| C025205 | 1,10-phenanthroline | "1,10-phenanthroline results in decreased activity of AKR1C3 protein" | 12604236 |
| C097240 | 15-deoxy-delta(12,14)-prostaglandin J2 | "[Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2" | 19997560 |
| C119129 | 18alpha-glycyrrhetinic acid | 18alpha-glycyrrhetinic acid affects the activity of AKR1C3 protein | 11165023 |
| C031903 | 1-UFT protocol | AKR1C3 protein results in increased susceptibility to 1-UFT protocol | 16734730 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] | 21787718 |
| C012796 | 2-butenal | 2-butenal results in increased expression of AKR1C3 mRNA | 20471460 |
| C520534 | 2'-hydroxyflavanone | 2'-hydroxyflavanone results in decreased activity of AKR1C3 protein | 19007764 |
| C018156 | 3',3'',5',5''-tetrabromophenolphthalein | "3',3'',5',5''-tetrabromophenolphthalein results in decreased activity of AKR1C3 protein" | 12604236 |
| C014464 | 3,4-dichloroaniline | "3,4-dichloroaniline results in increased expression of AKR1C3 mRNA" | 24172598 |
| C052610 | 3-hydroxypregn-4-en-20-one | AKR1C3 protein results in increased chemical synthesis of 3-hydroxypregn-4-en-20-one | 25463305 |
| C009505 | 4,4'-diaminodiphenylmethane | "4,4'-diaminodiphenylmethane results in decreased expression of AKR1C3 mRNA" | 25380136 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| C032642 | 4-aminophenylarsenoxide | 4-aminophenylarsenoxide binds to AKR1C3 protein | 26598702 |
| C032642 | 4-aminophenylarsenoxide | arsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C3 protein] | 26598702 |
| C058818 | 4-benzoylbenzoic acid | 4-benzoylbenzoic acid analog results in decreased activity of AKR1C3 protein | 19010312 |
| C027576 | 4-hydroxy-2-nonenal | 4-hydroxy-2-nonenal results in increased expression of AKR1C3 protein | 22964423 |
| C027576 | 4-hydroxy-2-nonenal | 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal] | 22964423 |
| C027576 | 4-hydroxy-2-nonenal | AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal | 22964423 |
| C027576 | 4-hydroxy-2-nonenal | AKR1C3 protein results in decreased susceptibility to 4-hydroxy-2-nonenal | 23165153 |
| C027576 | 4-hydroxy-2-nonenal | AKR1C3 protein results in increased metabolism of 4-hydroxy-2-nonenal | 23165153 |
| C038193 | 4-hydroxybenzoic acid | 4-hydroxybenzoic acid analog results in decreased activity of AKR1C3 protein | 27163852 |
| C117714 | 4-hydroxyequilenin-o-quinone | [AKR1C3 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone | 21910479 |
| C403894 | 4-oxo-2-nonenal | AKR1C3 protein results in increased metabolism of 4-oxo-2-nonenal | 28025170 |
| C403894 | 4-oxo-2-nonenal | AKR1C3 protein results in decreased susceptibility to 4-oxo-2-nonenal | 23165153 |
| C403894 | 4-oxo-2-nonenal | AKR1C3 protein results in increased reduction of 4-oxo-2-nonenal | 23165153 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| C031477 | 7-hydroxycoumarin | 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal] | 22964423 |
| C031477 | 7-hydroxycoumarin | 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to Hydrogen Peroxide] | 22964423 |
| C031477 | 7-hydroxycoumarin | 7-hydroxycoumarin results in increased expression of AKR1C3 mRNA | 28263721 |
| C031477 | 7-hydroxycoumarin | 7-hydroxycoumarin results in increased expression of AKR1C3 protein | 22964423 |
| C429845 | 7-hydroxyflavone | 7-hydroxyflavone results in decreased activity of AKR1C3 protein | 19007764 |
| C020738 | 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene | "9,10-dihydro-9,10-dihydroxybenzo(a)pyrene results in increased expression of AKR1C3 mRNA" | 26238291 |
| C005399 | 9,10-phenanthrenequinone | "9,10-phenanthrenequinone results in increased expression of AKR1C3 protein" | 29108775 |
| C005399 | 9,10-phenanthrenequinone | "AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone" | 17950253|2910877 |
| C005399 | 9,10-phenanthrenequinone | "AKR1C3 protein results in increased reduction of 9,10-phenanthrenequinone" | 19442656|2185133 |
| C005399 | 9,10-phenanthrenequinone | "[AKR1C3 protein results in increased reduction of 9,10-phenanthrenequinone] which results in increased abundance of Superoxides" | 19442656 |
| C005399 | 9,10-phenanthrenequinone | "AKR1C3 protein results in increased reduction of and affects the activity of 9,10-phenanthrenequinone" | 21910479 |
| C005399 | 9,10-phenanthrenequinone | "Indomethacin analog inhibits the reaction [AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone]" | 17950253 |
| C005399 | 9,10-phenanthrenequinone | "Indomethacin inhibits the reaction [AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone]" | 17950253 |
| C005399 | 9,10-phenanthrenequinone | "N-(4-chlorobenzoyl)melatonin inhibits the reaction [AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone]" | 17950253 |
| C031390 | 9-cis-retinal | AKR1C3 protein mutant form results in increased reduction of 9-cis-retinal | 21851338 |
| C031390 | 9-cis-retinal | AKR1C3 protein results in increased reduction of 9-cis-retinal | 21851338 |
| C037112 | 9-deoxy-delta-9-prostaglandin D2 | [AKR1C3 protein results in decreased metabolism of Prostaglandin D2] which results in decreased chemical synthesis of 9-deoxy-delta-9-prostaglandin D2 | 20036328 |
| C023723 | acenaphthene-1-ol | [AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol | 25446855 |
| C023723 | acenaphthene-1-ol | AKR1C3 protein results in increased oxidation of acenaphthene-1-ol | 23261716 |
| C023723 | acenaphthene-1-ol | dichloro(4-cymene)ruthenium(II) analog inhibits the reaction [[AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| C023723 | acenaphthene-1-ol | dichloro(4-cymene)ruthenium(II) inhibits the reaction [[AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| C023723 | acenaphthene-1-ol | Ruthenium Compounds analog inhibits the reaction [[AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of AKR1C3 mRNA | 21420995 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] | 21787718 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AKR1C3 mRNA] | 18829485 |
| D000395 | Air Pollutants, Occupational | "Air Pollutants, Occupational results in decreased expression of AKR1C3 mRNA" | 23195993 |
| C028952 | allopregnan-20 alpha-ol-3-one | AKR1C3 protein results in increased chemical synthesis of allopregnan-20 alpha-ol-3-one | 25463305 |
| C016836 | allopregnane-3,20-diol | "AKR1C3 protein results in increased chemical synthesis of allopregnane-3,20-diol" | 25463305 |
| D043582 | 5-alpha-Dihydroprogesterone | AKR1C3 protein results in increased chemical synthesis of 5-alpha-Dihydroprogesterone | 25463305 |
| D004092 | 20-alpha-Dihydroprogesterone | AKR1C3 protein results in increased chemical synthesis of 20-alpha-Dihydroprogesterone | 25463305 |
| D004092 | 20-alpha-Dihydroprogesterone | [AKR1C3 protein results in increased metabolism of Progesterone] which results in increased chemical synthesis of 20-alpha-Dihydroprogesterone | 19010312 |
| D004092 | 20-alpha-Dihydroprogesterone | [AKR1C3 protein results in increased reduction of Progesterone] which results in increased chemical synthesis of 20-alpha-Dihydroprogesterone | 20036328 |
| D013196 | Dihydrotestosterone | [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of Dihydrotestosterone | 19010312 |
| D013196 | Dihydrotestosterone | AKR1C3 protein results in increased metabolism of Dihydrotestosterone | 14672942 |
| D013196 | Dihydrotestosterone | Flufenamic Acid inhibits the reaction [AKR1C3 protein results in increased metabolism of Dihydrotestosterone] | 14672942 |
| C510582 | alpha-methylcinnamic acid | alpha-methylcinnamic acid inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] | 23933386 |
| D000735 | Androstenedione | AKR1C3 protein results in increased metabolism of Androstenedione | 19010312 |
| D000735 | Androstenedione | [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of Dihydrotestosterone | 19010312 |
| D000735 | Androstenedione | [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of Testosterone | 19010312 |
| D000735 | Androstenedione | AKR1C3 protein results in increased reduction of Androstenedione | 17950253|2003632 |
| D000735 | Androstenedione | [AKR1C3 protein results in increased reduction of Androstenedione] which results in increased chemical synthesis of Testosterone | 20036328 |
| D000735 | Androstenedione | Indomethacin analog inhibits the reaction [AKR1C3 protein results in increased reduction of Androstenedione] | 17950253 |
| D000735 | Androstenedione | Indomethacin inhibits the reaction [AKR1C3 protein results in increased reduction of Androstenedione] | 17950253 |
| D000735 | Androstenedione | N-(4-chlorobenzoyl)melatonin inhibits the reaction [AKR1C3 protein results in increased reduction of Androstenedione] | 17950253 |
| D000966 | Antimony Potassium Tartrate | Antimony Potassium Tartrate results in increased expression of AKR1C3 mRNA | 28713220 |
| D000966 | Antimony Potassium Tartrate | Antimony Potassium Tartrate results in increased expression of AKR1C3 protein | 28713220 |
| D018501 | Antirheumatic Agents | Antirheumatic Agents results in increased expression of AKR1C3 mRNA | 24449571 |
| D047310 | Apigenin | Apigenin results in decreased activity of AKR1C3 protein | 16023337 |
| C006632 | arsenic trioxide | AKR1C3 protein results in decreased susceptibility to arsenic trioxide | 20707922 |
| C006632 | arsenic trioxide | arsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C3 protein] | 26598702 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of AKR1C3 mRNA | 19128835|2146129 |
| D001241 | Aspirin | Aspirin results in decreased activity of AKR1C3 protein | 19010312 |
| D001280 | Atrazine | Atrazine results in decreased expression of AKR1C3 mRNA | 21427058 |
| C012764 | baccharin | baccharin analog results in decreased activity of AKR1C3 protein | 25555457 |
| C012764 | baccharin | baccharin results in decreased activity of AKR1C3 protein | 25555457 |
| C051597 | Bandrowski's base | Bandrowski's base results in increased expression of AKR1C3 mRNA | 20566472 |
| C030935 | benz(a)anthracene | benz(a)anthracene results in increased expression of AKR1C3 mRNA | 22236718 |
| C495787 | benz(a)anthracene-3,4-dione | "AKR1C3 protein results in increased reduction of and affects the activity of benz(a)anthracene-3,4-dione" | 21910479 |
| D001553 | Benzbromarone | Benzbromarone results in decreased activity of AKR1C3 protein | 12604236 |
| C030233 | benzo(a)pyrene-1,6-quinone | "AKR1C3 protein results in increased reduction of and affects the activity of benzo(a)pyrene-1,6-quinone" | 21910479 |
| C018003 | benzo(a)pyrene-3,6-quinone | "AKR1C3 protein results in increased reduction of and affects the activity of benzo(a)pyrene-3,6-quinone" | 21910479 |
| C018003 | benzo(a)pyrene-3,6-quinone | "[AKR1C3 protein results in increased reduction of and affects the activity of benzo(a)pyrene-3,6-quinone] which results in decreased abundance of Oxygen" | 21910479 |
| C018003 | benzo(a)pyrene-3,6-quinone | "[AKR1C3 protein results in increased reduction of and affects the activity of benzo(a)pyrene-3,6-quinone] which results in increased chemical synthesis of Hydrogen Peroxide" | 21910479 |
| C018003 | benzo(a)pyrene-3,6-quinone | "[AKR1C3 protein results in increased reduction of and affects the activity of benzo(a)pyrene-3,6-quinone] which results in increased chemical synthesis of Superoxides" | 21910479 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | "[AKR1C3 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol" | 21910479 |
| C076588 | benzo(a)pyrene-7,8-dione | "[AKR1C3 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione" | 21910479 |
| C076588 | benzo(a)pyrene-7,8-dione | "AKR1C3 protein results in increased chemical synthesis of benzo(a)pyrene-7,8-dione" | 22394341 |
| D019324 | beta-Naphthoflavone | beta-Naphthoflavone results in increased expression of AKR1C3 mRNA | 19737606 |
| D019817 | Benzoic Acid | Benzoic Acid results in increased expression of AKR1C3 mRNA | 20566472 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of AKR1C3 mRNA | 20106945|2163298 |
| D001564 | Benzo(a)pyrene | [Particulate Matter co-treated with Benzo(a)pyrene] results in increased expression of AKR1C3 mRNA | 17612574 |
| D001564 | Benzo(a)pyrene | [Vehicle Emissions co-treated with Benzo(a)pyrene] results in increased expression of AKR1C3 mRNA | 17612574 |
| D001564 | Benzo(a)pyrene | AKR1C3 protein results in increased metabolism of Benzo(a)pyrene | 22394341 |
| C072553 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [tolfenamic acid inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Cisplatin]] | 23165153 |
| C072553 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1C3 mRNA | 21215737|2316515 |
| D004958 | Estradiol | [AKR1C3 protein results in increased metabolism of Estrone] which results in increased chemical synthesis of Estradiol | 19010312 |
| D004958 | Estradiol | [AKR1C3 protein results in increased reduction of Estrone] which results in increased chemical synthesis of Estradiol | 20036328 |
| D004958 | Estradiol | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of AKR1C3 mRNA | 19619570 |
| D004958 | Estradiol | Estradiol results in decreased expression of AKR1C3 mRNA | 19619570|2301914 |
| D004958 | Estradiol | AKR1C3 protein results in increased activity of Estradiol | 19320734 |
| C095105 | bexarotene | bexarotene results in increased expression of AKR1C3 mRNA | 17178900 |
| C004541 | biochanin A | biochanin A results in decreased activity of AKR1C3 protein | 19007764 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of AKR1C3 mRNA | 25181051 |
| D000069286 | Bortezomib | Bortezomib results in increased expression of AKR1C3 mRNA | 21215737 |
| D001960 | Bromazepam | Bromazepam results in decreased activity of AKR1C3 protein | 11995921 |
| D001971 | Bromocriptine | Bromocriptine results in increased expression of AKR1C3 mRNA | 21427058 |
| D001971 | Bromocriptine | methyl cellosolve inhibits the reaction [Bromocriptine results in increased expression of AKR1C3 mRNA] | 21427058 |
| D019819 | Budesonide | AKR1C3 protein results in increased reduction of Budesonide | 21276783 |
| D002104 | Cadmium | Cadmium results in increased expression of AKR1C3 mRNA | 21120746 |
| C028031 | cadmium acetate | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] | 21787718 |
| C028031 | cadmium acetate | Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] | 21787718 |
| C028031 | cadmium acetate | cadmium acetate results in increased expression of AKR1C3 mRNA | 21787718 |
| C028031 | cadmium acetate | cadmium acetate results in increased expression of AKR1C3 protein | 21787718 |
| C028031 | cadmium acetate | Cycloheximide inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] | 21787718 |
| C055494 | caffeic acid phenethyl ester | caffeic acid phenethyl ester results in decreased activity of AKR1C3 protein | 27163852 |
| D000069287 | Capecitabine | AKR1C3 protein results in increased susceptibility to Capecitabine | 16734730 |
| D002220 | Carbamazepine | Carbamazepine affects the expression of AKR1C3 mRNA | 25979313 |
| D020245 | p-Chloromercuribenzoic Acid | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| D020245 | p-Chloromercuribenzoic Acid | p-Chloromercuribenzoic Acid results in increased expression of AKR1C3 mRNA | 26272509 |
| D002911 | Chrysenes | AKR1C3 protein results in increased reduction of and affects the activity of Chrysenes | 21910479 |
| C020722 | cinnamyl alcohol | cinnamyl alcohol results in increased expression of AKR1C3 mRNA | 20566472 |
| C005522 | cloxazolam | cloxazolam results in decreased activity of AKR1C3 protein | 11995921|1260423 |
| C018021 | cobaltous chloride | cobaltous chloride results in decreased expression of AKR1C3 mRNA | 17553155 |
| D009243 | NAD | [AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol | 25446855 |
| D009243 | NAD | dichloro(4-cymene)ruthenium(II) analog inhibits the reaction [[AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D009243 | NAD | dichloro(4-cymene)ruthenium(II) inhibits the reaction [[AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D009243 | NAD | Ruthenium Compounds analog inhibits the reaction [[AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D009249 | NADP | "[AKR1C3 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol" | 21910479 |
| D009249 | NADP | [AKR1C3 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone | 21910479 |
| D009249 | NADP | "[AKR1C3 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione" | 21910479 |
| D009249 | NADP | [AKR1C3 protein co-treated with NADP] results in increased reduction of cyclopentanone | 23261716 |
| D009249 | NADP | Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein co-treated with NADP] results in increased reduction of cyclopentanone] | 23261716 |
| D009249 | NADP | NADP inhibits the reaction [AKR1C3 protein results in increased oxidation of Hydroxysteroids] | 14672942 |
| D009249 | NADP | NADP promotes the reaction [AKR1C3 protein results in increased reduction of cyclopentanone] | 23261716 |
| D005576 | Colforsin | Colforsin results in decreased expression of AKR1C3 mRNA | 28235592 |
| C075384 | coniferaldehyde | coniferaldehyde results in increased expression of AKR1C3 mRNA | 26275128 |
| D003300 | Copper | [NSC 689534 binds to Copper] which results in increased expression of AKR1C3 mRNA | 20971185 |
| D019327 | Copper Sulfate | Copper Sulfate results in increased expression of AKR1C3 mRNA | 19549813 |
| D003375 | Coumestrol | Coumestrol results in decreased activity of AKR1C3 protein | 19007764 |
| C010092 | cresolphthalein | cresolphthalein results in decreased activity of AKR1C3 protein | 12604236 |
| D003513 | Cycloheximide | Cycloheximide inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] | 21787718 |
| C016327 | cyclopentanol | AKR1C3 protein results in increased oxidation of cyclopentanol | 23261716 |
| C007201 | cyclopentanone | [AKR1C3 protein co-treated with NADP] results in increased reduction of cyclopentanone | 23261716 |
| C007201 | cyclopentanone | AKR1C3 protein results in increased reduction of cyclopentanone | 23261716 |
| C007201 | cyclopentanone | Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein co-treated with NADP] results in increased reduction of cyclopentanone] | 23261716 |
| C007201 | cyclopentanone | NADP promotes the reaction [AKR1C3 protein results in increased reduction of cyclopentanone] | 23261716 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of AKR1C3 mRNA | 25562108 |
| D000069439 | Dasatinib | Dasatinib results in increased expression of AKR1C3 mRNA | 20579391 |
| D003630 | Daunorubicin | AKR1C3 results in increased metabolism of Daunorubicin | 20837989 |
| D015230 | Prostaglandin D2 | AKR1C3 protein results in decreased metabolism of Prostaglandin D2 | 20036328 |
| D015230 | Prostaglandin D2 | [AKR1C3 protein results in decreased metabolism of Prostaglandin D2] which results in decreased chemical synthesis of 9-deoxy-delta-9-prostaglandin D2 | 20036328 |
| D015230 | Prostaglandin D2 | AKR1C3 protein results in decreased susceptibility to Prostaglandin D2 | 20036328 |
| D015230 | Prostaglandin D2 | AKR1C3 protein results in increased metabolism of Prostaglandin D2 | 19010312 |
| D015230 | Prostaglandin D2 | AKR1C3 protein results in increased reduction of Prostaglandin D2 | 20036328 |
| D015230 | Prostaglandin D2 | [AKR1C3 protein results in increased reduction of Prostaglandin D2] which results in increased chemical synthesis of Dinoprost | 20036328 |
| D015230 | Prostaglandin D2 | Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost] | 19997560 |
| D015230 | Prostaglandin D2 | "[Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2" | 19997560 |
| D015230 | Prostaglandin D2 | AKR1C3 protein results in increased metabolism of Prostaglandin D2 | 19997560 |
| D015230 | Prostaglandin D2 | [AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost | 19997560 |
| D017135 | Desogestrel | Desogestrel results in decreased activity of AKR1C3 protein | 21182831 |
| D003907 | Dexamethasone | Dexamethasone results in increased expression of AKR1C3 mRNA | 25047013 |
| D003907 | Dexamethasone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AKR1C3 mRNA | 28628672 |
| D003975 | Diazepam | Diazepam results in decreased activity of AKR1C3 protein | 11995921|1260423 |
| C041517 | dibenzo(a,l)pyrene | "[Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C3 mRNA" | 17612574 |
| C041517 | dibenzo(a,l)pyrene | "[Vehicle Emissions co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C3 mRNA" | 17612574 |
| C530610 | dichloro(4-cymene)ruthenium(II) | dichloro(4-cymene)ruthenium(II) analog inhibits the reaction [[AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| C530610 | dichloro(4-cymene)ruthenium(II) | dichloro(4-cymene)ruthenium(II) inhibits the reaction [[AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D002945 | Cisplatin | AKR1C3 protein results in decreased susceptibility to Cisplatin | 23165153 |
| D002945 | Cisplatin | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [tolfenamic acid inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Cisplatin]] | 23165153 |
| D002945 | Cisplatin | [Cisplatin co-treated with jinfukang] results in increased expression of AKR1C3 mRNA | 27392435 |
| D002945 | Cisplatin | Cisplatin results in increased expression of AKR1C3 mRNA | 23165153|2739243 |
| D002945 | Cisplatin | Cisplatin results in increased expression of AKR1C3 protein | 23165153 |
| D002945 | Cisplatin | [Cisplatin results in increased expression of AKR1C3] which results in decreased susceptibility to Cisplatin | 23165153 |
| D002945 | Cisplatin | tolfenamic acid inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Cisplatin] | 23165153 |
| C000944 | dicrotophos | dicrotophos results in decreased expression of AKR1C3 mRNA | 28302478 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in increased expression of AKR1C3 mRNA | 19665456 |
| D004054 | Diethylstilbestrol | sodium arsenite promotes the reaction [Diethylstilbestrol results in increased expression of AKR1C3 mRNA] | 19665456 |
| D004101 | Dihydroxydihydrobenzopyrenes | AKR1C3 protein results in increased reduction of and affects the activity of Dihydroxydihydrobenzopyrenes | 21910479 |
| D004137 | Dinitrochlorobenzene | Dinitrochlorobenzene results in increased expression of AKR1C3 mRNA | 20566472 |
| D004221 | Disulfiram | Disulfiram results in increased expression of AKR1C3 mRNA | 20566472 |
| D004237 | Diuron | Diuron metabolite results in increased expression of AKR1C3 mRNA | 24172598 |
| C025034 | doxifluridine | AKR1C3 protein results in increased susceptibility to doxifluridine | 16734730 |
| D004317 | Doxorubicin | AKR1C3 protein affects the reduction of Doxorubicin | 18635746 |
| D004317 | Doxorubicin | AKR1C3 results in increased metabolism of Doxorubicin | 20837989 |
| D000068538 | Dutasteride | Dutasteride results in increased expression of AKR1C3 mRNA | 16806904 |
| D004394 | Dydrogesterone | Dydrogesterone results in decreased activity of AKR1C3 protein | 21182831 |
| D004394 | Dydrogesterone | Dydrogesterone results in decreased expression of AKR1C3 mRNA | 23183084 |
| C045651 | epigallocatechin gallate | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AKR1C3 mRNA | 22079256 |
| D004949 | Estazolam | Estazolam results in decreased activity of AKR1C3 protein | 11995921 |
| D004970 | Estrone | AKR1C3 protein results in increased metabolism of Estrone | 19010312 |
| D004970 | Estrone | [AKR1C3 protein results in increased metabolism of Estrone] which results in increased chemical synthesis of Estradiol | 19010312 |
| D004970 | Estrone | AKR1C3 protein results in increased reduction of Estrone | 20036328 |
| D004970 | Estrone | [AKR1C3 protein results in increased reduction of Estrone] which results in increased chemical synthesis of Estradiol | 20036328 |
| D005054 | Eugenol | Eugenol results in increased expression of AKR1C3 mRNA | 20566472 |
| D015025 | Zearalenone | Zearalenone results in decreased activity of AKR1C3 protein | 16023337 |
| C084519 | farnesal | AKR1C3 protein results in increased reduction of farnesal | 21187079 |
| C007702 | farnesoic acid | [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis of farnesoic acid | 21187079 |
| C007702 | farnesoic acid | [tolfenamic acid results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis of farnesoic acid | 21187079 |
| D005204 | Farnesol | AKR1C3 protein results in increased chemical synthesis of Farnesol | 21187079 |
| D005204 | Farnesol | [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol | 21187079 |
| D005204 | Farnesol | [tolfenamic acid results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol | 21187079 |
| C001209 | fenamic acid | fenamic acid analog results in decreased activity of AKR1C3 protein | 19010312 |
| C006012 | fenofibric acid | AKR1C3 protein results in increased reduction of fenofibric acid | 27599626 |
| D005439 | Flufenamic Acid | Flufenamic Acid binds to AKR1C3 protein | 14996743 |
| D005439 | Flufenamic Acid | Flufenamic Acid inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] | 23933386 |
| D005439 | Flufenamic Acid | Flufenamic Acid inhibits the reaction [AKR1C3 protein results in increased metabolism of Dihydrotestosterone] | 14672942 |
| D005439 | Flufenamic Acid | Flufenamic Acid results in decreased activity of AKR1C3 protein | 12604236 |
| D005439 | Flufenamic Acid | Flufenamic Acid results in decreased activity of AKR1C3 protein | 19007764|1944265 |
| C007734 | flunisolide | AKR1C3 protein results in increased reduction of flunisolide | 21276783 |
| D005445 | Flunitrazepam | Flunitrazepam results in decreased activity of AKR1C3 protein | 11995921 |
| D005472 | Fluorouracil | AKR1C3 protein affects the susceptibility to Fluorouracil | 16217747 |
| D005472 | Fluorouracil | Fluorouracil affects the expression of AKR1C3 mRNA | 16584549 |
| D005480 | Flurbiprofen | Flurbiprofen results in decreased activity of AKR1C3 protein | 19010312|2118707 |
| D005480 | Flurbiprofen | [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis of farnesoic acid | 21187079 |
| D005480 | Flurbiprofen | [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol | 21187079 |
| D005557 | Formaldehyde | Formaldehyde results in decreased expression of AKR1C3 mRNA | 23649840 |
| D005557 | Formaldehyde | Formaldehyde results in increased expression of AKR1C3 mRNA | 28937961 |
| C017338 | geranylgeraniol | AKR1C3 protein results in increased chemical synthesis of geranylgeraniol | 21187079 |
| D005907 | Gliclazide | Gliclazide results in decreased activity of AKR1C3 protein | 26362498 |
| C057619 | glimepiride | glimepiride results in decreased activity of AKR1C3 protein | 26362498 |
| D005913 | Glipizide | Glipizide results in decreased activity of AKR1C3 protein | 26362498 |
| C010969 | gliquidone | gliquidone results in decreased activity of AKR1C3 protein | 26362498 |
| D005905 | Glyburide | Glyburide results in decreased activity of AKR1C3 protein | 26362498 |
| C071834 | glycidamide | glycidamide results in increased expression of AKR1C3 mRNA | 17822822 |
| D006034 | Glycyrrhetinic Acid | Glycyrrhetinic Acid results in decreased activity of AKR1C3 protein | 12604236 |
| D006589 | Hexestrol | Hexestrol results in decreased activity of AKR1C3 protein | 12604236 |
| C080043 | hexyl cinnamic aldehyde | hexyl cinnamic aldehyde results in increased expression of AKR1C3 mRNA | 20566472 |
| D017313 | Fenretinide | Fenretinide results in decreased expression of AKR1C3 mRNA | 28973697 |
| D006854 | Hydrocortisone | AKR1C3 protein results in increased reduction of Hydrocortisone | 21276783 |
| D006861 | Hydrogen Peroxide | 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to Hydrogen Peroxide] | 22964423 |
| D006861 | Hydrogen Peroxide | AKR1C3 mutant form results in increased susceptibility to Hydrogen Peroxide | 22964423 |
| D006861 | Hydrogen Peroxide | "[AKR1C3 protein results in increased reduction of and affects the activity of benzo(a)pyrene-3,6-quinone] which results in increased chemical synthesis of Hydrogen Peroxide" | 21910479 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased expression of AKR1C3 protein | 22964423 |
| D006914 | Hydroxysteroids | AKR1C3 protein results in increased abundance of Hydroxysteroids | 14672942 |
| D006914 | Hydroxysteroids | AKR1C3 protein results in increased oxidation of Hydroxysteroids | 14672942 |
| D006914 | Hydroxysteroids | NADP inhibits the reaction [AKR1C3 protein results in increased oxidation of Hydroxysteroids] | 14672942 |
| D007052 | Ibuprofen | Ibuprofen results in decreased activity of AKR1C3 protein | 19010312 |
| C492448 | ICG 001 | ICG 001 results in decreased expression of AKR1C3 mRNA | 26191083 |
| D007213 | Indomethacin | "Indomethacin analog inhibits the reaction [AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone]" | 17950253 |
| D007213 | Indomethacin | Indomethacin analog inhibits the reaction [AKR1C3 protein results in increased reduction of Androstenedione] | 17950253 |
| D007213 | Indomethacin | Indomethacin analog results in decreased activity of AKR1C3 protein | 17950253|1901031 |
| D007213 | Indomethacin | Indomethacin binds to AKR1C3 protein | 14996743 |
| D007213 | Indomethacin | "Indomethacin inhibits the reaction [AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone]" | 17950253 |
| D007213 | Indomethacin | Indomethacin inhibits the reaction [AKR1C3 protein results in increased reduction of Androstenedione] | 17950253 |
| D007213 | Indomethacin | Indomethacin results in decreased activity of AKR1C3 protein | 12604236|1795025 |
| D007213 | Indomethacin | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AKR1C3 mRNA | 28628672 |
| D007213 | Indomethacin | Indomethacin results in decreased activity of AKR1C3 protein | 19007764|1944265 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AKR1C3 mRNA | 28628672 |
| C036643 | isoeugenol | isoeugenol results in increased expression of AKR1C3 mRNA | 20566472 |
| C544151 | jinfukang | [Cisplatin co-treated with jinfukang] results in increased expression of AKR1C3 mRNA | 27392435 |
| C544151 | jinfukang | jinfukang results in increased expression of AKR1C3 mRNA | 27392435 |
| D019344 | Lactic Acid | Lactic Acid results in increased expression of AKR1C3 mRNA | 20566472 |
| D008095 | Lithocholic Acid | Lithocholic Acid results in decreased activity of AKR1C3 protein | 12604236|2185133 |
| D008469 | Meclofenamic Acid | Meclofenamic Acid results in decreased activity of AKR1C3 protein | 19010312|2636249 |
| D008472 | Medazepam | Medazepam results in decreased activity of AKR1C3 protein | 11995921|1260423 |
| D017258 | Medroxyprogesterone Acetate | Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein co-treated with NADP] results in increased reduction of cyclopentanone] | 23261716 |
| D017258 | Medroxyprogesterone Acetate | Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost] | 19997560 |
| D017258 | Medroxyprogesterone Acetate | "[Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2" | 19997560 |
| D017258 | Medroxyprogesterone Acetate | Medroxyprogesterone Acetate results in decreased activity of AKR1C3 protein | 12604236|1999756 |
| D008528 | Mefenamic Acid | Mefenamic Acid analog results in decreased activity of AKR1C3 protein | 19010312 |
| C042720 | mercuric bromide | mercuric bromide results in increased expression of AKR1C3 mRNA | 26272509 |
| C042720 | mercuric bromide | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| C005219 | methyl cellosolve | methyl cellosolve inhibits the reaction [Bromocriptine results in increased expression of AKR1C3 mRNA] | 21427058 |
| C005219 | methyl cellosolve | methyl cellosolve results in decreased expression of AKR1C3 mRNA | 21427058 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of AKR1C3 mRNA | 28001369 |
| C033069 | methyl salicylate | methyl salicylate results in increased expression of AKR1C3 mRNA | 20566472 |
| C526888 | N-(4-chlorobenzoyl)melatonin | "N-(4-chlorobenzoyl)melatonin inhibits the reaction [AKR1C3 protein results in increased metabolism of 9,10-phenanthrenequinone]" | 17950253 |
| C526888 | N-(4-chlorobenzoyl)melatonin | N-(4-chlorobenzoyl)melatonin inhibits the reaction [AKR1C3 protein results in increased reduction of Androstenedione] | 17950253 |
| C526888 | N-(4-chlorobenzoyl)melatonin | N-(4-chlorobenzoyl)melatonin results in decreased activity of AKR1C3 protein | 17950253|1901031 |
| D009281 | Naphthalenes | AKR1C3 protein results in increased reduction of and affects the activity of Naphthalenes | 21910479 |
| D015058 | 1-Naphthylisothiocyanate | 1-Naphthylisothiocyanate results in decreased expression of AKR1C3 mRNA | 25380136 |
| D009288 | Naproxen | Naproxen results in decreased activity of AKR1C3 protein | 19010312 |
| C005273 | naringenin | naringenin results in decreased activity of AKR1C3 protein | 19007764 |
| C026385 | n-hexane | n-hexane results in increased expression of AKR1C3 mRNA | 20566472 |
| D009532 | Nickel | Nickel results in decreased expression of AKR1C3 mRNA | 23195993 |
| C029938 | nickel sulfate | nickel sulfate results in increased expression of AKR1C3 mRNA | 20566472 |
| D009567 | Nitrazepam | Nitrazepam results in decreased activity of AKR1C3 protein | 11995921 |
| D009640 | Norethindrone | Norethindrone results in decreased activity of AKR1C3 protein | 21182831 |
| D016912 | Levonorgestrel | Levonorgestrel results in decreased activity of AKR1C3 protein | 21182831 |
| C558013 | NSC 689534 | [NSC 689534 binds to Copper] which results in increased expression of AKR1C3 mRNA | 20971185 |
| C025589 | ochratoxin A | ochratoxin A results in decreased expression of AKR1C3 mRNA | 19287073 |
| C016627 | octyl gallate | octyl gallate results in decreased activity of AKR1C3 protein | 27163852 |
| C103439 | oracine | AKR1C3 protein results in increased reduction of oracine | 19007764 |
| C103439 | oracine | oracine binds to AKR1C3 protein | 25595226 |
| C030110 | oxaliplatin | AKR1C3 protein affects the susceptibility to oxaliplatin | 23933386 |
| C030110 | oxaliplatin | alpha-methylcinnamic acid inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] | 23933386 |
| C030110 | oxaliplatin | Flufenamic Acid inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] | 23933386 |
| C030110 | oxaliplatin | Phenolphthalein inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] | 23933386 |
| C036006 | oxcarbazepine | AKR1C3 protein results in increased reduction of oxcarbazepine | 25063510 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of AKR1C3 mRNA | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of AKR1C3 mRNA] | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of AKR1C3 mRNA] | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | Particulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of AKR1C3 mRNA] | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | Vehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of AKR1C3 mRNA] | 17655762 |
| D010098 | Oxycodone | Oxycodone results in decreased expression of AKR1C3 mRNA | 23439660 |
| D010100 | Oxygen | "[AKR1C3 protein results in increased reduction of and affects the activity of benzo(a)pyrene-3,6-quinone] which results in decreased abundance of Oxygen" | 21910479 |
| D052638 | Particulate Matter | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of AKR1C3 mRNA] | 17655762 |
| D052638 | Particulate Matter | Particulate Matter affects the expression of AKR1C3 mRNA | 17655762 |
| D052638 | Particulate Matter | [Particulate Matter co-treated with Benzo(a)pyrene] results in increased expression of AKR1C3 mRNA | 17612574 |
| D052638 | Particulate Matter | "[Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C3 mRNA" | 17612574 |
| D052638 | Particulate Matter | Particulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of AKR1C3 mRNA] | 17655762 |
| D052638 | Particulate Matter | Particulate Matter results in increased expression of AKR1C3 mRNA | 23085030 |
| C076994 | perfluorooctane sulfonic acid | perfluorooctane sulfonic acid affects the expression of AKR1C3 mRNA | 19429403 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid affects the expression of AKR1C3 mRNA | 19429403 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in increased expression of AKR1C3 mRNA | 17681415 |
| D020113 | Phenolphthalein | Phenolphthalein inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] | 23933386 |
| D020113 | Phenolphthalein | Phenolphthalein results in decreased activity of AKR1C3 protein | 12604236 |
| D010662 | Phenylmercuric Acetate | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| D010662 | Phenylmercuric Acetate | Phenylmercuric Acetate results in increased expression of AKR1C3 mRNA | 26272509 |
| D011078 | Polychlorinated Biphenyls | Polychlorinated Biphenyls affects the expression of AKR1C3 mRNA | 21334430 |
| C027373 | potassium chromate(VI) | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AKR1C3 mRNA | 22079256 |
| C027373 | potassium chromate(VI) | potassium chromate(VI) results in decreased expression of AKR1C3 mRNA | 22079256 |
| D017035 | Pravastatin | Pravastatin results in decreased expression of AKR1C3 mRNA | 27225895 |
| D011278 | Pregnanes | AKR1C3 protein affects the metabolism of Pregnanes metabolite | 12604236 |
| D011280 | Pregnanolone | AKR1C3 protein results in increased chemical synthesis of Pregnanolone | 25463305 |
| D011374 | Progesterone | AKR1C3 protein results in increased metabolism of Progesterone | 19010312 |
| D011374 | Progesterone | [AKR1C3 protein results in increased metabolism of Progesterone] which results in increased chemical synthesis of 20-alpha-Dihydroprogesterone | 19010312 |
| D011374 | Progesterone | AKR1C3 protein results in increased reduction of Progesterone | 20036328|2546330 |
| D011374 | Progesterone | [AKR1C3 protein results in increased reduction of Progesterone] which results in increased chemical synthesis of 20-alpha-Dihydroprogesterone | 20036328 |
| D011374 | Progesterone | Progesterone results in decreased expression of AKR1C3 mRNA | 23183084 |
| D011374 | Progesterone | Progesterone results in increased expression of AKR1C3 mRNA | 23183084 |
| D019840 | 2-Propanol | 2-Propanol results in increased expression of AKR1C3 mRNA | 20566472 |
| D015237 | Dinoprost | Dinoprost results in increased expression of AKR1C3 mRNA | 20484870 |
| D015237 | Dinoprost | [AKR1C3 protein results in increased reduction of Prostaglandin D2] which results in increased chemical synthesis of Dinoprost | 20036328 |
| D015237 | Dinoprost | Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost] | 19997560 |
| D015237 | Dinoprost | "[Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12,14)-prostaglandin J2" | 19997560 |
| D015237 | Dinoprost | [AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost | 19997560 |
| D011765 | Pyruvaldehyde | Pyruvaldehyde results in increased expression of AKR1C3 mRNA | 25451587 |
| D011794 | Quercetin | Quercetin results in decreased activity of AKR1C3 protein | 19007764 |
| D011794 | Quercetin | Quercetin results in decreased activity of AKR1C3 protein | 16023337 |
| C059514 | resveratrol | [resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA | 25905778 |
| D012172 | Retinaldehyde | AKR1C3 protein results in increased reduction of Retinaldehyde | 23261716 |
| D017975 | Ruthenium Compounds | Ruthenium Compounds analog inhibits the reaction [[AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| C079198 | S 1 (combination) | AKR1C3 protein results in increased susceptibility to S 1 (combination) | 16734730 |
| D020156 | Salicylic Acid | Salicylic Acid results in decreased activity of AKR1C3 protein | 19010312 |
| C078903 | seocalcitol | seocalcitol results in increased expression of AKR1C3 mRNA | 12040012 |
| D012822 | Silicon Dioxide | Silicon Dioxide analog results in decreased expression of AKR1C3 mRNA | 25895662 |
| D012822 | Silicon Dioxide | Silicon Dioxide analog results in increased secretion of AKR1C3 protein | 25895662 |
| D012822 | Silicon Dioxide | Silicon Dioxide results in increased expression of AKR1C3 mRNA | 25351596 |
| C440975 | silybin | silybin results in decreased activity of AKR1C3 protein | 19007764 |
| D019821 | Simvastatin | Simvastatin results in decreased expression of AKR1C3 mRNA | 18192897 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of AKR1C3 mRNA | 12727804|1969616 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of AKR1C3 protein | 28713220 |
| C017947 | sodium arsenite | sodium arsenite promotes the reaction [Diethylstilbestrol results in increased expression of AKR1C3 mRNA] | 19665456 |
| C016104 | sodium bichromate | sodium bichromate results in decreased expression of AKR1C3 mRNA | 25993096 |
| D012967 | Sodium Dodecyl Sulfate | Sodium Dodecyl Sulfate results in increased expression of AKR1C3 mRNA | 20566472 |
| C075117 | squalestatin 1 | squalestatin 1 results in increased expression of AKR1C3 mRNA | 27225895 |
| D013311 | Streptozocin | [resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA | 25905778 |
| C016766 | sulforafan | sulforafan results in increased expression of AKR1C3 mRNA | 24383545 |
| D013467 | Sulindac | Sulindac results in decreased activity of AKR1C3 protein | 19010312 |
| D013469 | Sulpiride | Sulpiride results in decreased expression of AKR1C3 mRNA | 21427058 |
| D013481 | Superoxides | "[AKR1C3 protein results in increased reduction of 9,10-phenanthrenequinone] which results in increased abundance of Superoxides" | 19442656 |
| D013481 | Superoxides | "[AKR1C3 protein results in increased reduction of and affects the activity of benzo(a)pyrene-3,6-quinone] which results in increased chemical synthesis of Superoxides" | 21910479 |
| D014284 | Triiodothyronine | Triiodothyronine results in increased expression of AKR1C3 mRNA | 15507505 |
| D013739 | Testosterone | AKR1C3 promoter SNP results in increased abundance of Testosterone | 16263811 |
| D013739 | Testosterone | [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of Testosterone | 19010312 |
| D013739 | Testosterone | [AKR1C3 protein results in increased reduction of Androstenedione] which results in increased chemical synthesis of Testosterone | 20036328 |
| D013739 | Testosterone | AKR1C3 protein results in increased activity of Testosterone | 19320734 |
| C004648 | testosterone enanthate | testosterone enanthate affects the expression of AKR1C3 mRNA | 17440010 |
| D013749 | Tetrachlorodibenzodioxin | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of AKR1C3 mRNA | 19619570 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of AKR1C3 mRNA | 19619570 |
| D013749 | Tetrachlorodibenzodioxin | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of AKR1C3 mRNA] | 21215274 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of AKR1C3 mRNA | 21215274 |
| C019106 | tetralol | AKR1C3 protein affects the oxidation of tetralol | 12604236 |
| C019106 | tetralol | AKR1C3 protein results in increased metabolism of tetralol | 23165153 |
| D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in increased expression of AKR1C3 mRNA | 27404394|2786577 |
| C066340 | tolcapone | tolcapone results in decreased expression of AKR1C3 mRNA | 24136188 |
| C009500 | tolfenamic acid | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [tolfenamic acid inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Cisplatin]] | 23165153 |
| C009500 | tolfenamic acid | tolfenamic acid inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Cisplatin] | 23165153 |
| C009500 | tolfenamic acid | tolfenamic acid results in decreased activity of AKR1C3 protein | 21187079|2316515 |
| C009500 | tolfenamic acid | [tolfenamic acid results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis of farnesoic acid | 21187079 |
| C009500 | tolfenamic acid | [tolfenamic acid results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol | 21187079 |
| D014212 | Tretinoin | Tretinoin results in increased expression of AKR1C3 mRNA | 23724009 |
| C012589 | trichostatin A | trichostatin A results in increased expression of AKR1C3 mRNA | 24935251|2670570 |
| C016805 | tris(1,3-dichloro-2-propyl)phosphate | "tris(1,3-dichloro-2-propyl)phosphate results in increased expression of AKR1C3 mRNA" | 26179874 |
| C057693 | troglitazone | troglitazone results in increased expression of AKR1C3 mRNA | 28973697 |
| D014501 | Uranium | Uranium affects the expression of AKR1C3 mRNA | 15672453 |
| C005460 | uranyl acetate | uranyl acetate affects the expression of AKR1C3 mRNA | 15672453 |
| D014520 | Urethane | Urethane results in decreased expression of AKR1C3 mRNA | 28818685 |
| D014580 | Ursodeoxycholic Acid | Ursodeoxycholic Acid results in decreased activity of AKR1C3 protein | 12604236 |
| D014635 | Valproic Acid | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA" | 27188386 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of AKR1C3 mRNA | 25979313 |
| D014635 | Valproic Acid | Valproic Acid results in decreased methylation of AKR1C3 gene | 29154799 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of AKR1C3 mRNA | 23179753|2438349 |
| D001335 | Vehicle Emissions | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of AKR1C3 mRNA] | 17655762 |
| D001335 | Vehicle Emissions | Vehicle Emissions affects the expression of AKR1C3 mRNA | 17655762 |
| D001335 | Vehicle Emissions | [Vehicle Emissions co-treated with Benzo(a)pyrene] results in increased expression of AKR1C3 mRNA | 17612574 |
| D001335 | Vehicle Emissions | "[Vehicle Emissions co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C3 mRNA" | 17612574 |
| D001335 | Vehicle Emissions | Vehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of AKR1C3 mRNA] | 17655762 |
| C111237 | vorinostat | vorinostat results in decreased expression of AKR1C3 mRNA | 18769122 |
| C111237 | vorinostat | vorinostat results in increased expression of AKR1C3 mRNA | 18769122 |
| D015032 | Zinc | Zinc deficiency results in decreased expression of AKR1C3 mRNA | 22171008 |
| C020549 | zomepirac | zomepirac results in decreased activity of AKR1C3 protein | 19010312 |