Gene: TMEM156

80008
-
transmembrane protein 156
protein-coding
4p14
Ensembl:ENSG00000121895 Vega:OTTHUMG00000128582 UniprotKB:Q8N614
NC_000004.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.181e-2 (AD)  6.729e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs4974983chr4:38969437 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CMTM70.879
SYK0.873
CD860.872
C3AR10.87
SLC7A70.87
BTK0.87
PTPRC0.864
CD370.862
WAS0.862
PARVG0.861

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ATP2C2-0.465
KCNK4-0.461
MARCH4-0.456
TMEM179-0.454
ATOH7-0.453
SLC7A4-0.443
LRTM2-0.437
KCNIP3-0.437
SPRN-0.432
NEUROD6-0.428

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D020106AcrylamideAcrylamide results in increased expression of TMEM156 mRNA28959563
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of TMEM156 mRNA"18687144
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TMEM156 mRNA22178795
C006780bisphenol Abisphenol A results in decreased expression of TMEM156 mRNA25181051
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of TMEM156 mRNA20971185
D003471CuprizoneCuprizone results in increased expression of TMEM156 mRNA27523638
D016572CyclosporineCyclosporine results in decreased expression of TMEM156 mRNA27989131
D002117CalcitriolCalcitriol results in increased expression of TMEM156 mRNA16002434
D004317DoxorubicinTMEM156 protein affects the susceptibility to Doxorubicin16217747
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in decreased expression of TMEM156 mRNA23649840
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TMEM156 mRNA25613284
C544151jinfukangjinfukang results in decreased expression of TMEM156 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of TMEM156 mRNA24796395|2530787
C561695(+)-JQ1 compound[PD 0325901 co-treated with (+)-JQ1 compound] results in decreased expression of TMEM156 mRNA25119042
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of TMEM156 mRNA23649840
D016685MitomycinTMEM156 protein affects the susceptibility to Mitomycin16217747
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of TMEM156 mRNA20971185
C558013NSC 689534NSC 689534 results in increased expression of TMEM156 mRNA20971185
D052638Particulate MatterParticulate Matter results in increased expression of TMEM156 mRNA22178795
C506614PD 0325901[PD 0325901 co-treated with (+)-JQ1 compound] results in decreased expression of TMEM156 mRNA25119042
C506614PD 0325901PD 0325901 results in decreased expression of TMEM156 mRNA25119042
D010936Plant ExtractsPlant Extracts results in increased expression of TMEM156 mRNA23557933
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of TMEM156 mRNA22714537
D011794QuercetinQuercetin results in increased expression of TMEM156 mRNA21632981
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of TMEM156 mRNA25895662
D012822Silicon DioxideSilicon Dioxide results in increased expression of TMEM156 mRNA25351596
D012906SmokeSmoke results in increased expression of TMEM156 mRNA21095227
D018038Sodium SeleniteSodium Selenite results in increased expression of TMEM156 mRNA24383545
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TMEM156 mRNA20106945|2163298
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TMEM156 mRNA25613284
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of TMEM156 mRNA"26179874
D014635Valproic AcidValproic Acid results in decreased expression of TMEM156 mRNA29154799
D014638VanadatesVanadates results in increased expression of TMEM156 mRNA22714537
D014747VinblastineTMEM156 protein affects the susceptibility to Vinblastine16217747

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal