Gene: SLC10A3

8273
DXS253E|P3
solute carrier family 10 member 3
protein-coding
Xq28
Ensembl:ENSG00000126903 MIM:312090 Vega:OTTHUMG00000013369 UniprotKB:P09131
NG_013261.2
PubMed
0   ANCO-SNPs
AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC52A20.841
TMEM2140.817
APEX20.811
NUCB10.806
FLII0.804
UNC45A0.802
AP5Z10.802
P4HB0.801
E2F40.799
GAK0.797

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.55
OR4F29-0.527
MYH2-0.255
MYL1-0.242
MTRNR2L6-0.23
MTRNR2L9-0.23
AMPD1-0.203
MYLPF-0.201
DIAPH3-0.19
KLRC2-0.188

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of SLC10A3 mRNA29067470
D000082AcetaminophenAcetaminophen affects the expression of SLC10A3 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 affects the expression of SLC10A3 protein20106945
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of SLC10A3 mRNA21298039
C006780bisphenol Abisphenol A results in decreased expression of SLC10A3 mRNA25181051
C018021cobaltous chloridecobaltous chloride results in decreased expression of SLC10A3 mRNA24386269
D003976DiazinonDiazinon results in increased methylation of SLC10A3 gene22964155
D004041Dietary FatsDietary Fats results in decreased expression of SLC10A3 mRNA18042831
C419708gefitinib[gefitinib co-treated with naphthalene] affects the expression of SLC10A3 mRNA20935109
C492448ICG 001ICG 001 results in increased expression of SLC10A3 mRNA26191083
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of SLC10A3 mRNA"25554681|2562005
C031721naphthalene[gefitinib co-treated with naphthalene] affects the expression of SLC10A3 mRNA20935109
D000073878Palm OilPalm Oil results in decreased expression of SLC10A3 mRNA18042831
D010936Plant ExtractsPlant Extracts results in decreased expression of SLC10A3 mRNA23557933
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of SLC10A3 mRNA22714537
C513428pyrachlostrobinpyrachlostrobin results in increased expression of SLC10A3 mRNA27029645
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SLC10A3 mRNA21570461
D014520UrethaneUrethane results in increased expression of SLC10A3 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of SLC10A3 mRNA25979313
D014635Valproic AcidValproic Acid affects the expression of SLC10A3 mRNA17292431
D024483Vitamin K 3Vitamin K 3 affects the expression of SLC10A3 mRNA20044591
D015215ZidovudineZidovudine results in increased expression of SLC10A3 mRNA24292225

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005342organic acid transmembrane transporter activity-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0015721bile acid and bile salt transport-IEA-  
GO:0032526response to retinoic acid-IEA-  
GO:0055085transmembrane transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
21921471[Familial Wernicke's-like encephalopathy]. (2010 Nov)Miyajima HRinsho Shinkeigaku