Gene: UGT2B15

7366
HLUG4|UDPGT 2B8|UDPGT2B15|UDPGTH3|UGT2B8
UDP glucuronosyltransferase family 2 member B15
protein-coding
4q13.2
Ensembl:ENSG00000196620 MIM:600069 Vega:OTTHUMG00000161507 UniprotKB:P54855
NG_052676.1
PubMed
0   ANCO-SNPs
ND
4   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR6Y10.692
OR4C110.689
OR10W10.685
SLC7A130.682
OR7G20.682
OR4A150.681
OR6C760.68
OR4D60.679
OR5A10.678
GACAT10.676

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RYR3-0.299
OPHN1-0.275
SPON1-0.266
LAMA1-0.265
LRP4-0.261
PEX11A-0.259
SLC39A12-0.253
AQP4-0.252
KCNN3-0.252
CRB2-0.248

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00186LorazepamSmall Molecule846-49-1ApprovedEnzyme
DB00197TroglitazoneSmall Molecule97322-87-7Investigational|WithdrawnEnzyme
DB00295MorphineSmall Molecule57-27-2Approved|InvestigationalEnzyme
DB00313Valproic AcidSmall Molecule99-66-1Approved|InvestigationalEnzyme
DB00316AcetaminophenSmall Molecule103-90-2ApprovedEnzyme
DB00842OxazepamSmall Molecule604-75-1ApprovedEnzyme
DB00973EzetimibeSmall Molecule163222-33-1ApprovedEnzyme
DB06695Dabigatran etexilateSmall Molecule211915-06-9ApprovedEnzyme
DB11943DelafloxacinSmall Molecule189279-58-1Approved|InvestigationalEnzyme
DB13874EnasidenibSmall Molecule1446502-11-9Approved|InvestigationalEnzyme
ID Drug Name Action PubMed
C5432111,2,5,8-tetrahydroxy anthraquinone"UGT2B15 protein results in increased metabolism of 1,2,5,8-tetrahydroxy anthraquinone"7835232
C02670216-hydroxyestroneUGT2B15 protein results in increased metabolism of 16-hydroxyestrone7835232
C02670216-hydroxyestroneUGT2B15 protein results in increased metabolism of 16-hydroxyestrone7574722
C04526116-hydroxytestosteroneUGT2B15 protein results in increased metabolism of 16-hydroxytestosterone7835232
C0293501-naphtholUGT2B15 protein results in increased metabolism of 1-naphthol7835232
C0293501-naphtholUGT2B15 protein results in increased metabolism of 1-naphthol7574722
C0348892,6-dihydroxyanthraquinone"UGT2B15 protein results in increased metabolism of 2,6-dihydroxyanthraquinone"7835232
C0249802-hydroxyestroneUGT2B15 protein results in increased metabolism of 2-hydroxyestrone7835232
C0284052-naphtholUGT2B15 protein results in increased metabolism of 2-naphthol7835232
C0284052-naphtholUGT2B15 protein results in increased metabolism of 2-naphthol7574722
C0043692-phenylphenolUGT2B15 protein results in increased metabolism of 2-phenylphenol7574722
C4727913-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of UGT2B15 mRNA12958071
C0599033-hydroxybiphenylUGT2B15 protein results in increased metabolism of 3-hydroxybiphenyl7574722
C4828803-hydroxydesloratadineUGT2B15 protein results in increased glucuronidation of 3-hydroxydesloratadine15334623
C4861844,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol"4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in increased expression of UGT2B15 mRNA"16690804
C5830744,4'-hexafluorisopropylidene diphenol"UGT2B15 protein results in increased glucuronidation of and results in decreased activity of 4,4'-hexafluorisopropylidene diphenol"24349450
C0319614-benzylphenolUGT2B15 protein results in increased metabolism of 4-benzylphenol7835232
C0319614-benzylphenolUGT2B15 protein results in increased metabolism of 4-benzylphenol7574722
C0140364-hydroxyestradiolUGT2B15 protein results in increased metabolism of 4-hydroxyestradiol7835232
C0264184-hydroxyestroneUGT2B15 protein results in increased metabolism of 4-hydroxyestrone7835232
C0248364-nitrophenolUGT2B15 protein results in increased metabolism of 4-nitrophenol7835232
C0248364-nitrophenolUGT2B15 protein results in increased metabolism of 4-nitrophenol7574722
C0190464-phenylphenolUGT2B15 protein results in increased glucuronidation of 4-phenylphenol28500425|8399210
C0190464-phenylphenolUGT2B15 protein results in increased metabolism of 4-phenylphenol7835232
C0190464-phenylphenolUGT2B15 protein results in increased metabolism of 4-phenylphenol7574722
C1052604-tert-octylphenolUGT2B15 protein results in increased glucuronidation of 4-tert-octylphenol28500425
C0305905-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronideUGT2B15 protein results in increased abundance of 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide7835232
C0712876-hydroxyquinolineUGT2B15 protein results in increased metabolism of 6-hydroxyquinoline7835232
