Gene: BAALC

79870
-
BAALC, MAP3K1 and KLF4 binding
protein-coding
8q22.3
Ensembl:ENSG00000164929 MIM:606602 Vega:OTTHUMG00000164782 UniprotKB:Q8WXS3
NC_000008.11
PubMed
0   ANCO-SNPs
ND
1   
5.899e-1 (AD)  7.199e-1 (ND)   (Frontal_Cortex)
2.743e-1 (AD)  6.078e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SRI0.866
PPP2CB0.865
TMA70.864
C18orf320.859
COX200.859
SRP90.857
DAZAP20.856
RAB5C0.855
NCBP20.851
SNX50.842

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.848
OR4F29-0.838
RXFP2-0.145
CHAT-0.144
DRD3-0.141
FAM169B-0.141
GPR101-0.137
FAT2-0.132
ENTHD1-0.13
SAG-0.129

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BAALC mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BAALC mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BAALC mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BAALC mRNA"27188386
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of BAALC gene27153756
D001151ArsenicArsenic affects the methylation of BAALC gene25304211
C006632arsenic trioxidearsenic trioxide results in decreased expression of BAALC mRNA19128835|2670570
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of BAALC mRNA20660070
C006780bisphenol Abisphenol A affects the expression of BAALC mRNA25181051
C006780bisphenol Abisphenol A affects the methylation of BAALC promoter27415467
D002220CarbamazepineCarbamazepine affects the expression of BAALC mRNA25979313
D004390ChlorpyrifosChlorpyrifos results in increased expression of BAALC mRNA18668222
D003042CocaineCocaine results in decreased expression of BAALC mRNA18355967
C118739entinostatentinostat results in decreased expression of BAALC mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BAALC mRNA"27188386
C074283estradiol 3-benzoateestradiol 3-benzoate results in increased methylation of BAALC promoter27415467
C039281furanfuran results in increased expression of BAALC mRNA27387713
D007854LeadLead affects the expression of BAALC mRNA28903495
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of BAALC mRNA28001369
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of BAALC mRNA"25554681
C028007nickel monoxidenickel monoxide results in increased expression of BAALC mRNA19167457
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of BAALC mRNA20660070
D014212TretinoinTretinoin results in increased expression of BAALC mRNA21934132|2372400
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BAALC mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of BAALC mRNA24935251|2627250
D014501UraniumUranium affects the expression of BAALC mRNA15672453
C005460uranyl acetateuranyl acetate affects the expression of BAALC mRNA15672453
D014635Valproic AcidValproic Acid affects the expression of BAALC mRNA25979313
D014635Valproic AcidValproic Acid results in decreased methylation of BAALC gene29154799
D014635Valproic AcidValproic Acid results in increased expression of BAALC mRNA19101580|2317975

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA-  
GO:0005737cytoplasm-IDA11707601  
GO:0005829cytosol-IDA-  
GO:0014069postsynaptic density-IEA-  
GO:0030054cell junction-IEA-  
GO:0043005neuron projection-IEA-  
GO:0045121membrane raft-IEA-  
GO:0045211postsynaptic membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
21618603Evidence for gene-environment interaction in a genome wide study of nonsyndromic cleft palate. (2011 Sep)Beaty THGenet Epidemiol