TP53 protein]11751435
D010634PhenobarbitalPhenobarbital results in decreased expression of TP53 mRNA25247799
D010634PhenobarbitalPhenobarbital results in decreased expression of TP53 protein25247799
D010634PhenobarbitalPhenobarbital results in increased expression of TP53 mRNA23273579
C066330phenylhydroquinonebathocuproine inhibits the reaction [[phenylhydroquinone co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
C066330phenylhydroquinoneCAT protein inhibits the reaction [[phenylhydroquinone co-treated with Copper] results in increased mutagenesis of TP53 gene]10334203
C066330phenylhydroquinone[phenylhydroquinone co-treated with Copper] results in increased mutagenesis of TP53 gene10334203
D010672PhenytoinPhenytoin results in increased expression of TP53 mRNA11134551
D010702PhoratePhorate results in increased expression of TP53 mRNA22197610
D010702PhoratePhorate results in increased expression of TP53 protein22197610
C003117phosaloneEllagic Acid inhibits the reaction [phosalone results in increased expression of TP53 mRNA]27965107
C003117phosaloneEllagic Acid inhibits the reaction [phosalone results in increased expression of TP53 protein]27965107
C003117phosalonephosalone results in increased expression of TP53 mRNA27965107
C003117phosalonephosalone results in increased expression of TP53 protein27965107
D010713PhosphatidylcholinesPhosphatidylcholines inhibits the reaction [rubitecan results in increased expression of TP53 protein]21695227
D054735Phosphorothioate OligonucleotidesPhosphorothioate Oligonucleotides results in increased expression of TP53 protein16498393
D010798PhycocyaninPhycocyanin inhibits the reaction [Galactose results in increased expression of TP53 protein]23036742
D010833Phytic Acid"Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]"16357363
D010833Phytic Acid"Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 protein]"16357363
D010833Phytic Acid"Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 protein]"16357363
D064209PhytochemicalsAcetylcysteine inhibits the reaction [Phytochemicals results in increased phosphorylation of TP53 protein]25305377
D064209PhytochemicalsPhytochemicals results in increased phosphorylation of TP53 protein25305377
C522973PI103PI103 inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]20856197
C522973PI103TP53 protein promotes the reaction [[Doxorubicin co-treated with PI103] results in increased expression of BBC3 protein]20856197
C522973PI103TP53 protein promotes the reaction [PI103 promotes the reaction [Doxorubicin results in increased activity of BAX protein]]20856197
C522973PI103TP53 protein promotes the reaction [PI103 promotes the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]20856197
C522973PI103TP53 protein promotes the reaction [PI103 promotes the reaction [Doxorubicin results in increased cleavage of CASP8 protein]]20856197
C522973PI103TP53 protein promotes the reaction [PI103 promotes the reaction [Doxorubicin results in increased cleavage of CASP9 protein]]20856197
C522973PI103TP53 protein results in increased susceptibility to [Doxorubicin co-treated with PI103]20856197
C121565pifithrin[pifithrin co-treated with cobaltous chloride] results in increased expression of and affects the localization of TP53 protein23380477
C121565pifithrin"pifithrin inhibits the reaction [Asbestos, Amosite affects the localization of TP53 protein]"16357363
C121565pifithrin"pifithrin inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 protein]"16357363
C121565pifithrinpifithrin inhibits the reaction [Azacitidine results in increased expression of TP53 protein]15547111
C121565pifithrinpifithrin inhibits the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]16258175
C121565pifithrinpifithrin inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]22226932
C121565pifithrinpifithrin inhibits the reaction [Celecoxib results in increased expression of TP53 protein]19706164
C121565pifithrinpifithrin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]21660965
C121565pifithrinpifithrin inhibits the reaction [CITED2 mutant form promotes the reaction [Cisplatin results in increased expression of TP53 protein]]21660965
C121565pifithrinpifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]]15735102
C121565pifithrinpifithrin inhibits the reaction [Etoposide results in increased activity of TP53 protein]16882877
C121565pifithrinpifithrin inhibits the reaction [goniothalamin results in increased phosphorylation of and results in increased expression of TP53 protein]21810437
C121565pifithrinpifithrin inhibits the reaction [[KITLG protein co-treated with EDN1 protein] results in increased phosphorylation of TP53 protein]19098008
C121565pifithrinpifithrin inhibits the reaction [KITLG protein results in increased phosphorylation of TP53 protein]19098008
C121565pifithrinpifithrin inhibits the reaction [olaquindox results in decreased expression of TP53 protein]28757460
C121565pifithrinpifithrin inhibits the reaction [Quercetin results in increased phosphorylation of TP53 protein]15735102|2298379
C121565pifithrinpifithrin inhibits the reaction [Reactive Oxygen Species affects the localization of TP53 protein]26884717
C121565pifithrinpifithrin inhibits the reaction [resveratrol results in increased expression of and results in increased phosphorylation of TP53 protein]11889192
C121565pifithrinpifithrin inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]16814113
C121565pifithrinpifithrin inhibits the reaction [silybin results in increased phosphorylation of TP53 protein]16777994
C121565pifithrinpifithrin inhibits the reaction [Simvastatin results in increased expression of TP53 protein]20045437
C121565pifithrinpifithrin inhibits the reaction [Smoke analog results in increased expression of TP53 mRNA]23665932
C121565pifithrinpifithrin inhibits the reaction [SOX30 protein results in increased expression of TP53 mRNA]25435374
C121565pifithrinpifithrin inhibits the reaction [SOX30 protein results in increased expression of TP53 protein]25435374
C121565pifithrinpifithrin inhibits the reaction [TP53 protein promotes the reaction [chromium hexavalent ion results in decreased expression of BUB1B protein]]22886373
C121565pifithrinpifithrin inhibits the reaction [TP53 protein results in increased susceptibility to resveratrol]23152798
C121565pifithrinpifithrin inhibits the reaction [TP53 protein results in increased susceptibility to trichostatin A]16467109
C121565pifithrinpifithrin inhibits the reaction [TP53 results in increased susceptibility to Celecoxib]19706164
C121565pifithrinpifithrin results in decreased activity of TP53 protein15547111|2087807
C121565pifithrin[pifithrin results in decreased activity of TP53 protein] results in decreased susceptibility to [oxaliplatin results in increased activity of CASP3 protein]20708607
C121565pifithrin[pifithrin results in decreased activity of TP53 protein] which results in decreased susceptibility to oxaliplatin20708607
C121565pifithrinpifithrin results in decreased expression of TP53 protein12893085|1646710
C121565pifithrinpifithrin results in decreased phosphorylation of TP53 protein19735649|2181043
C121565pifithrin[pifithrin results in decreased phosphorylation of TP53 protein] inhibits the reaction [oxaliplatin results in increased expression of H2AFX protein modified form]19735649
C121565pifithrinpifithrin results in decreased susceptibility to [oxaliplatin results in increased expression of TP53 protein]20708607
C121565pifithrinpifithrin results in decreased susceptibility to [oxaliplatin results in increased expression of TP53 protein modified form]20708607
C121565pifithrin[pifithrin results in decreased activity of TP53 protein] which results in decreased susceptibility to deoxynivalenol22491426
C121565pifithrinpifithrin inhibits the reaction [APP protein alternative form results in increased phosphorylation of TP53 protein]24567336
C121565pifithrinpifithrin inhibits the reaction [arsenic trioxide results in increased activity of TP53 protein]17487067
C121565pifithrinpifithrin inhibits the reaction [Camptothecin promotes the reaction [TP53 protein binds to CREBBP protein]]13679428
C121565pifithrinpifithrin inhibits the reaction [Camptothecin results in increased activity of TP53 protein]11279278|1367942
C121565pifithrinpifithrin inhibits the reaction [Cisplatin results in increased activity of TP53 protein]15315938
C121565pifithrin"pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein]"16005925
C121565pifithrinpifithrin inhibits the reaction [Doxorubicin results in increased expression of and results in increased localization of TP53 protein modified form]18775851
C121565pifithrinpifithrin inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein]16687611
C121565pifithrinpifithrin inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased localization of TP53 protein]18775851
C121565pifithrinpifithrin inhibits the reaction [Lipopolysaccharides results in increased localization of TP53 protein]12665479
C121565pifithrinpifithrin inhibits the reaction [TP53 protein results in increased expression of CDKN1A protein]15144874
C121565pifithrinpifithrin inhibits the reaction [TP53 protein results in increased susceptibility to Cisplatin]15315938
C121565pifithrinpifithrin results in decreased activity of TP53 protein11279278|1214304
C121565pifithrinpifithrin results in decreased expression of TP53 protein18364113
C121565pifithrinTP53 protein affects the reaction [pifithrin results in decreased expression of TGFA protein]12143041
C121565pifithrinpifithrin results in decreased activity of TP5319728331
C121565pifithrinpifithrin results in decreased activity of TP53 protein12967348|1575397
C121565pifithrinpifithrin results in decreased expression of TP53 mRNA21810437
C121565pifithrinpifithrin results in decreased susceptibility to [1-nitropyrene results in increased activity of TP53 protein]22044530
C121565pifithrinpifithrin results in decreased susceptibility to [Benzo(a)pyrene results in increased activity of TP53 protein]22044530
C049032pinosylvinpinosylvin results in increased expression of TP53 protein23333577
C032727piperidine"piperidine promotes the reaction [[Copper co-treated with 1,2-diphenylhydrazine] results in increased mutagenesis of TP53 gene]"10798712
C498077piperlongumininepiperlonguminine affects the localization of TP53 protein26026911
C006253pirinixic acidpirinixic acid results in increased expression of TP53 mRNA22484513
D010894PiroxicamPiroxicam promotes the reaction [Cisplatin results in increased expression of TP53 protein]21858171
D010936Plant ExtractsPlant Extracts inhibits the reaction [TNFSF10 protein results in increased expression of TP53 protein]20971099
D010936Plant ExtractsPlant Extracts results in decreased expression of TP53 mRNA22143989
D010936Plant ExtractsPlant Extracts results in increased expression of TP5321300767
D010936Plant ExtractsPlant Extracts results in increased expression of TP53 mRNA22143989|2391180
D010936Plant ExtractsPlant Extracts results in increased expression of TP53 protein18834353|2214398
D010936Plant ExtractsPlant Extracts inhibits the reaction [Cisplatin results in increased expression of TP53 mRNA]25640527
D010936Plant ExtractsPlant Extracts inhibits the reaction [decamethrin results in increased expression of TP53 protein]28595958
D010936Plant ExtractsPlant Extracts inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 protein]18367157
D010936Plant ExtractsPlant Extracts results in decreased expression of TP5325616030
D010936Plant ExtractsPlant Extracts results in increased expression of TP53 mRNA20521779
D010938Plant OilsPlant Oils results in increased expression of TP53 protein15961301
D028321Plant PreparationsLRP1 protein promotes the reaction [Plant Preparations results in increased phosphorylation of TP53 protein]27262837
D028321Plant PreparationsPlant Preparations results in increased phosphorylation of TP53 protein27262837
D028321Plant PreparationsPlant Preparations results in increased expression of TP53 mRNA24973489
D017671Platinum CompoundsPaclitaxel inhibits the reaction [TP53 gene mutant form results in decreased susceptibility to Platinum Compounds]12440809
D017671Platinum CompoundsTP53 affects the susceptibility to Platinum Compounds12440809
D017671Platinum CompoundsTP53 gene mutant form results in decreased susceptibility to Platinum Compounds12440809
C422648pluronic block copolymer p85pluronic block copolymer p85 promotes the reaction [Doxorubicin results in increased expression of TP53 mRNA]15939500
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls results in decreased expression of TP53 protein24960055
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls results in increased expression of TP53 protein24960055
D000072317Polychlorinated Dibenzodioxins"[Polychlorinated Dibenzodioxins co-treated with Dibenzofurans, Polychlorinated] results in increased expression of TP53 mRNA"17850846
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in decreased methylation of TP53 promoter19892797
D011094Polyethyleneimine[Niclosamide binds to Polyethyleneimine] which results in increased expression of TP53 mRNA25988281
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in increased expression of TP53 protein24583197
D011070Poly I-CTP53 protein affects the reaction [Poly I-C affects the localization of RELA protein]18779317
D011070Poly I-CTP53 protein affects the reaction [Poly I-C results in increased expression of CXCL8 mRNA]18779317
D011070Poly I-CTP53 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]18779317
D011070Poly I-CTP53 protein affects the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]18779317
D011070Poly I-CTP53 protein affects the reaction [Poly I-C results in increased phosphorylation of NFKBIA protein]18779317
D011070Poly I-CTP53 results in increased susceptibility to [Poly I-C co-treated with Fluorouracil]20367642
D059808PolyphenolsBleomycin promotes the reaction [Polyphenols results in increased expression of TP53 mRNA]26800624
D059808PolyphenolsPolyphenols promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]26800624
D059808PolyphenolsPolyphenols results in increased expression of TP53 mRNA26800624
C472086polyphenon Epolyphenon E results in increased expression of TP53 protein23285096
C472086polyphenon ETP53 mutant form promotes the reaction [polyphenon E results in decreased expression of HDAC1 protein]23285096
C472086polyphenon ETP53 mutant form promotes the reaction [polyphenon E results in decreased expression of HDAC2 protein]23285096
C472086polyphenon ETP53 mutant form promotes the reaction [polyphenon E results in decreased expression of HDAC3 protein]23285096
D011134PolysaccharidesPolysaccharides results in increased expression of TP53 mRNA23911803
C019536potassium bromate4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]20067818
C019536potassium bromateAscorbic Acid inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]20067818
C019536potassium bromatepotassium bromate results in increased phosphorylation of TP53 protein20067818
C019536potassium bromate4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]20067818
C019536potassium bromateAscorbic Acid inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]20067818
C019536potassium bromatepotassium bromate results in increased phosphorylation of TP53 protein20067818|2501566
D011189Potassium Chloride"[Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression of TP53 mRNA"22228705
C027373potassium chromate(VI)"2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein modified form]"25977998
C027373potassium chromate(VI)2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein modified form]25977998
C027373potassium chromate(VI)Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein]25977998
C027373potassium chromate(VI)Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of TP53 protein modified form]25977998
C027373potassium chromate(VI)"potassium chromate(VI) promotes the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide binds to TP53 gene]"12727806
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of TP53 protein25977998
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of TP53 protein modified form25977998
C120482potassium diazoacetatepotassium diazoacetate results in increased mutagenesis of TP53 gene16926174
D011192Potassium Dichromatenickel sulfate inhibits the reaction [Potassium Dichromate results in increased phosphorylation of TP53 protein]20493934
D011192Potassium DichromatePotassium Dichromate results in increased phosphorylation of TP53 protein20493934
D011192Potassium DichromateAcetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of TP53 protein]18563748
D011192Potassium DichromateAscorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of and results in increased phosphorylation of TP53 protein]21262251
D011192Potassium DichromateAscorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of TP53 mRNA]21262251
D011192Potassium DichromateAscorbic Acid inhibits the reaction [Potassium Dichromate results in increased localization of TP53 protein modified form]21262251
D011192Potassium Dichromatecarvedilol inhibits the reaction [Potassium Dichromate results in increased expression of TP53 protein]25245570
D011192Potassium DichromatePotassium Dichromate results in increased expression of and results in increased phosphorylation of TP53 protein21262251
D011192Potassium DichromatePotassium Dichromate results in increased expression of TP53 mRNA18547707|2126225
D011192Potassium DichromatePotassium Dichromate results in increased expression of TP53 protein18563748|2524557
D011192Potassium DichromatePotassium Dichromate results in increased localization of TP53 protein modified form21262251
D011205Povidone[Silver co-treated with Povidone] affects the phosphorylation of TP53 protein27387714
D011205Povidone[Silver co-treated with Povidone] results in decreased expression of TP53 mRNA27387714
D011205Povidone[Silver co-treated with Povidone] results in decreased expression of TP53 protein27387714
D017035PravastatinPravastatin inhibits the reaction [Fluorouracil results in decreased degradation of TP53 protein]15625077
D017035PravastatinPravastatin inhibits the reaction [leptomycin B results in decreased degradation of TP53 protein]15625077
D017035PravastatinPravastatin inhibits the reaction [lopinavir-ritonavir drug combination results in increased expression of TP53 protein]20884875
D017035PravastatinPravastatin inhibits the reaction [Ritonavir results in increased expression of TP53 protein]20884875
D017035Pravastatin[Pravastatin results in increased phosphorylation of MDM2 protein] which results in increased degradation of TP53 protein15625077
D017035PravastatinPravastatin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]20650967
C017674procyanidinprocyanidin results in decreased phosphorylation of TP53 protein15827326
D011374ProgesteroneProgesterone results in decreased expression of TP53 mRNA23012394
D011374ProgesteroneProgesterone results in decreased expression of TP53 protein14529565
D011374ProgesteroneProgesterone results in increased expression of TP53 mRNA18850315
D011374ProgesteroneProgesterone results in increased expression of TP53 protein18850315
D011374ProgesteroneTP53 mutant form inhibits the reaction [Progesterone results in increased expression of CDKN1A mRNA]18850315
D011374ProgesteroneTP53 mutant form inhibits the reaction [Progesterone results in increased expression of CDKN1A protein]18850315
D011374ProgesteroneTP53 mutant form inhibits the reaction [Progesterone results in increased expression of CDKN1B mRNA]18850315
D011374ProgesteroneTP53 mutant form inhibits the reaction [Progesterone results in increased expression of CDKN1B protein]18850315
D011374ProgesteroneTP53 protein results in increased susceptibility to Progesterone14529565
D011374Progesterone[Estradiol co-treated with Methylnitrosourea co-treated with Progesterone] results in decreased expression of TP53 mRNA20732338
D011374Progesterone[Methylnitrosourea co-treated with Progesterone] results in decreased expression of TP53 mRNA20732338
D011374Progesterone[TP53 protein co-treated with LEP protein] results in increased secretion of Progesterone22151798
D011374ProgesteroneTP53 protein results in decreased secretion of Progesterone22151798
D011374ProgesteroneTP53 protein results in decreased abundance of Progesterone18703674
D011372ProgestinsTP53 protein inhibits the reaction [Progestins results in increased expression of VEGFA mRNA]15860260
C066229prolinedithiocarbamate"[Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]"18951928
C066229prolinedithiocarbamateAcetylcysteine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]18951928
C066229prolinedithiocarbamatebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]18951928
C066229prolinedithiocarbamate"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]"18951928
C066229prolinedithiocarbamateprolinedithiocarbamate results in increased phosphorylation of TP53 protein18951928
C066229prolinedithiocarbamate[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein18951928
C066229prolinedithiocarbamateZinc Sulfate inhibits the reaction [prolinedithiocarbamate results in increased phosphorylation of TP53 protein]18951928
D011398PromethazinePromethazine results in decreased expression of TP53 mRNA26011634
C045950propiconazolepropiconazole results in decreased expression of TP53 mRNA26619215
C045950propiconazoleTP53 protein mutant form results in increased susceptibility to propiconazole26619215
C005556propionaldehydepropionaldehyde results in decreased expression of TP53 mRNA26079696
D015742PropofolPropofol results in increased expression of TP53 protein28804952
D015742PropofolPropofol inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]22015447
C006068propylparaben[propylparaben co-treated with Butylated Hydroxyanisole] results in increased expression of TP53 protein25086368
C006068propylparabenpropylparaben results in increased expression of TP53 protein25086368
D011441PropylthiouracilPropylthiouracil results in increased expression of TP53 mRNA24780913
D011458Prostaglandins ETP53 protein results in increased secretion of Prostaglandins E18703674
D011460Prostaglandins FTP53 protein results in decreased secretion of Prostaglandins F18703674
C043680ptaquilosideptaquiloside results in decreased expression of TP53 mRNA22143989
C043680ptaquilosideptaquiloside results in increased expression of TP53 mRNA22143989
C043680ptaquilosideptaquiloside results in increased expression of TP53 protein22143989
C107773pterostilbenepterostilbene results in increased expression of TP53 mRNA20152895
D011692Puromycin Aminonucleoside"1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]"17035936
D011692Puromycin AminonucleosideMelatonin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TP53 protein]14993511
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased expression of TP53 protein14993511|1511339
C513428pyrachlostrobin[iprodione co-treated with pyrachlostrobin] results in decreased expression of TP53 mRNA29091792
C513428pyrachlostrobin[iprodione co-treated with pyrimethanil co-treated with pyrachlostrobin co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C513428pyrachlostrobin[iprodione co-treated with pyrimethanil co-treated with pyrachlostrobin] results in increased expression of TP53 mRNA29091792
C513428pyrachlostrobinpyrachlostrobin results in increased expression of TP53 mRNA29091792
C513428pyrachlostrobin[pyrimethanil co-treated with pyrachlostrobin co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C513428pyrachlostrobin[pyrimethanil co-treated with pyrachlostrobin] results in decreased expression of TP53 mRNA29091792
C432165pyrazolanthroneMYC affects the reaction [pyrazolanthrone results in increased expression of TP53 protein]15034932
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein]"26630137
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased expression of TP53 protein modified form]"26630137
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Capsaicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein]17292493
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein]25939952
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Pyrogallol results in increased expression of TP53 protein]20191265
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [sodium arsenite results in increased phosphorylation of TP53 protein]22706169
C432165pyrazolanthronepyrazolanthrone results in decreased expression of TP53 protein16450001
C432165pyrazolanthronepyrazolanthrone results in increased expression of TP53 protein15034932|1606166
C432165pyrazolanthronepyrazolanthrone results in increased expression of TP53 protein modified form26630137
C432165pyrazolanthronepyrazolanthrone results in increased phosphorylation of TP53 protein25305377
C432165pyrazolanthrone[sodium arsenite co-treated with pyrazolanthrone] promotes the reaction [HSPA9 protein binds to TP53 protein modified form]22706169
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [[Nitroprusside results in increased abundance of Nitric Oxide] which results in increased expression of TP53 protein]22293420
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Colistin results in increased expression of TP53 protein]28842171
C432165pyrazolanthronepyrazolanthrone results in increased phosphorylation of TP53 protein16046226
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of TP53 mRNA"21152443
D011729Pyridostigmine Bromide[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TP53 protein12587291
C108337pyrimethanil[iprodione co-treated with pyrimethanil co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C108337pyrimethanil[iprodione co-treated with pyrimethanil co-treated with pyrachlostrobin co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C108337pyrimethanil[iprodione co-treated with pyrimethanil co-treated with pyrachlostrobin] results in increased expression of TP53 mRNA29091792
C108337pyrimethanil[iprodione co-treated with pyrimethanil] results in decreased expression of TP53 mRNA29091792
C108337pyrimethanil[pyrimethanil co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C108337pyrimethanil[pyrimethanil co-treated with pyrachlostrobin co-treated with acetamiprid] results in increased expression of TP53 mRNA29091792
C108337pyrimethanil[pyrimethanil co-treated with pyrachlostrobin] results in decreased expression of TP53 mRNA29091792
C108337pyrimethanilpyrimethanil results in decreased expression of TP53 mRNA29091792
C009131pyrimidin-2-one beta-ribofuranosidepyrimidin-2-one beta-ribofuranoside results in increased expression of TP53 protein23320119
C010423pyrithione zincPentetic Acid inhibits the reaction [pyrithione zinc results in increased expression of TP53 protein]21557991
C010423pyrithione zincPentetic Acid inhibits the reaction [pyrithione zinc results in increased phosphorylation of TP53 protein]21557991
C010423pyrithione zincpyrithione zinc results in increased expression of and results in increased phosphorylation of TP53 protein20151177
C010423pyrithione zincpyrithione zinc results in increased expression of TP53 mRNA21424779
C010423pyrithione zincpyrithione zinc results in increased expression of TP53 protein21557991
C010423pyrithione zincpyrithione zinc results in increased phosphorylation of and results in increased activity of TP53 protein21557991
D011748Pyrogallolpyrazolanthrone inhibits the reaction [Pyrogallol results in increased expression of TP53 protein]20191265
D011748PyrogallolPyrogallol results in increased expression of TP53 protein20191265
D011748PyrogallolSB 203580 inhibits the reaction [Pyrogallol results in increased expression of TP53 protein]20191265
C020972pyrrolidine dithiocarbamic acidbathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein]11964141
C020972pyrrolidine dithiocarbamic acid[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein11964141
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid results in increased oxidation of and results in increased expression of TP53 protein11964141
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid results in decreased expression of TP53 protein16049548
C438462pyrrolo(2,1-c)(1,4)benzodiazepine"[naphthalene binds to pyrrolo(2,1-c)(1,4)benzodiazepine] which results in increased expression of TP53 protein"21732540
D019289Pyruvic Acid[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]25997894
D011791QuartzQuartz results in decreased expression of TP53 mRNA27917503
D011794Quercetin[Cisplatin co-treated with Quercetin] results in decreased expression of TP53 mRNA27514524
D011794QuercetinEllagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]15735102
D011794QuercetinMIR34A mRNA affects the reaction [Quercetin results in increased acetylation of TP53 protein]25896587
D011794Quercetinpifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]]15735102
D011794Quercetinpifithrin inhibits the reaction [Quercetin results in increased phosphorylation of TP53 protein]15735102|2298379
D011794Quercetin[Quercetin analog co-treated with Nickel] results in increased expression of TP53 protein20577783
D011794QuercetinQuercetin analog results in increased expression of TP53 mRNA25289772
D011794QuercetinQuercetin analog results in increased expression of TP53 protein25289772
D011794QuercetinQuercetin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]25108166
D011794QuercetinQuercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of TP53 protein]15795422
D011794QuercetinQuercetin inhibits the reaction [KRAS protein affects the activity of TP53 protein]19424582
D011794QuercetinQuercetin results in decreased degradation of and results in increased stability of TP53 mRNA18323654
D011794QuercetinQuercetin results in decreased expression of TP53 mRNA23727915
D011794QuercetinQuercetin results in decreased expression of TP53 protein16948901|2484943
D011794QuercetinQuercetin results in decreased expression of TP53 protein mutant form16720314
D011794QuercetinQuercetin results in decreased ubiquitination of and results in increased stability of TP53 protein18323654
D011794QuercetinQuercetin results in increased acetylation of TP53 protein25896587
D011794QuercetinQuercetin results in increased expression of and affects the localization of TP53 protein23918355
D011794QuercetinQuercetin results in increased expression of and results in increased phosphorylation of TP53 protein15177039|1573510
D011794QuercetinQuercetin results in increased expression of TP53 mRNA14715546|1929363
D011794QuercetinQuercetin results in increased expression of TP53 protein17973296|1962356
D011794QuercetinQuercetin results in increased expression of TP53 protein modified form26341291
D011794QuercetinQuercetin results in increased phosphorylation of and results in increased activity of TP53 protein25078064
D011794QuercetinQuercetin results in increased phosphorylation of TP53 protein22983795
D011794QuercetinTP53 protein affects the reaction [Quercetin results in increased expression of MIR34A mRNA]25896587
D011794Quercetin"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of TP53 protein]"21294050
D011794Quercetin"[1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000) co-treated with Quercetin] results in increased expression of TP53 protein"23529952
D011794QuercetinAcetylcysteine inhibits the reaction [Quercetin analog results in decreased phosphorylation of TP53 protein]23907460
D011794Quercetin"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Quercetin analog results in decreased phosphorylation of TP53 protein]"23907460
D011794QuercetinQuercetin affects the expression of TP53 protein22000973
D011794QuercetinQuercetin analog results in increased expression of and results in decreased phosphorylation of TP53 protein23907460
D011794QuercetinQuercetin inhibits the reaction [aluminum lactate results in increased expression of TP53 protein]26944603
D011794QuercetinQuercetin inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]24902966
D011794QuercetinQuercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of TP53 mRNA]24316378
D011794QuercetinQuercetin inhibits the reaction [estradiol 3-benzoate results in increased expression of TP53 protein]24316378
D011794QuercetinQuercetin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]16647178|2752527
D011794QuercetinQuercetin results in increased expression of TP53 mRNA18095365
C523166quercetin 3-O-beta-(2''-galloyl)-rhamnopyranosidequercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [TNFSF10 protein results in increased expression of TP53 protein]23711929
C523166quercetin 3-O-beta-(2''-galloyl)-rhamnopyranosidequercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [7-ketocholesterol results in increased expression of TP53 protein]25845326
D011796QuinacrineQuinacrine results in increased activity of TP53 protein12082016
D011796QuinacrineQuinacrine results in increased stability of and results in increased activity of TP53 protein16177561
D011802QuinidineQuinidine results in decreased expression of TP53 mRNA17522070
C037219quinolinequinoline analog results in increased activity of TP53 protein12082016
C037219quinolinequinoline analog results in increased expression of TP53 protein18645022
C037219quinolinequinoline analog results in increased expression of TP53 protein mutant form18645022
C037219quinoline[quinoline analog results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein18645022
C004532quinonequinone results in increased expression of TP53 protein20499891
C527524R18 peptideR18 peptide promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]24954032
C068874raltitrexedTP53 protein affects the reaction [raltitrexed results in increased expression of FAS protein]15161716
C068874raltitrexedTP53 protein affects the susceptibility to raltitrexed17339891
C068874raltitrexedTP53 protein inhibits the reaction [raltitrexed results in increased phosphorylation of STAT1 protein]16204068
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in increased expression of TP53 protein11517458
D017382Reactive Oxygen SpeciesAcetylcysteine inhibits the reaction [Reactive Oxygen Species affects the localization of TP53 protein]26884717
D017382Reactive Oxygen SpeciesAcetylcysteine inhibits the reaction [TP53 protein results in increased abundance of Reactive Oxygen Species]15059885
D017382Reactive Oxygen Species[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in decreased expression of BCL2L11 protein27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in decreased expression of BCL2 protein27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of BCL2A1 protein27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of BCL2L1 protein27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of BID protein27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of DDR1 mRNA27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of ICAM1 mRNA27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of MCL1 protein27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of MDM2 protein27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of NR4A2 mRNA27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of PTGS2 mRNA27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of SCO2 protein27634759
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of SOCS1 mRNA27634759
D017382Reactive Oxygen Species[chromium hexavalent ion results in increased abundance of Reactive Oxygen Species] which results in increased activity of TP53 protein22886373
D017382Reactive Oxygen SpeciesCyclosporine inhibits the reaction [Reactive Oxygen Species affects the localization of TP53 protein]26884717
D017382Reactive Oxygen Speciespifithrin inhibits the reaction [Reactive Oxygen Species affects the localization of TP53 protein]26884717
D017382Reactive Oxygen SpeciesReactive Oxygen Species affects the localization of TP53 protein26884717
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in increased expression of TP53 protein10951577|2763475
D017382Reactive Oxygen Speciessanglifehrin A inhibits the reaction [Reactive Oxygen Species affects the localization of TP53 protein]26884717
D017382Reactive Oxygen Species[Sulindac results in increased abundance of Reactive Oxygen Species] which results in increased activity of TP53 protein17136320
D017382Reactive Oxygen SpeciesTP53 protein promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased abundance of Reactive Oxygen Species]15880691
D017382Reactive Oxygen SpeciesTP53 protein promotes the reaction [Copper results in increased abundance of Reactive Oxygen Species]15880691
D017382Reactive Oxygen SpeciesTP53 protein promotes the reaction [Reactive Oxygen Species results in increased expression of GPX1 protein]21042727
D017382Reactive Oxygen SpeciesTP53 protein promotes the reaction [Reactive Oxygen Species results in increased expression of SCO2 mRNA]21042727
D017382Reactive Oxygen SpeciesTP53 protein promotes the reaction [Reactive Oxygen Species results in increased expression of SOD2 protein]21042727
D017382Reactive Oxygen SpeciesTP53 protein promotes the reaction [Reactive Oxygen Species results in increased expression of TIGAR mRNA]21042727
D017382Reactive Oxygen SpeciesTP53 protein promotes the reaction [Zinc results in increased abundance of Reactive Oxygen Species]15880691
D017382Reactive Oxygen SpeciesTP53 protein results in increased abundance of Reactive Oxygen Species15059885
D017382Reactive Oxygen SpeciesTP53 protein affects the chemical synthesis of Reactive Oxygen Species15059885
C059514resveratrolresveratrol inhibits the reaction [IL1B protein results in increased activity of TP53 protein]19011540
C059514resveratrol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol affects the localization of TP53 protein]18446786
C059514resveratrol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol promotes the reaction [PTGS2 protein binds to TP53 protein modified form]]16928824
C059514resveratrol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased expression of TP53 mRNA]11889192
C059514resveratrol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of TP53 protein]12131363|1844678
C059514resveratrol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]11889192|1681411
C059514resveratrol"2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one promotes the reaction [TP53 protein results in increased susceptibility to resveratrol]"23152798
C059514resveratrol2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]17534123
C059514resveratrol2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]]24933654
C059514resveratrol2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Hydrogen Peroxide promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]]24933654
C059514resveratrol2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]]24933654
C059514resveratrol2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of TP53 protein]]24933654
C059514resveratrolarginyl-glycyl-aspartic acid inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]16790523
C059514resveratrolBCL2 protein inhibits the reaction [resveratrol promotes the reaction [PML protein binds to TP53 protein]]19631782
C059514resveratrolBleomycin promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]24933654
C059514resveratrolCapsaicin promotes the reaction [resveratrol results in increased expression of TP53 protein]19846903
C059514resveratrol[Doxorubicin co-treated with resveratrol] results in increased expression of TP53 mRNA26969377
C059514resveratrol[Doxorubicin co-treated with resveratrol] results in increased expression of TP53 protein26969377
C059514resveratrolEGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]15542774
C059514resveratrolEGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]15542774
C059514resveratrolErlotinib Hydrochloride promotes the reaction [resveratrol results in increased expression of TP53 protein]25895606
C059514resveratrolHRAS protein promotes the reaction [resveratrol results in increased expression of and results in increased phosphorylation of TP53 protein]11889192
C059514resveratrolHRAS protein promotes the reaction [resveratrol results in increased expression of TP53 mRNA]11889192
C059514resveratrolHRAS protein promotes the reaction [TP53 protein results in increased susceptibility to resveratrol]11889192
C059514resveratrolHydrogen Peroxide promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]24933654
C059514resveratrol[ITGA5 protein binds to ITGB3 protein] promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]16790523
C059514resveratrolmidostaurin affects the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]15542774
C059514resveratrolmidostaurin inhibits the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]]15542774
C059514resveratrolMRK 003 inhibits the reaction [resveratrol results in increased expression of TP53]21743969
C059514resveratrolMTA1 protein inhibits the reaction [resveratrol results in increased acetylation of TP53 protein]19810103
C059514resveratrolN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased expression of TP53 mRNA]29242151
C059514resveratrolN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]16928824|2924215
C059514resveratrol[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [resveratrol results in increased activity of TP53 protein]18446786
C059514resveratrolPARP1 protein affects the reaction [resveratrol results in increased acetylation of and results in increased phosphorylation of TP53 protein]25533949
C059514resveratrolpifithrin inhibits the reaction [resveratrol results in increased expression of and results in increased phosphorylation of TP53 protein]11889192
C059514resveratrolpifithrin inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]16814113
C059514resveratrolpifithrin inhibits the reaction [TP53 protein results in increased susceptibility to resveratrol]23152798
C059514resveratrolPRKCA protein affects the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]]15542774
C059514resveratrolresveratrol affects the expression of TP53 protein11522280
C059514resveratrol[resveratrol affects the localization of PTGS2 protein] which results in increased activity of TP53 protein18446786
C059514resveratrolresveratrol affects the localization of TP53 protein18446786|2458704
C059514resveratrolresveratrol analog results in increased expression of TP53 protein25776512|2697035
C059514resveratrol[resveratrol co-treated with AICA ribonucleotide] inhibits the reaction [Glucose results in increased expression of TP53 protein]26188290
C059514resveratrol[resveratrol co-treated with clofarabine] affects the localization of TP53 protein modified form24239893
C059514resveratrol[resveratrol co-treated with clofarabine] results in increased expression of and results in increased activity of TP53 protein modified form24239893
C059514resveratrolresveratrol inhibits the reaction [cudraflavone B results in increased expression of TP53 protein]23881456
C059514resveratrolresveratrol inhibits the reaction [Glucose affects the localization of TP53 protein]24218232
C059514resveratrolresveratrol inhibits the reaction [Glucose results in increased acetylation of TP53 protein]20068143
C059514resveratrolresveratrol inhibits the reaction [Glucose results in increased expression of TP53 mRNA]27049278
C059514resveratrolresveratrol inhibits the reaction [Glucose results in increased expression of TP53 protein]26188290
C059514resveratrolresveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]27049278
C059514resveratrolresveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]23859249
C059514resveratrolresveratrol inhibits the reaction [IL1B protein results in increased expression of TP53 protein]17959154
C059514resveratrolresveratrol inhibits the reaction [Palmitates results in increased acetylation of TP53 protein]20068143
C059514resveratrolresveratrol inhibits the reaction [Rotenone promotes the reaction [TP53 protein modified form binds to SIRT1 protein]]25991017
C059514resveratrolresveratrol inhibits the reaction [Rotenone results in increased expression of TP53 mRNA]25991017
C059514resveratrolresveratrol inhibits the reaction [Rotenone results in increased expression of TP53 protein]25991017
C059514resveratrolresveratrol inhibits the reaction [Rotenone results in increased expression of TP53 protein modified form]25991017
C059514resveratrolresveratrol inhibits the reaction [TNF protein results in increased acetylation of TP53 protein]23257246
C059514resveratrolresveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]15542774
C059514resveratrolresveratrol metabolite results in increased expression of TP53 protein11895857
C059514resveratrolresveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]24933654
C059514resveratrolresveratrol promotes the reaction [Capsaicin results in increased expression of TP53 protein]19846903
C059514resveratrolresveratrol promotes the reaction [Ceramides results in increased phosphorylation of TP53 protein]23495037
C059514resveratrolresveratrol promotes the reaction [Erlotinib Hydrochloride results in increased expression of TP53 protein]25895606
C059514resveratrolresveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of TP53 protein]24933654
C059514resveratrolresveratrol promotes the reaction [[LMNA protein binds to and results in increased activity of SIRT1 protein] which results in decreased acetylation of TP53 protein]23217256
C059514resveratrolresveratrol promotes the reaction [PML protein binds to TP53 protein]19631782
C059514resveratrolresveratrol promotes the reaction [PTGS2 protein binds to TP53 protein modified form]16928824
C059514resveratrolresveratrol promotes the reaction [TP53 protein binds to BECN1 protein]23088850
C059514resveratrolresveratrol promotes the reaction [TP53 protein binds to CDKN1A promoter]18446786
C059514resveratrolresveratrol promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA]11895857
C059514resveratrolresveratrol promotes the reaction [TP53 protein binds to PML protein binds to CREBBP protein]19631782
C059514resveratrolresveratrol results in decreased activity of TP53 protein22252971|2595647
C059514resveratrol[[resveratrol results in decreased expression of MTA1 protein] inhibits the reaction [MTA1 protein binds to HDAC1 protein]] which results in increased acetylation of and results in increased activity of TP53 protein19810103
C059514resveratrolresveratrol results in increased acetylation of and results in increased activity of TP53 protein19810103
C059514resveratrol[resveratrol results in increased acetylation of and results in increased activity of TP53 protein] promotes the reaction [TP53 protein binds to BAX promoter]19810103
C059514resveratrol[resveratrol results in increased acetylation of and results in increased activity of TP53 protein] promotes the reaction [TP53 protein binds to CDKN1A promoter]19810103
C059514resveratrolresveratrol results in increased acetylation of and results in increased phosphorylation of TP53 protein25533949
C059514resveratrolresveratrol results in increased activity of and results in increased acetylation of TP53 protein24603648
C059514resveratrol[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [Hydrogen Peroxide results in increased acetylation of TP53 protein]18681908
C059514resveratrolresveratrol results in increased activity of TP53 protein17174366|2050436
C059514resveratrolresveratrol results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein12131363
C059514resveratrolresveratrol results in increased expression of and results in increased phosphorylation of TP53 protein11889192|1955972
C059514resveratrol[resveratrol results in increased expression of and results in increased phosphorylation of TP53 protein] which results in increased expression of CDKN1A mRNA11889192
C059514resveratrolresveratrol results in increased expression of TP5316209266|2174396
C059514resveratrolresveratrol results in increased expression of TP53 mRNA11889192|1514987
C059514resveratrol[resveratrol results in increased expression of TP53] promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15]11895857
C059514resveratrolresveratrol results in increased expression of TP53 protein11895857|1599384
C059514resveratrolresveratrol results in increased expression of TP53 protein modified form26341291
C059514resveratrol[resveratrol results in increased expression of TP53 protein] which results in increased expression of GDF15 protein11895857
C059514resveratrolresveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein15542774
C059514resveratrolresveratrol results in increased phosphorylation of and results in increased activity of TP53 protein17534123|1786864
C059514resveratrolresveratrol results in increased phosphorylation of TP53 protein16790523|1681411
C059514resveratrol[resveratrol results in increased phosphorylation of TP53 protein] which results in increased expression of BAX protein18222423
C059514resveratrol[resveratrol results in increased phosphorylation of TP53 protein] which results in increased expression of CDKN1A protein18222423
C059514resveratrolSIRT1 mutant form inhibits the reaction [resveratrol inhibits the reaction [TNF protein results in increased acetylation of TP53 protein]]23257246
C059514resveratrolSIRT1 protein inhibits the reaction [resveratrol results in increased acetylation of TP53 protein]24603648
C059514resveratrolSIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in increased acetylation of TP53 protein]]20068143
C059514resveratrolSIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Palmitates results in increased acetylation of TP53 protein]]20068143
C059514resveratrolStaurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]]15542774
C059514resveratrolStaurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]]15542774
C059514resveratrolStaurosporine promotes the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]15542774
C059514resveratrolSUMO1 protein affects the reaction [resveratrol results in increased expression of TP53 mRNA]29242151
C059514resveratrolTetradecanoylphorbol Acetate inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of TP53 protein]15542774
C059514resveratrolThyroxine inhibits the reaction [resveratrol results in increased activity of TP53 protein]17174366
C059514resveratrolTP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]]19846903
C059514resveratrolTP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]]19846903
C059514resveratrolTP53 affects the reaction [resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]]18497562
C059514resveratrolTP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]]19846903
C059514resveratrolTP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]]19846903
C059514resveratrolTP53 affects the reaction [resveratrol results in decreased expression of MDM2 protein]19846903
C059514resveratrolTP53 affects the reaction [resveratrol results in increased activity of CASP6 protein]18497562
C059514resveratrolTP53 affects the reaction [resveratrol results in increased expression of BAX protein]19846903
C059514resveratrolTP53 affects the reaction [resveratrol results in increased expression of NOS1 protein]19846903
C059514resveratrolTP53 affects the reaction [resveratrol results in increased expression of NOS3 protein]19846903
C059514resveratrolTP53 affects the susceptibility to resveratrol18497562|1984690
C059514resveratrolTP53 mutant form inhibits the reaction [resveratrol results in decreased expression of NANOG protein]23651583
C059514resveratrolTP53 protein affects the susceptibility to [resveratrol co-treated with clofarabine]24239893
C059514resveratrolTP53 protein promotes the reaction [resveratrol promotes the reaction [CASP6 protein results in increased cleavage of LMNA protein]]16518869
C059514resveratrolTP53 protein promotes the reaction [resveratrol results in increased expression of CDKN1A mRNA]12131363
C059514resveratrolTP53 protein results in increased susceptibility to resveratrol11889192|1651886
C059514resveratrolvorinostat promotes the reaction [resveratrol results in increased acetylation of TP53 protein]19810103
C059514resveratrolwortmannin inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]17534123
C059514resveratrolYARS protein affects the reaction [resveratrol results in increased acetylation of TP53 protein]25533949
C059514resveratrol"1-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-2,7,9a-benzo(cd)azulen-6-one inhibits the reaction [resveratrol results in increased acetylation of TP53 protein]"25533949
C059514resveratrolresveratrol results in increased acetylation of TP53 protein25533949
C059514resveratrolN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]17984113
C059514resveratrolresveratrol inhibits the reaction [Cadmium Chloride results in increased expression of TP53 mRNA]24492640
C059514resveratrolresveratrol inhibits the reaction [Estradiol results in decreased expression of TP53 protein]24894866
C059514resveratrolresveratrol inhibits the reaction [Methylnitronitrosoguanidine results in increased acetylation of TP53 protein]17147953
C059514resveratrolresveratrol inhibits the reaction [Streptozocin results in increased expression of TP53 protein]23792339
C059514resveratrolresveratrol results in decreased expression of TP53 protein23792339
C059514resveratrolresveratrol results in increased expression of TP53 protein20797428
C059514resveratrolresveratrol results in increased expression of TP53 protein modified form20972827
C059514resveratrolresveratrol results in increased phosphorylation of TP53 protein17984113
C059514resveratrolTP53 protein promotes the reaction [resveratrol results in increased expression of CDKN1A mRNA]20797428
C059514resveratrolresveratrol results in increased expression of and results in increased acetylation of TP53 protein23065251
C059514resveratrolG3BP1 protein affects the reaction [resveratrol results in increased expression of TP53]24998844
C059514resveratrolresveratrol results in decreased ubiquitination of TP53 protein24998844
C059514resveratrol[resveratrol results in decreased ubiquitination of TP53 protein] which results in increased expression of TP53 protein24998844
C059514resveratrolresveratrol results in increased expression of TP5324998844
D012176RetinoidsRetinoids analog results in increased phosphorylation of TP53 protein17512204
D012176RetinoidsRetinoids results in increased phosphorylation of and results in increased activity of TP53 protein19067706
C013672riddelliineriddelliine results in increased expression of TP53 protein12460743|2073700
D019438RitonavirFTI 277 inhibits the reaction [Ritonavir results in increased expression of TP53 protein]20884875
D019438Ritonavirmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Ritonavir results in increased expression of TP53 protein]20884875
D019438RitonavirPravastatin inhibits the reaction [Ritonavir results in increased expression of TP53 protein]20884875
D019438RitonavirRitonavir results in increased expression of TP53 protein19386116|2088487
C512984RO 3306MYC mutant form inhibits the reaction [RO 3306 results in increased expression of TP53 protein]24444383
C512984RO 3306[RO 3306 co-treated with MYC protein] results in increased expression of TP53 protein24444383
C512984RO 3306RO 3306 results in increased expression of TP53 protein24444383
C071721Ro 41-0960Ro 41-0960 results in increased expression of TP53 mRNA21896544
C104586roscovitineroscovitine results in increased expression of TP53 protein16003486|1614093
C089730rosiglitazonerosiglitazone affects the activity of TP53 protein25596134
C089730rosiglitazonerosiglitazone inhibits the reaction [Nicotine results in decreased expression of TP53 protein]19139119
C089730rosiglitazonerosiglitazone results in decreased expression of TP53 protein17018897
C089730rosiglitazonerosiglitazone results in increased expression of TP53 mRNA17639046
C089730rosiglitazonerosiglitazone results in increased expression of TP53 protein17639046|1913911
C089730rosiglitazone[rosiglitazone results in increased expression of TP53 protein] promotes the reaction [rosiglitazone results in decreased expression of CHRNA4 protein]19139119
C089730rosiglitazonerosiglitazone affects the activity of TP53 protein25596134
D012402RotenoneRotenone results in increased expression of TP53 mRNA22560901
D012402Rotenoneresveratrol inhibits the reaction [Rotenone promotes the reaction [TP53 protein modified form binds to SIRT1 protein]]25991017
D012402Rotenoneresveratrol inhibits the reaction [Rotenone results in increased expression of TP53 mRNA]25991017
D012402Rotenoneresveratrol inhibits the reaction [Rotenone results in increased expression of TP53 protein]25991017
D012402Rotenoneresveratrol inhibits the reaction [Rotenone results in increased expression of TP53 protein modified form]25991017
D012402RotenoneRotenone affects the localization of TP53 protein21223980
D012402RotenoneRotenone promotes the reaction [TP53 protein modified form binds to SIRT1 protein]25991017
D012402RotenoneRotenone results in increased expression of and results in increased phosphorylation of TP53 protein21223980
D012402RotenoneRotenone results in increased expression of TP53 mRNA18191903|2396399
D012402RotenoneRotenone results in increased expression of TP53 protein23963993|2599101
D012402RotenoneRotenone results in increased expression of TP53 protein modified form25991017
D012402RotenoneGAPDH mutant form inhibits the reaction [Rotenone results in increased expression of TP53 protein]25725130
D012402RotenoneRotenone results in increased expression of TP53 protein25725130
C079905rubitecanPhosphatidylcholines inhibits the reaction [rubitecan results in increased expression of TP53 protein]21695227
C079905rubitecanrubitecan results in increased expression of TP53 protein21695227
D012428RutheniumRuthenium results in increased expression of TP53 protein17210701
D017975Ruthenium CompoundsRuthenium Compounds results in increased expression of TP53 protein17210701
D012431Rutin"Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of TP53 mRNA]"27239252
C033110RV 538RV 538 affects the splicing of and results in increased expression of TP53 mRNA25195822
C033110RV 538RV 538 results in increased phosphorylation of TP53 protein25195822
C039961S-(1,2-dichlorovinyl)cysteine"S-(1,2-dichlorovinyl)cysteine results in increased expression of TP53 protein"15967204
C046570S-(2-chloroethyl)glutathioneS-(2-chloroethyl)glutathione results in increased mutagenesis of TP53 gene14715658
C046570S-(2-chloroethyl)glutathione[S-(2-chloroethyl)glutathione results in increased mutagenesis of TP53 gene] which results in decreased activity of TP53 protein14715658|1471565
C076944salvianolic acid Bsalvianolic acid B results in decreased acetylation of TP53 protein24769256
C076944salvianolic acid Bsalvianolic acid B inhibits the reaction [Ethanol results in increased acetylation of TP53 protein]24769256
C121329sanglifehrin Asanglifehrin A inhibits the reaction [Reactive Oxygen Species affects the localization of TP53 protein]26884717
C044363sappanchalconesappanchalcone results in increased expression of TP53 protein21963806
C003402sapropterinsapropterin inhibits the reaction [Methotrexate results in increased expression of TP53 protein]22183962
C028268satratoxin Gsatratoxin G results in increased expression of TP53 mRNA18535002
C093642SB 203580SB 203580 inhibits the reaction [[Cisplatin co-treated with fisetin] results in increased phosphorylation of TP53 protein]21216935
C093642SB 203580SB 203580 inhibits the reaction [Curcumin results in increased phosphorylation of TP53 protein]19020741
C093642SB 203580SB 203580 inhibits the reaction [Pyrogallol results in increased expression of TP53 protein]20191265
C093642SB 203580SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of TP53 protein]19082730
C093642SB 203580SB 203580 inhibits the reaction [sodium arsenite results in increased expression of TP53 protein]15734884
C093642SB 203580SB 203580 inhibits the reaction [Sulindac affects the localization of TP53 protein]17136320
C093642SB 203580SB 203580 inhibits the reaction [Ethanol results in increased expression of and results in increased phosphorylation of TP53 protein]27270636
C093642SB 203580"SB 203580 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein]"16005925
C417521SB 216763SB 216763 inhibits the reaction [sodium arsenite results in increased expression of and affects the localization of TP53 protein]17849503
C417521SB 216763SB 216763 results in increased expression of TP53 protein15958644|1721070
C499748SCIO-469SCIO-469 promotes the reaction [Bortezomib results in increased expression of TP53 protein]16617327
C066198SDZ 51641SDZ 51641 results in increased expression of TP53 mRNA19234235
C110822SDZ CPI 975SDZ CPI 975 results in increased expression of TP53 mRNA19234235
C094089SDZ FOX 988SDZ FOX 988 results in increased expression of TP53 mRNA19234235
D012643SeleniumSelenium inhibits the reaction [Cadmium Chloride results in increased expression of TP53 mRNA]25035189
D012643Selenium[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of TP53 mRNA]27920530
D012643Selenium[Selenium co-treated with Vitamin E] results in increased expression of TP53 mRNA19244175
D012643SeleniumSelenium results in decreased expression of TP53 protein17523932
D012643SeleniumSelenium results in increased expression of TP53 mRNA19244175
D012643SeleniumSelenium inhibits the reaction [Cadmium Chloride results in increased expression of TP53 protein]16600092
D012643Selenium[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 mRNA]21628957
D064588Selenium OxidesSelenium Oxides results in increased expression of TP5315485790
D064588Selenium OxidesSelenium Oxides results in increased expression of TP53 protein11342237
D012645SelenomethionineAR protein promotes the reaction [Selenomethionine results in increased expression of TP53 mRNA]17205524
D012645SelenomethionineSelenomethionine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of TP53 protein]21515331
D012645SelenomethionineSelenomethionine results in decreased activity of TP53 protein17100737
D012645SelenomethionineSelenomethionine results in increased expression of TP53 mRNA17205524
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of TP53 protein"12676607
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased phosphorylation of TP53 protein"12676607
D017632Asbestos, Serpentine"wortmannin inhibits the reaction [Asbestos, Serpentine results in increased expression of TP53 protein]"12676607
D017632Asbestos, Serpentine"wortmannin inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of TP53 protein]"12676607
C042431S-ethyl glutathioneS-ethyl glutathione inhibits the reaction [Camptothecin results in increased expression of TP53 protein modified form]17555331
C042431S-ethyl glutathioneS-ethyl glutathione inhibits the reaction [tert-Butylhydroperoxide results in increased expression of TP53 protein modified form]17555331
C009250sevofluranesevoflurane results in increased expression of TP53 mRNA19572936
C016101shikoninshikonin results in increased expression of TP53 protein28684144
D000068677Sildenafil CitrateTP53 protein inhibits the reaction [Sildenafil Citrate results in increased susceptibility to Doxorubicin]20155316
D012822Silicon DioxideAscorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of TP53 mRNA]22245848
D012822Silicon DioxideAscorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of TP53 protein]22245848
D012822Silicon Dioxidefisetin inhibits the reaction [Silicon Dioxide results in increased expression of TP53 mRNA]22931364
D012822Silicon DioxideSilicon Dioxide results in decreased expression of TP53 mRNA25351596
D012822Silicon DioxideSilicon Dioxide results in increased expression of TP53 mRNA22245848|2293136
D012822Silicon DioxideSilicon Dioxide results in increased expression of TP53 protein20060462|2224584
D012822Silicon DioxideSilicon Dioxide results in increased expression of TP53 protein26865670
D012822Silicon DioxideZC3H12A affects the reaction [Silicon Dioxide results in increased expression of TP53 protein]26865670
D012834SilverSilver analog results in decreased expression of TP53 mRNA23800688
D012834SilverNFE2L2 protein affects the reaction [Silver results in increased expression of TP53 protein]22546375
D012834Silver[Silver co-treated with Povidone] affects the phosphorylation of TP53 protein27387714
D012834Silver[Silver co-treated with Povidone] results in decreased expression of TP53 mRNA27387714
D012834Silver[Silver co-treated with Povidone] results in decreased expression of TP53 protein27387714
D012834SilverSilver results in increased expression of TP53 protein22546375
D012834SilverSilver analog results in increased expression of TP53 mRNA22727896
D012835Silver NitrateSilver Nitrate analog results in decreased expression of TP53 mRNA22831968
D012835Silver NitrateSilver Nitrate results in increased expression of TP53 mRNA22727896
C440975silybinCaffeine inhibits the reaction [silybin results in increased phosphorylation of TP53 protein]16777994
C440975silybinpifithrin inhibits the reaction [silybin results in increased phosphorylation of TP53 protein]16777994
C440975silybinsilybin affects the localization of TP53 protein16777994
C440975silybinsilybin inhibits the reaction [Mitomycin results in increased expression of TP53]19834285
C440975silybinsilybin results in increased expression of TP53 protein16777994
C440975silybinsilybin results in increased phosphorylation of TP53 protein16777994
D019821Simvastatinpifithrin inhibits the reaction [Simvastatin results in increased expression of TP53 protein]20045437
D019821SimvastatinSimvastatin promotes the reaction [Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]]15625077
D019821SimvastatinSimvastatin promotes the reaction [TP53 protein binds to CD44 promoter]21199873
D019821SimvastatinSimvastatin results in increased expression of and results in increased phosphorylation of TP53 protein21199873
D019821SimvastatinSimvastatin results in increased expression of TP53 mRNA21199873
D019821SimvastatinSimvastatin results in increased expression of TP53 mutant form21199873
D019821SimvastatinSimvastatin results in increased expression of TP53 protein20045437|2119987
D019821SimvastatinSimvastatin results in increased phosphorylation of TP53 protein20045437
D019821SimvastatinSimvastatin results in increased expression of TP53 protein18804536
D020123SirolimusSirolimus promotes the reaction [TP53 protein results in increased expression of BBC3 protein]19560264
D020123Sirolimus[Sirolimus results in decreased activity of MTOR protein] which results in decreased phosphorylation of TP53 protein11602639
D020123SirolimusSirolimus results in decreased phosphorylation of TP53 protein11602639
D020123SirolimusSirolimus results in increased expression of TP53 mRNA24971338
C439060sirtinolsirtinol promotes the reaction [arsenic disulfide results in increased expression of and results in increased phosphorylation of TP53 protein]18298901
C439060sirtinolsirtinol promotes the reaction [cudraflavone B results in increased expression of TP53 protein]23881456
C439060sirtinol[sirtinol results in decreased activity of SIRT1 protein] promotes the reaction [Hydrogen Peroxide results in increased acetylation of TP53 protein]18681908
C027744S-methylisothiopseudouroniumS-methylisothiopseudouronium inhibits the reaction [IL1B protein results in increased expression of TP53 protein]12384474
D012906Smokepifithrin inhibits the reaction [Smoke analog results in increased expression of TP53 mRNA]23665932
D012906SmokeSmoke analog results in increased expression of TP53 mRNA23665932
D012906SmokeSmoke analog results in increased phosphorylation of TP53 protein23665932
D012906SmokeSmoke results in increased activity of TP53 protein22516759
C118258SN50 peptideSN50 peptide inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]15081873
C118258SN50 peptideSN50 peptide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of BAX protein]15081873
C118258SN50 peptideSN50 peptide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein]15081873
C118258SN50 peptideSN50 peptide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein]15081873
C118258SN50 peptideSN50 peptide inhibits the reaction [Oxidopamine results in increased expression of TP53 protein]17368433
C021315S-nitrosocysteineS-nitrosocysteine inhibits the reaction [SIRT1 protein results in decreased acetylation of TP53 protein]24451382
C009277sodium arsenatesodium arsenate results in increased expression of TP53 mRNA24349563
C017947sodium arsenite3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [sodium arsenite results in decreased phosphorylation of TP53 protein]22706169
C017947sodium arsenite3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [sodium arsenite affects the localization of TP53 protein]20375080
C017947sodium arsenite3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [sodium arsenite results in increased phosphorylation of TP53 protein]20375080
C017947sodium arsenite4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone inhibits the reaction [sodium arsenite affects the localization of TP53 protein]19931552
C017947sodium arsenite4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone inhibits the reaction [sodium arsenite results in increased activity of TP53 protein]19931552
C017947sodium arseniteATM gene mutant form inhibits the reaction [sodium arsenite results in increased expression of TP53 protein]11507245
C017947sodium arsenitebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of TP53 protein mutant form]21454520
C017947sodium arsenitecaffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in decreased expression of TP53 protein]22692362
C017947sodium arseniteHIF1A protein affects the reaction [sodium arsenite results in decreased phosphorylation of TP53 protein]27287256
C017947sodium arseniteHSPA9 protein inhibits the reaction [sodium arsenite affects the localization of TP53 protein]20375080
C017947sodium arseniteHSPA9 protein inhibits the reaction [sodium arsenite results in increased phosphorylation of TP53 protein]20375080
C017947sodium arseniteleptomycin B inhibits the reaction [sodium arsenite affects the localization of TP53 protein]19010883
C017947sodium arseniteleptomycin B inhibits the reaction [sodium arsenite results in increased degradation of TP53 protein mutant form]21454520
C017947sodium arseniteLithium inhibits the reaction [sodium arsenite results in increased expression of and affects the localization of TP53 protein]17849503
C017947sodium arseniteMAP2K4 mutant form affects the reaction [sodium arsenite results in increased expression of TP53 protein]15734884
C017947sodium arseniteMAPK1 protein promotes the reaction [sodium arsenite results in decreased expression of TP53 protein]28785074
C017947sodium arsenitepyrazolanthrone inhibits the reaction [sodium arsenite results in increased phosphorylation of TP53 protein]22706169
C017947sodium arseniteSB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of TP53 protein]19082730
C017947sodium arseniteSB 203580 inhibits the reaction [sodium arsenite results in increased expression of TP53 protein]15734884
C017947sodium arseniteSB 216763 inhibits the reaction [sodium arsenite results in increased expression of and affects the localization of TP53 protein]17849503
C017947sodium arsenitesodium arsenite affects the expression of TP53 mRNA23804311
C017947sodium arsenitesodium arsenite affects the localization of TP53 protein19010883|1993155
C017947sodium arsenite[sodium arsenite co-treated with leptomycin B] results in increased phosphorylation of TP53 protein19010883
C017947sodium arsenite[sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of TP53 mRNA23192986
C017947sodium arsenite[sodium arsenite co-treated with pyrazolanthrone] promotes the reaction [HSPA9 protein binds to TP53 protein modified form]22706169
C017947sodium arsenite[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of TP53 protein19082730
C017947sodium arsenitesodium arsenite inhibits the reaction [Cisplatin results in increased expression of TP53 protein]21696631
C017947sodium arsenitesodium arsenite promotes the reaction [MAPK8 protein binds to MAPK9 protein binds to TP53 protein modified form]22706169
C017947sodium arsenitesodium arsenite promotes the reaction [TP53 protein binds to ATF3 promoter]26148435
C017947sodium arsenitesodium arsenite promotes the reaction [TP53 protein binds to SESN1 promoter]26148435
C017947sodium arsenitesodium arsenite results in decreased expression of and affects the localization of TP53 protein28785074
C017947sodium arsenitesodium arsenite results in decreased expression of and results in increased degradation of TP53 protein mutant form21454520
C017947sodium arsenitesodium arsenite results in decreased expression of TP53 mRNA12377979|1961534
C017947sodium arsenitesodium arsenite results in decreased expression of TP53 protein17567589|2269236
C017947sodium arsenitesodium arsenite results in decreased expression of TP53 protein modified form22706169
C017947sodium arsenitesodium arsenite results in decreased expression of TP53 protein mutant form21454520
C017947sodium arsenitesodium arsenite results in decreased methylation of TP53 gene25199682
C017947sodium arsenitesodium arsenite results in decreased phosphorylation of TP53 protein22706169|2728725
C017947sodium arsenitesodium arsenite results in increased activity of TP53 protein17567589|1993155
C017947sodium arsenitesodium arsenite results in increased expression of and affects the localization of TP53 protein17849503
C017947sodium arsenitesodium arsenite results in increased expression of and results in increased phosphorylation of and results in decreased acetylation of TP53 protein29319823
C017947sodium arsenitesodium arsenite results in increased expression of TP53 mRNA15734884|2609179
C017947sodium arsenitesodium arsenite results in increased expression of TP53 protein11507245|1181326
C017947sodium arsenitesodium arsenite results in increased expression of TP53 protein modified form16338954|2270616
C017947sodium arsenitesodium arsenite results in increased methylation of TP53 promoter22551203
C017947sodium arsenitesodium arsenite results in increased phosphorylation of TP53 protein16614167|2037508
C017947sodium arsenitesodium arsenite results in increased ribosylation of TP53 protein20036271
C017947sodium arseniteSodium Selenite inhibits the reaction [sodium arsenite results in increased expression of TP53 protein]20390378
C017947sodium arseniteTP53 mutant form inhibits the reaction [sodium arsenite results in decreased expression of BIRC5 protein]22706169
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in decreased expression of MIR200B mRNA]21292642
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in decreased expression of MIR200C mRNA]21292642
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in decreased expression of MIR205 mRNA]21292642
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in increased expression of and results in decreased degradation of CCNB1 protein]16614167
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in increased expression of FZD2 mRNA]16966095
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in increased expression of MIR605 mRNA]21292642
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in increased expression of UBE2C mRNA]16966095
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in increased expression of UBE2K mRNA]16966095
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in increased expression of UBE2N mRNA]16966095
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in increased susceptibility to Cisplatin]22331493
C017947sodium arseniteTP53 protein affects the susceptibility to sodium arsenite16338954|2000047
C017947sodium arseniteTP53 protein inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]16614167
C017947sodium arseniteTP53 protein inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]16614167
C017947sodium arseniteTP53 protein inhibits the reaction [sodium arsenite results in increased expression of and results in increased phosphorylation of CDK1 protein]16614167
C017947sodium arseniteTP53 protein mutant form affects the susceptibility to sodium arsenite17567589
C017947sodium arseniteTP53 protein mutant form inhibits the reaction [sodium arsenite results in increased expression of MDM2 mRNA]28785074
C017947sodium arseniteTP53 protein mutant form results in decreased susceptibility to sodium arsenite21454520
C017947sodium arseniteTP53 protein promotes the reaction [sodium arsenite results in increased expression of DLX2 mRNA]16966095
C017947sodium arseniteTP53 protein promotes the reaction [sodium arsenite results in increased expression of DUSP1 mRNA]16966095
C017947sodium arseniteTP53 protein promotes the reaction [sodium arsenite results in increased expression of HSPA1A mRNA]16966095
C017947sodium arseniteTP53 protein promotes the reaction [sodium arsenite results in increased expression of ID1 mRNA]16966095
C017947sodium arseniteTP53 protein promotes the reaction [sodium arsenite results in increased expression of ID1 protein]16966095
C017947sodium arseniteTP53 protein promotes the reaction [sodium arsenite results in increased expression of MDM2 protein]20375080
C017947sodium arseniteTP53 protein results in decreased susceptibility to sodium arsenite16614167
C017947sodium arsenitetyrphostin AG 1478 inhibits the reaction [sodium arsenite results in increased expression of TP53 protein]15734884
C017947sodium arsenitetyrphostin AG825 inhibits the reaction [sodium arsenite results in increased expression of TP53 protein]15734884
C017947sodium arseniteU 0126 inhibits the reaction [sodium arsenite results in decreased phosphorylation of TP53 protein]22706169
C017947sodium arsenitesodium arsenite results in increased expression of TP53 protein16338954
C017947sodium arsenitesodium arsenite results in decreased expression of TP53 protein28785074
C017947sodium arsenitesodium arsenite results in increased expression of TP53 protein16797887
C017947sodium arsenitesodium arsenite results in increased expression of TP5313129816
D020160Sodium Benzoate"Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]"16357363
C016104sodium bichromateAspirin inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]10942736
C016104sodium bichromateCAT protein inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]10942736
C016104sodium bichromateDeferoxamine inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]10942736
C016104sodium bichromateformic acid inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]10942736
C016104sodium bichromateNADP promotes the reaction [sodium bichromate results in increased expression of TP53 protein]10942736
C016104sodium bichromatesodium bichromate results in decreased expression of TP53 mRNA27825931
C016104sodium bichromatesodium bichromate results in increased expression of TP53 mRNA26091798
C016104sodium bichromatesodium bichromate results in increased expression of TP53 protein10942736
C016104sodium bichromatesodium bichromate results in increased phosphorylation of TP53 protein26091798
C016104sodium bichromatesodium bichromate affects the expression of TP53 mRNA11960910
C016104sodium bichromatesodium bichromate results in increased expression of TP53 mRNA22561333
D012965Sodium ChlorideSodium Chloride results in increased expression of TP53 mRNA23634900
D012965Sodium Chlorideacetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]22431579
D012965Sodium Chlorideatrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]22431579
D012965Sodium Chloride[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein22431579
D017673Sodium Chloride, Dietary"[Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression of TP53 mRNA"22228705
C028982sodium chromate(VI)sodium chromate(VI) results in increased expression of TP53 protein16283527
D0150862,6-Dichloroindophenol"[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased phosphorylation of TP53 protein"21034357
D012969Sodium FluorideSodium Fluoride results in increased expression of TP53 mRNA22525295
D012969Sodium FluorideSodium Fluoride results in increased expression of TP53 protein22525295
D012980Sodium SalicylateSodium Salicylate inhibits the reaction [Paraquat results in increased expression of TP53 protein]17561093
D018038Sodium SeleniteSodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of TP53 protein]21515331
D018038Sodium SeleniteSodium Selenite inhibits the reaction [sodium arsenite results in increased expression of TP53 protein]20390378
D018038Sodium SeleniteSodium Selenite results in increased phosphorylation of TP53 protein15845651
D018038Sodium SeleniteTP53 protein affects the susceptibility to Sodium Selenite22200533
D053260SootSoot results in decreased expression of TP53 mRNA23634900
D053260SootSoot results in decreased expression of TP53 mRNA21914721
C471405sorafenibsorafenib promotes the reaction [GSK3B protein results in increased phosphorylation of TP53 protein]17991738
C013195sparfosic acidsparfosic acid results in increased expression of and affects the localization of TP53 protein8548770
C091861spermine nitric oxide complexspermine nitric oxide complex inhibits the reaction [Cadmium results in increased expression of TP53 mRNA]25490952
C091861spermine nitric oxide complex2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spermine nitric oxide complex results in increased phosphorylation of TP53 protein]16024610
C091861spermine nitric oxide complexCaffeine inhibits the reaction [spermine nitric oxide complex results in increased phosphorylation of TP53 protein]16024610
C091861spermine nitric oxide complexspermine nitric oxide complex results in increased phosphorylation of TP53 protein16024610
C091861spermine nitric oxide complexTP53 protein affects the susceptibility to spermine nitric oxide complex16024610
C091861spermine nitric oxide complexwortmannin inhibits the reaction [spermine nitric oxide complex results in increased phosphorylation of TP53 protein]16024610
C525423SRT2183[panobinostat co-treated with SRT2183] results in increased acetylation of TP53 protein23681230
C530804S,S'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea"S,S'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea results in increased expression of TP53 protein"19497413
D019311StaurosporineStaurosporine results in increased expression of TP53 protein20886113
D019311StaurosporineStaurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]]15542774
D019311StaurosporineStaurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]]15542774
D019311StaurosporineStaurosporine promotes the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]15542774
D019311StaurosporineHR protein inhibits the reaction [Staurosporine results in increased expression of TP53 protein]20886113
D013267StilbenesStilbenes results in increased expression of TP53 protein23059970
D013267Stilbenes[Stilbenes results in increased expression of TP53 protein] which results in increased expression of BAX protein23059970
D013311Streptozocinresveratrol inhibits the reaction [Streptozocin results in increased expression of TP53 protein]23792339
D013311StreptozocinStreptozocin results in increased expression of TP53 protein15976052|2379233
C013690styrene oxidestyrene oxide affects the expression of TP53 mRNA11230554
D013458Sulfur Dioxide[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 mRNA19408242
D013458Sulfur Dioxide[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 protein19408242
D013458Sulfur DioxideSulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 mRNA]20064080
D013458Sulfur DioxideSulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]20064080
D013458Sulfur DioxideSulfur Dioxide results in increased expression of TP53 mRNA19408242|1943469
D013458Sulfur DioxideSulfur Dioxide results in increased expression of TP53 protein19408242|1943469
D013467SulindacSB 203580 inhibits the reaction [Sulindac affects the localization of TP53 protein]17136320
D013467SulindacSulindac affects the localization of TP53 protein17136320
D013467Sulindac[Sulindac results in increased abundance of Reactive Oxygen Species] which results in increased activity of TP53 protein17136320
D013467SulindacSulindac results in increased expression of TP53 protein15713900
C025462sulindac sulfidesulindac sulfide results in decreased expression of TP53 protein9192825
C473643sulphoraphenesulphoraphene results in increased expression of and affects the localization of TP53 protein29247643
D013498SuraminSuramin results in decreased activity of [SIRT1 protein results in decreased acetylation of TP53 protein]18482975
D013605T-2 ToxinBentonite inhibits the reaction [[HT-2 toxin co-treated with T-2 Toxin] results in increased expression of TP53 mRNA]25296281
D013605T-2 Toxin[HT-2 toxin co-treated with T-2 Toxin] results in increased expression of TP53 mRNA25296281
D013605T-2 ToxinT-2 Toxin results in increased expression of TP53 protein19524637
D013605T-2 ToxinT-2 Toxin results in increased expression of TP53 mRNA21296132
D013605T-2 ToxinT-2 Toxin results in increased expression of TP53 protein21296132
D013619TacrineTacrine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]12414117
D013619TacrineTacrine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]12414117
D016559TacrolimusTacrolimus inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]12642403
D013629TamoxifenTamoxifen results in increased expression of TP53 mRNA26908177
D013629TamoxifenTamoxifen results in increased expression of TP53 protein16450001|2054969
D013629TamoxifenTP53 gene mutant form results in decreased susceptibility to Tamoxifen10786679
D013629TamoxifenTP53 protein affects the susceptibility to Tamoxifen15832264
D013629TamoxifenTP53 protein inhibits the reaction [Tamoxifen results in decreased phosphorylation of AKT1 protein]20549698
D013629TamoxifenTP53 protein inhibits the reaction [Tamoxifen results in decreased phosphorylation of MAPK1 protein]20549698
D013629TamoxifenTP53 protein inhibits the reaction [Tamoxifen results in decreased phosphorylation of MAPK3 protein]20549698
D013629TamoxifenTP53 protein inhibits the reaction [Tamoxifen results in increased expression of ESR1 protein]20549698
D013629TamoxifenTP53 protein promotes the reaction [Tamoxifen results in decreased expression of BCL2 mRNA]20549698
D013629TamoxifenTP53 protein promotes the reaction [Tamoxifen results in increased expression of GADD45A mRNA]20549698
D013629TamoxifenTP53 protein results in increased susceptibility to Tamoxifen20549698
D013629TamoxifenTamoxifen results in increased mutagenesis of TP53 gene8033108
C112765tanespimycintanespimycin results in decreased expression of TP53 protein10564678
C021751tanshinonetanshinone results in decreased expression of TP53 protein19885617|2036947
C021751tanshinonetanshinone results in increased expression of TP53 protein16009009
C030141taurine-ursodeoxycholate conjugatetaurine-ursodeoxycholate conjugate inhibits the reaction [E2F1 protein results in increased expression of TP53 protein]14514686
C030141taurine-ursodeoxycholate conjugatetaurine-ursodeoxycholate conjugate inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein]14514686
C030141taurine-ursodeoxycholate conjugatetaurine-ursodeoxycholate conjugate inhibits the reaction [TP53 protein results in increased expression of BAX protein]14514686
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid inhibits the reaction [TP53 protein results in increased expression of BAX mRNA]17881359
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in increased expression of and results in increased stability of TP53 protein15255934
C031655tauroursodeoxycholic acidTP53 protein affects the susceptibility to tauroursodeoxycholic acid17431217
C508490TDP 521252TDP 521252 inhibits the reaction [MDM2 protein binds to TP53 protein]16432175
C508490TDP 521252TDP 521252 results in increased stability of TP53 protein16432175
C508491TDP 665759TDP 665759 inhibits the reaction [MDM2 protein binds to TP53 protein]16432175
C508491TDP 665759TDP 665759 results in increased stability of TP53 protein16432175
D013662TeaBleomycin promotes the reaction [Tea results in increased expression of TP53 mRNA]26800624
D013662TeaTea promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]26800624
D013662TeaTea results in increased expression of TP53 mRNA26800624
D013662TeaTea inhibits the reaction [decamethrin results in increased expression of TP53 mRNA]26013673
D013662TeaTea inhibits the reaction [decamethrin results in increased expression of TP53 protein]26013673
D005641TegafurTP53 protein affects the susceptibility to Tegafur15182437
D005641TegafurTP53 protein affects the susceptibility to [Uracil co-treated with Tegafur]15182437
C047246temozolomide[temozolomide co-treated with O(6)-benzylguanine] results in increased expression of TP53 protein20980775
C047246temozolomidetemozolomide results in increased expression of TP53 protein16193384
C047246temozolomideTP53 protein promotes the reaction [temozolomide results in increased expression of PMAIP1 mRNA]17216584
C047246temozolomideTP53 protein results in decreased susceptibility to temozolomide16193384
C047246temozolomideTP53 protein results in increased susceptibility to temozolomide16405512
C047246temozolomideTP53 protein results in increased susceptibility to [temozolomide co-treated with O(6)-benzylguanine]20980775
