Gene: CASP7

840
CASP-7|CMH-1|ICE-LAP3|LICE2|MCH3
caspase 7
protein-coding
10q25.3
Ensembl:ENSG00000165806 MIM:601761 Vega:OTTHUMG00000019076 UniprotKB:P55210
NC_000010.11
PubMed|SNP Mapped
ND|AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.230e-2 (AD)  1.061e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs11196449chr10:113720823 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)
rs3124743chr10:113704412 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
BAG30.815
TNFRSF1A0.812
PALLD0.808
ABHD30.802
CSF10.795
ZC3HAV10.795
P4HA10.793
TGIF10.787
NFE2L20.773
YAP10.772

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC7A4-0.591
PPEF1-0.555
MYOZ3-0.535
GPR61-0.523
AGMAT-0.522
ABCC12-0.522
MYCNOS-0.519
ZSCAN1-0.517
AARD-0.516
CRHBP-0.511

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB03384FicaSmall MoleculeExperimentalTarget
DB05408EmricasanSmall MoleculeInvestigationalTarget
ID Drug Name Action PubMed
C55281910-(octyloxy)decyl-2-(trimethylammonium)ethyl phosphate10-(octyloxy)decyl-2-(trimethylammonium)ethyl phosphate results in increased cleavage of CASP7 protein23001822
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased cleavage of CASP7 protein"24515801|2603571
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"Glutathione inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased cleavage of CASP7 protein]"24515801
C50489712-(3-adamantan-1-ylureido)dodecanoic acid12-(3-adamantan-1-ylureido)dodecanoic acid results in decreased expression of CASP7 mRNA19435785
C5822861-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP7 protein26208482
C5822861-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP7 protein]26208482
C5822861-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea"4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP7 protein]"26208482
C0364231-aminomethylphosphonic acid[1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased cleavage of and results in increased activity of CASP7 protein26006246
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether affects the expression of CASP7 mRNA"27589474
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased cleavage of CASP7 protein]14688022
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]24157283
C0445652-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide results in increased cleavage of CASP7 protein16142332
C0700552,3',4,4',5-pentachlorobiphenyl"2,3',4,4',5-pentachlorobiphenyl affects the activity of CASP7 protein"19362103
C4408502,4,3',5'-tetramethoxystilbene"2,4,3',5'-tetramethoxystilbene results in increased activity of CASP7 protein"20490654
C5411322,4,4',5-tetrachlorobiphenyl"2,4,4',5-tetrachlorobiphenyl affects the activity of CASP7 protein"19362103
C0098282,4,5,2',5'-pentachlorobiphenyl"2,4,5,2',5'-pentachlorobiphenyl results in increased activity of CASP7 protein"21504788
C5614542,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide"[GNAQ gene mutant form results in increased susceptibility to [trametinib co-treated with 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide]] which results in increased cleavage of CASP7 protein"22733540
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased cleavage of CASP7 protein14688022
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased activity of CASP7 protein]14687664
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased activity of CASP7 protein16487511
C5066982,5-dimethylcelecoxib"2,5-dimethylcelecoxib results in increased activity of CASP7 protein"18485224
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of CASP7 mRNA"21346803
C0127962-butenal2-butenal results in increased activity of CASP7 protein23535401
C5264372-methoxy-3-O-sulfamoyl-17-cyanomethylestra-1,3,5(10)-triene"2-methoxy-3-O-sulfamoyl-17-cyanomethylestra-1,3,5(10)-triene results in increased activity of CASP7 protein"19846905
C0228302-methoxyestradiol2-methoxyestradiol results in increased expression of CASP7 protein modified form23967052
C0228302-methoxyestradiolarsenic trioxide promotes the reaction [2-methoxyestradiol results in increased expression of CASP7 protein modified form]23967052
C5264382-methoxyestradiol-3,17-O,O-bis(sulfamate)"2-methoxyestradiol-3,17-O,O-bis(sulfamate) results in increased activity of CASP7 protein"19846905
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP7 protein]26208482
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]21616090
C0188552-tert-butylhydroquinone2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]22275372
C0005885823-methoxy-6-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-2-amine"3-methoxy-6-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-2-amine results in increased activity of CASP7 protein"24471873
C0259463-methyladenine3-methyladenine promotes the reaction [usnic acid results in increased activity of CASP7 protein]25078063
C0259463-methyladenine3-methyladenine results in increased activity of CASP7 protein20371669
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of CASP7 mRNA"25380136
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased activity of CASP7 protein]14687664
C4756224-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine"4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP7 protein]"26208482
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased activity of CASP7 protein24525193
C0275764-hydroxy-2-nonenalRACK1 mutant form inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP7 protein]24525193
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of CASP7 mRNA19191707
C4988264-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in increased activity of CASP7 protein23707608
C4988264-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in increased cleavage of CASP7 protein23883479
C0415944-nonylphenol4-nonylphenol results in decreased expression of CASP7 mRNA27109770
C0757734-phenylbutyric acid4-phenylbutyric acid inhibits the reaction [Sertraline results in increased activity of CASP7 protein]24865413
C0757734-phenylbutyric acid4-phenylbutyric acid inhibits the reaction [usnic acid results in increased activity of CASP7 protein]25870318
C5551425-(3-chlorophenylamino)benzo(c)(2,6)naphthyridine-8-carboxylic acid"5-(3-chlorophenylamino)benzo(c)(2,6)naphthyridine-8-carboxylic acid results in increased activity of CASP7 protein"21174434
C5805985-OH-BDE-475-OH-BDE-47 results in decreased expression of CASP7 mRNA27589474
C5715326-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in increased cleavage of CASP7 protein25316768
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Camptothecin results in increased activity of CASP7 protein]"24726431
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide promotes the reaction [Camptothecin results in increased activity of CASP7 protein]"24726431
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased activity of CASP7 protein]"17942326
C5319376-O-angeloylenolin6-O-angeloylenolin results in increased cleavage of CASP7 protein21192922
C5591457-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine"7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine results in increased activity of CASP7 protein"21417417
C0030017-ketocholesterol7-ketocholesterol results in increased activity of CASP7 protein24650663
C0030017-ketocholesterolSerotonin inhibits the reaction [7-ketocholesterol results in increased activity of CASP7 protein]24650663
C501332ABT-737ABT-737 results in increased activity of CASP7 protein20038611
D000082AcetaminophenAcetaminophen results in decreased activity of CASP7 protein24912781
D000082AcetaminophenAcetaminophen affects the expression of CASP7 mRNA17562736
C099158acetyl-aspartyl-glutamyl-valyl-aspartalacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cucurbitacin E results in increased cleavage of CASP7 protein]27106530
C099158acetyl-aspartyl-glutamyl-valyl-aspartalacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Mustard Gas results in increased cleavage of CASP7 protein]12482751
C099158acetyl-aspartyl-glutamyl-valyl-aspartalacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]24704558
D000111AcetylcysteineAcetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]25824409
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of and results in increased cleavage of CASP7 protein]"17136323
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]19771260
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenite results in increased activity of CASP7 protein]22260869
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP7 protein]"28087840
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of CASP7 protein]27106530
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Dopamine results in increased activity of and results in increased cleavage of CASP7 protein]17136323
D000111AcetylcysteineAcetylcysteine inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]21843585
D000111AcetylcysteineAcetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP7 protein]20594983
D000111AcetylcysteineAcetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP7 protein]24998639
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein]17136323
D000111AcetylcysteineAcetylcysteine inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]28161410
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP7 protein]17136323
D000111AcetylcysteineAcetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP7 protein]27539140
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]24157283
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP7 protein]22909951
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP7 mRNA]21549813
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]21145380
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP7 protein]23405080
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]22085843
D000171Acrolein2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
D000171Acrolein2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
D000171AcroleinAcrolein results in increased activity of CASP7 protein15843039|1719679
D000171AcroleinAcrolein results in increased cleavage of CASP7 protein15843039
D000171Acroleinpyrazolanthrone inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
D000171AcroleinSB 203580 inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
D000171AcroleinU 0126 inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
D000171Acroleinwortmannin inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
D000171AcroleinAcrolein results in increased activity of CASP7 protein19596284
C512484AG-012986AG-012986 results in increased activity of CASP7 protein22095879
C430898AGN 194204[AGN 194204 co-treated with IGFBP3 protein] results in increased activity of CASP7 protein16000583
C430898AGN 194204AGN 194204 results in increased activity of CASP7 protein16000583
C031143AICA ribonucleotideAICA ribonucleotide inhibits the reaction [sunitinib results in increased cleavage of CASP7 protein]21906609
C103303alitretinoin[TO-901317 co-treated with alitretinoin] promotes the reaction [Palmitic Acid results in increased activity of CASP7 protein]17194744
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in decreased expression of CASP7 mRNA27732882
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP7 protein27732882
D013196DihydrotestosteroneDihydrotestosterone analog results in increased activity of CASP717303658
D024502alpha-Tocopherol"alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP7 protein]"29129777
D024502alpha-Tocopherolalpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]23042730
D024502alpha-Tocopherolalpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]23042730
C052036alpidemalpidem results in increased activity of CASP7 protein22700542
C052036alpidemPalmitic Acid promotes the reaction [alpidem results in increased activity of CASP7 protein]22700542
D006710HomocysteineHomocysteine results in increased activity of CASP7 protein21237187
D006710Homocysteinemecobalamin inhibits the reaction [Homocysteine results in increased activity of CASP7 protein]21237187
D0157614-Aminopyridine4-Aminopyridine results in increased activity of CASP7 protein24378259
D000638Amiodaronealpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]23042730
D000638Amiodaronealpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]23042730
D000638AmiodaroneAmiodarone results in increased activity of CASP7 protein23042730|2313554
D000638AmiodaroneTNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]23042730
D000638AmiodaroneAmiodarone results in increased expression of CASP7 mRNA24489787
D017311Amlodipine[Amlodipine co-treated with Topotecan] results in increased activity of CASP7 protein16516327
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CASP7 mRNA16483693
D000643Ammonium ChlorideAmmonium Chloride results in increased expression of CASP7 protein16483693
C540917anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione"anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione results in increased cleavage of CASP7 protein"19146838
C540917anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione"TP53 protein promotes the reaction [anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione results in increased cleavage of CASP7 protein]"19146838
