Gene: MAGED4

728239
MAGE-D4|MAGE-E1|MAGE1|MAGEE1
MAGE family member D4
protein-coding
Xp11.22
Ensembl:ENSG00000154545 MIM:300702 Vega:OTTHUMG00000042235 UniprotKB:Q96JG8
NC_000023.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MAGED4B0.521
EIF3CL0.509
F8A30.394
ERVH48-10.388
HSFX20.38
VN1R10.377
PBX2P10.377
UBN20.37
ZNF5520.369
ONECUT30.369

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
HIST1H2BB-0.213
LINC01037-0.211
HIST1H1D-0.204
ROPN1B-0.201
LRRIQ3-0.198
ITGB7-0.196
ZMYND15-0.195
APOBEC3G-0.19
HIST1H4B-0.189
FLT3LG-0.188

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of MAGED4 mRNA21298039
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of MAGED4 mRNA20660070
D004958Estradiol[Progesterone co-treated with Estradiol] results in decreased expression of MAGED4 mRNA17404688
C039671ciglitazone[ciglitazone binds to PPARG protein alternative form] which results in increased expression of MAGED4 mRNA16197558
D003976DiazinonDiazinon results in increased methylation of MAGED4 gene22964155
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of MAGED4 mRNA28412506
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of MAGED4 mRNA20660070
D011374Progesterone[Progesterone co-treated with Estradiol] results in decreased expression of MAGED4 mRNA17404688
D014635Valproic AcidValproic Acid results in increased methylation of MAGED4 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23205092The significance of MAGED4 expression in non-small cell lung cancer as analyzed by real-time fluorescence quantitative PCR. (2012 Oct)Ma QYOncol Lett