Gene: MALL

7851
BENE
mal, T cell differentiation protein like
protein-coding
2q13
Ensembl:ENSG00000144063 MIM:602022 Vega:OTTHUMG00000131196 UniprotKB:Q13021
NC_000002.12
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.088e-1 (AD)  6.332e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CARD60.747
VEGFC0.743
SVIL0.742
NPR10.734
TES0.731
SULT1B10.73
FBLIM10.729
MMRN20.729
HSPG20.725
TNFAIP80.721

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ASPDH-0.385
HAGHL-0.355
BAIAP2L2-0.35
RS1-0.342
FBLL1-0.341
HES6-0.339
C19orf73-0.333
KCNIP3-0.332
BCL11A-0.327
SLC25A10-0.327

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C016601afimoxifeneafimoxifene results in decreased expression of MALL mRNA19901195
C016601afimoxifeneafimoxifene results in increased expression of MALL mRNA19698761
C006632arsenic trioxideMALL protein results in decreased susceptibility to arsenic trioxide20707922
C015001arsenitearsenite results in decreased methylation of MALL promoter23974009
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of MALL mRNA19619570
D004958EstradiolEstradiol results in increased expression of MALL mRNA19619570|1969876
C006780bisphenol Abisphenol A results in decreased methylation of MALL gene22576693
C006780bisphenol Abisphenol A results in increased expression of MALL mRNA22576693
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MALL mRNA28628672
C006780bisphenol Abisphenol A results in decreased expression of MALL mRNA25181051
C018475butyraldehydebutyraldehyde results in decreased expression of MALL mRNA26079696
D002104CadmiumCadmium results in increased expression of MALL mRNA21120746
C018021cobaltous chloridecobaltous chloride results in decreased expression of MALL mRNA19320972|1937684
D003471CuprizoneCuprizone results in decreased expression of MALL mRNA27523638
D003471CuprizoneCuprizone results in increased expression of MALL mRNA26577399
D000069439DasatinibDasatinib results in decreased expression of MALL mRNA20579391
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MALL mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of MALL mRNA28628672
D004041Dietary FatsDietary Fats results in increased expression of MALL mRNA25016146
D002117CalcitriolCalcitriol results in increased expression of MALL mRNA16002434
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of MALL mRNA17557909
D005492Folic AcidFolic Acid affects the expression of MALL mRNA17320366
D004397FonofosFonofos results in increased methylation of MALL promoter22847954
C039281furanfuran results in increased expression of MALL mRNA27387713
C004312glycidolglycidol results in increased expression of MALL mRNA24915197
C016517indole-3-carbinolindole-3-carbinol affects the expression of MALL mRNA21396975
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MALL mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of MALL mRNA28628672
C051890irinotecanirinotecan metabolite results in increased expression of MALL mRNA15956246
C051890irinotecanirinotecan results in increased expression of MALL mRNA15956246
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MALL mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of MALL mRNA28628672
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of MALL mRNA26752646
D008345ManganeseManganese results in decreased expression of MALL mRNA26745496
C025340manganese chloridemanganese chloride results in decreased expression of MALL mRNA26745496
C500085muraglitazarmuraglitazar results in increased expression of MALL mRNA21515302
D010100OxygenOxygen deficiency results in decreased expression of MALL mRNA26516004
D010278ParathionParathion results in increased methylation of MALL promoter22847954
C006253pirinixic acidpirinixic acid results in decreased expression of MALL mRNA17426115
D010936Plant ExtractsPlant Extracts results in decreased expression of MALL mRNA23557933
D010938Plant OilsPlant Oils results in decreased expression of MALL mRNA23370395
D011441PropylthiouracilPropylthiouracil results in increased expression of MALL mRNA24780913
D012643SeleniumSelenium results in increased expression of MALL mRNA19244175
C078903seocalcitolseocalcitol results in increased expression of MALL mRNA12040012
D012999SomanSoman results in increased expression of MALL mRNA19281266
C012568terbufosterbufos results in increased methylation of MALL promoter22847954
C501413tesaglitazartesaglitazar results in increased expression of MALL mRNA21515302
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of MALL mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of MALL mRNA19619570|1990119
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of MALL mRNA21354282
C009495titanium dioxidetitanium dioxide results in decreased expression of MALL mRNA23557971
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of MALL mRNA19042947
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of MALL mRNA"26179874
D001335Vehicle EmissionsVehicle Emissions affects the methylation of MALL gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI11294831  25416956  
GO:0019911structural constituent of myelin sheath-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0042552myelination-IBA21873635  
GO:0042632cholesterol homeostasis-NAS11294831  
GO ID GO Term Qualifier Evidence PubMed
GO:0000139Golgi membrane-IDA11294831  
GO:0005886plasma membrane-IDA11294831  
GO:0016021integral component of membrane-IBA21873635  
GO:0030136clathrin-coated vesicle-IDA11294831  
GO:0031410cytoplasmic vesicle-IDA11294831  
GO:0045121membrane raft-IDA11294831  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
11419600Indoor air quality at nine shopping malls in Hong Kong. (2001 Jun 12)Li WMSci Total Environ