Gene: VEGFC

7424
Flt4-L|LMPH1D|VRP
vascular endothelial growth factor C
protein-coding
4q34.3
Ensembl:ENSG00000150630 MIM:601528 Vega:OTTHUMG00000160734 UniprotKB:P49767
NG_034216.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.696e-1 (AD)  9.594e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg27635485chr4:177630793VEGFC6.300e-8Smoking27651444

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TNFAIP80.876
TFPI0.863
ADPRH0.852
CARD60.845
MFNG0.844
MYOF0.837
PLCG20.837
FXYD50.833
ECSCR0.83
NAALADL10.828

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KCNB2-0.507
LRTM2-0.506
MYADML2-0.506
ST6GALNAC5-0.502
BCL11A-0.502
SVOP-0.497
HAS1-0.496
NEUROD6-0.493
ZNF835-0.49
SLC7A4-0.487

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of VEGFC mRNA"26377693
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of VEGFC mRNA"19114083
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of VEGFC mRNA"21346803
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Azoxymethane] results in increased expression of VEGFC mRNA"18424890
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VEGFC mRNA"23196670
C4727913-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of VEGFC mRNA16788091
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VEGFC mRNA"27188386
C0022024-oxoretinoic acid4-oxoretinoic acid results in decreased expression of VEGFC mRNA15982314
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VEGFC mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of VEGFC mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of VEGFC mRNA22100608
C103303alitretinoinalitretinoin results in decreased expression of VEGFC mRNA15982314
D000643Ammonium ChlorideAmmonium Chloride affects the expression of VEGFC mRNA16483693
D000728AndrogensAndrogens affects the expression of VEGFC mRNA16964283
D000728AndrogensAndrogens affects the reaction [RALA protein affects the expression of VEGFC mRNA]16964283
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of VEGFC mRNA24449571
D001151ArsenicArsenic results in decreased expression of VEGFC mRNA19654921
C006632arsenic trioxidearsenic trioxide results in decreased expression of VEGFC mRNA19804631
C006632arsenic trioxidearsenic trioxide results in decreased expression of VEGFC protein19099632
C006632arsenic trioxidearsenic trioxide results in increased expression of VEGFC mRNA26705709
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of VEGFC mRNA"18687144
D001397Azoxymethane"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Azoxymethane] results in increased expression of VEGFC mRNA"18424890
D001539BendroflumethiazideBendroflumethiazide results in decreased expression of VEGFC protein20625077
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of VEGFC mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of VEGFC mRNA21569818
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of VEGFC mRNA22228805|2261060
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of VEGFC mRNA"19150397
D001599BerberineBerberine results in increased expression of VEGFC mRNA26478571
C551172bis-N,N-dimethylamino-2-(N-methylpyrrolyl)methyl cyclopentadienyl titanium (IV)"bis-N,N-dimethylamino-2-(N-methylpyrrolyl)methyl cyclopentadienyl titanium (IV) results in increased expression of VEGFC mRNA"20162321
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of VEGFC mRNA28628672
C006780bisphenol Abisphenol A results in increased expression of VEGFC mRNA25181051
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of VEGFC mRNA22079614
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of VEGFC mRNA15336504|1720066
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of VEGFC protein17200665
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased secretion of VEGFC protein17200665
C018475butyraldehydebutyraldehyde results in decreased expression of VEGFC mRNA26079696
C584509C646 compoundC646 compound results in decreased expression of VEGFC mRNA26191083
D002101Cacodylic AcidCacodylic Acid results in increased expression of VEGFC mRNA17441966
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of VEGFC mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of VEGFC mRNA12734012
C010063carbonyl sulfidecarbonyl sulfide results in increased expression of VEGFC mRNA19395590
D002752ChlorthalidoneChlorthalidone results in decreased expression of VEGFC mRNA20625077
D002752ChlorthalidoneChlorthalidone results in decreased expression of VEGFC protein20625077
D002752ChlorthalidoneChlorthalidone results in increased expression of VEGFC protein20625077
D002994ClofibrateClofibrate results in increased expression of VEGFC mRNA16081524
C034456CMF regimenVEGFC mRNA results in increased susceptibility to [Paclitaxel co-treated with Epirubicin co-treated with CMF regimen]23146280
D060729Coal AshCoal Ash results in decreased expression of VEGFC mRNA19000753
C018021cobaltous chloridecobaltous chloride results in decreased expression of VEGFC mRNA19320972|1937684
D003300Copper[Disulfiram binds to Copper] which results in increased expression of VEGFC mRNA24690739
D003300Copper[Organoselenium Compounds binds to Copper] which results in decreased expression of VEGFC mRNA25167922
D003300Copper[ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of VEGFC mRNA15467011
C402665CP 31398CP 31398 results in increased expression of VEGFC mRNA15155752
C072247cyclo(Trp-Asp-Pro-Val-Leu)cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [VEGFC protein results in decreased expression of CDKN1B protein]24184161
C072247cyclo(Trp-Asp-Pro-Val-Leu)cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [VEGFC protein results in increased expression of CCNE2 protein]24184161
C072247cyclo(Trp-Asp-Pro-Val-Leu)cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [VEGFC protein results in increased expression of CDK2 protein]24184161
C072247cyclo(Trp-Asp-Pro-Val-Leu)cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [VEGFC protein results in increased expression of PTGS2 protein]24184161
C017160cypermethrincypermethrin results in decreased expression of VEGFC mRNA22528246
D003561CytarabineEDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]24184161
D003561CytarabinePTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]24184161
D003561CytarabineVEGFC protein results in decreased susceptibility to Cytarabine24184161
D003561CytarabineEDN1 mutant form affects the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]24184161
D003561CytarabinePTGS2 mutant form affects the reaction [VEGFC protein results in decreased susceptibility to Cytarabine]24184161
D003561CytarabineVEGFC protein results in decreased susceptibility to Cytarabine24184161
C576677demycarosyl-3D-digitoxosylmithramycin SKdemycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of VEGFC mRNA24907531
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of VEGFC mRNA28628672
D003976DiazinonDiazinon affects the expression of VEGFC mRNA22546817
D004026DieldrinDieldrin affects the expression of VEGFC mRNA22546817
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate affects the expression of VEGFC mRNA20920545
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in decreased expression of VEGFC mRNA27638505
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of VEGFC mRNA25617811
D004221Disulfiram[Disulfiram binds to Copper] which results in increased expression of VEGFC mRNA24690739
D004317DoxorubicinVEGFC protein affects the susceptibility to Doxorubicin16217747
D015251EpirubicinVEGFC mRNA results in increased susceptibility to [Paclitaxel co-treated with Epirubicin co-treated with CMF regimen]23146280
D005047EtoposideEDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide]24184161
D005047EtoposidePTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide]24184161
D005047EtoposideVEGFC protein results in decreased susceptibility to Etoposide24184161
D005485FlutamideFlutamide results in decreased expression of VEGFC mRNA21126777
D005485FlutamideFlutamide results in increased expression of VEGFC mRNA24136188|2479361
D004397FonofosFonofos results in increased methylation of VEGFC promoter22847954
D005557FormaldehydeFormaldehyde results in increased expression of VEGFC mRNA25617811
D005665FurosemideFurosemide results in increased expression of VEGFC mRNA16526316
D019833GenisteinGenistein results in decreased expression of VEGFC mRNA22228119
C004312glycidolglycidol results in decreased expression of VEGFC mRNA24915197
