Gene info: ID 7358

Gene: UGDH

GENE ID: 7358

Synonyms: GDH|UDP-GlcDH|UDPGDH|UGD

Description: UDP-glucose 6-dehydrogenase

Gene type: protein-coding

Location: 4p14

dbXrefs: Ensembl:ENSG00000109814 MIM:603370 Vega:OTTHUMG00000099371 UniprotKB:O60701

RefSeq: NC_000004.12

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND|AD

# Publications: 2

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 3.142e-1 (AD) 1.872e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
DNAJC3	0.827
FNDC3B	0.807
ARFGAP3	0.802
CRY1	0.799
G3BP1	0.799
NFKB1	0.793
BCL10	0.787
MPZL1	0.786
HSPD1	0.784
PDIA4	0.78

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
OR4F5	-0.465
OR4F29	-0.416
CRYBA2	-0.271
BHLHA9	-0.251
ALOX12B	-0.238
SLC7A4	-0.238
F7	-0.235
TMEM191C	-0.234
EDN3	-0.229
CYP4A11	-0.225

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00157	NADH	Small Molecule	58-68-4	Approved\|Nutraceutical	Target
DB09130	Copper	Small Molecule	7440-50-8	Approved\|Investigational	Target

ID	Drug Name	Action	PubMed
C472829	1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole	"1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased expression of UGDH mRNA"	27071940
C472829	1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole	"NFE2L2 gene mutant form inhibits the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased expression of UGDH mRNA]"	27071940
C049325	1,2-dithiol-3-thione	"1,2-dithiol-3-thione results in increased expression of UGDH mRNA"	19162173
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of UGDH mRNA"	22698814
C034086	1,5-naphthalenediamine	"1,5-naphthalenediamine affects the expression of UGDH mRNA"	17114358
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran affects the expression of UGDH mRNA"	18343893\|2070259
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of UGDH protein"	23457121
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of UGDH mRNA"	20005886\|2185183
C016403	2,4-dinitrotoluene	"2,4-dinitrotoluene affects the expression of UGDH mRNA"	21346803
C023514	2,6-dinitrotoluene	"2,6-dinitrotoluene results in decreased expression of UGDH mRNA"	20406850
C023514	2,6-dinitrotoluene	"2,6-dinitrotoluene affects the expression of UGDH mRNA"	21346803
C023035	3,4,5,3',4'-pentachlorobiphenyl	"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of UGDH protein"	23457121
C009505	4,4'-diaminodiphenylmethane	"4,4'-diaminodiphenylmethane results in decreased expression of UGDH mRNA"	18648102
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of UGDH mRNA"	27188386
C517041	(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)	"(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) results in increased expression of UGDH mRNA"	19561079
C035207	4-amino-2,6-dinitrotoluene	"4-amino-2,6-dinitrotoluene affects the expression of UGDH mRNA"	21346803
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of UGDH mRNA"	27188386
D000082	Acetaminophen	Acetaminophen results in decreased expression of UGDH mRNA	21420995\|2906747
D000082	Acetaminophen	Acetaminophen affects the expression of UGDH mRNA	17562736
D000111	Acetylcysteine	Acetylcysteine results in increased expression of UGDH mRNA	16084531
D000452	Aldrin	Aldrin results in increased expression of UGDH mRNA	18579281
C103303	alitretinoin	[pirinixic acid co-treated with alitretinoin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA	16292757
D000517	alpha-Chlorohydrin	alpha-Chlorohydrin analog results in decreased expression of UGDH protein	26597043
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of UGDH mRNA	16483693
D001151	Arsenic	[APOE protein affects the susceptibility to Arsenic] which affects the expression of UGDH mRNA	22719926
C006632	arsenic trioxide	arsenic trioxide results in decreased expression of UGDH protein	25258189
C006632	arsenic trioxide	arsenic trioxide results in increased expression of UGDH mRNA	20458559
C547126	AZM551248	AZM551248 results in increased expression of UGDH mRNA	22323515
C105430	benzofuran	benzofuran affects the expression of UGDH mRNA	17114358
D001564	Benzo(a)pyrene	Benzo(a)pyrene affects the expression of UGDH mRNA	21714911
D001564	Benzo(a)pyrene	[Soot co-treated with Benzo(a)pyrene] results in increased expression of UGDH protein modified form	24464499
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of UGDH mRNA	19770486\|2171566
D004958	Estradiol	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of UGDH mRNA	19619570
D004958	Estradiol	Estradiol results in increased expression of UGDH mRNA	19619570\|2118537
C044887	beta-methylcholine	beta-methylcholine affects the expression of UGDH mRNA	21179406
C006780	bisphenol A	bisphenol A affects the expression of UGDH mRNA	21786754
C006780	bisphenol A	bisphenol A results in decreased expression of UGDH mRNA	21269433
C006780	bisphenol A	bisphenol A results in increased expression of UGDH mRNA	28780062
C006780	bisphenol A	bisphenol A results in increased expression of UGDH mRNA	25181051
C032036	bromobenzene	bromobenzene metabolite binds to UGDH protein	17305373
C018475	butyraldehyde	butyraldehyde results in decreased expression of UGDH mRNA	26079696
D002104	Cadmium	Cadmium results in increased expression of UGDH mRNA	24067728
C037123	cadmium sulfate	[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of UGDH mRNA	18654764
D002220	Carbamazepine	Carbamazepine results in decreased expression of UGDH mRNA	17381134
D002220	Carbamazepine	Carbamazepine results in increased expression of UGDH mRNA	17381134
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of UGDH mRNA	27339419
C418118	CI 1044	CI 1044 results in increased expression of UGDH mRNA	17569694
C018021	cobaltous chloride	[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of UGDH mRNA	18654764
C018021	cobaltous chloride	cobaltous chloride results in decreased expression of UGDH mRNA	19376846
C018021	cobaltous chloride	cobaltous chloride results in increased expression of UGDH mRNA	22941251
C018021	cobaltous chloride	cobaltous chloride results in increased expression of UGDH mRNA	24386269
C018021	cobaltous chloride	cobaltous chloride results in increased expression of UGDH protein	24386269
D003300	Copper	UGDH protein binds to Copper	15359738
C030123	coumarin	coumarin results in increased expression of UGDH mRNA	18480146
D003375	Coumestrol	Coumestrol results in decreased expression of UGDH mRNA	19167446
C057862	cyanoginosin LR	cyanoginosin LR results in increased expression of UGDH mRNA	17654400
D016572	Cyclosporine	Cyclosporine results in decreased expression of UGDH mRNA	20106945
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of UGDH mRNA	21266533
D003999	Dichloroacetic Acid	Dichloroacetic Acid results in increased expression of UGDH mRNA	28962523
D002945	Cisplatin	Cisplatin results in increased expression of UGDH mRNA	19561079
D002945	Cisplatin	Cisplatin results in increased expression of UGDH protein	16803524
D004041	Dietary Fats	Dietary Fats affects the expression of UGDH mRNA	19680557
D004041	Dietary Fats	Dietary Fats results in decreased expression of UGDH mRNA	15238619\|1804283
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of UGDH mRNA	19850644
D004051	Diethylhexyl Phthalate	PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of UGDH mRNA]	19850644
D004052	Diethylnitrosamine	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of UGDH protein"	23457121
D004052	Diethylnitrosamine	"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of UGDH protein"	23457121
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of UGDH mRNA	28943392
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of UGDH mRNA	19638242
C015835	dimethyl-4-toluidine	dimethyl-4-toluidine results in increased expression of UGDH mRNA	27638505
D004147	Dioxins	Dioxins affects the expression of UGDH mRNA	20463971
D004237	Diuron	Diuron results in increased expression of UGDH mRNA	21551480
C045651	epigallocatechin gallate	epigallocatechin gallate results in increased expression of UGDH mRNA	16084531
D000431	Ethanol	Ethanol results in decreased expression of UGDH mRNA	17920746
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of UGDH mRNA	17942748
D005038	Ethylnitrosourea	Ethylnitrosourea results in increased mutagenesis of UGDH gene	15755804
C098546	ethyl tert-butyl ether	ethyl tert-butyl ether results in increased expression of UGDH protein	24090815
D005054	Eugenol	Eugenol results in increased expression of UGDH mRNA	16292757
C047360	felbamate	felbamate results in decreased expression of UGDH mRNA	17381134
C047360	felbamate	felbamate results in increased expression of UGDH mRNA	17381134
D018120	Finasteride	Finasteride results in increased expression of UGDH mRNA	24136188
D005472	Fluorouracil	UGDH protein affects the susceptibility to Fluorouracil	16217747
D005485	Flutamide	Flutamide results in increased expression of UGDH mRNA	24136188
C056933	fumonisin B1	fumonisin B1 results in increased expression of UGDH mRNA	16221962
C039281	furan	furan results in increased expression of UGDH mRNA	24183702
C039281	furan	furan results in increased expression of UGDH mRNA	26194646
C040029	gabapentin	gabapentin results in decreased expression of UGDH mRNA	17381134
C106014	gedunin	gedunin results in increased expression of UGDH mRNA	17010675
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of UGDH protein]	20884965
D019833	Genistein	Genistein results in decreased expression of UGDH protein	20884965
D019833	Genistein	Genistein results in increased expression of UGDH mRNA	15378649\|1686567
D005839	Gentamicins	Gentamicins results in increased expression of UGDH mRNA	22061828
D006118	Griseofulvin	Griseofulvin affects the expression of UGDH mRNA	12735108
D007529	Isoflavones	Isoflavones results in increased expression of UGDH mRNA	17374662
D007545	Isoproterenol	Isoproterenol results in increased expression of UGDH mRNA	21335049
D007649	Ketamine	Ketamine results in decreased expression of UGDH mRNA	20080153
C029891	lead chloride	[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of UGDH mRNA	18654764
C045463	leflunomide	leflunomide results in increased expression of UGDH mRNA	24136188
D008627	Mercuric Chloride	Mercuric Chloride affects the expression of UGDH mRNA	20353558
D008627	Mercuric Chloride	Mercuric Chloride results in increased expression of UGDH mRNA	16507785
C002950	methylformamide	methylformamide affects the expression of UGDH mRNA	17040096
C002950	methylformamide	methylformamide analog affects the expression of UGDH mRNA	17040096
D008767	Methylmercury Compounds	Methylmercury Compounds results in increased expression of UGDH mRNA	28496038
D008767	Methylmercury Compounds	Methylmercury Compounds results in increased expression of UGDH protein	28496038
D015655	1-Methyl-4-phenylpyridinium	1-Methyl-4-phenylpyridinium results in decreased expression of UGDH mRNA	24810058
C008493	methylselenic acid	methylselenic acid affects the expression of UGDH mRNA	14617803
C583365	N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of UGDH mRNA"	29244179
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in decreased expression of UGDH mRNA"	25620056
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of UGDH mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in decreased expression of UGDH mRNA"	25620056
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of UGDH mRNA"	25554681
C051752	nefazodone	nefazodone results in increased expression of UGDH mRNA	24136188