D000880AnthraquinonesAnthraquinones analog results in increased cleavage of CASP7 protein19686834
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of CASP7 mRNA24449571
D047310ApigeninApigenin results in increased activity of CASP7 protein19647729
D047310ApigeninApigenin results in increased cleavage of CASP7 protein15486995
D001151ArsenicArsenic results in increased cleavage of CASP7 protein26385919
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]19771260
C006632arsenic trioxidearsenic trioxide promotes the reaction [2-methoxyestradiol results in increased expression of CASP7 protein modified form]23967052
C006632arsenic trioxidearsenic trioxide results in increased activity of CASP7 protein12181429|1288326
C006632arsenic trioxidearsenic trioxide results in increased cleavage of CASP7 protein12480548|1969527
C006632arsenic trioxide2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]24157283
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]24157283
C006632arsenic trioxidearsenic trioxide results in increased activity of CASP7 protein24157283
C006632arsenic trioxidearsenic trioxide results in increased cleavage of and results in increased activity of CASP7 protein15688020
C006632arsenic trioxideDDIT3 mutant form inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]24157283
C006632arsenic trioxideHSPA5 mutant form inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]24157283
C006632arsenic trioxidepyrazolanthrone inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]24157283
C006632arsenic trioxideTretinoin promotes the reaction [arsenic trioxide results in increased cleavage of CASP7 protein]15688020
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]21145380
C006632arsenic trioxidearsenic trioxide results in increased activity of CASP7 protein20937774|2114538
C006632arsenic trioxidebenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]20937774
C015001arseniteAcetylcysteine inhibits the reaction [arsenite results in increased activity of CASP7 protein]22260869
C015001arsenite[arsenite results in decreased activity of PARP1 protein] which results in decreased cleavage of and results in decreased activity of CASP7 protein22387748
C015001arsenitearsenite results in decreased cleavage of and results in decreased activity of CASP7 protein22387748
C015001arsenitearsenite results in increased activity of CASP7 protein22260869
C015001arsenitearsenite results in increased expression of CASP7 protein26677073
C015001arseniteTP53 mutant form inhibits the reaction [arsenite results in increased activity of CASP7 protein]22260869
C015001arsenitearsenite results in increased activity of CASP7 protein18316066
C000606252ARV-825ARV-825 results in increased activity of CASP7 protein26051217
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased activity of CASP7 protein"19783790
D001205Ascorbic AcidAscorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP7 protein]17301063
D001241AspirinAspirin results in increased cleavage of and results in increased activity of CASP7 protein15481331
C517975AZD 6244AZD 6244 results in increased cleavage of CASP7 protein17876044
C517975AZD 6244Doxorubicin promotes the reaction [AZD 6244 results in increased cleavage of CASP7 protein]17876044
C547126AZM551248AZM551248 results in decreased expression of CASP7 mRNA22323515
C040929bafilomycin A1bafilomycin A1 results in decreased activity of CASP7 protein25981168
C040929bafilomycin A1bafilomycin A1 results in increased activity of CASP7 protein20371669
C004456beauvericinbeauvericin results in increased activity of CASP7 protein25178661
D000069461Bendamustine HydrochlorideBendamustine Hydrochloride results in increased activity of CASP7 protein12948851
D000069461Bendamustine HydrochlorideCladribine promotes the reaction [Bendamustine Hydrochloride results in increased activity of CASP7 protein]12948851
D001546BentoniteBentonite inhibits the reaction [[HT-2 toxin co-treated with T-2 Toxin] results in increased expression of CASP7 mRNA]25296281
D001554BenzeneBenzene affects the activity of CASP7 protein22960397
C026487benzo(e)pyrenebenzo(e)pyrene results in increased activity of CASP7 protein18586875|1995963
C026487benzo(e)pyreneGenistein inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein]19959636
C026487benzo(e)pyreneMemantine inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein]19959636
C026487benzo(e)pyreneresveratrol inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein]19959636
C026487benzo(e)pyrenebenzo(e)pyrene results in increased activity of CASP7 protein19899995
D053119BenzophenanthridinesBenzophenanthridines analog results in increased activity of CASP7 protein23117580
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CASP7 mRNA24239969
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CASP7 protein22581694
D001564Benzo(a)pyreneCYP1B1 mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP7 mRNA]24239969
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased activity of CASP7 protein19874837
D001564Benzo(a)pyreneChlordan promotes the reaction [Benzo(a)pyrene results in increased activity of CASP7 protein]19874837
D001564Benzo(a)pyreneGJA1 mutant form promotes the reaction [Benzo(a)pyrene results in increased activity of CASP7 protein]19874837
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of CASP7 protein"21983885
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"BAX protein affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of CASP7 protein]"21983885
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"TP53 protein affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of CASP7 protein]"21983885
C110772benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Endosulfan results in increased activity of CASP7 protein]20361990
C403754benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]18056177
C403754benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [rubimaillin results in increased activity of CASP7 protein]19716835
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP7 protein19139269
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [NCQ 344 results in increased activity of CASP7 protein]10996300
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [NCQ 436 results in increased activity of CASP7 protein]10996300
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein]21035945
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[resveratrol co-treated with clofarabine] promotes the reaction [MCL1 mutant form results in increased activity of CASP7 protein]]24924397
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[resveratrol co-treated with clofarabine] results in increased activity of CASP7 protein]24924397
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]20937774
C103712benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethanebenzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Nickel results in increased expression of CASP7 protein modified form]28330870
D004958EstradiolEstradiol affects the expression of CASP7 mRNA14699072
D004958Estradiol[Estradiol binds to ESR2 protein] which results in increased expression of CASP7 mRNA20404318
D004958Estradiol[Estradiol co-treated with EGF protein] results in increased expression of CASP7 mRNA24758408
D004958EstradiolEstradiol promotes the reaction [ESR2 protein affects the expression of CASP7 mRNA]20404318
D004958EstradiolEstradiol results in decreased expression of CASP7 mRNA23373633
D004958Estradiol[resveratrol co-treated with Estradiol] results in increased activity of CASP7 protein24894866
C002070betulinic acidbetulinic acid results in increased activity of CASP7 protein22260869
C006780bisphenol Abisphenol A results in decreased expression of CASP7 protein21277958
C006780bisphenol Abisphenol A results in increased expression of CASP7 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CASP7 mRNA28628672
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of CASP7 mRNA22434021
C557045BO-1051ATM protein promotes the reaction [BO-1051 results in increased cleavage of CASP7 protein]21184746
C557045BO-1051BECN1 protein inhibits the reaction [BO-1051 results in increased cleavage of CASP7 protein]21184746
C557045BO-1051BO-1051 results in increased cleavage of CASP7 protein21184746
D000069286Bortezomib[Bortezomib co-treated with trichostatin A] results in increased cleavage of and results in increased activity of CASP7 protein16904634
D000069286BortezomibBortezomib results in increased activity of CASP7 protein18342500|1853401
D000069286BortezomibBortezomib results in increased cleavage of and results in increased activity of CASP7 protein16024631
D000069286BortezomibBortezomib results in increased cleavage of CASP7 protein16617327
D000069286BortezomibSCIO-469 promotes the reaction [Bortezomib results in increased cleavage of CASP7 protein]16617327
C089020brassininbrassinin analog results in increased activity of CASP7 protein24747292
D002065BuspironeBuspirone results in decreased expression of CASP7 mRNA24136188
D019328Buthionine Sulfoximine"Buthionine Sulfoximine promotes the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate affects the cleavage of CASP7 protein]"20962031
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]21843585
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [[TNF protein co-treated with Cycloheximide] results in increased activity of CASP7 protein]15950244
D020122tert-ButylhydroperoxidePlant Extracts inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP7 protein]27050144
D020122tert-ButylhydroperoxideQuercetin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP7 protein]27050144
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased cleavage of CASP7 protein27050144
D002087ButyratesButyrates results in increased activity of CASP7 protein15213223
D002087ButyratesGSN protein inhibits the reaction [Butyrates results in increased activity of CASP7 protein]15213223
D002104CadmiumCadmium results in decreased expression of CASP7 mRNA22768170
D002104CadmiumCadmium results in increased activity of CASP7 protein20600546
D002104CadmiumCadmium results in increased activity of CASP7 protein16478757|1846310
D002104CadmiumCadmium results in increased cleavage of CASP7 protein27658547
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of CASP7 mRNA12160620|1942679
D019256Cadmium ChlorideCadmium Chloride results in increased activity of CASP7 protein17943274
D019256Cadmium ChlorideCadmium Chloride results in increased cleavage of CASP7 protein25157103
D019256Cadmium ChlorideACHE mutant form inhibits the reaction [Cadmium Chloride results in increased activity of CASP7 protein]26026611
D019256Cadmium ChlorideAPP mutant form inhibits the reaction [Cadmium Chloride results in increased activity of CASP7 protein]26026611
D019256Cadmium Chloride[Cadmium Chloride co-treated with Potassium Dichromate] results in increased expression of CASP7 mRNA25409916
D019256Cadmium ChlorideCadmium Chloride results in increased activity of CASP7 protein26026611
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CASP7 mRNA25409916
D019256Cadmium ChlorideCHRM1 mutant form promotes the reaction [Cadmium Chloride results in increased activity of CASP7 protein]26026611
D019256Cadmium ChlorideGSK3B mutant form inhibits the reaction [Cadmium Chloride results in increased activity of CASP7 protein]26026611
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP7 protein]23405080
D019256Cadmium ChlorideCadmium Chloride results in increased activity of CASP7 protein16478757
D019256Cadmium ChlorideCadmium Chloride results in increased cleavage of CASP7 protein23405080
D019256Cadmium Chloridepyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP7 protein]23405080
D019187Cadmium CompoundsCadmium Compounds results in increased activity of CASP7 protein25684395
C037123cadmium sulfate2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased activity of CASP7 protein]14687664
C037123cadmium sulfate4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased activity of CASP7 protein]14687664
C037123cadmium sulfatecadmium sulfate results in increased activity of CASP7 protein14687664
C037123cadmium sulfateN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [cadmium sulfate results in increased activity of CASP7 protein]14687664
C034939cadmium sulfidecadmium sulfide results in decreased expression of CASP7 mRNA27866839
D000001CalcimycinCalcimycin results in increased activity of CASP7 protein19139269
D002166Camptothecin"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Camptothecin results in increased activity of CASP7 protein]"24726431
D002166Camptothecin"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide promotes the reaction [Camptothecin results in increased activity of CASP7 protein]"24726431
D002166CamptothecinCamptothecin results in increased activity of CASP7 protein22302033|2472643
D002166Camptothecinpalbociclib inhibits the reaction [Camptothecin results in increased activity of CASP7 protein]22302033
D002211Capsaicin[Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP7 protein19939880
