Gene: WEE1

7465
WEE1A|WEE1hu
WEE1 G2 checkpoint kinase
protein-coding
11p15.4
Ensembl:ENSG00000166483 MIM:193525 Vega:OTTHUMG00000165863 UniprotKB:P30291
NC_000011.10
PubMed
0   ANCO-SNPs
CD|ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.441e-1 (AD)  6.163e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
WWTR10.824
KDELC20.818
LATS20.801
CMTM60.797
MYL12A0.787
PRKD30.784
DRAM10.783
SLC43A30.781
PLP20.778
ELK30.773

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
BCL11A-0.618
CALHM1-0.602
LRTM2-0.597
KCNB2-0.591
SPRN-0.59
MYADML2-0.587
MARCH4-0.586
HAS1-0.582
ANKRD34A-0.576
CHRM1-0.575

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB046089-HYDROXY-4-PHENYL-6H-PYRROLO[3,4-C]CARBAZOLE-1,3-DIONESmall MoleculeExperimentalTarget
DB070069-HYDROXY-6-(3-HYDROXYPROPYL)-4-(2-METHOXYPHENYL)PYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONESmall MoleculeExperimentalTarget
DB07226N-[4-(2-CHLOROPHENYL)-1,3-DIOXO-1,2,3,6-TETRAHYDROPYRROLO[3,4-C]CARBAZOL-9-YL]FORMAMIDESmall MoleculeExperimentalTarget
DB072574-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2H,6H)-dioneSmall MoleculeExperimentalTarget
DB072653-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACIDSmall MoleculeExperimentalTarget
DB083658-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamideSmall MoleculeExperimentalTarget
DB11740MK-1775Small Molecule955365-80-7InvestigationalTarget
ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of WEE1 mRNA"26377693
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [Doxorubicin results in increased phosphorylation of WEE1 protein]"20826841
C0445652-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide results in decreased expression of WEE1 protein16142332
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of WEE1 mRNA"21346803
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of WEE1 mRNA]"19467301
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of WEE1 mRNA"18648102
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WEE1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WEE1 mRNA"27188386
C5538177-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one"7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one results in increased expression of WEE1 mRNA"19936915
D000082AcetaminophenAcetaminophen affects the expression of WEE1 mRNA25064622
D000082AcetaminophenAcetaminophen results in increased expression of WEE1 mRNA22230336
D000171AcroleinAcrolein results in increased expression of WEE1 mRNA26719373
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of WEE1 mRNA27153756
D000393Air PollutantsAir Pollutants analog results in decreased expression of WEE1 mRNA21757418
D000638AmiodaroneAmiodarone affects the expression of WEE1 mRNA25064622
D000643Ammonium ChlorideAmmonium Chloride affects the expression of WEE1 mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of WEE1 mRNA24449571
D000068180AripiprazoleAripiprazole results in increased expression of WEE1 mRNA17868501
C006632arsenic trioxidearsenic trioxide affects the expression of WEE1 mRNA18088464
C006632arsenic trioxidearsenic trioxide results in increased expression of and results in decreased phosphorylation of WEE1 protein22730174
C006632arsenic trioxidePTEN protein promotes the reaction [arsenic trioxide results in decreased phosphorylation of WEE1 protein]22730174
C006632arsenic trioxidearsenic trioxide results in increased expression of WEE1 protein23337567
D001280AtrazineAtrazine results in decreased expression of WEE1 mRNA22378314
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of WEE1 mRNA26377693
C030935benz(a)anthracene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of WEE1 mRNA27858113
D001554BenzeneBenzene results in increased expression of WEE115935813
D001554BenzeneBenzene results in increased expression of WEE1 mRNA12928149
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of WEE1 mRNA27858113
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of WEE1 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of WEE1 mRNA21632981
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of WEE1 mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of WEE1 mRNA20713471
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of WEE1 mRNA"20382639
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of WEE1 mRNA"20018196
C044887beta-methylcholinebeta-methylcholine affects the expression of WEE1 mRNA21179406
C006780bisphenol Abisphenol A affects the expression of WEE1 mRNA21786754
C006780bisphenol Abisphenol A results in decreased expression of WEE1 mRNA29275510
C006780bisphenol Abisphenol A results in decreased expression of WEE1 protein21277958
C006780bisphenol Abisphenol A affects the expression of WEE1 mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of WEE1 mRNA24988533