C001803tempoltempol results in increased expression of TP53 protein15601469
C505333TEMPOL-HTEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 mRNA]24369695
C505333TEMPOL-HTEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 protein]24369695
C037565terbutylazineterbutylazine results in decreased stability of and results in increased degradation of and results in increased mutagenesis of TP53 gene22445671
D016593TerfenadineTerfenadine results in increased expression of TP53 protein12244568
D013739Testosterone[Testosterone co-treated with gingerol] results in increased expression of TP53 protein18030663
D013739Testosteronechrysin inhibits the reaction [Testosterone results in decreased expression of TP53 mRNA]29247772
D013739TestosteroneTestosterone results in decreased expression of TP53 mRNA29247772
C534735tetraarsenic tetrasulfidearsenic trioxide promotes the reaction [tetraarsenic tetrasulfide results in increased expression of TP53 protein]26110921
C534735tetraarsenic tetrasulfide(+)-JQ1 compound promotes the reaction [tetraarsenic tetrasulfide results in increased expression of TP53 protein]26586936
C534735tetraarsenic tetrasulfidetetraarsenic tetrasulfide promotes the reaction [arsenic trioxide results in increased expression of TP53 protein]26110921
C534735tetraarsenic tetrasulfidetetraarsenic tetrasulfide promotes the reaction [(+)-JQ1 compound results in increased expression of TP53 protein]26586936
C534735tetraarsenic tetrasulfidetetraarsenic tetrasulfide results in increased expression of TP53 protein26110921|2658693
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased expression of TP53 mRNA24596333
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased expression of TP53 mRNA28970181
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased mutagenesis of TP53 gene26353976
C000591600tetrachlorobenzoquinonetetrachlorobenzoquinone affects the reaction [TP53 protein binds to RAD51 protein]27989139
C000591600tetrachlorobenzoquinonetetrachlorobenzoquinone results in increased expression of and results in increased phosphorylation of TP53 protein27989139
C000591600tetrachlorobenzoquinoneTP53 protein promotes the reaction [tetrachlorobenzoquinone results in decreased expression of RAD51 protein]27989139
C000591600tetrachlorobenzoquinoneTP53 protein promotes the reaction [tetrachlorobenzoquinone results in increased expression of CASP3 protein modified form]27989139
C000591600tetrachlorobenzoquinoneTP53 protein promotes the reaction [tetrachlorobenzoquinone results in increased expression of H2AFX protein modified form]27989139
C000591600tetrachlorobenzoquinoneTP53 protein results in increased susceptibility to tetrachlorobenzoquinone27989139
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of TP53 protein22015590
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the phosphorylation of TP53 protein22015590
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of TP53 mRNA24349563
D013749Tetrachlorodibenzodioxin2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased susceptibility to [Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]22044530
D013749Tetrachlorodibenzodioxin3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TP53 mRNA]17070097
D013749Tetrachlorodibenzodioxin3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TP53 protein]17070097
D013749TetrachlorodibenzodioxinCYP1A1 protein affects the susceptibility to [Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]22044530
D013749Tetrachlorodibenzodioxinfostriecin promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]24954032
D013749TetrachlorodibenzodioxinOkadaic Acid affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]]24954032
D013749TetrachlorodibenzodioxinOkadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene affects the localization of TP53 protein]]24954032
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of TP53 mRNA19578757
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of TP53 protein19578757
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased acetylation of TP53 protein]20299546
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of TP53 protein]20299546
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene affects the localization of and results in increased expression of TP53 protein]24954032
D013749Tetrachlorodibenzodioxin"Tetrachlorodibenzodioxin promotes the reaction [dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein]"24954032
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of TP53 mRNA17070097
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of TP53 protein17070097
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]22044530
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein modified form]22044530
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased susceptibility to [nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]]22044530
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased susceptibility to [nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of TP53 protein modified form]]22044530
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of TP53 protein9707505
D013749TetrachlorodibenzodioxinAHR protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of TP53 protein]]15459018
D013749TetrachlorodibenzodioxinAHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of TP53 protein]15093247
D013749Tetrachlorodibenzodioxinalpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [leptomycin B results in increased expression of TP53 protein]]15459018
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of TP53 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of and results in increased phosphorylation of TP53 protein]15459018
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Diethylnitrosamine results in increased expression of and results in increased phosphorylation of TP53 protein]15459018
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of TP53 protein]15459018
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Fluorouracil results in increased expression of TP53 protein]15459018
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [leptomycin B results in increased expression of TP53 protein]15459018
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of and results in increased phosphorylation of TP53 protein15093247
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of TP53 protein8640813
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased degradation of TP53 protein15459018
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TP53 mRNA19520675
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased activity of TP53 protein22044530
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased activity of TP53 protein]22044530
D013750TetrachloroethyleneTetrachloroethylene results in increased expression of TP53 protein12160929
D013752TetracyclineTetracycline results in increased expression of TP53 mRNA17522070
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of TP53 protein]15542774
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in decreased expression of TP53 protein10910098
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of TP53 protein8076368|8927716
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TP53 mRNA25613284
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of TP53 protein8076368
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased activity of TP5320454814
C011126tetraiodothyroacetic acidtetraiodothyroacetic acid inhibits the reaction [Thyroxine affects the localization of TP53 protein modified form]17984113
C050950tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complextetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex affects the expression of TP53 protein16002045
D007978LevamisoleLevamisole results in decreased expression of TP53 mRNA11139434
D007978LevamisoleLevamisole results in decreased expression of TP53 protein11139434
C020809tetrathiomolybdate[Copper deficiency co-treated with tetrathiomolybdate] results in increased expression of TP53 protein22276220
D013792ThalidomideThalidomide analog results in increased expression of TP53 mRNA20525221
C026995thallium acetatethallium acetate results in increased expression of TP53 protein15965099
C042172thallium nitrateEGF protein inhibits the reaction [thallium nitrate analog results in increased phosphorylation of TP53 protein]27412756
C042172thallium nitrateEGF protein inhibits the reaction [thallium nitrate results in increased phosphorylation of TP53 protein]27412756
C042172thallium nitratethallium nitrate analog results in decreased expression of and results in increased phosphorylation of TP53 protein27412756
C042172thallium nitratethallium nitrate results in increased phosphorylation of TP53 protein27412756
D019284Thapsigargincaffeic acid promotes the reaction [Thapsigargin results in decreased expression of TP53 mRNA]19442820
D019284ThapsigarginThapsigargin results in decreased expression of TP53 mRNA19442820
C056068theaflavintheaflavin results in increased expression of TP53 protein17499812
D013806TheophyllineIL4 protein inhibits the reaction [[Theophylline co-treated with Chlorambucil] results in increased expression of TP53]8822937
D013806Theophylline[Theophylline co-treated with Chlorambucil] results in increased expression of TP538822937
D013806TheophyllineTheophylline results in decreased expression of TP538822937
D013806TheophyllineTheophylline results in decreased expression of TP53 mRNA17522070
D013827ThiabendazoleThiabendazole results in increased expression of TP53 mRNA18539377
D013853ThioacetamideThioacetamide results in increased expression of TP53 mRNA17997003
D013853ThioacetamideThioacetamide results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein16937528
D013853ThioacetamideThioacetamide results in increased expression of TP53 mRNA23411599|2601163
D013853ThioacetamideThioacetamide results in increased expression of TP53 protein23411599
D008063Thioctic AcidThioctic Acid inhibits the reaction [Methotrexate results in increased expression of TP53 protein]19900424
C523062thio-dimethylarsinatethio-dimethylarsinate results in increased expression of TP53 mRNA27320638
D013866ThioguanineThioguanine results in increased activity of TP53 protein22010212
D013882Thiosemicarbazones[Thiosemicarbazones binds to Copper] which results in decreased activity of TP53 protein20931265
D013883ThiostreptonThiostrepton results in decreased expression of TP53 mRNA22321511
D013883ThiostreptonThiostrepton results in decreased expression of TP53 protein22321511
D013974ThyroxineThyroxine inhibits the reaction [resveratrol results in increased activity of TP53 protein]17174366
D013974Thyroxinetetraiodothyroacetic acid inhibits the reaction [Thyroxine affects the localization of TP53 protein modified form]17984113
D013974ThyroxineThyroxine affects the localization of TP53 protein modified form17984113
C003466thymoquinonethymoquinone results in increased expression of TP53 protein21609759
C027385tibolonetibolone results in decreased expression of TP53 protein16021059
C402769tipifarnibtipifarnib results in decreased expression of TP53 mRNA16403772
C049947tirapazaminetirapazamine results in increased expression of TP5315814660
C049947tirapazamineTP53 results in increased susceptibility to tirapazamine15814660
C009495titanium dioxidetitanium dioxide results in increased expression of TP5323111874
C009495titanium dioxidetitanium dioxide results in increased expression of TP53 mRNA19695317|2106727
C009495titanium dioxidetitanium dioxide results in increased expression of TP53 protein20362650
C009495titanium dioxidetitanium dioxide results in increased phosphorylation of TP53 protein20863874
D014028Tobacco Smoke Pollution3'-methoxy-4'-nitroflavone inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of TP53 mRNA]17070097
D014028Tobacco Smoke Pollution3'-methoxy-4'-nitroflavone inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of TP53 protein]17070097
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TP53 mRNA17070097|2740439
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TP53 protein17070097
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of TP53 mRNA27865774
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased mutagenesis of TP53 gene10824542
D024505TocopherolsTocopherols results in increased activity of TP53 protein15883045
D014044TolbutamideTolbutamide results in increased expression of TP53 mRNA16426753
D014050TolueneToluene results in increased phosphorylation of TP53 protein8076368
D014050TolueneToluene results in increased phosphorylation of and results in increased activity of TP53 protein9118908
D014050TolueneToluene results in increased phosphorylation of TP53 protein8076368
D019772TopotecanTopotecan results in increased activity of TP53 protein12698201
D019772TopotecanTopotecan results in increased expression of TP53 protein12698201|2003861
D019772TopotecanTP53 inhibits the reaction [Topotecan results in increased activity of CASP3 protein]19812371
D019772TopotecanTP53 inhibits the reaction [Topotecan results in increased cleavage of CASP2 protein]19812371
D019772TopotecanTP53 protein results in increased susceptibility to Topotecan22101337
D014108Tosylphenylalanyl Chloromethyl KetoneTosylphenylalanyl Chloromethyl Ketone results in decreased phosphorylation of and results in increased activity of TP53 protein12821135
D014108Tosylphenylalanyl Chloromethyl KetoneTP53 protein promotes the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased activity of CASP3 protein]12821135
D014108Tosylphenylalanyl Chloromethyl KetoneTP53 protein promotes the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased activity of CASP7 protein]12821135
D014108Tosylphenylalanyl Chloromethyl KetoneTP53 protein results in increased susceptibility to Tosylphenylalanyl Chloromethyl Ketone12821135
C496197trans-10,cis-12-conjugated linoleic acid"trans-10,cis-12-conjugated linoleic acid results in increased phosphorylation of and affects the localization of TP53 protein"15992797
D014212TretinoinTretinoin affects the expression of TP5316720286
D014212Tretinoin[Tretinoin co-treated with zoledronic acid] results in decreased expression of TP53 protein20349282
D014212TretinoinTretinoin inhibits the reaction [Cisplatin results in increased acetylation of TP53 protein]21532991
D014212TretinoinTretinoin inhibits the reaction [[Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of TP53 protein]17327230
D014212TretinoinTretinoin inhibits the reaction [geldanamycin affects the localization of TP53 protein]17293044
D014212TretinoinTretinoin results in decreased expression of TP53 protein16461808
D014212TretinoinTretinoin results in increased activity of TP53 protein15674351
D014212TretinoinTretinoin results in increased expression of TP53 mRNA16054129
D014212TretinoinTretinoin results in increased expression of TP53 protein15254726|1647392
D014212TretinoinTretinoin results in increased ubiquitination of and results in increased degradation of TP53 protein16740359
D014212Tretinoin"[Tretinoin results in increased uptake of Glucose] inhibits the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
D014212Tretinoinvorinostat inhibits the reaction [Tretinoin inhibits the reaction [Cisplatin results in increased acetylation of TP53 protein]]21532991
D014212TretinoinTretinoin results in decreased expression of TP53 protein17962954
C072782tri-(2-chloroisopropyl)phosphatetri-(2-chloroisopropyl)phosphate binds to TP53 gene25510514
C072782tri-(2-chloroisopropyl)phosphatetri-(2-chloroisopropyl)phosphate results in increased expression of TP53 mRNA25510514
C032910triadimefontriadimefon results in increased expression of TP53 mRNA24962053
C009524tributyl phosphatetributyl phosphate binds to TP53 protein24411723
C011559tributyltintributyltin results in decreased expression of TP53 protein26961604
C011559tributyltintributyltin results in increased expression of TP53 protein25743928
C447082tricarbonyldichlororuthenium (II) dimertricarbonyldichlororuthenium (II) dimer affects the expression of TP53 protein24211270
D014236TrichlorfonTrichlorfon results in increased expression of TP53 protein19631781
D014241TrichloroethyleneTrichloroethylene results in increased expression of TP53 protein12160929
C012589trichostatin Aanacardic acid inhibits the reaction [Genistein promotes the reaction [trichostatin A results in increased acetylation of TP53 protein]]26768552
C012589trichostatin AEP300 promotes the reaction [Genistein promotes the reaction [trichostatin A results in increased expression of TP53 mRNA]]26768552
C012589trichostatin AEP300 promotes the reaction [Genistein promotes the reaction [trichostatin A results in increased expression of TP53 protein]]26768552
C012589trichostatin AEP300 promotes the reaction [trichostatin A results in increased expression of TP53 protein]26768552
C012589trichostatin AEtoposide promotes the reaction [trichostatin A results in increased expression of TP53 protein]25699604
C012589trichostatin A[Genistein co-treated with trichostatin A] results in increased expression of TP53 protein22626855
C012589trichostatin AGenistein promotes the reaction [trichostatin A results in increased expression of and results in increased acetylation of TP53 protein]26768552
C012589trichostatin AGenistein promotes the reaction [trichostatin A results in increased expression of TP53 mRNA]26768552
C012589trichostatin Aleptomycin B inhibits the reaction [TP53 protein results in increased susceptibility to trichostatin A]16467109
C012589trichostatin Apifithrin inhibits the reaction [TP53 protein results in increased susceptibility to trichostatin A]16467109
C012589trichostatin ATP53 protein affects the reaction [trichostatin A results in increased expression of TP63 protein alternative form]20043870
C012589trichostatin ATP53 protein results in increased susceptibility to trichostatin A16467109
C012589trichostatin Atrichostatin A promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]25699604
C012589trichostatin Atrichostatin A results in decreased expression of TP53 mRNA19606018
C012589trichostatin Atrichostatin A results in decreased expression of TP53 protein15179185
C012589trichostatin Atrichostatin A results in decreased expression of TP53 protein mutant form15179185
C012589trichostatin Atrichostatin A results in increased acetylation of and results in increased activity of TP53 protein15964798
C012589trichostatin Atrichostatin A results in increased expression of and results in increased acetylation of TP53 protein26768552
C012589trichostatin Atrichostatin A results in increased expression of TP53 mRNA16865256|2676855
C012589trichostatin Atrichostatin A results in increased expression of TP53 protein25699604
C012589trichostatin Atrichostatin A results in decreased activity of TP53 protein16426753
C012589trichostatin Atrichostatin A results in decreased expression of TP53 mRNA23558232
D014266TrientineParaquat promotes the reaction [Trientine results in increased phosphorylation of TP53 protein]11369509
D014266TrientineTrientine results in increased expression of and results in increased activity of TP53 protein14513838
D014266TrientineTrientine results in increased phosphorylation of TP53 protein11369509
C009549triethyl phosphatetriethyl phosphate binds to TP53 protein24411723
C009549triethyl phosphatetriethyl phosphate binds to TP53 gene25510514
C011560triisopropyl phosphatetriisopropyl phosphate binds to TP53 gene25510514
C009475trimethylenediamine[Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of TP53 protein17327230
C009475trimethylenediamineTretinoin inhibits the reaction [[Copper binds to Isatin binds to trimethylenediamine] which results in increased expression of TP53 protein]17327230
C003715trimethyl phosphatetrimethyl phosphate binds to TP53 gene25510514
C040533trimethyltin chloridetrimethyltin chloride promotes the reaction [TP53 protein results in increased expression of BBC3 mRNA]19655806
C040533trimethyltin chloridetrimethyltin chloride promotes the reaction [TP53 protein results in increased expression of CDKN1A mRNA]19655806
C068051tripchlorolidetripchlorolide affects the reaction [TP53 protein affects the expression of BIRC5 mRNA]15916722
C068051tripchlorolidetripchlorolide results in increased expression of TP53 mRNA15916722
C005445triphenyl phosphatetriphenyl phosphate binds to and results in increased expression of TP53 protein25333763
C005445triphenyl phosphatetriphenyl phosphate results in increased expression of TP53 mRNA25333763
C005445triphenyl phosphatetriphenyl phosphate binds to TP53 gene25510514
C005445triphenyl phosphatetriphenyl phosphate results in increased expression of TP53 mRNA25510514
C030665triphenyltintriphenyltin results in increased expression of TP53 protein25743928
C050414tripterinetripterine results in increased expression of TP53 protein27374097
C050414tripterineUridine inhibits the reaction [tripterine results in increased expression of TP53 protein]27374097
C012085tris(2,3-dibromopropyl)phosphate"tris(2,3-dibromopropyl)phosphate results in increased expression of TP53 protein"9163691
C049232tris(2-ethylhexyl)phosphatetris(2-ethylhexyl)phosphate binds to TP53 gene25510514
C031324tris(chloroethyl)phosphatetris(chloroethyl)phosphate binds to TP53 protein24411723|2533376
C031324tris(chloroethyl)phosphatetris(chloroethyl)phosphate binds to TP53 gene25510514
D014317Tritolyl PhosphatesTritolyl Phosphates binds to TP53 gene25510514
C057693troglitazoneTP53 protein results in increased susceptibility to troglitazone12824901
C057693troglitazonetroglitazone promotes the reaction [TP53 protein results in increased expression of PRODH mRNA]16303758
C057693troglitazonetroglitazone results in decreased expression of TP53 mRNA19631733
C057693troglitazonetroglitazone results in increased expression of TP53 mRNA17143939|1963173
C057693troglitazonetroglitazone results in increased expression of TP53 protein12595159|1282490
C057693troglitazonetroglitazone results in increased expression of TP53 mRNA11068018
C057693troglitazonetroglitazone results in increased expression of TP53 protein11068018|1576704
C046243tryptanthrinetryptanthrine results in decreased expression of and results in increased degradation of TP53 protein17482571
C002802tungsten carbide[tungsten carbide co-treated with Cobalt] results in increased expression of and results in increased stability of TP53 protein23052192
D014415TunicamycinTunicamycin results in increased expression of TP53 protein20886113
D014415TunicamycinTunicamycin promotes the reaction [Capsaicin results in increased degradation of TP53 protein]19699254
D014415TunicamycinHR protein inhibits the reaction [Tunicamycin results in increased expression of TP53 protein]20886113
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [sodium arsenite results in increased expression of TP53 protein]15734884
C098214tyrphostin AG825tyrphostin AG825 inhibits the reaction [sodium arsenite results in increased expression of TP53 protein]15734884
C113580U 0126U 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of TP53 mRNA]12710931
C113580U 0126"[U 0126 co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in increased expression of TP53 protein"22101421
C113580U 0126U 0126 inhibits the reaction [[Cisplatin co-treated with chrysin] affects the localization of TP53 protein]25770930
C113580U 0126U 0126 inhibits the reaction [[Cisplatin co-treated with chrysin] results in increased phosphorylation of TP53 protein]25770930
C113580U 0126U 0126 inhibits the reaction [sodium arsenite results in decreased phosphorylation of TP53 protein]22706169
C113580U 0126U 0126 results in increased expression of TP53 protein22101421
C113580U 0126U 0126 inhibits the reaction [Calcimycin results in increased expression of TP53 protein]16000378
C113580U 0126"U 0126 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein]"16005925
C113580U 0126U 0126 inhibits the reaction [Doxorubicin results in increased expression of and results in increased localization of TP53 protein modified form]18775851
C113580U 0126U 0126 inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased localization of TP53 protein]18775851
C000602704UF010 compoundEtoposide promotes the reaction [UF010 compound results in increased expression of TP53 protein]25699604
C000602704UF010 compoundUF010 compound promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]25699604
C000602704UF010 compoundUF010 compound results in increased expression of TP53 protein25699604
C561310UNC 0638UNC 0638 inhibits the reaction [EHMT1 protein results in increased methylation of TP53 protein]21780790
C561310UNC 0638UNC 0638 inhibits the reaction [EHMT2 protein results in increased methylation of TP53 protein]21780790
D014498UracilTP53 protein affects the susceptibility to [Uracil co-treated with Tegafur]15182437
D014529UridineUridine inhibits the reaction [tripterine results in increased expression of TP53 protein]27374097
D014580Ursodeoxycholic AcidMDM2 mutant form inhibits the reaction [Ursodeoxycholic Acid results in increased ubiquitination of TP53 protein]20807506
D014580Ursodeoxycholic AcidTP53 mutant form inhibits the reaction [[oxaliplatin co-treated with Ursodeoxycholic Acid] results in increased activity of CASP3 protein]19728331
D014580Ursodeoxycholic AcidTP53 mutant form inhibits the reaction [[oxaliplatin co-treated with Ursodeoxycholic Acid] results in increased activity of CASP8 protein]19728331
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased ubiquitination of TP53 protein20807506
D014580Ursodeoxycholic AcidMDM2 mutant form inhibits the reaction [Ursodeoxycholic Acid affects the localization of TP53 protein]17881359
D014580Ursodeoxycholic AcidNR3C1 mutant form inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein]]15222754
D014580Ursodeoxycholic AcidNR3C2 mutant form inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein]]15222754
D014580Ursodeoxycholic AcidTP53 protein affects the susceptibility to Ursodeoxycholic Acid17431217
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid affects the localization of and results in decreased phosphorylation of TP53 protein17881359
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid affects the localization of TP53 protein17881359
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in increased expression of TP53 mRNA]20137712
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [E2F1 protein results in increased expression of TP53 protein]14514686
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein]14514686|1522275
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [TP53 protein results in increased expression of and results in increased localization of BAX protein]17881359
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [TP53 protein results in increased expression of BAX mRNA]17881359
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [TP53 protein results in increased expression of BAX protein]14514686|1788135
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid promotes the reaction [TP53 protein binds to MDM2 protein]17881359
D014580Ursodeoxycholic Acid[Ursodeoxycholic Acid promotes the reaction [TP53 protein binds to MDM2 protein]] which results in increased degradation of TP53 protein17881359
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased ubiquitination of and results in increased degradation of TP53 protein20807506
C073339usnic acidusnic acid results in decreased expression of TP53 protein22285236
C073339usnic acidusnic acid results in increased expression of TP53 protein22285236
C108850V 10367V 10367 inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]12642403
D014635Valproic Acid[Hydralazine co-treated with Valproic Acid] results in increased expression of TP53 mRNA17183730
D014635Valproic AcidValproic Acid affects the expression of TP53 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of TP53 mRNA28001369
D014635Valproic AcidValproic Acid results in increased expression of TP53 mRNA22580532|2281401
D014635Valproic AcidValproic Acid results in increased methylation of TP53 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of TP53 protein23562654
D014639VanadiumVanadium results in increased activity of TP53 protein19000753
D014639Vanadium"Vanadium inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of TP53 protein]"18155637
D014639VanadiumVanadium promotes the reaction [2-Acetylaminofluorene results in increased expression of TP53 protein]15565650
D017968Vanadium CompoundsVanadium Compounds results in increased expression of and results in increased phosphorylation of TP53 protein26391003
C100058vanillinvanillin results in decreased expression of TP53 mRNA17178418
D001335Vehicle EmissionsVehicle Emissions analog results in increased mutagenesis of TP53 gene10682588
D001335Vehicle Emissions[[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of MDM2 protein] which results in increased expression of TP53 protein28013216
D001335Vehicle Emissions[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TP53 protein28013216
D001335Vehicle EmissionsVehicle Emissions results in increased expression of TP53 mRNA23454527
D001335Vehicle EmissionsVehicle Emissions analog results in increased phosphorylation of TP53 protein25500124
D001335Vehicle EmissionsVehicle Emissions results in increased expression of TP53 mRNA24216475
D014747VinblastineTP53 protein affects the reaction [Vinblastine results in increased phosphorylation of JUN protein]12221076
D014747VinblastineTP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein]12221076
D014747VinblastineTP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK9 protein]12221076
D014750Vincristine[Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of TP53 protein9815696
D014750VincristineTP53 protein results in increased susceptibility to Vincristine14704126
D014750VincristineVincristine results in increased activity of TP53 protein22010212
D014750VincristineVincristine results in increased expression of TP53 protein12082016|1513105
D014750VincristineVincristine results in increased glutathionylation of TP53 protein17555331
D014752Vinyl ChlorideCYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]12705718
D014752Vinyl ChlorideCYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]12010862|1738490
D014752Vinyl ChlorideGSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]16097394
D014752Vinyl ChlorideGSTT1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]16097394
D014752Vinyl ChlorideTP53 gene SNP results in increased susceptibility to Vinyl Chloride18226366
D014752Vinyl ChlorideTP53 polymorphism affects the susceptibility to Vinyl Chloride24464562
D014752Vinyl ChlorideVinyl Chloride results in decreased expression of TP53 mRNA22076037
D014752Vinyl ChlorideVinyl Chloride results in increased expression of TP53 protein12670519|1497906
D014752Vinyl ChlorideVinyl Chloride results in increased expression of TP53 protein mutant form16474264
D014752Vinyl ChlorideVinyl Chloride results in increased mutagenesis of TP53 gene12010862|1267051
D014752Vinyl ChlorideXRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]16097394
D014752Vinyl ChlorideXRCC1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]14602524
D014752Vinyl ChlorideXRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]12010862|1688159
D014757Viper VenomsViper Venoms results in increased expression of and affects the localization of TP53 protein27613483
D012256RiboflavinRiboflavin results in increased expression of TP53 protein12654180
D009536Niacinamide[Berberine co-treated with Niacinamide] results in increased expression of and results in increased acetylation of TP53 protein26712469
D009536NiacinamideNiacinamide inhibits the reaction [tert-Butylhydroperoxide results in increased expression of TP53 protein]12782109
D009536Niacinamide[Niacinamide results in decreased activity of SIRT1 protein] promotes the reaction [Hydrogen Peroxide results in increased acetylation of TP53 protein]18681908
D009536NiacinamideNiacinamide results in decreased activity of [SIRT1 protein results in decreased acetylation of TP53 protein]18482975
D009536NiacinamideNiacinamide results in decreased expression of TP53 protein12782109
D009536NiacinamideNiacinamide results in increased phosphorylation of and results in increased acetylation of TP53 protein26712469
D014810Vitamin E[Selenium co-treated with Vitamin E] results in increased expression of TP53 mRNA19244175
D014810Vitamin EVitamin E inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased activity of TP53 protein]24664296
D014810Vitamin EVitamin E inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of TP53 protein]15837074
D014810Vitamin EVitamin E results in increased expression of TP53 mRNA19244175
D014810Vitamin E[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 mRNA]21628957
D014810Vitamin EVitamin E inhibits the reaction [cypermethrin results in increased expression of TP53 mRNA]24759048
D014810Vitamin EVitamin E inhibits the reaction [decamethrin results in increased expression of TP53 mRNA]25439240
D024483Vitamin K 3EUK-134 inhibits the reaction [Vitamin K 3 results in increased expression of TP53 protein]25005833
D024483Vitamin K 3SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of TP53 protein]19082730
D024483Vitamin K 3[sodium arsenite co-treated with Vitamin K 3] results in increased phosphorylation of TP53 protein19082730
D024483Vitamin K 3Vitamin K 3 results in increased expression of TP53 protein21533478|2500583
C111237vorinostat[vorinostat co-treated with Bortezomib] results in increased expression of TP53 protein17351739
C111237vorinostatvorinostat inhibits the reaction [Tretinoin inhibits the reaction [Cisplatin results in increased acetylation of TP53 protein]]21532991
C111237vorinostatvorinostat promotes the reaction [PML protein binds to TP53 protein]19631782
C111237vorinostatvorinostat promotes the reaction [resveratrol results in increased acetylation of TP53 protein]19810103
C111237vorinostatvorinostat promotes the reaction [TP53 protein binds to PML protein binds to CREBBP protein]19631782
C111237vorinostatvorinostat results in increased acetylation of TP53 protein19084294
C111237vorinostatvorinostat results in increased expression of TP53 protein17351739
D014859WarfarinWarfarin results in increased degradation of TP53 protein14634213
D014859WarfarinWarfarin affects the expression of TP53 protein12872399
D014874Water Pollutants, Chemical"Water Pollutants, Chemical results in increased expression of TP53 mRNA"22326570|2306306
C009684withaferin Awithaferin A binds to TP53 protein22973447
C009684withaferin Awithaferin A inhibits the reaction [HSPA9 protein binds to TP53 protein]22973447
C009684withaferin A[withaferin A inhibits the reaction [HSPA9 protein binds to TP53 protein]] which affects the localization of and results in increased activity of TP53 protein22973447
C009684withaferin Awithaferin A results in increased expression of TP53 mRNA22973447
C085514wogoninwogonin results in increased expression of TP53 protein21457722
C009687wortmanninwortmannin inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of TP53 protein]19111594
C009687wortmannin"wortmannin inhibits the reaction [3,3'-diindolylmethane results in increased phosphorylation of TP53 protein]"22290291
C009687wortmannin"wortmannin inhibits the reaction [Asbestos, Serpentine results in increased expression of TP53 protein]"12676607
C009687wortmannin"wortmannin inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of TP53 protein]"12676607
C009687wortmanninwortmannin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of TP53 protein]15837074
C009687wortmanninwortmannin inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]]15489221
C009687wortmanninwortmannin inhibits the reaction [Mustard Gas results in increased expression of TP53 protein]22119920
C009687wortmanninwortmannin inhibits the reaction [Mustard Gas results in increased phosphorylation of TP53 protein]22119920
C009687wortmanninwortmannin inhibits the reaction [Nitric Oxide results in increased phosphorylation of TP53 protein]16024610
C009687wortmanninwortmannin inhibits the reaction [resveratrol results in increased phosphorylation of TP53 protein]17534123
C009687wortmanninwortmannin inhibits the reaction [spermine nitric oxide complex results in increased phosphorylation of TP53 protein]16024610
C009687wortmanninwortmannin promotes the reaction [arsenic disulfide results in increased expression of and results in increased phosphorylation of TP53 protein]18298901
C009687wortmanninwortmannin results in decreased phosphorylation of and results in decreased expression of TP53 protein22290291
C009687wortmanninwortmannin results in decreased phosphorylation of TP53 protein22119920
C009687wortmanninwortmannin inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 protein]11751435
C009687wortmanninwortmannin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of TP53 protein]11751435
C451735WP 744WP 744 results in increased expression of TP53 protein15555623
C022186xanthatinTP53 protein promotes the reaction [xanthatin results in decreased expression of CDC25C protein modified form]29074359
C022186xanthatinTP53 protein promotes the reaction [xanthatin results in decreased phosphorylation of CHEK1 protein]29074359
C022186xanthatinTP53 protein promotes the reaction [xanthatin results in decreased stability of CDC25C protein]29074359
C022186xanthatinTP53 protein results in increased susceptibility to xanthatin29074359
C104536xanthohumolxanthohumol results in increased expression of TP5326297991|2731702
C104536xanthohumolxanthohumol results in increased expression of TP53 mRNA23085367
C104536xanthohumolxanthohumol results in increased expression of TP53 protein23085367
C000607970XI-006XI-006 inhibits the reaction [formononetin results in decreased expression of TP53 protein]28414026
C530084xinmaitongxinmaitong affects the expression of TP53 protein12872399
C118180XK 469XK 469 results in increased expression of TP53 protein11774253
C108830Y 27632TP53 protein affects the susceptibility to Y 2763220878077
C108830Y 27632TP53 protein promotes the reaction [Y 27632 results in decreased susceptibility to Cisplatin]20878077
C108830Y 27632Y 27632 inhibits the reaction [Cisplatin results in increased expression of TP53 mRNA]20878077
C108830Y 27632Y 27632 results in decreased expression of TP53 mRNA20878077
C108830Y 27632Y 27632 results in increased expression of TP53 protein11839765
C105427ZeocinZeocin results in increased stability of and results in increased expression of TP53 protein11741290
D015215ZidovudineZidovudine results in increased expression of TP53 protein16797627
D015032ZincTP53 protein inhibits the reaction [Zinc results in increased phosphorylation of MAPK1 protein]15880691
D015032ZincTP53 protein inhibits the reaction [Zinc results in increased phosphorylation of MAPK3 protein]15880691
D015032ZincTP53 protein promotes the reaction [Zinc results in increased abundance of Reactive Oxygen Species]15880691
D015032ZincTP53 protein results in increased susceptibility to Zinc15880691
D015032ZincZinc affects the expression of TP53 protein16636310
D015032ZincZinc affects the folding of TP53 protein16768444
D015032ZincZinc affects the localization of TP53 protein12107073
D015032ZincZinc binds to TP53 protein17327663
D015032ZincZinc deficiency results in increased expression of TP53 mRNA18356318
D015032ZincZinc results in increased expression of TP53 protein12888634|1588069
D015032Zinc[SLC30A10 protein affects the abundance of Zinc] which affects the expression of TP53 protein22427991
D015032Zinc[SLC30A3 protein affects the abundance of Zinc] which affects the expression of TP53 protein22427991
D015032ZincZinc binds to TP53 protein16909841
D019345Zinc AcetateAcetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
D019345Zinc Acetate[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein20530418
D019345Zinc Acetatebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
D019345Zinc Acetatenutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]20530418
C016837zinc chloridezinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]19714248
D017967Zinc CompoundsZinc Compounds results in increased expression of TP53 mRNA24035972
D017967Zinc CompoundsZinc Compounds results in increased expression of TP53 protein24035972
D015034Zinc OxideZinc Oxide affects the expression of TP53 protein28648595
D015034Zinc OxideZinc Oxide results in increased phosphorylation of and results in increased expression of TP53 protein21903158
C017803zinc protoporphyrin[zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [cobaltiprotoporphyrin results in increased expression of TP53 protein]18042465
C017803zinc protoporphyrinzinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in decreased expression of TP53 protein]20357190
D019287Zinc Sulfate"[Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]"18951928
D019287Zinc SulfateAcetylcysteine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]18951928
D019287Zinc Sulfatebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]18951928
D019287Zinc Sulfate"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]"18951928
D019287Zinc Sulfate[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein18951928
D019287Zinc SulfateZinc Sulfate inhibits the reaction [prolinedithiocarbamate results in increased phosphorylation of TP53 protein]18951928
D019287Zinc SulfateZinc Sulfate results in increased phosphorylation of and results in increased expression of TP53 protein15001399
C097270ZM 241385ZM 241385 inhibits the reaction [cordycepin results in increased phosphorylation of and results in increased expression of TP53 protein]24704558
C088658zoledronic acid[Tretinoin co-treated with zoledronic acid] results in decreased expression of TP53 protein20349282
C088658zoledronic acidzoledronic acid affects the activity of TP53 protein25596134

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding-IDA24289924  
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding-ISS-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-IDA17310983  24652652  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0000990transcription factor activity, core RNA polymerase binding-IDA15314173  
GO:0001046core promoter sequence-specific DNA binding-IDA23629966  
GO:0001074transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly-IDA24289924  
GO:0001085RNA polymerase II transcription factor binding-IPI18549481  
GO:0001094TFIID-class transcription factor binding-IPI24289924  
GO:0001228transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding-IDA17146433  
GO:0002020protease binding-IPI11923872  
GO:0002039p53 binding-IPI25417702  
GO:0003677DNA binding-IDA15358771  
GO:0003677DNA binding-IMP2144364  15629713  
GO:0003682chromatin binding-IDA16322561  17599062  
GO:0003700DNA-binding transcription factor activity-IDA7587074  18549481  
GO:0003700DNA-binding transcription factor activity-IMP16479015  
GO:0003730mRNA 3'-UTR binding-IDA16213212  
GO:0005507copper ion binding-IDA7824276  
GO:0005515protein binding-IPI1465435  7663514  7799929  8207801  8344494  8388547  
8675009  8875926  8875929  9050995  9188558  9194564  
9194565  9380510  9472015  9529249  9807817  9827557  
9926942  10196247  10226625  10518217  10597287  10608892  
10618715  10724175  10823891  11080164  11146555  11178989  
11359905  11388671  11427532  11571640  11672523  11684014  
11706030  11877378  11907332  11923872  11950834  12006491  
12080348  12397362  12534345  12620801  12667443  12702766  
12730672  12750254  12898523  12915590  14557665  14627987  
14704432  14744935  14963330  14976264  14985081  15044383  
15068796  15103385  15133049  15144954  15205477  15254196  
15310821  15327968  15364927  15525938  15542844  15580310  
15604276  15660129  15710329  15710382  15735003  15735006  
15782130  15848166  15855171  15862297  15896780  15907477  
15916963  15960975  15989956  16003391  16151013  16169070  
16189514  16212962  16227626  16319068  16322561  16376338  
16376884  16377624  16402859  16415881  16432196  16442532  
16474402  16493710  16601686  16611888  16616141  16690937  
16713569  16732283  16753148  16845383  16847267  16951253  
16959611  17080083  17098746  17108971  17139261  17145718  
17159902  17170702  17184779  17237821  17245430  17254968  
17268548  17274640  17290220  17298945  17310983  17317671  
17347673  17438265  17470788  17482142  17568776  17612295  
17662718  17707234  17719541  17719542  17805299  17875722  
17904127  17906639  17964266  18087040  18172499  18230339  
18235501  18235502  18275817  18309296  18316739  18354501  
18388957  18391200  18485870  18504427  18510931  18566590  
