Gene: VDR

7421
NR1I1|PPP1R163
vitamin D receptor
protein-coding
12q13.11
Ensembl:ENSG00000111424 MIM:601769 Vega:OTTHUMG00000169890 UniprotKB:P11473
NG_008731.1
PubMed
ND|AD
84   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.729e-1 (AD)  5.954e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CDCP10.77
SLA0.73
MSR10.722
SIGLEC90.708
STK100.707
C5AR10.706
SLC16A30.706
RBM470.702
NAMPT0.697
PIM10.695

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SNX22-0.398
OLIG1-0.343
NEU4-0.341
KCNJ10-0.327
HES5-0.324
ARSF-0.32
GPR17-0.309
NPFFR1-0.308
HHATL-0.306
MMD2-0.298

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00136CalcitriolSmall Molecule32222-06-3Approved|NutraceuticalTarget
DB00146CalcidiolSmall Molecule19356-17-3Approved|NutraceuticalTarget
DB00153ErgocalciferolSmall Molecule50-14-6Approved|NutraceuticalTarget
DB00169CholecalciferolSmall Molecule67-97-0Approved|NutraceuticalTarget
DB00910ParicalcitolSmall Molecule131918-61-1Approved|InvestigationalTarget
DB01070DihydrotachysterolSmall Molecule67-96-9ApprovedTarget
DB01436AlfacalcidolSmall Molecule41294-56-8Approved|NutraceuticalTarget
DB02300CalcipotriolSmall Molecule112965-21-6ApprovedTarget
DB034511-alpha, 25-dihydroxyl-20-epi-22-oxa-24, 26 ,27-trihomovitamin D3Small MoleculeExperimentalTarget
DB04258SeocalcitolSmall Molecule134404-52-7Experimental|InvestigationalTarget
DB04540CholesterolSmall Molecule57-88-5Approved|Experimental|InvestigationalTarget
DB04796InecalcitolSmall Molecule163217-09-2Experimental|InvestigationalTarget
DB04891BecocalcidiolSmall Molecule524067-21-8InvestigationalTarget
DB05024CTA018Small Molecule-InvestigationalTarget
DB05295EldecalcitolSmall Molecule104121-92-8InvestigationalTarget
DB06194ElocalcitolSmall Molecule199798-84-0InvestigationalTarget
DB06410DoxercalciferolSmall Molecule54573-75-0ApprovedTarget
DB07530(1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diolSmall MoleculeExperimentalTarget
DB087421,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z)Small MoleculeExperimentalTarget
DB11094Vitamin DSmall Molecule1406-16-2Approved|NutraceuticalTarget
DB11672CurcuminSmall Molecule458-37-7Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0137211,24,25-trihydroxyvitamin D3"1,24,25-trihydroxyvitamin D3 affects the reaction [Calcitriol binds to VDR protein]"7530193
C0630871,24-dihydroxyvitamin D2"1,24-dihydroxyvitamin D2 binds to VDR protein"10927029
C0876301,25-dihydroxy-16-ene-vitamin D3"1,25-dihydroxy-16-ene-vitamin D3 affects the reaction [Calcitriol binds to VDR protein]"7530193
C0461271,25-dihydroxy-26,27-dimethylcholecalciferol"1,25-dihydroxy-26,27-dimethylcholecalciferol binds to and results in increased activity of VDR protein"20153625
C0461271,25-dihydroxy-26,27-dimethylcholecalciferol"[1,25-dihydroxy-26,27-dimethylcholecalciferol binds to and results in increased activity of VDR protein] which results in increased expression of CDKN1A mRNA"20153625
C0461271,25-dihydroxy-26,27-dimethylcholecalciferol"[1,25-dihydroxy-26,27-dimethylcholecalciferol binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA"20153625
C0461271,25-dihydroxy-26,27-dimethylcholecalciferol"[1,25-dihydroxy-26,27-dimethylcholecalciferol binds to and results in increased activity of VDR protein] which results in increased expression of CYP3A4 mRNA"20153625
C0461271,25-dihydroxy-26,27-dimethylcholecalciferol"[1,25-dihydroxy-26,27-dimethylcholecalciferol binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA"20153625
C0461271,25-dihydroxy-26,27-dimethylcholecalciferol"Curcumin inhibits the reaction [1,25-dihydroxy-26,27-dimethylcholecalciferol binds to VDR protein]"20153625
C0461271,25-dihydroxy-26,27-dimethylcholecalciferol"Lithocholic Acid inhibits the reaction [1,25-dihydroxy-26,27-dimethylcholecalciferol binds to VDR protein]"20153625
C0035641,25-dihydroxyergocalciferol"1,25-dihydroxyergocalciferol results in increased expression of and affects the localization of VDR protein"22751936
C0979491,25-dihydroxyvitamin D"1,25-dihydroxyvitamin D binds to VDR protein"15837528
C0979491,25-dihydroxyvitamin D"[1,25-dihydroxyvitamin D co-treated with Okadaic Acid] promotes the reaction [VDR protein mutant form binds to MED1 protein]"16059639
C0979491,25-dihydroxyvitamin D"[1,25-dihydroxyvitamin D co-treated with Okadaic Acid] results in increased activity of VDR protein mutant form"16059639
C0979491,25-dihydroxyvitamin D"[1,25-dihydroxyvitamin D co-treated with U 0126] results in increased expression of VDR protein"15331595
C0979491,25-dihydroxyvitamin D"1,25-dihydroxyvitamin D inhibits the reaction [VDR protein binds to CDC25A enhancer]"23112173
C0979491,25-dihydroxyvitamin D"1,25-dihydroxyvitamin D promotes the reaction [MXD1 protein binds to VDR protein]"23112173
C0979491,25-dihydroxyvitamin D"1,25-dihydroxyvitamin D promotes the reaction [MYC protein binds to VDR protein]"23112173
C0979491,25-dihydroxyvitamin D"1,25-dihydroxyvitamin D promotes the reaction [VDR protein binds to RXRA protein]"15837528
C0979491,25-dihydroxyvitamin D"1,25-dihydroxyvitamin D results in increased stability of and results in increased expression of VDR protein"15331595
C0979491,25-dihydroxyvitamin D"2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [HRAS protein inhibits the reaction [1,25-dihydroxyvitamin D results in increased activity of VDR protein]]"18829283
C0979491,25-dihydroxyvitamin D"HRAS protein inhibits the reaction [1,25-dihydroxyvitamin D results in increased activity of VDR protein]"18829283
C0979491,25-dihydroxyvitamin D"VDR protein affects the reaction [1,25-dihydroxyvitamin D results in increased degradation of and results in decreased expression of MYC protein]"23112173
C0979491,25-dihydroxyvitamin D"1,25-dihydroxyvitamin D results in increased activity of VDR protein"18829283
C0979491,25-dihydroxyvitamin D"1,25-dihydroxyvitamin D results in increased expression of VDR protein"11751517
C0979491,25-dihydroxyvitamin D"bisindolylmaleimide I inhibits the reaction [1,25-dihydroxyvitamin D results in increased activity of VDR protein]"18829283
C0979491,25-dihydroxyvitamin D"Dexamethasone promotes the reaction [1,25-dihydroxyvitamin D results in increased expression of VDR protein]"11751517
C0979491,25-dihydroxyvitamin D"Go 6976 inhibits the reaction [1,25-dihydroxyvitamin D results in increased activity of VDR protein]"18829283
C4080471,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3"1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3 promotes the reaction [VDR protein mutant form binds to MED1 protein]"16059639
C4080471,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3"1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3 promotes the reaction [VDR protein mutant form binds to NCOA2 protein]"16059639
C4080471,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3"1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3 results in increased activity of VDR protein mutant form"16059639
C0388061,4-dihydropyridine"1,4-dihydropyridine results in increased activity of VDR protein"25257666
C0238501 alpha,24-dihydroxyvitamin D3"1 alpha,24-dihydroxyvitamin D3 binds to VDR protein"10927029
C0238501 alpha,24-dihydroxyvitamin D3"VDR gene polymorphism affects the susceptibility to 1 alpha,24-dihydroxyvitamin D3"15734288
C0425331 alpha-hydroxyergocalciferol1 alpha-hydroxyergocalciferol results in increased activity of VDR protein17997857
C0425331 alpha-hydroxyergocalciferol1 alpha-hydroxyergocalciferol results in increased activity of VDR protein17997857
C0425331 alpha-hydroxyergocalciferol1 alpha-hydroxyergocalciferol results in increased activity of VDR protein17997857
C1039581-hydroxyvitamin D51-hydroxyvitamin D5 results in increased expression of VDR protein16051482
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of VDR mRNA19933214
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased expression of VDR mRNA]15930183
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased expression of VDR protein]15930183
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein]15879110
C53359924a-homo-1,15-dihydroxyergocalciferol"24a-homo-1,15-dihydroxyergocalciferol results in increased expression of and affects the localization of VDR protein"22751936
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one"2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [HRAS protein inhibits the reaction [1,25-dihydroxyvitamin D results in increased activity of VDR protein]]"18829283
C10445025-hydroxyvitamin DVDR gene SNP affects the abundance of 25-hydroxyvitamin D20363324
C04048826,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3"26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to MED1 protein]"16059639
C04048826,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3"26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to NCOA2 protein]"16059639
C04048826,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3"26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog results in increased activity of VDR protein mutant form"16059639
C5211672-methylene-19-nor-(20S)-1 alpha-hydroxy-bishomopregnacalciferol2-methylene-19-nor-(20S)-1 alpha-hydroxy-bishomopregnacalciferol binds to VDR protein17444814
C4558603-ketolithocholic acid3-ketolithocholic acid results in increased activity of VDR protein21291553
C4558603-ketolithocholic acid3-ketolithocholic acid binds to and results in increased activity of VDR protein15489543
C4558603-ketolithocholic acid3-ketolithocholic acid results in increased activity of VDR protein21291553
C4558603-ketolithocholic acid3-ketolithocholic acid results in increased activity of VDR protein mutant form21291553
C4558603-ketolithocholic acid3-ketolithocholic acid results in increased activity of VDR protein21291553
C4558603-ketolithocholic acid3-ketolithocholic acid results in increased activity of VDR protein mutant form21291553
C4558603-ketolithocholic acid3-ketolithocholic acid results in increased activity of VDR protein21291553
C0017463-methoxytyramineCalcitriol promotes the reaction [VDR protein results in increased abundance of 3-methoxytyramine]27450565
C0017463-methoxytyramineVDR protein results in increased abundance of 3-methoxytyramine27450565
C0462303-oxocholan-24-oic acid3-oxocholan-24-oic acid results in increased activity of VDR protein15708356
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VDR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VDR mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of VDR mRNA29067470
C016601afimoxifeneafimoxifene results in decreased expression of VDR protein8593782
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of VDR mRNA25483621
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of VDR protein25483621
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of VDR mRNA22100608
D016604Aflatoxin B1VDR polymorphism affects the susceptibility to Aflatoxin B125483621
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of VDR mRNA23630614
C412373AG 1879AG 1879 inhibits the reaction [Estradiol results in increased expression of VDR protein]15930183
D000447AldehydesAldehydes results in increased expression of VDR mRNA25014914
D019386AlendronateVDR gene polymorphism affects the susceptibility to Alendronate12608943|1573903
D019386Alendronate"VDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate]"15739035
D019386AlendronateVDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Raloxifene Hydrochloride]15739035
C008088alfacalcidolalfacalcidol binds to [VDR protein binds to RXRA protein]20947021
C008088alfacalcidolalfacalcidol binds to VDR protein modified form20947021
C008088alfacalcidolalfacalcidol promotes the reaction [[VDR protein binds to RXRA protein] which binds to MED1 protein modified form]20947021
C008088alfacalcidolalfacalcidol promotes the reaction [[VDR protein binds to RXRA protein] which binds to NCOA1 protein modified form]20947021
C008088alfacalcidolalfacalcidol results in increased activity of VDR protein17997857
C008088alfacalcidolalfacalcidol results in increased activity of VDR protein17997857|1958139
C008088alfacalcidol[alfacalcidol results in increased activity of VDR protein] which results in increased metabolism of Bile Acids and Salts19581390
C008088alfacalcidolalfacalcidol results in increased activity of VDR protein17997857
C103303alitretinoinalitretinoin affects the activity of VDR protein16936639
C103303alitretinoin[alitretinoin co-treated with Calcitriol] results in increased stability of [RXRA protein binds to VDR protein]16204233
C103303alitretinoinalitretinoin promotes the reaction [VDR protein binds to BGLAP gene]12898515
C103303alitretinoinalitretinoin results in increased degradation of VDR protein12898515
D017962alpha-Linolenic Acidalpha-Linolenic Acid results in increased expression of VDR mRNA19667161
D017962alpha-Linolenic Acid[Calcitriol co-treated with alpha-Linolenic Acid] results in increased expression of VDR mRNA19667161
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]]19244278
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of VDR mRNA21298039
D000643Ammonium ChlorideAmmonium Chloride affects the expression of VDR mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of VDR mRNA24449571
C015001arsenitearsenite results in decreased expression of VDR protein15037631
D001241AspirinVDR polymorphism affects the susceptibility to Aspirin15066917
D001280AtrazineAtrazine results in decreased expression of VDR mRNA25929836
D001554BenzeneBenzene results in increased expression of VDR mRNA12928149
D001564Benzo(a)pyrenealpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]]19244278
D001564Benzo(a)pyreneBenzo(a)pyrene affects the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP1A1 promoter]]22837390
D001564Benzo(a)pyreneBenzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]19244278
D001564Benzo(a)pyrene[Calcitriol co-treated with Benzo(a)pyrene] results in increased expression of VDR protein22837390
D001564Benzo(a)pyreneVDR mutant form inhibits the reaction [Calcitriol promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]22837390
D001564Benzo(a)pyreneBenzo(a)pyrene promotes the reaction [AHR protein binds to VDR promoter]19654925
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of VDR mRNA22228805
D004958Estradiol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased expression of VDR mRNA]15930183
D004958Estradiol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased expression of VDR protein]15930183
D004958EstradiolAG 1879 inhibits the reaction [Estradiol results in increased expression of VDR protein]15930183
D004958EstradiolEstradiol promotes the reaction [JUN protein binds to VDR promoter]17088408
D004958EstradiolEstradiol promotes the reaction [SP1 protein binds to VDR promoter]17088408
D004958EstradiolEstradiol results in increased expression of VDR mRNA15930183|1708840
D004958EstradiolEstradiol results in increased expression of VDR protein15930183
D004958Estradiolfulvestrant inhibits the reaction [Estradiol results in increased expression of VDR protein]17088408
D004958Estradiolmethyl-beta-cyclodextrin inhibits the reaction [Estradiol results in increased expression of VDR protein]15930183
D004958Estradiolpyrazolanthrone inhibits the reaction [Estradiol results in increased expression of VDR protein]15930183
D004958EstradiolSuramin inhibits the reaction [Estradiol results in increased expression of VDR protein]15930183
D004958EstradiolU 0126 inhibits the reaction [Estradiol results in increased expression of VDR protein]17088408
D004958EstradiolEstradiol results in increased expression of VDR protein1315250
D004958EstradiolTamoxifen inhibits the reaction [Estradiol results in increased expression of VDR protein]1315250
D001629Bezafibrate[Calcitriol co-treated with Bezafibrate] results in increased expression of VDR mRNA19667161
D001647Bile Acids and Salts[alfacalcidol results in increased activity of VDR protein] which results in increased metabolism of Bile Acids and Salts19581390
D001647Bile Acids and SaltsVDR protein results in increased metabolism of Bile Acids and Salts15725701
C034786bis(4-hydroxycinnamoyl)methane[bis(4-hydroxycinnamoyl)methane analog co-treated with APP protein] results in increased expression of VDR mRNA22029407
C070515bisindolylmaleimide I"bisindolylmaleimide I inhibits the reaction [1,25-dihydroxyvitamin D results in increased activity of VDR protein]"18829283
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Calcitriol results in increased expression of VDR mRNA]20006981
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Chenodeoxycholic Acid results in increased expression of VDR mRNA]20006981
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA]20006981
C006780bisphenol Abisphenol A results in decreased expression of VDR mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of VDR gene28505145
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of VDR mRNA22079614
C018475butyraldehydebutyraldehyde results in increased expression of VDR mRNA26079696
C487049BXL628BXL628 binds to and affects the activity of VDR protein15572423
D002101Cacodylic AcidCacodylic Acid results in decreased expression of VDR mRNA16122865
D019256Cadmium ChlorideCadmium Chloride promotes the reaction [VDR protein binds to NCOA2 protein]21229763
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of VDR mRNA25596134
D019256Cadmium ChlorideCadmium Chloride results in increased expression of VDR mRNA23741332
C055085calcipotrienecalcipotriene affects the reaction [Calcitriol binds to VDR protein]7530193
C055085calcipotrieneVDR promoter SNP affects the susceptibility to calcipotriene15864137
D002118CalciumVDR gene polymorphism affects the metabolism of Calcium15883634|1604825
D002118CalciumVDR gene polymorphism affects the susceptibility to Calcium15861036
D002118CalciumVDR protein affects the abundance of Calcium11500311
D002118CalciumCalcium affects the expression of VDR mRNA15913539
D002136Calcium, Dietary"Calcium, Dietary affects the expression of VDR mRNA"15905206
C505748CD4528CD4528 binds to and results in increased activity of VDR protein15860548
C505748CD4528CD4528 promotes the reaction [VDR protein binds to RXRA protein]15860548
C505748CD4528CD4528 binds to and results in increased activity of VDR protein15860548
D002512Cephalothin[Cephalothin co-treated with Neomycin] results in increased expression of VDR mRNA24657338
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in increased expression of VDR mRNA20006981
D002635Chenodeoxycholic Acidbisindolylmaleimide I inhibits the reaction [Chenodeoxycholic Acid results in increased expression of VDR mRNA]20006981
D002635Chenodeoxycholic AcidChenodeoxycholic Acid promotes the reaction [Calcitriol results in increased expression of VDR mRNA]20006981
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in increased expression of VDR mRNA20006981
C004656chloroacetaldehydechloroacetaldehyde results in decreased expression of VDR mRNA25596134
C007036cholanic acidcholanic acid binds to and results in increased activity of VDR protein21291553
C007036cholanic acidcholanic acid binds to and results in increased activity of VDR protein mutant form21291553
C007036cholanic acidcholanic acid binds to and results in increased activity of VDR protein21291553
C007036cholanic acidcholanic acid binds to and results in increased activity of VDR protein mutant form21291553
D002784CholesterolCholesterol metabolite binds to VDR protein16051528
D002784CholesterolVDR gene SNP affects the abundance of Cholesterol25498546
D019826Cholic AcidCholic Acid results in increased localization of VDR protein20371703
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of VDR mRNA28472532
D002922CiguatoxinsCiguatoxins affects the expression of VDR mRNA18353800
D019327Copper SulfateCopper Sulfate results in decreased expression of VDR mRNA19549813
D003474CurcuminCurcumin binds to and results in increased activity of VDR protein20153625
D003474Curcumin[Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CDKN1A mRNA20153625
D003474Curcumin[Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA20153625
D003474Curcumin[Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CYP3A4 mRNA20153625
D003474Curcumin[Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA20153625
D003474Curcumin"Curcumin inhibits the reaction [1,25-dihydroxy-26,27-dimethylcholecalciferol binds to VDR protein]"20153625
D003474CurcuminCurcumin promotes the reaction [VDR protein binds to NCOA1 protein]20153625
D003474CurcuminCurcumin promotes the reaction [VDR protein binds to RXRA protein]20153625
D003520CyclophosphamideCyclophosphamide results in increased expression of VDR mRNA27281708
D016572CyclosporineCyclosporine results in decreased expression of VDR mRNA25596134
D003561CytarabineVDR gene polymorphism affects the susceptibility to Cytarabine15713801
D003630DaunorubicinDaunorubicin results in decreased activity of VDR protein25257666
D003630DaunorubicinVDR gene polymorphism affects the susceptibility to Daunorubicin15713801
C014347decitabine[decitabine co-treated with trichostatin A] results in increased expression of VDR mRNA17891453
C014347decitabine[decitabine co-treated with trichostatin A] results in increased expression of VDR protein17891453
D003676DeferoxamineDeferoxamine results in increased expression of VDR mRNA20368581
D015255IdarubicinIdarubicin results in decreased activity of VDR protein25257666
D003907DexamethasoneDexamethasone results in increased expression of VDR mRNA20006981
D003907Dexamethasone"Dexamethasone promotes the reaction [1,25-dihydroxyvitamin D results in increased expression of VDR protein]"11751517
D003907DexamethasoneDexamethasone results in increased expression of VDR mRNA10694374|2273378
D003907DexamethasoneDexamethasone results in decreased expression of VDR mRNA20006981
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of VDR mRNA21266533
D002945CisplatinCisplatin results in increased expression of VDR mRNA27594783
C000944dicrotophosdicrotophos results in increased expression of VDR mRNA28302478
D019259Lamivudine[Zidovudine co-treated with Lamivudine] results in decreased expression of VDR mRNA11741158
D004052DiethylnitrosamineCholecalciferol inhibits the reaction [[Hexachlorobenzene co-treated with Diethylnitrosamine] results in increased expression of VDR protein]28634113
D004052Diethylnitrosamine[Hexachlorobenzene co-treated with Diethylnitrosamine] results in decreased expression of VDR protein28634113
D002117CalcitriolCalcitriol results in increased activity of VDR protein alternative form15992766
D002117CalcitriolCalcitriol binds to and results in increased expression of VDR protein18410235
D002117CalcitriolCalcitriol analog binds to and affects the folding of and results in decreased degradation of VDR protein15857747
D002117CalcitriolCalcitriol analog binds to and results in increased activity of VDR protein15857747
D002117CalcitriolCalcitriol results in increased activity of VDR protein21291553
D002117Calcitriol"1,24,25-trihydroxyvitamin D3 affects the reaction [Calcitriol binds to VDR protein]"7530193
D002117Calcitriol[alitretinoin co-treated with Calcitriol] results in increased stability of [RXRA protein binds to VDR protein]16204233
D002117Calcitriolalpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]]19244278
D002117CalcitriolBenzo(a)pyrene affects the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP1A1 promoter]]22837390
D002117CalcitriolBenzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]19244278
D002117Calcitriolcalcipotriene affects the reaction [Calcitriol binds to VDR protein]7530193
D002117CalcitriolCalcitriol analog binds to and results in increased activity of VDR protein10799658
D002117CalcitriolCalcitriol binds to and affects the activity of VDR protein15572423|1607635
D002117CalcitriolCalcitriol binds to and results in increased activity of and results in increased localization of VDR protein20371703
D002117CalcitriolCalcitriol binds to and results in increased activity of VDR protein15489543|1557859
D002117CalcitriolCalcitriol binds to and results in increased activity of VDR protein mutant form15489543|2129155
D002117Calcitriol[Calcitriol binds to and results in increased activity of VDR protein] promotes the reaction [VDR protein binds to CYP7A1 promoter]19106115
D002117Calcitriol[Calcitriol binds to and results in increased activity of VDR protein] promotes the reaction [VDR protein binds to PPARGC1A protein]19106115
D002117Calcitriol[Calcitriol binds to and results in increased activity of VDR protein] results in decreased activity of [HNF4A protein co-treated with PPARGC1A protein]19106115
D002117Calcitriol[Calcitriol binds to and results in increased activity of VDR protein] which results in decreased expression of CYP7A1 mRNA19106115
D002117Calcitriol[Calcitriol binds to and results in increased activity of VDR protein] which results in increased expression of CDH1 mRNA15489543
D002117Calcitriol[Calcitriol binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA15489543|1818026
D002117Calcitriol[Calcitriol binds to and results in increased activity of VDR protein] which results in increased expression of CYP3A4 mRNA15489543|1557859
D002117Calcitriol[Calcitriol binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA15489543|1818026
D002117CalcitriolCalcitriol binds to VDR protein10875257|1092702
D002117CalcitriolCalcitriol binds to VDR protein mutant form14525957
D002117Calcitriol[Calcitriol binds to VDR protein] promotes the reaction [VDR protein binds to RXRA protein]21917910
D002117Calcitriol[Calcitriol binds to VDR protein] which binds to HOXA10 promoter16632680
D002117Calcitriol[Calcitriol binds to VDR protein] which results in decreased activity of CTNNB1 mRNA20043299
D002117Calcitriol[Calcitriol binds to VDR protein] which results in increased expression of HOXA10 mRNA16632680
D002117Calcitriol[Calcitriol co-treated with alpha-Linolenic Acid] results in increased expression of VDR mRNA19667161
D002117Calcitriol[Calcitriol co-treated with Benzo(a)pyrene] results in increased expression of VDR protein22837390
D002117Calcitriol[Calcitriol co-treated with Bezafibrate] results in increased expression of VDR mRNA19667161
D002117Calcitriol[Calcitriol co-treated with Docosahexaenoic Acids] results in increased expression of VDR mRNA19667161
D002117Calcitriol[Calcitriol co-treated with GW 501516] results in increased expression of VDR mRNA19667161
D002117Calcitriol[Calcitriol co-treated with pirinixic acid] results in increased expression of VDR mRNA19667161
D002117Calcitriol[Calcitriol co-treated with resveratrol] results in increased expression of VDR mRNA16267019
D002117Calcitriol[Calcitriol co-treated with VDR protein] results in decreased expression of MAOA mRNA27450565
D002117Calcitriol[Calcitriol co-treated with VDR protein] results in increased expression of CDH2 protein26210580
D002117Calcitriol[Calcitriol co-treated with VDR protein] results in increased expression of COMT mRNA27450565
D002117Calcitriol[Calcitriol co-treated with VDR protein] results in increased expression of CYP24A1 mRNA21115105
D002117Calcitriol[Calcitriol co-treated with VDR protein] results in increased expression of TH mRNA26210580
D002117Calcitriol[Calcitriol co-treated with VDR protein] results in increased expression of TH protein26210580
D002117CalcitriolCalcitriol inhibits the reaction [VDR protein binds to NCOR1 protein]22466564
D002117CalcitriolCalcitriol inhibits the reaction [VDR protein binds to NCOR2 protein]21917910|2246656
D002117CalcitriolCalcitriol inhibits the reaction [VDR protein binds to VDR protein]21917910
D002117CalcitriolCalcitriol inhibits the reaction [VDR protein results in increased expression of SLC18A2 mRNA]27450565
D002117CalcitriolCalcitriol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]24792400
D002117CalcitriolCalcitriol promotes the reaction [CTNNB1 protein binds to VDR protein]16051482
D002117CalcitriolCalcitriol promotes the reaction [MAPK1 protein results in increased phosphorylation of VDR protein]20371703
D002117CalcitriolCalcitriol promotes the reaction [MAPK3 protein results in increased phosphorylation of VDR protein]20371703
D002117CalcitriolCalcitriol promotes the reaction [NCOA1 protein binds to VDR protein]25279795
D002117CalcitriolCalcitriol promotes the reaction [NCOA2 protein binds to VDR protein]25279795
D002117CalcitriolCalcitriol promotes the reaction [RXRA protein binds to and results in increased activity of VDR protein]25279795
D002117CalcitriolCalcitriol promotes the reaction [salvin results in increased expression of VDR protein]11504768
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to BGLAP enhancer]17293108
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to CAMP promoter]15985530
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to COMT promoter]27450565
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to CYP1A1 promoter]22837390
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to CYP24A1 mRNA]20371703
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]15919092|1924427
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to CYP7A1 mRNA]20371703
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to HNF4A protein]20371703
D002117CalcitriolCalcitriol promotes the reaction [[VDR protein binds to MED1 protein] which binds to CYP24A1 promoter]15919092
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to NCOA1 protein]15489543|1557859
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to NCOA2 protein]15578590
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to NCOA3 protein]15578590
D002117CalcitriolCalcitriol promotes the reaction [[VDR protein binds to NCOA3 protein] which binds to CYP24A1 promoter]15919092
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to PPARGC1A protein]20371703
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to RUNX2 enhancer]17293108
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to RXRA protein]15578590|2015362
D002117CalcitriolCalcitriol promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP24A1 promoter]15919092
D002117CalcitriolCalcitriol promotes the reaction [[VDR protein binds to RXRA protein] which binds to SLC30A10 promoter]27107558
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to TRPV6 enhancer]17293108
D002117CalcitriolCalcitriol promotes the reaction [VDR protein results in decreased expression of DRD2 mRNA]27450565
D002117CalcitriolCalcitriol promotes the reaction [VDR protein results in increased abundance of 3-methoxytyramine]27450565
D002117CalcitriolCalcitriol promotes the reaction [VDR protein results in increased abundance of Homovanillic Acid]27450565
D002117CalcitriolCalcitriol results in decreased degradation of and affects the localization of VDR protein24792400
D002117CalcitriolCalcitriol results in decreased expression of VDR mRNA16002434
D002117CalcitriolCalcitriol results in increased activity of VDR protein16280049|1636587
D002117CalcitriolCalcitriol results in increased activity of VDR protein alternative form15992766
D002117CalcitriolCalcitriol results in increased activity of [VDR protein co-treated with RXRA protein]19106115|2037170
D002117Calcitriol[Calcitriol results in increased activity of [VDR protein co-treated with RXRA protein]] inhibits the reaction [PPARGC1A protein results in increased expression of CYP7A1 mRNA]20371703
D002117Calcitriol[Calcitriol results in increased activity of [VDR protein co-treated with RXRA protein]] which results in decreased expression of CYP7A1 mRNA19106115|2037170
D002117Calcitriol[Calcitriol results in increased activity of [VDR protein co-treated with RXRA protein]] which results in increased expression of CYP24A1 mRNA20371703
D002117CalcitriolCalcitriol results in increased activity of VDR protein mutant form22466564
D002117Calcitriol[Calcitriol results in increased activity of VDR protein] which results in increased expression of SLC30A10 mRNA27107558
D002117CalcitriolCalcitriol results in increased expression of and affects the localization of VDR protein22751936
D002117CalcitriolCalcitriol results in increased expression of VDR mRNA11158396|1566445
D002117CalcitriolCalcitriol results in increased expression of VDR protein11158396|1587642
D002117CalcitriolCalcitriol results in increased localization of VDR protein16204233
D002117CalcitriolCalcitriol results in increased localization of [VDR protein co-treated with CAV1 protein]20371703
D002117CalcitriolCalcitriol results in increased localization of [VDR protein co-treated with CSK protein]20371703
D002117CalcitriolCalcitriol results in increased phosphorylation of VDR protein20371703
D002117Calcitriol[[Etoposide results in increased expression of TP73 protein] which results in increased expression of VDR protein] which results in increased susceptibility to Calcitriol17716971
D002117CalcitriolGenistein promotes the reaction [Calcitriol results in increased expression of VDR mRNA]15955619
D002117CalcitriolGenistein promotes the reaction [Calcitriol results in increased expression of VDR protein]15955619
D002117CalcitriolHR protein inhibits the reaction [Calcitriol results in increased activity of VDR protein]22466564
D002117CalcitriolHR protein inhibits the reaction [Calcitriol results in increased activity of VDR protein mutant form]22466564
D002117CalcitriolLipopolysaccharides inhibits the reaction [Calcitriol results in increased expression of VDR protein]15876428
D002117CalcitriolMAPK1 protein promotes the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]20371703
D002117CalcitriolMAPK3 protein promotes the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]20371703
D002117Calcitriolmaxacalcitol affects the reaction [Calcitriol binds to VDR protein]7530193
D002117CalcitriolNCOA1 protein promotes the reaction [Calcitriol promotes the reaction [RXRA protein binds to and results in increased activity of VDR protein]]25279795
D002117CalcitriolNCOA1 protein promotes the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]20371703
D002117CalcitriolNCOA2 protein promotes the reaction [Calcitriol promotes the reaction [RXRA protein results in increased activity of VDR protein]]25279795
D002117CalcitriolNCOA3 protein promotes the reaction [Calcitriol promotes the reaction [RXRA protein results in increased activity of VDR protein]]25279795
D002117CalcitriolNCOR1 protein inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]20371703
D002117CalcitriolNCOR1 protein inhibits the reaction [[Calcitriol results in increased activity of [VDR protein co-treated with RXRA protein]] which results in increased expression of CYP24A1 mRNA]20371703
D002117CalcitriolNCOR1 protein promotes the reaction [[Calcitriol results in increased activity of [VDR protein co-treated with RXRA protein]] inhibits the reaction [PPARGC1A protein results in increased expression of CYP7A1 mRNA]]20371703
D002117CalcitriolNCOR2 protein inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]20371703
D002117CalcitriolNCOR2 protein inhibits the reaction [[Calcitriol results in increased activity of [VDR protein co-treated with RXRA protein]] which results in increased expression of CYP24A1 mRNA]20371703
D002117CalcitriolNCOR2 protein promotes the reaction [[Calcitriol results in increased activity of [VDR protein co-treated with RXRA protein]] inhibits the reaction [PPARGC1A protein results in increased expression of CYP7A1 mRNA]]20371703
D002117CalcitriolPPARGC1A protein promotes the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]20371703
D002117CalcitriolPPARGC1A protein promotes the reaction [[Calcitriol results in increased activity of [VDR protein co-treated with RXRA protein]] which results in increased expression of CYP24A1 mRNA]20371703
D002117CalcitriolRELA protein promotes the reaction [Calcitriol results in increased activity of VDR protein]20206692
D002117CalcitriolRXRA protein promotes the reaction [Calcitriol promotes the reaction [NCOA1 protein binds to VDR protein]]25279795
D002117CalcitriolRXRA protein promotes the reaction [Calcitriol promotes the reaction [NCOA2 protein binds to VDR protein]]25279795
D002117Calcitriolsaracatinib inhibits the reaction [Calcitriol results in increased phosphorylation of VDR protein]20371703
D002117Calcitriolseocalcitol inhibits the reaction [Calcitriol binds to VDR protein]7530193
D002117Calcitrioltrichostatin A inhibits the reaction [HR protein inhibits the reaction [Calcitriol results in increased activity of VDR protein]]22466564
D002117CalcitriolU 0126 inhibits the reaction [Calcitriol promotes the reaction [MAPK1 protein results in increased phosphorylation of VDR protein]]20371703
D002117CalcitriolU 0126 inhibits the reaction [Calcitriol promotes the reaction [MAPK3 protein results in increased phosphorylation of VDR protein]]20371703
D002117CalcitriolU 0126 inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 mRNA]]20371703
D002117CalcitriolU 0126 inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP7A1 mRNA]]20371703
D002117CalcitriolU 0126 inhibits the reaction [MAPK1 protein promotes the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]]20371703
D002117CalcitriolU 0126 inhibits the reaction [MAPK3 protein promotes the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]]20371703
D002117CalcitriolValproic Acid promotes the reaction [[Calcitriol co-treated with VDR protein] results in increased expression of CYP24A1 mRNA]21115105
D002117CalcitriolVDR gene polymorphism affects the susceptibility to Calcitriol15861036
D002117CalcitriolVDR mutant form inhibits the reaction [Calcitriol promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]22837390
D002117CalcitriolVDR mutant form inhibits the reaction [Calcitriol results in decreased expression of PTHLH mRNA]21664243