D000069286BortezomibBortezomib results in increased ubiquitination of WEE1 protein20367638
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of WEE1 mRNA15336504
D002104CadmiumCadmium results in decreased expression of WEE1 mRNA24376830
D019256Cadmium ChlorideCadmium Chloride results in increased expression of WEE1 mRNA18974090
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of WEE1 mRNA15056808
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of WEE1 mRNA12734012
C035377chlorendic acidchlorendic acid results in increased expression of WEE1 mRNA22584684
D002737ChloropreneChloroprene results in increased expression of WEE1 mRNA23125180
D002737ChloropreneChloroprene results in increased expression of WEE1 mRNA23125180
D002746ChlorpromazineChlorpromazine affects the expression of WEE1 mRNA25064622
C031180chrysene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of WEE1 mRNA27858113
D003033Coal TarCoal Tar results in decreased expression of WEE1 mRNA27858113
C018021cobaltous chloridecobaltous chloride results in increased expression of WEE1 mRNA24386269
D019327Copper SulfateCopper Sulfate results in increased expression of WEE1 mRNA19549813
C030123coumarincoumarin results in increased expression of WEE1 mRNA18480146
C057862cyanoginosin LRcyanoginosin LR results in increased expression of WEE1 mRNA17654400
D016572CyclosporineCyclosporine affects the expression of WEE1 mRNA25064622
D016572CyclosporineCyclosporine results in increased expression of WEE1 mRNA25562108
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of WEE1 mRNA23640034
D013759DronabinolDronabinol results in increased expression of WEE1 protein16818634
D003703DemecolcineDemecolcine results in decreased expression of WEE1 mRNA23649840
D003976DiazinonDiazinon results in increased methylation of WEE1 gene22964155
D003976DiazinonDiazinon affects the expression of WEE1 mRNA22546817
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of WEE1 mRNA28962523
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of WEE1 mRNA27392435
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of WEE1 mRNA26924002
D004026DieldrinDieldrin affects the expression of WEE1 mRNA22546817
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of WEE1 mRNA]"19467301
D004041Dietary FatsDietary Fats results in increased expression of WEE1 mRNA19467301
D004041Dietary Fats[Dietary Fats co-treated with resveratrol] results in decreased expression of WEE1 mRNA21852083
C024629dimethyl phthalatedimethyl phthalate affects the expression of WEE1 mRNA26924002
D004317Doxorubicin"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [Doxorubicin results in increased phosphorylation of WEE1 protein]"20826841
D004317DoxorubicinDoxorubicin results in increased phosphorylation of WEE1 protein20826841
D004317DoxorubicinDoxorubicin results in increased expression of WEE1 mRNA22712078
D004317DoxorubicinLovastatin inhibits the reaction [Doxorubicin results in increased expression of WEE1 mRNA]22712078
D004610Ellagic AcidEllagic Acid results in decreased expression of WEE1 protein23554011
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of WEE1 mRNA25064622
D005273FenbendazoleFenbendazole results in decreased expression of WEE1 protein modified form23411599
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of WEE1 mRNA22584684
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of WEE1 mRNA]15016801
C039281furanfuran results in increased expression of WEE1 mRNA22079235|2553966
C030691gluconic acidgluconic acid results in increased expression of WEE1 mRNA16556975
D006046Gold[Gold co-treated with Polyethylene Glycols] results in increased expression of WEE1 mRNA19695318
D017313FenretinideFenretinide results in increased expression of WEE1 mRNA28973697
D007213IndomethacinIndomethacin results in increased expression of WEE1 mRNA18299717
D007213Indomethacinrebamipide inhibits the reaction [Indomethacin results in increased expression of WEE1 mRNA]18299717
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of WEE1 mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of WEE1 mRNA27392435
C544151jinfukangjinfukang results in decreased expression of WEE1 mRNA27392435
C561695(+)-JQ1 compound[GNAQ gene mutant form results in increased susceptibility to (+)-JQ1 compound] which results in decreased expression of WEE1 protein26397223
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of WEE1 mRNA24796395
C410337K 7174K 7174 results in increased expression of WEE1 mRNA24086573
C045463leflunomideleflunomide results in increased expression of WEE1 mRNA28988120
D008148LovastatinLovastatin inhibits the reaction [Doxorubicin results in increased expression of WEE1 mRNA]22712078
D008148LovastatinLovastatin results in increased expression of WEE1 mRNA22712078
D008748MethylcholanthreneMethylcholanthrene promotes the reaction [AHR protein binds to WEE1 promoter]20348232