18624398  18656471  18695251  18812399  18833288  18952844  
18977328  19008854  19043414  19098711  19151705  19166840  
19196987  19217391  19234109  19255450  19339993  19345189  
19411066  19433796  19483087  19508870  19521340  19536131  
19556538  19619542  19626115  19651603  19656744  19680552  
19684601  19740107  19798103  19805293  19833129  19857493  
19883646  19933256  20075864  20096447  20118233  20123734  
20124405  20134482  20153329  20159018  20167603  20173098  
20206173  20227041  20228809  20385133  20421506  20452352  
20515689  20534433  20562916  20591429  20622899  20660729  
20705607  20708156  20713054  20818423  20864041  20959462  
21057547  21078964  21081126  21130767  21132010  21170034  
21170087  21245319  21317932  21390126  21397192  21423215  
21460856  21471221  21513714  21625211  21726810  21741598  
21782458  21821029  21831840  21857681  21892170  21900206  
21952639  21988832  22056774  22085928  22103682  22124327  
22265415  22340593  22451927  22499945  22510990  22522597  
22575647  22653443  22659184  22723347  22726440  22761572  
22810585  22810586  22819825  22945289  22975381  23010591  
23063560  23092970  23320542  23431171  23576507  23623661  
23734815  23752197  23776060  23870121  24207125  24219989  
24380853  24449765  24492002  24667498  24814347  25241761  
25314079  25402006  25422469  25579814  25591766  25609649  
25651062  25670079  25837623  26302407  26331536  26789255  
27107012  27323408  27605672  29187402  29340707  
GO:0005524ATP binding-IDA8183576  
GO:0008134transcription factor binding-IPI15053879  15705871  19505873  
GO:0008270zinc ion binding-TAS10065153  
GO:0019899enzyme binding-IPI7663514  10666337  11672523  11781842  15044383  15577914  
17805299  20173098  
GO:0019901protein kinase binding-IPI11546806  21317932  
GO:0019903protein phosphatase binding-IPI20562916  
GO:0030971receptor tyrosine kinase binding-IPI23027130  
GO:0031625ubiquitin protein ligase binding-IPI8875929  9529249  10415337  17121812  18382127  
GO:0035035histone acetyltransferase binding-IPI9194565  10518217  
GO:0042802identical protein binding-IMP15629713  
GO:0042802identical protein binding-IPI14985081  16291740  16461914  17612295  17620598  18087040  
19339993  19667193  20004160  20159469  20364130  21178074  
21522129  21988832  22653443  22972749  25402006  25609649  
GO:0042826histone deacetylase binding-IPI23629966  
GO:0043621protein self-association-IPI14985081  
GO:0044212transcription regulatory region DNA binding-IDA15710329  17996705  
GO:0046982protein heterodimerization activity-IPI10837489  
GO:0047485protein N-terminus binding-IPI11861836  
GO:0051087chaperone binding-IPI15358771  18086682  
GO:0051721protein phosphatase 2A binding-IPI17245430  
GO:0097718disordered domain specific binding-IPI15629713  
GO:1990841promoter-specific chromatin binding-IDA24356969  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-ISS19749791  
GO:0000733DNA strand renaturation-IDA8183576  
GO:0006284base-excision repair-TAS15116721  
GO:0006289nucleotide-excision repair-IMP7663514  
GO:0006355regulation of transcription, DNA-templated-IDA7587074  
GO:0006355regulation of transcription, DNA-templated-IMP25417702  
GO:0006914autophagy-IMP23629966  
GO:0006974cellular response to DNA damage stimulus-IDA14744935  15710329  17938203  
GO:0006974cellular response to DNA damage stimulus-IMP24356969  
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-IMP16213212  
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-TAS-  
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-IDA16213212  
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-IMP7958916  16479015  
GO:0006983ER overload response-IDA14744935  
GO:0007050cell cycle arrest-IDA15149599  
GO:0007050cell cycle arrest-IMP7958916  10962037  
GO:0007265Ras protein signal transduction-IEP9054499  
GO:0007275multicellular organism development-IMP10065150  
GO:0007569cell aging-IMP12080348  
GO:0008104protein localization-IDA16507995  
GO:0008283cell proliferation-TAS10065150  
GO:0008285negative regulation of cell proliferation-IDA22783376  
GO:0008285negative regulation of cell proliferation-IMP12730672  
GO:0008285negative regulation of cell proliferation-ISS-  
GO:0008340determination of adult lifespan-ISS-  
GO:0009299mRNA transcription-IMP16479015  
GO:0010332response to gamma radiation-IMP7958916  
GO:0010628positive regulation of gene expression-IDA15314173  20332243  
GO:0010628positive regulation of gene expression-IMP19160485  
GO:0010628positive regulation of gene expression-ISS-  
GO:0016032viral process-IMP22574148  
GO:0016579protein deubiquitination-TAS-  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0030154cell differentiation-TAS10065150  
GO:0030308negative regulation of cell growth-IMP8986812  
GO:0030330DNA damage response, signal transduction by p53 class mediator-IDA15149599  
GO:0030330DNA damage response, signal transduction by p53 class mediator-IMP20160708  
GO:0031497chromatin assembly-IDA16322561  
GO:0031571mitotic G1 DNA damage checkpoint-IMP7958916  
GO:0032461positive regulation of protein oligomerization-IDA12667443  
GO:0034644cellular response to UV-IDA16213212  23629966  
GO:0035690cellular response to drug-IEP20810912  
GO:0042149cellular response to glucose starvation-IDA14744935  21471221  
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-IDA14654789  14744935  17403783  
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-IMP16213212  
GO:0042981regulation of apoptotic process-IDA14744935  
GO:0042981regulation of apoptotic process-TAS-  
GO:0043065positive regulation of apoptotic process-IDA12667443  15565177  20959462  
GO:0043066negative regulation of apoptotic process-IMP20124405  
GO:0043153entrainment of circadian clock by photoperiod-ISS-  
GO:0045892negative regulation of transcription, DNA-templated-IDA24051492  
GO:0045892negative regulation of transcription, DNA-templated-IMP23629966  
GO:0045892negative regulation of transcription, DNA-templated-ISS19749791  
GO:0045893positive regulation of transcription, DNA-templated-IDA16322561  17403783  18549481  20378837  
GO:0045893positive regulation of transcription, DNA-templated-IMP20096447  
GO:0045899positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-IDA24289924  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA11672523  17310983  17599062  18549481  20959462  24652652  
GO:0045944positive regulation of transcription by RNA polymerase II-IGI16061649  
GO:0045944positive regulation of transcription by RNA polymerase II-IMP17146433  24356969  
GO:0046677response to antibiotic-IEP20810912  
GO:0046827positive regulation of protein export from nucleus-TAS-  
GO:0046902regulation of mitochondrial membrane permeability-TAS15116721  
GO:0048147negative regulation of fibroblast proliferation-IMP10962037  
GO:0048512circadian behavior-ISS-  
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation-ISS19749791  
GO:0051097negative regulation of helicase activity-TAS7663514  
GO:0051123RNA polymerase II transcriptional preinitiation complex assembly-IEA-  
GO:0051262protein tetramerization-TAS15116721  
GO:0051289protein homotetramerization-IMP15629713  
GO:0051974negative regulation of telomerase activity-IDA10597287  
GO:0065003protein-containing complex assembly-IDA12915590  
GO:0070245positive regulation of thymocyte apoptotic process-ISS-  
GO:0071158positive regulation of cell cycle arrest-IDA15314173  
GO:0071158positive regulation of cell cycle arrest-IMP21471221  
GO:0071456cellular response to hypoxia-IEP20810912  
GO:0071479cellular response to ionizing radiation-IMP20160708  
GO:0071480cellular response to gamma radiation-IDA16213212  
GO:0072331signal transduction by p53 class mediator-IDA15314173  
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator-IMP12172011  16322561  17310983  
GO:0072717cellular response to actinomycin D-IDA15314173  
GO:0090200positive regulation of release of cytochrome c from mitochondria-IDA12667443  14963330  
GO:0090399replicative senescence-IMP19951988  
GO:0090403oxidative stress-induced premature senescence-IMP19951988  
GO:0097193intrinsic apoptotic signaling pathway-TAS16462759  
GO:0097252oligodendrocyte apoptotic process-IDA7720704  
GO:1900119positive regulation of execution phase of apoptosis-IMP14985081  
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-TAS-  
GO:1901796regulation of signal transduction by p53 class mediator-TAS-  
GO:1902749regulation of cell cycle G2/M phase transition-TAS-  
GO:1902895positive regulation of pri-miRNA transcription by RNA polymerase II-IDA20546595  
GO:1990440positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-ISS-  
GO:2000379positive regulation of reactive oxygen species metabolic process-IMP20160708  
GO:2001244positive regulation of intrinsic apoptotic signaling pathway-IMP14963330  
GO ID GO Term Qualifier Evidence PubMed
GO:0000790nuclear chromatin-IDA15710329  17805299  22521434  23629966  24289924  
GO:0005622intracellular-IDA16213212  
GO:0005634nucleus-IDA7720704  14744935  14963330  16322561  16507995  17403783  18756595  19234109  20096447  20810912  24101517  24289924  
GO:0005634nucleus-IMP16479015  
GO:0005654nucleoplasm-IDA11080164  12915590  
GO:0005654nucleoplasm-TAS-  
GO:0005669transcription factor TFIID complexcolocalizes_withIDA15053879  
GO:0005730nucleolus-IDA12080348  
GO:0005737cytoplasm-IDA7720704  14744935  16131611  20096447  20810912  23629966  
GO:0005737cytoplasm-IMP16479015  
GO:0005739mitochondrion-IDA12667443  24101517  
GO:0005759mitochondrial matrix-IEA-  
GO:0005783endoplasmic reticulum-IEA-  
GO:0005829cytosol-IDA14963330  24101517  
GO:0005829cytosol-TAS-  
GO:0016363nuclear matrix-IDA11080164  
GO:0016604nuclear bodycolocalizes_withIDA10360174  
GO:0016605PML body-IDA12006491  22869143  
GO:0032991protein-containing complex-IDA9529249  17310983  
GO:0032991protein-containing complex-IMP15629713  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
hsa04110Cell cycle
hsa04115p53 signaling pathway
hsa04210Apoptosis
hsa04310Wnt signaling pathway
hsa04722Neurotrophin signaling pathway
hsa05014Amyotrophic lateral sclerosis (ALS)
hsa05016Huntington's disease
hsa05160Hepatitis C
hsa05200Pathways in cancer
hsa05210Colorectal cancer
hsa05212Pancreatic cancer
hsa05213Endometrial cancer
hsa05214Glioma
hsa05215Prostate cancer
hsa05216Thyroid cancer
hsa05217Basal cell carcinoma
hsa05218Melanoma
hsa05219Bladder cancer
hsa05220Chronic myeloid leukemia
hsa05222Small cell lung cancer
hsa05223Non-small cell lung cancer
Reactome ID Reactome Term Evidence
R-HSA-109581ApoptosisTAS
R-HSA-109582HemostasisIEA
R-HSA-109606Intrinsic Pathway for ApoptosisTAS
R-HSA-111448Activation of NOXA and translocation to mitochondriaTAS
R-HSA-114452Activation of BH3-only proteinsTAS
R-HSA-1257604PIP3 activates AKT signalingTAS
R-HSA-1257604PIP3 activates AKT signalingIEA
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-139915Activation of PUMA and translocation to mitochondriaTAS
R-HSA-157118Signaling by NOTCHTAS
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-1640170Cell CycleTAS
R-HSA-168256Immune SystemTAS
R-HSA-1912408Pre-NOTCH Transcription and TranslationTAS
R-HSA-1912422Pre-NOTCH Expression and ProcessingTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-2262752Cellular responses to stressTAS
R-HSA-2559580Oxidative Stress Induced SenescenceTAS
R-HSA-2559583Cellular SenescenceTAS
R-HSA-2559584Formation of Senescence-Associated Heterochromatin Foci (SAHF)TAS
R-HSA-2559585Oncogene Induced SenescenceTAS
R-HSA-2559586DNA Damage/Telomere Stress Induced SenescenceTAS
R-HSA-2990846SUMOylationTAS
R-HSA-3108232SUMO E3 ligases SUMOylate target proteinsTAS
R-HSA-3232118SUMOylation of transcription factorsTAS
R-HSA-349425Autodegradation of the E3 ubiquitin ligase COP1TAS
R-HSA-3700989Transcriptional Regulation by TP53TAS
R-HSA-390466Chaperonin-mediated protein foldingIEA
R-HSA-390471Association of TriC/CCT with target proteins during biosynthesisIEA
R-HSA-391251Protein foldingIEA
R-HSA-392499Metabolism of proteinsTAS
R-HSA-392499Metabolism of proteinsIEA
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-453274Mitotic G2-G2/M phasesTAS
R-HSA-5357801Programmed Cell DeathTAS
R-HSA-5628897TP53 Regulates Metabolic GenesTAS
R-HSA-5633007Regulation of TP53 ActivityTAS
R-HSA-5633008TP53 Regulates Transcription of Cell Death GenesTAS
R-HSA-5688426DeubiquitinationTAS
R-HSA-5689880Ub-specific processing proteasesTAS
R-HSA-5689896Ovarian tumor domain proteasesTAS
R-HSA-5693532DNA Double-Strand Break RepairTAS
R-HSA-5693565Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaksTAS
R-HSA-5693606DNA Double Strand Break ResponseTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6785807Interleukin-4 and 13 signalingTAS
R-HSA-6791312TP53 Regulates Transcription of Cell Cycle GenesTAS
R-HSA-6796648TP53 Regulates Transcription of DNA Repair GenesTAS
R-HSA-6803204TP53 Regulates Transcription of Genes Involved in Cytochrome C ReleaseTAS
R-HSA-6803205TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertainTAS
R-HSA-6803207TP53 Regulates Transcription of Caspase Activators and CaspasesTAS
R-HSA-6803211TP53 Regulates Transcription of Death Receptors and LigandsTAS
R-HSA-6804114TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle ArrestTAS
R-HSA-6804115TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertainTAS
R-HSA-6804116TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle ArrestTAS
R-HSA-6804754Regulation of TP53 ExpressionTAS
R-HSA-6804756Regulation of TP53 Activity through PhosphorylationTAS
R-HSA-6804757Regulation of TP53 DegradationTAS
R-HSA-6804758Regulation of TP53 Activity through AcetylationTAS
R-HSA-6804759Regulation of TP53 Activity through Association with Co-factorsTAS
R-HSA-6804760Regulation of TP53 Activity through MethylationTAS
R-HSA-6806003Regulation of TP53 Expression and DegradationTAS
R-HSA-6807070PTEN RegulationTAS
R-HSA-6807070PTEN RegulationIEA
R-HSA-6811555PI5P Regulates TP53 AcetylationTAS
R-HSA-69275G2/M TransitionTAS
R-HSA-69278Cell Cycle, MitoticTAS
R-HSA-69473G2/M DNA damage checkpointTAS
R-HSA-69481G2/M CheckpointsTAS
R-HSA-69541Stabilization of p53TAS
R-HSA-69560Transcriptional activation of p53 responsive genes TAS
R-HSA-69563p53-Dependent G1 DNA Damage ResponseTAS
R-HSA-69580p53-Dependent G1/S DNA damage checkpointTAS
R-HSA-69615G1/S DNA Damage CheckpointsTAS
R-HSA-69620Cell Cycle CheckpointsTAS
R-HSA-69895Transcriptional activation of cell cycle inhibitor p21 TAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-73894DNA RepairTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8852276The role of GTSE1 in G2/M progression after G2 checkpointTAS
R-HSA-8878159Transcriptional regulation by RUNX3TAS
R-HSA-8941855RUNX3 regulates CDKN1A transcriptionTAS
R-HSA-8943724Regulation of PTEN gene transcriptionTAS
R-HSA-8943724Regulation of PTEN gene transcriptionIEA
R-HSA-8953897Cellular responses to external stimuliTAS
R-HSA-9006925Intracellular signaling by second messengersTAS
R-HSA-9006925Intracellular signaling by second messengersIEA
R-HSA-983231Factors involved in megakaryocyte development and platelet productionIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23435014Differential mutation profiles and similar intronic TP53 polymorphisms in asbestos-related lung cancer and pleural mesothelioma. (2013 May)Andujar PMutagenesis
7657384TP53 and RAS mutations in metachronous tumors from patients with cancer of the upper aerodigestive tract. (1995 Aug 22)Yang HKInt J Cancer
23384026Serum p53 antibody detection in patients with impaired lung function. (2013 Feb 6)Mattioni MBMC Cancer
17208332An increased lung cancer risk associated with codon 72 polymorphism in the TP53 gene and human papillomavirus infection in Mazandaran province, Iran. (2007 May)Nadji SALung Cancer
25034526Lung cancer risk in relation to TP53 codon 47 and codon 72 polymorphism in Bangladeshi population. (2014 Oct)Mostaid MSTumour Biol
29511884Podoplanin-positive cancer-associated fibroblast recruitment within cancer stroma is associated with a higher number of single nucleotide variants in cancer cells in lung adenocarcinoma. (2018 May)Nakasone SJ Cancer Res Clin Oncol
20372852Cigarette smoking, TP53 Arg72Pro, TP53BP1 Asp353Glu and the risk of lung cancer in a Japanese population. (2010 May)Kiyohara COncol Rep
16620878Methylation and repeats in silent and nonsense mutations of p53. (2006 Jul 25)Kouidou SMutat Res
23027623MAP kinase genes and colon and rectal cancer. (2012 Dec)Slattery MLCarcinogenesis
17785079[TP53 gene polymorphisms and colorectal cancer risk in Chinese population]. (2007 Jun 5)Jia HRZhonghua Yi Xue Za Zhi
23011884Functional effect of polymorphisms in 15q25 locus on CHRNA5 mRNA, bulky DNA adducts and TP53 mutations. (2013 Apr 15)Tekpli XInt J Cancer
25126481Establishment and characterization of a singaporean chinese lung adenocarcinoma cell line with four copies of the epidermal growth factor receptor gene. (2014 Aug 1)Choong MLBiores Open Access
29486792NSAID use and somatic exomic mutations in Barrett's esophagus. (2018 Feb 27)Galipeau PCGenome Med
11857392TP53 mutation pattern of esophageal squamous cell carcinomas in a high risk area (Southern Brazil): role of life style factors. (2002 Mar 1)Putz AInt J Cancer
22217548Similar DNA methylation pattern in lung tumours from smokers and never-smokers with second-hand tobacco smoke exposure. (2012 Jul)Scesnaite AMutagenesis
20935061A novel functional DEC1 promoter polymorphism -249T>C reduces risk of squamous cell carcinoma of the head and neck. (2010 Dec)Huang YJCarcinogenesis
26200269Unique Genetic and Survival Characteristics of Invasive Mucinous Adenocarcinoma of the Lung. (2015 Aug)Shim HSJ Thorac Oncol
28415781Relevance of DNA repair gene polymorphisms to gastric cancer risk and phenotype. (2017 May 30)Carrera-Lasfuentes POncotarget
25189529Whole-genome sequencing of asian lung cancers: second-hand smoke unlikely to be responsible for higher incidence of lung cancer among Asian never-smokers. (2014 Nov 1)Krishnan VGCancer Res
29247171Computer-Aided Nodule Assessment and Risk Yield (CANARY) may facilitate non-invasive prediction of EGFR mutation status in lung adenocarcinomas. (2017 Dec 15)Clay RSci Rep
21302631Quadruple primary malignancies of liver, bladder, lung and stomach in one patient. (2010 Sep-Oct)Yhim HYTumori
15906354TP53 alterations and patterns of carcinogen exposure in a U.S. population-based study of bladder cancer. (2005 Nov 10)Kelsey KTInt J Cancer
26672058Biomolecular Markers within the Core Axis of Aging and Particulate Air Pollution Exposure in the Elderly: A Cross-Sectional Study. (2016 Jul)Pieters NEnviron Health Perspect
25882505Women who deliver twins are more likely to smoke and have high frequencies of specific SNPs: Results from a sample of African-American women who delivered preterm, low birth weight babies. (2015 Sep-Oct)Huang HAm J Hum Biol
19178978A meta-analysis of TP53 codon 72 polymorphism and lung cancer risk: evidence from 15,857 subjects. (2009 Oct)Li YLung Cancer
20728566Betel quid chewing as an environmental risk factor for breast cancer. (2010 Dec 21)Kaushal MMutat Res
26900290Genomic characterization of esophageal squamous cell carcinoma: Insights from next-generation sequencing. (2016 Feb 21)Sasaki YWorld J Gastroenterol
15055300TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer. (2004)Olivier MIARC Sci Publ
7485740TP53 mutations in upper aerodigestive squamous cell carcinomas from a group of Brazilian patients. (1995 Nov)Nagai MAAm J Surg
28145643Analysis of Fifty Hotspot Mutations of Lung Squamous Cell Carcinoma in Never-smokers. (2017 Mar)Lee HYJ Korean Med Sci
29634976High expression of synthesis of cytochrome c oxidase 2 and TP53-induced glycolysis and apoptosis regulator can predict poor prognosis in human lung adenocarcinoma. (2018 Apr 7)Liu JHum Pathol
26378065Variant Profiling of Candidate Genes in Pancreatic Ductal Adenocarcinoma. (2015 Nov)Huang JClin Chem
26601054Experience with targeted next generation sequencing for the care of lung cancer: insights into promises and limitations of genomic oncology in day-to-day practice. (2015)Rangachari DCancer Treat Commun
26175310Phylogenetic analysis of multiple FISH markers in oral tongue squamous cell carcinoma suggests that a diverse distribution of copy number changes is associated with poor prognosis. (2016 Jan 1)Wangsa DInt J Cancer
21468597TP53 codon 72 polymorphism is associated with pancreatic cancer risk in males, smokers and drinkers. (2011 May-Jun)Sonoyama TMol Med Rep
16818665TP53 and KRAS2 mutations in plasma DNA of healthy subjects and subsequent cancer occurrence: a prospective study. (2006 Jul 1)Gormally ECancer Res
19390995Small cell lung cancer: significance of RB alterations and TTF-1 expression in its carcinogenesis, phenotype, and biology. (2009 Summer)Kitamura HEndocr Pathol
9149891Cigarette smoking and chromosome 9 alterations in bladder cancer. (1997 May)Zhang ZFCancer Epidemiol Biomarkers Prev
9308707Molecular damage in the bronchial epithelium of current and former smokers. (1997 Sep 17)Wistuba IIJ Natl Cancer Inst
29141854A P53-Deficiency Gene Signature Predicts Recurrence Risk of Patients with Early-Stage Lung Adenocarcinoma. (2018 Jan)Zhao YCancer Epidemiol Biomarkers Prev
17306604Association between the TP53 codon72 polymorphism and oral cancer risk and prognosis. (2007 Nov)Kuroda YOral Oncol
25594032PICT1 expression is a poor prognostic factor in non-small cell lung cancer. (2014)Okamura KOncoscience
24942490ALK fusion and its association with other driver gene mutations in Finnish non-small cell lung cancer patients. (2014 Nov)Tuononen KGenes Chromosomes Cancer
21734801Molecular biology of pancreatic cancer. (2011 Jun 28)Zavoral MWorld J Gastroenterol
22221671Squamous cell carcinoma in Barrett's esophagus: field effect versus metastasis. (2012 Sep-Oct)Streppel MMDis Esophagus
28930282Esophageal Cancer: Genomic and Molecular Characterization, Stem Cell Compartment and Clonal Evolution. (2017 Sep 14)Testa UMedicines (Basel)
28109471Smoking status regulates a novel panel of PIWI-interacting RNAs in head and neck squamous cell carcinoma. (2017 Feb)Krishnan AROral Oncol
28210120Single nucleotide polymorphisms as susceptibility, prognostic, and therapeutic markers of nonsmall cell lung cancer. (2012)Zienolddiny SLung Cancer (Auckl)
24084248The GSTM1null (deletion) and MGMT84 rs12917 (Phe/Phe) haplotype are associated with bulky DNA adduct levels in human leukocytes. (2013 Dec 12)Molina EMutat Res
24278325Distinct effects of alcohol consumption and smoking on genetic alterations in head and neck carcinoma. (2013)Urashima MPLoS One
8118380Tobacco smoking, occupation, and p53 nuclear overexpression in early stage bladder cancer. (1994 Jan-Feb)Zhang ZFCancer Epidemiol Biomarkers Prev
24760004Frequent mutations in EGFR, KRAS and TP53 genes in human lung cancer tumors detected by ion torrent DNA sequencing. (2014)Cai XPLoS One
25249451Association of DCC, MLH1, GSTT1, GSTM1, and TP53 gene polymorphisms with colorectal cancer in Kazakhstan. (2015 Jan)Djansugurova LTumour Biol
8609061p16/CDKN2 gene and p53 gene alterations in Japanese non-smoking female lung adenocarcinoma. (1996 Feb)Takeshima YJpn J Cancer Res
15390186Benzo[a]pyrene diol epoxide-induced 9p21 aberrations associated with genetic predisposition to bladder cancer. (2004 Dec)Hazra AGenes Chromosomes Cancer
27063419Association of Single Nucleotide Polymorphisms in the Apoptosis-Related Genes TP63 and CD40 with Risk for Lung Cancer in a Chinese Han Population. (2016 Apr)Tang WTohoku J Exp Med
28975625Translational opportunities for broad-spectrum natural phytochemicals and targeted agent combinations in breast cancer. (2018 Feb 15)Dalasanur Nagaprashantha LInt J Cancer
23595658The association between TP53 Arg72Pro polymorphism and lung cancer susceptibility: evidence from 30,038 subjects. (2013 Aug)Qiao QLung
26745092Association of Histopathological Markers with Clinico- Pathological Factors in Mexican Women with Breast Cancer. (2015)Bandala CAsian Pac J Cancer Prev
19909015Combined analysis of smoking, TP53, and FGFR3 mutations in Tunisian patients with invasive and superficial high-grade bladder tumors. (2009 Dec)Ouerhani SCancer Invest
19643813Relationship between TP53 tumour suppressor gene mutations and smoking-related bulky DNA adducts in a lung cancer study population from Hungary. (2009 Nov)Anna LMutagenesis
19944185TP53 mutation profile of esophageal squamous cell carcinomas of patients from Southeastern Brazil. (2010 Feb)Rossini AMutat Res
19005564Epidemiology of doublet/multiplet mutations in lung cancers: evidence that a subset arises by chronocoordinate events. (2008)Chen ZPLoS One
22407457Development of a rapid and practical mutation screening assay for human lung adenocarcinoma. (2012 Jun)Choi HInt J Oncol
18296683Comparison of induced and cancer-associated mutational spectra using multivariate data analysis. (2008 Apr)Lewis PDCarcinogenesis
15347601Mutations in TP53, but not FGFR3, in urothelial cell carcinoma of the bladder are influenced by smoking: contribution of exogenous versus endogenous carcinogens. (2005 Jan)Wallerand HCarcinogenesis
20507599Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors. (2010 May 27)Baba YMol Cancer
25165809Effects of maternal smoking on the placental expression of genes related to angiogenesis and apoptosis during the first trimester. (2014)Kawashima APLoS One
25234657Tongue carcinoma infrequently harbor common actionable genetic alterations. (2014 Sep 19)Tan DSBMC Cancer
26164066Spectrum of gene mutations detected by next generation exome sequencing in brain metastases of lung adenocarcinoma. (2015 Sep)Preusser MEur J Cancer
26601720Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis. (2016 Feb)Bjaanaes MMMol Oncol
28256572Clinicopathological and molecular characterization of SMARCA4-deficient thoracic sarcomas with comparison to potentially related entities. (2017 Jun)Yoshida AMod Pathol
27242894TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients. (2016)Halvorsen ARFront Genet
17957785Genetic polymorphisms of MDM2, cumulative cigarette smoking and nonsmall cell lung cancer risk. (2008 Feb 15)Liu GInt J Cancer
24435975p53 signaling pathway polymorphisms associated to recurrent pregnancy loss. (2014 Mar)Fraga LRMol Biol Rep
21475450Studies on Association Between Copper Excess, Zinc Deficiency and TP53 Mutations in Esophageal Squamous Cell Carcinoma From Kashmir Valley, India-A High Risk Area. (2007 Jan)Mir MMInt J Health Sci (Qassim)
21552119Detection of high-risk HPV in head and neck squamous cell carcinomas: comparison of chromogenic in situ hybridization and a reverse line blot method. (2011 Dec)Stevens TMAppl Immunohistochem Mol Morphol
19351817Genetic mutations associated with cigarette smoking in pancreatic cancer. (2009 Apr 15)Blackford ACancer Res
25791328DNA methylation analysis of cancer-related genes in oral epithelial cells of healthy smokers. (2015 Jun)De Oliveira SRArch Oral Biol
14871814Large-scale allelotype of pancreaticobiliary carcinoma provides quantitative estimates of genome-wide allelic loss. (2004 Feb 1)Iacobuzio-Donahue CACancer Res
28346444Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility. (2017 May)Wright DJNat Genet
17059853Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms. (2007 Jan)Popanda OLung Cancer
26834999Integrated analysis of oral tongue squamous cell carcinoma identifies key variants and pathways linked to risk habits, HPV, clinical parameters and tumor recurrence. (2015)Krishnan NF1000Res
19633365Genetic classification of oral and oropharyngeal carcinomas identifies subgroups with a different prognosis. (2009)Smeets SJCell Oncol
26467027The role of human papillomavirus in head and neck squamous cell carcinoma: A case control study on a southern Chinese population. (2016 May)Chor JSJ Med Virol
15786011Frequency of loss of heterozygosity at 3 p, 9 p, 13 q, and 17 p is related to proliferative activity in smokers with stage I non-small cell lung cancer. (2005 Apr)Haga YThorac Cardiovasc Surg
18549475Genome wide SNP comparative analysis between EGFR and KRAS mutated NSCLC and characterization of two models of oncogenic cooperation in non-small cell lung carcinoma. (2008 Jun 12)Blons HBMC Med Genomics
12120703Oral lichen planus has a high rate of TP53 mutations. A study of oral mucosa in icelanD. (2002 Jun)Ogmundsdottir HMEur J Oral Sci
28169993The evolving genomic landscape of urothelial carcinoma. (2017 Feb 7)Glaser APNat Rev Urol
17693666Single-nucleotide polymorphisms at the TP53-binding or responsive promoter regions of BAX and BCL2 genes and risk of squamous cell carcinoma of the head and neck. (2007 Sep)Chen KCarcinogenesis
17575133Patterns of EGFR, HER2, TP53, and KRAS mutations of p14arf expression in non-small cell lung cancers in relation to smoking history. (2007 Jun 15)Mounawar MCancer Res
20106900International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants. (2010 Apr)Truong TCarcinogenesis
19963114Effect of combined genetic polymorphisms on lung cancer risk in northern Thai women. (2009 Dec)Klinchid JCancer Genet Cytogenet
25278450Genome-wide DNA methylation analysis of lung carcinoma reveals one neuroendocrine and four adenocarcinoma epitypes associated with patient outcome. (2014 Dec 1)Karlsson AClin Cancer Res
22975805The transcriptional landscape and mutational profile of lung adenocarcinoma. (2012 Nov)Seo JSGenome Res
21370130Single-Strand Conformation Polymorphism Analysis of Mutations in Exons 4-8 of the TP53 Gene. (2001)Vahakangas KHMethods Mol Med
24271138Association between the TP53 polymorphisms and lung cancer risk: a meta-analysis. (2014 Jan)Ye XHMol Biol Rep
27182622KRAS and TP53 mutations in bronchoscopy samples from former lung cancer patients. (2017 Feb)Gao WMol Carcinog
21790896Genetic and environmental predictors, endogenous hormones and growth factors, and risk of estrogen receptor-positive breast cancer in Japanese women. (2011 Nov)Yoshimoto NCancer Sci
25736869Molecular responses in the telomere-mitochondrial axis of ageing in the elderly: a candidate gene approach. (2015 Jan)Pieters NMech Ageing Dev
27467949PD-L1 expression in non-small cell lung cancer: Correlations with genetic alterations. (2016 May)Scheel AHOncoimmunology
16499995Increased risk of non-small cell lung cancer and frequency of somatic TP53 gene mutations in Pro72 carriers of TP53 Arg72Pro polymorphism. (2006 Apr)Szymanowska ALung Cancer
21159183p53 in head and neck cancer: functional consequences and environmental implications of TP53 mutations. (2010 Dec 15)Peltonen JKHead Neck Oncol
17980001Genetic polymorphisms associated with cigarette smoking and the risk of Graves' disease. (2008 Jun)Bufalo NEClin Endocrinol (Oxf)
22267755Prognostic value of TP53, KRAS and EGFR mutations in nonsmall cell lung cancer: the EUELC cohort. (2012 Jul)Scoccianti CEur Respir J
19096302Prognostic implication of EGFR, KRAS, and TP53 gene mutations in a large cohort of Japanese patients with surgically treated lung adenocarcinoma. (2009 Jan)Kosaka TJ Thorac Oncol
10741273The relationship between angiogenesis and the immune response in carcinogenesis and the progression of malignant disease. (2000 Jan)O'Byrne KJEur J Cancer
15574780Loss of heterozygosity of chromosome 3p21 is associated with mutant TP53 and better patient survival in non-small-cell lung cancer. (2004 Dec 1)Marsit CJCancer Res
18336951The TP53 Arg72Pro polymorphism and lung cancer risk in a population of Northern Spain. (2008 Sep)Fernandez-Rubio ALung Cancer
29335443Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing. (2018 Jan 15)Nahar RNat Commun
9816274Genetic analysis of second primary lung cancers in patients surviving small cell lung cancer. (1996 Jul)Kelley MJClin Cancer Res
29355614Head and neck squamous cell carcinoma: Genomics and emerging biomarkers for immunomodulatory cancer treatments. (2018 Jan 30)Solomon BSemin Cancer Biol
27927582Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study. (2017 Jan)Gillis NKLancet Oncol
28799801Cross-generational effects of alcohol dependence in humans on HRAS and TP53 methylation in offspring. (2017 Sep)Hill SYEpigenomics
28559012Establishment and characterization of an oral tongue squamous cell carcinoma cell line from a never-smoking patient. (2017 Jun)Wang SJOral Oncol
19950227Mutations in TP53 tumor suppressor gene in wood dust-related sinonasal cancer. (2010 Aug 1)Holmila RInt J Cancer
22154617Effect of CYP1A1 MSPI polymorphism on the relationship between TP53 mutation and CDKN2A hypermethylation in non-small cell lung cancer. (2011 Nov)Tan CArch Med Res
17258495Advances in the biology of oral cancer. (2007 Jul)Tsantoulis PKOral Oncol
15824188TP53 mutation spectrum in lung cancer is not different in women and men. (2005 Apr)Marrogi AJCancer Epidemiol Biomarkers Prev
25122428Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis. (2014 Sep)Umemura SJ Thorac Oncol
23722122Malignancy risk models for oral lesions. (2013 Sep 1)Zarate AMMed Oral Patol Oral Cir Bucal
23586029Molecular characterization of TP53 gene in human populations exposed to low-dose ionizing radiation. (2013)Brasil-Costa IBiomed Res Int
25218545Interaction between TP63 and MDM2 genes and the risk of recurrent pregnancy loss. (2014 Nov)Fraga LREur J Obstet Gynecol Reprod Biol
25355724Small-cell lung cancer detection in never-smokers: clinical characteristics and multigene mutation profiling using targeted next-generation sequencing. (2015 Jan)Sun JMAnn Oncol
22690669Differences in the quantity of DNA found in the urine and saliva of smokers versus nonsmokers: implications for the timing of epigenetic events. (2012 Jun)Simkin MEpigenomics
12619109TP53 mutations in workers exposed to occupational carcinogens. (2003 Mar)Vahakangas KHum Mutat
8692233Comparative synchronous fluorescence spectrophotometry and 32P-postlabeling analysis of PAH-DNA adducts in human lung and the relationship to TP53 mutations. (1996 Jul 5)Andreassen AMutat Res
9263533Microsatellite instability in lung cancer patients 40 years of age or younger. (1997 Jun)Sekine IJpn J Cancer Res
15371460Detection of microsatellite alterations in bronchial washings in squamous cell lung cancer: the first study from India. (2004 Aug)Malhotra PJpn J Clin Oncol
21517233TP53 - molecular soldier's mutations in bladder cancer in the Kashmiri population. (2011)Nanda MSAsian Pac J Cancer Prev
15604253Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. (2004 Dec 15)Kosaka TCancer Res
28911955Somatic Mutations and Ancestry Markers in Hispanic Lung Cancer Patients. (2017 Dec)Gimbrone NTJ Thorac Oncol
16287156Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. (2006 Jan)Zhang XHum Mutat
26873401Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population. (2016 May)Sawada GGastroenterology
27542180A Graphical Model of Smoking-Induced Global Instability in Lung Cancer. (2018 Jan-Feb)Wang YIEEE/ACM Trans Comput Biol Bioinform
17711772Significance and mechanism of microsatellite instability in laryngeal squamous cell carcinoma. (2007 Jun)Zhigang HJ Otolaryngol
25631445Comprehensive genomic characterization of head and neck squamous cell carcinomas. (2015 Jan 29)-Nature
29246019Clinicopathological and genetic characteristics of pulmonary large cell carcinoma under 2015 WHO classification: a pilot study. (2017 Nov 21)Liu ROncotarget
10489629Precancer of the human cervix. (1998)Ponten JCancer Surv
28927526Putative biomarkers for cervical cancer: SNVs, methylation and expression profiles. (2017 Jul)Cardoso MFSMutat Res
22213191DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung. (2012 Oct 1)Tekpli XInt J Cancer
28464886A lung cancer risk classifier comprising genome maintenance genes measured in normal bronchial epithelial cells. (2017 May 2)Yeo JBMC Cancer
27161973Prospective Analysis of Oncogenic Driver Mutations and Environmental Factors: Japan Molecular Epidemiology for Lung Cancer Study. (2016 Jul 1)Kawaguchi TJ Clin Oncol
27565922Hot spot mutations in Finnish non-small cell lung cancers. (2016 Sep)Maki-Nevala SLung Cancer
10863157Mutational spectra at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in T-lymphocytes of nonsmoking and smoking lung cancer patients. (2000 Jun 22)Hackman PMutat Res
17492690p53 codon 72 polymorphisms in human papillomavirus-negative and human papillomavirus-positive squamous cell carcinomas of the oropharynx. (2007 Jun 15)Perrone FCancer
7710960Family history of cancer, body weight, and p53 nuclear overexpression in Duke's C colorectal cancer. (1995 Apr)Zhang ZFBr J Cancer
19523860The role of TP53 PRO47SER and ARG72PRO single nucleotide polymorphisms in the susceptibility to bladder cancer. (2011 May-Jun)Santos LEUrol Oncol
15564288Polymorphisms in XPD and TP53 and mutation in human lung cancer. (2005 Mar)Mechanic LECarcinogenesis
26318107SASH1, a new potential link between smoking and atherosclerosis. (2015 Oct)Weidmann HAtherosclerosis
29302581Novel Genetic Associations Between Lung Cancer and Indoor Radon Exposure. (2017 Dec)Choi JRJ Cancer Prev
28968711Spectrum of germline mutations in smokers and non-smokers in Brazilian non-small-cell lung cancer (NSCLC) patients. (2017 Oct 26)Couto PPCarcinogenesis
26464434Genome-wide CpG island methylation and intergenic demethylation propensities vary among different tumor sites. (2016 Feb 18)Lee STNucleic Acids Res
26099726Fuzzy clustering demonstrates that codon 72 SNP rs1042522 of TP53 gene associated with HNSCC but not with prognoses. (2015 Dec)Pinheiro UBTumour Biol
25886176Homozygous deletions of UGT2B17 modifies effects of smoking on TP53-mutations and relapse of head and neck carcinoma. (2015 Mar 31)Mafune ABMC Cancer
27749915Human Papillomavirus 16 Infection and TP53 Mutation: Two Distinct Pathogeneses for Oropharyngeal Squamous Cell Carcinoma in an Eastern Chinese Population. (2016)Wang ZPLoS One
27286260Recurrence pattern and TP53 mutation in upper urinary tract urothelial carcinoma. (2016 Jul 19)Chen CHOncotarget
19521721Accelerated decline in lung function in cigarette smokers is associated with TP53/MDM2 polymorphisms. (2009 Oct)Hancox RJHum Genet
25911935[Genetic aspects of pancreatic cancer]. (2014)Grigor'eva INEksp Klin Gastroenterol
12619108The TP53 gene, tobacco exposure, and lung cancer. (2003 Mar)Toyooka SHum Mutat
28067794The TGF-beta/Smad4 Signaling Pathway in Pancreatic Carcinogenesis and Its Clinical Significance. (2017 Jan 5)Ahmed SJ Clin Med
19959686Assessing tumor mutations to gain insight into base excision repair sequence polymorphisms and smoking in colon cancer. (2009 Dec)Curtin KCancer Epidemiol Biomarkers Prev
28753770Molecular Characterization of Bladder Cancer in Smokers versus Nonsmokers. (2016 Jun 24)Joshi MEur Urol Focus
27352265Bladder Cancer and Genetic Mutations. (2015 Sep)Zhang XCell Biochem Biophys
12714181On the origin of G --> T transversions in lung cancer. (2003 May 15)Pfeifer GPMutat Res
18824881Synchronous and metachronous extrapancreatic malignant neoplasms in patients with intraductal papillary-mucinous neoplasm of the pancreas. (2008)Ishida MPancreatology
23794399VEGFA, FLT1, KDR and colorectal cancer: assessment of disease risk, tumor molecular phenotype, and survival. (2014 Feb)Slattery MLMol Carcinog
19623649TP53 Arg72Pro polymorphism and lung cancer risk: a meta-analysis. (2009 Dec 15)Yan LInt J Cancer
24369748TP53 genetic polymorphisms, interactions with lifestyle factors and lung cancer risk: a case control study in a Chinese population. (2013 Dec 27)Li YBMC Cancer
15572290Genotoxicity of tobacco smoke and tobacco smoke condensate: a review. (2004 Nov)DeMarini DMMutat Res
24163741Molecular biology of lung cancer. (2013 Oct)Cooper WAJ Thorac Dis
27194871Role of human papillomavirus and tumor suppressor genes in oral cancer. (2016 Jan-Apr)Manvikar VJ Oral Maxillofac Pathol
24343843Associations between cigarette smoking, hormone therapy, and folate intake with incident colorectal cancer by TP53 protein expression level in a population-based cohort of older women. (2014 Feb)Tillmans LSCancer Epidemiol Biomarkers Prev
19234440EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. (2009 Apr)Inamura KMod Pathol
26762747Clinicopathological Characteristics of RET Rearranged Lung Cancer in European Patients. (2016 Jan)Michels SJ Thorac Oncol
23723294Mutation incidence and coincidence in non small-cell lung cancer: meta-analyses by ethnicity and histology (mutMap). (2013 Sep)Dearden SAnn Oncol
20563922TP53 genetic polymorphisms and environmental risk factors associated with cervical carcinogenesis in a cohort of Brazilian women with cervical lesions. (2010)Ferreira da Silva IJ Toxicol Environ Health A
18989634Cigarette smoking, body mass index, gastro-esophageal reflux disease, and non-steroidal anti-inflammatory drug use and risk of subtypes of esophageal and gastric cancers by P53 overexpression. (2009 Apr)Figueroa JDCancer Causes Control
17624591Genetic variation of TP53, polycyclic aromatic hydrocarbon-related exposures, and breast cancer risk among women on Long Island, New York. (2008 Mar)Gaudet MMBreast Cancer Res Treat
21473292Association of TP53 intron 3, 16 bp duplication polymorphism with esophageal and gastric cancer susceptibility in Kashmir Valley. (2011)Malik MAOncol Res
27666431Clinical significance and functional validation of PPA1 in various tumors. (2016 Oct)Luo DCancer Med
29650325Improving the genetic signature of prostate cancer, the somatic mutations. (2018 Jun)Martinez-Gonzalez LJUrol Oncol
11097227Relationships of TP53 codon 72 and HRAS1 polymorphisms with lung cancer risk in an ethnically diverse population. (2000 Nov)Pierce LMCancer Epidemiol Biomarkers Prev
24761888Impact of AhR, CYP1A1 and GSTM1 genetic polymorphisms on TP53 R273G mutations in individuals exposed to polycyclic aromatic hydrocarbons. (2014)Gao MAsian Pac J Cancer Prev
14579148Inherited variants in MYH are unlikely to contribute to the risk of lung carcinoma. (2004 Jan)Al-Tassan NHum Genet
12935924The spectrum of mutations in TP53 in laryngeal cancer patients from a high-incidence population shows similarities to many of the known mutational hotspots. (2003 Sep)Barnard DCancer Genet Cytogenet
26320449MDM2 and TP53 Polymorphisms as Predictive Markers for Head and Neck Cancer in Northeast Indian Population: Effect of Gene-Gene and Gene-Environment Interactions. (2015)Bhowmik AAsian Pac J Cancer Prev
19150414Genetic predisposition and environmental risk factors to pancreatic cancer: A review of the literature. (2009 Mar-Jun)Landi SMutat Res
23857717Airway basal cells of healthy smokers express an embryonic stem cell signature relevant to lung cancer. (2013 Sep)Shaykhiev RStem Cells
28472989Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages. (2017 May 4)Yang MJ Hematol Oncol
16213358Alterations of 9p in squamous cell carcinoma and adenocarcinoma of the lung: association with smoking, TP53, and survival. (2005 Oct 15)Marsit CJCancer Genet Cytogenet
21043833Investigation on the role of p53 codon 72 polymorphism and interactions with tobacco, betel quid, and alcohol in susceptibility to cancers in a high-risk population from North East India. (2011 Mar)Ihsan RDNA Cell Biol
25280564Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma. (2014 Dec)Buas MFCarcinogenesis
22114738Hepatitis B and Hepatitis C Infection Biomarkers and TP53 Mutations in Hepatocellular Carcinomas from Colombia. (2011)Navas MCHepat Res Treat
14644339Mechanisms of esophageal cancer development in Brazilians. (2003 Nov)Ribeiro Pinto LFMutat Res
28914263Coexistent genetic alterations involving ALK, RET, ROS1 or MET in 15 cases of lung adenocarcinoma. (2018 Feb)Tang ZMod Pathol
23880854The cellular and molecular carcinogenic effects of radon exposure: a review. (2013 Jul 5)Robertson AInt J Mol Sci
18824180Fetal-juvenile origins of point mutations in the adult human tracheal-bronchial epithelium: absence of detectable effects of age, gender or smoking status. (2008 Nov 10)Sudo HMutat Res
12110621Smoking, lung cancers and their TP53 mutations. (2002 Jul)Cooper CSMutagenesis
28789369Association of TP53 codon 72 genotype polymorphism and environmental factors with esophageal squamous cell carcinoma in the Mongolian population of the Chinese region of Inner Mongolia. (2017 Aug)Li MOncol Lett
25233467Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma. (2014)Tseng TSPLoS One
29217530The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations-The Lung Cancer Mutation Consortium (LCMC2). (2018 Mar 1)Aisner DLClin Cancer Res
12401821Specific p53 immunostaining patterns are associated with smoking habits in patients with oral squamous cell carcinomas. (2002 Nov)Cruz IJ Clin Pathol