Gene: HDGFL2

84717
HDGF-2|HDGF2|HDGFRP2|HRP-2|HRP2
HDGF like 2
protein-coding
19p13.3
Ensembl:ENSG00000167674 MIM:617884 Vega:OTTHUMG00000182007 UniprotKB:Q7Z4V5
NC_000019.10
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.228e-1 (AD)  4.837e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs16992410chr19:4487809 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of HDGFL2 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of HDGFL2 mRNA"21346803
C5724913-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol results in decreased expression of HDGFL2 protein26194647
D000643Ammonium ChlorideAmmonium Chloride affects the expression of HDGFL2 mRNA16483693
C006780bisphenol Abisphenol A results in increased expression of HDGFL2 mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of HDGFL2 protein24552547
D002994ClofibrateClofibrate results in decreased expression of HDGFL2 mRNA23811191
C014347decitabinedecitabine results in increased expression of HDGFL2 mRNA15251184
C014347decitabine[Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of HDGFL2 mRNA15251184
D004026DieldrinDieldrin results in decreased expression of HDGFL2 mRNA28385952
C010974glyphosate[Surface-Active Agents co-treated with glyphosate] results in increased expression of HDGFL2 mRNA22467014
C010176halofuginonehalofuginone results in increased expression of HDGFL2 mRNA17180598
C544151jinfukangjinfukang results in increased expression of HDGFL2 mRNA27392435
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of HDGFL2 mRNA"24972896
D010656PhenylephrinePhenylephrine results in decreased expression of HDGFL2 mRNA18158353
D011748PyrogallolPyrogallol results in increased expression of HDGFL2 mRNA20362636
C059514resveratrolresveratrol results in decreased expression of HDGFL2 protein25505154
D013501Surface-Active Agents[Surface-Active Agents co-treated with glyphosate] results in increased expression of HDGFL2 mRNA22467014
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of HDGFL2 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of HDGFL2 mRNA15251184
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of HDGFL2 mRNA26232522
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of HDGFL2 protein16548065
D013893ThiramThiram results in decreased expression of HDGFL2 mRNA20530235
C012589trichostatin Atrichostatin A affects the expression of HDGFL2 mRNA28542535
D014635Valproic AcidValproic Acid results in increased methylation of HDGFL2 gene29154799
D014635Valproic AcidValproic Acid affects the expression of HDGFL2 mRNA17292431
D014635Valproic AcidValproic Acid results in increased expression of HDGFL2 mRNA20546886
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of HDGFL2 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003682chromatin binding-IEA-  
GO:0005515protein binding-IPI17353931  17620599  21044950  25689719  
GO ID GO Term Qualifier Evidence PubMed
GO:0030307positive regulation of cell growth-IMP25689719  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal