Gene: RGPD2

729857
NUP358|RANBP2L2|RGP2
RANBP2-like and GRIP domain containing 2
protein-coding
2p11.2
Ensembl:ENSG00000185304 MIM:612705 Vega:OTTHUMG00000153276 UniprotKB:P0DJD1
NC_000002.12
SNP Mapped
1   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs9636470chr2:87866942 (GRCh38.p7)T>C / T>Gnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PRSS440.492
OR7A170.478
HOXD120.477
CWH430.468
EZH20.458
OR5D140.456
C11orf530.442
OR10G20.438
ESCO20.43
OR12D10.429

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SPATA24-0.325
NOG-0.295
MMD2-0.288
HPSE2-0.286
RXRG-0.273
ZNF423-0.272
MMP11-0.271
SP8-0.268
PYGM-0.267
BHLHA15-0.266

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D001151ArsenicArsenic affects the methylation of RGPD2 gene25304211

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005096GTPase activator activityCONTRIBUTES_TOIBA21873635  
GO:0008536Ran GTPase binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0006607NLS-bearing protein import into nucleus-IBA21873635  
GO:0015031protein transport-IBA21873635  
GO:0046907intracellular transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005622intracellular-IEA-  
GO:0005634nucleus-IBA21873635  
GO:0005643nuclear pore-IBA21873635  
GO:0005737cytoplasm-IBA21873635  
GO:0005813centrosome-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal