Gene: C10orf88

80007
-
chromosome 10 open reading frame 88
protein-coding
10q26.13
Ensembl:ENSG00000119965 Vega:OTTHUMG00000019190 UniprotKB:Q9H8K7
NC_000010.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.174e-1 (AD)  1.071e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs17653439chr10:122930775 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC25A460.955
CUL20.954
CHIC10.953
PARG0.951
C2CD50.95
TADA10.95
PIK3CB0.95
MTMR90.949
NAPG0.949
TRIM230.949

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.456
CSAG1-0.443
SYDE1-0.415
OR4F29-0.414
HEY2-0.414
MTRNR2L10-0.411
RAB13-0.408
ASB4-0.407
MAPKAPK3-0.407
MTRNR2L9-0.404

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of C10ORF88 mRNA26690555
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of C10ORF88 mRNA20106945|2163298
C006780bisphenol Abisphenol A affects the expression of C10ORF88 mRNA25181051
D019327Copper SulfateCopper Sulfate results in decreased expression of C10ORF88 mRNA19549813
C000944dicrotophosdicrotophos results in decreased expression of C10ORF88 mRNA28302478
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of C10ORF88 mRNA23649840
C492448ICG 001ICG 001 results in decreased expression of C10ORF88 mRNA26191083
C544151jinfukangjinfukang results in decreased expression of C10ORF88 mRNA27392435
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of C10ORF88 mRNA23649840
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in increased expression of C10ORF88 mRNA19095052
D010936Plant ExtractsPlant Extracts results in increased expression of C10ORF88 mRNA23557933
D014635Valproic AcidValproic Acid affects the expression of C10ORF88 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of C10ORF88 mRNA23179753|2493525

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0042802identical protein binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal