Gene: ZNF133

7692
ZNF150|pHZ-13|pHZ-66
zinc finger protein 133
protein-coding
20p11.23
Ensembl:ENSG00000125846 MIM:604075 Vega:OTTHUMG00000031965 UniprotKB:P52736
NC_000020.11
PubMed
0   ANCO-SNPs
AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.466e-1 (AD)  6.275e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DMAP10.924
HKR10.924
CENPT0.916
AP4B10.911
DDX510.907
POMT10.9
CERS50.9
ABCC100.897
AGAP60.895
RABL2A0.891

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.517
OR4F29-0.483
MTRNR2L9-0.325
MTRNR2L6-0.309
TFPI2-0.297
MTRNR2L10-0.296
TRDN-0.295
ARHGAP42-0.285
LRAT-0.284
PHEX-0.281

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of ZNF133 mRNA"19095052
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of ZNF133 gene27153756
D001151ArsenicArsenic affects the methylation of ZNF133 gene25304211
C015001arsenitearsenite results in increased methylation of ZNF133 promoter23974009
C044887beta-methylcholinebeta-methylcholine affects the expression of ZNF133 mRNA21179406
D019327Copper SulfateCopper Sulfate results in decreased expression of ZNF133 mRNA19549813
D016572CyclosporineCyclosporine results in increased expression of ZNF133 mRNA25562108
C000944dicrotophosdicrotophos results in decreased expression of ZNF133 mRNA28302478
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of ZNF133 mRNA20044591
C045463leflunomideleflunomide results in increased expression of ZNF133 mRNA28988120
C029938nickel sulfatenickel sulfate results in decreased expression of ZNF133 mRNA22714537
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in increased expression of ZNF133 mRNA19095052
D010634PhenobarbitalPhenobarbital affects the expression of ZNF133 mRNA19159669
C017947sodium arsenitesodium arsenite results in decreased expression of ZNF133 mRNA22714537
D014520UrethaneUrethane results in decreased expression of ZNF133 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of ZNF133 mRNA25979313
D024483Vitamin K 3Vitamin K 3 affects the expression of ZNF133 mRNA20044591

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0003677DNA binding-IEA-  
GO:0003700DNA-binding transcription factor activity-IBA21873635  
GO:0003700DNA-binding transcription factor activity-TAS7557990  9278146  
GO:0005515protein binding-IPI20195357  25416956  
GO:0043565sequence-specific DNA binding-IBA21873635  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
14578011Human alcoholism studies of genes identified through mouse quantitative trait locus analysis. (2002 Oct)Ehringer MAAddict Biol