Gene: RBM10

8241
DXS8237E|GPATC9|GPATCH9|S1-1|TARPS|ZRANB5
RNA binding motif protein 10
protein-coding
Xp11.3
Ensembl:ENSG00000182872 MIM:300080 Vega:OTTHUMG00000021432 UniprotKB:P98175
NG_012548.1
PubMed
0   ANCO-SNPs
ND
3   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TRMT10.932
SF10.932
GGA10.931
GAK0.928
CXXC10.926
SH2B10.922
U2AF20.919
C7orf260.917
ATG4B0.917
TMEM161A0.917

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.742
OR4F29-0.702
VNN2-0.281
C9orf153-0.275
CEACAM3-0.27
MEI4-0.265
DNASE1L3-0.262
CXCR2-0.261
KCNJ15-0.26
TFPI2-0.259

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C49562614-deoxy-11,12-didehydroandrographolide"14-deoxy-11,12-didehydroandrographolide results in decreased expression of RBM10 mRNA"22101062
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RBM10 mRNA"19167446
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of RBM10 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of RBM10 mRNA"21346803
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of RBM10 mRNA"18648102
D000082AcetaminophenAcetaminophen affects the expression of RBM10 mRNA17562736
D000643Ammonium ChlorideAmmonium Chloride affects the expression of RBM10 mRNA16483693
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of RBM10 mRNA22228805
C006780bisphenol Abisphenol A results in increased expression of RBM10 mRNA25181051
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RBM10 mRNA"19167446
D002945CisplatinCisplatin results in decreased expression of RBM10 mRNA27392435
D001556LindaneLindane results in decreased expression of RBM10 mRNA17785943
D008727MethotrexateMethotrexate affects the expression of RBM10 mRNA18502557
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of RBM10 mRNA26011545
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of RBM10 mRNA"20188158
D009151Mustard GasMustard Gas results in increased phosphorylation of RBM10 protein19845377
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of RBM10 mRNA"25620056
C006253pirinixic acidpirinixic acid results in decreased expression of RBM10 mRNA18445702
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of RBM10 mRNA16497877
D012643SeleniumSelenium results in increased expression of RBM10 mRNA19244175
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of RBM10 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of RBM10 mRNA19465110
D014635Valproic AcidValproic Acid results in increased methylation of RBM10 gene29154799
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of RBM10 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-HDA22658674  
GO:0005515protein binding-IPI22365833  25416956  26871637  
GO:0035198miRNA binding-IDA28431233  
GO:0042802identical protein binding-IPI22365833  
GO:0044877protein-containing complex binding-IDA17707232  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000381regulation of alternative mRNA splicing, via spliceosome-IEA-  
GO:0006397mRNA processing-IEA-  
GO:0008150biological_process-ND-  
GO:0008380RNA splicing-IEA-  
GO:0042981regulation of apoptotic process-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA-  
GO:0016607nuclear speck-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24932901Etiopathogenesis of equinovarus foot malformations. (2014 Aug)Bacino CAEur J Med Genet
22980975Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. (2012 Sep 14)Imielinski MCell
20186023RBM5 as a putative tumor suppressor gene for lung cancer. (2010 Mar)Sutherland LCJ Thorac Oncol