C0842367-hydroxy-4-trifluoromethylcoumarinsilybin inhibits the reaction [UGT2B15 protein results in increased glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin]15155549
C0842367-hydroxy-4-trifluoromethylcoumarinUGT2B15 protein results in increased glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin15155549
C0314777-hydroxycoumarinUGT2B15 protein results in increased metabolism of 7-hydroxycoumarin7835232
C0314777-hydroxycoumarinUGT2B15 protein results in increased metabolism of 7-hydroxycoumarin7574722
C0399287-hydroxycoumarin glucuronideUGT2B15 protein results in increased abundance of 7-hydroxycoumarin glucuronide7835232
C0399287-hydroxycoumarin glucuronideUGT2B15 protein results in increased abundance of 7-hydroxycoumarin glucuronide7574722
C4298457-hydroxyflavoneUGT2B15 protein results in increased metabolism of 7-hydroxyflavone7835232
C0561478-hydroxyquinoline glucuronideUGT2B15 protein results in increased abundance of 8-hydroxyquinoline glucuronide7835232
C0561478-hydroxyquinoline glucuronideUGT2B15 protein results in increased abundance of 8-hydroxyquinoline glucuronide7574722
D000082AcetaminophenAcetaminophen results in decreased expression of UGT2B15 mRNA21420995|2906747
D000082AcetaminophenAcetaminophen results in decreased expression of UGT2B15 protein29067470
D020106AcrylamideAcrylamide results in decreased expression of UGT2B15 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of UGT2B15 gene27153756
D000393Air PollutantsAir Pollutants analog results in decreased expression of UGT2B15 mRNA21757418
C010078alizarinUGT2B15 protein results in increased metabolism of alizarin7835232
C010078alizarinUGT2B15 protein results in increased metabolism of alizarin7574722
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of UGT2B15 mRNA16690804
D013196DihydrotestosteroneEstradiol promotes the reaction [UGT2B15 protein results in increased glucuronidation of Dihydrotestosterone]16690804
D013196Dihydrotestosteronefulvestrant inhibits the reaction [Dihydrotestosterone results in increased expression of UGT2B15 mRNA]16690804
D013196DihydrotestosteroneUGT2B15 protein results in increased glucuronidation of Dihydrotestosterone16690804|8399210
C016775alpha-terpineolUGT2B15 protein results in increased metabolism of alpha-terpineol7574722
D000654AmobarbitalUGT2B15 protein results in increased glycosylation of Amobarbital15013842
C028895androstane-3,17-diol glucuronide"UGT2B15 protein results in increased abundance of androstane-3,17-diol glucuronide"7835232
C028895androstane-3,17-diol glucuronide"UGT2B15 protein SNP results in increased abundance of androstane-3,17-diol glucuronide"12386133
D015113Androstane-3,17-diol"UGT2B15 protein results in increased glucuronidation of Androstane-3,17-diol"8399210
D015113Androstane-3,17-diol"UGT2B15 protein results in increased metabolism of Androstane-3,17-diol"7835232
D015113Androstane-3,17-diol"UGT2B15 protein SNP results in increased metabolism of Androstane-3,17-diol"12386133
D000732AndrostanolsUGT2B15 protein results in increased glucuronidation of Androstanols12756209
D047310ApigeninUGT2B15 protein results in increased metabolism of Apigenin7835232
D047310ApigeninUGT2B15 protein results in increased metabolism of Apigenin7574722
C000228aristolochic acid Iaristolochic acid I results in increased expression of UGT2B15 mRNA17483316
D001205Ascorbic Acid[Quercetin co-treated with Ascorbic Acid] results in decreased expression of UGT2B15 mRNA17639512
C006680baicaleinUGT2B15 protein results in increased metabolism of baicalein7835232
D019324beta-Naphthoflavonebeta-Naphthoflavone results in decreased expression of UGT2B15 mRNA22258563
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of UGT2B15 mRNA22258563
D004958Estradiol[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of UGT2B15 mRNA20823114
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of UGT2B15 mRNA19619570
D004958EstradiolEstradiol promotes the reaction [UGT2B15 protein results in increased glucuronidation of Dihydrotestosterone]16690804
D004958EstradiolEstradiol results in increased expression of and results in increased activity of UGT2B15 protein16690804
D004958EstradiolEstradiol results in increased expression of UGT2B15 mRNA16690804|1961957
D004958Estradiolfulvestrant inhibits the reaction [Estradiol results in increased expression of UGT2B15 mRNA]16690804
D001663BilirubinBilirubin results in decreased activity of UGT2B15 protein15334623
C006780bisphenol Abisphenol A results in increased expression of UGT2B15 mRNA23524099
C006780bisphenol AUGT2B15 protein affects the metabolism of and affects the activity of bisphenol A24980262
C006780bisphenol AUGT2B15 protein alternative form results in increased glucuronidation of bisphenol A21404072
C006780bisphenol AUGT2B15 protein results in increased glucuronidation of bisphenol A18990428|2140407
C006780bisphenol Abisphenol A results in decreased expression of UGT2B15 mRNA25181051
C006780bisphenol AUGT2B15 gene polymorphism affects the metabolism of bisphenol A23404680
C038091butylparabenbutylparaben results in increased expression of UGT2B15 mRNA23524099
C018475butyraldehydebutyraldehyde results in decreased expression of UGT2B15 mRNA26079696
C028031cadmium acetatecadmium acetate affects the expression of UGT2B15 mRNA16249259
D002220CarbamazepineCarbamazepine results in increased expression of UGT2B15 mRNA17112801
C073316carvacrolUGT2B15 protein results in increased metabolism of carvacrol7835232
C075856carveolUGT2B15 protein results in increased metabolism of carveol7574722
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of UGT2B15 mRNA17851650
C043561chrysinUGT2B15 protein results in increased metabolism of chrysin7835232
C007078citronellolUGT2B15 protein results in increased metabolism of citronellol7574722
D003300CopperCopper results in decreased expression of UGT2B15 mRNA22465980
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of UGT2B15 mRNA19167446
D003513CycloheximideCycloheximide results in increased expression of UGT2B15 mRNA16690804
D016572CyclosporineCyclosporine results in decreased expression of UGT2B15 mRNA27989131
D003907DexamethasoneDexamethasone results in increased expression of UGT2B15 mRNA21146967
D003994Bucladesine[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of UGT2B15 mRNA20823114
D004008DiclofenacDiclofenac results in decreased activity of UGT2B15 protein15334623
D004008DiclofenacUGT2B15 protein results in increased glucuronidation of Diclofenac15843492
D004028DienestrolUGT2B15 protein results in increased metabolism of Dienestrol7835232
D002117CalcitriolCalcitriol results in decreased expression of UGT2B15 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in decreased expression of UGT2B15 mRNA21592394
C070609EMD 53998EMD 53998 analog results in increased expression of UGT2B15 mRNA24977338
D004642EmodinUGT2B15 protein results in increased metabolism of Emodin7835232
D004642EmodinUGT2B15 protein results in increased metabolism of Emodin7574722
D060754EquolEquol results in increased expression of UGT2B15 mRNA16865672
C007628esculetinUGT2B15 protein results in increased metabolism of esculetin7835232
C007628esculetinUGT2B15 protein results in increased metabolism of esculetin7574722
D004964EstriolUGT2B15 protein results in increased glucuronidation of Estriol2116769
D004964EstriolUGT2B15 protein results in increased metabolism of Estriol7835232
C032095estriol glucuronideUGT2B15 protein results in increased abundance of estriol glucuronide7835232
D005054EugenolUGT2B15 protein results in increased metabolism of Eugenol7835232
D005054EugenolUGT2B15 protein SNP results in increased metabolism of Eugenol12386133
D005054EugenolUGT2B15 protein results in increased metabolism of Eugenol7574722
D000069438EzetimibeUGT2B15 protein results in increased glucuronidation of Ezetimibe14977865
C082360fipronilfipronil results in increased expression of UGT2B15 mRNA23962444
D005445FlunitrazepamFlunitrazepam results in decreased activity of UGT2B15 protein15334623
D019793FluoresceinUGT2B15 protein results in increased metabolism of Fluorescein7835232
C041357fluorescein glucuronideUGT2B15 protein results in increased abundance of fluorescein glucuronide7835232
D005557FormaldehydeFormaldehyde results in increased expression of UGT2B15 mRNA23649840
C070081fulvestrantfulvestrant inhibits the reaction [Dihydrotestosterone results in increased expression of UGT2B15 mRNA]16690804
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol results in increased expression of UGT2B15 mRNA]16690804
C037032galanginUGT2B15 protein results in increased metabolism of galangin7835232
D019833GenisteinGenistein results in increased expression of UGT2B15 mRNA16690804|1686567
C107601glabridinUGT2B15 protein results in increased glucuronidation of glabridin25765239
C001337hexafluoroisopropanolUGT2B15 protein results in increased metabolism of hexafluoroisopropanol7574722
C079687hexafluoroisopropanol glucuronideUGT2B15 protein results in increased abundance of hexafluoroisopropanol glucuronide7574722
C001419hydroxyphenytoinUGT2B15 protein results in increased metabolism of hydroxyphenytoin7835232
D006923HymecromoneHymecromone results in increased activity of UGT2B15 protein26875642
D006923Hymecromonelicochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT2B15 protein]26875642
D006923HymecromoneUGT2B15 protein results in increased metabolism of Hymecromone7835232
D006923HymecromoneUGT2B15 protein SNP results in increased metabolism of Hymecromone12386133
D006923HymecromoneUGT2B15 protein results in increased metabolism of Hymecromone7574722
D006923HymecromoneUGT2B15 protein results in increased glucuronidation of Hymecromone16023900
D007052IbuprofenUGT2B15 protein results in increased glucuronidation of Ibuprofen15843492
D007501IronIron deficiency results in decreased expression of UGT2B15 mRNA16629162
C022871isoborneolUGT2B15 protein results in increased metabolism of isoborneol7574722
C021829isoborneol glucuronideUGT2B15 protein results in increased abundance of isoborneol glucuronide7574722
C561808isomentholUGT2B15 protein results in increased metabolism of isomenthol7574722
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of UGT2B15 mRNA26752646
C070840licochalcone Alicochalcone A inhibits the reaction [Hymecromone results in increased activity of UGT2B15 protein]26875642
C018584linaloolUGT2B15 protein results in increased metabolism of linalool7574722
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of NR1H4 protein] which results in increased expression of UGT2B15 mRNA21311750
C506658lorcaserinUGT2B15 protein results in increased carbamoylation of and results in increased glucuronidation of lorcaserin22259019
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of UGT2B15 mRNA20823114
D008610MentholUGT2B15 protein results in increased metabolism of Menthol7574722
C044963menthol glucuronideUGT2B15 protein results in increased abundance of menthol glucuronide7574722
D008731MethoxychlorUGT2B15 protein results in increased glucuronidation of Methoxychlor metabolite15205390
C005273naringeninUGT2B15 protein results in increased metabolism of naringenin7835232
C005273naringeninUGT2B15 protein SNP results in increased metabolism of naringenin12386133
C005273naringeninUGT2B15 protein results in increased metabolism of naringenin7574722
C464660obeticholic acidobeticholic acid results in increased expression of UGT2B15 mRNA27939613
D010076OxazepamUGT2B15 protein results in increased metabolism of Oxazepam12386133
D010076OxazepamUGT2B15 protein SNP results in increased metabolism of Oxazepam12386133
C026256oxazepam glucuronideUGT2B15 protein results in increased abundance of oxazepam glucuronide12386133
C026256oxazepam glucuronideUGT2B15 protein SNP results in increased abundance of oxazepam glucuronide12386133
D010634PhenobarbitalPhenobarbital results in increased expression of UGT2B15 mRNA8399210
D010634PhenobarbitalPhenobarbital affects the expression of UGT2B15 mRNA19159669
D010634PhenobarbitalPhenobarbital results in decreased expression of UGT2B15 mRNA19084549
D010634PhenobarbitalPhenobarbital results in increased expression of UGT2B15 mRNA22258563
D010634PhenobarbitalPhenobarbital results in increased expression of UGT2B15 mRNA7574722
D020113PhenolphthaleinUGT2B15 protein results in increased glucuronidation of Phenolphthalein8399210
D020113PhenolphthaleinUGT2B15 protein results in increased glucuronidation of Phenolphthalein analog8399210
D020113PhenolphthaleinUGT2B15 protein results in increased metabolism of Phenolphthalein7835232
C016651phenolphthalein glucuronideUGT2B15 protein results in increased abundance of phenolphthalein glucuronide7835232
D010637PhenolsulfonphthaleinUGT2B15 protein results in increased glucuronidation of Phenolsulfonphthalein8399210
