Gene: FAM192A

80011
C16orf94|CDA018|CDA10|NIP30
family with sequence similarity 192 member A
protein-coding
16q13
Ensembl:ENSG00000172775 MIM:617766 Vega:OTTHUMG00000176660 UniprotKB:Q9GZU8
NC_000016.10
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.490e-2 (AD)  7.300e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs767505chr16:57178738 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ENOPH10.951
DNAJC80.949
YWHAQ0.946
CALM20.946
TCEAL40.942
PEBP10.94
OAZ20.938
MRFAP10.936
CHMP4B0.936
HTATSF10.935

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.825
OR4F5-0.813
MTRNR2L6-0.306
MTRNR2L10-0.297
MTRNR2L9-0.287
C8orf74-0.256
TTLL10-0.253
MTRNR2L3-0.252
KCNK5-0.25
KCNJ15-0.249

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of FAM192A mRNA26690555
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of FAM192A gene27153756
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of FAM192A mRNA24449571
D001280AtrazineAtrazine results in decreased expression of FAM192A mRNA22378314
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of FAM192A mRNA26238291
C006780bisphenol Abisphenol A affects the expression of FAM192A mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of FAM192A mRNA25181051
C013418bromfenacoumbromfenacoum results in decreased expression of FAM192A protein28903499
D004390ChlorpyrifosChlorpyrifos results in increased expression of FAM192A protein16790487
D019327Copper SulfateCopper Sulfate results in decreased expression of FAM192A mRNA19549813
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of FAM192A protein23301498
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FAM192A mRNA22079256
C010974glyphosateglyphosate results in increased expression of FAM192A mRNA26302742
C492448ICG 001ICG 001 results in increased expression of FAM192A mRNA26191083
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FAM192A mRNA25613284
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of FAM192A mRNA25613284
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of FAM192A mRNA23458150
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of FAM192A mRNA"26251327
D008777MethyltestosteroneMethyltestosterone results in decreased expression of FAM192A mRNA29191790
D010936Plant ExtractsPlant Extracts results in increased expression of FAM192A mRNA23557933
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FAM192A mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of FAM192A mRNA22079256|2271453
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FAM192A mRNA25613284
D014635Valproic AcidValproic Acid results in decreased methylation of FAM192A gene29154799
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of FAM192A gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI25416956  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal