Gene: SNIP1

79753
PML1|PMRED
Smad nuclear interacting protein 1
protein-coding
1p34.3
Ensembl:ENSG00000163877 MIM:608241 Vega:OTTHUMG00000004225 UniprotKB:Q8TAD8
NG_032170.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.458e-2 (AD)  1.207e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FAF20.904
PDE120.903
RNF40.902
RPRD1B0.9
ANKLE20.9
PSMD50.894
FOXJ30.894
PRPF40.893
YME1L10.889
YRDC0.889

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.546
OR4F29-0.491
CTNNA3-0.284
OR4F16-0.282
TNFRSF13B-0.282
MTRNR2L9-0.282
MTRNR2L6-0.274
SH2D1A-0.273
KLRK1-0.272
C5orf64-0.266

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C517041(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)"(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) results in increased expression of SNIP1 mRNA"19561079
D000082AcetaminophenAcetaminophen affects the expression of SNIP1 mRNA17562736
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of SNIP1 mRNA24449571
D001104ArbutinArbutin results in decreased expression of SNIP1 mRNA17103032
D001151ArsenicArsenic affects the methylation of SNIP1 gene25304211
D001280AtrazineAtrazine results in decreased expression of SNIP1 mRNA22378314
C006780bisphenol Abisphenol A affects the expression of SNIP1 mRNA21786754
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SNIP1 mRNA28628672
C006780bisphenol Abisphenol A affects the methylation of SNIP1 promoter27415467
C006780bisphenol Abisphenol A results in increased expression of SNIP1 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of SNIP1 gene28505145
C018021cobaltous chloridecobaltous chloride results in increased expression of SNIP1 mRNA19320972
D003300Copper[Disulfiram binds to Copper] which results in decreased expression of SNIP1 mRNA24690739
D019327Copper SulfateCopper Sulfate results in increased expression of SNIP1 mRNA19549813
C030973cupric oxidecupric oxide results in increased expression of SNIP1 mRNA22077320
C007262deoxynivalenoldeoxynivalenol affects the phosphorylation of SNIP1 protein23352502
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SNIP1 mRNA28628672
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of SNIP1 mRNA28085963
D004221Disulfiram[Disulfiram binds to Copper] which results in decreased expression of SNIP1 mRNA24690739
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SNIP1 mRNA22079256
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SNIP1 mRNA28628672
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SNIP1 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SNIP1 mRNA28628672
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of SNIP1 mRNA23649840
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of SNIP1 mRNA18593933
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SNIP1 mRNA19710929
D010938Plant OilsPlant Oils results in increased expression of SNIP1 mRNA23370395
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SNIP1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of SNIP1 mRNA22079256
C009131pyrimidin-2-one beta-ribofuranosidepyrimidin-2-one beta-ribofuranoside results in decreased expression of SNIP1 mRNA19194470
D012834SilverSilver results in increased expression of SNIP1 mRNA26014281
C017947sodium arsenitesodium arsenite affects the expression of SNIP1 mRNA29319823
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SNIP1 mRNA21570461
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SNIP1 mRNA25613284
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of SNIP1 mRNA28065790
D014415TunicamycinTunicamycin results in increased expression of SNIP1 mRNA17127020
D014520UrethaneUrethane results in increased expression of SNIP1 mRNA28818685
D014635Valproic AcidValproic Acid results in decreased expression of SNIP1 mRNA26272509
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of SNIP1 gene25560391
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of SNIP1 mRNA18593933

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-HDA22658674  
GO:0003729mRNA binding-IBA21873635  
GO:0005515protein binding-IPI17157259  18794151  21516116  22365833  25416956  
GO ID GO Term Qualifier Evidence PubMed
GO:0006355regulation of transcription, DNA-templated-IEA-  
GO:0007249I-kappaB kinase/NF-kappaB signaling-IEA-  
GO:0035196production of miRNAs involved in gene silencing by miRNA-IBA21873635  
GO:0035196production of miRNAs involved in gene silencing by miRNA-IMP18632581  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005654nucleoplasm-IDA-  
GO:0005829cytosol-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29634978Clinical implication of programmed death-ligand 1 expression in tonsillar squamous cell carcinoma in association with intratumoral heterogeneity, human papillomavirus, and epithelial-to-mesenchymal transition. (2018 Apr 7)Kwon MJHum Pathol