C049288p-nitrophenol glucuronideUGT2B15 protein results in increased abundance of p-nitrophenol glucuronide7835232
C049288p-nitrophenol glucuronideUGT2B15 protein results in increased abundance of p-nitrophenol glucuronide7574722
D011794Quercetin[Quercetin co-treated with Ascorbic Acid] results in decreased expression of UGT2B15 mRNA17639512
D011794QuercetinUGT2B15 protein results in increased metabolism of Quercetin7835232
D015125OxyquinolineUGT2B15 protein results in increased metabolism of Oxyquinoline7835232
D015125OxyquinolineUGT2B15 protein results in increased metabolism of Oxyquinoline7574722
C115070ranirestatUGT2B15 protein results in increased glycosylation of ranirestat15013842
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of UGT2B15 mRNA19167446
C534628SCH 23390UGT2B15 protein results in increased metabolism of SCH 233907835232
D012603ScopoletinUGT2B15 protein results in increased metabolism of Scopoletin7835232
D012603ScopoletinUGT2B15 protein results in increased metabolism of Scopoletin7574722
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of UGT2B15 mRNA25895662
C440975silybinsilybin inhibits the reaction [UGT2B15 protein results in increased glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin]15155549
C034019terpinenol-4UGT2B15 protein results in increased metabolism of terpinenol-47574722
D013739Testosterone[Testosterone co-treated with Calcitriol] results in decreased expression of UGT2B15 mRNA21592394
D013739TestosteroneTestosterone results in decreased expression of UGT2B15 mRNA21592394
D013739TestosteroneUGT2B15 protein results in increased metabolism of Testosterone7835232
C015529testosterone glucuronateUGT2B15 protein results in increased abundance of testosterone glucuronate7835232
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of UGT2B15 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of UGT2B15 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of UGT2B15 mRNA21296121
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of UGT2B15 mRNA21215274|2172422
D013806TheophyllineTheophylline results in decreased expression of UGT2B15 mRNA16083514
D014635Valproic AcidValproic Acid results in decreased expression of UGT2B15 mRNA29154799
D014635Valproic AcidValproic Acid results in decreased methylation of UGT2B15 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0001972retinoic acid bindingNOTIDA20308471  
GO:0008194UDP-glycosyltransferase activity-IBA21873635  
GO:0015020glucuronosyltransferase activity-IDA20056724  22579593  
GO ID GO Term Qualifier Evidence PubMed
GO:0006805xenobiotic metabolic process-TAS7835232  
GO:0008202steroid metabolic process-TAS7835232  
GO:0052695cellular glucuronidation-IDA20056724  22579593  
GO ID GO Term Qualifier Evidence PubMed
GO:0005789endoplasmic reticulum membrane-IEA-  
GO:0016021integral component of membrane-IEA-  
GO:0031090organelle membrane-IEA-  
GO:0043231intracellular membrane-bounded organelle-IBA21873635  
KEGG ID KEGG Term
hsa00040Pentose and glucuronate interconversions
hsa00053Ascorbate and aldarate metabolism
hsa00140Steroid hormone biosynthesis
hsa00500Starch and sucrose metabolism
hsa00514Other types of O-glycan biosynthesis
hsa00830Retinol metabolism
hsa00860Porphyrin and chlorophyll metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00982Drug metabolism - cytochrome P450
hsa00983Drug metabolism - other enzymes
hsa01100Metabolic pathways
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-156580Phase II - Conjugation of compoundsTAS
R-HSA-156588GlucuronidationTAS
R-HSA-211859Biological oxidationsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23197595Steroidogenic enzyme expression in the human fetal liver and potential role in the endocrinology of pregnancy. (2013 Mar)O'Shaughnessy PJMol Hum Reprod
19821798Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system. (2010 Feb)Court MHDrug Metab Rev
12167564N-glucuronidation of nicotine and cotinine in human: formation of cotinine glucuronide in liver microsomes and lack of catalysis by 10 examined UDP-glucuronosyltransferases. (2002 Sep)Ghosheh ODrug Metab Dispos
24408517Simultaneous quantification of the abundance of several cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase enzymes in human liver microsomes using multiplexed targeted proteomics. (2014 Apr)Achour BDrug Metab Dispos