D008752Methylene ChlorideMethylene Chloride results in increased expression of WEE1 mRNA28392392
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of WEE1 mRNA26272509|2800136
C004925methylmercuric chloride"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WEE1 mRNA"27188386
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of WEE1 mRNA20061341
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of WEE1 mRNA26011545
D0156551-Methyl-4-phenylpyridiniumU 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of WEE1 mRNA]12710931
C549567MK-1775MK-1775 results in decreased phosphorylation of WEE1 protein25125259
C517284monomethyl phthalatemonomethyl phthalate affects the expression of WEE1 mRNA26924002
C008548morinmorin results in increased expression of WEE1 mRNA28689916
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of WEE1 mRNA"29244179
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of WEE1 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of WEE1 mRNA"25554681|2562005
C000621033napabucasinnapabucasin results in decreased expression of WEE1 mRNA25605917
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of WEE1 protein modified form23411599
C022838nickel chloridenickel chloride affects the expression of WEE1 mRNA22546817
C028007nickel monoxidenickel monoxide results in decreased expression of WEE1 mRNA19167457
D0151124-Nitroquinoline-1-oxide4-Nitroquinoline-1-oxide results in increased expression of WEE1 mRNA22561872
C025589ochratoxin Aochratoxin A results in increased expression of WEE1 mRNA23358140|2424370
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of WEE1 mRNA25729387
D010269ParaquatParaquat affects the expression of WEE1 mRNA25064622
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of WEE1 mRNA18593933
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid affects the expression of WEE1 mRNA19162173
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of WEE1 mRNA19162173
C539933pevonedistatpevonedistat results in increased abundance of WEE1 protein22110742
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of WEE1 mRNA]19482888
D010634PhenobarbitalPhenobarbital affects the expression of WEE1 mRNA23091169
D010634PhenobarbitalPhenobarbital results in increased expression of WEE1 mRNA19270015|1948288
D010634PhenobarbitalPhenobarbital results in decreased expression of WEE1 mRNA19162173
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of WEE1 mRNA19710929
C006253pirinixic acidpirinixic acid results in decreased expression of WEE1 protein19176532
C006253pirinixic acidpirinixic acid results in increased expression of WEE1 mRNA17426115
C006253pirinixic acidRXRA protein promotes the reaction [pirinixic acid results in decreased expression of WEE1 protein]19176532
C006253pirinixic acidpirinixic acid results in increased expression of WEE1 mRNA19162173
D011092Polyethylene Glycols[Gold co-treated with Polyethylene Glycols] results in increased expression of WEE1 mRNA19695318
D011137PolystyrenesPolystyrenes results in decreased expression of WEE1 mRNA25102311
D011441PropylthiouracilPropylthiouracil results in decreased expression of WEE1 mRNA24780913
D011794QuercetinQuercetin metabolite results in increased expression of WEE1 protein16280456
D011794QuercetinQuercetin results in decreased expression of WEE1 mRNA23727915
C052785rebamipiderebamipide inhibits the reaction [Indomethacin results in increased expression of WEE1 mRNA]18299717
C059514resveratrolresveratrol inhibits the reaction [temozolomide results in increased phosphorylation of WEE1 protein]23522185
C059514resveratrolresveratrol results in increased phosphorylation of WEE1 protein23522185
C059514resveratrol[Dietary Fats co-treated with resveratrol] results in decreased expression of WEE1 mRNA21852083
D012312RitodrineRitodrine results in increased expression of WEE1 mRNA23370008
D012822Silicon DioxideSilicon Dioxide results in decreased expression of WEE1 mRNA19073995
C017947sodium arsenitesodium arsenite results in decreased expression of WEE1 mRNA24176670
C017947sodium arsenitesodium arsenite results in increased expression of WEE1 mRNA11241755
C016104sodium bichromatesodium bichromate affects the expression of WEE1 mRNA22110744
D013311StreptozocinStreptozocin results in increased expression of WEE1 mRNA25905778
C061133tamibarotenetamibarotene affects the expression of WEE1 mRNA15498508
C047246temozolomideresveratrol inhibits the reaction [temozolomide results in increased phosphorylation of WEE1 protein]23522185
C047246temozolomidetemozolomide results in increased phosphorylation of WEE1 protein23522185
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of WEE1 mRNA21570461|2892240
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to WEE1 promoter]19654925
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of WEE1 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of WEE1 mRNA21215274
