Gene: RUNX2

860
AML3|CBF-alpha-1|CBFA1|CCD|CCD1|CLCD|OSF-2|OSF2|PEA2aA|PEBP2aA
runt related transcription factor 2
protein-coding
6p21.1
Ensembl:ENSG00000124813 MIM:600211 Vega:OTTHUMG00000014774 UniprotKB:Q13950
NG_008020.1
PubMed|SNP Mapped
ND|AD
8   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.558e-1 (AD)  3.350e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs1321075chr6:45424206 (GRCh38.p7)T>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ARHGAP90.687
SSH20.68
MANBA0.674
GMIP0.673
THEMIS20.672
SRGAP20.655
ATM0.65
SIRPB20.644
LPAR20.643
ADAM280.642

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
HES5-0.331
DIO2-0.32
LYPD1-0.259
SLC22A6-0.259
OR4F5-0.257
ARSF-0.256
TNNT1-0.256
WNT7B-0.252
OR4F29-0.241
BTBD17-0.239

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of RUNX2 mRNA"12021203
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein]21910061
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid inhibits the reaction [RUNX2 protein results in increased expression of ALPL mRNA]21910061
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid inhibits the reaction [RUNX2 protein results in increased expression of BGLAP mRNA]21910061
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[PIK3CA gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in increased expression of RUNX2 mRNA"20453058
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of RUNX2 mRNA"25510870
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of RUNX2 mRNA"23829299
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased expression of RUNX2 mRNA]17689939
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of RUNX2 mRNA17689939
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenic trioxide results in decreased expression of RUNX2]24531206
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA]26053266|2613693
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one[pyrazolanthrone co-treated with SB 203580 co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA]26136938
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of RUNX2 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of RUNX2 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of RUNX2 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of RUNX2 mRNA"25510870
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RUNX2 mRNA]23625689
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased expression of RUNX2 mRNA23625689
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA]26053266
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein]"20458730
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Bezafibrate results in increased expression of RUNX2 mRNA]"21499286
D000082AcetaminophenAcetaminophen results in increased expression of RUNX2 mRNA29067470
C056165acetovanilloneacetovanillone inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]24080574
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of RUNX2 mRNA]19017541
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Dexamethasone affects the expression of RUNX2 mRNA]24239970
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of RUNX2 gene27153756
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in decreased expression of RUNX2 mRNA28522335
C010845aluminum chloride[Sodium Fluoride co-treated with aluminum chloride] results in increased expression of RUNX2 mRNA21560300
C010845aluminum chloridealuminum chloride results in decreased expression of RUNX2 mRNA27470910
C010845aluminum chlorideginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of RUNX2 mRNA]27470910
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid affects the expression of RUNX2 mRNA24098073
D000643Ammonium ChlorideAmmonium Chloride affects the expression of RUNX2 mRNA16483693
C088115anacardic acidanacardic acid inhibits the reaction [Tretinoin results in increased expression of RUNX2 mRNA]24819975
D001151ArsenicArsenic affects the methylation of RUNX2 gene25304211
C006632arsenic trioxidearsenic trioxide results in decreased expression of RUNX2 mRNA20458559
C006632arsenic trioxide2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenic trioxide results in decreased expression of RUNX2]24531206
C006632arsenic trioxidearsenic trioxide results in decreased expression of RUNX224531206
C006632arsenic trioxidearsenic trioxide results in decreased expression of RUNX2 mRNA22465848
C015001arsenitearsenite results in increased methylation of RUNX2 promoter23974009
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of RUNX2 mRNA"18687144
D001205Ascorbic Acid[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA26424790
D001205Ascorbic AcidAscorbic Acid results in increased expression of RUNX2 mRNA28105418
D001205Ascorbic Acid[Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA17692823
D001205Ascorbic AcidEZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]26424790
D001205Ascorbic AcidAscorbic Acid results in increased expression of RUNX2 mRNA20530736
D001205Ascorbic AcidU 0126 inhibits the reaction [Ascorbic Acid results in increased expression of RUNX2 mRNA]20530736
D001205Ascorbic Acid[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein27387537
D001205Ascorbic Acid[Ascorbic Acid co-treated with Phosphates] results in increased expression of RUNX2 mRNA21613385
D001205Ascorbic Acid[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA27028516
D001205Ascorbic AcidDexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]27387537
D001205Ascorbic Acidginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]27387537
D001205Ascorbic AcidHydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]27028516
D001205Ascorbic AcidNOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]]27387537
D001205Ascorbic AcidQuercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]]27028516
D001205Ascorbic Acid[Ascorbic Acid co-treated with IL11 protein] results in increased expression of RUNX2 mRNA17956465
D001205Ascorbic AcidAscorbic Acid results in increased expression of RUNX2 mRNA17274723
C547126AZM551248AZM551248 results in increased expression of RUNX2 mRNA22323515
D001554BenzeneBenzene results in increased expression of RUNX2 mRNA22960397
D001554BenzeneBenzene results in decreased expression of RUNX2 mRNA15120971
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of RUNX2 mRNA"20382639
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RUNX2 mRNA"19150397
D001599BerberineBerberine results in increased expression of RUNX2 mRNA26478571
D001599BerberineCTNNB1 mutant form inhibits the reaction [Berberine results in increased expression of RUNX2 mRNA]26478571
D001599BerberineDKK1 protein inhibits the reaction [Berberine results in increased expression of RUNX2 mRNA]26478571
D004958EstradiolEGF protein promotes the reaction [Estradiol results in increased expression of RUNX2 mRNA]24758408
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of RUNX2 mRNA20660070
D004958EstradiolEstradiol results in increased expression of RUNX2 mRNA16202921|1768993
D004958Estradiolfulvestrant inhibits the reaction [Estradiol results in increased expression of RUNX2 mRNA]17689939
D004958EstradiolEstradiol affects the expression of RUNX2 mRNA17166402
C031463beta-glycerophosphoric acid[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA26424790
C031463beta-glycerophosphoric acid[Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA17692823
C031463beta-glycerophosphoric acidEZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]26424790
C031463beta-glycerophosphoric acid[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein27387537
C031463beta-glycerophosphoric acid[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA27028516
C031463beta-glycerophosphoric acidDexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]27387537
C031463beta-glycerophosphoric acidginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]27387537
C031463beta-glycerophosphoric acidHydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]27028516
C031463beta-glycerophosphoric acidNOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]]27387537
C031463beta-glycerophosphoric acidQuercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]]27028516
D001629Bezafibrate"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Bezafibrate results in increased expression of RUNX2 mRNA]"21499286
D001629BezafibrateBezafibrate results in increased expression of RUNX2 mRNA21499286
D001629BezafibrateGSK0660 inhibits the reaction [Bezafibrate results in increased expression of RUNX2 mRNA]21499286
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA]12403780
C006780bisphenol Abisphenol A affects the methylation of RUNX2 promoter27334623
C006780bisphenol Abisphenol A results in decreased expression of RUNX2 mRNA23900028
C006780bisphenol Abisphenol A results in decreased expression of RUNX2 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of RUNX2 gene28505145
C032688boric acidboric acid affects the expression of RUNX2 mRNA24704097
D000069286BortezomibBortezomib results in increased expression of RUNX2 protein19894220
C038091butylparabenbutylparaben results in decreased expression of RUNX2 mRNA28527915
D002104CadmiumCadmium results in decreased expression of RUNX2 mRNA20570719
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of RUNX2 mRNA]19017541
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of RUNX222019892
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of RUNX2 mRNA19017541|2559613
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 protein]28363435
C058819calphostin Ccalphostin C inhibits the reaction [FGF2 protein results in increased expression of and results in increased activity of RUNX2 protein]12403780
C058819calphostin Ccalphostin C inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA]12403780
D002164CamphorCamphor analog affects the expression of RUNX2 mRNA24704097
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of RUNX2 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of RUNX2 mRNA17334410
D002251Carbon TetrachlorideFR 167653 inhibits the reaction [Carbon Tetrachloride results in increased expression of RUNX2 mRNA]17334410
D000068579Celecoxib[Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 mRNA27050768
D000068579Celecoxib[Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 protein27050768
D048271ChitosanChitosan results in increased expression of RUNX2 mRNA25246786
D048271ChitosanChitosan results in increased expression of RUNX2 protein25246786
C004656chloroacetaldehydechloroacetaldehyde results in decreased expression of RUNX2 mRNA25596134
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RUNX2 mRNA20938992
C022990chromic chloride[cobaltous chloride co-treated with chromic chloride] affects the expression of RUNX2 mRNA25966675
D002858Chromium AlloysChromium Alloys results in decreased expression of RUNX2 mRNA25966675
C059262cidofovircidofovir results in increased expression of RUNX2 mRNA25596134
D004002Clodronic AcidClodronic Acid results in increased expression of RUNX2 mRNA25596134
C007095cobaltiprotoporphyrin[cobaltiprotoporphyrin co-treated with IL1B protein] results in increased expression of RUNX2 mRNA22155307
C018021cobaltous chloridecobaltous chloride affects the expression of RUNX2 mRNA25966675
C018021cobaltous chloride[cobaltous chloride co-treated with chromic chloride] affects the expression of RUNX2 mRNA25966675
C018021cobaltous chloridecobaltous chloride results in decreased expression of RUNX2 mRNA16772336
D005576ColforsinColforsin results in increased expression of RUNX2 mRNA20197312
D003300Copper[Copper co-treated with Dietary Sucrose] results in increased expression of RUNX2 mRNA26033743
D003300CopperCopper deficiency results in increased expression of RUNX2 mRNA26033743
D065366Cryptoxanthins[Cryptoxanthins co-treated with Vitamin A] results in increased expression of RUNX2 mRNA15962303
D065366CryptoxanthinsCryptoxanthins results in increased expression of RUNX2 mRNA15962303
D065366CryptoxanthinsCycloheximide inhibits the reaction [Cryptoxanthins results in increased expression of RUNX2 mRNA]15962303
D065366CryptoxanthinsDichlororibofuranosylbenzimidazole inhibits the reaction [Cryptoxanthins results in increased expression of RUNX2 mRNA]15962303
D003474CurcuminCurcumin results in decreased expression of RUNX2 protein15129424
D003513CycloheximideCycloheximide inhibits the reaction [Cryptoxanthins results in increased expression of RUNX2 mRNA]15962303
D003513CycloheximideCycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA]18327666
D003634DDTDDT results in increased expression of RUNX2 mRNA25014179
D003676DeferoxamineDeferoxamine results in decreased expression of RUNX2 mRNA16772336
D003907DexamethasoneDexamethasone results in increased expression of RUNX2 mRNA25286332|2646816
D003907Dexamethasone[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA26424790
D003907DexamethasoneDexamethasone results in decreased expression of RUNX2 mRNA25047013
D003907DexamethasoneEZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]26424790
D003907DexamethasoneAcetylcysteine inhibits the reaction [Dexamethasone affects the expression of RUNX2 mRNA]24239970
D003907Dexamethasone[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA27028516
D003907Dexamethasonecaffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 protein]28363435
D003907DexamethasoneDexamethasone affects the expression of RUNX2 mRNA24239970
D003907DexamethasoneDexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]27387537
D003907DexamethasoneDexamethasone results in decreased expression of RUNX2 mRNA27387537
D003907DexamethasoneDexamethasone results in decreased expression of RUNX2 protein27387537|2836343
D003907Dexamethasoneginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]27387537
D003907Dexamethasoneginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 mRNA]27387537
D003907Dexamethasoneginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 protein]27387537
D003907DexamethasoneHydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]27028516
D003907DexamethasoneNOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]]27387537
D003907DexamethasoneQuercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]]27028516
D002945CisplatinCisplatin affects the expression of RUNX2 mRNA25596134
D002945CisplatinCisplatin promotes the reaction [jinfukang results in decreased expression of RUNX2 mRNA]27392435
D002945CisplatinCisplatin results in decreased expression of RUNX2 mRNA27392435
D002945Cisplatinjinfukang promotes the reaction [Cisplatin results in decreased expression of RUNX2 mRNA]27392435
D004004DichlororibofuranosylbenzimidazoleDichlororibofuranosylbenzimidazole inhibits the reaction [Cryptoxanthins results in increased expression of RUNX2 mRNA]15962303
D004004DichlororibofuranosylbenzimidazoleDichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA]18327666
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of RUNX2 mRNA26924002
D019422Dietary Sucrose[Copper co-treated with Dietary Sucrose] results in increased expression of RUNX2 mRNA26033743
D019422Dietary SucroseDietary Sucrose results in increased expression of RUNX2 mRNA26033743
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of RUNX2 protein22985736
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of RUNX2 mRNA24535843
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RUNX2 mRNA22129741
D004075DiglyceridesDiglycerides results in increased expression of RUNX2 mRNA22286232
D002117CalcitriolCalcitriol promotes the reaction [VDR protein binds to RUNX2 enhancer]17293108
D002117CalcitriolCalcitriol results in decreased expression of RUNX2 mRNA16002434|2648566
D002117CalcitriolCalcitriol results in increased expression of RUNX2 mRNA21542014|2810541
D002117CalcitriolCalcitriol results in decreased expression of RUNX2 mRNA17293108
D002117CalcitriolCalcitriol results in increased expression of RUNX2 protein19092814
C024629dimethyl phthalatedimethyl phthalate affects the expression of RUNX2 mRNA26924002
D004221DisulfiramDisulfiram results in increased expression of RUNX2 mRNA24496638
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of RUNX2 mRNA"16543677
D015118Eicosapentaenoic AcidEicosapentaenoic Acid results in decreased expression of RUNX2 mRNA21193197
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of RUNX2 mRNA22079256
D004967EstrogensEstrogens results in increased expression of RUNX2 mRNA25014179
D004967EstrogensEstrogens affects the expression of RUNX2 mRNA24098073
D000431Ethanol[Genistein co-treated with Ethanol] results in increased expression of RUNX2 mRNA24872432
D000431Ethanol[Genistein co-treated with Ethanol] results in increased expression of RUNX2 protein24872432
C034096ethoxyacetic acidethoxyacetic acid affects the expression of RUNX2 mRNA24704097
C004808farnesyl pyrophosphatefarnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]18310456
D005419FlavonoidsFlavonoids results in increased expression of RUNX2 mRNA16543677|2323899
D005459FluoridesFluorides results in increased expression of RUNX2 mRNA20709135
D005459FluoridesFluorides inhibits the reaction [potassium phosphate results in increased expression of RUNX2 mRNA]24561004
D005472FluorouracilFluorouracil affects the expression of RUNX2 mRNA24704097
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RUNX2 mRNA20938992
C104334FR 167653FR 167653 inhibits the reaction [Carbon Tetrachloride results in increased expression of RUNX2 mRNA]17334410
C069837fullerene C60fullerene C60 results in increased expression of RUNX2 mRNA19167457
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol results in increased expression of RUNX2 mRNA]17689939
C070081fulvestrantfulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of RUNX2 mRNA]26362186
C070081fulvestrantfulvestrant inhibits the reaction [resveratrol results in increased expression of RUNX2 mRNA]17689939
C070081fulvestrantfulvestrant inhibits the reaction [naringin results in increased expression of RUNX2 mRNA]23596885
C057580gallocatecholgallocatechol results in increased expression of RUNX2 mRNA21877759
C013172gamma-oryzanolgamma-oryzanol affects the expression of RUNX2 mRNA24098073
D019833GenisteinGenistein affects the expression of RUNX2 mRNA17166402
D019833Genistein[Genistein co-treated with Ethanol] results in increased expression of RUNX2 mRNA24872432
D019833Genistein[Genistein co-treated with Ethanol] results in increased expression of RUNX2 protein24872432
D019833GenisteinGenistein results in increased expression of RUNX2 mRNA24872432
D019833GenisteinGenistein results in increased expression of RUNX2 protein24872432
D019833GenisteinGenistein results in increased expression of RUNX2 mRNA21877759
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]18310456
C112485ginkgolic acidginkgolic acid inhibits the reaction [Tretinoin results in increased expression of RUNX2 mRNA]24819975
C442759ginsenoside Rb1ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of RUNX2 mRNA]27470910
C442759ginsenoside Rb1ginsenoside Rb1 results in increased expression of RUNX2 mRNA27470910
C097367ginsenoside Rg3ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]27387537
C097367ginsenoside Rg3ginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 mRNA]27387537
C097367ginsenoside Rg3ginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of RUNX2 protein]27387537
C097367ginsenoside Rg3NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]]27387537
D005944Glucosamine"4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein]"20458730
D005944GlucosamineGlucosamine analog results in increased expression of RUNX2 mRNA20458730
D005944GlucosamineGlucosamine analog results in increased phosphorylation of RUNX2 protein20458730
D005947GlucoseGlucose results in increased expression of RUNX2 mRNA17178593
D005960GlucosidesGlucosides analog affects the expression of RUNX2 mRNA24098073
C004312glycidolglycidol results in increased expression of RUNX2 mRNA24915197
C529769GSK0660GSK0660 inhibits the reaction [Bezafibrate results in increased expression of RUNX2 mRNA]21499286
C577920GSK126GSK126 results in increased expression of RUNX2 mRNA26424790
C409722hexaconazolehexaconazole affects the expression of RUNX2 mRNA24704097
D006851Hydrochloric AcidHydrochloric Acid results in increased expression of RUNX2 mRNA17183249
D006851Hydrochloric AcidHydrochloric Acid results in increased expression of RUNX2 protein17183249
D006861Hydrogen PeroxideDKK1 protein inhibits the reaction [naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]]26482937
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of RUNX2 mRNA26482937
D006861Hydrogen Peroxidenaringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]26482937
D006861Hydrogen PeroxideHydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]27028516
D006861Hydrogen PeroxideQuercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]]27028516
C031927hydroquinonehydroquinone results in increased expression of RUNX2 mRNA22960397
D002112CalcifediolCalcifediol results in increased expression of RUNX2 mRNA21542014
D002112CalcifediolCYP27B1 protein promotes the reaction [Calcifediol results in increased expression of RUNX2 mRNA]21542014
D002112CalcifediolKetoconazole inhibits the reaction [Calcifediol results in increased expression of RUNX2 mRNA]21542014
D006918HydroxyureaHydroxyurea affects the expression of RUNX2 mRNA24704097
C056599icariinicariin results in increased expression of RUNX2 mRNA18295595|1974780
C056599icariinNOG protein inhibits the reaction [icariin results in increased expression of RUNX2 mRNA]18295595|1974780
C056599icariinicariin results in increased expression of RUNX2 mRNA20019778
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RUNX2 mRNA22129741
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RUNX2 mRNA25613284
C027681isonicotinamideisonicotinamide results in increased expression of RUNX2 mRNA21745208
C544151jinfukangCisplatin promotes the reaction [jinfukang results in decreased expression of RUNX2 mRNA]27392435
C544151jinfukangjinfukang promotes the reaction [Cisplatin results in decreased expression of RUNX2 mRNA]27392435
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BRD4 protein binds to RUNX2 gene]25944566
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BRD4 protein binds to RUNX2 promoter]25307878
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of RUNX2 mRNA23129625|2464647
C561695(+)-JQ1 compoundRUNX2 mutant form promotes the reaction [(+)-JQ1 compound results in increased expression of CDKN1A protein]25307878
C561695(+)-JQ1 compoundRUNX2 protein inhibits the reaction [(+)-JQ1 compound results in increased expression of CDKN1A protein]25307878
C561695(+)-JQ1 compoundRUNX2 protein results in decreased susceptibility to (+)-JQ1 compound25307878
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of RUNX2 mRNA24646477|2594456
C006552kaempferolkaempferol results in increased expression of RUNX2 mRNA23989061
D007654KetoconazoleKetoconazole inhibits the reaction [Calcifediol results in increased expression of RUNX2 mRNA]21542014
D007854LeadLead results in decreased expression of RUNX2 mRNA23086611
D007854LeadLead results in decreased expression of RUNX2 mRNA23086611
D007854LeadLead results in decreased expression of RUNX2 protein23086611
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 inhibits the reaction [BMP2 protein results in increased expression of RUNX2 protein]"26961602
C482199lipopolysaccharide, E coli O55-B5"MIR23B mRNA inhibits the reaction [lipopolysaccharide, E coli O55-B5 inhibits the reaction [BMP2 protein results in increased expression of RUNX2 protein]]"26961602
D019808LosartanLosartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 mRNA]27412937
D019808LosartanLosartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 protein]27412937
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of RUNX2 mRNA21641980
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of RUNX2 mRNA26378955
D008550MelatoninMelatonin results in increased expression of RUNX2 mRNA20738756
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
D008687MetforminMetformin results in increased expression of RUNX2 protein19594306
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RUNX2 mRNA20938992
D008727MethotrexateRUNX2 mRNA results in decreased susceptibility to Methotrexate20008919
D008731MethoxychlorMethoxychlor results in decreased expression of RUNX2 mRNA23303685
D008731MethoxychlorMethoxychlor results in increased methylation of RUNX2 gene23303685
C015358methylparabenmethylparaben results in decreased expression of RUNX2 mRNA28527915
D015735MifepristoneMifepristone results in decreased expression of RUNX2 mRNA20197312
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in decreased expression of RUNX2 mRNA22401849|2577708
C028577monobutyl phthalatemonobutyl phthalate affects the expression of RUNX2 mRNA24704097
C517284monomethyl phthalatemonomethyl phthalate affects the expression of RUNX2 mRNA26924002
C093875montelukastmontelukast results in increased expression of RUNX2 mRNA19544365
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 mRNA27050768
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 protein27050768
C005274naringinDKK1 protein inhibits the reaction [naringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]]26482937
C005274naringinnaringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of RUNX2 mRNA]26482937
C005274naringinnaringin results in increased expression of RUNX2 mRNA24915843
C005274naringinnaringin results in increased expression of RUNX2 mRNA21741227
C005274naringinfulvestrant inhibits the reaction [naringin results in increased expression of RUNX2 mRNA]23596885
C005274naringinnaringin results in increased expression of RUNX2 mRNA23596885
C553460neoeriocitrinneoeriocitrin results in increased expression of RUNX2 mRNA21741227
C028007nickel monoxidenickel monoxide results in increased expression of RUNX2 mRNA19167457
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"[zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of RUNX2 protein"19913120
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"[zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 mRNA"19913120
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"[zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 protein"19913120
C072936notoginsenoside R1fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of RUNX2 mRNA]26362186
C072936notoginsenoside R1notoginsenoside R1 results in increased expression of RUNX2 mRNA26362186
C510784ormosil[ormosil binds to Polyethylene Glycols] which results in increased expression of RUNX2 mRNA24888373
D010100OxygenOxygen deficiency results in decreased expression of RUNX2 mRNA25596134
D019308Palmitic Acidacetovanillone inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]24080574
D019308Palmitic AcidCYBA mutant form inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]24080574
D019308Palmitic AcidPalmitic Acid results in increased expression of RUNX2 mRNA24080574
D019308Palmitic AcidU 0126 inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]24080574
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of RUNX2 mRNA"25510870
D015232DinoprostoneDinoprostone results in increased expression of RUNX2 mRNA27050768
D015232DinoprostoneDinoprostone results in increased expression of RUNX2 protein27050768
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of RUNX2 mRNA26272509
D010710Phosphates[Ascorbic Acid co-treated with Phosphates] results in increased expression of RUNX2 mRNA21613385
D010710PhosphatesPhosphates results in decreased expression of RUNX2 mRNA26111760
D010936Plant ExtractsPlant Extracts affects the expression of RUNX2 mRNA24098073
C061957polaprezincpolaprezinc results in increased expression of RUNX2 mRNA18327666
D011092Polyethylene Glycols[ormosil binds to Polyethylene Glycols] which results in increased expression of RUNX2 mRNA24888373
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of RUNX2 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of RUNX2 mRNA22079256
C013216potassium phosphateFluorides inhibits the reaction [potassium phosphate results in increased expression of RUNX2 mRNA]24561004
C013216potassium phosphatepotassium phosphate results in increased expression of RUNX2 mRNA24561004
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of RUNX2 mRNA20660070
D015237DinoprostDinoprost results in increased expression of RUNX2 mRNA27050768
D015237DinoprostDinoprost results in increased expression of RUNX2 protein27050768
C432165pyrazolanthrone[pyrazolanthrone co-treated with SB 203580 co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA]26136938
D011794QuercetinQuercetin results in increased expression of RUNX2 mRNA16996034
D011794Quercetin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA]26053266|2613693
D011794Quercetin4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA]26053266
D011794Quercetin[pyrazolanthrone co-treated with SB 203580 co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA]26136938
D011794QuercetinQuercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]]27028516
D011794QuercetinQuercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of RUNX2 mRNA]23117658
D011794QuercetinQuercetin results in increased expression of RUNX2 mRNA17243115|2605326
C004532quinonequinone results in increased expression of RUNX2 mRNA22960397
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride affects the expression of RUNX2 mRNA17166402
C073419RemifeminRemifemin affects the expression of RUNX2 mRNA24098073
C059514resveratrolresveratrol inhibits the reaction [Niacinamide inhibits the reaction [SIRT1 protein binds to RUNX2 protein]]22539994
C059514resveratrolresveratrol inhibits the reaction [Niacinamide results in decreased expression of RUNX2 protein]22539994
C059514resveratrolresveratrol inhibits the reaction [Niacinamide results in increased acetylation of RUNX2 protein]22539994
C059514resveratrolresveratrol inhibits the reaction [TNFSF11 protein results in decreased expression of RUNX2 protein]21239502
C059514resveratrolresveratrol promotes the reaction [[SIRT1 protein binds to EP300 protein] which binds to RUNX2 protein]21239502
C059514resveratrolresveratrol promotes the reaction [SIRT1 protein binds to RUNX2 protein]21239502
C059514resveratrolresveratrol results in decreased acetylation of RUNX2 protein22539994
C059514resveratrol[resveratrol results in increased activity of SIRT1 protein] promotes the reaction [SIRT1 protein binds to RUNX2 protein]22539994
C059514resveratrolresveratrol results in increased expression of RUNX2 protein22539994
C059514resveratrolSIRT1 protein affects the reaction [resveratrol results in decreased acetylation of RUNX2 protein]22539994
C059514resveratrol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased expression of RUNX2 mRNA]17689939
C059514resveratrolfulvestrant inhibits the reaction [resveratrol results in increased expression of RUNX2 mRNA]17689939
C059514resveratrolresveratrol promotes the reaction [[SIRT1 protein binds to FOXO3 protein] which binds to RUNX2 3' UTR]21713995
C059514resveratrolresveratrol promotes the reaction [[[SIRT1 protein binds to FOXO3 protein] which binds to RUNX2 3' UTR] which results in increased expression of RUNX2 mRNA]21713995|2171399
C059514resveratrolresveratrol results in increased expression of RUNX2 mRNA17689939|2171399
C059514resveratrolresveratrol inhibits the reaction [Niacinamide results in decreased expression of RUNX2 protein]22539994
C059514resveratrolresveratrol results in increased expression of RUNX2 mRNA19665018
C059514resveratrolresveratrol results in increased expression of RUNX2 mRNA16813520
C059514resveratrol[resveratrol promotes the reaction [SIRT1 protein binds to RUNX2 protein]] inhibits the reaction [Niacinamide results in increased expression of PPARG]22539994
C059514resveratrol[resveratrol promotes the reaction [SIRT1 protein binds to RUNX2 protein]] which results in decreased activity of NCOR1 protein22539994
C059514resveratrol[resveratrol results in decreased acetylation of RUNX2 protein] inhibits the reaction [Niacinamide results in increased expression of PPARG]22539994
C059514resveratrol[resveratrol results in decreased acetylation of RUNX2 protein] which affects the activity of NCOR1 protein22539994
C009172rhodiolosiderhodioloside results in increased activity of RUNX2 protein24055767
C009172rhodiolosiderhodioloside results in increased expression of RUNX2 mRNA24055767
C089730rosiglitazonerosiglitazone results in decreased expression of RUNX217993761
C089730rosiglitazonerosiglitazone results in decreased expression of RUNX2 mRNA12021203|1450057
C089730rosiglitazonerosiglitazone results in increased expression of RUNX2 mRNA15591153
C085746rottlerinrottlerin inhibits the reaction [FGF2 protein results in increased activity of RUNX2 protein]12403780
C085746rottlerinrottlerin inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA]12403780
C093642SB 203580[pyrazolanthrone co-treated with SB 203580 co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] inhibits the reaction [Quercetin results in increased expression of RUNX2 mRNA]26136938
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of RUNX2 mRNA25895662
D019821SimvastatinSimvastatin results in increased expression of RUNX220381859
D019821SimvastatinDKK1 inhibits the reaction [Simvastatin results in increased expression of RUNX2 mRNA]22058016
D019821Simvastatinfarnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]18310456
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]18310456
D019821SimvastatinSimvastatin inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]18310456
D019821SimvastatinSimvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]18310456
D019821SimvastatinSimvastatin results in increased expression of RUNX2 mRNA20417880|2205801
C017947sodium arsenitesodium arsenite results in decreased expression of RUNX2 mRNA28206643
D012969Sodium FluorideSodium Fluoride results in decreased expression of RUNX2 mRNA26339601
D012969Sodium Fluoride[Sodium Fluoride co-treated with aluminum chloride] results in increased expression of RUNX2 mRNA21560300
D012969Sodium FluorideDKK1 protein inhibits the reaction [Sodium Fluoride results in increased expression of RUNX2 mRNA]24300170
D012969Sodium FluorideDKK1 protein inhibits the reaction [Sodium Fluoride results in increased expression of RUNX2 protein]24300170
D012969Sodium FluorideSodium Fluoride affects the expression of RUNX2 mRNA25132241
D012969Sodium FluorideSodium Fluoride results in increased expression of RUNX2 mRNA24300170
D012969Sodium FluorideSodium Fluoride results in increased expression of RUNX2 protein24300170
D053260SootSoot results in decreased expression of RUNX2 mRNA23634900
D013311StreptozocinStreptozocin results in decreased expression of RUNX2 mRNA25617479
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of RUNX2 mRNA21641980
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of RUNX2 mRNA26378955
C446685systhanesysthane affects the expression of RUNX2 mRNA24704097
D016559TacrolimusTacrolimus results in decreased expression of RUNX2 mRNA15780950
C061133tamibarotenetamibarotene results in decreased expression of RUNX2 mRNA15498508
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of RUNX2 mRNA25777084
D013749Tetrachlorodibenzodioxin2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RUNX2 mRNA]23625689
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of RUNX2 mRNA22903824|2362568
D013749TetrachlorodibenzodioxinAHR protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of RUNX2 mRNA]19264158
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of RUNX2 mRNA24704097
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to RUNX2 gene]20819909
