Gene: SNN

8303
-
stannin
protein-coding
16p13.13
Ensembl:ENSG00000184602 MIM:603032 Vega:OTTHUMG00000090535 UniprotKB:O75324
NC_000016.10
PubMed
0   ANCO-SNPs
OD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.545e-1 (AD)  6.211e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg00022235chr16:11764847SNNPromoter4.992e-4Alcohol use disorders26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DCAF110.936
ARNT20.93
SMARCA20.928
SENP30.927
ABR0.926
CALM10.926
PIP4K2B0.925
GNB10.925
RAB1B0.925
TNPO20.923

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.795
OR4F29-0.769
TFPI2-0.366
BEST3-0.354
SLAMF6-0.346
HAS2-0.333
C9orf135-0.327
CD48-0.326
GZMK-0.325
KCNJ15-0.325

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SNN mRNA"19167446
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of SNN mRNA"18648102
D000082AcetaminophenAcetaminophen results in increased expression of SNN mRNA21420995
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of SNN mRNA21641981|2210060
D019386AlendronateAlendronate affects the expression of SNN mRNA16079270
C103303alitretinoinalitretinoin results in decreased expression of SNN mRNA16648578
D000643Ammonium ChlorideAmmonium Chloride affects the expression of SNN mRNA16483693
D001280AtrazineAtrazine results in decreased expression of SNN mRNA22378314
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of SNN mRNA26238291
D004958EstradiolEstradiol results in decreased expression of SNN mRNA19167446
C095105bexarotenebexarotene results in decreased expression of SNN mRNA16648578
C006780bisphenol Abisphenol A affects the expression of SNN mRNA21786754
C006780bisphenol Abisphenol A results in decreased expression of SNN mRNA12075121
C006780bisphenol Abisphenol A results in increased expression of SNN mRNA25181051
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in decreased expression of SNN mRNA17553608
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of SNN mRNA15336504
D000068579CelecoxibCelecoxib results in increased expression of SNN mRNA28201806
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SNN mRNA20938992
C018021cobaltous chloridecobaltous chloride results in decreased expression of SNN mRNA24386269
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SNN mRNA"19167446
D003471CuprizoneCuprizone results in decreased expression of SNN mRNA26577399
D016572CyclosporineCyclosporine results in decreased expression of SNN mRNA20106945|2163298
D004147DioxinsDioxins affects the expression of SNN mRNA20463971
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of SNN mRNA16079270
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of SNN mRNA17557909
D005038EthylnitrosoureaEthylnitrosourea results in increased expression of SNN mRNA15954086
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SNN mRNA20938992
D007213IndomethacinIndomethacin results in increased expression of SNN mRNA28201806
C544151jinfukangjinfukang results in increased expression of SNN mRNA27392435
C045463leflunomideleflunomide results in decreased expression of SNN mRNA28988120
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SNN mRNA20938992
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of SNN mRNA"26251327
C017096n-butoxyethanoln-butoxyethanol results in decreased expression of SNN mRNA19812364
D005996NitroglycerinNitroglycerin results in decreased expression of SNN mRNA12102619
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of SNN mRNA25729387
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of SNN mRNA20118188
C023036perfluorooctanoic acidPPARA promotes the reaction [perfluorooctanoic acid results in increased expression of SNN mRNA]20118188
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SNN mRNA19710929
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride affects the expression of SNN mRNA16079270
D012999SomanSoman results in decreased expression of SNN mRNA19281266
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of SNN mRNA25172293
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SNN mRNA21570461
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of SNN mRNA25729387
D019772TopotecanTopotecan results in increased expression of SNN mRNA25729387
D014212TretinoinTretinoin results in increased expression of SNN mRNA23724009
C012589trichostatin Atrichostatin A affects the expression of SNN mRNA28542535
C057693troglitazonetroglitazone results in increased expression of SNN mRNA28973697
D014520UrethaneUrethane results in increased expression of SNN mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of SNN mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of SNN mRNA22083351|2915479
D000068756ValsartanValsartan inhibits the reaction [AGT protein results in increased expression of SNN mRNA]19225232
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of SNN gene25560391
C025643vinclozolinvinclozolin results in decreased expression of SNN mRNA23034163
D014750VincristineVincristine results in increased expression of SNN mRNA23649840
C111237vorinostatvorinostat results in increased expression of SNN mRNA22083351

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0046872metal ion binding-IDA16246365  
GO ID GO Term Qualifier Evidence PubMed
GO:0009636response to toxic substance-TAS16246365  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IDA16246365  
GO:0005741mitochondrial outer membrane-IEA-  
GO:0016021integral component of membrane-IDA16246365  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26625401A Spiking Neural Network Methodology and System for Learning and Comparative Analysis of EEG Data From Healthy Versus Addiction Treated Versus Addiction Not Treated Subjects. (2016 Sep)Doborjeh MGIEEE Trans Biomed Eng