D002211CapsaicinCapsaicin results in increased activity of CASP7 protein19139269|1969925
D002248Carbon MonoxideCarbon Monoxide results in increased activity of CASP7 protein25562542
C111238carboxycinnamic acid bishydroxamidecarboxycinnamic acid bishydroxamide results in increased cleavage of CASP7 protein15897598
C054133casticincasticin results in increased expression of CASP7 protein27862857
D002392CatechinCatechin inhibits the reaction [catechol results in increased activity of CASP7 protein]20347921
D002392CatechinCatechin results in increased expression of CASP7 mRNA23706674
C034221catecholCatechin inhibits the reaction [catechol results in increased activity of CASP7 protein]20347921
C034221catecholcatechol results in increased activity of CASP7 protein20347921
C034221catecholMemantine inhibits the reaction [catechol results in increased activity of CASP7 protein]20347921
D000068579CelecoxibCelecoxib analog affects the activity of CASP7 protein18485224
D000068579CelecoxibCelecoxib results in increased activity of CASP718202791
D000068579CelecoxibCelecoxib results in increased activity of CASP7 protein18485224
D000068579CelecoxibCelecoxib results in increased cleavage of and results in increased activity of CASP7 protein15572759
D000068579CelecoxibTNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP7 protein]15572759
D002518CeramidesCeramides results in increased expression of CASP723495037
D002518Ceramides[fumonisin B1 results in decreased chemical synthesis of Ceramides] which results in decreased expression of CASP7 protein modified form25195822
D002518Ceramides[UGCG protein results in decreased abundance of Ceramides] which results in decreased expression of CASP7 protein modified form25195822
C030583ceric oxideceric oxide analog affects the expression of CASP7 mRNA22960666
C016299chelerythrinechelerythrine results in increased cleavage of CASP7 protein26124276
D002706ChlordanChlordan promotes the reaction [Benzo(a)pyrene results in increased activity of CASP7 protein]19874837
C006972chloroacetic acidchloroacetic acid results in increased cleavage of and results in increased activity of CASP7 protein23103613
C006972chloroacetic acidSB 203580 inhibits the reaction [chloroacetic acid results in increased activity of CASP7 protein]23103613
D017338CladribineCladribine promotes the reaction [Bendamustine Hydrochloride results in increased activity of CASP7 protein]12948851
D017338CladribineCladribine results in increased activity of CASP7 protein12948851
D002738ChloroquineChloroquine promotes the reaction [usnic acid results in increased activity of CASP7 protein]25078063
D004390ChlorpyrifosChlorpyrifos results in increased activity of CASP7 protein26210949
D004390Chlorpyrifos[nickel chloride co-treated with Chlorpyrifos] affects the expression of CASP7 mRNA21496282
D004390ChlorpyrifosChlorpyrifos results in increased activity of CASP7 protein19167454
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CASP7 mRNA20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CASP7 gene20938992
C529269cholix toxin, Vibrio cholerae"Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP7 protein]"28087840
C529269cholix toxin, Vibrio cholerae"[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP7 protein"28087840
C074702chromium hexavalent ionAscorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP7 protein]17301063
C074702chromium hexavalent ionchromium hexavalent ion results in increased activity of CASP7 protein15831465
C074702chromium hexavalent ionchromium hexavalent ion results in increased cleavage of CASP7 protein17301063
C074702chromium hexavalent ionMLH1 protein affects the reaction [chromium hexavalent ion results in increased activity of CASP7 protein]15831465
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of CASP7 mRNA28472532
C045645cilostazolcilostazol inhibits the reaction [Nitroprusside results in increased activity of CASP7 protein]18311796
D002927CimetidineCimetidine results in increased activity of CASP7 protein17273750
C068329clofarabineBCL2L1 protein affects the reaction [[clofarabine co-treated with resveratrol] results in increased activity of CASP7 protein]25408576
C068329clofarabinebenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[resveratrol co-treated with clofarabine] promotes the reaction [MCL1 mutant form results in increased activity of CASP7 protein]]24924397
C068329clofarabinebenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[resveratrol co-treated with clofarabine] results in increased activity of CASP7 protein]24924397
C068329clofarabine[clofarabine co-treated with resveratrol] promotes the reaction [BCL2L1 mutant form results in increased activity of CASP7 protein]25408576
C068329clofarabine[clofarabine co-treated with resveratrol] results in increased activity of CASP7 protein25408576
C068329clofarabine[resveratrol co-treated with clofarabine] promotes the reaction [MCL1 mutant form results in increased activity of CASP7 protein]24924397
C068329clofarabine[resveratrol co-treated with clofarabine] results in increased activity of CASP7 protein24924397
D002997ClomipramineClomipramine results in increased activity of CASP7 protein22700542
D002997ClomipraminePalmitic Acid promotes the reaction [Clomipramine results in increased activity of CASP7 protein]22700542
D003024ClozapineClozapine results in increased activity of CASP7 protein22700542
D003024ClozapinePalmitic Acid promotes the reaction [Clozapine results in increased activity of CASP7 protein]22700542
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased activity of CASP7 protein]18819247
C007095cobaltiprotoporphyrin[cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased activity of CASP7 protein]] which results in decreased cleavage of PARP1 protein18819247
C018021cobaltous chloridecobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of CASP7 protein]22172632
C018021cobaltous chloridecobaltous chloride results in increased cleavage of CASP7 protein22172632
C018021cobaltous chloridecobaltous chloride results in increased expression of CASP7 mRNA19376846
C018021cobaltous chloridenickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of CASP7 protein]22172632
D003300Copper[NSC 689534 binds to Copper] which results in increased activity of CASP7 protein20971185
D003300CopperCopper affects the expression of CASP7 mRNA23825565
D003300CopperCopper results in increased activity of CASP7 protein16672322
D003300Copperpyrazolanthrone inhibits the reaction [Copper results in increased activity of CASP7 protein]16672322
D003300Copperquinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [Copper results in increased activity of CASP7 protein]16672322
D003300CopperSB 203580 inhibits the reaction [Copper results in increased activity of CASP7 protein]16672322
D003300CopperU 0126 inhibits the reaction [Copper results in increased activity of CASP7 protein]16672322
D003300CopperAcetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]22085843
D003300Copper[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein22085843
D019327Copper SulfateCopper Sulfate results in increased activity of CASP7 protein21765606
D019327Copper SulfateGW0742 inhibits the reaction [Copper Sulfate results in increased activity of CASP7 protein]21765606
C058120cordycepinacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]24704558
C058120cordycepinADORA2A mutant form inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]24704558
C058120cordycepincordycepin results in increased cleavage of CASP7 protein24704558
C058120cordycepinpifithrin inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]24704558
C058120cordycepinTP53 mutant form inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]24704558
C058120cordycepinZM 241385 inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]24704558
D003367CotinineCotinine inhibits the reaction [Doxorubicin results in increased activity of CASP7 protein]22687995
D003375CoumestrolCoumestrol results in increased expression of CASP7 protein19165469
C551994crizotinibcrizotinib results in increased activity of CASP7 protein23707608
C037886cryptotanshinonecryptotanshinone results in increased activity of CASP7 protein26564229
C102326cucurbitacin Eacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cucurbitacin E results in increased cleavage of CASP7 protein]27106530
C102326cucurbitacin EAcetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of CASP7 protein]27106530
C102326cucurbitacin Ecucurbitacin E results in increased cleavage of CASP7 protein27106530
C038106cucurbitacin Icucurbitacin I results in increased cleavage of CASP7 protein24858077
C029892cupric chloridebenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein]21035945
C029892cupric chloride[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein21035945
C029892cupric chloride[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein20920558
C029892cupric chlorideMAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]20920558
C029892cupric chloridepyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein]20920558
D003474Curcumin[Curcumin co-treated with Sirolimus] results in increased activity of CASP7 protein19373661
D003474CurcuminCurcumin results in decreased expression of CASP7 mRNA16101141
D003474CurcuminCurcumin results in increased cleavage of and results in increased activity of CASP7 protein16023083
D003513CycloheximideCycloheximide inhibits the reaction [Tretinoin results in increased expression of CASP7 mRNA]16166294
D003513CycloheximideCycloheximide promotes the reaction [FAS protein results in increased activity of CASP7 protein]12760867
D003513CycloheximideButylated Hydroxyanisole inhibits the reaction [[TNF protein co-treated with Cycloheximide] results in increased activity of CASP7 protein]15950244
D003513CycloheximideMasoprocol inhibits the reaction [[TNF protein co-treated with Cycloheximide] results in increased activity of CASP7 protein]15950244
D003513Cycloheximide[TNF protein co-treated with Cycloheximide] results in increased activity of CASP7 protein15950244
D016572CyclosporineCyclosporine results in increased activity of CASP7 protein22700542
D016572CyclosporineCyclosporine results in increased expression of CASP7 mRNA20106945
D016572CyclosporinePalmitic Acid promotes the reaction [Cyclosporine results in increased activity of CASP7 protein]22700542
C089595cylindrospermopsincylindrospermopsin results in decreased expression of CASP7 mRNA23726867
C017160cypermethrincypermethrin results in increased expression of CASP7 mRNA27704156
C017160cypermethrincypermethrin results in increased cleavage of and results in increased activity of CASP7 protein22048644
C017160cypermethrinHBEGF protein inhibits the reaction [cypermethrin results in increased cleavage of and results in increased activity of CASP7 protein]22048644
C093628cyproconazole[cyproconazole co-treated with epoxiconazole] results in increased expression of CASP7 mRNA29038839
D003609Dactinomycin[Dactinomycin co-treated with TNFSF10 protein] results in increased activity of CASP7 protein17707539
D003609DactinomycinDactinomycin promotes the reaction [TNF results in increased activity of CASP7 protein]16492401
D003609DactinomycinDactinomycin results in decreased expression of CASP7 mRNA16001973
D003609Dactinomycin[TNF co-treated with Dactinomycin] results in increased activity of CASP7 protein16492401
D003609Dactinomycin[TNF protein co-treated with Dactinomycin] results in increased activity of CASP7 protein21496118
C515055darinaparsindarinaparsin results in increased activity of CASP7 protein23426167
D000069439DasatinibDasatinib results in increased cleavage of CASP7 protein18550857
D003634DDTDDT results in increased activity of CASP7 protein15603917
D003634DDTSB 203580 inhibits the reaction [DDT results in increased activity of CASP7 protein]15603917
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased activity of CASP7 protein22485137
C014347decitabine[decitabine affects the methylation of CASP7 gene] which affects the expression of CASP7 protein18649362|1864936
C014347decitabine[decitabine co-treated with vorinostat] affects the expression of CASP7 mRNA17330099
C107676deguelindeguelin metabolite results in increased expression of CASP7 protein modified form19139008
C107676deguelindeguelin results in increased expression of CASP7 protein modified form19139008
C007262deoxynivalenoldeoxynivalenol results in increased activity of CASP7 protein27757495
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CASP7 mRNA28628672
D003907DexamethasoneDexamethasone inhibits the reaction [TGFB1 protein results in increased activity of CASP7 protein]15388240
D020927DexmedetomidineDexmedetomidine results in increased activity of CASP7 protein18724006
D016190CarboplatinCarboplatin results in increased activity of CASP7 protein22302033
D016190Carboplatinpalbociclib inhibits the reaction [Carboplatin results in increased activity of CASP7 protein]22302033
D003976DiazinonDiazinon affects the expression of CASP7 mRNA22546817
C016366dibenzothiophenedibenzothiophene results in decreased expression of CASP7 mRNA23656968
