Gene: ZNF37A

7587
KOX21|ZNF37
zinc finger protein 37A
protein-coding
10p11.1
Ensembl:ENSG00000075407 MIM:616085 Vega:OTTHUMG00000191777 UniprotKB:P17032
NC_000010.11
SNP Mapped
0   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.992e-1 (AD)  7.598e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
INTS70.874
TYW30.85
PDS5A0.848
UGGT10.845
ZC3H11A0.841
CDC42BPA0.836
NSD10.836
GNE0.832
ZBED40.832
RANBP20.83

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.497
OR4F29-0.478
ENDOU-0.374
TLCD1-0.311
PON3-0.287
ARHGAP8-0.283
HPDL-0.271
PON1-0.27
S100A14-0.266
HORMAD2-0.266

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C006632arsenic trioxidearsenic trioxide results in increased expression of ZNF37A mRNA15761015
D001241AspirinAspirin results in increased expression of ZNF37A mRNA11906190
C006780bisphenol Abisphenol A results in increased expression of ZNF37A mRNA25047013
D002110CaffeineCaffeine results in increased expression of ZNF37A mRNA18444173
D019327Copper SulfateCopper Sulfate results in increased expression of ZNF37A mRNA19549813
C030973cupric oxidecupric oxide results in increased expression of ZNF37A mRNA22077320
D016572CyclosporineCyclosporine results in increased expression of ZNF37A mRNA20106945
D002945CisplatinCisplatin results in decreased expression of ZNF37A mRNA27594783
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of ZNF37A mRNA22079256
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of ZNF37A mRNA23649840
D005557FormaldehydeFormaldehyde results in increased expression of ZNF37A mRNA23649840
D019833GenisteinGenistein results in decreased expression of ZNF37A mRNA18444173
C544151jinfukangjinfukang results in decreased expression of ZNF37A mRNA27392435
C410337K 7174K 7174 results in increased expression of ZNF37A mRNA24086573
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ZNF37A mRNA23649840
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in decreased expression of ZNF37A mRNA19095052
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of ZNF37A mRNA27153767
D010936Plant ExtractsPlant Extracts results in increased expression of ZNF37A mRNA23557933
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of ZNF37A mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of ZNF37A mRNA22079256
D017974Uranium CompoundsUranium Compounds results in increased expression of ZNF37A mRNA19654044
D014635Valproic AcidValproic Acid affects the expression of ZNF37A mRNA25979313

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0003677DNA binding-IEA-  
GO:0003700DNA-binding transcription factor activity-NAS8464732  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006355regulation of transcription, DNA-templated-NAS8464732  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA23922231  
GO:0005634nucleus-NAS8464732  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal