Gene: CGGBP1

8545
CGGBP|p20-CGGBP
CGG triplet repeat binding protein 1
protein-coding
3p11.1
Ensembl:ENSG00000163320 MIM:603363 Vega:OTTHUMG00000159009 UniprotKB:Q9UFW8
NC_000003.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  2.614e-1 (ND)   (Frontal_Cortex)
8.552e-1 (AD)  8.250e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs12629581chr3:88122078 (GRCh38.p7)A>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
COPS20.948
NUS10.942
APPL10.938
KPNA30.936
USO10.934
CAPRIN10.932
ATF20.932
API50.932
YTHDF30.932
C5orf240.931

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.661
OR4F29-0.62
S100A14-0.243
NXNL1-0.242
PTGDR2-0.23
CSAG1-0.229
KLRB1-0.22
KCNK5-0.218
S100A1-0.217
MTRNR2L10-0.212

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane affects the expression of CGGBP1 mRNA"18648102
D000082AcetaminophenAcetaminophen results in increased expression of CGGBP1 mRNA21420995
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CGGBP1 mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CGGBP1 mRNA22228805
C044887beta-methylcholinebeta-methylcholine affects the expression of CGGBP1 mRNA21179406
C006780bisphenol Abisphenol A results in increased expression of CGGBP1 mRNA25181051
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CGGBP1 gene20938992
C018021cobaltous chloridecobaltous chloride results in decreased expression of CGGBP1 mRNA19320972
D019327Copper SulfateCopper Sulfate results in decreased expression of CGGBP1 mRNA19549813
D016572CyclosporineCyclosporine results in decreased expression of CGGBP1 mRNA25562108
C093628cyproconazolecyproconazole results in decreased expression of CGGBP1 mRNA22334560
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of CGGBP1 mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of CGGBP1 mRNA21266533
D002945CisplatinCisplatin results in increased phosphorylation of CGGBP1 protein22006019
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of CGGBP1 protein23301498
C109476epoxiconazoleepoxiconazole results in decreased expression of CGGBP1 mRNA22334560
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of CGGBP1 mRNA23649840
D005485FlutamideFlutamide results in increased expression of CGGBP1 mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CGGBP1 gene20938992
D005557FormaldehydeFormaldehyde results in increased expression of CGGBP1 mRNA23649840
D005839GentamicinsGentamicins results in increased expression of CGGBP1 mRNA22061828
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of CGGBP1 mRNA22634610
C544151jinfukangjinfukang results in decreased expression of CGGBP1 mRNA27392435
C410337K 7174K 7174 results in increased expression of CGGBP1 mRNA24086573
D008694MethamphetamineMethamphetamine results in increased expression of CGGBP1 mRNA19564919
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CGGBP1 gene20938992
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of CGGBP1 mRNA23649840
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of CGGBP1 mRNA"25620056
C006253pirinixic acidpirinixic acid results in decreased expression of CGGBP1 mRNA18445702
D010936Plant ExtractsPlant Extracts results in increased expression of CGGBP1 mRNA23557933
C045950propiconazolepropiconazole results in decreased expression of CGGBP1 mRNA22334560
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CGGBP1 mRNA21570461
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of CGGBP1 mRNA20133372
D017974Uranium CompoundsUranium Compounds results in decreased expression of CGGBP1 mRNA19654044
D014635Valproic AcidValproic Acid affects the expression of CGGBP1 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of CGGBP1 mRNA23179753
D001335Vehicle EmissionsVehicle Emissions affects the methylation of CGGBP1 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding-IBA21873635  
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding-IMP10692448  
GO:0001227transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding-IBA21873635  
GO:0001227transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding-IDA10692448  
GO:0001227transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding-IMP10692448  
GO:0003690double-stranded DNA binding-TAS8626781  
GO:0005515protein binding-IPI25416956  29426014  
GO:0042802identical protein binding-IPI25416956  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IBA21873635  
GO:0000122negative regulation of transcription by RNA polymerase II-IDA10692448  
GO:0006351transcription, DNA-templated-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA-  
GO:0005654nucleoplasm-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal