Gene info: ID 79817

SNP ID	Position	Alleles	Trait	Variation Type
rs1058326	chr9:27447091 (GRCh38.p7)	G>A	alcohol dependence	SNV(Single Nucleotide Variation)
rs2589053	chr9:27441539 (GRCh38.p7)	C>T	alcohol dependence	SNV(Single Nucleotide Variation)

Gene Symbol	Pearson Correlation Coefficient
PSEN1	0.871
FRYL	0.864
SPTLC2	0.863
JAM3	0.855
STRN	0.849
EDIL3	0.848
PTPDC1	0.844
SLC44A1	0.842
DIP2B	0.84
DOCK10	0.84

Gene Symbol	Pearson Correlation Coefficient
OR4F5	-0.375
OR4F29	-0.371
WNT7B	-0.321
TNNT1	-0.275
SLC29A4	-0.27
GOLGA6L1	-0.27
PPP1R3G	-0.264
DIO2	-0.263
RNF43	-0.259
PAX2	-0.246

DrugBank
CTD

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MOB3B mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MOB3B mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MOB3B mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MOB3B mRNA"	27188386
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of MOB3B mRNA	27153756
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased methylation of MOB3B gene	27153756
D000447	Aldehydes	Aldehydes results in increased expression of MOB3B mRNA	25014914
C015001	arsenite	arsenite results in increased methylation of MOB3B promoter	23974009
C547126	AZM551248	AZM551248 results in decreased expression of MOB3B mRNA	22323515
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of MOB3B mRNA	20064835
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of MOB3B mRNA	22316170
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of MOB3B mRNA	21964900
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MOB3B mRNA"	19150397
C006780	bisphenol A	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MOB3B mRNA	28628672
C006780	bisphenol A	bisphenol A results in decreased expression of MOB3B mRNA	25181051
C006780	bisphenol A	bisphenol A results in increased methylation of MOB3B gene	28505145
C018475	butyraldehyde	butyraldehyde results in increased expression of MOB3B mRNA	26079696
D019256	Cadmium Chloride	Cadmium Chloride results in increased methylation of MOB3B promoter	22457795
D003300	Copper	[NSC 689534 binds to Copper] which results in decreased expression of MOB3B mRNA	20971185
D019327	Copper Sulfate	Copper Sulfate results in increased expression of MOB3B mRNA	18579281
C030973	cupric oxide	cupric oxide results in decreased expression of MOB3B mRNA	22077320
D003471	Cuprizone	Cuprizone results in increased expression of MOB3B mRNA	26577399
D016572	Cyclosporine	Cyclosporine results in decreased expression of MOB3B mRNA	20106945
D016572	Cyclosporine	Cyclosporine results in increased expression of MOB3B mRNA	27989131
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MOB3B mRNA	28628672
D003976	Diazinon	Diazinon results in increased methylation of MOB3B gene	22964155
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased expression of MOB3B mRNA	21266533
D002945	Cisplatin	[Cisplatin co-treated with jinfukang] results in decreased expression of MOB3B mRNA	27392435
D002945	Cisplatin	Cisplatin results in decreased expression of MOB3B mRNA	27392435
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of MOB3B mRNA	19850644
D004051	Diethylhexyl Phthalate	PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of MOB3B mRNA]	19850644
C118739	entinostat	entinostat results in decreased expression of MOB3B mRNA	26272509
C118739	entinostat	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MOB3B mRNA"	27188386
C039281	furan	furan results in increased expression of MOB3B mRNA	24183702
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MOB3B mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MOB3B mRNA	28628672
C544151	jinfukang	[Cisplatin co-treated with jinfukang] results in decreased expression of MOB3B mRNA	27392435
C004925	methylmercuric chloride	methylmercuric chloride results in decreased expression of MOB3B mRNA	28001369
D015655	1-Methyl-4-phenylpyridinium	1-Methyl-4-phenylpyridinium results in decreased expression of MOB3B mRNA	24810058
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in decreased expression of MOB3B mRNA"	25620056
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in decreased expression of MOB3B mRNA"	25620056
D009532	Nickel	Nickel results in increased expression of MOB3B mRNA	25583101
C558013	NSC 689534	[NSC 689534 binds to Copper] which results in decreased expression of MOB3B mRNA	20971185
C046012	pentanal	pentanal results in increased expression of MOB3B mRNA	26079696
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid results in decreased expression of MOB3B mRNA	27153767
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of MOB3B mRNA	19710929
C027373	potassium chromate(VI)	potassium chromate(VI) results in increased expression of MOB3B mRNA	22714537
D011374	Progesterone	Progesterone results in increased expression of MOB3B mRNA	23018184
D011374	Progesterone	Progesterone results in increased expression of MOB3B mRNA	20864642
C005556	propionaldehyde	propionaldehyde results in increased expression of MOB3B mRNA	26079696
D011441	Propylthiouracil	Propylthiouracil results in decreased expression of MOB3B mRNA	24780913
C513428	pyrachlostrobin	pyrachlostrobin results in increased expression of MOB3B mRNA	27029645
D012822	Silicon Dioxide	Silicon Dioxide analog results in increased expression of MOB3B mRNA	25895662
D012822	Silicon Dioxide	Silicon Dioxide results in decreased expression of MOB3B mRNA	23221170
D012906	Smoke	Smoke results in decreased expression of MOB3B mRNA	21095227
D018038	Sodium Selenite	Sodium Selenite results in increased expression of MOB3B mRNA	18175754
D012999	Soman	Soman results in increased expression of MOB3B mRNA	19281266
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of MOB3B mRNA	22298810
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of MOB3B mRNA	21570461
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of MOB3B mRNA	26290441
D014212	Tretinoin	Tretinoin results in decreased expression of MOB3B mRNA	21934132
C012589	trichostatin A	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MOB3B mRNA"	27188386
C012589	trichostatin A	trichostatin A results in decreased expression of MOB3B mRNA	24935251\|2627250
C057693	troglitazone	troglitazone results in decreased expression of MOB3B mRNA	28973697
D014635	Valproic Acid	Valproic Acid affects the expression of MOB3B mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in decreased expression of MOB3B mRNA	28001369
D014635	Valproic Acid	Valproic Acid results in decreased methylation of MOB3B gene	29154799
D014635	Valproic Acid	Valproic Acid results in increased expression of MOB3B mRNA	23179753\|2718838
C025643	vinclozolin	vinclozolin results in decreased expression of MOB3B mRNA	23869203
C029297	vinylidene chloride	vinylidene chloride results in decreased expression of MOB3B mRNA	26682919

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005515	protein binding	-	IPI	16189514 19060904
GO:0046872	metal ion binding	-	IEA	-

Gene: MOB3B

ANCO-SNPs

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Drugs/Compounds

There is no DrugBank record for this gene !

GO/Pathway

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)