C409722hexaconazolehexaconazole results in decreased expression of VEGFC mRNA22045034
D017313FenretinideFenretinide results in increased expression of VEGFC mRNA28973697
D006851Hydrochloric AcidHydrochloric Acid results in increased expression of VEGFC mRNA15046208
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of VEGFC mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of VEGFC mRNA28628672
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of VEGFC protein17337753
C561695(+)-JQ1 compound[(+)-JQ1 compound co-treated with PD 0325901] results in decreased expression of VEGFC mRNA25119042
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of VEGFC mRNA24796395|2511904
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of VEGFC mRNA"24972896
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of VEGFC mRNA25613284
D019808LosartanLosartan results in decreased expression of VEGFC mRNA19771429
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in increased expression of VEGFC mRNA21641980
C025340manganese chloridemanganese chloride results in increased expression of VEGFC mRNA17467022
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of VEGFC mRNA26011545
C008493methylselenic acidmethylselenic acid results in decreased expression of VEGFC mRNA12517777
C043243methyl tert-butyl ethermethyl tert-butyl ether results in decreased expression of VEGFC mRNA21684239|2260974
C043243methyl tert-butyl etherVEGFAA protein inhibits the reaction [methyl tert-butyl ether results in decreased expression of VEGFC mRNA]24128854
C043243methyl tert-butyl etherVHL mutant form inhibits the reaction [methyl tert-butyl ether results in decreased expression of VEGFC mRNA]24128854
D008911MinocyclineMinocycline inhibits the reaction [Oxygen deficiency results in increased expression of VEGFC mRNA]24292262
C066851mithramycin Amithramycin A results in decreased expression of VEGFC mRNA24907531
C520007mithramycin SKmithramycin SK results in decreased expression of VEGFC mRNA24907531
D009151Mustard GasIL10 protein affects the reaction [Mustard Gas affects the expression of VEGFC mRNA]16173061
D009151Mustard GasMustard Gas results in decreased expression of VEGFC mRNA25102026
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFC protein results in decreased expression of CDKN1B protein]24184161
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFC protein results in increased expression of CCNE2 protein]24184161
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [VEGFC protein results in increased expression of CDK2 protein]24184161
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of VEGFC mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of VEGFC mRNA"25554681
C005274naringinnaringin affects the expression of VEGFC mRNA24880026
C022838nickel chloridenickel chloride results in increased expression of VEGFC mRNA17312168
C022838nickel chloridenickel chloride affects the expression of VEGFC mRNA22546817
C012655nimesulidenimesulide results in decreased expression of VEGFC mRNA18509974
C012655nimesulidenimesulide results in decreased expression of VEGFC protein18509974
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of VEGFC mRNA16777990
C014707nitrosobenzylmethylaminePlant Preparations inhibits the reaction [nitrosobenzylmethylamine results in increased expression of VEGFC mRNA]16777990
D016566Organoselenium Compounds[Organoselenium Compounds binds to Copper] which results in decreased expression of VEGFC mRNA25167922
C510784ormosil[ormosil binds to Polyethylene Glycols] which results in increased expression of VEGFC mRNA24888373
D010047Ovalbumin[Particulate Matter co-treated with Ovalbumin] results in increased expression of VEGFC mRNA19176365
C030110oxaliplatinoxaliplatin results in increased expression of VEGFC protein18790786
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of VEGFC mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of VEGFC mRNA25729387
D010100OxygenMinocycline inhibits the reaction [Oxygen deficiency results in increased expression of VEGFC mRNA]24292262
D010100OxygenOxygen deficiency results in increased expression of VEGFC mRNA24292262|2651600
D017239PaclitaxelVEGFC mRNA results in increased susceptibility to [Paclitaxel co-treated with Epirubicin co-treated with CMF regimen]23146280