D002117CalcitriolVDR protein affects the reaction [Calcitriol results in increased expression of CYP3A4 mRNA]21742782
D002117CalcitriolVDR protein promotes the reaction [Calcitriol results in increased expression of ABCB1 mRNA]19460946
D002117CalcitriolZK159222 inhibits the reaction [Calcitriol results in increased expression of VDR mRNA]15922086
D002117CalcitriolZK159222 inhibits the reaction [Calcitriol results in increased expression of VDR protein]15922086
D002117CalcitriolCalcitriol binds to and affects the activity of VDR protein25855982
D002117CalcitriolCalcitriol affects the localization of VDR protein15647825
D002117CalcitriolCalcitriol binds to and results in increased activity of VDR protein mutant form21291553
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]15647825
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to LRP5 enhancer]17293108
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to SPP1 promoter]15647825
D002117CalcitriolCalcitriol results in decreased degradation of VDR protein16467308
D002117CalcitriolCalcitriol results in increased activity of VDR protein17997857|2129155
D002117CalcitriolCalcitriol results in increased expression of and results in decreased degradation of VDR protein16467308
D002117CalcitriolCalcitriol results in increased expression of VDR mRNA17035339
D002117CalcitriolCalcitriol results in increased expression of VDR protein16368784|1795914
D002117CalcitriolMED1 protein promotes the reaction [Calcitriol results in increased activity of VDR protein]16324150
D002117Calcitriol"pregna-4,17-diene-3,16-dione promotes the reaction [Calcitriol results in increased expression of VDR protein]"17959142
D002117CalcitriolVDR results in increased susceptibility to Calcitriol17035339
D002117CalcitriolCalcitriol binds to and results in increased activity of VDR protein25279795
D002117CalcitriolCalcitriol binds to and affects the activity of VDR protein25855982
D002117CalcitriolCalcitriol binds to and affects the activity of VDR protein25855982
D002117Calcitriol"1,25-dihydroxy-16-ene-vitamin D3 affects the reaction [Calcitriol binds to VDR protein]"7530193
D002117Calcitriolbisindolylmaleimide I inhibits the reaction [Calcitriol results in increased expression of VDR mRNA]20006981
D002117CalcitriolCalcitriol analog binds to VDR protein17110116
D002117CalcitriolCalcitriol binds to VDR protein17110116|1744481
D002117CalcitriolCalcitriol inhibits the reaction [[Lipopolysaccharides co-treated with Glucose] results in decreased expression of VDR mRNA]21788014
D002117CalcitriolCalcitriol inhibits the reaction [[Lipopolysaccharides co-treated with Glucose] results in decreased expression of VDR protein]21788014
D002117CalcitriolCalcitriol results in increased expression of VDR15746989
D002117CalcitriolCalcitriol results in increased expression of VDR mRNA20006981|2178801
D002117CalcitriolCalcitriol results in increased expression of VDR protein21788014|9525346
D002117CalcitriolChenodeoxycholic Acid promotes the reaction [Calcitriol results in increased expression of VDR mRNA]20006981
D002117CalcitriolCalcitriol results in decreased expression of VDR mRNA17535883
D002117CalcitriolCalcitriol binds to and results in increased activity of VDR protein mutant form21291553
D002117CalcitriolCalcitriol results in increased activity of VDR protein17997857|2129155
D002117CalcitriolCalcitriol affects the activity of VDR protein16046118
D002117CalcitriolCalcitriol analog binds to VDR protein8533897
D002117CalcitriolCalcitriol binds to and results in increased activity of VDR protein15798098|1590536
D002117CalcitriolCalcitriol binds to VDR protein10470102|1282971
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to PPARGC1A protein]15908514
D002117CalcitriolCalcitriol promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP24A1 promoter]15992766
D002117CalcitriolCalcitriol promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP3A4 promoter]15992766
D01565024,25-Dihydroxyvitamin D 3"24,25-Dihydroxyvitamin D 3 results in increased activity of VDR protein"17997857
D01565024,25-Dihydroxyvitamin D 3"24,25-Dihydroxyvitamin D 3 results in increased activity of VDR protein"17997857
D01565024,25-Dihydroxyvitamin D 3"24,25-Dihydroxyvitamin D 3 results in increased activity of VDR protein"17997857
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 binds to [VDR protein binds to RXRA protein]20947021
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 binds to VDR protein modified form20947021
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 promotes the reaction [[VDR protein binds to RXRA protein] which binds to MED1 protein modified form]20947021
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 promotes the reaction [[VDR protein binds to RXRA protein] which binds to NCOA1 protein modified form]20947021
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 promotes the reaction [[VDR protein binds to RXRA protein] which binds to NCOA2 protein modified form]20947021
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 promotes the reaction [[VDR protein binds to RXRA protein] which binds to NCOA3 protein modified form]20947021
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 promotes the reaction [[VDR protein binds to RXRA protein] which binds to NR0B1 protein modified form]20947021
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 promotes the reaction [[VDR protein binds to RXRA protein] which binds to NR0B2 protein modified form]20947021
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 promotes the reaction [[VDR protein binds to RXRA protein] which binds to NRIP1 protein modified form]20947021
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 promotes the reaction [[VDR protein binds to RXRA protein] which binds to PPARGC1A protein modified form]20947021
C118756dihydroxy-vitamin D3dihydroxy-vitamin D3 promotes the reaction [[VDR protein binds to RXRA protein] which binds to PPARGC1B protein modified form]20947021
D011397PromegestonePromegestone results in increased expression of VDR protein7662588
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of VDR mRNA17374397
D004281Docosahexaenoic Acids[Calcitriol co-treated with Docosahexaenoic Acids] results in increased expression of VDR mRNA19667161
D004281Docosahexaenoic AcidsDocosahexaenoic Acids results in increased expression of VDR mRNA19667161
D004298DopamineVDR protein results in increased abundance of Dopamine27450565
D004317DoxorubicinDoxorubicin results in decreased activity of VDR protein25257666
D004317DoxorubicinDoxorubicin results in increased expression of VDR mRNA17716971
C547512eldecalcitoleldecalcitol binds to VDR protein26038696
C547512eldecalcitoleldecalcitol binds to [VDR protein binds to RXRA protein]20947021
C547512eldecalcitoleldecalcitol binds to VDR protein modified form20947021
C547512eldecalcitoleldecalcitol metabolite binds to VDR protein26038696
C547512eldecalcitoleldecalcitol promotes the reaction [[VDR protein binds to RXRA protein] which binds to MED1 protein modified form]20947021
C547512eldecalcitoleldecalcitol promotes the reaction [[VDR protein binds to RXRA protein] which binds to NCOA1 protein modified form]20947021
C547512eldecalcitoleldecalcitol promotes the reaction [[VDR protein binds to RXRA protein] which binds to NCOA2 protein modified form]20947021
C547512eldecalcitoleldecalcitol promotes the reaction [[VDR protein binds to RXRA protein] which binds to NCOA3 protein modified form]20947021
C547512eldecalcitoleldecalcitol promotes the reaction [[VDR protein binds to RXRA protein] which binds to NR0B1 protein modified form]20947021
C547512eldecalcitoleldecalcitol promotes the reaction [[VDR protein binds to RXRA protein] which binds to NR0B2 protein modified form]20947021
C547512eldecalcitoleldecalcitol promotes the reaction [[VDR protein binds to RXRA protein] which binds to NRIP1 protein modified form]20947021
C547512eldecalcitoleldecalcitol promotes the reaction [[VDR protein binds to RXRA protein] which binds to PPARGC1A protein modified form]20947021
C547512eldecalcitoleldecalcitol promotes the reaction [[VDR protein binds to RXRA protein] which binds to PPARGC1B protein modified form]20947021
D004726Endosulfan[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of VDR mRNA26159488
C118739entinostatentinostat results in increased expression of VDR mRNA27188386
D004964EstriolEstriol results in increased expression of VDR mRNA14992164|1577541
D004967EstrogensESR1 protein affects the reaction [Estrogens results in increased expression of VDR mRNA]15664452
D004967EstrogensESR2 protein affects the reaction [Estrogens results in increased expression of VDR mRNA]15664452
D004966Estrogens, Conjugated (USP)"VDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate]"15739035
D004966Estrogens, Conjugated (USP)"VDR gene polymorphism affects the susceptibility to [Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate]"15739035
D004997Ethinyl EstradiolVDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of ALPL protein]12521655
D004997Ethinyl EstradiolVDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of BGLAP protein]12521655
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of VDR mRNA20186393
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of VDR protein20186393
D005047Etoposide[[Etoposide results in increased expression of TP73 protein] which results in increased expression of VDR protein] which results in increased susceptibility to Calcitriol17716971
D005047EtoposideEtoposide results in increased expression of VDR mRNA17716971
D005047EtoposideTP73 protein affects the reaction [Etoposide results in increased expression of VDR mRNA]17716971
D005047EtoposideVDR gene polymorphism affects the susceptibility to Etoposide15713801
D005047EtoposideVDR intron polymorphism affects the susceptibility to Etoposide12969965
D005054EugenolEugenol results in increased expression of VDR mRNA17374397
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol results in increased expression of VDR protein]17088408
C070081fulvestrantfulvestrant inhibits the reaction [Genistein results in increased expression of VDR protein]17088408
C070081fulvestrantfulvestrant inhibits the reaction [glycitein results in increased expression of VDR protein]17088408
C070081fulvestrantfulvestrant results in decreased expression of VDR protein15930183
D019833Genisteinfulvestrant inhibits the reaction [Genistein results in increased expression of VDR protein]17088408
D019833GenisteinGenistein promotes the reaction [Calcitriol results in increased expression of VDR mRNA]15955619
D019833GenisteinGenistein promotes the reaction [Calcitriol results in increased expression of VDR protein]15955619
D019833GenisteinGenistein promotes the reaction [SP1 protein binds to VDR promoter]17088408
D019833GenisteinGenistein results in increased expression of VDR mRNA12710998|1708840
D019833GenisteinGenistein results in increased expression of VDR protein12710998|1708840
D019833GenisteinTamoxifen inhibits the reaction [Genistein results in increased expression of VDR mRNA]12710998
D019833GenisteinU 0126 inhibits the reaction [Genistein results in increased expression of VDR protein]17088408
D005947GlucoseCalcitriol inhibits the reaction [[Lipopolysaccharides co-treated with Glucose] results in decreased expression of VDR mRNA]21788014
D005947GlucoseCalcitriol inhibits the reaction [[Lipopolysaccharides co-treated with Glucose] results in decreased expression of VDR protein]21788014
D005947Glucose[Lipopolysaccharides co-treated with Glucose] results in decreased expression of VDR mRNA21788014
D005947Glucose[Lipopolysaccharides co-treated with Glucose] results in decreased expression of VDR protein21788014
C086566glyciteinfulvestrant inhibits the reaction [glycitein results in increased expression of VDR protein]17088408
C086566glyciteinglycitein promotes the reaction [SP1 protein binds to VDR promoter]17088408
C086566glyciteinglycitein results in increased expression of VDR mRNA17088408
C086566glyciteinglycitein results in increased expression of VDR protein17088408
C086566glyciteinU 0126 inhibits the reaction [glycitein results in increased expression of VDR protein]17088408
C081021Go 6976Go 6976 inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein]15879110
C081021Go 6976"Go 6976 inhibits the reaction [1,25-dihydroxyvitamin D results in increased activity of VDR protein]"18829283
C425931GW 501516[Calcitriol co-treated with GW 501516] results in increased expression of VDR mRNA19667161
C425931GW 501516GW 501516 results in increased expression of VDR mRNA19667161
