Gene: YIPF4

84272
FinGER4|Nbla11189
Yip1 domain family member 4
protein-coding
2p22.3
Ensembl:ENSG00000119820 MIM:617534 Vega:OTTHUMG00000128452 UniprotKB:Q9BSR8
NC_000002.12
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.563e-1 (AD)  4.756e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MBNL20.917
APPBP20.912
PUM10.91
FBXL30.902
CGGBP10.898
KPNA30.896
RAB2B0.896
SLC35A50.895
COPS20.893
FAM8A10.893

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.647
OR4F29-0.6
CSAG1-0.31
KLRB1-0.292
TFPI2-0.288
MS4A1-0.276
FZD10-0.276
TBX21-0.276
CLEC6A-0.266
KLRF1-0.26

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[PIK3CA gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in increased expression of YIPF4 mRNA"20453058
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of YIPF4 mRNA19770486
D001280AtrazineAtrazine results in increased expression of YIPF4 mRNA23358194
C006780bisphenol Abisphenol A affects the expression of YIPF4 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of YIPF4 mRNA25181051
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of YIPF4 mRNA23650126
D019327Copper SulfateCopper Sulfate results in decreased expression of YIPF4 mRNA19549813
D016572CyclosporineCyclosporine results in increased expression of YIPF4 mRNA25562108|2798913
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene affects the expression of YIPF4 mRNA"26496743
C000944dicrotophosdicrotophos results in decreased expression of YIPF4 mRNA28302478
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of YIPF4 mRNA22079256
D005897GlafenineGlafenine results in decreased expression of YIPF4 mRNA24136188
D017313FenretinideFenretinide results in decreased expression of YIPF4 mRNA28973697
D006861Hydrogen Peroxide[Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of YIPF4 protein18951874
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of YIPF4 mRNA18951874
C544151jinfukangjinfukang results in decreased expression of YIPF4 mRNA27392435
C410337K 7174K 7174 results in increased expression of YIPF4 mRNA24086573
D048628KetolidesKetolides analog results in decreased expression of YIPF4 mRNA24967691
C045463leflunomideleflunomide results in increased expression of YIPF4 mRNA28988120
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of YIPF4 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of YIPF4 mRNA"25554681
C051752nefazodonenefazodone results in increased expression of YIPF4 mRNA24136188
D009538NicotineNicotine results in decreased expression of YIPF4 mRNA17997037
D010100OxygenOxygen deficiency results in increased expression of YIPF4 mRNA22629407
D010100OxygenOxygen inhibits the reaction [Oxygen deficiency results in increased expression of YIPF4 mRNA]22629407
D010936Plant ExtractsPlant Extracts results in increased expression of YIPF4 mRNA23557933
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of YIPF4 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of YIPF4 mRNA22079256
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of YIPF4 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of YIPF4 mRNA21215274
D013806Theophylline[Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of YIPF4 protein18951874
D013893ThiramThiram results in increased expression of YIPF4 mRNA20530235
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of YIPF4 mRNA20133372
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of YIPF4 mRNA"26179874
D014635Valproic AcidValproic Acid results in increased expression of YIPF4 mRNA29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI16189514  25416956  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005783endoplasmic reticulum-IDA-  
GO:0005794Golgi apparatus-IDA-  
GO:0005886plasma membrane-IDA-  
GO:0016021integral component of membrane-IEA-  
GO:0043231intracellular membrane-bounded organelle-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29212247A six-mRNA signature model for the prognosis of head and neck squamous cell carcinoma. (2017 Nov 7)Guo WOncotarget