Gene: ABCC3

8714
ABC31|EST90757|MLP2|MOAT-D|MRP3|cMOAT2
ATP binding cassette subfamily C member 3
protein-coding
17q21.33
Ensembl:ENSG00000108846 MIM:604323 Vega:OTTHUMG00000162245 UniprotKB:O15438
NC_000017.11
PubMed
ND|AD
3   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.260e-1 (AD)  2.655e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KCNK60.59
DCSTAMP0.588
ITGA110.582
NLRC40.579
ATG16L20.572
VDR0.569
C5AR20.569
ARID3A0.565
KDELR30.562
LSP10.556

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LHFPL1-0.381
LYPD6-0.347
DIO2-0.342
ACBD7-0.331
RXRG-0.327
NPFFR1-0.321
FGFBP3-0.315
MMD2-0.314
MRO-0.295
FBXL22-0.285

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00091CyclosporineSmall Molecule59865-13-3Approved|InvestigationalTransporter
DB00143GlutathioneSmall Molecule70-18-8Approved|Investigational|NutraceuticalTransporter
DB00158Folic AcidSmall Molecule59-30-3Approved|NutraceuticalTransporter
DB00257ClotrimazoleSmall Molecule23593-75-1ApprovedTransporter
DB00286Conjugated estrogensSmall Molecule12126-59-9ApprovedTransporter
DB00328IndomethacinSmall Molecule53-86-1Approved|InvestigationalTransporter
DB00338OmeprazoleSmall Molecule73590-58-6Approved|InvestigationalTransporter
DB00515CisplatinSmall Molecule15663-27-1ApprovedTransporter
DB00541VincristineSmall Molecule57-22-7Approved|InvestigationalTransporter
DB00544FluorouracilSmall Molecule51-21-8ApprovedTransporter
DB00563MethotrexateSmall Molecule59-05-2ApprovedTransporter
DB00661VerapamilSmall Molecule52-53-9ApprovedTransporter
DB00709LamivudineSmall Molecule134678-17-4Approved|InvestigationalTransporter
DB00773EtoposideSmall Molecule33419-42-0ApprovedTransporter
DB00973EzetimibeSmall Molecule163222-33-1ApprovedTransporter
DB00997DoxorubicinSmall Molecule23214-92-8Approved|InvestigationalTransporter
DB01011MetyraponeSmall Molecule54-36-4Approved|InvestigationalTransporter
DB01016GlyburideSmall Molecule10238-21-8ApprovedTransporter
DB01032ProbenecidSmall Molecule57-66-9Approved|InvestigationalTransporter
DB01045RifampicinSmall Molecule13292-46-1ApprovedTransporter
DB01115NifedipineSmall Molecule21829-25-4ApprovedTransporter
DB01138SulfinpyrazoneSmall Molecule57-96-5ApprovedTransporter
DB01174PhenobarbitalSmall Molecule50-06-6Approved|InvestigationalTransporter
DB02659Cholic AcidSmall Molecule81-25-4ApprovedTransporter
DB04348Taurocholic AcidSmall Molecule81-24-3ExperimentalTransporter
DB08884Gadoxetic acidSmall Molecule135326-11-3ApprovedTransporter
ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in decreased expression of ABCC3 mRNA"26377693
C4728291-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole"1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased expression of ABCC3 mRNA"27071940
C4728291-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole"NFE2L2 gene mutant form inhibits the reaction [1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole results in increased expression of ABCC3 mRNA]"27071940
C5768821-(2-trifluoromethoxyphenyl)-2-nitroethanone1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in increased expression of ABCC3 mRNA25596134
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Tetrachlorodibenzodioxin] results in increased expression of ABCC3 mRNA"17627975
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I3 protein] which results in increased expression of ABCC3 mRNA"15833929|2249639
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ABCC3 mRNA"15833929|1598641
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ABCC3 protein"15986414|2781899
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[Lithocholic Acid co-treated with 1,4-bis(2-(3,5-dichloropyridyloxy))benzene] results in increased expression of ABCC3 mRNA"18032408
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ABCC3 mRNA]"22496397
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"NR1I3 protein promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ABCC3 mRNA]"19850644|2269881
C09724015-deoxy-delta(12,14)-prostaglandin J2"ABCC3 protein affects the export of 15-deoxy-delta(12,14)-prostaglandin J2 analog"14979731
C11912918alpha-glycyrrhetinic acid18alpha-glycyrrhetinic acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA]28549656
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,5,2',5'-tetrachlorobiphenyl co-treated with 2,2',3,5',6-pentachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3,3',4',6-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of ABCC3 mRNA"29142165
C0329042,2',3,5',6-pentachlorobiphenyl"[2,5,2',5'-tetrachlorobiphenyl co-treated with 2,2',3,5',6-pentachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3,3',4',6-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of ABCC3 mRNA"29142165
C5003362,2',4,4',5-pentachlorobiphenyl"2,2',4,4',5-pentachlorobiphenyl results in increased expression of ABCC3 mRNA"11752103
C0291412,2,5,7,8-pentamethyl-1-hydroxychroman"2,2,5,7,8-pentamethyl-1-hydroxychroman results in increased expression of ABCC3 mRNA"21920950
C0329032,3,3',4',6-pentachlorobiphenyl"[2,5,2',5'-tetrachlorobiphenyl co-treated with 2,2',3,5',6-pentachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3,3',4',6-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of ABCC3 mRNA"29142165
C0700552,3',4,4',5-pentachlorobiphenyl"[2,5,2',5'-tetrachlorobiphenyl co-treated with 2,2',3,5',6-pentachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3,3',4',6-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of ABCC3 mRNA"29142165
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran affects the expression of ABCC3 mRNA"18343893|2070259
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in increased expression of ABCC3 mRNA"25768209
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of ABCC3 mRNA"20005886
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of ABCC3 mRNA"28433925
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of ABCC3 mRNA"20959002
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,5,2',5'-tetrachlorobiphenyl co-treated with 2,2',3,5',6-pentachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3,3',4',6-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of ABCC3 mRNA"29142165
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,5,2',5'-tetrachlorobiphenyl co-treated with 2,2',3,5',6-pentachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3,3',4',6-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of ABCC3 mRNA"29142165
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of ABCC3 mRNA"21346803
C08133124-norursodeoxycholic acid24-norursodeoxycholic acid results in increased expression of ABCC3 protein16472600
C0094072,5,2',5'-tetrachlorobiphenyl"[2,5,2',5'-tetrachlorobiphenyl co-treated with 2,2',3,5',6-pentachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3,3',4',6-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of ABCC3 mRNA"29142165
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of ABCC3 mRNA"21346803
C0352082-amino-4,6-dinitrotoluene"2-amino-4,6-dinitrotoluene affects the expression of ABCC3 mRNA"21346803
C0194992-nitrofluorene2-nitrofluorene results in increased expression of ABCC3 mRNA23052194
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC3 mRNA"15833929
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC3 mRNA"15833929|2399433
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC3 mRNA"20959002
C0352074-amino-2,6-dinitrotoluene"4-amino-2,6-dinitrotoluene affects the expression of ABCC3 mRNA"21346803
C0297284-phenylenediamine4-phenylenediamine results in increased expression of ABCC3 mRNA16314067
C0293704-toluidine4-toluidine results in increased expression of ABCC3 mRNA27638505
C0538975(6)-carboxy-2',7'-dichlorofluorescein"[ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein"24907646
C0845775-carboxyfluorescein diacetateCyclosporine inhibits the reaction [ABCC3 protein affects the export of 5-carboxyfluorescein diacetate]16636798
C0845775-carboxyfluorescein diacetateIndomethacin inhibits the reaction [ABCC3 protein affects the export of 5-carboxyfluorescein diacetate]16636798
C0845775-carboxyfluorescein diacetateVerapamil inhibits the reaction [ABCC3 protein affects the export of 5-carboxyfluorescein diacetate]16636798
D000082AcetaminophenAcetaminophen results in decreased expression of ABCC3 mRNA21420995|2223033
D000082AcetaminophenABCC3 protein affects the reaction [KEAP1 protein affects the glucuronidation of Acetaminophen]19246624
D000082AcetaminophenABCC3 protein affects the reaction [NFE2L2 protein affects the glucuronidation of Acetaminophen]19246624
D000082AcetaminophenABCC3 protein affects the susceptibility to Acetaminophen16250050
D000082AcetaminophenABCC3 protein results in increased export of Acetaminophen metabolite19246624
D000082Acetaminophen[Acetaminophen co-treated with Propylene Glycol] results in increased expression of ABCC3 mRNA17934960
D000082Acetaminophen[Acetaminophen co-treated with Sodium Chloride] results in increased expression of ABCC3 mRNA17934960
D000082AcetaminophenAcetaminophen results in increased expression of ABCC3 mRNA15496496|1793574
D000082AcetaminophenAcetaminophen results in increased expression of ABCC3 protein16177239|1793574
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of ABCC3 mRNA17585979
D000082AcetaminophenNFE2L2 protein affects the reaction [Acetaminophen results in increased expression of ABCC3 mRNA]17935745
D000082AcetaminophenNFE2L2 protein affects the reaction [Acetaminophen results in increased expression of ABCC3 protein]17935745
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ABCC3 mRNA]17585979
D000082AcetaminophenAcetaminophen results in increased expression of ABCC3 mRNA17522070
D000082Acetaminophen[allyl sulfide results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite12920174
D000082Acetaminophen[[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 protein] which results in increased export of Acetaminophen metabolite17640958
D000082Acetaminophen[oltipraz results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite12920174
D000082Acetaminophen[Phenobarbital results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite12920174
D000082Acetaminophen[stilbene oxide results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite12920174
C037386acetaminophen glucuronideacetaminophen glucuronide results in increased activity of ABCC3 protein17569508
C037386acetaminophen glucuronideABCC3 protein affects the export of acetaminophen glucuronide16250050
C037386acetaminophen glucuronideEthinyl Estradiol promotes the reaction [ABCC3 protein results in increased secretion of acetaminophen glucuronide]16554369
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC3 protein]11820781
D020106AcrylamideAcrylamide results in increased expression of ABCC3 mRNA28959563
D000255Adenosine TriphosphateAdenosine Triphosphate promotes the reaction [ABCC3 protein affects the transport of fexofenadine]18245269
C560978aegeline[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC3 mRNA28843594
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of ABCC3 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of ABCC3 mRNA22545673|2305219
C008088alfacalcidolalfacalcidol results in increased expression of ABCC3 mRNA19581390
C103303alitretinoinalitretinoin results in increased expression of ABCC3 mRNA15824121
C006463allyl alcoholallyl alcohol results in increased expression of ABCC3 mRNA19371622
C038491allyl sulfideallyl sulfide affects the expression of ABCC3 mRNA22397993
C038491allyl sulfide[allyl sulfide results in increased activity of NR1I3 protein] which results in increased expression of ABCC3 mRNA15833929
C038491allyl sulfideallyl sulfide results in increased expression of ABCC3 mRNA15833929
C038491allyl sulfideallyl sulfide results in increased expression of ABCC3 mRNA11752103|1292017
C038491allyl sulfideallyl sulfide results in increased expression of ABCC3 protein12920174
C038491allyl sulfide[allyl sulfide results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite12920174
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of ABCC3 mRNA17003774
C040534alpha-hexachlorocyclohexanealpha-hexachlorocyclohexane results in increased expression of ABCC3 mRNA17785943
D000583AmikacinAmikacin results in decreased expression of ABCC3 mRNA27765674
D000638AmiodaroneAmiodarone results in increased expression of ABCC3 mRNA24489787
D000638AmiodaroneAmiodarone results in decreased expression of ABCC3 mRNA27765674
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of ABCC3 mRNA"22863853
D000667AmpicillinAmpicillin results in decreased expression of ABCC3 mRNA21632981
D000841AnisomycinAnisomycin results in increased expression of ABCC3 mRNA27507784
D000841AnisomycinSB 203580 inhibits the reaction [Anisomycin results in increased expression of ABCC3 mRNA]27507784
C010680antibiotic G 418ABCC3 protein results in increased transport of antibiotic G 41820018165
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of ABCC3 mRNA24449571
C000228aristolochic acid I[aristolochic acid I co-treated with aristolochic acid II] results in increased expression of ABCC3 mRNA23912714
C000228aristolochic acid Iaristolochic acid I results in increased expression of ABCC3 mRNA17483316
C042310aristolochic acid II[aristolochic acid I co-treated with aristolochic acid II] results in increased expression of ABCC3 mRNA23912714
C006632arsenic trioxideABCC3 protein results in decreased susceptibility to arsenic trioxide20707922
C006632arsenic trioxidearsenic trioxide results in decreased expression of ABCC3 mRNA22214486
C006632arsenic trioxidearsenic trioxide results in increased expression of ABCC3 mRNA22580103
C015001arsenitearsenite results in decreased methylation of ABCC3 promoter23974009
C031327artemisinineartemisinine inhibits the reaction [Simvastatin results in increased nitrosation of ABCC3 protein]18463201
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased expression of ABCC3 mRNA15986414
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased expression of ABCC3 protein15986414
D001379AzathioprineAzathioprine results in increased expression of ABCC3 mRNA27765674
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of ABCC3 mRNA26377693
D019324beta-Naphthoflavone[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC3 mRNA15833929
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of ABCC3 mRNA15833929|2399433
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of ABCC3 mRNA19118567
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ABCC3 mRNA16545412|2010694
D004958Estradiol[Cycloheximide co-treated with Estradiol] results in increased expression of ABCC3 mRNA15072547
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ABCC3 mRNA19619570
D004958EstradiolEstradiol results in decreased expression of ABCC3 mRNA15072547|2301914
D004958EstradiolEstradiol results in increased expression of ABCC3 mRNA19619570|2118537
D004958Estradiol[Progesterone co-treated with Estradiol] results in decreased expression of ABCC3 mRNA17404688
C023888beta-hexachlorocyclohexanebeta-hexachlorocyclohexane results in increased expression of ABCC3 mRNA28392238
D001647Bile Acids and SaltsABCC3 protein affects the transport of Bile Acids and Salts12663868
D001647Bile Acids and SaltsBile Acids and Salts inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]12704183
D001647Bile Acids and SaltsBile Acids and Salts results in increased activity of ABCC3 protein17569508
D001647Bile Acids and SaltsTAK-875 inhibits the reaction [ABCC3 protein results in increased transport of Bile Acids and Salts]28108665
D001647Bile Acids and SaltsBile Acids and Salts results in increased expression of ABCC3 mRNA12809945
C543008bis(4-hydroxyphenyl)sulfone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ABCC3 mRNA28628672
C006780bisphenol Abisphenol A results in increased expression of ABCC3 mRNA18634814|2927551
C006780bisphenol Abisphenol A results in increased expression of ABCC3 protein18634814
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABCC3 mRNA28628672
C006780bisphenol A"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of ABCC3 mRNA"28433925
C006780bisphenol Abisphenol A results in increased expression of ABCC3 mRNA25181051
C512161bisphenol A glucuronidebisphenol A glucuronide binds to ABCC3 protein22552776
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ABCC3 mRNA28628672
C584056BMS-764459BMS-764459 results in increased expression of ABCC3 mRNA23831372
C086232bosentanbosentan results in decreased expression of ABCC3 mRNA28369585
C086232bosentanbosentan results in increased expression of ABCC3 mRNA27765674
C032036bromobenzenebromobenzene results in increased expression of ABCC3 mRNA17538237
D002064Buserelin[Buserelin co-treated with CGB3 protein] results in increased expression of ABCC3 mRNA19955106
D002083Butylated Hydroxyanisole[Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA15833929
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of ABCC3 mRNA15833929
C027561butylbenzyl phthalatebutylbenzyl phthalate results in increased expression of ABCC3 mRNA26519955
C018475butyraldehydebutyraldehyde results in decreased expression of ABCC3 mRNA26079696
C584509C646 compoundC646 compound results in increased expression of ABCC3 mRNA26191083
D002101Cacodylic AcidCacodylic Acid results in increased expression of ABCC3 mRNA16436460
D002101Cacodylic AcidCacodylic Acid results in increased expression of ABCC3 protein16436460
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of ABCC3 mRNA25596134
D019256Cadmium ChlorideCadmium Chloride results in increased expression of ABCC3 mRNA22580103
C055494caffeic acid phenethyl ester[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCC3 mRNA20360939
D002110Caffeine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC3 mRNA28843594
C085925calcein AMABCC3 protein affects the transport of calcein AM15979871
C085925calcein AMABCC3 protein results in increased transport of calcein AM19647055
C085925calcein AMDexamethasone promotes the reaction [ABCC3 protein affects the transport of calcein AM]15979871
C085925calcein AMGlutathione promotes the reaction [ABCC3 protein affects the transport of calcein AM]15210835
C085925calcein AMHydrocortisone promotes the reaction [ABCC3 protein affects the transport of calcein AM]15979871
C085925calcein AMPrednisone promotes the reaction [ABCC3 protein affects the transport of calcein AM]15979871
C085925calcein AMverlukast inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]19647055
C085925calcein AMzearalenol inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]19647055
C085925calcein AMZearalenone inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]19647055
D002220CarbamazepineCarbamazepine results in increased expression of ABCC3 mRNA17381134
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of ABCC3 mRNA27339419
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of ABCC3 protein16177239
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of ABCC3 mRNA15496496
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of ABCC3 mRNA17522070
D002512Cephalothin[Cephalothin co-treated with Neomycin] results in increased expression of ABCC3 mRNA24657338
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in increased expression of ABCC3 mRNA20888898|2505596
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in increased expression of ABCC3 mRNA25582706
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in increased expression of ABCC3 mRNA20888898|2774386
C004656chloroacetaldehydechloroacetaldehyde results in decreased expression of ABCC3 mRNA25596134
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of ABCC3 mRNA18178546
D002725ChloroformChloroform results in increased expression of ABCC3 mRNA17522070
D002737ChloropreneChloroprene results in increased expression of ABCC3 mRNA23125180
D002746ChlorpromazineChlorpromazine analog results in increased expression of ABCC3 mRNA15924885
D002746ChlorpromazineChlorpromazine results in decreased expression of ABCC3 mRNA25596134
D004390ChlorpyrifosChlorpyrifos results in increased expression of ABCC3 mRNA21356183
D020355CholatesCholates results in increased activity of ABCC3 protein17569508
D019826Cholic AcidCholic Acid results in increased expression of ABCC3 mRNA25055961
D019826Cholic AcidCholic Acid results in increased expression of ABCC3 mRNA12971955|2558270
D002793Cholic Acids[Methyltestosterone co-treated with Cholic Acids] affects the expression of ABCC3 mRNA27344345
D002794Choline[LEP gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 mRNA24384915
D002794Choline[LEPR gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 mRNA24384915
D002794Choline[LEPR gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 protein24384915
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ABCC3 mRNA20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 mRNA17640958|2438491
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 protein17640958|2438491
D002794Choline[[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 protein] which results in increased export of Acetaminophen metabolite17640958
C043561chrysinABCC3 protein affects the reaction [chrysin results in increased transport of Glutathione]21856323
C012843cinnamic aldehydecinnamic aldehyde results in increased expression of ABCC3 mRNA19524605
C019304ciprofibrate[ciprofibrate binds to PPARA protein] which results in increased expression of ABCC3 mRNA15833929
C019304ciprofibrateciprofibrate results in increased expression of ABCC3 mRNA15833929
D002939CiprofloxacinCiprofloxacin results in increased expression of ABCC3 mRNA24657338
D004002Clodronic AcidClodronic Acid results in increased expression of ABCC3 mRNA25596134
D002994Clofibrate[Clofibrate binds to PPARA protein] which results in increased expression of ABCC3 mRNA15833929
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of ABCC3 mRNA17585979
D002994ClofibrateClofibrate results in increased expression of ABCC3 mRNA15833929|1646745
D002994ClofibrateClofibrate results in increased expression of ABCC3 protein16467456
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ABCC3 mRNA]17585979
D002994ClofibratePPARA promotes the reaction [Clofibrate results in increased expression of ABCC3 mRNA]16467456
D002994ClofibratePPARA promotes the reaction [Clofibrate results in increased expression of ABCC3 protein]16467456
D003022ClotrimazoleClotrimazole results in increased expression of ABCC3 mRNA27507784
D003022ClotrimazoleMAPK14 promotes the reaction [Clotrimazole results in increased expression of ABCC3 mRNA]27507784
D003022ClotrimazoleSB 203580 inhibits the reaction [Clotrimazole results in increased expression of ABCC3 mRNA]27507784
C018021cobaltous chloridecobaltous chloride results in decreased expression of ABCC3 mRNA19376846
C018021cobaltous chloridecobaltous chloride results in increased expression of ABCC3 mRNA24386269
D003042CocaineCocaine affects the expression of ABCC3 mRNA20187946
C004690coclaurine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC3 mRNA28843594
D003078ColchicineColchicine affects the localization of ABCC3 protein12702492
C075384coniferaldehydeconiferaldehyde results in increased expression of ABCC3 mRNA26275128
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of ABCC3 mRNA20971185
D019327Copper SulfateCopper Sulfate results in increased expression of ABCC3 mRNA16283523|1954981
C030123coumarincoumarin results in increased expression of ABCC3 mRNA18480146
D003471CuprizoneCuprizone results in increased expression of ABCC3 mRNA27523638
D003513Cycloheximide[Cycloheximide co-treated with Estradiol] results in increased expression of ABCC3 mRNA15072547
D003513CycloheximideCycloheximide results in increased expression of ABCC3 mRNA15072547
D016572CyclosporineCyclosporine affects the expression of ABCC3 mRNA24973091
D016572CyclosporineCyclosporine inhibits the reaction [ABCC3 protein affects the export of 5-carboxyfluorescein diacetate]16636798
D016572CyclosporineCyclosporine results in decreased expression of ABCC3 mRNA20106945|2559613
D016572CyclosporineCyclosporine results in increased expression of ABCC3 mRNA25562108
D016572CyclosporineCyclosporine results in decreased expression of ABCC3 mRNA19770486
D016572CyclosporineCyclosporine results in decreased expression of ABCC3 mRNA25596134
C093628cyproconazole[NR1I2 protein co-treated with NR1I3 protein] affects the reaction [cyproconazole results in increased expression of ABCC3 mRNA]28058446
C093628cyproconazole[NR1I2 protein co-treated with NR1I3 protein] affects the reaction [cyproconazole results in increased expression of ABCC3 protein]28058446
C093628cyproconazolecyproconazole results in increased expression of ABCC3 mRNA22334560|2805844
C093628cyproconazolecyproconazole results in increased expression of ABCC3 protein28058446
C093628cyproconazole[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCC3 mRNA29038839
C093628cyproconazole[cyproconazole co-treated with epoxiconazole] results in increased expression of ABCC3 mRNA29038839
C093628cyproconazolecyproconazole results in increased expression of ABCC3 mRNA29038839
D000069439DasatinibDasatinib results in increased expression of ABCC3 mRNA20579391
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of ABCC3 mRNA23914054
C014347decitabinedecitabine results in increased expression of ABCC3 mRNA11509559|2313791
C014347decitabineRifampin inhibits the reaction [decitabine results in increased expression of ABCC3 mRNA]23137910
D003840Deoxycholic AcidDeoxycholic Acid results in increased activity of ABCC3 protein17569508
D003840Deoxycholic AcidDeoxycholic Acid results in increased expression of ABCC3 mRNA25055961
D003840Deoxycholic AcidDeoxycholic Acid affects the expression of ABCC3 mRNA21914718
D003840Deoxycholic AcidDeoxycholic Acid results in decreased expression of ABCC3 mRNA25582706
D003840Deoxycholic AcidSLCO1A1 protein affects the susceptibility to [Deoxycholic Acid affects the expression of ABCC3 mRNA]21914718
D003907DexamethasoneDexamethasone promotes the reaction [ABCC3 protein affects the transport of calcein AM]15979871
D003907DexamethasoneDexamethasone results in increased activity of ABCC3 protein15979871
D003907DexamethasoneDexamethasone results in increased expression of ABCC3 mRNA15979871|2504701
D003907DexamethasoneDexamethasone results in increased expression of ABCC3 protein15979871
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ABCC3 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABCC3 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ABCC3 mRNA28628672
D003907DexamethasoneDexamethasone affects the expression of ABCC3 mRNA15102944
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of ABCC3 mRNA]15205389
D003907DexamethasoneDexamethasone results in decreased expression of ABCC3 mRNA15102944|1752207
D003907DexamethasoneDexamethasone results in decreased expression of ABCC3 protein19922765
D003907DexamethasoneDexamethasone results in increased expression of ABCC3 protein15908472
D016264Dextran SulfateDextran Sulfate results in decreased expression of ABCC3 mRNA27580383
D016264Dextran SulfateDextran Sulfate results in decreased expression of ABCC3 protein27580383
C028009diallyl disulfidediallyl disulfide affects the expression of ABCC3 mRNA22397993
C028009diallyl disulfidediallyl disulfide results in increased expression of ABCC3 mRNA22397993
C042577diallyl trisulfidediallyl trisulfide results in decreased expression of ABCC3 mRNA22397993
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of ABCC3 mRNA28962523
D002945CisplatinABCC3 mRNA affects the susceptibility to Cisplatin18610736
D002945CisplatinABCC3 protein results in decreased susceptibility to Cisplatin17982673
D002945CisplatinCisplatin results in increased expression of ABCC3 mRNA20737486
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in decreased expression of ABCC3 mRNA26924002
D004041Dietary FatsDietary Fats affects the expression of ABCC3 mRNA19680557
D004041Dietary Fats[Dietary Fats co-treated with sodium arsenite] results in increased expression of ABCC3 mRNA26890134
D004051Diethylhexyl Phthalate[Diethylhexyl Phthalate binds to PPARA protein] which results in increased expression of ABCC3 mRNA15833929
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of ABCC3 mRNA15833929|1985064
D004051Diethylhexyl Phthalate"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of ABCC3 mRNA"28433925
D004052Diethylnitrosamine[Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of ABCC3 mRNA19690152
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCC3 mRNA20360939
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of ABCC3 mRNA18648771
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of ABCC3 mRNA19638242|2036093
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCC3 mRNA22129741
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of ABCC3 mRNA19371625
D002117CalcitriolCalcitriol results in increased expression of ABCC3 mRNA15824121
D002117CalcitriolCalcitriol results in increased expression of ABCC3 mRNA15824121
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ABCC3 mRNA"22485181
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of ABCC3 mRNA17547211
C024629dimethyl phthalatedimethyl phthalate results in decreased expression of ABCC3 mRNA26924002
C010715di-n-octyl phthalatedi-n-octyl phthalate results in increased expression of ABCC3 mRNA26519955
D004144DiosgeninDiosgenin results in increased expression of ABCC3 mRNA16105132
D004144Diosgenin[Ethinyl Estradiol co-treated with Diosgenin] results in increased expression of ABCC3 mRNA16105132
C067311docetaxel[docetaxel results in decreased susceptibility to docetaxel] which results in increased expression of ABCC3 mRNA19944135
D004317DoxorubicinABCC3 protein results in decreased susceptibility to Doxorubicin15695394|1588411
D004317DoxorubicinDoxorubicin results in increased nitrosation of ABCC3 protein18463201
D004317DoxorubicinSimvastatin promotes the reaction [Doxorubicin results in increased nitrosation of ABCC3 protein]18463201
D004318DoxycyclineDoxycycline results in decreased expression of ABCC3 mRNA27765674
D004642EmodinEmodin results in decreased expression of ABCC3 mRNA28161596
D004642EmodinEmodin results in decreased expression of ABCC3 protein28161596
D004642EmodinEmodin results in increased expression of ABCC3 mRNA19549930
C109476epoxiconazoleepoxiconazole results in increased expression of ABCC3 mRNA22334560
C109476epoxiconazole[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCC3 mRNA29038839
C109476epoxiconazole[cyproconazole co-treated with epoxiconazole] results in increased expression of ABCC3 mRNA29038839
D004918Erythromycin EstolateErythromycin Estolate results in increased expression of ABCC3 mRNA17522070|2441256
C025483estradiol-17 beta-glucuronideABCC3 protein affects the transport of estradiol-17 beta-glucuronide12704183
C025483estradiol-17 beta-glucuronideABCC3 protein results in increased transport of estradiol-17 beta-glucuronide19114588
C025483estradiol-17 beta-glucuronideBile Acids and Salts inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]12704183
C025483estradiol-17 beta-glucuronideestradiol-17 beta-glucuronide results in increased activity of ABCC3 protein17569508
C025483estradiol-17 beta-glucuronideEthinyl Estradiol metabolite promotes the reaction [ABCC3 protein results in increased uptake of estradiol-17 beta-glucuronide]14722317
C025483estradiol-17 beta-glucuronideFurosemide inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]12704183
C025483estradiol-17 beta-glucuronideIndomethacin inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]12704183
C025483estradiol-17 beta-glucuronideProbenecid inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]12704183
C025483estradiol-17 beta-glucuronideresveratrol-4'-O-glucuronide inhibits the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide]19114588
C025483estradiol-17 beta-glucuronideresveratrol metabolite promotes the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide]19114588
D000431EthanolEthanol results in increased expression of ABCC3 mRNA19167417
D000431EthanolEthanol results in increased expression of ABCC3 mRNA15353170
D004997Ethinyl EstradiolABCC3 protein results in increased uptake of Ethinyl Estradiol metabolite14722317
D004997Ethinyl EstradiolEthinyl Estradiol metabolite promotes the reaction [ABCC3 protein results in increased uptake of estradiol-17 beta-glucuronide]14722317
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of ABCC3 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of ABCC3 mRNA17942748|2781822
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ABCC3 mRNA17942748
D004997Ethinyl Estradiol[Ethinyl Estradiol co-treated with Diosgenin] results in increased expression of ABCC3 mRNA16105132
D004997Ethinyl Estradiol[Ethinyl Estradiol co-treated with Spironolactone] results in increased expression of ABCC3 protein17686906
D004997Ethinyl EstradiolEthinyl Estradiol promotes the reaction [ABCC3 protein results in increased secretion of acetaminophen glucuronide]16554369
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of ABCC3 mRNA16105132|1768690
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of ABCC3 protein16554369|1768690
C024860ethinyl estradiol glucuronideethinyl estradiol glucuronide results in increased activity of ABCC3 protein17569508
D005015Ethoxyquin[Ethoxyquin results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA15833929
D005015EthoxyquinEthoxyquin results in increased expression of ABCC3 mRNA15833929
D005047EtoposideABCC3 protein results in decreased susceptibility to Etoposide15884115
D015025ZearalenoneZearalenone inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]19647055
D015025ZearalenoneZearalenone results in decreased expression of ABCC3 mRNA19371625
D015025ZearalenoneZearalenone affects the expression of ABCC3 mRNA22521637
D015025ZearalenoneZearalenone affects the expression of ABCC3 protein22521637
C047360felbamatefelbamate results in increased expression of ABCC3 mRNA17381134
D011345FenofibrateFenofibrate results in decreased expression of ABCC3 mRNA25596134
C093230fexofenadineABCC3 protein affects the transport of fexofenadine18245269
C093230fexofenadineAdenosine Triphosphate promotes the reaction [ABCC3 protein affects the transport of fexofenadine]18245269
C082360fipronilfipronil results in increased expression of ABCC3 mRNA23962444
C082360fipronilNR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of ABCC3 mRNA]23962444
C082360fipronilfipronil results in increased expression of ABCC3 mRNA23962444
D005419FlavonoidsFlavonoids results in increased expression of ABCC3 mRNA18035473
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of ABCC3 mRNA10691972
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of ABCC3 protein10691972
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of ABCC3 mRNA12801967
D005485FlutamideFlutamide results in decreased expression of ABCC3 mRNA24793618
D005485FlutamideFlutamide results in increased expression of ABCC3 mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ABCC3 mRNA20938992
D005557FormaldehydeFormaldehyde results in increased expression of ABCC3 mRNA27664576
D015378Imipenem[Vancomycin co-treated with Imipenem] results in decreased expression of ABCC3 mRNA24657338
C070081fulvestrantfulvestrant results in increased expression of ABCC3 mRNA15072547
C039281furanfuran results in increased expression of ABCC3 mRNA25539665
D005665FurosemideFurosemide inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]12704183
D019833GenisteinGenistein results in decreased expression of ABCC3 mRNA19371625
D005978GlutathioneABCC3 protein affects the reaction [chrysin results in increased transport of Glutathione]21856323
D005978GlutathioneGlutathione promotes the reaction [ABCC3 protein affects the transport of calcein AM]15210835
D005905GlyburideGlyburide results in increased expression of ABCC3 mRNA27765674
D019695Glycyrrhizic AcidGlycyrrhizic Acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA]28549656
C412815GW 4064GW 4064 results in increased expression of ABCC3 mRNA27609522
D006581HexachlorobenzeneHexachlorobenzene results in increased expression of ABCC3 mRNA23153324
C001335hexachlorobutadienehexachlorobutadiene results in increased expression of ABCC3 mRNA21905055
C012348higenamine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC3 mRNA28843594
D017313FenretinideFenretinide results in increased expression of ABCC3 mRNA28973697
D006854HydrocortisoneHydrocortisone promotes the reaction [ABCC3 protein affects the transport of calcein AM]15979871
D006854HydrocortisoneHydrocortisone results in increased activity of ABCC3 protein15979871
D006854HydrocortisoneHydrocortisone results in increased expression of ABCC3 mRNA15979871
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of ABCC3 mRNA20044591
D047348Hydrolyzable Tannins[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC3 mRNA28843594
C475919hydroxytamoxifenhydroxytamoxifen results in increased expression of ABCC3 mRNA15072547
C492448ICG 001ICG 001 results in increased expression of ABCC3 mRNA26191083
C016517indole-3-carbinolindole-3-carbinol affects the expression of ABCC3 mRNA21396975
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCC3 mRNA22129741
D007213IndomethacinIndomethacin inhibits the reaction [ABCC3 protein affects the export of 5-carboxyfluorescein diacetate]16636798
D007213IndomethacinIndomethacin inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]12704183
D007213IndomethacinIndomethacin results in increased expression of ABCC3 protein11820781
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ABCC3 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABCC3 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ABCC3 mRNA28628672
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ABCC3 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ABCC3 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABCC3 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ABCC3 mRNA28628672
D007545IsoproterenolIsoproterenol results in decreased expression of ABCC3 mRNA24286936
D007545IsoproterenolIsoproterenol results in decreased expression of ABCC3 mRNA21335049
D007545IsoproterenolIsoproterenol results in decreased expression of ABCC3 mRNA24286936
D007545IsoproterenolIsoproterenol results in increased expression of ABCC3 mRNA24286936
C410337K 7174K 7174 results in increased expression of ABCC3 mRNA24086573
C099406L 742694L 742694 affects the expression of ABCC3 mRNA15102944
C099406L 742694L 742694 results in increased expression of ABCC3 mRNA15102944
D007854LeadLead results in increased expression of ABCC3 mRNA19921347
C052901lemongrass oillemongrass oil affects the expression of ABCC3 mRNA25976427
D001556LindaneLindane results in increased expression of ABCC3 mRNA17785943
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in decreased expression of ABCC3 mRNA"22942241
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in decreased expression of ABCC3 mRNA"23939143
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of ABCC3 mRNA15313196
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of ABCC3 mRNA]15205389
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of ABCC3 mRNA15205389
D008095Lithocholic AcidLithocholic Acid results in increased activity of ABCC3 protein14570758
D008095Lithocholic Acid[Lithocholic Acid results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D008095Lithocholic AcidLithocholic Acid results in increased expression of ABCC3 mRNA14570758|2088889
D008095Lithocholic Acid"[Lithocholic Acid co-treated with 1,4-bis(2-(3,5-dichloropyridyloxy))benzene] results in increased expression of ABCC3 mRNA"18032408
D008095Lithocholic AcidLithocholic Acid results in decreased expression of ABCC3 mRNA25582706
D008095Lithocholic AcidLithocholic Acid results in increased expression of ABCC3 mRNA15358766|1582412
D008095Lithocholic AcidLithocholic Acid results in increased expression of ABCC3 protein16436656
D008095Lithocholic AcidNFE2L2 protein promotes the reaction [Lithocholic Acid results in increased expression of ABCC3 mRNA]20977460
D008095Lithocholic AcidNR1I3 protein affects the reaction [Lithocholic Acid results in increased expression of ABCC3 mRNA]15358766
D008095Lithocholic AcidABCC3 protein affects the export of Lithocholic Acid15824121
D008095Lithocholic AcidLithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which results in increased expression of ABCC3]15824121
D017997Leukotriene C4verlukast inhibits the reaction [ABCC3 protein results in increased transport of Leukotriene C4]27676153
C533860macitentanmacitentan results in decreased expression of ABCC3 mRNA28369585
D008610MentholMenthol results in increased expression of ABCC3 mRNA24594507
D008627Mercuric ChlorideMercuric Chloride results in increased expression of ABCC3 mRNA22580103
D008687MetforminMetformin results in decreased expression of ABCC3 mRNA25596134
D008701MethapyrileneMethapyrilene results in decreased expression of ABCC3 mRNA28935588
D008701MethapyrileneMethapyrilene results in increased expression of ABCC3 mRNA28935588
D008713MethimazoleMethimazole results in increased expression of ABCC3 mRNA22504374
D008715Methionine[LEP gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 mRNA24384915
D008715Methionine[LEPR gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 mRNA24384915
D008715Methionine[LEPR gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 protein24384915
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ABCC3 mRNA20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 mRNA17640958|2438491
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 protein17640958|2438491
D008715Methionine[[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC3 protein] which results in increased export of Acetaminophen metabolite17640958
D008727MethotrexateABCC3 gene mutant form affects the susceptibility to Methotrexate19426680
D008727MethotrexateABCC3 gene SNP affects the susceptibility to Methotrexate22859359
D008727MethotrexateMethotrexate affects the expression of ABCC3 mRNA23897011
D008727MethotrexateABCC3 mRNA results in decreased susceptibility to Methotrexate16918715
D008730MethoxsalenMethoxsalen results in increased expression of ABCC3 mRNA28552422
D008748MethylcholanthreneMethylcholanthrene results in increased expression of ABCC3 mRNA19118567
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of ABCC3 mRNA22129749
D008777Methyltestosterone[Methyltestosterone co-treated with Cholic Acids] affects the expression of ABCC3 mRNA27344345
D008795MetronidazoleMetronidazole results in increased expression of ABCC3 mRNA24657338
D008797MetyraponeMetyrapone results in increased activity of ABCC3 protein14570758
D008797Metyrapone[Metyrapone results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D008797MetyraponeMetyrapone results in increased expression of ABCC3 mRNA14570758
D015735MifepristoneMifepristone results in increased activity of ABCC3 protein14570758
D015735Mifepristone[Mifepristone results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D015735MifepristoneMifepristone results in increased expression of ABCC3 mRNA14570758
D015735MifepristoneMifepristone results in increased expression of ABCC3 mRNA14570758|1545684
C020300monomethylarsonic acidmonomethylarsonic acid results in increased expression of ABCC3 mRNA16436460
C020300monomethylarsonic acidmonomethylarsonic acid results in increased expression of ABCC3 protein16436460
C517284monomethyl phthalatemonomethyl phthalate results in decreased expression of ABCC3 mRNA26924002
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of ABCC3 mRNA"29244179
D009270NaloxoneNaloxone results in increased expression of ABCC3 mRNA17522070
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of ABCC3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of ABCC3 mRNA"25620056
D0150581-Naphthylisothiocyanate18alpha-glycyrrhetinic acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA]28549656
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA28549656
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA19181614|1940733
D0150581-NaphthylisothiocyanateGlycyrrhizic Acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA]28549656
D0150581-NaphthylisothiocyanateNFE2L2 promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA]19181614
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA14623915|1752207
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of ABCC3 protein25418378
D0150581-Naphthylisothiocyanateresveratrol inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA]25418378
D0150581-Naphthylisothiocyanateresveratrol inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 protein]25418378
D0150581-NaphthylisothiocyanateUrsodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 protein]25418378
C051752nefazodonenefazodone results in increased expression of ABCC3 mRNA24136188
D009355Neomycin[Cephalothin co-treated with Neomycin] results in increased expression of ABCC3 mRNA24657338
C119536nickel acetatenickel acetate affects the expression of ABCC3 mRNA12915101
C029938nickel sulfatenickel sulfate results in increased expression of ABCC3 mRNA16314067|2271453
D009543NifedipineNifedipine results in increased activity of ABCC3 protein14570758
D009543Nifedipine[Nifedipine results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D009543NifedipineNifedipine results in increased expression of ABCC3 mRNA14570758
C012655nimesulidenimesulide results in increased expression of ABCC3 mRNA24136188
D015739NocodazoleNocodazole results in increased expression of ABCC3 mRNA10691972
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of ABCC3 mRNA20971185
C042670N-vinyl-2-pyrrolidinone[N-vinyl-2-pyrrolidinone binds to N-vinyl-2-pyrrolidinone] which results in increased expression of ABCC3 mRNA22037397
C026209oltiprazoltipraz results in increased expression of ABCC3 mRNA16837569
C026209oltiprazNFE2L2 protein affects the reaction [oltipraz results in increased expression of ABCC3 mRNA]22496397
C026209oltipraz[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA15833929|2249639
C026209oltiprazoltipraz results in increased expression of ABCC3 mRNA15833929|2249639
C026209oltiprazoltipraz results in increased expression of ABCC3 mRNA12920174
C026209oltiprazoltipraz results in increased expression of ABCC3 protein12920174
C026209oltipraz[oltipraz results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite12920174
D009853OmeprazoleOmeprazole results in increased expression of ABCC3 mRNA19118567
D009966OrphenadrineOrphenadrine affects the expression of ABCC3 mRNA23665939
D017239PaclitaxelPaclitaxel results in increased expression of ABCC3 mRNA20737486
D000073878Palm OilPalm Oil affects the expression of ABCC3 mRNA19680557
C002669parthenolideparthenolide inhibits the reaction [Simvastatin results in increased nitrosation of ABCC3 protein]18463201
D052638Particulate MatterParticulate Matter results in increased expression of ABCC3 mRNA24769257|2580327
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of ABCC3 mRNA18978342
D010416PentachlorophenolPentachlorophenol results in increased expression of ABCC3 mRNA23892564
C036567perfluorodecanoic acidNFE2L2 protein affects the reaction [perfluorodecanoic acid results in increased expression of ABCC3 mRNA]18757529
C036567perfluorodecanoic acidperfluorodecanoic acid results in increased expression of ABCC3 mRNA18757529
C036567perfluorodecanoic acidPPARA protein affects the reaction [perfluorodecanoic acid results in increased expression of ABCC3 mRNA]18757529
C584865perfluorononanoic acidperfluorononanoic acid results in increased expression of ABCC3 mRNA29112762
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in decreased expression of ABCC3 mRNA23602845
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of ABCC3 mRNA19162173
C023036perfluorooctanoic acidperfluorooctanoic acid affects the expression of ABCC3 mRNA18281256
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of ABCC3 mRNA19162173
D010480PerhexilinePerhexiline results in decreased expression of ABCC3 mRNA27765674
C031181phenanthrenephenanthrene results in increased expression of ABCC3 mRNA21362169
D010634PhenobarbitalNR1I3 protein promotes the reaction [Phenobarbital results in increased expression of ABCC3 mRNA]19850644
D010634PhenobarbitalPhenobarbital results in increased expression of ABCC3 mRNA15833929|1598641
D010634PhenobarbitalPhenobarbital results in increased expression of ABCC3 protein15986414
D010634PhenobarbitalPhenobarbital results in increased expression of ABCC3 mRNA11752103|1292017
D010634PhenobarbitalPhenobarbital results in increased expression of ABCC3 protein12920174|1590847
D010634Phenobarbital[Phenobarbital results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite12920174
C033457phenobarbital quinidine[phenobarbital quinidine results in increased activity of NR1I3 protein] which results in increased expression of ABCC3 mRNA15833929
D010672PhenytoinPhenytoin results in increased expression of ABCC3 mRNA17381134
C008905physcionephyscione results in decreased expression of ABCC3 mRNA28161596
C008905physcionephyscione results in decreased expression of ABCC3 protein28161596
D010882Piperonyl Butoxide[Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of ABCC3 mRNA19690152
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of ABCC3 mRNA19690152
D010882Piperonyl Butoxide[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of ABCC3 mRNA18648771
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of ABCC3 mRNA17498859|2248451
C027260pirarubicinABCC3 protein results in decreased susceptibility to pirarubicin15884115
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCC3 mRNA19710929
C006253pirinixic acidpirinixic acid results in increased expression of ABCC3 mRNA18301758|1917653
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in decreased expression of ABCC3 mRNA]19850644
C006253pirinixic acidRXRA protein affects the reaction [pirinixic acid results in increased expression of ABCC3 mRNA]19176532
C006253pirinixic acidpirinixic acid results in increased expression of ABCC3 mRNA19631232
D028321Plant PreparationsPlant Preparations results in increased expression of ABCC3 mRNA18047722
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of ABCC3 mRNA22714537
D011192Potassium DichromatePotassium Dichromate results in decreased expression of ABCC3 mRNA23608068
D011192Potassium DichromatePotassium Dichromate results in increased expression of ABCC3 mRNA22580103
D017035PravastatinPravastatin results in increased expression of ABCC3 protein24909372
D011241PrednisonePrednisone promotes the reaction [ABCC3 protein affects the transport of calcein AM]15979871
D011241PrednisonePrednisone results in increased activity of ABCC3 protein15979871
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased activity of ABCC3 protein14570758
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of ABCC3 mRNA14570758
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of ABCC3 mRNA]22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile binds to NR1I2 protein] which results in increased expression of ABCC3 mRNA15833929
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ABCC3 gene]20693526
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ABCC3 gene]] which results in increased expression of ABCC3 mRNA20693526|2069352
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA22496397
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of ABCC3 mRNA15456840|1583392
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of ABCC3 protein15986414
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of ABCC3 mRNA19162173
D011339ProbenecidProbenecid inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]12704183
C045362prochloraz[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCC3 mRNA29038839
D011374Progesterone[Progesterone co-treated with Estradiol] results in decreased expression of ABCC3 mRNA17404688
D011374ProgesteroneProgesterone results in increased expression of ABCC3 mRNA21795739
D011374ProgesteroneProgesterone results in decreased expression of ABCC3 mRNA22238285
D019946Propylene Glycol[Acetaminophen co-treated with Propylene Glycol] results in increased expression of ABCC3 mRNA17934960
C045950propiconazolepropiconazole results in increased expression of ABCC3 mRNA21278054|2233456
C045950propiconazolepropiconazole results in increased expression of ABCC3 mRNA19409404
C005556propionaldehydepropionaldehyde results in decreased expression of ABCC3 mRNA26079696
D011441PropylthiouracilPropylthiouracil results in increased expression of ABCC3 mRNA22504374|2478091
D011718PyrazinamidePyrazinamide results in increased expression of ABCC3 mRNA27255380
D011718PyrazinamidePyrazinamide results in increased expression of ABCC3 protein27255380
D011759PyrrolidinesPyrrolidines analog results in increased expression of ABCC3 mRNA26365562
C059514resveratrolresveratrol metabolite promotes the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide]19114588
C059514resveratrolresveratrol results in increased expression of ABCC3 mRNA18634814
C059514resveratrolresveratrol results in increased expression of ABCC3 protein18634814
C059514resveratrol[resveratrol co-treated with Streptozocin] results in increased expression of ABCC3 mRNA25905778
C059514resveratrolresveratrol inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA]25418378
C059514resveratrolresveratrol inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 protein]25418378
C499731resveratrol-4'-O-glucuronideABCC3 protein results in increased transport of resveratrol-4'-O-glucuronide19114588
C499731resveratrol-4'-O-glucuronideresveratrol-4'-O-glucuronide inhibits the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide]19114588
C499731resveratrol-4'-O-glucuronideABCC3 protein results in increased transport of resveratrol-4'-O-glucuronide19114588
C013672riddelliineriddelliine results in increased expression of ABCC3 mRNA18047722|1804772
D012293Rifampin[Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein16952291
D012293RifampinRifampin inhibits the reaction [decitabine results in increased expression of ABCC3 mRNA]23137910
D012293RifampinRifampin results in increased activity of ABCC3 protein14570758
D012293Rifampin[Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D012293RifampinRifampin results in increased expression of ABCC3 mRNA14570758|1683756
D000068718Rosuvastatin CalciumRosuvastatin Calcium results in increased expression of ABCC3 protein24909372
C093642SB 203580SB 203580 inhibits the reaction [Anisomycin results in increased expression of ABCC3 mRNA]27507784
C093642SB 203580SB 203580 inhibits the reaction [Clotrimazole results in increased expression of ABCC3 mRNA]27507784
C009237senecioninesenecionine results in decreased expression of ABCC3 mRNA26100227
C009237senecioninesenecionine results in increased expression of ABCC3 mRNA24641316
C009238senkirkinesenkirkine results in decreased expression of ABCC3 mRNA26100227
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of ABCC3 mRNA25895662
D012834SilverSilver results in increased expression of ABCC3 mRNA25976698
D012834SilverSilver results in increased expression of ABCC3 mRNA26014281
D019821Simvastatinartemisinine inhibits the reaction [Simvastatin results in increased nitrosation of ABCC3 protein]18463201
D019821Simvastatinparthenolide inhibits the reaction [Simvastatin results in increased nitrosation of ABCC3 protein]18463201
D019821SimvastatinSimvastatin promotes the reaction [Doxorubicin results in increased nitrosation of ABCC3 protein]18463201
D019821SimvastatinSimvastatin results in increased nitrosation of ABCC3 protein18463201
D012906SmokeSmoke results in increased expression of ABCC3 mRNA21095227
C024942S-nitrosopenicillamineS-nitrosopenicillamine results in increased metabolism of ABCC3 protein15695394
C017947sodium arsenitesodium arsenite results in increased expression of ABCC3 mRNA25493608
C017947sodium arsenite[Dietary Fats co-treated with sodium arsenite] results in increased expression of ABCC3 mRNA26890134
C017947sodium arsenite"[sodium arsenite co-treated with soybean oil, phospholipid emulsion] affects the expression of ABCC3 mRNA"26890134
C016104sodium bichromatesodium bichromate results in decreased expression of ABCC3 mRNA17685462
D012965Sodium Chloride[Acetaminophen co-treated with Sodium Chloride] results in increased expression of ABCC3 mRNA17934960
D018038Sodium SeleniteSodium Selenite results in increased expression of ABCC3 mRNA24383545
C471405sorafenibABCC3 affects the susceptibility to sorafenib24244338
C545823soybean oil, phospholipid emulsion"[sodium arsenite co-treated with soybean oil, phospholipid emulsion] affects the expression of ABCC3 mRNA"26890134
C545823soybean oil, phospholipid emulsion"soybean oil, phospholipid emulsion affects the expression of ABCC3 mRNA"26890134
D013148Spironolactone[Spironolactone binds to NR1I2 protein] which results in increased expression of ABCC3 mRNA15833929
D013148SpironolactoneSpironolactone results in increased expression of ABCC3 mRNA15833929
D013148Spironolactone[Ethinyl Estradiol co-treated with Spironolactone] results in increased expression of ABCC3 protein17686906
C025906stilbene oxidestilbene oxide results in increased expression of ABCC3 mRNA12920174
C025906stilbene oxidestilbene oxide results in increased expression of ABCC3 protein12920174
C025906stilbene oxide[stilbene oxide results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite12920174
D013311StreptozocinStreptozocin results in decreased expression of ABCC3 mRNA22531820
D013311StreptozocinStreptozocin results in increased expression of ABCC3 mRNA23319174
D013311StreptozocinStreptozocin results in increased expression of ABCC3 protein23319174
D013311Streptozocin[resveratrol co-treated with Streptozocin] results in increased expression of ABCC3 mRNA25905778
D013467SulindacAcetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC3 protein]11820781
D013467SulindacSulindac results in increased expression of ABCC3 protein11820781
C446685systhanesysthane results in increased expression of ABCC3 mRNA19409404
C557331TAK-875TAK-875 inhibits the reaction [ABCC3 protein results in increased transport of Bile Acids and Salts]28108665
C557331TAK-875TAK-875 results in decreased activity of ABCC3 protein28108665
C013698tallowtallow affects the expression of ABCC3 mRNA19680557
D013629TamoxifenTamoxifen affects the expression of ABCC3 mRNA17555576
D013629TamoxifenTamoxifen results in increased expression of ABCC3 mRNA19224547
D013655Taurochenodeoxycholic AcidTaurochenodeoxycholic Acid results in increased expression of ABCC3 protein11672435
D013656Taurocholic AcidTaurocholic Acid results in increased activity of ABCC3 protein17569508
D013656Taurocholic AcidABCC3 protein affects the transport of Taurocholic Acid11557524
C037351tauromuricholic acidtauromuricholic acid results in increased expression of ABCC3 protein11672435
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in increased expression of ABCC3 protein11672435
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased expression of ABCC3 mRNA27914987
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ABCC3 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ABCC3 mRNA19619570|2010694
D013749Tetrachlorodibenzodioxin"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Tetrachlorodibenzodioxin] results in increased expression of ABCC3 mRNA"17627975
D013749TetrachlorodibenzodioxinAHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of ABCC3 mRNA]22496397
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ABCC3 mRNA18343893|2070259
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of ABCC3 mRNA15833929
D013749Tetrachlorodibenzodioxin"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of ABCC3 mRNA"28433925
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ABCC3 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ABCC3 mRNA16120747
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ABCC3 mRNA15833929|1879615
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ABCC3 mRNA21215274
D013752TetracyclineTetracycline results in increased expression of ABCC3 mRNA17522070|2776567
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ABCC3 mRNA25613284
D013853ThioacetamideThioacetamide results in increased expression of ABCC3 mRNA23411599|2622270
D013988TiclopidineTiclopidine results in increased expression of ABCC3 mRNA27765674
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of ABCC3 mRNA28065790
C116664tolvaptantolvaptan metabolite results in decreased activity of ABCC3 protein26507107
D014212TretinoinTretinoin results in increased expression of ABCC3 mRNA16249480
D014212TretinoinTretinoin results in decreased expression of ABCC3 mRNA16604517
C032910triadimefontriadimefon results in increased expression of ABCC3 mRNA19409404
D014241TrichloroethyleneTrichloroethylene results in increased methylation of ABCC3 gene27618143
C012589trichostatin Atrichostatin A results in decreased expression of ABCC3 mRNA10691972
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of ABCC3 mRNA16436460
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of ABCC3 protein16436460
D014303TrinitrotolueneTrinitrotoluene affects the expression of ABCC3 mRNA21346803
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of ABCC3 mRNA29024780
C057693troglitazonetroglitazone results in increased expression of ABCC3 mRNA19022234|2750778
C057693troglitazonetroglitazone results in increased expression of ABCC3 mRNA19022234
D014415TunicamycinTunicamycin results in decreased expression of ABCC3 mRNA17127020
D014425TurpentineTurpentine results in decreased expression of ABCC3 mRNA15313196
D014520UrethaneUrethane results in decreased expression of ABCC3 mRNA28818685
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of ABCC3 mRNA25055961
D014580Ursodeoxycholic AcidNFE2L2 affects the reaction [Ursodeoxycholic Acid results in increased expression of ABCC3 mRNA]18687751
D014580Ursodeoxycholic AcidNFE2L2 affects the reaction [Ursodeoxycholic Acid results in increased expression of ABCC3 protein]18687751
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid affects the expression of ABCC3 protein16472600
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of ABCC3 mRNA12971955|1868775
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of ABCC3 protein18687751
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 protein]25418378
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid promotes the reaction [NFE2L2 protein binds to ABCC3 promoter]18687751
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of ABCC3 mRNA16764892
C406224valdecoxibvaldecoxib results in increased expression of ABCC3 mRNA24136188
D014635Valproic AcidValproic Acid affects the expression of ABCC3 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of ABCC3 mRNA28001369
D014635Valproic AcidValproic Acid results in increased expression of ABCC3 mRNA17381134
D014640Vancomycin[Vancomycin co-treated with Imipenem] results in decreased expression of ABCC3 mRNA24657338
D001335Vehicle EmissionsVehicle Emissions results in increased expression of ABCC3 mRNA25803276
D014700VerapamilVerapamil inhibits the reaction [ABCC3 protein affects the export of 5-carboxyfluorescein diacetate]16636798
C059141verlukastverlukast inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]19647055
C059141verlukastverlukast inhibits the reaction [ABCC3 protein results in increased transport of Leukotriene C4]27676153
C059141verlukastverlukast inhibits the reaction [ABCC3 protein results in increased transport of zearalenol]19647055
D014750Vincristine[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC3 mRNA19944135
D024483Vitamin K 3Vitamin K 3 affects the expression of ABCC3 mRNA20044591
D015016Yohimbine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC3 mRNA28843594
C029659zearalenolABCC3 protein results in increased transport of zearalenol19647055
C029659zearalenolverlukast inhibits the reaction [ABCC3 protein results in increased transport of zearalenol]19647055
C029659zearalenolzearalenol inhibits the reaction [ABCC3 protein results in increased transport of calcein AM]19647055
D015215ZidovudineZidovudine results in increased expression of ABCC3 mRNA24292225
D015215ZidovudineZidovudine results in decreased expression of ABCC3 mRNA27765674

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005524ATP binding-IEA-  
GO:0008514organic anion transmembrane transporter activity-TAS9738950  
GO:0015432bile acid-exporting ATPase activity-TAS-  
GO:0042626ATPase activity, coupled to transmembrane movement of substances-IBA21873635  
GO:0042626ATPase activity, coupled to transmembrane movement of substances-TAS9813153  
GO:0043225ATPase-coupled anion transmembrane transporter activity-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0015721bile acid and bile salt transport-TAS-  
GO:0015722canalicular bile acid transport-ISS-  
GO:0055085transmembrane transport-IBA21873635  
GO:0055085transmembrane transport-TAS-  
GO:0099133ATP hydrolysis coupled anion transmembrane transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005774vacuolar membrane-IBA21873635  
GO:0005886plasma membrane-TAS-  
GO:0016020membrane-IBA21873635  
GO:0016020membrane-TAS9813153  
KEGG ID KEGG Term
hsa02010ABC transporters
hsa04976Bile secretion
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-159418Recycling of bile acids and saltsTAS
R-HSA-194068Bile acid and bile salt metabolismTAS
R-HSA-382551Transport of small moleculesTAS
R-HSA-382556ABC-family proteins mediated transportTAS
R-HSA-556833Metabolism of lipidsTAS
R-HSA-8957322Metabolism of steroidsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23462698Alcohol cirrhosis alters nuclear receptor and drug transporter expression in human liver. (2013 May)More VRDrug Metab Dispos
23054755Circulating autoantibody to ABCC3 may be a potential biomarker for esophageal squamous cell carcinoma. (2013 May)Cheng YClin Transl Oncol
22699933Are circulating autoantibodies to ABCC3 transporter a potential biomarker for lung cancer? (2012 Oct)Liu LJ Cancer Res Clin Oncol