D006581HexachlorobenzeneCholecalciferol inhibits the reaction [[Hexachlorobenzene co-treated with Diethylnitrosamine] results in increased expression of VDR protein]28634113
D006581Hexachlorobenzene[Hexachlorobenzene co-treated with Diethylnitrosamine] results in decreased expression of VDR protein28634113
D006719Homovanillic AcidCalcitriol promotes the reaction [VDR protein results in increased abundance of Homovanillic Acid]27450565
D006719Homovanillic AcidVDR protein results in increased abundance of Homovanillic Acid27450565
D017313FenretinideCholecalciferol promotes the reaction [Fenretinide results in increased expression of VDR]17024972
D017313FenretinideFenretinide results in increased expression of VDR17024972
D017313FenretinideFenretinide results in increased expression of VDR mRNA28973697
D002112CalcifediolCalcifediol results in increased activity of VDR protein21291553
D002112CalcifediolCalcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]24792400
D002112CalcifediolCalcifediol results in decreased degradation of and affects the localization of VDR protein24792400
D002112CalcifediolCalcifediol results in increased activity of VDR protein17997857
D002112CalcifediolCalcifediol results in increased activity of VDR protein mutant form21291553
D002112CalcifediolKetoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]]24792400
D002112CalcifediolVDR protein promotes the reaction [Calcifediol results in increased abundance of Lipids]20079722
D002112CalcifediolCalcifediol results in increased activity of VDR protein17997857|2129155
D002112CalcifediolCalcifediol results in increased activity of VDR protein21291553
D002112CalcifediolCalcifediol results in increased activity of VDR protein17997857|2129155
D002112CalcifediolCalcifediol results in increased activity of VDR protein mutant form21291553
D007501IronIron deficiency results in increased expression of VDR mRNA20368581
C004809isopentenyl pyrophosphate2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein]15879110
C004809isopentenyl pyrophosphateGo 6976 inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein]15879110
C004809isopentenyl pyrophosphateisopentenyl pyrophosphate results in increased expression of VDR protein15879110
C004809isopentenyl pyrophosphateU 0126 inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein]15879110
C006552kaempferolkaempferol results in increased activity of VDR protein26366751
D007654KetoconazoleKetoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]]24792400
D007654KetoconazoleKetoconazole inhibits the reaction [Vitamin D analog results in increased activity of VDR protein]16280049
C074279KH 1060KH 1060 binds to VDR protein15615532
C060285lacidipinelacidipine results in increased activity of VDR protein25257666
C067713lactacystinlactacystin results in decreased degradation of VDR protein24792400
D007854LeadVDR gene polymorphism affects the abundance of Lead19515364|2069202
D007854LeadVDR gene polymorphism affects the susceptibility to Lead16487505|2246622
D007854Lead[VDR gene polymorphism co-treated with ALAD gene polymorphism] affects the abundance of Lead19515364
D007854LeadVDR gene polymorphism results in increased susceptibility to Lead22101007
D007854LeadVDR polymorphism affects the susceptibility to Lead11049814
D007854LeadVDR protein affects the susceptibility to Lead22101007
C008261lead acetatelead acetate promotes the reaction [VDR protein binds to NCOA2 protein]21229763
D008055LipidsVDR protein promotes the reaction [Calcifediol results in increased abundance of Lipids]20079722
D008070LipopolysaccharidesLipopolysaccharides inhibits the reaction [Calcitriol results in increased expression of VDR protein]15876428
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of and results in decreased activity of VDR protein15876428
D008070LipopolysaccharidesCalcitriol inhibits the reaction [[Lipopolysaccharides co-treated with Glucose] results in decreased expression of VDR mRNA]21788014
D008070LipopolysaccharidesCalcitriol inhibits the reaction [[Lipopolysaccharides co-treated with Glucose] results in decreased expression of VDR protein]21788014
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Glucose] results in decreased expression of VDR mRNA21788014
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Glucose] results in decreased expression of VDR protein21788014
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of VDR28430709
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of VDR protein21291553
D008095Lithocholic AcidHR protein inhibits the reaction [Lithocholic Acid results in increased activity of VDR protein]22466564
D008095Lithocholic AcidLithocholic Acid analog binds to and results in increased activity of VDR protein15489543|1818026
D008095Lithocholic Acid[Lithocholic Acid analog binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA18180267
D008095Lithocholic Acid[Lithocholic Acid analog binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA18180267
D008095Lithocholic AcidLithocholic Acid analog binds to VDR protein20435140
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of and results in increased localization of VDR protein20371703
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of VDR protein15489543|1557859
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of VDR protein mutant form21291553|2139701
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of VDR protein] which results in increased expression of CAMP mRNA19733911
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of VDR protein] which results in increased expression of CDH1 mRNA15489543
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA15489543|1818026
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of VDR protein] which results in increased expression of CYP3A4 mRNA15489543|1557859
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA15489543
D008095Lithocholic AcidLithocholic Acid binds to VDR protein14525957|1956268
D008095Lithocholic AcidLithocholic Acid binds to VDR protein mutant form14525957
D008095Lithocholic Acid[Lithocholic Acid binds to VDR protein] which results in decreased activity of CTNNB1 mRNA20043299
D008095Lithocholic Acid"Lithocholic Acid inhibits the reaction [1,25-dihydroxy-26,27-dimethylcholecalciferol binds to VDR protein]"20153625
D008095Lithocholic AcidLithocholic Acid inhibits the reaction [VDR protein binds to NCOR1 protein]22466564
D008095Lithocholic AcidLithocholic Acid inhibits the reaction [VDR protein binds to NCOR2 protein]21917910|2246656
D008095Lithocholic AcidLithocholic Acid metabolite results in increased activity of VDR protein27871908
D008095Lithocholic AcidLithocholic Acid promotes the reaction [VDR protein binds to CYP24A1 promoter]21917910
D008095Lithocholic AcidLithocholic Acid promotes the reaction [VDR protein binds to HR protein]22466564
D008095Lithocholic AcidLithocholic Acid promotes the reaction [VDR protein binds to NCOA1 protein]15489543|2191791
D008095Lithocholic AcidLithocholic Acid promotes the reaction [VDR protein binds to NCOR2 protein]22466564
D008095Lithocholic AcidLithocholic Acid promotes the reaction [VDR protein binds to RXRA protein]15578590|2015362
D008095Lithocholic AcidLithocholic Acid results in increased activity of VDR protein21543282|2246656
D008095Lithocholic AcidLithocholic Acid results in increased expression of and results in increased activity of VDR protein18515093
D008095Lithocholic AcidLithocholic Acid results in increased expression of VDR mRNA20006981
D008095Lithocholic AcidLithocholic Acid results in increased localization of [VDR protein co-treated with CAV1 protein]20371703
D008095Lithocholic AcidLithocholic Acid results in increased phosphorylation of VDR protein20371703
D008095Lithocholic Acidtrichostatin A inhibits the reaction [HR protein inhibits the reaction [Lithocholic Acid results in increased activity of VDR protein]]22466564
D008095Lithocholic AcidVDR protein promotes the reaction [Lithocholic Acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]18515093
D008095Lithocholic AcidVDR protein promotes the reaction [Lithocholic Acid results in increased expression of ABCB1 mRNA]19460946
D008095Lithocholic AcidVDR protein promotes the reaction [Lithocholic Acid results in increased expression of CYP3A4 mRNA]18645036
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of VDR protein21291553
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of VDR protein mutant form21291553
D008095Lithocholic AcidLithocholic Acid promotes the reaction [VDR protein binds to RXRA protein]15824121
D008095Lithocholic AcidVDR protein promotes the reaction [Lithocholic Acid results in increased expression of CYP3A4 mRNA]18645036
D008095Lithocholic AcidVDR protein promotes the reaction [Lithocholic Acid results in increased expression of CYP3A4 protein]18645036
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of VDR protein21311750
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA21311750
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of VDR protein] which results in increased expression of KLK6 mRNA21311750
D008095Lithocholic AcidLithocholic Acid binds to VDR protein19562681|2372339
D008095Lithocholic Acid[Lithocholic Acid binds to VDR protein] which affects the expression of SLC51A mRNA19562681
D008095Lithocholic Acid[Lithocholic Acid binds to VDR protein] which affects the expression of SLC51B mRNA19562681
D008095Lithocholic Acid[Lithocholic Acid binds to VDR protein] which results in increased expression of NR0B2 mRNA19562681
D008095Lithocholic AcidLithocholic Acid results in decreased expression of VDR mRNA20006981
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of VDR protein21291553
D008095Lithocholic AcidLithocholic Acid binds to VDR protein16484501
D008095Lithocholic AcidLithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP24A1 promoter]15992766
D008095Lithocholic AcidLithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP3A4 promoter]15992766
D008095Lithocholic AcidLithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which results in increased expression of ABCC3]15824121
D008095Lithocholic AcidLithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which results in increased expression of CYP3A11]15824121
D008095Lithocholic AcidLithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which results in increased expression of SULT2A2]15824121
C502354lithocholic acid acetatelithocholic acid acetate binds to and results in increased activity of VDR protein21291553
C502354lithocholic acid acetatelithocholic acid acetate analog binds to and results in increased activity of VDR protein15489543
C502354lithocholic acid acetatelithocholic acid acetate binds to and results in increased activity of and results in increased localization of VDR protein20371703
C502354lithocholic acid acetatelithocholic acid acetate binds to and results in increased activity of VDR protein15489543|1818026
C502354lithocholic acid acetatelithocholic acid acetate binds to and results in increased activity of VDR protein mutant form15489543
C502354lithocholic acid acetate[lithocholic acid acetate binds to and results in increased activity of VDR protein] which results in decreased expression of CYP7A1 mRNA19106115
C502354lithocholic acid acetate[lithocholic acid acetate binds to and results in increased activity of VDR protein] which results in increased expression of CDH1 mRNA15489543
C502354lithocholic acid acetate[lithocholic acid acetate binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA15489543|1818026
C502354lithocholic acid acetate[lithocholic acid acetate binds to and results in increased activity of VDR protein] which results in increased expression of CYP3A4 mRNA15489543
C502354lithocholic acid acetate[lithocholic acid acetate binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA15489543|1818026
C502354lithocholic acid acetatelithocholic acid acetate promotes the reaction [MAPK1 protein results in increased phosphorylation of VDR protein]20371703
C502354lithocholic acid acetatelithocholic acid acetate promotes the reaction [MAPK3 protein results in increased phosphorylation of VDR protein]20371703
C502354lithocholic acid acetatelithocholic acid acetate promotes the reaction [VDR protein binds to CYP24A1 mRNA]20371703
C502354lithocholic acid acetatelithocholic acid acetate promotes the reaction [VDR protein binds to CYP7A1 mRNA]20371703
C502354lithocholic acid acetatelithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]20371703
C502354lithocholic acid acetatelithocholic acid acetate promotes the reaction [VDR protein binds to NCOA1 protein]20371703
C502354lithocholic acid acetatelithocholic acid acetate promotes the reaction [VDR protein binds to PPARGC1A protein]20371703
C502354lithocholic acid acetatelithocholic acid acetate results in increased activity of [VDR protein co-treated with RXRA protein]20371703
C502354lithocholic acid acetate[lithocholic acid acetate results in increased activity of [VDR protein co-treated with RXRA protein]] inhibits the reaction [PPARGC1A protein results in increased expression of CYP7A1 mRNA]20371703
C502354lithocholic acid acetate[lithocholic acid acetate results in increased activity of [VDR protein co-treated with RXRA protein]] which results in decreased expression of CYP7A1 mRNA20371703
C502354lithocholic acid acetate[lithocholic acid acetate results in increased activity of [VDR protein co-treated with RXRA protein]] which results in increased expression of CYP24A1 mRNA20371703
C502354lithocholic acid acetatelithocholic acid acetate results in increased localization of [VDR protein co-treated with CAV1 protein]20371703
C502354lithocholic acid acetatelithocholic acid acetate results in increased phosphorylation of VDR protein20371703
C502354lithocholic acid acetateMAPK1 protein promotes the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]]20371703
C502354lithocholic acid acetateMAPK3 protein promotes the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]]20371703
C502354lithocholic acid acetateNCOA1 protein promotes the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]]20371703
C502354lithocholic acid acetateNCOR1 protein inhibits the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]]20371703
C502354lithocholic acid acetateNCOR1 protein inhibits the reaction [[lithocholic acid acetate results in increased activity of [VDR protein co-treated with RXRA protein]] which results in increased expression of CYP24A1 mRNA]20371703
C502354lithocholic acid acetateNCOR1 protein promotes the reaction [[lithocholic acid acetate results in increased activity of [VDR protein co-treated with RXRA protein]] inhibits the reaction [PPARGC1A protein results in increased expression of CYP7A1 mRNA]]20371703
C502354lithocholic acid acetateNCOR2 protein inhibits the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]]20371703
C502354lithocholic acid acetateNCOR2 protein inhibits the reaction [[lithocholic acid acetate results in increased activity of [VDR protein co-treated with RXRA protein]] which results in increased expression of CYP24A1 mRNA]20371703
C502354lithocholic acid acetateNCOR2 protein promotes the reaction [[lithocholic acid acetate results in increased activity of [VDR protein co-treated with RXRA protein]] inhibits the reaction [PPARGC1A protein results in increased expression of CYP7A1 mRNA]]20371703
C502354lithocholic acid acetatePPARGC1A protein promotes the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]]20371703
C502354lithocholic acid acetatePPARGC1A protein promotes the reaction [[lithocholic acid acetate results in increased activity of [VDR protein co-treated with RXRA protein]] which results in increased expression of CYP24A1 mRNA]20371703
C502354lithocholic acid acetatesaracatinib inhibits the reaction [lithocholic acid acetate results in increased phosphorylation of VDR protein]20371703
C502354lithocholic acid acetateU 0126 inhibits the reaction [lithocholic acid acetate promotes the reaction [MAPK1 protein results in increased phosphorylation of VDR protein]]20371703
C502354lithocholic acid acetateU 0126 inhibits the reaction [lithocholic acid acetate promotes the reaction [MAPK3 protein results in increased phosphorylation of VDR protein]]20371703
C502354lithocholic acid acetateU 0126 inhibits the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to CYP24A1 mRNA]]20371703
C502354lithocholic acid acetateU 0126 inhibits the reaction [MAPK1 protein promotes the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]]]20371703
C502354lithocholic acid acetateU 0126 inhibits the reaction [MAPK3 protein promotes the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]]]20371703
C502354lithocholic acid acetatelithocholic acid acetate binds to and results in increased activity of VDR protein21291553
C502354lithocholic acid acetatelithocholic acid acetate binds to and results in increased activity of VDR protein mutant form21291553
C502354lithocholic acid acetatelithocholic acid acetate binds to and results in increased activity of VDR protein21291553
C502354lithocholic acid acetatelithocholic acid acetate binds to and results in increased activity of VDR protein22474172
D008274MagnesiumMagnesium affects the expression of VDR mRNA16490722
C054218manidipinemanidipine results in increased activity of VDR protein25257666
C051883maxacalcitolmaxacalcitol affects the reaction [Calcitriol binds to VDR protein]7530193
D017258Medroxyprogesterone Acetate"VDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate]"15739035
D017258Medroxyprogesterone Acetate"VDR gene polymorphism affects the susceptibility to [Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate]"15739035
D015122MercaptopurineVDR gene polymorphism affects the susceptibility to Mercaptopurine15713801
D008628MercuryVDR gene polymorphism affects the abundance of Mercury25728017
D008687MetforminMetformin inhibits the reaction [VDR protein results in increased expression of CYP3A4 mRNA]21920351
D008727MethotrexateMethotrexate results in increased expression of VDR mRNA21678067
D008727MethotrexateVDR gene polymorphism affects the susceptibility to Methotrexate15713801
C108732methyl-beta-cyclodextrinmethyl-beta-cyclodextrin inhibits the reaction [Estradiol results in increased expression of VDR protein]15930183
C008493methylselenic acidmethylselenic acid affects the expression of VDR mRNA16928829
C568376MT19c compoundMT19c compound binds to and results in decreased activity of VDR protein21803404
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of VDR mRNA"25554681
D009355Neomycin[Cephalothin co-treated with Neomycin] results in increased expression of VDR mRNA24657338
D009532NickelNickel affects the expression of VDR mRNA14575637
D009532Nickeltrichostatin A inhibits the reaction [Nickel affects the expression of VDR mRNA]14575637
C029938nickel sulfatenickel sulfate results in increased expression of VDR mRNA17374397|2271453
D009638NorepinephrineVDR protein results in increased abundance of Norepinephrine27450565
D016912LevonorgestrelVDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of ALPL protein]12521655
D016912LevonorgestrelVDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of BGLAP protein]12521655
D019319Okadaic Acid"[1,25-dihydroxyvitamin D co-treated with Okadaic Acid] promotes the reaction [VDR protein mutant form binds to MED1 protein]"16059639
D019319Okadaic Acid"[1,25-dihydroxyvitamin D co-treated with Okadaic Acid] results in increased activity of VDR protein mutant form"16059639
D010100OxygenOxygen deficiency results in decreased expression of VDR mRNA25596134
C084656paricalcitolparicalcitol binds to and affects the activity of VDR protein16076355
C084656paricalcitolparicalcitol binds to VDR protein15898824
C084656paricalcitol[Phosphorus co-treated with paricalcitol] results in increased expression of VDR protein17715259
C084656paricalcitol[Phosphorus co-treated with paricalcitol] results in increased localization of VDR protein17715259
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of VDR mRNA26705709
C046012pentanalpentanal results in increased expression of VDR mRNA26079696
D010634PhenobarbitalPhenobarbital results in decreased expression of VDR mRNA19162173
D010710PhosphatesVDR protein affects the reaction [FGF23 protein results in decreased transport of [Sodium co-treated with Phosphates]]16076377
D010758PhosphorusPhosphorus affects the expression of VDR protein17715259
D010758Phosphorus[Phosphorus co-treated with paricalcitol] results in increased expression of VDR protein17715259
D010758Phosphorus[Phosphorus co-treated with paricalcitol] results in increased localization of VDR protein17715259
D016226Phosphorus, Dietary"Phosphorus, Dietary affects the expression of VDR mRNA"15166007
D016226Phosphorus, Dietary"Phosphorus, Dietary affects the expression of VDR mRNA"15877868
D016226Phosphorus, Dietary"Phosphorus, Dietary affects the expression of VDR mRNA"16311027
D010862PilocarpinePilocarpine results in increased expression of VDR mRNA18534255
C006253pirinixic acid[Calcitriol co-treated with pirinixic acid] results in increased expression of VDR mRNA19667161
C006253pirinixic acidpirinixic acid results in increased expression of VDR mRNA19667161
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of VDR mRNA22714537
D011241PrednisonePrednisone results in increased expression of VDR protein7662588
D011241PrednisoneVDR gene polymorphism affects the susceptibility to Prednisone15713801
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione promotes the reaction [Calcitriol results in increased expression of VDR protein]"17959142
C025168previtamin D(3)previtamin D(3) analog binds to VDR protein12829710
C005556propionaldehydepropionaldehyde results in increased expression of VDR mRNA26079696
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Estradiol results in increased expression of VDR protein]15930183
C428725pyridabenpyridaben results in increased activity of VDR protein20143881
D011794QuercetinQuercetin results in increased activity of VDR protein26366751
D011794QuercetinVDR promotes the reaction [Quercetin results in increased expression of ABCB1 mRNA]26366751
D011794QuercetinVDR promotes the reaction [Quercetin results in increased expression of CYP24A1 mRNA]26366751
D011794QuercetinVDR promotes the reaction [Quercetin results in increased expression of CYP3A4 mRNA]26366751
D011794QuercetinVDR promotes the reaction [Quercetin results in increased expression of TRPV6 mRNA]26366751
D011794QuercetinVDR results in increased susceptibility to Quercetin26366751
C502851quinocetonequinocetone results in decreased expression of VDR mRNA27046791
D020849Raloxifene HydrochlorideVDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Raloxifene Hydrochloride]15739035
D020849Raloxifene HydrochlorideVDR gene polymorphism affects the susceptibility to Raloxifene Hydrochloride15739035|1660447
C059514resveratrol[Calcitriol co-treated with resveratrol] results in increased expression of VDR mRNA16267019
C059514resveratrolESR1 protein affects the reaction [resveratrol results in increased expression of VDR mRNA]15664452
C059514resveratrolresveratrol results in increased expression of and results in increased activity of VDR protein12710998
C059514resveratrolresveratrol results in increased expression of VDR mRNA12710998|1528065
C059514resveratrolresveratrol results in increased expression of VDR protein12710998
C059514resveratrolTamoxifen inhibits the reaction [resveratrol results in increased expression of VDR mRNA]12710998
D012402RotenoneRotenone results in increased activity of VDR protein20143881
C018381salvinCalcitriol promotes the reaction [salvin results in increased expression of VDR protein]11504768
C018381salvinsalvin results in increased expression of VDR protein11504768
C018381salvinTetradecanoylphorbol Acetate promotes the reaction [salvin results in increased expression of VDR protein]11504768
C018381salvinTretinoin promotes the reaction [salvin results in increased expression of VDR protein]11504768
C515233saracatinibsaracatinib inhibits the reaction [Calcitriol results in increased phosphorylation of VDR protein]20371703
C515233saracatinibsaracatinib inhibits the reaction [lithocholic acid acetate results in increased phosphorylation of VDR protein]20371703
D012632SecosteroidsSecosteroids binds to and results in increased activity of VDR protein16054704
C078903seocalcitolseocalcitol inhibits the reaction [Calcitriol binds to VDR protein]7530193
C078903seocalcitolseocalcitol results in increased activity of VDR protein16280049
C078903seocalcitolseocalcitol results in increased expression of VDR mRNA21843606
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of VDR mRNA25895662
D019821SimvastatinSimvastatin results in increased expression of VDR mRNA19262002
D012964SodiumVDR protein affects the reaction [FGF23 protein results in decreased transport of [Sodium co-treated with Phosphates]]16076377
C017947sodium arsenitesodium arsenite results in increased expression of VDR mRNA22714537
D018038Sodium SeleniteSodium Selenite results in decreased expression of VDR mRNA16928829
D053260SootSoot results in increased expression of VDR mRNA26551751
D019311StaurosporineStaurosporine results in increased cleavage of VDR protein18832097
D013481SuperoxidesVDR protein results in decreased abundance of Superoxides25201890
D013498SuraminSuramin inhibits the reaction [Estradiol results in increased expression of VDR protein]15930183
D013629TamoxifenTamoxifen inhibits the reaction [Genistein results in increased expression of VDR mRNA]12710998
D013629TamoxifenTamoxifen inhibits the reaction [resveratrol results in increased expression of VDR mRNA]12710998
D013629TamoxifenTamoxifen inhibits the reaction [Estradiol results in increased expression of VDR protein]1315250
C400545TEI 9647TEI 9647 analog binds to and affects the activity of VDR protein17125259
C012568terbufosVDR gene SNP affects the susceptibility to terbufos23833127
D013749Tetrachlorodibenzodioxin[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of VDR mRNA26159488
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of VDR mRNA20106945|2290382
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of VDR mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to VDR promoter]19654925
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of VDR mRNA24035824
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of VDR mRNA15667827|2405805
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate promotes the reaction [salvin results in increased expression of VDR protein]11504768
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of VDR mRNA20006981
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of VDR protein9348195
D013755Tetradecanoylphorbol Acetatebisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA]20006981
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of VDR mRNA20006981
D013974ThyroxineThyroxine results in increased expression of VDR mRNA17403546
D024505TocopherolsTocopherols results in increased expression of VDR mRNA12032296
C496197trans-10,cis-12-conjugated linoleic acid"trans-10,cis-12-conjugated linoleic acid results in increased expression of VDR mRNA"17951470
D014212TretinoinTretinoin results in increased expression of VDR mRNA15977162
D014212Tretinoin[Cholecalciferol co-treated with Tretinoin] promotes the reaction [[VDR protein binds to RXRA protein] which binds to SLCO1A2 promoter]22474172
D014212Tretinoin[Tretinoin co-treated with VDR protein] results in increased expression of TH protein26210580
D014212TretinoinTretinoin promotes the reaction [salvin results in increased expression of VDR protein]11504768
D014212TretinoinTretinoin results in increased expression of VDR protein7662588
C012589trichostatin A[decitabine co-treated with trichostatin A] results in increased expression of VDR mRNA17891453
C012589trichostatin A[decitabine co-treated with trichostatin A] results in increased expression of VDR protein17891453
C012589trichostatin Atrichostatin A inhibits the reaction [HR protein inhibits the reaction [Calcitriol results in increased activity of VDR protein]]22466564
C012589trichostatin Atrichostatin A inhibits the reaction [HR protein inhibits the reaction [Lithocholic Acid results in increased activity of VDR protein]]22466564
C012589trichostatin Atrichostatin A inhibits the reaction [Nickel affects the expression of VDR mRNA]14575637
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of VDR mRNA19042947
C057693troglitazonetroglitazone results in decreased expression of VDR mRNA19122273
C057693troglitazonetroglitazone results in increased expression of VDR mRNA19122273
C057693troglitazonetroglitazone inhibits the reaction [BMP2 protein results in increased expression of VDR mRNA]19122273
C113580U 0126"[1,25-dihydroxyvitamin D co-treated with U 0126] results in increased expression of VDR protein"15331595
C113580U 0126U 0126 affects the activity of VDR protein15331595
C113580U 0126U 0126 inhibits the reaction [Calcitriol promotes the reaction [MAPK1 protein results in increased phosphorylation of VDR protein]]20371703
C113580U 0126U 0126 inhibits the reaction [Calcitriol promotes the reaction [MAPK3 protein results in increased phosphorylation of VDR protein]]20371703
C113580U 0126U 0126 inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 mRNA]]20371703
C113580U 0126U 0126 inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP7A1 mRNA]]20371703
C113580U 0126U 0126 inhibits the reaction [Estradiol results in increased expression of VDR protein]17088408
C113580U 0126U 0126 inhibits the reaction [Genistein results in increased expression of VDR protein]17088408
C113580U 0126U 0126 inhibits the reaction [glycitein results in increased expression of VDR protein]17088408
C113580U 0126U 0126 inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein]15879110
C113580U 0126U 0126 inhibits the reaction [lithocholic acid acetate promotes the reaction [MAPK1 protein results in increased phosphorylation of VDR protein]]20371703
C113580U 0126U 0126 inhibits the reaction [lithocholic acid acetate promotes the reaction [MAPK3 protein results in increased phosphorylation of VDR protein]]20371703
C113580U 0126U 0126 inhibits the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to CYP24A1 mRNA]]20371703
C113580U 0126U 0126 inhibits the reaction [MAPK1 protein promotes the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]]20371703
C113580U 0126U 0126 inhibits the reaction [MAPK1 protein promotes the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]]]20371703
C113580U 0126U 0126 inhibits the reaction [MAPK3 protein promotes the reaction [Calcitriol promotes the reaction [VDR protein binds to HNF4A protein]]]20371703
C113580U 0126U 0126 inhibits the reaction [MAPK3 protein promotes the reaction [lithocholic acid acetate promotes the reaction [VDR protein binds to HNF4A protein]]]20371703
C113580U 0126U 0126 results in increased expression of VDR mRNA24819614
D014501UraniumUranium results in decreased expression of VDR mRNA17118558
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VDR mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of VDR mRNA25979313
D014635Valproic Acid[Valproic Acid co-treated with VDR protein] results in increased expression of CYP24A1 mRNA21115105
D014635Valproic AcidValproic Acid promotes the reaction [[Calcitriol co-treated with VDR protein] results in increased expression of CYP24A1 mRNA]21115105
D014635Valproic AcidValproic Acid results in increased expression of VDR mRNA23179753|2438349
D014638VanadatesVanadates results in increased expression of VDR mRNA22714537
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of VDR gene25560391
D014750VincristineVDR gene polymorphism affects the susceptibility to Vincristine15713801
D014807Vitamin DKetoconazole inhibits the reaction [Vitamin D analog results in increased activity of VDR protein]16280049
D014807Vitamin DVitamin D analog inhibits the reaction [VDR protein binds to CYP24A1 promoter]21917910
D014807Vitamin DVitamin D analog inhibits the reaction [VDR protein binds to NCOR2 protein]21917910
D014807Vitamin DVitamin D analog promotes the reaction [[NCOR2 protein binds to VDR protein] which binds to CYP24A1 promoter]21917910
D014807Vitamin DVitamin D analog promotes the reaction [VDR protein binds to NCOA1 protein]21917910
D014807Vitamin DVitamin D analog promotes the reaction [VDR protein binds to RXRA protein]21917910
D014807Vitamin DVitamin D analog results in increased activity of VDR protein16280049
D014807Vitamin DVitamin D binds to and affects the activity of VDR protein21917910
D014807Vitamin DVitamin D deficiency results in increased expression of VDR protein9525346
D002762CholecalciferolCholecalciferol binds to and results in increased activity of VDR protein mutant form21397016
D002762Cholecalciferol[Cholecalciferol binds to VDR protein] which results in increased expression of SLCO1A2 mRNA22474172
D002762Cholecalciferol[Cholecalciferol co-treated with Tretinoin] promotes the reaction [[VDR protein binds to RXRA protein] which binds to SLCO1A2 promoter]22474172
D002762CholecalciferolCholecalciferol promotes the reaction [Fenretinide results in increased expression of VDR]17024972
D002762CholecalciferolCholecalciferol promotes the reaction [VDR protein binds to SLCO1A2 promoter]22474172
D002762CholecalciferolCholecalciferol promotes the reaction [[VDR protein binds to SLCO1A2 promoter] which results in increased expression of SLCO1A2 mRNA]22474172
D002762CholecalciferolCholecalciferol results in increased expression of VDR17024972
D002762CholecalciferolVDR protein affects the reaction [Cholecalciferol results in increased expression of SLCO1A2 mRNA]22474172
D002762CholecalciferolCholecalciferol inhibits the reaction [[Hexachlorobenzene co-treated with Diethylnitrosamine] results in increased expression of VDR protein]28634113
D002762CholecalciferolCholecalciferol promotes the reaction [[RXRB protein binds to VDR protein] which binds to TNFSF11 promoter]17008384
D002762CholecalciferolCholecalciferol analog binds to and affects the activity of VDR protein16055325
D002762CholecalciferolCholecalciferol analog binds to and results in increased activity of VDR protein15988762
D002762CholecalciferolCholecalciferol binds to and affects the activity of VDR protein16055325
D015215Zidovudine[Zidovudine co-treated with Lamivudine] results in decreased expression of VDR mRNA11741158
D015032ZincZinc deficiency results in increased activity of VDR protein18356318
C017803zinc protoporphyrinVDR gene polymorphism affects the abundance of zinc protoporphyrin25963508
C410228ZK159222ZK159222 inhibits the reaction [Calcitriol results in increased expression of VDR mRNA]15922086
C410228ZK159222ZK159222 inhibits the reaction [Calcitriol results in increased expression of VDR protein]15922086
C417690ZK 168281ZK 168281 binds to and results in decreased activity of VDR protein15905360

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000976transcription regulatory region sequence-specific DNA binding-IBA21873635  
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding-IBA21873635  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0001076transcription factor activity, RNA polymerase II transcription factor binding-IBA21873635  
GO:0003677DNA binding-IDA11891224  
GO:0003700DNA-binding transcription factor activityCONTRIBUTES_TOIBA21873635  
GO:0003700DNA-binding transcription factor activitycontributes_toIDA17426122  
GO:0003707steroid hormone receptor activity-IEA-  
GO:0004879nuclear receptor activity-IBA21873635  
GO:0005499vitamin D binding-IBA21873635  
GO:0005515protein binding-IPI9632709  9653119  10409738  10744685  10866662  12840015  
17254542  17426122  20089040  20227041  20413580  21119599  
21478865  21988832  22179700  25910212  27728806  
GO:0008134transcription factor binding-IBA21873635  
GO:0008270zinc ion binding-IEA-  
GO:0008434calcitriol receptor activity-IBA21873635  
GO:0008434calcitriol receptor activity-IDA12016314  16549446  17082781  
GO:0008434calcitriol receptor activity-IMP28698609  
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity-IBA21873635  
GO:0038186lithocholic acid receptor activity-IDA12016314  
GO:0046965retinoid X receptor binding-IDA28698609  
GO:0046965retinoid X receptor binding-IPI17426122  
GO:0070644vitamin D response element bindingCONTRIBUTES_TOIBA21873635  
GO:0070644vitamin D response element bindingcontributes_toIDA17426122  
GO:0098531transcription factor activity, direct ligand regulated sequence-specific DNA binding-IBA21873635  
GO:1902098calcitriol binding-IBA21873635  
GO:1902098calcitriol binding-IDA10678179  12016314  
GO:1902098calcitriol binding-IMP28698609  
GO:1902121lithocholic acid binding-IDA12016314  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IDA17426122  
GO:0000902cell morphogenesis-IMP17223341  
GO:0001501skeletal system development-IEA-  
GO:0006367transcription initiation from RNA polymerase II promoter-TAS-  
GO:0006816calcium ion transport-IEA-  
GO:0006874cellular calcium ion homeostasis-IEA-  
GO:0007165signal transduction-TAS2849209  
GO:0007275multicellular organism development-IBA21873635  
GO:0007595lactation-IEA-  
GO:0008285negative regulation of cell proliferation-IDA16549446  
GO:0009887animal organ morphogenesis-IBA21873635  
GO:0010628positive regulation of gene expression-IMP17223341  
GO:0010839negative regulation of keratinocyte proliferation-IMP17223341  
GO:0010980positive regulation of vitamin D 24-hydroxylase activity-IDA16549446  
GO:0030154cell differentiation-IBA21873635  
GO:0038183bile acid signaling pathway-IDA12016314  
GO:0042359vitamin D metabolic process-TAS-  
GO:0043401steroid hormone mediated signaling pathway-IEA-  
GO:0045618positive regulation of keratinocyte differentiation-IMP17082781  
GO:0045892negative regulation of transcription, DNA-templated-IDA11891224  
GO:0045944positive regulation of transcription by RNA polymerase II-IBA21873635  
GO:0045944positive regulation of transcription by RNA polymerase II-IMP17082781  17254542  
GO:0046697decidualization-IEP16720713  
GO:0050892intestinal absorption-IEA-  
GO:0060058positive regulation of apoptotic process involved in mammary gland involution-IEA-  
GO:0060429epithelium development-IBA21873635  
GO:0060558regulation of calcidiol 1-monooxygenase activity-ISS-  
GO:0060745mammary gland branching involved in pregnancy-IEA-  
GO:0070561vitamin D receptor signaling pathway-IDA16549446  
GO:0070561vitamin D receptor signaling pathway-IMP28698609  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA15589699  17082781  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IEA-  
GO:0043235receptor complex-IDA17426122  
GO:0090575RNA polymerase II transcription factor complex-IBA21873635  
GO:0090575RNA polymerase II transcription factor complex-IDA17426122  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-196791Vitamin D (calciferol) metabolismTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-383280Nuclear Receptor transcription pathwayTAS
R-HSA-556833Metabolism of lipidsTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8957322Metabolism of steroidsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18194505Low body mass not vitamin D receptor polymorphisms predict osteoporosis in patients with inflammatory bowel disease. (2008 Apr 1)Noble CLAliment Pharmacol Ther
22242137Prognostic significance of vitamin D receptor polymorphisms in head and neck squamous cell carcinoma. (2011)Hama TPLoS One
11890577Moderate physical activity is associated with higher bone mineral density in postmenopausal women. (2001 Nov)Hagberg JMJ Am Geriatr Soc
12666703Vitamin D receptor alleles, periodontal disease progression, and tooth loss in the VA dental longitudinal study. (2003 Feb)Inagaki KJ Periodontol
25498546Genetic variants of vitamin D receptor and susceptibility to ischemic stroke. (2015 Jan 9)Prabhakar PBiochem Biophys Res Commun
23975061Matrix metalloproteinase-3, vitamin D receptor gene polymorphisms, and occupational risk factors in lumbar disc degeneration. (2014 Jun)Zawilla NHJ Occup Rehabil
17211561Clinical risk factors and the role of VDR gene polymorphisms in diabetic retinopathy in Polish type 2 diabetes patients. (2006 Dec)Cyganek KActa Diabetol
28029444Associations between Serum Vitamin D and Genetic Variants in Vitamin D Pathways and Age-Related Macular Degeneration in the European Eye Study. (2017 Jan)McKay GJOphthalmology
29608804Relationship between vitamin D receptor gene polymorphism and susceptibility to chronic kidney disease and periodontal disease in community-dwelling elderly. (2018 Apr 2)Yoshihara AJ Clin Periodontol
25177835A molecular prospective provides new insights into implication of PDYN and OPRK1 genes in alcohol dependence. (2014 Oct)Faisal MComput Biol Med
28380424Association of VEGF and VDR gene- gene and gene- smoking interaction on risk of multiple myeloma in Chinese Han population. (2017 May 30)Chen POncotarget
18662591Association of the polymorphisms of MTHFR C677T, VDR C352T, and MPO G463A with risk for esophageal squamous cell dysplasia and carcinoma. (2008 Aug)Li DArch Med Res
21916886Calcium homeostasis and body composition in patients with palmoplantar pustulosis: a case-control study. (2012 Jan)Hagforsen EBr J Dermatol
25671813Gender differences in the VDR-FokI polymorphism and conventional non-genetic risk factors in association with lumbar spine pathologies in an Italian case-control study. (2015 Feb 9)Colombini AInt J Mol Sci
24996287Association of vitamin D receptor FokI and ApaI polymorphisms with lung cancer risk in Tunisian population. (2014 Oct)Kaabachi WMol Biol Rep
8889857Determinants of premenopausal bone mineral density: the interplay of genetic and lifestyle factors. (1996 Oct)Salamone LMJ Bone Miner Res
7502697Vitamin D receptor gene polymorphisms do not predict bone turnover and bone mass in healthy premenopausal women. (1995 Sep)Garnero PJ Bone Miner Res
25078595Vitamin D receptor genetic variants are associated with susceptibility of gallbladder adenocarcinoma in a Chinese cohort. (2014 Jul 24)Li ZGenet Mol Res
23403039Active Crohn's disease is associated with low vitamin D levels. (2013 Nov)Jorgensen SPJ Crohns Colitis
29744169Inflammatory mediator polymorphisms associate with initial periodontitis in adolescents. (2016 Dec)Heikkinen AMClin Exp Dent Res
18410395Vitamin D receptor polymorphism (-1056 Taq-I) interacts with smoking for the presence and progression of periodontitis. (2008 Jul)Nibali LJ Clin Periodontol
9761785Putative susceptibility markers of coronary artery disease: association between VDR genotype, smoking, and aromatic DNA adduct levels in human right atrial tissue. (1998 Oct)Van Schooten FJFASEB J
25059118Association between Fok I vitamin D receptor gene (VDR) polymorphism and impulsivity in alcohol-dependent patients. (2014 Nov)Wrzosek MMol Biol Rep
25196087Vitamin D receptor genetic polymorphism is significantly associated with decreased risk of hypertension in a Chinese Han population. (2014 Sep)Jia JJ Clin Hypertens (Greenwich)
27669215Vitamin D-Related Gene Polymorphisms, Plasma 25-Hydroxy-Vitamin D, Cigarette Smoke and Non-Small Cell Lung Cancer (NSCLC) Risk. (2016 Sep 22)Wu XInt J Mol Sci
8781042Common polymorphism of the vitamin D receptor gene is associated with variation of peak bone mass in young finns. (1996 Oct)Viitanen ACalcif Tissue Int
21048058Vitamin D receptor gene polymorphisms are associated with adiposity phenotypes. (2011 Jan)Ochs-Balcom HMAm J Clin Nutr
28266114Interaction of lifestyle, behaviour or systemic diseases with dental caries and periodontal diseases: consensus report of group 2 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases. (2017 Mar)Chapple ILJ Clin Periodontol
24568525Lack of associations between Vitamin D metabolism-related gene variants and risk of colorectal cancer. (2014)Mahmoudi TAsian Pac J Cancer Prev
27358421Vitamin D Receptor Gene Polymorphisms Are Associated with Abdominal Visceral Adipose Tissue Volume and Serum Adipokine Concentrations but Not with Body Mass Index or Waist Circumference in African Americans: The Jackson Heart Study. (2016 Aug)Khan RJJ Nutr
21132374Start codon FokI and intron 8 BsmI variants in the vitamin D receptor gene and susceptibility to colorectal cancer. (2011 Oct)Mahmoudi TMol Biol Rep
28411367Serum 25(OH)D concentration, common variants of the VDR gene and lung cancer occurrence. (2017 Jul 15)Gromowski TInt J Cancer
15316869Vitamin D receptor gene start codon polymorphism (FokI) is associated with forearm bone mineral density and calcaneal ultrasound in Finnish adolescent boys but not in girls. (2004)Laaksonen MMJ Bone Miner Metab
16009674Influence of IL-6, COL1A1, and VDR gene polymorphisms on bone mineral density in Crohn's disease. (2005 Nov)Todhunter CEGut
11533996Vitamin D receptor polymorphisms and bone mineral density in Mexican women without osteoporosis. (1999 Nov)Jaramillo-Rangel GAm J Hum Biol
24810167FokI polymorphism in the vitamin D receptor gene (VDR) and its association with lumbar spine pathologies in the Italian population: a case-control study. (2014)Colombini APLoS One
19244278The aryl hydrocarbon receptor activator benzo[a]pyrene enhances vitamin D3 catabolism in macrophages. (2009 May)Matsunawa MToxicol Sci
28700743Polymorphisms in the vitamin D receptor gene are associated with reduced rate of sputum culture conversion in multidrug-resistant tuberculosis patients in South Africa. (2017)Magee MJPLoS One
15308833Investigations of vitamin D receptor polymorphism affecting workers' susceptibility to lead. (2004 Jul)Chuang HYJ Occup Health
28184307Low back pain and FokI (rs2228570) polymorphism of vitamin D receptor in athletes. (2017)Cauci SBMC Sports Sci Med Rehabil
26347716Vitamin D receptor and epigenetics in HIV infection and drug abuse. (2015)Chandel NFront Microbiol
12588283Vitamin D receptor gene polymorphism BsmI is not associated with the prevalence and severity of CAD in a large-scale angiographic cohort of 3441 patients. (2003 Feb)Ortlepp JREur J Clin Invest
24068566Polymorphisms in the vitamin D receptor gene and the lung cancer risk. (2014 Feb)Fu YTumour Biol
28009432Genetic polymorphisms of vitamin D receptor (VDR), CYP27B1 and CYP24A1 genes and the risk of colorectal cancer. (2017 May 4)Vidigal VMInt J Biol Markers
27491013Vitamin D Receptor Gene Polymorphism and Smoking in the Risk of Chronic Periodontitis. (2016 Nov)Chantarangsu SJ Periodontol
10367040Polymorphism of the vitamin D receptor gene and corticosteroid-related osteoporosis. (1999)Ho YVOsteoporos Int
23841669VDR gene polymorphisms, interaction with smoking and risk of periodontal disease in Japanese women: the Kyushu Okinawa maternal and child health study. (2013 Oct)Tanaka KScand J Immunol
22167329The -4817 G>A (rs2238136) variant of the vitamin D receptor gene: a probable risk factor for colorectal cancer. (2012 May)Mahmoudi TMol Biol Rep
28471875Genetic predictors of recovery in low back and lumbar radicular pain. (2017 Aug)Bjorland SPain
29467039Influence of lifestyle characteristics and VDR polymorphisms as risk factors for intervertebral disc degeneration: a case-control study. (2018 Feb 21)Vieira LAEur J Med Res
22345993Risk conferred by FokI polymorphism of vitamin D receptor (VDR) gene for essential hypertension. (2011 Sep)Swapna NIndian J Hum Genet
20236614Myocardial effects of VDR activators in renal failure. (2010 Jul)Mizobuchi MJ Steroid Biochem Mol Biol
16207551Additive effects of the chemokine receptor 2, vitamin D receptor, interleukin-6 polymorphisms and cardiovascular risk factors on the prevalence of myocardial infarction in patients below 65 years. (2005 Oct 20)Ortlepp JRInt J Cardiol
28884047BsmI (rs1544410) and FokI (rs2228570) vitamin D receptor polymorphisms, smoking, and body mass index as risk factors of cutaneous malignant melanoma in northeast Italy. (2017 Aug)Cauci SCancer Biol Med
19795209Vitamin D receptor gene ApaI polymorphism is associated with susceptibility to colorectal cancer. (2010 Jul)Mahmoudi TDig Dis Sci
21545713Vitamin D receptor gene polymorphisms in multiple sclerosis patients in northwest Greece. (2011 May 5)Sioka CJ Negat Results Biomed
17848979Association between vitamin D receptor gene haplotypes and chronic periodontitis among Japanese men. (2007 Aug 22)Naito MInt J Med Sci
16835078How valid is single nucleotide polymorphism (SNP) diagnosis for the individual risk assessment of breast cancer? (2006 Mar)Tempfer CBGynecol Endocrinol
26453801Vitamin D Receptor Genetic Polymorphism Is Significantly Associated with Risk of Type 2 Diabetes Mellitus in Chinese Han Population. (2015 Oct)Jia JArch Med Res
27989222Pilot Study on the Genetic Background of an Active Matrix Metalloproteinase-8 Test in Finnish Adolescents. (2017 May)Heikkinen AMJ Periodontol
23236317Inhibition of vitamin d receptor translocation by cigarette smoking extracts. (2012 Nov)Uh STTuberc Respir Dis (Seoul)
15917153The influence of a Vitamin D receptor gene polymorphism on the timing of female reproductive functions in humans. (2005 Jun 16)Grimm CMaturitas
16670168Vitamin D metabolism in peripheral blood mononuclear cells is influenced by chewing "betel nut" (Areca catechu) and vitamin D status. (2006 Jul)Ogunkolade WBJ Clin Endocrinol Metab
14572874Vitamin D receptor gene polymorphism is associated with chronic periodontitis. (2003 Nov 14)Tachi YLife Sci
11289690Absence of linkage for bone mineral density to chromosome 12q12-14 in the region of the vitamin D receptor gene. (2000 Dec)Zee RYCalcif Tissue Int
22155603Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration. (2011 Oct)Morrison MAHum Genomics
16965239Vitamin D receptor gene polymorphisms, dietary promotion of insulin resistance, and colon and rectal cancer. (2006)Murtaugh MANutr Cancer
20955794Nuclear vitamin D receptor expression is associated with improved survival in non-small cell lung cancer. (2011 Jan)Srinivasan MJ Steroid Biochem Mol Biol
15816500Cardiovascular disease in chronic kidney failure: is there a role for vitamin D analogs? (2005 Mar)Wu-Wong JRCurr Opin Investig Drugs
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