Gene: SUGCT

79783
C7orf10|DERP13|GA3|ORF19
succinyl-CoA:glutarate-CoA transferase
protein-coding
7p14.1
Ensembl:ENSG00000175600 MIM:609187 Vega:OTTHUMG00000155094 UniprotKB:Q9HAC7
NG_023422.1
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.047e-1 (AD)  3.456e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs17620991chr7:40796922 (GRCh38.p7)G>C / G>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0122771,2-diamino-4-nitrobenzene"1,2-diamino-4-nitrobenzene results in increased expression of SUGCT mRNA"17070881
C0353141-nitropropane1-nitropropane results in decreased expression of SUGCT mRNA17070881
C0109142,4-diaminotoluene"2,4-diaminotoluene results in decreased expression of SUGCT mRNA"17070881
C0252352,6-diaminotoluene"2,6-diaminotoluene results in decreased expression of SUGCT mRNA"17070881
C0147062-nitro-4-phenylenediamine2-nitro-4-phenylenediamine results in increased expression of SUGCT mRNA17070881
C0166172-nitropropane2-nitropropane results in decreased expression of SUGCT mRNA17070881
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SUGCT mRNA"23196670
C0286764-acetylaminofluorene4-acetylaminofluorene results in increased expression of SUGCT mRNA17070881
D000082AcetaminophenAcetaminophen results in decreased expression of SUGCT mRNA29067470
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of SUGCT mRNA22100608
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of SUGCT mRNA24449571
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of SUGCT mRNA20106945|2163298
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SUGCT mRNA"26238291
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of SUGCT mRNA"20382639
C006780bisphenol A[bisphenol A co-treated with Genistein] results in decreased methylation of SUGCT gene28505145
C006780bisphenol Abisphenol A results in decreased expression of SUGCT mRNA25181051
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of SUGCT mRNA27339419
C100187chloropicrinchloropicrin results in decreased expression of SUGCT mRNA26352163
D002994ClofibrateClofibrate results in increased expression of SUGCT mRNA23811191
D019327Copper SulfateCopper Sulfate results in decreased expression of SUGCT mRNA19549813
D016572CyclosporineCyclosporine results in decreased expression of SUGCT mRNA20106945|2556210
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of SUGCT mRNA27392435
D002945CisplatinCisplatin results in increased expression of SUGCT mRNA27392435
D002945CisplatinCisplatin results in decreased expression of SUGCT mRNA22023808
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of SUGCT mRNA24535843
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of SUGCT mRNA"23811387
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of SUGCT mRNA23649840
D018120FinasterideFinasteride results in increased expression of SUGCT mRNA24136188
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in decreased expression of SUGCT mRNA17070881
D005485FlutamideFlutamide results in decreased expression of SUGCT mRNA24793618
D005557FormaldehydeFormaldehyde results in increased expression of SUGCT mRNA23649840
C039281furanfuran results in decreased expression of SUGCT mRNA26194646
D019833Genistein[bisphenol A co-treated with Genistein] results in decreased methylation of SUGCT gene28505145
D017313FenretinideFenretinide results in increased expression of SUGCT mRNA28973697
C016517indole-3-carbinolindole-3-carbinol affects the expression of SUGCT mRNA21396975
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of SUGCT mRNA27392435
D007854LeadLead results in decreased expression of SUGCT mRNA19921347
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of SUGCT mRNA23649840
D009151Mustard GasMustard Gas results in increased expression of SUGCT mRNA25102026
D009285NaphthoquinonesNaphthoquinones results in increased expression of SUGCT mRNA23811387
C005556propionaldehydepropionaldehyde results in increased expression of SUGCT mRNA26079696
D011441PropylthiouracilPropylthiouracil results in decreased expression of SUGCT mRNA24780913
C012526quercitrinquercitrin results in increased expression of SUGCT mRNA25193878
D012402RotenoneRotenone results in increased expression of SUGCT mRNA19013527
C016104sodium bichromatesodium bichromate results in decreased expression of SUGCT mRNA25993096
D013853ThioacetamideThioacetamide results in decreased expression of SUGCT mRNA23411599
D014050TolueneToluene results in decreased expression of SUGCT mRNA28245982
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of SUGCT mRNA"26179874
D014520UrethaneUrethane results in decreased expression of SUGCT mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of SUGCT mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of SUGCT mRNA29154799
D014635Valproic AcidValproic Acid results in increased expression of SUGCT mRNA23179753|2627250
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of SUGCT gene25560391
C025643vinclozolinvinclozolin results in increased expression of SUGCT mRNA23034163
C029297vinylidene chloridevinylidene chloride results in decreased expression of SUGCT mRNA26682919
C088658zoledronic acidzoledronic acid results in increased expression of SUGCT mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0047369succinate-hydroxymethylglutarate CoA-transferase activity-IDA23893049  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005739mitochondrion-IDA23893049  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal