Gene: ZSCAN20

7579
KOX29|ZFP-31|ZNF31|ZNF360
zinc finger and SCAN domain containing 20
protein-coding
1p35.1
Ensembl:ENSG00000121903 MIM:611315 Vega:OTTHUMG00000004173 UniprotKB:P17040
NC_000001.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.386e-1 (AD)  1.369e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10798953chr1:33471534 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZNF700.789
GNL3L0.771
ZNF8080.752
MTF10.75
RNF1690.749
ZNF3970.743
CDK120.743
CEPT10.739
ZNF4170.739
ZNF3470.737

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PRSS27-0.308
C12orf54-0.262
SPDEF-0.255
CLDND2-0.243
OR4F29-0.24
OR4F5-0.238
CCT6B-0.234
LCN9-0.23
OR4F16-0.228
LCN1-0.224

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZSCAN20 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZSCAN20 mRNA"27188386
D000638AmiodaroneAmiodarone results in increased expression of ZSCAN20 mRNA19774075
D004958Estradiol[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZSCAN20 mRNA20823114
C006780bisphenol Abisphenol A affects the methylation of ZSCAN20 promoter27334623
C006780bisphenol Abisphenol A results in decreased methylation of ZSCAN20 promoter27312807
C030973cupric oxidecupric oxide results in increased expression of ZSCAN20 mRNA22077320
D003703DemecolcineDemecolcine results in increased expression of ZSCAN20 mRNA23649840
D003994Bucladesine[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZSCAN20 mRNA20823114
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ZSCAN20 mRNA25613284
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZSCAN20 mRNA20823114
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of ZSCAN20 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ZSCAN20 mRNA23649840
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in decreased expression of ZSCAN20 mRNA"29244179
C028007nickel monoxidenickel monoxide results in increased expression of ZSCAN20 mRNA19167457
C046012pentanalpentanal results in decreased expression of ZSCAN20 mRNA26079696
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ZSCAN20 mRNA24058054
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ZSCAN20 mRNA25613284
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of ZSCAN20 mRNA28065790
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZSCAN20 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of ZSCAN20 mRNA23179753|2627250
D014635Valproic AcidValproic Acid affects the expression of ZSCAN20 mRNA17963808
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of ZSCAN20 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding-IBA21873635  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-IBA21873635  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0003677DNA binding-IEA-  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IBA21873635  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO:0006367transcription initiation from RNA polymerase II promoter-IBA21873635  
GO:0006369termination of RNA polymerase II transcription-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal