Gene: ZNF99

7652
C19orf9|F8281
zinc finger protein 99
protein-coding
19p12
Ensembl:ENSG00000213973 MIM:603981 Vega:OTTHUMG00000182992 UniprotKB:A8MXY4
NC_000019.10
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.549e-1 (AD)  1.824e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs6511383chr19:22774098 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4K30.728
DMRTC20.705
OR2M70.694
CD1B0.694
OR1I10.691
POU5F20.687
TAS2R410.686
OR10A70.683
OR2M50.68
OR9Q20.679

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ESPN-0.268
CCL27-0.227
PSPN-0.218
SSTR5-0.215
FOXD4L1-0.213
PRTN3-0.207
PLA2G5-0.205
DNAAF3-0.203
SIRT4-0.202
LRRC66-0.2

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of ZNF99 mRNA26690555
D019327Copper SulfateCopper Sulfate results in increased expression of ZNF99 mRNA19549813
D004726EndosulfanEndosulfan results in decreased expression of ZNF99 mRNA26615145

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0003677DNA binding-IEA-  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006355regulation of transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal