Gene: BRMS1L

84312
BRMS1
BRMS1 like transcriptional repressor
protein-coding
14q13.2
Ensembl:ENSG00000100916 Vega:OTTHUMG00000170559 UniprotKB:Q5PSV4
NC_000014.9
PubMed
0   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.815e-1 (AD)  2.328e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC25A460.945
SLC30A90.944
G3BP20.941
TRUB10.941
VTA10.94
RAD10.939
ERLEC10.938
BTF3L40.938
KRAS0.938
ADSS0.938

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.512
CSAG1-0.477
OR4F29-0.472
SYDE1-0.401
EVC2-0.396
MTRNR2L10-0.395
CDA-0.391
MAGEA12-0.39
ANPEP-0.39
HVCN1-0.372

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of BRMS1L mRNA"23146750
D000082AcetaminophenAcetaminophen results in increased expression of BRMS1L mRNA22230336
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of BRMS1L mRNA21641981
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of BRMS1L mRNA24449571
D001280AtrazineAtrazine results in increased expression of BRMS1L mRNA25929836
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BRMS1L mRNA22316170|2623829
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of BRMS1L mRNA"19150397
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of BRMS1L mRNA"26238291
D004958EstradiolEstradiol results in decreased expression of BRMS1L mRNA17823450
C006780bisphenol Abisphenol A affects the expression of BRMS1L mRNA25181051
D003687DehydroepiandrosteroneDehydroepiandrosterone results in decreased expression of BRMS1L mRNA17823450
D003703DemecolcineDemecolcine results in increased expression of BRMS1L mRNA23649840
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of BRMS1L mRNA21266533
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of BRMS1L mRNA27392435
D002945CisplatinCisplatin results in increased expression of BRMS1L mRNA27392435
C000944dicrotophosdicrotophos results in decreased expression of BRMS1L mRNA28302478
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of BRMS1L mRNA17823450
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of BRMS1L mRNA23649840
D005557FormaldehydeFormaldehyde results in increased expression of BRMS1L mRNA23649840
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of BRMS1L mRNA27392435
C544151jinfukangjinfukang results in decreased expression of BRMS1L mRNA27392435
C045463leflunomideleflunomide results in decreased expression of BRMS1L mRNA28988120
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of BRMS1L mRNA23649840
C028007nickel monoxidenickel monoxide results in increased expression of BRMS1L mRNA19167457
D010047Ovalbumin[Ovalbumin affects the susceptibility to Particulate Matter] which results in decreased expression of BRMS1L mRNA19176365
D052638Particulate Matter[Ovalbumin affects the susceptibility to Particulate Matter] which results in decreased expression of BRMS1L mRNA19176365
D010416PentachlorophenolPentachlorophenol results in increased expression of BRMS1L mRNA23892564
D011374ProgesteroneProgesterone results in increased expression of BRMS1L mRNA19690047
D012822Silicon DioxideSilicon Dioxide results in increased expression of BRMS1L mRNA22431001
C017947sodium arsenitesodium arsenite results in increased expression of BRMS1L mRNA22700541
D012999SomanSoman results in decreased expression of BRMS1L mRNA19281266
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BRMS1L mRNA"26179874
D014520UrethaneUrethane results in increased expression of BRMS1L mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of BRMS1L mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of BRMS1L mRNA23179753
C111237vorinostatvorinostat results in increased expression of BRMS1L mRNA27188386

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004407histone deacetylase activityCONTRIBUTES_TOIBA21873635  
GO:0005515protein binding-IPI25416956  
GO:0042826histone deacetylase binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IBA21873635  
GO:0006351transcription, DNA-templated-IEA-  
GO:0016575histone deacetylation-IBA21873635  
GO:0040008regulation of growth-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0070822Sin3-type complex-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal