Gene: ZNF132

7691
pHZ-12
zinc finger protein 132
protein-coding
19q13.43
Ensembl:ENSG00000131849 MIM:604074 Vega:OTTHUMG00000183537 UniprotKB:P52740
NC_000019.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.468e-1 (AD)  6.168e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZNF3980.885
HIF1AN0.882
DNAJC110.869
TUBGCP40.867
CHAMP10.864
RALGAPB0.863
SBNO10.861
POLR3B0.86
MTOR0.857
COG80.856

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MYL3-0.418
OR4F5-0.415
ROM1-0.41
KLRC3-0.403
RAB13-0.4
CSAG1-0.382
KLRC2-0.37
IL18RAP-0.37
SNHG18-0.369
FAM89A-0.363

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C015001arsenitearsenite results in increased methylation of ZNF132 promoter23974009
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ZNF132 mRNA22316170
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of ZNF132 mRNA23649840
D004397FonofosFonofos results in increased methylation of ZNF132 promoter22847954
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ZNF132 mRNA23649840
D010278ParathionParathion results in increased methylation of ZNF132 promoter22847954
D012822Silicon DioxideSilicon Dioxide results in decreased expression of ZNF132 mRNA25351596
C012568terbufosterbufos results in increased methylation of ZNF132 promoter22847954
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ZNF132 mRNA22574217
D014520UrethaneUrethane results in decreased expression of ZNF132 mRNA28818685
D014638VanadatesVanadates results in increased expression of ZNF132 mRNA22714537

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0003677DNA binding-IEA-  
GO:0003700DNA-binding transcription factor activity-TAS7557990  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24268366Comparison of genome-wide DNA methylation in urothelial carcinomas of patients with and without arsenic exposure. (2014 Jan)Yang TYEnviron Res