Gene: OR12D3

81797
hs6M1-27
olfactory receptor family 12 subfamily D member 3
protein-coding
6p22.1
Ensembl:ENSG00000112462 Vega:OTTHUMG00000031051 UniprotKB:Q9UGF7
NC_000006.12
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LRRC300.934
CDY2A0.924
OR5M10.924
OR5T20.924
KRTAP6-20.924
OR4C120.924
KRTAP27-10.924
OR5W20.924
MAGEB50.924
OR8K30.924

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
C16orf95-0.256
SLC1A4-0.247
NOG-0.244
SORCS2-0.239
MMP15-0.236
TM7SF2-0.233
TMEM221-0.233
HHATL-0.232
HDAC11-0.228
FAM184A-0.227

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in decreased expression of OR12D3 mRNA26690555
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of OR12D3 mRNA"17331233

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004888transmembrane signaling receptor activity-IBA21873635  
GO:0004930G-protein coupled receptor activity-IEA-  
GO:0004984olfactory receptor activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0007186G-protein coupled receptor signaling pathway-IBA21873635  
GO:0050911detection of chemical stimulus involved in sensory perception of smell-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS-  
KEGG ID KEGG Term
hsa04740Olfactory transduction
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-381753Olfactory Signaling PathwayTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-418555G alpha (s) signalling eventsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18939942Association of smoking behavior with an odorant receptor allele telomeric to the human major histocompatibility complex. (2008 Dec)Santos PSGenet Test