Gene: ZNF184

7738
kr-ZNF3
zinc finger protein 184
protein-coding
6p22.1
Ensembl:ENSG00000096654 MIM:602277 Vega:OTTHUMG00000014478 UniprotKB:Q99676
NG_052614.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.460e-1 (AD)  7.203e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TIAM20.9
CACNB20.9
FAM84A0.897
FBXO340.886
NEDD4L0.875
GPR220.874
ARHGEF30.873
CNST0.871
LRRTM40.87
PDP10.87

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MYL3-0.481
HEY2-0.463
FZD10-0.457
CTNNA3-0.451
SNHG18-0.45
PSTPIP1-0.442
CSAG1-0.441
MBNL3-0.43
SH2D1A-0.429
RAI14-0.425

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C547126AZM551248AZM551248 results in decreased expression of ZNF184 mRNA22323515
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZNF184 mRNA"20382639
D019327Copper SulfateCopper Sulfate results in decreased expression of ZNF184 mRNA19549813
D016572CyclosporineCyclosporine results in increased expression of ZNF184 mRNA20106945|2556210
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of ZNF184 mRNA23649840
D005557FormaldehydeFormaldehyde results in decreased expression of ZNF184 mRNA20655997
C045463leflunomideleflunomide results in increased expression of ZNF184 mRNA28988120
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ZNF184 mRNA23649840
C029938nickel sulfatenickel sulfate results in increased expression of ZNF184 mRNA22714537
D011794QuercetinQuercetin results in decreased expression of ZNF184 mRNA21632981
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ZNF184 mRNA22574217
D014520UrethaneUrethane results in increased expression of ZNF184 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of ZNF184 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased methylation of ZNF184 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of ZNF184 mRNA29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0003677DNA binding-IEA-  
GO:0008270zinc ion binding-NAS9073517  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27565901Pleiotropic Analysis of Lung Cancer and Blood Triglycerides. (2016 Dec)Zuber VJ Natl Cancer Inst