Gene: NR4A3

8013
CHN|CSMF|MINOR|NOR1|TEC
nuclear receptor subfamily 4 group A member 3
protein-coding
9q31.1
Ensembl:ENSG00000119508 MIM:600542 Vega:OTTHUMG00000021030 UniprotKB:Q92570
NG_028910.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.602e-1 (AD)  7.591e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FOSB0.814
EGR20.753
EGR10.726
NPAS40.697
NR4A20.693
NR4A10.69
ZNF3310.661
JUN0.645
PPP1R15A0.641
EGR40.623

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
P2RY14-0.253
OTOS-0.235
CDA-0.215
CYP4B1-0.215
OR7C1-0.212
TMEM204-0.206
C14orf178-0.199
TRDN-0.198
CTNNA3-0.188
OR4F5-0.187

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01254DasatinibSmall Molecule302962-49-8Approved|InvestigationalTarget
ID Drug Name Action PubMed
C04676015-acetyldeoxynivalenol15-acetyldeoxynivalenol results in increased expression of NR4A3 mRNA23792671
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in increased expression of NR4A3 mRNA28329830
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of NR4A3 mRNA19933214
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of NR4A3 mRNA"23829299
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of NR4A3 mRNA"25614096
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of NR4A3 mRNA"19114083
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of NR4A3 mRNA]12710931
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of NR4A3 mRNA"18648102
C5830744,4'-hexafluorisopropylidene diphenol"4,4'-hexafluorisopropylidene diphenol results in increased expression of NR4A3 mRNA"27567155
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR4A3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR4A3 mRNA"27188386
D020106AcrylamideAcrylamide results in decreased expression of NR4A3 mRNA22197712
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in increased expression of NR4A3 mRNA"23195993
D024502alpha-Tocopherolalpha-Tocopherol deficiency results in increased expression of NR4A3 mRNA24657723
D000643Ammonium ChlorideAmmonium Chloride affects the expression of NR4A3 mRNA16483693
D000936Antigen-Antibody ComplexAntigen-Antibody Complex results in increased expression of NR4A3 mRNA25451590
D000936Antigen-Antibody ComplexCyclosporine inhibits the reaction [Antigen-Antibody Complex results in increased expression of NR4A3 mRNA]25451590
D000936Antigen-Antibody Complexshikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of NR4A3 mRNA]25451590
D001151ArsenicArsenic results in decreased expression of NR4A3 mRNA19654921
C015001arsenitearsenite affects the expression of NR4A3 mRNA22959463
C015001arsenitearsenite results in increased methylation of NR4A3 promoter23974009
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of NR4A3 mRNA"25757056
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of NR4A3 mRNA"18687144
D001205Ascorbic Acid[Tretinoin co-treated with Ascorbic Acid] results in increased expression of NR4A3 mRNA16443354
D001241AspirinAspirin results in increased expression of NR4A3 mRNA15928584
D016589AstemizoleAstemizole results in increased expression of NR4A3 mRNA20221588
D001280AtrazineAtrazine results in increased expression of NR4A3 mRNA18461179
D001379AzathioprineAzathioprine results in decreased expression of NR4A3 mRNA19192274
C028559bathocuproine sulfonate[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA]15477007
D001554BenzeneBenzene results in increased expression of NR4A3 mRNA19162166
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NR4A3 mRNA21839799
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in increased expression of NR4A3 mRNA26186136
C006780bisphenol Abisphenol A results in decreased expression of NR4A3 mRNA27685785
C006780bisphenol Abisphenol A affects the methylation of NR4A3 promoter27334623
C006780bisphenol Abisphenol A results in decreased expression of NR4A3 mRNA25594700
C006780bisphenol Abisphenol A results in increased expression of NR4A3 mRNA14967926
C006780bisphenol A[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NR4A3 promoter23359474
C006780bisphenol Abisphenol A results in decreased expression of NR4A3 mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of NR4A3 mRNA26141625
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of NR4A3 mRNA17553608
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR4A3 mRNA22079614
C027561butylbenzyl phthalatebutylbenzyl phthalate results in decreased expression of NR4A3 mRNA19560483
C018475butyraldehydebutyraldehyde results in increased expression of NR4A3 mRNA26079696
C028031cadmium acetatecadmium acetate results in increased expression of NR4A3 mRNA12965115|1501665
C028031cadmium acetatecadmium acetate results in increased expression of NR4A3 mRNA15016657
D000001CalcimycinCalcimycin results in increased expression of NR4A3 mRNA25451590
D000001Calcimycinshikonin inhibits the reaction [Calcimycin results in increased expression of NR4A3 mRNA]25451590
C010063carbonyl sulfidecarbonyl sulfide results in decreased expression of NR4A3 mRNA19395590
D002713Chlorine[Ozone co-treated with Chlorine] results in decreased expression of NR4A3 mRNA18636392
C418118CI 1044CI 1044 results in increased expression of NR4A3 mRNA17569694
D003042CocaineCocaine results in increased expression of NR4A3 mRNA27899881
D005576ColforsinNR4A3 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]19822197
D019327Copper SulfateCopper Sulfate results in increased expression of NR4A3 mRNA19549813
C030973cupric oxidecupric oxide results in increased expression of NR4A3 mRNA22077320
C030973cupric oxidecupric oxide results in increased expression of NR4A3 protein22077320
D003471CuprizoneCuprizone results in decreased expression of NR4A3 mRNA26577399
D016572CyclosporineCyclosporine inhibits the reaction [Antigen-Antibody Complex results in increased expression of NR4A3 mRNA]25451590
C089595cylindrospermopsincylindrospermopsin results in increased expression of NR4A3 mRNA24921660
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of NR4A3 mRNA24317228
D003847DeoxyglucoseNR4A3 protein promotes the reaction [[INS protein results in increased localization of SLC2A4 protein] which results in increased uptake of Deoxyglucose]17785466
D003847DeoxyglucoseNR4A3 protein promotes the reaction [INS protein results in increased uptake of Deoxyglucose]17785466
C007262deoxynivalenoldeoxynivalenol results in increased expression of NR4A3 mRNA26763390
D003907DexamethasoneDexamethasone results in increased expression of NR4A3 mRNA25047013
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of NR4A3 mRNA17361019|2126653
D003993Dibutyl Phthalate[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NR4A3 promoter23359474
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of NR4A3 mRNA19560483
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of NR4A3 mRNA21266533|2174549
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of NR4A3 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of NR4A3 mRNA27392435
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of NR4A3 mRNA26924002
D004051Diethylhexyl Phthalate[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of NR4A3 promoter23359474
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of NR4A3 mRNA19560483
C034171di-n-pentyl phthalatedi-n-pentyl phthalate results in decreased expression of NR4A3 mRNA19560483
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of NR4A3 mRNA22079256
C063007exoenzyme C3, Clostridium botulinum"exoenzyme C3, Clostridium botulinum results in decreased expression of NR4A3 mRNA"16005304
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in increased expression of NR4A3 mRNA28329830
D005473FluoxetineFluoxetine results in decreased expression of NR4A3 mRNA17033635
D005492Folic AcidFolic Acid results in decreased expression of NR4A3 mRNA25006883
C069837fullerene C60fullerene C60 results in decreased expression of NR4A3 mRNA19167457
C056507gemcitabinegemcitabine results in increased expression of NR4A3 mRNA17039268
D005839GentamicinsGentamicins results in decreased expression of NR4A3 mRNA22061828
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of NR4A3 mRNA]16005304
C004312glycidolglycidol results in decreased expression of NR4A3 mRNA24915197
D006052Gold Sodium ThiomalateGold Sodium Thiomalate results in decreased expression of NR4A3 mRNA19192274
D006220HaloperidolHaloperidol results in increased expression of NR4A3 mRNA19695244
D017313FenretinideFenretinide results in increased expression of NR4A3 mRNA28973697
D015759Ionomycin[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA]15477007
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA15477007
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of NR4A3 mRNA27392435
C544151jinfukangjinfukang results in decreased expression of NR4A3 mRNA27392435
C098607JP8 aviation fuelJP8 aviation fuel affects the expression of NR4A3 mRNA17085751
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of NR4A3 protein17337753
D007608Kainic AcidKainic Acid results in increased expression of NR4A3 mRNA19700661
D007649KetamineKetamine results in decreased expression of NR4A3 mRNA20080153
C008261lead acetatelead acetate results in increased expression of NR4A3 mRNA21891863
C045463leflunomideleflunomide results in increased expression of NR4A3 mRNA28988120
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of NR4A3 mRNA"24972896
D008558MelphalanMelphalan results in increased expression of NR4A3 mRNA22363485
D008694Methamphetamine[Methamphetamine co-treated with SCH 23390] results in increased expression of NR4A3 mRNA19564919
D008694MethamphetamineMethamphetamine results in increased expression of NR4A3 mRNA19564919
D008727MethotrexateMethotrexate results in decreased expression of NR4A3 mRNA19192274
D008731MethoxychlorMethoxychlor results in increased methylation of NR4A3 gene23303685
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of NR4A3 mRNA26011545