D010278ParathionParathion results in increased methylation of VEGFC promoter22847954
D052638Particulate Matter[Particulate Matter co-treated with Ovalbumin] results in increased expression of VEGFC mRNA19176365
C506614PD 0325901[(+)-JQ1 compound co-treated with PD 0325901] results in decreased expression of VEGFC mRNA25119042
C506614PD 0325901PD 0325901 results in decreased expression of VEGFC mRNA25119042
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of VEGFC mRNA26705709
D015232DinoprostoneDinoprostone results in decreased expression of VEGFC mRNA18509974
D015232DinoprostoneDinoprostone results in decreased expression of VEGFC protein18509974
D028321Plant PreparationsPlant Preparations inhibits the reaction [nitrosobenzylmethylamine results in increased expression of VEGFC mRNA]16777990
D011092Polyethylene Glycols[ormosil binds to Polyethylene Glycols] which results in increased expression of VEGFC mRNA24888373
D011441PropylthiouracilPropylthiouracil results in increased expression of VEGFC mRNA24780913
C059514resveratrolresveratrol inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of VEGFC mRNA]24729934
C059514resveratrolresveratrol inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased secretion of VEGFC protein]24729934
D015474IsotretinoinIsotretinoin results in decreased expression of VEGFC mRNA15982314
C078903seocalcitolseocalcitol results in decreased expression of VEGFC mRNA12040012
D000068677Sildenafil CitrateSildenafil Citrate results in increased expression of VEGFC mRNA20583517
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of VEGFC mRNA23806026
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of VEGFC mRNA25895662
D012967Sodium Dodecyl SulfateSodium Dodecyl Sulfate results in increased expression of VEGFC mRNA25617811
D012969Sodium FluorideSodium Fluoride results in increased expression of VEGFC mRNA27862939
D018038Sodium SeleniteSodium Selenite results in increased expression of VEGFC mRNA24383545
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in increased expression of VEGFC mRNA21641980
C016767sulprostonesulprostone results in increased expression of VEGFC mRNA20335389
C473478sunitinibsunitinib results in decreased expression of VEGFC protein18669461
C087114tebuconazoletebuconazole results in decreased expression of VEGFC mRNA26852204
C012568terbufosterbufos results in increased methylation of VEGFC promoter22847954
D013749TetrachlorodibenzodioxinAHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFC mRNA]16214954
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of VEGFC mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of VEGFC mRNA12167310|1621495
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of VEGFC mRNA20558275
D013806TheophyllineTheophylline results in increased expression of VEGFC mRNA16083514
C009495titanium dioxidetitanium dioxide results in decreased expression of VEGFC mRNA23557971|2776080
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of VEGFC mRNA25729387
D019772TopotecanTopotecan results in increased expression of VEGFC mRNA25729387
D014212TretinoinTretinoin metabolite results in increased expression of VEGFC mRNA15982314
D014212TretinoinTretinoin results in decreased expression of VEGFC mRNA15982314
D014212TretinoinTretinoin results in decreased expression of VEGFC mRNA16788091
C012589trichostatin Atrichostatin A results in increased expression of VEGFC mRNA24935251
C030665triphenyltintriphenyltin results in decreased expression of VEGFC mRNA19031914
C057693troglitazonetroglitazone results in decreased expression of VEGFC mRNA20846491
C057693troglitazonetroglitazone results in decreased expression of VEGFC mRNA28973697
C057693troglitazonetroglitazone results in increased expression of VEGFC mRNA17569031
C057693troglitazone[Urethane co-treated with troglitazone] results in increased expression of VEGFC mRNA18465119
C022884undecaneundecane results in increased expression of VEGFC protein17337753
D014520Urethane[Urethane co-treated with troglitazone] results in increased expression of VEGFC mRNA18465119
D014520UrethaneUrethane results in increased expression of VEGFC mRNA18465119
C003747urushiolurushiol results in increased expression of VEGFC mRNA25617811
D014635Valproic AcidValproic Acid results in decreased expression of VEGFC mRNA29154799
D014635Valproic AcidValproic Acid results in increased expression of VEGFC mRNA24935251
D014635Valproic AcidValproic Acid results in decreased expression of VEGFC mRNA22045034
D014747VinblastineVEGFC protein affects the susceptibility to Vinblastine16217747
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VEGFC mRNA"27188386
C111237vorinostatvorinostat results in increased expression of VEGFC mRNA26272509
D015032ZincZinc results in decreased expression of VEGFC mRNA17074742
D019287Zinc SulfateZinc Sulfate results in decreased expression of VEGFC mRNA17074742

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI20145116  21130043  
GO:0008083growth factor activity-IBA21873635  
GO:0042056chemoattractant activity-IBA21873635  
GO:0042056chemoattractant activity-IDA19275959  
GO:0043185vascular endothelial growth factor receptor 3 binding-IBA21873635  
GO:0043185vascular endothelial growth factor receptor 3 binding-IPI23878260  
GO ID GO Term Qualifier Evidence PubMed
GO:0001525angiogenesis-IBA21873635  
GO:0001666response to hypoxia-IBA21873635  
GO:0001934positive regulation of protein phosphorylation-IBA21873635  
GO:0001938positive regulation of endothelial cell proliferation-IBA21873635  
GO:0001954positive regulation of cell-matrix adhesion-IEA-  
GO:0002040sprouting angiogenesis-IBA21873635  
GO:0002052positive regulation of neuroblast proliferation-IEA-  
GO:0002576platelet degranulation-TAS-  
GO:0006929substrate-dependent cell migration-TAS8617204  
GO:0007165signal transduction-TAS8617204  
GO:0008284positive regulation of cell proliferation-TAS8617204  
GO:0008285negative regulation of cell proliferation-IEA-  
GO:0009887animal organ morphogenesis-IEA-  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0016331morphogenesis of embryonic epithelium-IEA-  
GO:0030947regulation of vascular endothelial growth factor receptor signaling pathway-IEA-  
GO:0031954positive regulation of protein autophosphorylation-IEA-  
GO:0038084vascular endothelial growth factor signaling pathway-IBA21873635  
GO:0042493response to drug-IEA-  
GO:0043536positive regulation of blood vessel endothelial cell migration-IEA-  
GO:0045766positive regulation of angiogenesis-IBA21873635  
GO:0045776negative regulation of blood pressure-IEA-  
GO:0048010vascular endothelial growth factor receptor signaling pathway-IBA21873635  
GO:0048010vascular endothelial growth factor receptor signaling pathway-IDA23878260  
GO:0048010vascular endothelial growth factor receptor signaling pathway-TAS-  
GO:0050714positive regulation of protein secretion-IEA-  
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation-IEA-  
GO:0050918positive chemotaxis-IEA-  
GO:0050930induction of positive chemotaxis-IBA21873635  
GO:0050930induction of positive chemotaxis-IDA19275959  
GO:0051781positive regulation of cell division-IEA-  
GO:0060754positive regulation of mast cell chemotaxis-IBA21873635  
GO:0060754positive regulation of mast cell chemotaxis-IDA19275959  
GO:1901492positive regulation of lymphangiogenesis-IEA-  
GO:1990830cellular response to leukemia inhibitory factor-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IBA21873635  
GO:0016020membrane-IEA-  
GO:0031093platelet alpha granule lumen-TAS-  
KEGG ID KEGG Term
hsa04060Cytokine-cytokine receptor interaction
hsa04150mTOR signaling pathway
hsa04510Focal adhesion
hsa05200Pathways in cancer
hsa05211Renal cell carcinoma
hsa05212Pancreatic cancer
hsa05219Bladder cancer
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-114608Platelet degranulation TAS
R-HSA-162582Signal TransductionTAS
R-HSA-194138Signaling by VEGFTAS
R-HSA-194313VEGF ligand-receptor interactionsTAS
R-HSA-195399VEGF binds to VEGFR leading to receptor dimerizationTAS
R-HSA-76002Platelet activation, signaling and aggregationTAS
R-HSA-76005Response to elevated platelet cytosolic Ca2+TAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26072347Common Sequence Variation in the VEGFC Gene Is Associated with Diabetic Retinopathy and Diabetic Macular Edema. (2015 Sep)Kaidonis GOphthalmology