D013750TetrachloroethyleneTetrachloroethylene results in increased expression of WEE1 mRNA28973375
D013752TetracyclineTetracycline affects the expression of WEE1 mRNA25064622
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of WEE1 mRNA25613284
D019284ThapsigarginThapsigargin results in decreased expression of WEE1 mRNA22378314
D013853ThioacetamideThioacetamide affects the expression of WEE1 mRNA25064622
D013853ThioacetamideThioacetamide results in decreased expression of WEE1 protein modified form23411599
D013853ThioacetamideThioacetamide results in decreased phosphorylation of WEE1 protein22659510
D013853ThioacetamideThioacetamide results in increased expression of WEE1 mRNA22659510|2341159
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of WEE1 mRNA20133372
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of WEE1 mRNA28111298
D019772TopotecanWEE1 protein affects the susceptibility to Topotecan16217747
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of WEE1 mRNA25729387
D014212TretinoinTretinoin results in decreased expression of WEE1 mRNA15498508
C012589trichostatin Atrichostatin A affects the expression of WEE1 mRNA28542535
C057693troglitazonetroglitazone results in decreased expression of WEE1 mRNA19140230
D014415TunicamycinTunicamycin results in decreased expression of WEE1 mRNA22378314
C113580U 0126U 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of WEE1 mRNA]12710931
D014520Urethane[Urethane co-treated with IFNG protein] results in increased expression of WEE1 mRNA12810352
D014635Valproic AcidValproic Acid affects the expression of WEE1 mRNA25064622
D014635Valproic AcidValproic Acid affects the expression of WEE1 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of WEE1 mRNA28001369
D014635Valproic AcidValproic Acid results in increased methylation of WEE1 gene29154799
D014635Valproic AcidValproic Acid affects the expression of WEE1 mRNA17963808
C025643vinclozolinvinclozolin results in decreased expression of WEE1 mRNA15686871
D014750VincristineVincristine results in decreased expression of WEE1 mRNA23649840
C029297vinylidene chloridevinylidene chloride results in increased expression of WEE1 mRNA26682919
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of WEE1 mRNA18593933

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000287magnesium ion binding-IEA-  
GO:0004672protein kinase activity-IBA21873635  
GO:0004713protein tyrosine kinase activity-IBA21873635  
GO:0004713protein tyrosine kinase activity-TAS7774574  
GO:0004715non-membrane spanning protein tyrosine kinase activity-IEA-  
GO:0005515protein binding-IPI10775038  15070733  15161933  15324660  17353931  25241761  
GO:0005524ATP binding-IEA-  
GO:0016301kinase activity-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000082G1/S transition of mitotic cell cycle-TAS-  
GO:0000086G2/M transition of mitotic cell cycle-TAS-  
GO:0000226microtubule cytoskeleton organization-IEA-  
GO:0007093mitotic cell cycle checkpoint-IBA21873635  
GO:0018108peptidyl-tyrosine phosphorylation-IEA-  
GO:0030010establishment of cell polarity-IEA-  
GO:0048812neuron projection morphogenesis-IEA-  
GO:0051301cell division-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-TAS8348613  
GO:0005654nucleoplasm-TAS-  
GO:0005730nucleolus-IDA-  
GO:0005737cytoplasm-IEA-  
KEGG ID KEGG Term
hsa04110Cell cycle
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisIEA
R-HSA-156711Polo-like kinase mediated eventsTAS
R-HSA-1640170Cell CycleTAS
R-HSA-1640170Cell CycleIEA
R-HSA-453274Mitotic G2-G2/M phasesTAS
R-HSA-453274Mitotic G2-G2/M phasesIEA
R-HSA-453279Mitotic G1-G1/S phasesTAS
R-HSA-69202Cyclin E associated events during G1/S transition TAS
R-HSA-69206G1/S TransitionTAS
R-HSA-69242S PhaseTAS
R-HSA-69273Cyclin A/B1/B2 associated events during G2/M transitionTAS
R-HSA-69273Cyclin A/B1/B2 associated events during G2/M transitionIEA
R-HSA-69275G2/M TransitionTAS
R-HSA-69275G2/M TransitionIEA
R-HSA-69278Cell Cycle, MitoticTAS
R-HSA-69278Cell Cycle, MitoticIEA
R-HSA-69473G2/M DNA damage checkpointTAS
R-HSA-69473G2/M DNA damage checkpointIEA
R-HSA-69478G2/M DNA replication checkpointTAS
R-HSA-69481G2/M CheckpointsTAS
R-HSA-69481G2/M CheckpointsIEA
R-HSA-69620Cell Cycle CheckpointsTAS
R-HSA-69620Cell Cycle CheckpointsIEA
R-HSA-69656Cyclin A:Cdk2-associated events at S phase entryTAS
R-HSA-75035Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complexTAS
R-HSA-75035Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complexIEA
R-HSA-983231Factors involved in megakaryocyte development and platelet productionIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26719373Cytotoxicity of Thirdhand Smoke and Identification of Acrolein as a Volatile Thirdhand Smoke Chemical That Inhibits Cell Proliferation. (2016 Mar)Bahl VToxicol Sci