D0156551-Methyl-4-phenylpyridinium2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of NR4A3 mRNA]12710931
D008775MethylprednisoloneMethylprednisolone results in decreased expression of NR4A3 mRNA19192274
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of NR4A3 mRNA]16005304
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of NR4A3 mRNA19822197
D009151Mustard GasMustard Gas results in increased expression of NR4A3 mRNA18988085
C518313N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine"N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine results in increased expression of NR4A3 mRNA"19695244
D009281NaphthalenesNaphthalenes results in increased expression of NR4A3 protein17337753
D009532NickelNickel results in increased expression of NR4A3 mRNA23195993|2558310
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of NR4A3 mRNA17616710
D010126Ozone[Ozone co-treated with Chlorine] results in decreased expression of NR4A3 mRNA18636392
D010126OzoneOzone results in increased expression of NR4A3 mRNA16716893
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of NR4A3 mRNA18593933
D026023PermethrinPermethrin results in increased expression of NR4A3 mRNA19017407
D010656PhenylephrinePhenylephrine results in increased expression of NR4A3 mRNA18158353
C060836pioglitazonepioglitazone results in increased expression of NR4A3 mRNA17785466
C006253pirinixic acidpirinixic acid results in increased expression of NR4A3 mRNA16985257
D010894PiroxicamPiroxicam results in decreased expression of NR4A3 mRNA19192274
D010938Plant OilsPlant Oils results in increased expression of NR4A3 mRNA23370395
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of NR4A3 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of NR4A3 mRNA22079256
D011192Potassium DichromatePotassium Dichromate results in increased expression of NR4A3 mRNA23608068
D011239PrednisolonePrednisolone results in decreased expression of NR4A3 mRNA19192274
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of NR4A3 mRNA19162173
D011441PropylthiouracilPropylthiouracil results in increased expression of NR4A3 mRNA24780913
C010313pseudocumenepseudocumene results in increased expression of NR4A3 protein17337753
C020972pyrrolidine dithiocarbamic acid[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA]15477007
D011794QuercetinQuercetin affects the expression of NR4A3 mRNA18178720
D020849Raloxifene Hydrochloride[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA19059307
C534628SCH 23390[Methamphetamine co-treated with SCH 23390] results in increased expression of NR4A3 mRNA19564919
C410733scriptaidscriptaid affects the expression of NR4A3 mRNA18813790
C016101shikoninshikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of NR4A3 mRNA]25451590
C016101shikoninshikonin inhibits the reaction [Calcimycin results in increased expression of NR4A3 mRNA]25451590
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of NR4A3 mRNA25895662
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of NR4A3 mRNA23806026
D012822Silicon DioxideSilicon Dioxide results in increased expression of NR4A3 mRNA22300531|2535159
D012822Silicon DioxideSilicon Dioxide results in increased expression of NR4A3 mRNA23221170
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of NR4A3 mRNA]16005304
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of NR4A3 mRNA]16005304
D019821SimvastatinSimvastatin results in decreased expression of NR4A3 mRNA16005304
C017947sodium arsenitesodium arsenite results in increased expression of NR4A3 mRNA alternative form21281968
D012999SomanSoman results in increased expression of NR4A3 mRNA19281266
D020058StyreneStyrene results in decreased expression of NR4A3 mRNA28951217
D013629Tamoxifen[Tamoxifen co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA19059307
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of NR4A3 mRNA19933214|2405805
D013755Tetradecanoylphorbol Acetate[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA]15477007
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA15477007
D013755Tetradecanoylphorbol Acetate[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A3 mRNA16979875
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA25613284
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of NR4A3 mRNA28065790
C483909torcetrapibtorcetrapib results in increased expression of NR4A3 mRNA19164467|2322803
D014212Tretinoin[Tretinoin co-treated with Ascorbic Acid] results in increased expression of NR4A3 mRNA16443354
D014212TretinoinTretinoin results in increased expression of NR4A3 mRNA23724009
C057693troglitazonetroglitazone results in decreased expression of NR4A3 mRNA28973697
C057693troglitazonetroglitazone results in increased expression of NR4A3 mRNA17785466
C022884undecaneundecane results in increased expression of NR4A3 protein17337753
D014520UrethaneUrethane results in increased expression of NR4A3 mRNA28818685
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NR4A3 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of NR4A3 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of NR4A3 mRNA28001369
D014635Valproic AcidValproic Acid results in increased expression of NR4A3 mRNA23179753|2438349
D001335Vehicle EmissionsVehicle Emissions results in increased expression of NR4A3 mRNA19465080
C025643vinclozolinvinclozolin affects the expression of NR4A3 mRNA19015723
C108830Y 27632Y 27632 results in decreased expression of NR4A3 mRNA16005304
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of NR4A3 mRNA18593933
D015032Zinc[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A3 mRNA16979875
D015032ZincZinc deficiency results in decreased expression of NR4A3 mRNA19111725
D019287Zinc SulfateZinc Sulfate results in decreased expression of NR4A3 mRNA27215404

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding-IBA21873635  
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding-IBA21873635  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IBA21873635  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IDA20558821  
GO:0001223transcription coactivator binding-IEA-  
GO:0003677DNA binding-NAS8634690  
GO:0003707steroid hormone receptor activity-IEA-  
GO:0004887thyroid hormone receptor activity-TAS8570200  
GO:0005515protein binding-IPI12543801  
GO:0008270zinc ion binding-IEA-  
GO:0019901protein kinase binding-IPI25852083  
GO:0035035histone acetyltransferase binding-IEA-  
GO:0035259glucocorticoid receptor binding-IBA21873635  
GO:0035259glucocorticoid receptor binding-IEA-  
GO:0035497cAMP response element binding-ISS-  
GO:0042803protein homodimerization activity-ISS-  
GO:0043565sequence-specific DNA binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-ISS-  
GO:0001707mesoderm formation-IEA-  
GO:0006367transcription initiation from RNA polymerase II promoter-TAS-  
GO:0007369gastrulation-ISS-  
GO:0007411axon guidance-IEA-  
GO:0009444pyruvate oxidation-ISS-  
GO:0010613positive regulation of cardiac muscle hypertrophy-ISS-  
GO:0010828positive regulation of glucose transmembrane transport-IDA24022864  
GO:0021766hippocampus development-IEA-  
GO:0030522intracellular receptor signaling pathway-IEA-  
GO:0030534adult behavior-IEA-  
GO:0031100animal organ regeneration-IEA-  
GO:0032765positive regulation of mast cell cytokine production-ISS-  
GO:0035726common myeloid progenitor cell proliferation-ISS-  
GO:0038097positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway-ISS-  
GO:0042542response to hydrogen peroxide-IEA-  
GO:0043303mast cell degranulation-ISS-  
GO:0043401steroid hormone mediated signaling pathway-IEA-  
GO:0043524negative regulation of neuron apoptotic process-IEA-  
GO:0044320cellular response to leptin stimulus-ISS-  
GO:0045333cellular respiration-ISS-  
GO:0045444fat cell differentiation-ISS-  
GO:0045652regulation of megakaryocyte differentiation-TAS-  
GO:0045787positive regulation of cell cycle-IEA-  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA20558821  
GO:0046321positive regulation of fatty acid oxidation-ISS-  
GO:0048008platelet-derived growth factor receptor signaling pathway-IDA23554459  
GO:0048660regulation of smooth muscle cell proliferation-IDA25852083  
GO:0048661positive regulation of smooth muscle cell proliferation-ISS-  
GO:0048752semicircular canal morphogenesis-IEA-  
GO:0050679positive regulation of epithelial cell proliferation-ISS-  
GO:0050885neuromuscular process controlling balance-IEA-  
GO:0060005vestibular reflex-IEA-  
GO:0061469regulation of type B pancreatic cell proliferation-ISS-  
GO:0071376cellular response to corticotropin-releasing hormone stimulus-IBA21873635  
GO:0071376cellular response to corticotropin-releasing hormone stimulus-ISS-  
GO:0071870cellular response to catecholamine stimulus-ISS-  
GO:0097009energy homeostasis-ISS-  
GO:1900625positive regulation of monocyte aggregation-IMP20558821  
GO:1903208negative regulation of hydrogen peroxide-induced neuron death-ISS-  
GO:1904707positive regulation of vascular smooth muscle cell proliferation-IGI23554459  
GO:1904754positive regulation of vascular associated smooth muscle cell migration-IGI23554459  
GO:2000108positive regulation of leukocyte apoptotic process-IEA-  
GO:2000253positive regulation of feeding behavior-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-NAS8634690  
GO:0005654nucleoplasm-TAS-  
GO:0005667transcription factor complex-IBA21873635  
GO:0005667transcription factor complex-IEA-  
GO:0042629mast cell granule-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-383280Nuclear Receptor transcription pathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8878171Transcriptional regulation by RUNX1TAS
R-HSA-8936459RUNX1 regulates genes involved in megakaryocyte differentiation and platelet functionTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
20659174Replicated association of the NR4A3 gene with smoking behaviour in schizophrenia and in bipolar disorder. (2010 Nov)Novak GGenes Brain Behav