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of CASP7 mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of CASP7 mRNA17361019
D002945Cisplatin[Cisplatin co-treated with CDKN1A protein] results in increased cleavage of CASP7 protein18483502
D002945Cisplatin[Cisplatin co-treated with CDKN1A protein] results in increased expression of CASP7 mRNA18483502
D002945Cisplatin[Cisplatin co-treated with fisetin] promotes the reaction [CASP9 protein results in increased cleavage of CASP7 protein]21216935
D002945CisplatinCisplatin promotes the reaction [Metformin results in increased activity of CASP7 protein]21388661
D002945CisplatinCisplatin results in increased activity of CASP7 protein20654585|2142039
D002945CisplatinCisplatin results in increased expression of CASP7 mRNA18483502|2759478
D002945CisplatinTINAG inhibits the reaction [Cisplatin results in increased activity of CASP7 protein]21795690
D002945Cisplatin[Cisplatin co-treated with vinorelbine] results in decreased expression of CASP7 mRNA21544650
D002945CisplatinPAK2 protein modified form promotes the reaction [Cisplatin results in increased activity of CASP7 protein]21499899
D002945CisplatinCisplatin results in increased cleavage of and results in increased activity of CASP7 protein24973089
D002945CisplatinCTNNA1 gene affects the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP7 protein]24973089
D004026DieldrinDieldrin affects the expression of CASP7 mRNA22546817
D004026Dieldrin[Lindane co-treated with Dieldrin] results in increased activity of CASP7 protein20036686
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased activity of CASP7 protein21864672
D004052DiethylnitrosamineCLOCK protein promotes the reaction [Diethylnitrosamine results in increased activity of CASP7 protein]21167249
D004052DiethylnitrosamineDiethylnitrosamine results in increased activity of CASP7 protein21167249
C012906dihydrocapsaicindihydrocapsaicin results in increased activity of CASP7 protein19139269
C472036dihydromyricetinAcetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP7 protein]27539140
C472036dihydromyricetindihydromyricetin results in increased cleavage of CASP7 protein27539140
C472036dihydromyricetinpyrazolanthrone promotes the reaction [dihydromyricetin results in increased cleavage of CASP7 protein]27539140
C472036dihydromyricetinU 0126 promotes the reaction [dihydromyricetin results in increased cleavage of CASP7 protein]27539140
D008559MemantineMemantine inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein]19959636
D008559MemantineMemantine inhibits the reaction [catechol results in increased activity of CASP7 protein]20347921
D004128DimethylnitrosamineDimethylnitrosamine results in decreased expression of CASP7 mRNA25380136
C024629dimethyl phthalatedimethyl phthalate affects the expression of CASP7 mRNA26924002
C010715di-n-octyl phthalatedi-n-octyl phthalate results in decreased expression of CASP7 protein29128616
D004145DiosminDiosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP7 protein]23665045
D004176DipyridamoleDipyridamole results in increased activity of CASP7 protein22700542
D004176DipyridamolePalmitic Acid promotes the reaction [Dipyridamole results in increased activity of CASP7 protein]22700542
D004221DisulfiramDisulfiram results in increased activity of CASP7 protein17026967
C521792DMU-212DMU-212 results in increased activity of CASP7 protein24055891
D004281Docosahexaenoic Acids[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased activity of CASP7 protein16963249
D007980LevodopaLevodopa inhibits the reaction [Oxidopamine results in increased expression of CASP7 mRNA]25129099
D004298DopamineAcetylcysteine inhibits the reaction [Dopamine results in increased activity of and results in increased cleavage of CASP7 protein]17136323
D004298DopamineDopamine results in increased activity of and results in increased cleavage of CASP7 protein17136323
D004298DopamineDopamine results in increased activity of CASP7 protein19410601
D004317DoxorubicinAcetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]25824409
D004317DoxorubicinCotinine inhibits the reaction [Doxorubicin results in increased activity of CASP7 protein]22687995
D004317DoxorubicinDoxorubicin affects the activity of CASP7 protein15870702
D004317Doxorubicin[Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP7 protein16168113
D004317DoxorubicinDoxorubicin inhibits the reaction [Thapsigargin results in increased activity of and results in increased cleavage of CASP7 protein]16298333
D004317DoxorubicinDoxorubicin results in increased activity of and results in increased cleavage of CASP7 protein16298333
D004317DoxorubicinDoxorubicin results in increased activity of CASP7 protein11502879|1910663
D004317DoxorubicinDoxorubicin results in increased cleavage of and results in increased activity of CASP7 protein16024631
D004317DoxorubicinDoxorubicin results in increased cleavage of CASP7 protein17653088|2620848
D004317DoxorubicinDoxorubicin results in increased expression of CASP7 mRNA16001973|1670569
D004317Doxorubicin[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein25824409
D004317DoxorubicinGPX1 protein inhibits the reaction [Doxorubicin results in increased activity of CASP7 protein]11502879
D004317Doxorubicinpalbociclib inhibits the reaction [Doxorubicin results in increased activity of CASP7 protein]22302033
D004317DoxorubicinPI103 promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]23300809
D004317DoxorubicinTNFSF10 protein promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]19106633
D004317DoxorubicinDoxorubicin promotes the reaction [AZD 6244 results in increased cleavage of CASP7 protein]17876044
D004317DoxorubicinDoxorubicin results in increased activity of CASP7 protein27155237|2725538
D004317DoxorubicinPARP1 gene mutant form promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]15861398
D004317Doxorubicin[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]15861398
D004317DoxorubicinDoxorubicin results in increased activity of CASP7 protein27255381
C118667dronedaronedronedarone results in increased activity of CASP7 protein23135547
C034192ellipticineAcetylcysteine inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]21843585
C034192ellipticineButylated Hydroxyanisole inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]21843585
C034192ellipticineellipticine results in increased cleavage of and results in increased activity of CASP7 protein21843585
C034192ellipticinepyrazolanthrone inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]21843585
C034192ellipticineU 0126 inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]21843585
D004726Endosulfanbenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Endosulfan results in increased activity of CASP7 protein]20361990
D004726EndosulfanEndosulfan results in increased activity of CASP7 protein20361990
C109476epoxiconazole[cyproconazole co-treated with epoxiconazole] results in increased expression of CASP7 mRNA29038839
D060754EquolEquol results in increased cleavage of CASP7 protein18973749
D004970EstroneEstrone results in increased activity of CASP7 protein22700542
D004970EstronePalmitic Acid promotes the reaction [Estrone results in increased activity of CASP7 protein]22700542
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CASP7 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CASP7 mRNA17557909
C002994ethylene dimethanesulfonateethylene dimethanesulfonate results in decreased expression of CASP7 mRNA22711419
D017308EtodolacEtodolac results in increased activity of CASP7 protein16046235
D005047Etoposidebenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]18056177
D005047EtoposideEtoposide results in increased activity of CASP7 protein18056177|2029954
D005047Etoposidepalbociclib inhibits the reaction [Etoposide results in increased activity of CASP7 protein]22302033
D005047Etoposidepifithrin promotes the reaction [Etoposide results in increased activity of CASP7 protein]26259609
D005047Etoposide[STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposide18649362
D005047EtoposideTetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP7 protein]20299546
D005047EtoposideTP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP7 protein]21801448
D005047Etoposide2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]22275372
D005047EtoposideEtoposide results in increased activity of CASP7 protein22275372
C038628fipexidefipexide results in increased activity of CASP7 protein22700542
C038628fipexidePalmitic Acid promotes the reaction [fipexide results in increased activity of CASP7 protein]22700542
C082360fipronilfipronil results in increased activity of CASP7 protein17084830
C017875fisetin[Cisplatin co-treated with fisetin] promotes the reaction [CASP9 protein results in increased cleavage of CASP7 protein]21216935
C017875fisetinfisetin promotes the reaction [CASP9 protein results in increased cleavage of CASP7 protein]21216935
D044950Flavanones2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]21616090
D044950FlavanonesCDKN1A gene mutant form promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]21616090
D044950FlavanonesFlavanones results in increased cleavage of CASP7 protein21616090
D044950FlavanonesPI103 promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]21616090
D044950FlavanonesTP53 gene mutant form promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]21616090
D044950FlavanonesU 0126 promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]21616090
D044948FlavonolsFlavonols results in increased activity of and results in increased cleavage of CASP7 protein28235426
D005424FlecainideFlecainide results in increased activity of CASP7 protein22700542
D005424FlecainidePalmitic Acid promotes the reaction [Flecainide results in increased activity of CASP7 protein]22700542
C024352fludarabine[LAQ824 co-treated with fludarabine] results in increased activity of CASP7 protein18852132
D005445FlunitrazepamCYP3A4 protein affects the reaction [Flunitrazepam results in increased activity of CASP7 protein]19005028
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased activity of CASP7 protein23665045
D0150732-AcetylaminofluoreneDiosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of CASP7 protein]23665045
D005472Fluorouracil[Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP7 protein16168113
D005472FluorouracilFluorouracil results in increased cleavage of CASP7 protein26544897
D005473FluoxetineFluoxetine results in increased activity of CASP7 protein22700542
D005473FluoxetinePalmitic Acid promotes the reaction [Fluoxetine results in increased activity of CASP7 protein]22700542
D005485FlutamideFlutamide results in increased expression of CASP7 mRNA24136188
D016666FluvoxamineFluvoxamine results in increased activity of CASP7 protein22700542
D016666FluvoxaminePalmitic Acid promotes the reaction [Fluvoxamine results in increased activity of CASP7 protein]22700542
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CASP7 mRNA20938992
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CASP7 gene20938992
C025164fucoxanthinAcetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP7 protein]20594983
C025164fucoxanthinfucoxanthin results in increased cleavage of CASP7 protein20594983
C056933fumonisin B1[fumonisin B1 results in decreased chemical synthesis of Ceramides] which results in decreased expression of CASP7 protein modified form25195822
D005659Fungicides, Industrial"Fungicides, Industrial results in increased activity of CASP7 protein"24719846
D005688Galactosamine[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP7 protein21146893
D005688GalactosamineUrsodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP7 protein]21146893
D005707Gallic AcidGallic Acid results in increased activity of CASP7 protein24726691
C052659gambogic acidAcetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]25824409
C052659gambogic acid[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein25824409
C001277geldanamycinAcetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP7 protein]24998639
C001277geldanamycingeldanamycin results in increased activity of CASP7 protein24998639
D019833GenisteinGenistein inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein]19959636
D005978Glutathione"Glutathione inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased cleavage of CASP7 protein]"24515801
D005978GlutathioneGlutathione inhibits the reaction [NR4A1 protein affects the cleavage of CASP7 protein]24515801
C071834glycidamideglycidamide results in decreased expression of CASP7 mRNA17822822
C010974glyphosate[glyphosate co-treated with Herbicides] results in increased activity of CASP7 protein19539684
C010974glyphosateglyphosate results in increased activity of CASP7 protein19105591
C010974glyphosate[Surface-Active Agents co-treated with glyphosate] results in increased activity of CASP7 protein23099315
D006046GoldGold analog results in increased cleavage of CASP7 protein26551149
D006072GossypolGossypol results in increased activity of CASP7 protein19825521
D006072Gossypol[zoledronic acid co-treated with Gossypol] results in increased activity of CASP7 protein19825521
C554645GSK525762AGSK525762A results in increased activity of CASP7 protein26911376
D006146GuanidinesGuanidines analog results in increased cleavage of CASP7 protein23147571
C479979GW0742GW0742 inhibits the reaction [Copper Sulfate results in increased activity of CASP7 protein]21765606
C500810GW8510GW8510 inhibits the reaction [SNCA protein results in increased activity of CASP7 protein]24989254
D006540Herbicides[glyphosate co-treated with Herbicides] results in increased activity of CASP7 protein19539684
D006540HerbicidesHerbicides results in increased activity of CASP7 protein19105591|2233734
D006540Herbicides"insecticidal crystal protein, Bacillus Thuringiensis inhibits the reaction [Herbicides results in increased activity of CASP7 protein]"22337346
D006575Heterocyclic Compounds, 3-Ring"Heterocyclic Compounds, 3-Ring results in increased activity of CASP7 protein"21500194
C089796hexabromocyclododecanehexabromocyclododecane results in increased activity of CASP7 protein22485137
D017313FenretinideFenretinide results in increased activity of CASP7 protein16675469|2002296
D012701SerotoninSerotonin inhibits the reaction [7-ketocholesterol results in increased activity of CASP7 protein]24650663
C012351HT-2 toxinBentonite inhibits the reaction [[HT-2 toxin co-treated with T-2 Toxin] results in increased expression of CASP7 mRNA]25296281
C012351HT-2 toxin[HT-2 toxin co-treated with T-2 Toxin] results in increased expression of CASP7 mRNA25296281
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of CASP7 protein19706323
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of CASP7 protein16249675
D006861Hydrogen PeroxideIsoflurane inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP7 protein]16249675
C031927hydroquinonehydroquinone results in decreased activity of CASP7 protein22960397
C031927hydroquinonehydroquinone results in increased cleavage of CASP7 protein19064679
C031927hydroquinoneWRN protein inhibits the reaction [hydroquinone results in increased cleavage of CASP7 protein]19064679
D006918HydroxyureaHydroxyurea results in increased expression of CASP7 mRNA27208086
D000068877Imatinib MesylateImatinib Mesylate results in increased cleavage of CASP7 protein28315715
D000068877Imatinib MesylateSH3BP5 protein affects the reaction [Imatinib Mesylate results in increased cleavage of CASP7 protein]28315715
D007099ImipramineImipramine results in increased activity of CASP7 protein22700542
D007099ImipraminePalmitic Acid promotes the reaction [Imipramine results in increased activity of CASP7 protein]22700542
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CASP7 mRNA28628672
C572449INK128INK128 results in increased cleavage of CASP7 protein26536665
C030956insecticidal crystal protein, Bacillus Thuringiensis"insecticidal crystal protein, Bacillus Thuringiensis inhibits the reaction [Herbicides results in increased activity of CASP7 protein]"22337346
C551631isoangustone Aisoangustone A results in increased cleavage of CASP7 protein20229524
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CASP7 mRNA28628672
D007530IsofluraneIsoflurane inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP7 protein]16249675
D007530IsofluraneIsoflurane results in increased expression of CASP7 mRNA16978161
D007545IsoproterenolAcetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein]17136323
D007545IsoproterenolIsoproterenol results in increased activity of and results in increased cleavage of CASP7 protein17136323
D007545IsoproterenolIsoproterenol results in decreased expression of CASP7 mRNA24286936
C561695(+)-JQ1 compound[EGFR gene mutant form results in increased susceptibility to (+)-JQ1 compound] which results in increased activity of CASP7 protein26455392
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased activity of CASP7 protein22904298|2340363
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased cleavage of CASP7 protein23872705
C510621KCC 009KCC 009 results in increased cleavage of CASP7 protein16170020
D007654KetoconazoleKetoconazole results in increased expression of CASP7 mRNA25808816
C477361LAQ824[LAQ824 co-treated with fludarabine] results in increased activity of CASP7 protein18852132
C017461lead nitratelead nitrate affects the reaction [CASP7 affects the expression of MT1 mRNA]11891201
C017461lead nitratelead nitrate affects the reaction [CASP7 affects the expression of MT2 mRNA]11891201
C017461lead nitratelead nitrate results in decreased expression of CASP7 mRNA11891201
D001556Lindane[Lindane co-treated with Dieldrin] results in increased activity of CASP7 protein20036686
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of CASP7 protein"21239534
C440499lipopolysaccharide, Escherichia coli O111 B4"[zinc chloride co-treated with pyrithione] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of CASP7 protein]"21239534
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CASP7 protein21844306
D008070Lipopolysaccharides[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP7 protein21146893
D008070LipopolysaccharidesUrsodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP7 protein]21146893
D008094LithiumLithium inhibits the reaction [Monensin results in increased activity of CASP7 protein]20799912
D017336LoratadineLoratadine results in increased activity of CASP7 protein22700542
D017336LoratadinePalmitic Acid promotes the reaction [Loratadine results in increased activity of CASP7 protein]22700542
D047311LuteolinLuteolin results in increased activity of CASP7 protein21074525
C013099mancozebmancozeb results in increased activity of CASP7 protein22824503
D008344ManebManeb results in increased activity of CASP7 protein22824503
D008345ManganeseManganese results in increased activity of CASP7 protein22427945
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[XCT790 results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP7 protein]19464277
C021053mangostinESR1 protein affects the reaction [mangostin results in increased activity of CASP7 protein]24480042
C021053mangostinmangostin results in increased activity of CASP7 protein24480042
D009637MasoprocolMasoprocol inhibits the reaction [[TNF protein co-treated with Cycloheximide] results in increased activity of CASP7 protein]15950244
C019476mecobalaminmecobalamin inhibits the reaction [Homocysteine results in increased activity of CASP7 protein]21237187
D008627Mercuric ChlorideAcetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP7 protein]22909951
D008627Mercuric Chloride[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP7 protein22909951
D008627Mercuric ChlorideMercuric Chloride results in increased expression of CASP7 mRNA23202902
D008687MetforminCisplatin promotes the reaction [Metformin results in increased activity of CASP7 protein]21388661
D008687MetforminMetformin inhibits the reaction [sunitinib results in increased cleavage of CASP7 protein]21906609
D008687MetforminMetformin results in increased activity of CASP7 protein21388661
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CASP7 mRNA20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CASP7 gene20938992
D008727MethotrexateESRRA protein inhibits the reaction [Methotrexate results in increased cleavage of CASP7 protein]24967384
D008727Methotrexate[Methotrexate co-treated with CDKN1A protein] results in increased cleavage of CASP7 protein18483502
D008727Methotrexate[Methotrexate co-treated with CDKN1A protein] results in increased expression of CASP7 mRNA18483502
D008727MethotrexateMethotrexate results in increased cleavage of CASP7 protein18483502|2496738
D008727MethotrexateMethotrexate results in increased expression of CASP7 mRNA21678067
C013598methoxyacetic acid[1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased cleavage of and results in increased activity of CASP7 protein26006246
D008731MethoxychlorESR1 gene mutant form promotes the reaction [Methoxychlor results in increased activity of CASP7 protein]22306526
D008731MethoxychlorMethoxychlor results in increased activity of CASP7 protein20568958|2230652
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of CASP7 mRNA23202902
D008767Methylmercury CompoundsAcetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP7 mRNA]21549813
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased expression of CASP7 mRNA26558463
D008767Methylmercury CompoundsMethylmercury Compounds results in increased cleavage of CASP7 protein21549813
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of CASP7 mRNA21549813
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased activity of CASP7 protein24989254
C008493methylselenic acidAcetylcysteine inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]28161410
C008493methylselenic acidHSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]16204082
C008493methylselenic acidmethylselenic acid inhibits the reaction [CASP7 protein binds to HSPA5 protein]16204082
C008493methylselenic acidmethylselenic acid results in increased cleavage of CASP7 protein16204082|1879078
C008493methylselenic acidSodium Selenite inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]28161410
C008493methylselenic acidTamoxifen promotes the reaction [methylselenic acid results in increased cleavage of CASP7 protein]18790785
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in increased activity of CASP7 protein]20427495
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in increased cleavage of CASP7 protein]20045437
D008911MinocyclineMinocycline results in decreased expression of and results in decreased activity of CASP7 protein14998631
D008911MinocyclineMinocycline results in decreased expression of CASP7 mRNA14998631
D016685MitomycinMitomycin results in increased cleavage of and results in increased activity of CASP7 protein12181741
D008942MitoxantroneMitoxantrone results in increased activity of CASP7 protein12948851|2270054
D008942MitoxantronePalmitic Acid promotes the reaction [Mitoxantrone results in increased activity of CASP7 protein]22700542
D008982MolybdenumMolybdenum analog results in increased activity of CASP7 protein26391003
D008985MonensinLithium inhibits the reaction [Monensin results in increased activity of CASP7 protein]20799912
D008985MonensinMonensin results in increased activity of CASP7 protein20799912
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased activity of CASP7 protein23360888
C517284monomethyl phthalatemonomethyl phthalate affects the expression of CASP7 mRNA26924002
C047806monomethylpropionmonomethylpropion results in increased expression of CASP7 mRNA22303338
C008548morinmorin results in increased activity of CASP7 protein24726691
D009151Mustard Gasacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Mustard Gas results in increased cleavage of CASP7 protein]12482751
D009151Mustard GasBRCA2 protein inhibits the reaction [Mustard Gas results in increased cleavage of CASP7 protein]20435105
D009151Mustard GasCALM1 protein promotes the reaction [Mustard Gas results in increased cleavage of and results in increased activity of CASP7 protein]16935404
D009151Mustard GasFADD protein affects the reaction [Mustard Gas results in increased cleavage of CASP7 protein]12482751
D009151Mustard GasMustard Gas promotes the reaction [CASP3 protein results in increased cleavage of CASP7 protein]12482751
D009151Mustard GasMustard Gas results in increased activity of CASP7 protein12482751
D009151Mustard GasMustard Gas results in increased cleavage of and results in increased activity of CASP7 protein16935404
D009151Mustard GasMustard Gas results in increased cleavage of CASP7 protein20435105
D009151Mustard GasMustard Gas results in increased expression of CASP7 mRNA15674843
C455139myrtucommulone Amyrtucommulone A results in decreased expression of CASP7 mRNA26032814
C562237N-(2-(2-(4-(4-(2-hydroxypropyl)piperazin-1-yl)-2-methoxyphenylamino)pyrrolo(2,1-f)(1,2,4)triazin-7-yl)phenyl)-N-methylmethanesulfonamide"[ALK protein modified form results in increased susceptibility to N-(2-(2-(4-(4-(2-hydroxypropyl)piperazin-1-yl)-2-methoxyphenylamino)pyrrolo(2,1-f)(1,2,4)triazin-7-yl)phenyl)-N-methylmethanesulfonamide] which results in increased activity of CASP7 protein"21859094
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [cadmium sulfate results in increased activity of CASP7 protein]14687664
C109860N-(3-oxododecanoyl)homoserine lactoneN-(3-oxododecanoyl)homoserine lactone results in increased activity of CASP7 protein25627690
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CASP7 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of CASP7 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CASP7 mRNA"25554681
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of CASP7 mRNA25380136
C005273naringeninnaringenin results in increased expression of CASP7 protein modified form27838343
C101954N-caproylsphingosineN-caproylsphingosine results in increased expression of CASP7 protein modified form25195822
C112341NCQ 344benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [NCQ 344 results in increased activity of CASP7 protein]10996300
C112341NCQ 344NCQ 344 results in increased activity of CASP7 protein10996300
C084325NCQ 436benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [NCQ 436 results in increased activity of CASP7 protein]10996300
C084325NCQ 436NCQ 436 results in increased activity of CASP7 protein10996300
C051752nefazodonenefazodone results in increased activity of CASP7 protein22700542
C051752nefazodonePalmitic Acid promotes the reaction [nefazodone results in increased activity of CASP7 protein]22700542
D019888NelfinavirNelfinavir results in increased activity of CASP7 protein20105315
D009532NickelBECN1 protein promotes the reaction [Nickel results in increased expression of CASP7 protein modified form]28330870
D009532Nickelbenzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Nickel results in increased expression of CASP7 protein modified form]28330870
D009532NickelNickel results in increased cleavage of and results in increased activity of CASP7 protein24068677
D009532NickelNickel results in increased expression of CASP7 protein modified form28330870
C022838nickel chloridecobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of CASP7 protein]22172632
C022838nickel chloridenickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of CASP7 protein]22172632
C022838nickel chloridenickel chloride results in increased cleavage of CASP7 protein21828359|2217263
C022838nickel chloride[nickel chloride co-treated with Chlorpyrifos] affects the expression of CASP7 mRNA21496282
C022838nickel chloridenickel chloride affects the expression of CASP7 mRNA22546817
C022838nickel chloridenickel chloride results in increased activity of CASP7 protein21843586
C022838nickel chloridepyrazolanthrone inhibits the reaction [nickel chloride results in increased activity of CASP7 protein]21843586
C028007nickel monoxidenickel monoxide results in increased cleavage of CASP7 protein21828359
D009534NiclosamideNiclosamide results in increased expression of CASP7 protein modified form26116531
C002714nimetazepamCYP3A4 protein affects the reaction [nimetazepam results in increased activity of CASP7 protein]19005028
D009553NimodipineNimodipine results in increased activity of CASP7 protein22700542
D009553NimodipinePalmitic Acid promotes the reaction [Nimodipine results in increased activity of CASP7 protein]22700542
D009567NitrazepamCYP3A4 protein affects the reaction [Nitrazepam results in increased activity of CASP7 protein]19005028
D009569Nitric OxideNitric Oxide results in decreased cleavage of CASP7 protein10222263
D009599NitroprussideNitroprusside results in increased activity of CASP7 protein22178905
D009599NitroprussideNitroprusside results in increased expression of CASP7 mRNA15708893
D009599NitroprussideUrsodeoxycholic Acid inhibits the reaction [Nitroprusside results in increased activity of CASP7 protein]22178905
D009599Nitroprussidecilostazol inhibits the reaction [Nitroprusside results in increased activity of CASP7 protein]18311796
D009599NitroprussideNitroprusside results in increased activity of CASP7 protein18311796
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of CASP7 protein"21239534
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of CASP7 protein]"21239534
D009638NorepinephrineAcetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP7 protein]17136323
D009638NorepinephrineNorepinephrine results in increased activity of and results in increased cleavage of CASP7 protein17136323
D009661NortriptylineNortriptyline results in increased activity of CASP7 protein22700542
D009661NortriptylinePalmitic Acid promotes the reaction [Nortriptyline results in increased activity of CASP7 protein]22700542
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased activity of CASP7 protein20971185
C558013NSC 689534NSC 689534 results in increased activity of CASP7 protein20971185
C482205nutlin 3nutlin 3 results in increased activity of CASP7 protein22260869
C482205nutlin 3TP53 mutant form inhibits the reaction [nutlin 3 results in increased activity of CASP7 protein]22260869
C474958O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"Buthionine Sulfoximine promotes the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate affects the cleavage of CASP7 protein]"20962031
C474958O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate affects the cleavage of CASP7 protein"20962031
C474958O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate analog results in increased cleavage of CASP7 protein"22003962
C474958O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in increased cleavage of CASP7 protein"20962031
C025589ochratoxin Aochratoxin A results in decreased expression of CASP7 mRNA17316727
C025589ochratoxin Aochratoxin A results in increased activity of CASP7 protein25002221
C025589ochratoxin AU 0126 inhibits the reaction [ochratoxin A results in increased activity of CASP7 protein]25002221
C025589ochratoxin Awortmannin promotes the reaction [ochratoxin A results in increased activity of CASP7 protein]25002221
C025589ochratoxin Aochratoxin A results in increased expression of CASP7 mRNA19562491
D016627OxidopamineLevodopa inhibits the reaction [Oxidopamine results in increased expression of CASP7 mRNA]25129099
D016627OxidopamineOxidopamine results in increased expression of CASP7 mRNA25129099
D016627OxidopamineRutin inhibits the reaction [Oxidopamine results in increased expression of CASP7 mRNA]25129099
D019319Okadaic AcidOkadaic Acid results in increased cleavage of and results in increased activity of CASP7 protein19084044
C507134ON 01910ON 01910 results in increased activity of CASP7 protein21812421|2447187
C507134ON 01910ON 01910 results in increased cleavage of CASP7 protein19198627|2531676
C016340o,p'-DDT"o,p'-DDT analog results in decreased expression of CASP7 mRNA"22937105
C016340o,p'-DDT"o,p'-DDT results in increased expression of CASP7 mRNA"22937105
D009942Organometallic CompoundsOrganometallic Compounds results in increased activity of CASP7 protein24781711|2639100
D008939MitotaneMitotane results in increased activity of CASP7 protein23254310
D008939MitotaneMitotane results in increased expression of CASP7 mRNA23485034
C106408OSW 1OSW 1 analog results in increased activity of CASP7 protein21438635
D017239Paclitaxel[Doxorubicin co-treated with Paclitaxel co-treated with Fluorouracil] results in increased activity of CASP7 protein16168113
D017239PaclitaxelPaclitaxel results in increased activity of CASP7 protein22302033
D017239PaclitaxelPaclitaxel results in increased cleavage of CASP7 protein27664577
D017239PaclitaxelPaclitaxel results in increased expression of CASP7 mRNA18058816
D017239Paclitaxelpalbociclib inhibits the reaction [Paclitaxel results in increased activity of CASP7 protein]22302033
D017239Paclitaxel[resveratrol co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of CASP7 protein14749477
D017239Paclitaxel[Sirolimus co-treated with Paclitaxel] results in increased cleavage of CASP7 protein15753396
C500026palbociclibpalbociclib inhibits the reaction [Camptothecin results in increased activity of CASP7 protein]22302033
C500026palbociclibpalbociclib inhibits the reaction [Carboplatin results in increased activity of CASP7 protein]22302033
C500026palbociclibpalbociclib inhibits the reaction [Doxorubicin results in increased activity of CASP7 protein]22302033
C500026palbociclibpalbociclib inhibits the reaction [Etoposide results in increased activity of CASP7 protein]22302033
C500026palbociclibpalbociclib inhibits the reaction [Paclitaxel results in increased activity of CASP7 protein]22302033
C500026palbociclib[CDKN2A gene mutant form results in increased susceptibility to palbociclib] which affects the activity of CASP7 protein24098593
D019308Palmitic AcidPalmitic Acid promotes the reaction [alpidem results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Clomipramine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Clozapine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Cyclosporine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Dipyridamole results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Estrone results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [fipexide results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Flecainide results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Fluoxetine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Fluvoxamine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Imipramine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Loratadine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Mitoxantrone results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [nefazodone results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Nimodipine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Nortriptyline results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Phentolamine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Pyrimethamine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Riluzole results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Risperidone results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Spironolactone results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [Ticlopidine results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [troglitazone results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid promotes the reaction [zileuton results in increased activity of CASP7 protein]22700542
D019308Palmitic AcidPalmitic Acid results in increased activity of CASP7 protein17194744|2241301
D019308Palmitic Acid[TO-901317 co-treated with alitretinoin] promotes the reaction [Palmitic Acid results in increased activity of CASP7 protein]17194744
D019308Palmitic AcidTO-901317 promotes the reaction [Palmitic Acid results in increased activity of CASP7 protein]17194744
D010269ParaquatCAT protein inhibits the reaction [Paraquat results in increased activity of CASP7 protein]24866057
D010269ParaquatParaquat results in increased activity of CASP7 protein24866057
D010269ParaquatParaquat results in increased expression of CASP7 mRNA18836921
D010269ParaquatNFE2L2 mutant form inhibits the reaction [Paraquat results in increased activity of CASP7 protein]22678742
D010269ParaquatParaquat results in increased activity of CASP7 protein17324951|2267874
C000610380p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane"p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane results in increased cleavage of CASP7 protein"26035713
D010424PentobarbitalPentobarbital results in increased expression of CASP7 mRNA16978161
D010646PhentolaminePalmitic Acid promotes the reaction [Phentolamine results in increased activity of CASP7 protein]22700542
D010646PhentolaminePhentolamine results in increased activity of CASP7 protein22700542
C005435phenylmethylpyrazolonephenylmethylpyrazolone analog results in increased activity of CASP7 protein25684395
C522973PI103PI103 promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]23300809
C522973PI103PI103 promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]21616090
C121565pifithrinpifithrin promotes the reaction [Etoposide results in increased activity of CASP7 protein]26259609
C121565pifithrinpifithrin inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]24704558
C006253pirinixic acidpirinixic acid results in increased expression of CASP7 mRNA19162173
D010936Plant ExtractsPlant Extracts inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP7 protein]27050144
D010936Plant ExtractsPlant Extracts results in increased activity of CASP7 protein22705325
D010936Plant ExtractsPlant Extracts results in increased cleavage of CASP7 protein20229524
D010936Plant ExtractsPlant Extracts results in increased activity of CASP7 protein19329757
D028321Plant PreparationsPlant Preparations affects the expression of CASP7 mRNA16046712
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of CASP7 protein modified form25977998
D011192Potassium DichromatePotassium Dichromate results in decreased expression of CASP7 protein23718831
D011192Potassium Dichromate[Cadmium Chloride co-treated with Potassium Dichromate] results in increased expression of CASP7 mRNA25409916
D011192Potassium DichromatePotassium Dichromate results in increased expression of CASP7 mRNA25409916
C066229prolinedithiocarbamatebenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein]21035945
C066229prolinedithiocarbamate[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased activity of CASP7 protein21035945
C066229prolinedithiocarbamateAcetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP7 protein]22909951
C066229prolinedithiocarbamate[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP7 protein22909951
D011405PropafenonePropafenone results in increased activity of CASP7 protein22700542
D011433PropranololPropranolol results in increased activity of CASP7 protein22700542
C527556Pt(O,O'-acac)(gamma-acac)(DMS)"Pt(O,O'-acac)(gamma-acac)(DMS) results in increased activity of CASP7 protein"21420390
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]21843585
C432165pyrazolanthronepyrazolanthrone promotes the reaction [dihydromyricetin results in increased cleavage of CASP7 protein]27539140
C432165pyrazolanthronepyrazolanthrone promotes the reaction [usnic acid results in increased activity of CASP7 protein]25078063
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]24157283
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [TEMPO results in increased activity of CASP7 protein]25882087
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Copper results in increased activity of CASP7 protein]16672322
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP7 protein]23405080
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein]20920558
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [nickel chloride results in increased activity of CASP7 protein]21843586
C031280pyrazolepyrazole results in decreased expression of CASP7 mRNA17945193
D011739PyrimethaminePalmitic Acid promotes the reaction [Pyrimethamine results in increased activity of CASP7 protein]22700542
D011739PyrimethaminePyrimethamine results in increased activity of CASP7 protein22700542
C008704pyrithione"[zinc chloride co-treated with pyrithione] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of CASP7 protein]"21239534
C010423pyrithione zincpyrithione zinc results in increased activity of CASP7 protein20151177
C020972pyrrolidine dithiocarbamic acidAcetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]22085843
C020972pyrrolidine dithiocarbamic acid[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein22085843
C020972pyrrolidine dithiocarbamic acid[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein20920558
C020972pyrrolidine dithiocarbamic acidMAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]20920558
C020972pyrrolidine dithiocarbamic acidpyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein]20920558
D011794Quercetin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased cleavage of CASP7 protein]14688022
D011794QuercetinHSPA5 protein inhibits the reaction [Quercetin results in increased expression of CASP7 protein modified form]19017364
D011794QuercetinMCL1 protein inhibits the reaction [Quercetin results in increased activity of CASP7 protein]21138867
D011794QuercetinQuercetin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP7 protein]27050144
D011794QuercetinQuercetin results in increased activity of CASP7 protein21138867|2472669
D011794QuercetinQuercetin results in increased cleavage of CASP7 protein14688022|1878722
D011794QuercetinQuercetin results in increased expression of CASP7 protein14767529
D011794QuercetinQuercetin results in increased expression of CASP7 protein modified form19017364
D011794QuercetinU 0126 inhibits the reaction [Quercetin results in increased cleavage of CASP7 protein]14688022
C468548quinoline-val-asp(OMe)-CH2-OPHquinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [Copper results in increased activity of CASP7 protein]16672322
C004532quinonequinone results in decreased activity of CASP7 protein22960397
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride affects the expression of CASP7 mRNA14699072
D020849Raloxifene Hydrochloride[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA19059307
D011929RazoxaneRazoxane results in increased activity of CASP7 protein10487526
D017382Reactive Oxygen Speciesmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[XCT790 results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP7 protein]19464277
D017382Reactive Oxygen Species[XCT790 results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP7 protein19464277
C059514resveratrolATF3 protein promotes the reaction [resveratrol results in increased activity of CASP7 protein]21205742
C059514resveratrolBCL2L1 protein affects the reaction [[clofarabine co-treated with resveratrol] results in increased activity of CASP7 protein]25408576
C059514resveratrolbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[resveratrol co-treated with clofarabine] promotes the reaction [MCL1 mutant form results in increased activity of CASP7 protein]]24924397
C059514resveratrolbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[resveratrol co-treated with clofarabine] results in increased activity of CASP7 protein]24924397
C059514resveratrol[clofarabine co-treated with resveratrol] promotes the reaction [BCL2L1 mutant form results in increased activity of CASP7 protein]25408576
C059514resveratrol[clofarabine co-treated with resveratrol] results in increased activity of CASP7 protein25408576
C059514resveratrol[resveratrol co-treated with clofarabine] promotes the reaction [MCL1 mutant form results in increased activity of CASP7 protein]24924397
C059514resveratrol[resveratrol co-treated with clofarabine] results in increased activity of CASP7 protein24924397
C059514resveratrol[resveratrol co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of CASP7 protein14749477
C059514resveratrolresveratrol inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein]19959636
C059514resveratrolresveratrol promotes the reaction [TNFSF10 protein results in increased cleavage of CASP7 protein]17823925
C059514resveratrolresveratrol results in increased activity of CASP7 protein19738051|2120574
C059514resveratrolresveratrol results in increased cleavage of CASP7 protein23152798
C059514resveratrolresveratrol results in increased expression of CASP723495037
C059514resveratrolresveratrol results in decreased activity of CASP7 protein23227865
C059514resveratrol[resveratrol co-treated with Estradiol] results in increased activity of CASP7 protein24894866
C059514resveratrolresveratrol inhibits the reaction [Tobacco Smoke Pollution results in increased activity of CASP7 protein]18424637
C059514resveratrolresveratrol results in increased activity of CASP7 protein24894866
C059514resveratrolSIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Tobacco Smoke Pollution results in increased activity of CASP7 protein]]18424637
D012254RibavirinRibavirin promotes the reaction [FAS protein results in increased activity of CASP7 protein]12760867
D019782RiluzolePalmitic Acid promotes the reaction [Riluzole results in increased activity of CASP7 protein]22700542
D019782RiluzoleRiluzole results in increased activity of CASP7 protein22700542
D018967RisperidonePalmitic Acid promotes the reaction [Risperidone results in increased activity of CASP7 protein]22700542
D018967RisperidoneRisperidone results in increased activity of CASP7 protein22700542
D012402RotenoneMT1B protein inhibits the reaction [Rotenone results in increased activity of CASP7 protein]16402917
D012402RotenoneMT2A protein inhibits the reaction [Rotenone results in increased activity of CASP7 protein]16402917
D012402RotenoneRotenone results in increased activity of CASP7 protein16402917
C046245rubimaillinBCL2L1 protein inhibits the reaction [rubimaillin results in increased activity of CASP7 protein]19716835
C046245rubimaillinbenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [rubimaillin results in increased activity of CASP7 protein]19716835
C046245rubimaillinrubimaillin results in increased activity of CASP7 protein19716835
D012431RutinRutin results in increased activity of CASP7 protein24726691
D012431RutinRutin inhibits the reaction [Oxidopamine results in increased expression of CASP7 mRNA]25129099
C033110RV 538RV 538 results in increased expression of CASP7 protein modified form25195822
C039961S-(1,2-dichlorovinyl)cysteine"alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP7 protein]"29129777
C039961S-(1,2-dichlorovinyl)cysteine"S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP7 protein"29129777
C413684salicylaldehyde isonicotinoyl hydrazonesalicylaldehyde isonicotinoyl hydrazone analog results in increased activity of CASP7 protein22521999
C000687salicyl hydrazidesalicyl hydrazide analog results in increased activity of CASP7 protein25684395
C093642SB 203580SB 203580 inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
C093642SB 203580SB 203580 inhibits the reaction [DDT results in increased activity of CASP7 protein]15603917
C093642SB 203580SB 203580 inhibits the reaction [chloroacetic acid results in increased activity of CASP7 protein]23103613
C093642SB 203580SB 203580 inhibits the reaction [Copper results in increased activity of CASP7 protein]16672322
C115461SC 560SC 560 results in increased activity of CASP7 protein16391822
C499748SCIO-469SCIO-469 promotes the reaction [Bortezomib results in increased cleavage of CASP7 protein]16617327
D020280Sertraline4-phenylbutyric acid inhibits the reaction [Sertraline results in increased activity of CASP7 protein]24865413
D020280SertralineSertraline results in increased activity of CASP7 protein24865413
C025583sesamolsesamol results in increased activity of CASP7 protein27270451
C009250sevofluranesevoflurane results in increased activity of CASP7 protein16678324
D022641Shiga Toxin 2Shiga Toxin 2 results in increased activity of CASP7 protein12826277
D022641Shiga Toxin 2Terbutaline inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP7 protein]12826277
D022641Shiga Toxin 2[Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP7 protein]12826277
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in increased activity of CASP7 protein]20427495
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in increased cleavage of CASP7 protein]20045437
D019821SimvastatinSimvastatin results in increased activity of CASP7 protein20427495
D019821SimvastatinSimvastatin results in increased cleavage of and results in increased activity of CASP7 protein19253821|2004543
D020123Sirolimus[Curcumin co-treated with Sirolimus] results in increased activity of CASP7 protein19373661
D020123Sirolimus[Sirolimus co-treated with Paclitaxel] results in increased cleavage of CASP7 protein15753396
D020123SirolimusSirolimus results in decreased activity of CASP7 protein20031680
C017947sodium arseniteEIF4E protein modified form inhibits the reaction [sodium arsenite results in increased activity of CASP7 protein]25923732
C017947sodium arsenitesodium arsenite results in decreased expression of CASP7 mRNA12760830
C017947sodium arsenitesodium arsenite results in increased activity of CASP7 protein17202112|2592373
C017947sodium arsenitesodium arsenite results in increased cleavage of CASP7 protein21642427
C017947sodium arsenitesodium arsenite results in increased activity of CASP7 protein16447264
C016104sodium bichromateCAT protein inhibits the reaction [sodium bichromate results in increased activity of CASP7 protein]20298709
C016104sodium bichromatesodium bichromate results in increased activity of CASP7 protein20298709
C016104sodium bichromateTRP53 mutant form inhibits the reaction [sodium bichromate results in increased activity of CASP7 protein]20298709
D018038Sodium SeleniteSodium Selenite affects the expression of CASP7 mRNA16705456
D018038Sodium SeleniteSodium Selenite inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]28161410
D018038Sodium SeleniteSodium Selenite results in increased cleavage of CASP7 protein28161410
D012999SomanSoman results in increased expression of CASP7 mRNA19281266
D053260SootSoot results in increased expression of CASP7 protein modified form24464499
C471405sorafenib[sorafenib co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP7 protein17909059
C471405sorafenibsorafenib results in increased activity of CASP7 protein19770576|2005464
C471405sorafenibsorafenib results in increased cleavage of and results in increased activity of CASP7 protein16109713
D013096SpermineSpermine results in decreased activity of CASP7 protein11281655
D013148SpironolactonePalmitic Acid promotes the reaction [Spironolactone results in increased activity of CASP7 protein]22700542
D013148SpironolactoneSpironolactone results in increased activity of CASP7 protein22700542
C525422SRT1720SRT1720 results in increased activity of CASP7 protein26055805
D019311StaurosporineDOCK1 protein inhibits the reaction [Staurosporine results in increased activity of CASP7 protein]25586182
D019311StaurosporineELMO1 protein inhibits the reaction [Staurosporine results in increased activity of CASP7 protein]25586182
D019311StaurosporineEOMES protein inhibits the reaction [Staurosporine results in increased expression of CASP7 protein modified form]27539959
D019311StaurosporineStaurosporine results in increased activity of CASP7 protein16402917|1883209
D019311StaurosporineStaurosporine results in increased cleavage of CASP7 protein26124276
D019311StaurosporineStaurosporine results in increased expression of CASP7 protein modified form27539959
D019311StaurosporineEGF protein inhibits the reaction [Staurosporine results in increased activity of CASP7 protein]19406941
D019311StaurosporineIGF1 protein inhibits the reaction [Staurosporine results in increased activity of CASP7 protein]19406941
D019311StaurosporineStaurosporine results in increased activity of CASP7 protein19406941
C031183stearic acidstearic acid results in increased activity of CASP7 protein22413010
D013311StreptozocinStreptozocin results in increased expression of CASP7 protein15976052
C016766sulforafansulforafan results in increased activity of CASP7 protein17942926
C025462sulindac sulfide[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein20371263
C025462sulindac sulfidetempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein]20371263
C473478sunitinibAICA ribonucleotide inhibits the reaction [sunitinib results in increased cleavage of CASP7 protein]21906609
C473478sunitinibMetformin inhibits the reaction [sunitinib results in increased cleavage of CASP7 protein]21906609
C473478sunitinibsunitinib results in increased cleavage of CASP7 protein21906609
D013501Surface-Active Agents[Surface-Active Agents co-treated with glyphosate] results in increased activity of CASP7 protein23099315
D013605T-2 ToxinBentonite inhibits the reaction [[HT-2 toxin co-treated with T-2 Toxin] results in increased expression of CASP7 mRNA]25296281
D013605T-2 Toxin[HT-2 toxin co-treated with T-2 Toxin] results in increased expression of CASP7 mRNA25296281
D013605T-2 ToxinT-2 Toxin results in increased activity of CASP7 protein19524637
D013629TamoxifenTamoxifen affects the expression of CASP7 mRNA14699072
D013629Tamoxifen[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA19059307
D013629TamoxifenTamoxifen promotes the reaction [methylselenic acid results in increased cleavage of CASP7 protein]18790785
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid inhibits the reaction [SERPINA1 protein mutant form results in increased activity of CASP7 protein]17559149
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid inhibits the reaction [Thapsigargin results in increased activity of CASP7 protein]12198651
C508490TDP 521252TDP 521252 results in increased activity of CASP7 protein16432175
C047246temozolomidetemozolomide results in increased activity of CASP7 protein26911376
C003959TEMPOpyrazolanthrone inhibits the reaction [TEMPO results in increased activity of CASP7 protein]25882087
C003959TEMPOTEMPO results in increased activity of CASP7 protein25882087
C001803tempoltempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein]20371263
D013726TerbutalineTerbutaline inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP7 protein]12826277
D013726Terbutaline[Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP7 protein]12826277
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased activity of CASP7 protein22485137
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP7 protein]20299546
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CASP7 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CASP7 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CASP7 mRNA12167310
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CASP7 mRNA19520675
D0156472,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine"2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of and results in increased cleavage of CASP7 protein"17136323
D0156472,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine"Acetylcysteine inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of and results in increased cleavage of CASP7 protein]"17136323
D019284ThapsigarginDoxorubicin inhibits the reaction [Thapsigargin results in increased activity of and results in increased cleavage of CASP7 protein]16298333
D019284Thapsigargintauroursodeoxycholic acid inhibits the reaction [Thapsigargin results in increased activity of CASP7 protein]12198651
D019284ThapsigarginThapsigargin results in increased activity of and results in increased cleavage of CASP7 protein16298333
D019284ThapsigarginThapsigargin results in increased activity of CASP7 protein12198651|1755914
D013988TiclopidinePalmitic Acid promotes the reaction [Ticlopidine results in increased activity of CASP7 protein]22700542
D013988TiclopidineTiclopidine results in increased activity of CASP7 protein22700542
C009495titanium dioxidetitanium dioxide results in increased activity of CASP7 protein19783790
C423915TO-901317[TO-901317 co-treated with alitretinoin] promotes the reaction [Palmitic Acid results in increased activity of CASP7 protein]17194744
C423915TO-901317TO-901317 promotes the reaction [Palmitic Acid results in increased activity of CASP7 protein]17194744
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of CASP7 mRNA15289447
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CASP7 mRNA16137721
D014028Tobacco Smoke Pollutionresveratrol inhibits the reaction [Tobacco Smoke Pollution results in increased activity of CASP7 protein]18424637
D014028Tobacco Smoke PollutionSIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Tobacco Smoke Pollution results in increased activity of CASP7 protein]]18424637
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased activity of CASP7 protein18424637
D019772Topotecan[Amlodipine co-treated with Topotecan] results in increased activity of CASP7 protein16516327
D014108Tosylphenylalanyl Chloromethyl KetoneTosylphenylalanyl Chloromethyl Ketone results in increased cleavage of and results in increased activity of CASP7 protein12821135
D014108Tosylphenylalanyl Chloromethyl KetoneTP53 protein promotes the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased activity of CASP7 protein]12821135
D014118Toxins, Biological"Toxins, Biological affects the expression of CASP7 mRNA"19682533
C560077trametinib"[GNAQ gene mutant form results in increased susceptibility to [trametinib co-treated with 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide]] which results in increased cleavage of CASP7 protein"22733540
D014212TretinoinCRABP2 protein promotes the reaction [Tretinoin results in increased cleavage of and results in increased activity of CASP7 protein]16166294
D014212TretinoinCycloheximide inhibits the reaction [Tretinoin results in increased expression of CASP7 mRNA]16166294
D014212Tretinoin[Tretinoin co-treated with zoledronic acid] results in increased activity of CASP7 protein20349282
D014212TretinoinTretinoin results in increased cleavage of and results in increased activity of CASP7 protein16166294
D014212TretinoinTretinoin results in increased expression of CASP7 mRNA15894607|1616629
D014212TretinoinTretinoin promotes the reaction [arsenic trioxide results in increased cleavage of CASP7 protein]15688020
C011559tributyltintributyltin results in decreased expression of CASP7 mRNA27614199
C011559tributyltintributyltin results in increased activity of CASP7 protein21683754
C012589trichostatin A[Bortezomib co-treated with trichostatin A] results in increased cleavage of and results in increased activity of CASP7 protein16904634
C012589trichostatin Atrichostatin A results in increased expression of CASP7 mRNA24935251
C012589trichostatin Atrichostatin A results in decreased expression of CASP7 mRNA23558232
C001899triptolidetriptolide results in increased activity of CASP7 protein21640813
C057693troglitazonePalmitic Acid promotes the reaction [troglitazone results in increased activity of CASP7 protein]22700542
C057693troglitazonetroglitazone results in increased activity of CASP7 protein22700542
C080163trovafloxacintrovafloxacin results in decreased expression of CASP7 mRNA24136188
D014415TunicamycinTunicamycin results in increased activity of CASP7 protein19139269
C113580U 0126U 0126 inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
C113580U 0126U 0126 inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]21843585
C113580U 0126U 0126 inhibits the reaction [ochratoxin A results in increased activity of CASP7 protein]25002221
C113580U 0126U 0126 inhibits the reaction [Quercetin results in increased cleavage of CASP7 protein]14688022
C113580U 0126U 0126 promotes the reaction [dihydromyricetin results in increased cleavage of CASP7 protein]27539140
C113580U 0126U 0126 promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]21616090
C113580U 0126U 0126 inhibits the reaction [Copper results in increased activity of CASP7 protein]16672322
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid analog inhibits the reaction [TNF protein results in increased activity of CASP7 protein]21146893
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [Nitroprusside results in increased activity of CASP7 protein]22178905
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP7 protein]21146893
C005466ursolic acidursolic acid results in increased activity of CASP7 protein19329757
C073339usnic acid3-methyladenine promotes the reaction [usnic acid results in increased activity of CASP7 protein]25078063
C073339usnic acid4-phenylbutyric acid inhibits the reaction [usnic acid results in increased activity of CASP7 protein]25870318
C073339usnic acidChloroquine promotes the reaction [usnic acid results in increased activity of CASP7 protein]25078063
C073339usnic acidpyrazolanthrone promotes the reaction [usnic acid results in increased activity of CASP7 protein]25078063
C073339usnic acidusnic acid results in increased activity of CASP7 protein25078063|2587031
D014635Valproic AcidValproic Acid affects the expression of CASP7 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of CASP7 mRNA23179753|2493525
D017968Vanadium CompoundsVanadium Compounds results in increased activity of CASP7 protein26391003
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of CASP7 gene25487561
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of CASP7 gene25560391
D014700Verapamil[Verapamil results in decreased expression of ABCB1] promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]15861398
C025643vinclozolinvinclozolin results in decreased expression of CASP7 mRNA23034163
C030852vinorelbine[Cisplatin co-treated with vinorelbine] results in decreased expression of CASP7 mRNA21544650
D014757Viper VenomsViper Venoms results in increased expression of CASP7 mRNA27613483
D014757Viper VenomsViper Venoms results in increased expression of CASP7 protein27613483
D014801Vitamin A"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased activity of CASP7 protein]"17942326
D014801Vitamin AVitamin A results in increased activity of CASP7 protein17942326
C111237vorinostat[decitabine co-treated with vorinostat] affects the expression of CASP7 mRNA17330099
C111237vorinostatvorinostat results in increased cleavage of CASP7 protein15897598
C009687wortmanninwortmannin inhibits the reaction [Acrolein results in increased activity of CASP7 protein]17196791
C009687wortmanninwortmannin promotes the reaction [ochratoxin A results in increased activity of CASP7 protein]25002221
C104536xanthohumolxanthohumol results in increased cleavage of and results in increased activity of CASP7 protein15995977
C488234XCT790manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[XCT790 results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP7 protein]19464277
C488234XCT790[XCT790 results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP7 protein19464277
C063449zileutonPalmitic Acid promotes the reaction [zileuton results in increased activity of CASP7 protein]22700542
C063449zileutonzileuton results in increased activity of CASP7 protein22700542
D015032Zinc"Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of CASP7 protein]"21239534
C016837zinc chloride"[zinc chloride co-treated with pyrithione] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of CASP7 protein]"21239534
C097270ZM 241385ZM 241385 inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]24704558
C088658zoledronic acid[Tretinoin co-treated with zoledronic acid] results in increased activity of CASP7 protein20349282
C088658zoledronic acid[zoledronic acid co-treated with Gossypol] results in increased activity of CASP7 protein19825521
C088658zoledronic acidzoledronic acid results in increased activity of CASP7 protein19825521

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004197cysteine-type endopeptidase activity-TAS-  
GO:0005515protein binding-IPI9525868  11084335  11257230  11257231  12888622  21157428  
21555521  25416956  
GO:0008233peptidase activity-IDA19740745  
GO:0008234cysteine-type peptidase activity-TAS8567622  
GO:0097153cysteine-type endopeptidase activity involved in apoptotic process-IBA21873635  
GO:0097200cysteine-type endopeptidase activity involved in execution phase of apoptosis-IMP22253444  
GO ID GO Term Qualifier Evidence PubMed
GO:0006508proteolysis-IDA12888622  
GO:0006915apoptotic process-IBA21873635  
GO:0006915apoptotic process-IDA17464193  
GO:0072734cellular response to staurosporine-IMP22253444  
GO:0097194execution phase of apoptosis-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA17167422  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IBA21873635  
GO:0005737cytoplasm-TAS8576161  
GO:0005829cytosol-IDA17167422  
GO:0005829cytosol-TAS-  
KEGG ID KEGG Term
hsa04210Apoptosis
hsa05010Alzheimer's disease
Reactome ID Reactome Term Evidence
R-HSA-109581ApoptosisTAS
R-HSA-109606Intrinsic Pathway for ApoptosisTAS
R-HSA-111459Activation of caspases through apoptosome-mediated cleavageTAS
R-HSA-111461Cytochrome c-mediated apoptotic responseTAS
R-HSA-111463SMAC binds to IAPs TAS
R-HSA-111464SMAC-mediated dissociation of IAP:caspase complexes TAS
R-HSA-111465Apoptotic cleavage of cellular proteinsTAS
R-HSA-111469SMAC-mediated apoptotic responseTAS
R-HSA-111471Apoptotic factor-mediated responseTAS
R-HSA-264870Caspase-mediated cleavage of cytoskeletal proteinsTAS
R-HSA-5357801Programmed Cell DeathTAS
R-HSA-75153Apoptotic execution phaseTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
21212151Interactions between genetic polymorphisms in the apoptotic pathway and environmental factors on esophageal adenocarcinoma risk. (2011 Apr)Wu ICCarcinogenesis