Gene: PTP4A1

7803
HH72|PRL-1|PRL1|PTP(CAAX1)|PTPCAAX1
protein tyrosine phosphatase type IVA, member 1
protein-coding
6q12
Ensembl:ENSG00000112245 MIM:601585 Vega:OTTHUMG00000014949 UniprotKB:Q93096
NC_000006.12
PubMed
0   ANCO-SNPs
AD
5   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.072e-1 (AD)  5.665e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ETF10.89
FYTTD10.889
STX120.88
GTPBP40.874
ACBD30.874
VAMP70.867
ACTR30.866
HAUS20.864
HNRNPR0.864
CHMP2B0.864

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.598
OR4F29-0.596
GLI1-0.291
NXNL1-0.251
KCNJ16-0.242
MTRNR2L10-0.227
DIAPH3-0.22
HIGD1B-0.217
P2RY14-0.208
NWD1-0.208

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of PTP4A1 mRNA"26377693
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of PTP4A1 mRNA"19162173
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of PTP4A1 mRNA"28903501
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of PTP4A1 mRNA"19095052
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PTP4A1 mRNA"19167446
C0194992-nitrofluorene2-nitrofluorene results in increased expression of PTP4A1 mRNA15890375
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of PTP4A1 mRNA]"19467301
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of PTP4A1 mRNA"18648102
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PTP4A1 mRNA15890375
D000082AcetaminophenAcetaminophen results in decreased expression of PTP4A1 mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of PTP4A1 mRNA17562736
D020106AcrylamideAcrylamide results in increased expression of PTP4A1 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of PTP4A1 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of PTP4A1 mRNA15890375
D000452AldrinAldrin results in decreased expression of PTP4A1 mRNA18579281
D000643Ammonium ChlorideAmmonium Chloride affects the expression of PTP4A1 mRNA16483693
D016718Arachidonic AcidArachidonic Acid results in increased expression of PTP4A1 mRNA16704987
D001151ArsenicArsenic affects the methylation of PTP4A1 gene25304211
D001241AspirinAspirin results in increased expression of PTP4A1 mRNA14976132
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of PTP4A1 mRNA20064835
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of PTP4A1 mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of PTP4A1 mRNA21569818
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PTP4A1 mRNA"19150397
D004958EstradiolCycloheximide inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]]19146866
D004958EstradiolCycloheximide promotes the reaction [Estradiol results in increased expression of PTP4A1 mRNA]19146866
D004958EstradiolDexamethasone inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]19146866
D004958EstradiolEstradiol affects the expression of PTP4A1 mRNA22574217
D004958EstradiolEstradiol results in increased expression of PTP4A1 mRNA19146866
D004958EstradiolMedroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]19146866
C543008bis(4-hydroxyphenyl)sulfone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of PTP4A1 mRNA28628672
C006780bisphenol Abisphenol A affects the expression of PTP4A1 mRNA21786754
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PTP4A1 mRNA28628672
C006780bisphenol Abisphenol A results in decreased expression of PTP4A1 mRNA26063408
C006780bisphenol Abisphenol A results in increased expression of PTP4A1 mRNA25594700
C006780bisphenol Abisphenol A results in increased expression of PTP4A1 mRNA25181051
C013418bromfenacoumbromfenacoum results in increased expression of PTP4A1 protein28903499
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PTP4A1 mRNA22079614
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of PTP4A1 mRNA15336504
C018475butyraldehydebutyraldehyde results in decreased expression of PTP4A1 mRNA26079696
D002087ButyratesButyrates results in decreased expression of PTP4A1 mRNA14674679
D019256Cadmium Chloride[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of PTP4A1 mRNA12634122
C459604candoxincandoxin results in decreased expression of PTP4A1 mRNA16309724
D002220CarbamazepineCarbamazepine affects the expression of PTP4A1 mRNA25979313
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of PTP4A1 mRNA24763279
D002737ChloropreneChloroprene results in increased expression of PTP4A1 mRNA23125180
C023600chromic oxide[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of PTP4A1 mRNA12634122
C017133chromous chloride[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of PTP4A1 mRNA12634122
D002922CiguatoxinsCiguatoxins affects the expression of PTP4A1 mRNA18353800
D002994ClofibrateClofibrate affects the expression of PTP4A1 mRNA16081524
C018021cobaltous chloridecobaltous chloride results in decreased expression of PTP4A1 mRNA21139344
D003078ColchicineColchicine results in decreased expression of PTP4A1 mRNA24211769
D019327Copper SulfateCopper Sulfate results in decreased expression of PTP4A1 mRNA18579281
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PTP4A1 mRNA"19167446
D003375CoumestrolCoumestrol results in increased expression of PTP4A1 mRNA19167446
D003513CycloheximideCycloheximide inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]]19146866
D003513CycloheximideCycloheximide promotes the reaction [Estradiol results in increased expression of PTP4A1 mRNA]19146866
D003520CyclophosphamideCyclophosphamide results in increased expression of PTP4A1 mRNA15331540
D003703DemecolcineDemecolcine results in increased expression of PTP4A1 mRNA23649840
D003907DexamethasoneDexamethasone inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]19146866
D003907DexamethasoneDexamethasone results in decreased expression of PTP4A1 mRNA25047013
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of PTP4A1 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PTP4A1 mRNA28628672
D003907Dexamethasone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA16054899
D003907Dexamethasone[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA]16054899
D003907DexamethasoneTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA]16054899
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of PTP4A1 mRNA17361019|2126653
D002945CisplatinCisplatin results in decreased expression of PTP4A1 mRNA24211769|2759478
D002945Cisplatin[Piroxicam co-treated with Cisplatin] results in decreased expression of PTP4A1 mRNA21858171
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of PTP4A1 mRNA]"19467301
D004041Dietary FatsDietary Fats results in increased expression of PTP4A1 mRNA19030233|1946730
D004041Dietary Fatsrimonabant inhibits the reaction [Dietary Fats results in increased expression of PTP4A1 mRNA]19030233
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of PTP4A1 mRNA15890375
D002117CalcitriolCalcitriol results in increased expression of PTP4A1 mRNA16002434
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of PTP4A1 mRNA15890375
D004317DoxorubicinDoxorubicin results in increased expression of PTP4A1 mRNA25896364
D004785Environmental PollutantsEnvironmental Pollutants results in decreased expression of PTP4A1 mRNA12655031
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PTP4A1 mRNA22079256
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of PTP4A1 mRNA23649840
C082360fipronilfipronil results in increased expression of PTP4A1 mRNA23962444
D005485FlutamideFlutamide results in decreased expression of PTP4A1 mRNA24136188
D005557FormaldehydeFormaldehyde results in increased expression of PTP4A1 mRNA23649840
C069837fullerene C60fullerene C60 results in decreased expression of PTP4A1 mRNA19167457
C056933fumonisin B1fumonisin B1 results in increased expression of PTP4A1 mRNA16221962
C039281furanfuran results in increased expression of PTP4A1 mRNA26194646
C039281furanfuran results in increased methylation of PTP4A1 gene22079235
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of PTP4A1 mRNA24763279
D017313FenretinideFenretinide results in decreased expression of PTP4A1 mRNA28973697
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of PTP4A1 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PTP4A1 mRNA28628672
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PTP4A1 mRNA25613284
C051890irinotecanirinotecan analog results in decreased expression of PTP4A1 mRNA18927307
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of PTP4A1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PTP4A1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA16054899
D0150561-Methyl-3-isobutylxanthine[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA]16054899
D0150561-Methyl-3-isobutylxanthineTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA]16054899
D007545IsoproterenolIsoproterenol results in increased expression of PTP4A1 mRNA20003209
C544151jinfukangjinfukang results in decreased expression of PTP4A1 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of PTP4A1 mRNA23086925
C008261lead acetate[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of PTP4A1 mRNA12634122
C008261lead acetatelead acetate results in decreased expression of PTP4A1 mRNA21829687
C045463leflunomideleflunomide results in increased expression of PTP4A1 mRNA28988120
D001556LindaneLindane results in increased expression of PTP4A1 mRNA17785943
C482199lipopolysaccharide, E coli O55-B5"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PTP4A1 mRNA"18930950
D017258Medroxyprogesterone AcetateCycloheximide inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]]19146866
D017258Medroxyprogesterone AcetateMedroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]19146866
D008627Mercuric ChlorideMercuric Chloride results in increased expression of PTP4A1 mRNA16507785
D008701MethapyrileneMethapyrilene results in increased expression of PTP4A1 mRNA15890375
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of PTP4A1 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of PTP4A1 mRNA26011545
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of PTP4A1 mRNA23649840
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased expression of PTP4A1 mRNA12634122
D008777MethyltestosteroneMethyltestosterone results in increased expression of PTP4A1 mRNA29191790
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of PTP4A1 mRNA"29244179
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of PTP4A1 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of PTP4A1 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of PTP4A1 mRNA"25554681
D009532NickelNickel results in increased expression of PTP4A1 mRNA24768652|2558310
C028007nickel monoxidenickel monoxide affects the expression of PTP4A1 mRNA19167457
C012655nimesulidenimesulide results in increased expression of PTP4A1 mRNA24136188
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of PTP4A1 mRNA17616710
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PTP4A1 mRNA"12756304
D010081OxazoloneOxazolone results in increased expression of PTP4A1 mRNA23999411
D010098OxycodoneOxycodone results in increased expression of PTP4A1 mRNA23439660
D010126OzoneOzone results in increased expression of PTP4A1 mRNA21543283
C016030pantogabpantogab results in increased expression of PTP4A1 mRNA17379144
D052638Particulate MatterParticulate Matter results in decreased expression of PTP4A1 mRNA22178795
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in increased expression of PTP4A1 mRNA19095052
D010426Pentosan Sulfuric PolyesterPentosan Sulfuric Polyester results in increased expression of PTP4A1 mRNA28973697
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of PTP4A1 mRNA19162173
D010575PesticidesPesticides results in decreased methylation of PTP4A1 gene28396702
D010634PhenobarbitalPhenobarbital results in increased expression of PTP4A1 mRNA19270015
D010634PhenobarbitalPhenobarbital results in increased expression of PTP4A1 mRNA12807726|1916217
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of PTP4A1 mRNA15890375
C006253pirinixic acidpirinixic acid results in increased expression of PTP4A1 mRNA16221962|1844570
C006253pirinixic acidpirinixic acid results in increased expression of PTP4A1 mRNA15890375
D010894Piroxicam[Piroxicam co-treated with Cisplatin] results in decreased expression of PTP4A1 mRNA21858171
D010938Plant OilsPlant Oils results in increased expression of PTP4A1 mRNA23370395
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PTP4A1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of PTP4A1 mRNA22079256
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of PTP4A1 mRNA28903501
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of PTP4A1 mRNA19162173
C045950propiconazolepropiconazole results in increased expression of PTP4A1 mRNA19363144|2127805
D011441PropylthiouracilPropylthiouracil results in increased expression of PTP4A1 mRNA24780913
C089032rimonabantrimonabant inhibits the reaction [Dietary Fats results in increased expression of PTP4A1 mRNA]19030233
C089730rosiglitazone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA16054899
C089730rosiglitazone[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA]16054899
C089730rosiglitazoneTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA]16054899
C009250sevofluranesevoflurane affects the expression of PTP4A1 mRNA15967596
D012822Silicon DioxideSilicon Dioxide results in increased expression of PTP4A1 mRNA23221170
D012834SilverSilver results in decreased expression of PTP4A1 mRNA27131904
D012906SmokeSmoke results in decreased expression of PTP4A1 mRNA21095227
C009277sodium arsenatesodium arsenate results in increased expression of PTP4A1 mRNA23922661
C017947sodium arsenite[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of PTP4A1 mRNA12634122
C017947sodium arsenitesodium arsenite results in increased expression of PTP4A1 mRNA12760830
D053260SootSoot results in increased expression of PTP4A1 mRNA22461453|2655175
D0150852,4,5-Trichlorophenoxyacetic Acid"2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PTP4A1 mRNA"18579281
D013629TamoxifenTamoxifen affects the expression of PTP4A1 mRNA20937368
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of PTP4A1 mRNA28922406
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA]16054899
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with EGF protein] results in decreased expression of PTP4A1 mRNA16054899
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PTP4A1 mRNA]16054899
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of PTP4A1 mRNA16054899
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of PTP4A1 mRNA19770486
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of PTP4A1 mRNA22298810
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PTP4A1 mRNA25613284
D013806TheophyllineTheophylline results in decreased expression of PTP4A1 mRNA16083514
C483909torcetrapibtorcetrapib results in increased expression of PTP4A1 mRNA23228038
C034613triacsin Ctriacsin C results in increased expression of PTP4A1 mRNA16704987
D014241TrichloroethyleneTrichloroethylene results in increased expression of PTP4A1 mRNA19448997
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of PTP4A1 mRNA"26179874
C080163trovafloxacin"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PTP4A1 mRNA"18930950
C080163trovafloxacintrovafloxacin results in increased expression of PTP4A1 mRNA24136188
D014635Valproic AcidValproic Acid affects the expression of PTP4A1 mRNA25979313
D014635Valproic AcidValproic Acid results in increased methylation of PTP4A1 gene29154799
D014635Valproic AcidValproic Acid affects the expression of PTP4A1 mRNA17292431|1796380
D014635Valproic AcidValproic Acid results in decreased expression of PTP4A1 mRNA20546886
D014752Vinyl ChlorideVinyl Chloride results in decreased expression of PTP4A1 mRNA18579281
D000225AdenineAdenine results in decreased expression of PTP4A1 mRNA24211769
D014810Vitamin EVitamin E results in decreased expression of PTP4A1 mRNA19244175

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004725protein tyrosine phosphatase activity-IBA21873635  
GO:0004725protein tyrosine phosphatase activity-NAS10569806  
GO:0005515protein binding-IPI17353931  28330616  
GO:0008138protein tyrosine/serine/threonine phosphatase activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0007049cell cycle-IEA-  
GO:0007275multicellular organism development-IEA-  
GO:0030335positive regulation of cell migration-IBA21873635  
GO:0035335peptidyl-tyrosine dephosphorylation-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005737cytoplasm-IBA21873635  
GO:0005737cytoplasm-IDA10940933  
GO:0005769early endosome-IEA-  
GO:0005783endoplasmic reticulum-IEA-  
GO:0005819spindle-IEA-  
GO:0009898cytoplasmic side of plasma membrane-IDA10940933  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
25991709Identification of candidate genes that underlie the QTL on chromosome 1 that mediates genetic differences in stress-ethanol interactions. (2015 Aug)Cook MNPhysiol Genomics
24961364Common PTP4A1-PHF3-EYS variants are specific for alcohol dependence. (2014 Jul-Aug)Zuo LAm J Addict
22096494A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. (2011)Zuo LPLoS One
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