C012655	nimesulide	nimesulide results in increased expression of UGDH mRNA	24136188
C014707	nitrosobenzylmethylamine	nitrosobenzylmethylamine results in decreased expression of UGDH mRNA	17616710
C570897	NSC668394	NSC668394 results in increased expression of UGDH mRNA	27137931
C030110	oxaliplatin	[oxaliplatin co-treated with Topotecan] results in increased expression of UGDH mRNA	25729387
D000073878	Palm Oil	Palm Oil affects the expression of UGDH mRNA	19680557
D000073878	Palm Oil	Palm Oil results in decreased expression of UGDH mRNA	18042831
D052638	Particulate Matter	Particulate Matter results in increased expression of UGDH protein	17922515
D052638	Particulate Matter	Particulate Matter results in increased methylation of UGDH gene	28495853
D010416	Pentachlorophenol	Pentachlorophenol results in increased expression of UGDH mRNA	23892564
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased expression of UGDH protein	22609092
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of UGDH protein	26879310
D010629	Phenformin	Phenformin results in decreased expression of UGDH protein	4270849
D010634	Phenobarbital	Phenobarbital results in increased expression of UGDH protein	19952500
D010634	Phenobarbital	Phenobarbital affects the expression of UGDH mRNA	23091169
D010634	Phenobarbital	Phenobarbital results in increased expression of UGDH mRNA	17381134\|1916217
D010634	Phenobarbital	Phenobarbital results in increased expression of UGDH protein	24090815
D010672	Phenytoin	Phenytoin results in decreased expression of UGDH mRNA	17381134
C008922	piperine	piperine results in decreased expression of UGDH mRNA	16292757
C006253	pirinixic acid	[pirinixic acid co-treated with alitretinoin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA	16292757
C006253	pirinixic acid	pirinixic acid results in decreased expression of UGDH mRNA	18445702
C006253	pirinixic acid	pirinixic acid results in increased expression of UGDH mRNA	15375163\|1622196
D010938	Plant Oils	Plant Oils results in increased expression of UGDH mRNA	23370395
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of UGDH mRNA	19162173
C045950	propiconazole	propiconazole results in increased expression of UGDH mRNA	21278054
D011748	Pyrogallol	Pyrogallol results in increased expression of UGDH mRNA	20362636
D011794	Quercetin	Quercetin results in decreased expression of UGDH protein	18095365
D012293	Rifampin	[Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA	16292757
D012293	Rifampin	Rifampin results in increased expression of UGDH mRNA	16292757
D012715	Sesame Oil	Sesame Oil results in decreased expression of UGDH mRNA	29191790
D012822	Silicon Dioxide	Silicon Dioxide analog affects the secretion of UGDH protein	25895662
C009277	sodium arsenate	sodium arsenate results in increased expression of UGDH mRNA	16882884
C017947	sodium arsenite	sodium arsenite affects the expression of UGDH mRNA	29319823
C017947	sodium arsenite	sodium arsenite results in decreased expression of UGDH mRNA	28595984
D053260	Soot	[Soot co-treated with Benzo(a)pyrene] results in increased expression of UGDH protein modified form	24464499
D053260	Soot	Soot results in increased expression of UGDH mRNA	22461453
C013698	tallow	tallow affects the expression of UGDH mRNA	19680557
D013749	Tetrachlorodibenzodioxin	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of UGDH mRNA	19619570
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of UGDH mRNA	19619570
D013749	Tetrachlorodibenzodioxin	NFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of UGDH mRNA]	19474220
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of UGDH mRNA	18343893\|2070259
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of UGDH mRNA	16214954
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of UGDH mRNA	25975270
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of UGDH mRNA	15328365\|1580003
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of UGDH mRNA	16960034\|2055827
D013827	Thiabendazole	Thiabendazole results in increased expression of UGDH mRNA	18539377
D013853	Thioacetamide	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of UGDH mRNA	28943392
D013853	Thioacetamide	Thioacetamide results in increased expression of UGDH mRNA	23411599
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of UGDH mRNA	28065790
D014044	Tolbutamide	Tolbutamide results in decreased expression of UGDH protein	4270849
D019772	Topotecan	[oxaliplatin co-treated with Topotecan] results in increased expression of UGDH mRNA	25729387
D019772	Topotecan	Topotecan results in increased expression of UGDH mRNA	25729387
C012589	trichostatin A	trichostatin A results in increased expression of UGDH mRNA	15901671
C050414	tripterine	tripterine results in increased expression of UGDH mRNA	17010675
C057693	troglitazone	troglitazone results in increased expression of UGDH mRNA	28973697
D014415	Tunicamycin	Tunicamycin results in increased expression of UGDH mRNA	22378314
C406224	valdecoxib	valdecoxib results in increased expression of UGDH mRNA	24136188
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of UGDH mRNA"	27188386
D014635	Valproic Acid	Valproic Acid affects the expression of UGDH mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in decreased expression of UGDH mRNA	23179753\|2627250
D014635	Valproic Acid	Valproic Acid results in decreased methylation of UGDH gene	29154799
D014635	Valproic Acid	Valproic Acid results in increased expression of UGDH mRNA	17381134
D014635	Valproic Acid	Valproic Acid results in increased expression of UGDH mRNA	15901671
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of UGDH protein	17922515
D001335	Vehicle Emissions	Vehicle Emissions results in increased methylation of UGDH gene	28495853

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0003979	UDP-glucose 6-dehydrogenase activity	-	TAS	-
GO:0009055	electron transfer activity	-	TAS	9737970
GO:0051287	NAD binding	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001702	gastrulation with mouth forming second	-	IEA	-
GO:0006011	UDP-glucose metabolic process	-	TAS	9737970
GO:0006024	glycosaminoglycan biosynthetic process	-	IBA	21873635
GO:0006024	glycosaminoglycan biosynthetic process	-	TAS	9737970
GO:0006065	UDP-glucuronate biosynthetic process	-	IEA	-
GO:0006065	UDP-glucuronate biosynthetic process	-	TAS	-
GO:0022900	electron transport chain	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005634	nucleus	-	IBA	21873635
GO:0005654	nucleoplasm	-	IDA	-
GO:0005829	cytosol	-	IBA	21873635
GO:0005829	cytosol	-	TAS	-
GO:0070062	extracellular exosome	-	HDA	23533145

KEGG ID	KEGG Term
hsa00040	Pentose and glucuronate interconversions
hsa00053	Ascorbate and aldarate metabolism
hsa00500	Starch and sucrose metabolism
hsa00520	Amino sugar and nucleotide sugar metabolism
hsa01100	Metabolic pathways

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	TAS
R-HSA-156580	Phase II - Conjugation of compounds	TAS
R-HSA-156588	Glucuronidation	TAS
R-HSA-173599	Formation of the active cofactor, UDP-glucuronate	TAS
R-HSA-211859	Biological oxidations	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
20421487	Genome-wide association identifies candidate genes that influence the human electroencephalogram. (2010 May 11)	Hodgkinson CA	Proc Natl Acad Sci U S A
25829418	Proteomics Differentiate Between Thyroid-Associated Orbitopathy and Dry Eye Syndrome. (2015 Apr)	Matheis N	Invest Ophthalmol Vis Sci