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of RUNX2 mRNA19264158|2405805
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of RUNX2 mRNA17586704|2081990
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of RUNX2 mRNA28077779
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of RUNX2 mRNA19201780|1926415
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of RUNX2 mRNA27913140
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RUNX2 mRNA25613284
D013893ThiramThiram results in decreased expression of RUNX2 mRNA24235232
D013893ThiramVEGFA protein affects the reaction [Thiram results in decreased expression of RUNX2 mRNA]24235232
D013928Thromboxane A2Thromboxane A2 results in increased expression of RUNX2 mRNA27050768
D013928Thromboxane A2Thromboxane A2 results in increased expression of RUNX2 protein27050768
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of RUNX2 mRNA18087596
D014212Tretinoinanacardic acid inhibits the reaction [Tretinoin results in increased expression of RUNX2 mRNA]24819975
D014212Tretinoinginkgolic acid inhibits the reaction [Tretinoin results in increased expression of RUNX2 mRNA]24819975
D014212TretinoinTretinoin results in decreased expression of RUNX2 mRNA15498508
D014212TretinoinTretinoin results in increased expression of RUNX2 mRNA21934132|2481997
D014212TretinoinTretinoin results in increased expression of RUNX2 mRNA16350840
C011559tributyltintributyltin results in decreased expression of RUNX2 mRNA23322813|2451344
C012589trichostatin Atrichostatin A results in increased expression of RUNX2 mRNA24935251
C053549triflumizoltriflumizol results in decreased expression of RUNX2 mRNA23086663
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of RUNX2 mRNA19042947
C057693troglitazonetroglitazone results in decreased expression of RUNX2 mRNA16813520|1912227
C057693troglitazonetroglitazone inhibits the reaction [BMP2 protein results in increased expression of RUNX2 mRNA]19122273
D014414TungstenTungsten results in decreased expression of RUNX2 mRNA26865663
C101044tyrphostin AG 1478tyrphostin AG 1478 results in decreased expression of RUNX2 mRNA20197312
C113580U 0126U 0126 inhibits the reaction [Ascorbic Acid results in increased expression of RUNX2 mRNA]20530736
C113580U 0126U 0126 inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]24080574
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX2 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased methylation of RUNX2 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of RUNX2 mRNA23179753|2438349
D014635Valproic AcidValproic Acid results in decreased expression of RUNX2 mRNA23042728
D014638VanadatesVanadates results in increased expression of RUNX2 mRNA22714537
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of RUNX2 gene25560391
D014801Vitamin A[Cryptoxanthins co-treated with Vitamin A] results in increased expression of RUNX2 mRNA15962303
D012256RiboflavinRiboflavin analog results in increased expression of RUNX2 protein20688149
D009536NiacinamideNiacinamide inhibits the reaction [SIRT1 protein binds to RUNX2 protein]22539994
D009536NiacinamideNiacinamide results in decreased expression of RUNX2 protein22539994
D009536NiacinamideNiacinamide results in increased acetylation of RUNX2 protein22539994
D009536Niacinamideresveratrol inhibits the reaction [Niacinamide inhibits the reaction [SIRT1 protein binds to RUNX2 protein]]22539994
D009536Niacinamideresveratrol inhibits the reaction [Niacinamide results in decreased expression of RUNX2 protein]22539994
D009536Niacinamideresveratrol inhibits the reaction [Niacinamide results in increased acetylation of RUNX2 protein]22539994
D009536NiacinamideNiacinamide results in decreased expression of RUNX2 mRNA16813520
D009536NiacinamideNiacinamide results in decreased expression of RUNX2 protein22539994
D009536Niacinamideresveratrol inhibits the reaction [Niacinamide results in decreased expression of RUNX2 protein]22539994
D009536NiacinamideNiacinamide results in increased expression of RUNX2 mRNA16813520
D009536Niacinamide[resveratrol promotes the reaction [SIRT1 protein binds to RUNX2 protein]] inhibits the reaction [Niacinamide results in increased expression of PPARG]22539994
D009536Niacinamide[resveratrol results in decreased acetylation of RUNX2 protein] inhibits the reaction [Niacinamide results in increased expression of PPARG]22539994
D002762Cholecalciferol[Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA17692823
D014812Vitamin KQuercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of RUNX2 mRNA]23117658
D014812Vitamin K[Warfarin co-treated with Vitamin K] results in increased expression of RUNX2 mRNA23117658
D010837Vitamin K 1Losartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 mRNA]27412937
D010837Vitamin K 1Losartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 protein]27412937
D010837Vitamin K 1[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 mRNA27412937
D010837Vitamin K 1[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 protein27412937
D014859WarfarinWarfarin inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein]21910061
D014859WarfarinWarfarin inhibits the reaction [RUNX2 protein results in increased expression of ALPL mRNA]21910061
D014859WarfarinWarfarin inhibits the reaction [RUNX2 protein results in increased expression of BGLAP mRNA]21910061
D014859WarfarinLosartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 mRNA]27412937
D014859WarfarinLosartan affects the reaction [[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 protein]27412937
D014859WarfarinQuercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of RUNX2 mRNA]23117658
D014859Warfarin[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 mRNA27412937
D014859Warfarin[Warfarin co-treated with Vitamin K 1] affects the expression of RUNX2 protein27412937
D014859Warfarin[Warfarin co-treated with Vitamin K] results in increased expression of RUNX2 mRNA23117658
D015032ZincZinc deficiency results in decreased expression of RUNX2 mRNA21893222
D015032ZincZinc deficiency results in decreased expression of RUNX2 protein21893222
C016837zinc chloride"[zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of RUNX2 protein"19913120
C016837zinc chloride"[zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 mRNA"19913120
C016837zinc chloride"[zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 protein"19913120
D019287Zinc SulfateCycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA]18327666
D019287Zinc SulfateDichlororibofuranosylbenzimidazole inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA]18327666
D019287Zinc SulfateZinc Sulfate results in increased expression of RUNX2 mRNA18327666
C088658zoledronic acidzoledronic acid results in increased expression of RUNX2 mRNA25596134

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding-IEA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-IBA21873635  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IEA-  
GO:0003682chromatin binding-IEA-  
GO:0003700DNA-binding transcription factor activity-NAS9182765  
GO:0005515protein binding-IPI11965546  12145306  16299379  17251981  17377532  20160071  
22065775  24113655  25331851  
GO:0005524ATP binding-IEA-  
GO:0019904protein domain specific binding-IEA-  
GO:0043425bHLH transcription factor binding-IEA-  
GO:0070491repressing transcription factor binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001503ossification-TAS12217689  
GO:0001649osteoblast differentiation-IEP20128911  
GO:0001649osteoblast differentiation-TAS12217689  
GO:0001958endochondral ossification-IEA-  
GO:0002051osteoblast fate commitment-IEA-  
GO:0002063chondrocyte development-IEA-  
GO:0002076osteoblast development-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IBA21873635  
GO:0006367transcription initiation from RNA polymerase II promoter-TAS-  
GO:0008284positive regulation of cell proliferation-IEA-  
GO:0030097hemopoiesis-IBA21873635  
GO:0030182neuron differentiation-IBA21873635  
GO:0030217T cell differentiation-IEA-  
GO:0030509BMP signaling pathway-ISS-  
GO:0032332positive regulation of chondrocyte differentiation-IEA-  
GO:0035115embryonic forelimb morphogenesis-IEA-  
GO:0040036regulation of fibroblast growth factor receptor signaling pathway-IEA-  
GO:0042475odontogenesis of dentin-containing tooth-IEA-  
GO:0042487regulation of odontogenesis of dentin-containing tooth-IEA-  
GO:0045595regulation of cell differentiation-IBA21873635  
GO:0045669positive regulation of osteoblast differentiation-IMP28703881  
GO:0045879negative regulation of smoothened signaling pathway-IEA-  
GO:0045892negative regulation of transcription, DNA-templated-IDA11965546  
GO:0045893positive regulation of transcription, DNA-templated-IDA11965546  
GO:0045944positive regulation of transcription by RNA polymerase II-IMP28505335  28703881  28738062  
GO:0048469cell maturation-IEA-  
GO:0048701embryonic cranial skeleton morphogenesis-IEA-  
GO:0048863stem cell differentiation-IEA-  
GO:0071773cellular response to BMP stimulus-ISS-  
GO:1901522positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000790nuclear chromatin-ISS-  
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA28505335  28738062  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005667transcription factor complex-IEA-  
GO:0005829cytosol-TAS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-2032785YAP1- and WWTR1 (TAZ)-stimulated gene expressionIEA
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-212436Generic Transcription PathwayIEA
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-73857RNA Polymerase II TranscriptionIEA
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-74160Gene expression (Transcription)IEA
R-HSA-8878166Transcriptional regulation by RUNX2TAS
R-HSA-8878166Transcriptional regulation by RUNX2IEA
R-HSA-8878171Transcriptional regulation by RUNX1TAS
R-HSA-8939246RUNX1 regulates transcription of genes involved in differentiation of myeloid cellsTAS
R-HSA-8939902Regulation of RUNX2 expression and activityTAS
R-HSA-8939902Regulation of RUNX2 expression and activityIEA
R-HSA-8940973RUNX2 regulates osteoblast differentiationIEA
R-HSA-8940973RUNX2 regulates osteoblast differentiationTAS
R-HSA-8941284RUNX2 regulates chondrocyte maturationIEA
R-HSA-8941326RUNX2 regulates bone developmentTAS
R-HSA-8941326RUNX2 regulates bone developmentIEA
R-HSA-8941332RUNX2 regulates genes involved in cell migrationTAS
R-HSA-8941332RUNX2 regulates genes involved in cell migrationIEA
R-HSA-8941333RUNX2 regulates genes involved in differentiation of myeloid cellsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24777817Sub-toxic nicotine concentrations affect extracellular matrix and growth factor signaling gene expressions in human osteoblasts. (2014 Dec)Marinucci LJ Cell Physiol
24205156Heterodimeric BMP-2/7 antagonizes the inhibition of all-trans retinoic acid and promotes the osteoblastogenesis. (2013)Bi WPLoS One
24570271The association between genetic variants of RUNX2, ADIPOQ and vertebral fracture in Korean postmenopausal women. (2015 Mar)Kim KCJ Bone Miner Metab
26186010Effects of Curculigoside on Memory Impairment and Bone Loss via Anti-Oxidative Character in APP/PS1 Mutated Transgenic Mice. (2015)Zhao LPLoS One
27704615Role of Runx2 polymorphisms in risk and prognosis of ossification of posterior longitudinal ligament. (2017 Jul)Chang FJ Clin Lab Anal
28314924Leptin induces osteoblast differentiation of human valvular interstitial cells via the Akt and ERK pathways. (2017 Jun)Rosa MActa Diabetol
28927744Impact of resveratrol on bone repair in rats exposed to cigarette smoke inhalation: histomorphometric and bone-related gene expression analysis. (2018 Apr)Franck FCInt J Oral Maxillofac Surg
23030247Nicotine alters MicroRNA expression and hinders human adult stem cell regenerative potential. (2013 Mar 1)Ng TKStem Cells Dev